Harvard Catalyst Profiles

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Torsten B Meissner, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Meissner TB, Schulze HS, Dale SM. Immune Editing: Overcoming Immune Barriers in Stem Cell Transplantation. Curr Stem Cell Rep. 2022; 8(4):206-218. PMID: 36406259; PMCID: PMC9643905.
  2. Van Zeebroeck L, Arroyo Hornero R, Côrte-Real BF, Hamad I, Meissner TB, Kleinewietfeld M. Fast and Efficient Genome Editing of Human FOXP3+ Regulatory T Cells. Front Immunol. 2021; 12:655122. PMID: 34408743.
    Citations: 1     Fields:    Translation:HumansCells
  3. Li Q, Meissner TB, Wang F, Du Z, Ma S, Kshirsagar S, Tilburgs T, Buenrostro JD, Uesugi M, Strominger JL. ELF3 activated by a superenhancer and an autoregulatory feedback loop is required for high-level HLA-C expression on extravillous trophoblasts. Proc Natl Acad Sci U S A. 2021 03 02; 118(9). PMID: 33622787.
    Citations: 2     Fields:    Translation:HumansCells
  4. Leite NC, Sintov E, Meissner TB, Brehm MA, Greiner DL, Harlan DM, Melton DA. Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells. Cell Rep. 2020 07 14; 32(2):107894. PMID: 32668238; PMCID: PMC7359783.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  5. Toyohara T, Roudnicky F, Florido MHC, Nakano T, Yu H, Katsuki S, Lee M, Meissner T, Friesen M, Davidow LS, Ptaszek L, Abe T, Rubin LL, Pereira AC, Aikawa M, Cowan CA. Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis. Cell Stem Cell. 2020 Jul 02; 27(1):178-180. PMID: 32619513.
    Citations: 2     Fields:    
  6. Toyohara T, Roudnicky F, Florido MHC, Nakano T, Yu H, Katsuki S, Lee M, Meissner T, Friesen M, Davidow LS, Ptaszek L, Abe T, Rubin LL, Pereira AC, Aikawa M, Cowan CA. Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis. Cell Stem Cell. 2020 07 02; 27(1):147-157.e7. PMID: 32413331.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  7. Papúchová H, Meissner TB, Li Q, Strominger JL, Tilburgs T. The Dual Role of HLA-C in Tolerance and Immunity at the Maternal-Fetal Interface. Front Immunol. 2019; 10:2730. PMID: 31921098; PMCID: PMC6913657.
    Citations: 28     Fields:    Translation:HumansCells
  8. Chen Z, Yu H, Shi X, Warren CR, Lotta LA, Friesen M, Meissner TB, Langenberg C, Wabitsch M, Wareham N, Benson MD, Gerszten RE, Cowan CA. Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes. Circ Res. 2020 01 31; 126(3):330-346. PMID: 31739742.
    Citations: 14     Fields:    Translation:HumansCells
  9. Han X, Wang M, Duan S, Franco PJ, Kenty JH, Hedrick P, Xia Y, Allen A, Ferreira LMR, Strominger JL, Melton DA, Meissner TB, Cowan CA. Generation of hypoimmunogenic human pluripotent stem cells. Proc Natl Acad Sci U S A. 2019 05 21; 116(21):10441-10446. PMID: 31040209; PMCID: PMC6535035.
    Citations: 70     Fields:    Translation:HumansCells
  10. Lang J, Cheng Y, Rolfe A, Hammack C, Vera D, Kyle K, Wang J, Meissner TB, Ren Y, Cowan C, Tang H. An hPSC-Derived Tissue-Resident Macrophage Model Reveals Differential Responses of Macrophages to ZIKV and DENV Infection. Stem Cell Reports. 2018 08 14; 11(2):348-362. PMID: 29983385.
    Citations: 9     Fields:    Translation:HumansCells
  11. Tilburgs T, Meissner TB, Ferreira LMR, Mulder A, Musunuru K, Ye J, Strominger JL. NLRP2 is a suppressor of NF-?B signaling and HLA-C expression in human trophoblasts†,‡. Biol Reprod. 2017 Apr 01; 96(4):831-842. PMID: 28340094; PMCID: PMC5803763.
    Citations: 22     Fields:    Translation:HumansCells
  12. Ferreira LMR, Meissner TB, Tilburgs T, Strominger JL. HLA-G: At the Interface of Maternal-Fetal Tolerance. Trends Immunol. 2017 04; 38(4):272-286. PMID: 28279591.
    Citations: 82     Fields:    Translation:HumansAnimalsCells
  13. Yoshihama S, Roszik J, Downs I, Meissner TB, Vijayan S, Chapuy B, Sidiq T, Shipp MA, Lizee GA, Kobayashi KS. NLRC5/MHC class I transactivator is a target for immune evasion in cancer. Proc Natl Acad Sci U S A. 2016 May 24; 113(21):5999-6004. PMID: 27162338; PMCID: PMC4889388.
    Citations: 89     Fields:    Translation:HumansCells
  14. Ferreira LM, Meissner TB, Mikkelsen TS, Mallard W, O'Donnell CW, Tilburgs T, Gomes HA, Camahort R, Sherwood RI, Gifford DK, Rinn JL, Cowan CA, Strominger JL. A distant trophoblast-specific enhancer controls HLA-G expression at the maternal-fetal interface. Proc Natl Acad Sci U S A. 2016 May 10; 113(19):5364-9. PMID: 27078102; PMCID: PMC4868469.
    Citations: 39     Fields:    Translation:HumansCells
  15. Gupta RM, Meissner TB, Cowan CA, Musunuru K. Genome-Edited Human Pluripotent Stem Cell-Derived Macrophages as a Model of Reverse Cholesterol Transport--Brief Report. Arterioscler Thromb Vasc Biol. 2016 Jan; 36(1):15-8. PMID: 26543098; PMCID: PMC4690765.
    Citations: 17     Fields:    Translation:HumansCells
  16. Kim HJ, Barnitz RA, Kreslavsky T, Brown FD, Moffett H, Lemieux ME, Kaygusuz Y, Meissner T, Holderried TA, Chan S, Kastner P, Haining WN, Cantor H. Stable inhibitory activity of regulatory T cells requires the transcription factor Helios. Science. 2015 Oct 16; 350(6258):334-9. PMID: 26472910; PMCID: PMC4627635.
    Citations: 165     Fields:    Translation:AnimalsCells
  17. Mandal PK, Ferreira LM, Collins R, Meissner TB, Boutwell CL, Friesen M, Vrbanac V, Garrison BS, Stortchevoi A, Bryder D, Musunuru K, Brand H, Tager AM, Allen TM, Talkowski ME, Rossi DJ, Cowan CA. Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9. Cell Stem Cell. 2014 Nov 06; 15(5):643-52. PMID: 25517468.
    Citations: 207     Fields:    Translation:HumansAnimalsCells
  18. Meissner TB, Mandal PK, Ferreira LM, Rossi DJ, Cowan CA. Genome editing for human gene therapy. Methods Enzymol. 2014; 546:273-95. PMID: 25398345.
    Citations: 7     Fields:    Translation:HumansCells
  19. Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, Schinzel RT, Xia F, Tang A, Xia Y, Figueroa E, Wann A, Ahfeldt T, Daheron L, Zhang F, Rubin LL, Peng LF, Chung RT, Musunuru K, Cowan CA. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell. 2013 Feb 07; 12(2):238-51. PMID: 23246482.
    Citations: 235     Fields:    Translation:HumansCells
  20. Biswas A, Meissner TB, Kawai T, Kobayashi KS. Cutting edge: impaired MHC class I expression in mice deficient for Nlrc5/class I transactivator. J Immunol. 2012 Jul 15; 189(2):516-20. PMID: 22711889; PMCID: PMC3578426.
    Citations: 47     Fields:    Translation:AnimalsCells
  21. Meissner TB, Liu YJ, Lee KH, Li A, Biswas A, van Eggermond MC, van den Elsen PJ, Kobayashi KS. NLRC5 cooperates with the RFX transcription factor complex to induce MHC class I gene expression. J Immunol. 2012 May 15; 188(10):4951-8. PMID: 22490869; PMCID: PMC3345046.
    Citations: 67     Fields:    Translation:HumansCells
  22. Meissner TB, Li A, Liu YJ, Gagnon E, Kobayashi KS. The nucleotide-binding domain of NLRC5 is critical for nuclear import and transactivation activity. Biochem Biophys Res Commun. 2012 Feb 24; 418(4):786-91. PMID: 22310711.
    Citations: 31     Fields:    Translation:HumansCells
  23. Meissner TB, Li A, Kobayashi KS. NLRC5: a newly discovered MHC class I transactivator (CITA). Microbes Infect. 2012 Jun; 14(6):477-84. PMID: 22209772.
    Citations: 35     Fields:    Translation:HumansAnimals
  24. Meissner TB, Li A, Biswas A, Lee KH, Liu YJ, Bayir E, Iliopoulos D, van den Elsen PJ, Kobayashi KS. NLR family member NLRC5 is a transcriptional regulator of MHC class I genes. Proc Natl Acad Sci U S A. 2010 Aug 03; 107(31):13794-9. PMID: 20639463.
    Citations: 177     Fields:    Translation:HumansCells
  25. Meissner T, Krause E, Lödige I, Vinkemeier U. Arginine methylation of STAT1: a reassessment. Cell. 2004 Nov 24; 119(5):587-9; discussion 589-590. PMID: 15550240.
    Citations: 18     Fields:    Translation:HumansCells
  26. Meissner T, Krause E, Vinkemeier U. Ratjadone and leptomycin B block CRM1-dependent nuclear export by identical mechanisms. FEBS Lett. 2004 Oct 08; 576(1-2):27-30. PMID: 15474004.
    Citations: 32     Fields:    Translation:HumansCells
  27. Marg A, Shan Y, Meyer T, Meissner T, Brandenburg M, Vinkemeier U. Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1. J Cell Biol. 2004 Jun 21; 165(6):823-33. PMID: 15210729; PMCID: PMC2172394.
    Citations: 67     Fields:    Translation:HumansAnimalsCells
  28. Josten F, Fuss B, Feix M, Meissner T, Hoch M. Cooperation of JAK/STAT and Notch signaling in the Drosophila foregut. Dev Biol. 2004 Mar 01; 267(1):181-9. PMID: 14975725.
    Citations: 9     Fields:    Translation:AnimalsCells
  29. Fuss B, Meissner T, Bauer R, Lehmann C, Eckardt F, Hoch M. Control of endoreduplication domains in the Drosophila gut by the knirps and knirps-related genes. Mech Dev. 2001 Jan; 100(1):15-23. PMID: 11118880.
    Citations: 7     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.