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Louis Martens Kunkel, Ph.D.

Other Positions

Evaluating a New Antibody for SP Cell Sorting/Differentiation Capacity of SP Cells Co-Cultured with DRGs
Summer, 05/01/02 - 08/31/02

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R41AR074832 (KUNKEL, LOUIS M) Sep 4, 2018 - Aug 31, 2019
    Genome-wide CRISPR screen to identify pro-myogenic factors for cell therapy of DMD
    Role: Principal Investigator
  2. U54HD090255 (POMEROY, SCOTT LOREN) Sep 23, 2016 - May 31, 2021
    Boston Intellectual and Developmental Disabilities Research Center
    Role: Co-Principal Investigator
  3. R01AR064300 (KUNKEL, LOUIS M) Apr 1, 2014 - Jul 31, 2024
    Modulation of Jagged1/Pitpna in DMD as a means of therapy
    Role: Principal Investigator
  4. U54HD060848 (EMERSON, CHARLES P.) Sep 10, 2008 - May 31, 2018
    Biomarkers for Therapy of FSHD (U54)
    Role: Co-Principal Investigator
  5. R01DK081647 (KUNKEL, LOUIS M) Aug 1, 2008 - Jul 31, 2013
    Genetic Studies of Interstitial Cystitis
    Role: Co-Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bruels CC, Littel HR, Daugherty AL, Stafki S, Estrella EA, McGaughy ES, Truong D, Badalamenti JP, Pais L, Ganesh VS, O'Donnell-Luria A, Stalker HJ, Wang Y, Collins C, Behlmann A, Lemmers RJLF, van der Maarel SM, Laine R, Ghosh PS, Darras BT, Zingariello CD, Pacak CA, Kunkel LM, Kang PB. Diagnostic capabilities of nanopore long-read sequencing in muscular dystrophy. Ann Clin Transl Neurol. 2022 08; 9(8):1302-1309. PMID: 35734998; PMCID: PMC9380148.
    Citations:    Fields:    
  2. Wang R, Kumar B, Doud EH, Mosley AL, Alexander MS, Kunkel LM, Nakshatri H. Skeletal muscle-specific overexpression of miR-486 limits mammary tumor-induced skeletal muscle functional limitations. Mol Ther Nucleic Acids. 2022 Jun 14; 28:231-248. PMID: 35402076; PMCID: PMC8971682.
  3. Alexander MS, Hightower RM, Reid AL, Bennett AH, Iyer L, Slonim DK, Saha M, Kawahara G, Kunkel LM, Kopin AS, Gupta VA, Kang PB, Draper I. hnRNP L is essential for myogenic differentiation and modulates myotonic dystrophy pathologies. Muscle Nerve. 2021 06; 63(6):928-940. PMID: 33651408; PMCID: PMC8131270.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  4. Oláhová M, Peter B, Szilagyi Z, Diaz-Maldonado H, Singh M, Sommerville EW, Blakely EL, Collier JJ, Hoberg E, Stránecký V, Hartmannová H, Bleyer AJ, McBride KL, Bowden SA, Korandová Z, Pecinová A, Ropers HH, Kahrizi K, Najmabadi H, Tarnopolsky MA, Brady LI, Weaver KN, Prada CE, Õunap K, Wojcik MH, Pajusalu S, Syeda SB, Pais L, Estrella EA, Bruels CC, Kunkel LM, Kang PB, Bonnen PE, Mrácek T, Kmoch S, Gorman GS, Falkenberg M, Gustafsson CM, Taylor RW. POLRMT mutations impair mitochondrial transcription causing neurological disease. Nat Commun. 2021 02 18; 12(1):1135. PMID: 33602924; PMCID: PMC7893070.
    Citations: 2     Fields:    Translation:HumansCells
  5. Lambert MR, Spinazzola JM, Widrick JJ, Pakula A, Conner JR, Chin JE, Owens JM, Kunkel LM. PDE10A Inhibition Reduces the Manifestation of Pathology in DMD Zebrafish and Represses the Genetic Modifier PITPNA. Mol Ther. 2021 03 03; 29(3):1086-1101. PMID: 33221436; PMCID: PMC7934586.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  6. Spinazzola JM, Lambert MR, Gibbs DE, Conner JR, Krikorian GL, Pareek P, Rago C, Kunkel LM. Effect of serotonin modulation on dystrophin-deficient zebrafish. Biol Open. 2020 08 28; 9(8). PMID: 32718931.
    Citations: 2     Fields:    Translation:Animals
  7. Lek A, Zhang Y, Woodman KG, Huang S, DeSimone AM, Cohen J, Ho V, Conner J, Mead L, Kodani A, Pakula A, Sanjana N, King OD, Jones PL, Wagner KR, Lek M, Kunkel LM. Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy. Sci Transl Med. 2020 03 25; 12(536). PMID: 32213627.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  8. Spinazzola JM, Lambert MR, Gibbs DE, Conner JR, Krikorian GL, Pareek P, Rago C, Kunkel LM. Effect of serotonin modulation on dystrophin-deficient zebrafish. Biol Open. 2020 Jan 01. PMID: 34004743.
  9. Kunkel LM. To dystrophin and beyond: an interview with Louis Kunkel. Dis Model Mech. 2019 12 12; 13(2). PMID: 31843755; PMCID: PMC6918775.
    Citations: 2     Fields:    Translation:HumansAnimals
  10. Palmer NP, Silvester JA, Lee JJ, Beam AL, Fried I, Valtchinov VI, Rahimov F, Kong SW, Ghodoussipour S, Hood HC, Bousvaros A, Grand RJ, Kunkel LM, Kohane IS. Concordance between gene expression in peripheral whole blood and colonic tissue in children with inflammatory bowel disease. PLoS One. 2019; 14(10):e0222952. PMID: 31618209; PMCID: PMC6795427.
    Citations: 9     Fields:    Translation:Humans
  11. Hightower RM, Reid AL, Gibbs DE, Wang Y, Widrick JJ, Kunkel LM, Kastenschmidt JM, Villalta SA, van Groen T, Chang H, Gornisiewicz S, Landesman Y, Tamir S, Alexander MS. The SINE Compound KPT-350 Blocks Dystrophic Pathologies in DMD Zebrafish and Mice. Mol Ther. 2020 01 08; 28(1):189-201. PMID: 31628052.
    Citations: 10     Fields:    Translation:AnimalsCells
  12. Bruels CC, Li C, Mendoza T, Khan J, Reddy HM, Estrella EA, Ghosh PS, Darras BT, Lidov HGW, Pacak CA, Kunkel LM, Modave F, Draper I, Kang PB. Identification of a pathogenic mutation in ATP2A1 via in silico analysis of exome data for cryptic aberrant splice sites. Mol Genet Genomic Med. 2019 03; 7(3):e552. PMID: 30688039.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  13. Pakula A, Lek A, Widrick J, Mitsuhashi H, Bugda Gwilt KM, Gupta VA, Rahimov F, Criscione J, Zhang Y, Gibbs D, Murphy Q, Manglik A, Mead L, Kunkel L. Transgenic zebrafish model of DUX4 misexpression reveals a developmental role in FSHD pathogenesis. Hum Mol Genet. 2019 01 15; 28(2):320-331. PMID: 30307508; PMCID: PMC6489409.
    Citations: 7     Fields:    Translation:Animals
  14. Widrick JJ, Kawahara G, Alexander MS, Beggs AH, Kun