Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Hooman Mirzakhani, Ph.D., M.D.

Title
Institution
Department
Address
Phone

Biography
2012
MGH Departmental Award-Clinical Research Day
2015 - 2017
NIH LRP-NHLBI Award
2016
Scholar Award-American Federation for Medical Research
2016
Vitamin D Workshop Travel Award
2016
Junior Investigator Award-IAMA
2018
Clinical Science Award-American Lung Association
2018
Scholarship Award-American Thoracic Society
2016
Doctoral Dissertation Fellowship Award
2018 - 2020
NIH LRP-NHLBI Award (Renewal)
2020 - 2022
NIH LRP-NHLBI Award (Renewal)
2021
Department of Medicine's Research Performance Incentive Program Award

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K01HL146977 (MIRZAKHANI, HOOMAN) Jan 3, 2020 - Dec 31, 2024
    NIH
    Integrative Longitudinal Genomics of Maternal Asthma-Preeclampsia Overlap and Risk of Childhood Asthma
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chen YS, Mirzakhani H, Lu M, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Carey VJ, Harshfield BJ, Laranjo N, Litonjua AA, Weiss ST, Lee-Sarwar KA. The Association of Prenatal Vitamin D Sufficiency With Aeroallergen Sensitization and Allergic Rhinitis in Early Childhood. J Allergy Clin Immunol Pract. 2021 Jun 21. PMID: 34166843.
    Citations:    Fields:    
  2. Li J, Tiwari A, Mirzakhani H, Wang AL, Kho AT, McGeachie MJ, Litonjua AA, Weiss ST, Tantisira KG. Circulating MicroRNA: Incident Asthma Prediction and Vitamin D Effect Modification. J Pers Med. 2021 Apr 16; 11(4). PMID: 33923455.
    Citations:    
  3. Brustad N, Greve JH, Mirzakhani H, Pedersen CT, Eliasen AU, Stokholm J, Lasky-Su J, Bønnelykke K, Litonjua AA, Weiss ST, Bisgaard H, Chawes BL. High-dose vitamin D during pregnancy and pathway gene polymorphisms in prevention of offspring persistent wheeze. Pediatr Allergy Immunol. 2021 05; 32(4):679-689. PMID: 33453076.
    Citations:    Fields:    Translation:Humans
  4. McElrath TF, Cantonwine DE, Gray KJ, Mirzakhani H, Doss RC, Khaja N, Khalid M, Page G, Brohman B, Zhang Z, Sarracino D, Rosenblatt KP. Late first trimester circulating microparticle proteins predict the risk of preeclampsia PMID: 33087742.
    Citations:    Fields:    Translation:HumansCells
  5. Jakobi M, Kiefer A, Mirzakhani H, Rauh M, Zimmermann T, Xepapadaki P, Stanic B, Akdis M, Papadopoulos NG, Raby BA, Weiss ST, Finotto S. Role of nuclear factor of activated T cells 2 (NFATc2) in allergic asthma. Immun Inflamm Dis. 2020 12; 8(4):704-712. PMID: 33079489.
    Citations: 2     Fields:    
  6. Yadama AP, Maiorino E, Carey VJ, McElrath TF, Litonjua AA, Loscalzo J, Weiss ST, Mirzakhani H. Early-pregnancy transcriptome signatures of preeclampsia: from peripheral blood to placenta. Sci Rep. 2020 10 12; 10(1):17029. PMID: 33046794.
    Citations: 1     Fields:    Translation:HumansCells
  7. Gray KJ, Kovacheva VP, Mirzakhani H, Bjonnes AC, Almoguera B, Wilson ML, Ingles SA, Lockwood CJ, Hakonarson H, McElrath TF, Murray JC, Norwitz ER, Karumanchi SA, Bateman BT, Keating BJ, Saxena R. Risk of pre-eclampsia in patients with a maternal genetic predisposition to common medical conditions: a case-control study. BJOG. 2021 01; 128(1):55-65. PMID: 32741103.
    Citations: 1     Fields:    Translation:Humans
  8. Mirzakhani H, Weiss ST. Fetal sex and risk of preeclampsia: Dose maternal race matter? J Matern Fetal Neonatal Med. 2020 Sep 13; 1-9. PMID: 32924669.
    Citations: 2     Fields:    
  9. Lu M, Litonjua AA, O'Connor GT, Zeiger RS, Bacharier L, Schatz M, Carey VJ, Weiss ST, Mirzakhani H. Effect of early and late prenatal vitamin D and maternal asthma status on offspring asthma or recurrent wheeze. J Allergy Clin Immunol. 2021 Apr; 147(4):1234-1241.e3. PMID: 32822692.
    Citations: 1     Fields:    
  10. Zarei S, Costas Y, Orozco G, Zaydlin M, Mirtar A, Abouali M, Diaz-Marty C, Akhlaghipour G, Fernandez Altamirano P, Gonzalez Cardona AR, Reiley LE, Mirzakhani H. A Web-Based Pharmacogenomics Search Tool for Precision Medicine in Perioperative Care. J Pers Med. 2020 Jul 21; 10(3). PMID: 32708157.
    Citations: 1     
  11. Mirzakhani H, Kelly RS, Yadama AP, Chu SH, Lasky-Su JA, Litonjua AA, Weiss ST. Stability of developmental status and risk of impairment at 24 and 36 months in late preterm infants. Infant Behav Dev. 2020 08; 60:101462. PMID: 32599336.
    Citations:    Fields:    Translation:Humans
  12. He M, Mirzakhani H, Chen L, Wu R, Litonjua AA, Bacharier L, Weiss ST, Nelson DM. Vitamin D Sufficiency Has a Limited Effect on Placental Structure and Pathology: Placental Phenotypes in the VDAART Trial. Endocrinology. 2020 06 01; 161(6). PMID: 32270179.
    Citations:    Fields:    Translation:Humans
  13. Litonjua AA, Carey VJ, Laranjo N, Stubbs BJ, Mirzakhani H, O'Connor GT, Sandel M, Beigelman A, Bacharier LB, Zeiger RS, Schatz M, Hollis BW, Weiss ST. Six-Year Follow-up of a Trial of Antenatal Vitamin D for Asthma Reduction. N Engl J Med. 2020 02 06; 382(6):525-533. PMID: 32023372.
    Citations: 21     Fields:    Translation:Humans
  14. Yadama AP, Mirzakhani H, McElrath TF, Litonjua AA, Weiss ST. Transcriptome analysis of early pregnancy vitamin D status and spontaneous preterm birth. PLoS One. 2020; 15(1):e0227193. PMID: 31995561.
    Citations: 2     Fields:    Translation:HumansCells
  15. Mirzakhani H, McElrath TF, Weiss ST. Vital Considerations for Aspirin in Prevention of Preeclampsia, a Multifaceted Pregnancy Disorder. JAMA Pediatr. 2020 01 01; 174(1):95. PMID: 31682681.
    Citations: 1     Fields:    Translation:Humans
  16. Koch S, Knipfer L, Kölle J, Mirzakhani H, Graser A, Zimmermann T, Kiefer A, Melichar VO, Rascher W, Papadopoulos NG, Rieker RJ, Raby BA, Weiss ST, Wirtz S, Finotto S. Targeted deletion of NFAT-Interacting-Protein-(NIP) 45 resolves experimental asthma by inhibiting Innate Lymphoid Cells group 2 (ILC2). Sci Rep. 2019 10 30; 9(1):15695. PMID: 31666531.
    Citations:    Fields:    Translation:HumansAnimalsCells
  17. Yadama AP, Kelly RS, Lee-Sarwar K, Mirzakhani H, Chu SH, Kachroo P, Litonjua AA, Lasky-Su J, Weiss ST. Allergic disease and low ASQ communication score in children. Brain Behav Immun. 2020 01; 83:293-297. PMID: 31606476.
    Citations: 3     Fields:    Translation:Humans
  18. Mirzakhani H, Carey VJ, McElrath TF, Hollis BW, O'Connor GT, Zeiger RS, Bacharier L, Litonjua AA, Weiss ST. Maternal Asthma, Preeclampsia, and Risk for Childhood Asthma at Age Six. Am J Respir Crit Care Med. 2019 09 01; 200(5):638-642. PMID: 31059286.
    Citations: 1     Fields:    Translation:Humans
  19. Kachroo P, Kelly RS, Mirzakhani H, Lee-Sarwar K, Chawes BL, Blighe K, Davaasambuu G, Bisgaard H, Litonjua AA, Weiss ST, Lasky-Su J. Fish oil supplementation during pregnancy is protective against asthma/wheeze in offspring. J Allergy Clin Immunol Pract. 2020 01; 8(1):388-391.e2. PMID: 31226448.
    Citations:    Fields:    Translation:Humans
  20. Nozari A, Akeju O, Mirzakhani H, Eskandar E, Ma Z, Hossain MA, Wang Q, Greenblatt DJ, Martyn JAJ. Prolonged therapy with the anticonvulsant carbamazepine leads to increased plasma clearance of fentanyl. J Pharm Pharmacol. 2019 Jun; 71(6):982-987. PMID: 30793320.
    Citations: 2     Fields:    Translation:Humans
  21. Mirzakhani H, Carey VJ, Zeiger R, Bacharier LB, O'Connor GT, Schatz MX, Laranjo N, Weiss ST, Litonjua AA. Impact of parental asthma, prenatal maternal asthma control, and vitamin D status on risk of asthma and recurrent wheeze in 3-year-old children. Clin Exp Allergy. 2019 04; 49(4):419-429. PMID: 30461089.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  22. Mirzakhani H, Carey VJ, McElrath TF, Qiu W, Hollis BW, O'Connor GT, Zeiger RS, Bacharier L, Litonjua AA, Weiss ST. Impact of Preeclampsia on the Relationship between Maternal Asthma and Offspring Asthma. An Observation from the VDAART Clinical Trial. Am J Respir Crit Care Med. 2019 01 01; 199(1):32-42. PMID: 30153046.
    Citations: 4     Fields:    Translation:Humans
  23. Mirzakhani, H, Weiss, ST. Folic Acid and Preeclampsia: Is There an Invisible Accomplice? The BMJ, December. 2018. View Publication.
  24. Mirzakhani, H,Weiss, ST . Mendelian Randomization of Vitamin D for Preeclampsia: Embracing Complexity of Inference. The BMJ, September. 2018. View Publication.
  25. Mirzakhani H, Al-Garawi AA, Carey VJ, Qiu W, Litonjua AA, Weiss ST. Expression network analysis reveals cord blood vitamin D-associated genes affecting risk of early life wheeze. Thorax. 2019 02; 74(2):200-202. PMID: 30021811.
    Citations: 1     Fields:    Translation:Humans
  26. Gray KJ, Kovacheva VP, Mirzakhani H, Bjonnes AC, Almoguera B, DeWan AT, Triche EW, Saftlas AF, Hoh J, Bodian DL, Klein E, Huddleston KC, Ingles SA, Lockwood CJ, Hakonarson H, McElrath TF, Murray JC, Wilson ML, Norwitz ER, Karumanchi SA, Bateman BT, Keating BJ, Saxena R. Gene-Centric Analysis of Preeclampsia Identifies Maternal Association at PLEKHG1. Hypertension. 2018 08; 72(2):408-416. PMID: 29967039.
    Citations: 10     Fields:    Translation:Humans
  27. Mirzakhani H, Weiss ST, Litonjua AA. Reply. J Allergy Clin Immunol. 2018 02; 141(2):829-830. PMID: 29169707.
    Citations:    Fields:    Translation:Humans
  28. Mirzakhani H, De Vivo I, Leeder JS, Gaedigk R, Vyhlidal CA, Weiss ST, Tantisira K. Early pregnancy intrauterine fetal exposure to maternal smoking and impact on fetal telomere length. Eur J Obstet Gynecol Reprod Biol. 2017 Nov; 218:27-32. PMID: 28926727.
    Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
  29. Mirzakhani H, Carey VJ, McElrath TF, Laranjo N, O'Connor G, Iverson RE, Lee-Parritz A, Strunk RC, Bacharier LB, Macones GA, Zeiger RS, Schatz M, Hollis BW, Litonjua AA, Weiss ST. The Association of Maternal Asthma and Early Pregnancy Vitamin D with Risk of Preeclampsia: An Observation From Vitamin D Antenatal Asthma Reduction Trial (VDAART). J Allergy Clin Immunol Pract. 2018 Mar - Apr; 6(2):600-608.e2. PMID: 28923490.
    Citations: 8     Fields:    Translation:Humans
  30. Blighe K, Chawes BL, Kelly RS, Mirzakhani H, McGeachie M, Litonjua AA, Weiss ST, Lasky-Su JA. Vitamin D prenatal programming of childhood metabolomics profiles at age 3 y. Am J Clin Nutr. 2017 Oct; 106(4):1092-1099. PMID: 28835366.
    Citations: 18     Fields:    Translation:Humans
  31. Kelly RS, Giorgio RT, Chawes BL, Palacios NI, Gray KJ, Mirzakhani H, Wu A, Blighe K, Weiss ST, Lasky-Su J. Applications of Metabolomics in the Study and Management of Preeclampsia; A Review of the Literature. Metabolomics. 2017 07; 13(7). PMID: 30473646.
    Citations: 10     Fields:    
  32. Mirzakhani H, O'Connor G, Bacharier LB, Zeiger RS, Schatz MX, Weiss ST, Litonjua AA. Asthma control status in pregnancy, body mass index, and maternal vitamin D levels. J Allergy Clin Immunol. 2017 11; 140(5):1453-1456.e7. PMID: 28606587.
    Citations: 7     Fields:    Translation:Humans
  33. Mirzakhani H, Eikermann M, Bittner E, Nozari A. In Response. Anesth Analg. 2017 04; 124(4):1371-1372. PMID: 28319553.
    Citations:    Fields:    
  34. Mirzakhani H, Eikermann M, Bittner E, Nozari A. In Response: Effective Doses of Neuromuscular Blockers During Electroconvulsive Therapy and the Effect of ECT Parameters. Anesth Analg. 2017 Feb 16. PMID: 28212216.
    Citations:    Fields:    
  35. Kelly RS, Croteau-Chonka DC, Dahlin A, Mirzakhani H, Wu AC, Wan ES, McGeachie MJ, Qiu W, Sordillo JE, Al-Garawi A, Gray KJ, McElrath TF, Carey VJ, Clish CB, Litonjua AA, Weiss ST, Lasky-Su JA. Integration of metabolomic and transcriptomic networks in pregnant women reveals biological pathways and predictive signatures associated with preeclampsia. Metabolomics. 2017 Jan; 13(1). PMID: 28596717.
    Citations: 16     Fields:    
  36. Mirzakhani H, Litonjua AA, McElrath TF, O'Connor G, Lee-Parritz A, Iverson R, Macones G, Strunk RC, Bacharier LB, Zeiger R, Hollis BW, Handy DE, Sharma A, Laranjo N, Carey V, Qiu W, Santolini M, Liu S, Chhabra D, Enquobahrie DA, Williams MA, Loscalzo J, Weiss ST. Early pregnancy vitamin D status and risk of preeclampsia. J Clin Invest. 2016 12 01; 126(12):4702-4715. PMID: 27841759.
    Citations: 35     Fields:    Translation:Humans
  37. Mirzakhani H, Nozari A. In Response. Anesth Analg. 2016 11; 123(5):1329-1330. PMID: 27551738.
    Citations:    Fields:    
  38. Al-Garawi A, Carey VJ, Chhabra D, Mirzakhani H, Morrow J, Lasky-Su J, Qiu W, Laranjo N, Litonjua AA, Weiss ST. The Role of Vitamin D in the Transcriptional Program of Human Pregnancy. PLoS One. 2016; 11(10):e0163832. PMID: 27711190.
    Citations: 11     Fields:    Translation:HumansCells
  39. Mirzakhani H, Bittner E, Eikermann M, Nozari A. In Response. Anesth Analg. 2016 10; 123(4):1060-1. PMID: 27636580.
    Citations:    Fields:    
  40. Sigakis MJ, Leffert LR, Mirzakhani H, Sharawi N, Rajala B, Callaghan WM, Kuklina EV, Creanga AA, Mhyre JM, Bateman BT. The Validity of Discharge Billing Codes Reflecting Severe Maternal Morbidity. Anesth Analg. 2016 09; 123(3):731-8. PMID: 27387839.
    Citations: 5     Fields:    Translation:Humans
  41. Mirzakhani H, Guchelaar HJ, Welch CA, Cusin C, Doran ME, MacDonald TO, Bittner EA, Eikermann M, Nozari A. Minimum Effective Doses of Succinylcholine and Rocuronium During Electroconvulsive Therapy: A Prospective, Randomized, Crossover Trial. Anesth Analg. 2016 09; 123(3):587-96. PMID: 26967896.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  42. Koch S, Graser A, Mirzakhani H, Zimmermann T, Melichar VO, Wölfel M, Croteau-Chonka DC, Raby BA, Weiss ST, Finotto S. Increased expression of nuclear factor of activated T cells 1 drives IL-9-mediated allergic asthma. J Allergy Clin Immunol. 2016 06; 137(6):1898-1902.e7. PMID: 26993036.
    Citations: 5     Fields:    Translation:Humans
  43. Mirzakhani, H. The Role of Clinical Pharmacology and Pharmacogenetics in Electroconvulsive Therapy: From Safety to Efficacy (Doctoral Dissertation). Leiden University Medical Center, Leiden University, The Netherlands (ISBN 9789492026088). 2016. View Publication.
  44. Mirzakhani H, van Dormolen J, van der Weide K, Guchelaar HJ, van Noorden MS, Swen J. Aberrant CYP2D6 metabolizer phenotypes do not show increased frequency in patients undergoing ECT after antidepressant therapy. Pharmacogenet Genomics. 2015 Oct; 25(10):515-7. PMID: 26230381.
    Citations:    Fields:    Translation:Humans
  45. Mirzakhani H, van Noorden MS, Swen J, Nozari A, Guchelaar HJ. Pharmacogenetics in electroconvulsive therapy and adjunctive medications. Pharmacogenomics. 2015; 16(9):1015-31. PMID: 26115083.
    Citations:    Fields:    Translation:Humans
  46. Mirzakhani, H . Impact of Vitamin D and Asthma on Preeclampsia: A Sequential Evidence-Based Approach to Genomic Analysis (Master's Thesis). Harvard Medical School, Boston, MA, USA. 2015.
  47. Mirzakhani H, Al-Garawi A, Weiss ST, Litonjua AA. Vitamin D and the development of allergic disease: how important is it? Clin Exp Allergy. 2015 Jan; 45(1):114-25. PMID: 25307157.
    Citations: 36     Fields:    Translation:Humans
  48. Kamran Hejazi Kenari S, Mirzakhani H, Eslami M, Saidi RF. Current state of the art in management of vascular complications after pediatric liver transplantation. Pediatr Transplant. 2015 Feb; 19(1):18-26. PMID: 25425338.
    Citations: 2     Fields:    Translation:Humans
  49. Kamran Hejazi Kenari S, Mirzakhani H, Saidi RF. Pediatric transplantation and tolerance: past, present, and future. Pediatr Transplant. 2014 Aug; 18(5):435-45. PMID: 24931282.
    Citations: 3     Fields:    Translation:HumansCells
  50. Mirzakhani H, Williams JN, Mello J, Joseph S, Meyer MJ, Waak K, Schmidt U, Kelly E, Eikermann M. Muscle weakness predicts pharyngeal dysfunction and symptomatic aspiration in long-term ventilated patients. Anesthesiology. 2013 Aug; 119(2):389-97. PMID: 23584384.
    Citations: 22     Fields:    Translation:Humans
  51. Mirzakhani H, Nozari A, Ehrenfeld JM, Peterfreund R, Szabo M, Walsh JL, Jiang Y, Sandberg W, Rosow C, Wang J. Case report: profound hypotension after anesthetic induction with propofol in patients treated with rifampin. Anesth Analg. 2013 Jul; 117(1):61-4. PMID: 23687230.
    Citations:    Fields:    Translation:Humans
  52. Mirzakhani H, Eikermann M. Train-of-four recovery does not indicate optimal recovery of the margin of safety of neuromuscular transmission. Eur J Anaesthesiol. 2013 Jan; 30(1):40-1. PMID: 22801583.
    Citations:    Fields:    Translation:Humans
  53. Edward Bittner, Arielle Butterly, Hooman Mirzakhani, Abhishek Jayadevappa, Theresa MacDonald, Edward George, Ulrich Schmidt, Matthias Eikermann . Severe postoperative hemodynamic events after spinal anesthesia a prospective observational study. Journal of Anesthesiology & Clinical Science. 2012; 14(1):1-8. View Publication.
  54. Mirzakhani H, Welch CA, Eikermann M, Nozari A. Neuromuscular blocking agents for electroconvulsive therapy: a systematic review. Acta Anaesthesiol Scand. 2012 Jan; 56(1):3-16. PMID: 22092267.
    Citations: 11     Fields:    Translation:Humans
  55. Mirzakhani, H. and Nozari. Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood. Ischemia. 2011; Ch10:145-58. View Publication.
  56. Mirzakhani, H. Computer in Plastic Surgery (Doctoral Dissertation). Tehran University of Medical Sciences, Tehran, Iran. 1997.
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Mirzakhani's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (195)
Explore
_
Co-Authors (39)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.