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Jason Comander, M.D., Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Pennesi ME, Yang P, Birch DG, Weng CY, Moore AT, Iannaccone A, Comander JI, Jayasundera T, Chulay J. Intravitreal Delivery of rAAV2tYF-CB-hRS1 Vector for Gene Augmentation Therapy in Patients with X-Linked Retinoschisis: 1-Year Clinical Results. Ophthalmol Retina. 2022 12; 6(12):1130-1144. PMID: 35781068.
    Citations:    Fields:    
  2. Aleman TS, Huckfeldt RM, Serrano LW, Pearson DJ, Vergilio GK, McCague S, Marshall KA, Ashtari M, Doan TM, Weigel-DiFranco CA, Biron BS, Wen XH, Chung DC, Liu E, Ferenchak K, Morgan JIW, Pierce EA, Eliott D, Bennett J, Comander J, Maguire AM. Adeno-Associated Virus Serotype 2-hCHM Subretinal Delivery to the Macula in Choroideremia: Two-Year Interim Results of an Ongoing Phase I/II Gene Therapy Trial. Ophthalmology. 2022 10; 129(10):1177-1191. PMID: 35714735.
    Citations:    Fields:    
  3. Rudnick ND, Kim LA, Comander J. Adeno-associated Viral Vectors in the Retina: Delivering Gene Therapy to the Right Destination. Int Ophthalmol Clin. 2022 Apr 01; 62(2):215-229. PMID: 35325920.
    Citations:    Fields:    Translation:Humans
  4. Wang JC, Qian CX, Comander JI. Repair of Rhegmatogenous Retinal Detachment in Choroideremia Secondary to Posterior Extramacular Retinal Hole. Ophthalmic Surg Lasers Imaging Retina. 2022 04; 53(4):182-184. PMID: 35417295.
    Citations:    Fields:    Translation:Humans
  5. Catomeris AJ, Ballios BG, Sangermano R, Wagner NE, Comander JI, Pierce EA, Place EM, Bujakowska KM, Huckfeldt RM. Novel RCBTB1 variants causing later-onset non-syndromic retinal dystrophy with macular chorioretinal atrophy. Ophthalmic Genet. 2022 06; 43(3):332-339. PMID: 35057699; PMCID: PMC9177531.
    Citations:    Fields:    Translation:Humans
  6. Ballios BG, Place EM, Martinez-Velazquez L, Pierce EA, Comander JI, Huckfeldt RM. Beyond Sector Retinitis Pigmentosa: Expanding the Phenotype and Natural History of the Rhodopsin Gene Codon 106 Mutation (Gly-to-Arg) in Autosomal Dominant Retinitis Pigmentosa. Genes (Basel). 2021 11 23; 12(12). PMID: 34946802; PMCID: PMC8701931.
    Citations:    Fields:    Translation:Humans
  7. Bujakowska KM, Comander J. Moving Towards PDE6A Gene Supplementation Therapy. JAMA Ophthalmol. 2020 12 01; 138(12):1251-1252. PMID: 33057571; PMCID: PMC8168273.
    Citations:    Fields:    Translation:Humans
  8. Huckfeldt RM, Grigorian F, Place E, Comander JI, Vavvas D, Young LH, Yang P, Shurygina M, Pierce EA, Pennesi ME. Biallelic RP1-associated retinal dystrophies: Expanding the mutational and clinical spectrum. Mol Vis. 2020; 26:423-433. PMID: 32565670.
    Citations: 2     Fields:    Translation:Humans
  9. Zampaglione E, Kinde B, Place EM, Navarro-Gomez D, Maher M, Jamshidi F, Nassiri S, Mazzone JA, Finn C, Schlegel D, Comander J, Pierce EA, Bujakowska KM. Copy-number variation contributes 9% of pathogenicity in the inherited retinal degenerations. Genet Med. 2020 06; 22(6):1079-1087. PMID: 32037395; PMCID: PMC7272325.
    Citations: 25     Fields:    Translation:Humans
  10. Levy JM, Yeh WH, Pendse N, Davis JR, Hennessey E, Butcher R, Koblan LW, Comander J, Liu Q, Liu DR. Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses. Nat Biomed Eng. 2020 01; 4(1):97-110. PMID: 31937940; PMCID: PMC6980783.
    Citations: 100     Fields:    Translation:HumansAnimalsCells
  11. Wan A, Place E, Pierce EA, Comander J. Characterizing variants of unknown significance in rhodopsin: A functional genomics approach. Hum Mutat. 2019 08; 40(8):1127-1144. PMID: 30977563.
    Citations: 3     Fields:    Translation:HumansCells
  12. Terrell D, Comander J. Current Stem-Cell Approaches for the Treatment of Inherited Retinal Degenerations. Semin Ophthalmol. 2019; 34(4):287-292. PMID: 31188052.
    Citations: 10     Fields:    Translation:HumansCells
  13. Stanwyck LK, Place EM, Comander J, Huckfeldt RM, Sobrin L. Predictive value of genetic testing for inherited retinal diseases in patients with suspected atypical autoimmune retinopathy. Am J Ophthalmol Case Rep. 2019 Sep; 15:100461. PMID: 31193260; PMCID: PMC6523031.
    Citations: 2     
  14. Lee Kim E, Weiner AJ, Ung C, Roh M, Wang J, Lee IJ, Huang NT, Stem M, Dahrouj M, Eliott D, Vavvas DG, Young LHY, Williams GA, Garretson BR, Kim IK, Hassan TS, Mukai S, Ruby AJ, Faia LJ, Capone A, Comander J, Kim LA, Wu DM, Drenser KA, Woodward MA, Wolfe JD, Yonekawa Y. Characterization of Epiretinal Proliferation in Full-Thickness Macular Holes and Effects on Surgical Outcomes. Ophthalmol Retina. 2019 08; 3(8):694-702. PMID: 31104985; PMCID: PMC6684822.
    Citations: 3     Fields:    Translation:Humans
  15. Davoudi S, Sevgi DD, Yasa C, Laíns I, Ebrahimiadib N, Roohipoor R, Papavasilieou E, Comander J, Sobrin L. High Reliability of Cone Cell Measurements With Adaptive Optics Scanning Laser Ophthalmoscopy in a Simulated Real-Life Clinical Setting. Ophthalmic Surg Lasers Imaging Retina. 2018 04 01; 49(4):228-235. PMID: 29664978.
    Citations: 2     Fields:    Translation:HumansCells
  16. Carvalho LS, Xiao R, Wassmer SJ, Langsdorf A, Zinn E, Pacouret S, Shah S, Comander JI, Kim LA, Lim L, Vandenberghe LH. Synthetic Adeno-Associated Viral Vector Efficiently Targets Mouse and Nonhuman Primate Retina In Vivo. Hum Gene Ther. 2018 07; 29(7):771-784. PMID: 29325457; PMCID: PMC6066192.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  17. Men CJ, Bujakowska KM, Comander J, Place E, Bedoukian EC, Zhu X, Leroy BP, Fulton AB, Pierce EA. The importance of genetic testing as demonstrated by two cases of CACNA1F-associated retinal generation misdiagnosed as LCA. Mol Vis. 2017; 23:695-706. PMID: 29062221; PMCID: PMC5640518.
    Citations: 5     Fields:    Translation:Humans
  18. Comander J, Weigel-DiFranco C, Maher M, Place E, Wan A, Harper S, Sandberg MA, Navarro-Gomez D, Pierce EA. The Genetic Basis of Pericentral Retinitis Pigmentosa-A Form of Mild Retinitis Pigmentosa. Genes (Basel). 2017 Oct 05; 8(10). PMID: 28981474.
    Citations: 16     Fields:    
  19. Davoudi S, Ebrahimiadib N, Yasa C, Sevgi DD, Roohipoor R, Papavasilieou E, Comander J, Sobrin L. Reply. Am J Ophthalmol. 2017 11; 183:166-167. PMID: 28947061.
    Citations:    Fields:    Translation:Humans
  20. Sevgi DD, Davoudi S, Comander J, Sobrin L. Retinal pigmentary changes in chronic uveitis mimicking retinitis pigmentosa. Graefes Arch Clin Exp Ophthalmol. 2017 Sep; 255(9):1801-1810. PMID: 28523457.
    Citations: 4     Fields:    Translation:Humans
  21. Davoudi S, Ebrahimiadib N, Yasa C, Sevgi DD, Roohipoor R, Papavasilieou E, Comander J, Sobrin L. Outcomes in Autoimmune Retinopathy Patients Treated With Rituximab. Am J Ophthalmol. 2017 Aug; 180:124-132. PMID: 28483493.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  22. Huckfeldt RM, Comander J. Management of Cystoid Macular Edema in Retinitis Pigmentosa. Semin Ophthalmol. 2017; 32(1):43-51. PMID: 27748628.
    Citations: 7     Fields:    Translation:Humans
  23. Davoudi S, Navarro-Gomez D, Shen L, Ung C, Ren A, Sullivan L, Kwong M, Janessian M, Comander J, Gai X, Lobo AM, Papaliodis GN, Sobrin L. NOD2 genetic variants and sarcoidosis-associated uveitis. Am J Ophthalmol Case Rep. 2016 Oct; 3:39-42. PMID: 29503906; PMCID: PMC5757392.
    Citations: 2     
  24. Hafler BP, Comander J, Weigel DiFranco C, Place EM, Pierce EA. Course of Ocular Function in PRPF31 Retinitis Pigmentosa. Semin Ophthalmol. 2016; 31(1-2):49-52. PMID: 26959129; PMCID: PMC6377939.
    Citations: 10     Fields:    Translation:HumansCells
  25. Bujakowska KM, White J, Place E, Consugar M, Comander J. Efficient In Silico Identification of a Common Insertion in the MAK Gene which Causes Retinitis Pigmentosa. PLoS One. 2015; 10(11):e0142614. PMID: 26558903; PMCID: PMC4641726.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  26. Comander J, Weigel-DiFranco C, Sandberg MA, Berson EL. Visual Function in Carriers of X-Linked Retinitis Pigmentosa. Ophthalmology. 2015 Sep; 122(9):1899-906. PMID: 26143542; PMCID: PMC4562908.
    Citations: 21     Fields:    Translation:Humans
  27. Mantopoulos D, Murakami Y, Comander J, Thanos A, Roh M, Miller JW, Vavvas DG. Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment. PLoS One. 2011; 6(9):e24245. PMID: 21961034.
    Citations: 44     Fields:    Translation:AnimalsCells
  28. Comander J, Loewenstein J, Sobrin L. Diagnostic testing and disease monitoring in birdshot chorioretinopathy. Semin Ophthalmol. 2011 Jul-Sep; 26(4-5):329-36. PMID: 21958183.
    Citations: 17     Fields:    Translation:Humans
  29. Comander J, Gardiner M, Loewenstein J. High-resolution optical coherence tomography findings in solar maculopathy and the differential diagnosis of outer retinal holes. Am J Ophthalmol. 2011 Sep; 152(3):413-419.e6. PMID: 21708377.
    Citations: 16     Fields:    Translation:HumansPHPublic Health
  30. Comander J, Pineda R. Accommodating intraocular lenses: theory and practice. Int Ophthalmol Clin. 2010; 50(1):107-17. PMID: 20057300.
    Citations: 1     Fields:    Translation:Humans
  31. Comander J, Natarajan S, Gimbrone MA, García-Cardeña G. Improving the statistical detection of regulated genes from microarray data using intensity-based variance estimation. BMC Genomics. 2004 Feb 27; 5(1):17. PMID: 15113402.
    Citations: 10     Fields:    Translation:Cells
  32. Takayama K, García-Cardena G, Sukhova GK, Comander J, Gimbrone MA, Libby P. Prostaglandin E2 suppresses chemokine production in human macrophages through the EP4 receptor. J Biol Chem. 2002 Nov 15; 277(46):44147-54. PMID: 12215436.
    Citations: 97     Fields:    Translation:HumansCells
  33. García-Cardeña G, Comander JI, Blackman BR, Anderson KR, Gimbrone MA. Mechanosensitive endothelial gene expression profiles: scripts for the role of hemodynamics in atherogenesis? Ann N Y Acad Sci. 2001 Dec; 947:1-6. PMID: 11795257.
    Citations: 20     Fields:    Translation:Cells
  34. Comander J, Weber GM, Gimbrone MA, García-Cardeña G. Argus--a new database system for Web-based analysis of multiple microarray data sets. Genome Res. 2001 Sep; 11(9):1603-10. PMID: 11544205; PMCID: PMC311087.
    Citations: 5     Fields:    
  35. Garcia-Cardeña G, Comander J, Anderson KR, Blackman BR, Gimbrone MA. Biomechanical activation of vascular endothelium as a determinant of its functional phenotype. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4478-85. PMID: 11296290; PMCID: PMC31860.
    Citations: 147     Fields:    Translation:HumansCells
  36. Aach J, Bulyk ML, Church GM, Comander J, Derti A, Shendure J. Computational comparison of two draft sequences of the human genome. Nature. 2001 Feb 15; 409(6822):856-9. PMID: 11237010.
    Citations: 17     Fields:    Translation:HumansCells
  37. Sasoh M, Parel JM, Manns F, Nose I, Comander J, Smiddy WE. Quantification of holmium: YAG and thulium: YAG laser-induced scleral shrinkage for buckling procedures. Ophthalmic Surg Lasers. 1998 May; 29(5):410-21. PMID: 9599366.
    Citations:    Fields:    Translation:Humans
  38. Robinson DS, Parel JM, Denham DB, González-Cirre X, Manns F, Milne PJ, Schachner RD, Herron AJ, Comander J, Hauptmann G. Interstitial laser hyperthermia model development for minimally invasive therapy of breast carcinoma. J Am Coll Surg. 1998 Mar; 186(3):284-92. PMID: 9510259.
    Citations: 11     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.