Harvard Catalyst Profiles

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Laurie Joy Goodyear, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01AG055135 (GOODYEAR, LAURIE J) Dec 15, 2016 - Nov 30, 2022
    NIH
    Animal Studies Investigating Molecular Transducers of Physical Activity
    Role: Principal Investigator
  2. R01DK112283 (GOODYEAR, LAURIE J) Sep 16, 2016 - Jul 31, 2020
    NIH
    Exercise Regulation of Human Adipose Tissue
    Role: Principal Investigator
  3. R01DK099511 (GOODYEAR, LAURIE J) Apr 10, 2014 - Dec 31, 2023
    NIH
    Novel Mechanisms for Exercise Training Effects on Glucose Homeostasis
    Role: Principal Investigator
  4. R01DK101043 (GOODYEAR, LAURIE J) Sep 16, 2013 - Nov 30, 2022
    NIH
    Exercise regulation of glucose homeostasis
    Role: Principal Investigator
  5. R21DK091764 (GOODYEAR, LAURIE J) Apr 10, 2011 - Mar 31, 2013
    NIH
    Novel Mechanisms for Exercise Training Effects on Glucose Homeostasis
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kusuyama J, Makarewicz NS, Albertson BG, Alves-Wagner AB, Conlin RH, Prince NB, Alves CRR, Ramachandran K, Kozuka C, Xiudong Y, Xia Y, Hirshman MF, Hatta T, Nagatomi R, Nozik ES, Goodyear LJ. Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation. Diabetes. 2022 Mar 15. PMID: 35290440.
    Citations:    Fields:    
  2. Kozuka C, Efthymiou V, Sales VM, Zhou L, Osataphan S, Yuchi Y, Chimene-Weiss J, Mulla C, Isganaitis E, Desmond J, Sanechika S, Kusuyama J, Goodyear L, Shi X, Gerszten RE, Aguayo-Mazzucato C, Carapeto P, Teixeira SD, Sandoval D, Alonso-Curbelo D, Wu L, Qi J, Patti ME. Bromodomain Inhibition Reveals FGF15/19 as a Target of Epigenetic Regulation and Metabolic Control. Diabetes. 2022 Jan 31. PMID: 35100352.
    Citations:    Fields:    
  3. Queiroz AL, Lessard SJ, Ouchida AT, Araujo HN, Gonçalves DA, Simões Fróes Guimarães DSP, Teodoro BG, So K, Espreafico EM, Hirshman MF, Alberici LC, Kettelhut IDC, Goodyear LJ, Silveira LR. The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1a inhibition. Mol Metab. 2021 09; 51:101226. PMID: 33812060.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  4. Kusuyama J, Alves-Wagner AB, Conlin RH, Makarewicz NS, Albertson BG, Prince NB, Kobayashi S, Kozuka C, Møller M, Bjerre M, Fuglsang J, Miele E, Middelbeek RJW, Xiudong Y, Xia Y, Garneau L, Bhattacharjee J, Aguer C, Patti ME, Hirshman MF, Jessen N, Hatta T, Ovesen PG, Adamo KB, Nozik-Grayck E, Goodyear LJ. Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health. Cell Metab. 2021 05 04; 33(5):939-956.e8. PMID: 33770509.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  5. Nigro P, Middelbeek RJW, Alves CRR, Rovira-Llopis S, Ramachandran K, Rowland LA, Møller AB, Takahashi H, Alves-Wagner AB, Vamvini M, Makarewicz NS, Albertson BG, Hirshman MF, Goodyear LJ. Exercise Training Promotes Sex-Specific Adaptations in Mouse Inguinal White Adipose Tissue. Diabetes. 2021 06; 70(6):1250-1264. PMID: 33563587.
    Citations: 3     Fields:    Translation:AnimalsCells
  6. Middelbeek RJW, Motiani P, Brandt N, Nigro P, Zheng J, Virtanen KA, Kalliokoski KK, Hannukainen JC, Goodyear LJ. Exercise intensity regulates cytokine and klotho responses in men. Nutr Diabetes. 2021 01 07; 11(1):5. PMID: 33414377.
    Citations: 6     Fields:    Translation:Humans
  7. Kusuyama J, Alves-Wagner AB, Makarewicz NS, Goodyear LJ. Effects of maternal and paternal exercise on offspring metabolism. Nat Metab. 2020 09; 2(9):858-872. PMID: 32929233.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  8. Wang G, Yu Y, Cai W, Batista TM, Suk S, Noh HL, Hirshman M, Nigro P, Li ME, Softic S, Goodyear L, Kim JK, Kahn CR. Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance. Diabetes. 2020 11; 69(11):2294-2309. PMID: 32868340.
    Citations: 4     Fields:    Translation:Animals
  9. Yoon H, Spinelli JB, Zaganjor E, Wong SJ, German NJ, Randall EC, Dean A, Clermont A, Paulo JA, Garcia D, Li H, Rombold O, Agar NYR, Goodyear LJ, Shaw RJ, Gygi SP, Auwerx J, Haigis MC. PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle. Cell Metab. 2020 08 04; 32(2):215-228.e7. PMID: 32663458.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  10. Harris JE, Pinckard KM, Wright KR, Baer LA, Arts PJ, Abay E, Shettigar VK, Lehnig AC, Robertson B, Madaris K, Canova TJ, Sims C, Goodyear LJ, Andres A, Ziolo MT, Bode L, Stanford KI. Exercise-induced 3'-sialyllactose in breast milk is a critical mediator to improve metabolic health and cardiac function in mouse offspring. Nat Metab. 2020 08; 2(8):678-687. PMID: 32694823.
    Citations: 9     Fields:    Translation:HumansAnimals
  11. Alves CRR, Neves WD, de Almeida NR, Eichelberger EJ, Jannig PR, Voltarelli VA, Tobias GC, Bechara LRG, de Paula Faria D, Alves MJN, Hagen L, Sharma A, Slupphaug G, Moreira JBN, Wisloff U, Hirshman MF, Negrão CE, de Castro G, Chammas R, Swoboda KJ, Ruas JL, Goodyear LJ, Brum PC. Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN. Mol Metab. 2020 09; 39:101012. PMID: 32408015.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  12. Shamsi F, Xue R, Huang TL, Lundh M, Liu Y, Leiria LO, Lynes MD, Kempf E, Wang CH, Sugimoto S, Nigro P, Landgraf K, Schulz T, Li Y, Emanuelli B, Kothakota S, Williams LT, Jessen N, Pedersen SB, Böttcher Y, Blüher M, Körner A, Goodyear LJ, Mohammadi M, Kahn CR, Tseng YH. FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis. Nat Commun. 2020 03 17; 11(1):1421. PMID: 32184391.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  13. Zheng J, Alves-Wagner AB, Stanford KI, Prince NB, So K, Mul JD, Dirice E, Hirshman MF, Kulkarni RN, Goodyear LJ. Maternal and paternal exercise regulate offspring metabolic health and beta cell phenotype. BMJ Open Diabetes Res Care. 2020 02; 8(1). PMID: 32111717.
    Citations: 11     Translation:HumansAnimalsCells
  14. Penniman CM, Suarez Beltran PA, Bhardwaj G, Junck TL, Jena J, Poro K, Hirshman MF, Goodyear LJ, O'Neill BT. Loss of FoxOs in muscle reveals sex-based differences in insulin sensitivity but mitigates diet-induced obesity. Mol Metab. 2019 12; 30:203-220. PMID: 31767172.
    Citations: 7     Fields:    Translation:AnimalsCells
  15. Leiria LO, Wang CH, Lynes MD, Yang K, Shamsi F, Sato M, Sugimoto S, Chen EY, Bussberg V, Narain NR, Sansbury BE, Darcy J, Huang TL, Kodani SD, Sakaguchi M, Rocha AL, Schulz TJ, Bartelt A, Hotamisligil GS, Hirshman MF, van Leyen K, Goodyear LJ, Blüher M, Cypess AM, Kiebish MA, Spite M, Tseng YH. 12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat. Cell Metab. 2019 10 01; 30(4):768-783.e7. PMID: 31353262.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  16. Alves CRR, MacDonald TL, Nigro P, Pathak P, Hirshman MF, Goodyear LJ, Lessard SJ. Reduced sucrose nonfermenting AMPK-related kinase (SNARK) activity aggravates cancer-induced skeletal muscle wasting. Biomed Pharmacother. 2019 Sep; 117:109197. PMID: 31387190.
    Citations: 1     Fields:    Translation:Animals
  17. Motiani P, Teuho J, Saari T, Virtanen KA, Honkala SM, Middelbeek RJ, Goodyear LJ, Eskola O, Andersson J, Löyttyniemi E, Hannukainen JC, Nuutila P. Exercise training alters lipoprotein particles independent of brown adipose tissue metabolic activity. Obes Sci Pract. 2019 Jun; 5(3):258-272. PMID: 31275600.
    Citations: 3     
  18. Takahashi H, Alves CRR, Stanford KI, Middelbeek RJW, Ryan RE, Xue R, Sakaguchi M, Lynes MD, So K, Mul JD, Lee MY, Balan E, Pan H, Dreyfuss JM, Hirshman MF, Azhar M, Hannukainen JC, Nuutila P, Kalliokoski KK, Nielsen S, Pedersen BK, Kahn CR, Tseng YH, Goodyear LJ. TGF-ß2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism. Nat Metab. 2019 02; 1(2):291-303. PMID: 31032475.
    Citations: 44     Fields:    Translation:Animals
  19. Lehnig AC, Dewal RS, Baer LA, Kitching KM, Munoz VR, Arts PJ, Sindeldecker DA, May FJ, Lauritzen HPMM, Goodyear LJ, Stanford KI. Exercise Training Induces Depot-Specific Adaptations to White and Brown Adipose Tissue. iScience. 2019 Jan 25; 11:425-439. PMID: 30661000.
    Citations: 24     
  20. Stanford KI, Rasmussen M, Baer LA, Lehnig AC, Rowland LA, White JD, So K, De Sousa-Coelho AL, Hirshman MF, Patti ME, Rando OJ, Goodyear LJ. Paternal Exercise Improves Glucose Metabolism in Adult Offspring. Diabetes. 2018 12; 67(12):2530-2540. PMID: 30344184.
    Citations: 27     Fields:    Translation:AnimalsCells
  21. Sun XL, Lessard SJ, An D, Koh HJ, Esumi H, Hirshman MF, Goodyear LJ. Sucrose nonfermenting AMPK-related kinase (SNARK) regulates exercise-stimulated and ischemia-stimulated glucose transport in the heart. J Cell Biochem. 2019 01; 120(1):685-696. PMID: 30256437.
    Citations: 2     Fields:    Translation:AnimalsCells
  22. Wang H, Arias EB, Pataky MW, Goodyear LJ, Cartee GD. Postexercise improvement in glucose uptake occurs concomitant with greater ?3-AMPK activation and AS160 phosphorylation in rat skeletal muscle. Am J Physiol Endocrinol Metab. 2018 11 01; 315(5):E859-E871. PMID: 30130149.
    Citations: 8     Fields:    Translation:AnimalsCells
  23. Adachi Y, De Sousa-Coelho AL, Harata I, Aoun C, Weimer S, Shi X, Gonzalez Herrera KN, Takahashi H, Doherty C, Noguchi Y, Goodyear LJ, Haigis MC, Gerszten RE, Patti ME. l-Alanine activates hepatic AMP-activated protein kinase and modulates systemic glucose metabolism. Mol Metab. 2018 11; 17:61-70. PMID: 30190193.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  24. Lessard SJ, MacDonald TL, Pathak P, Han MS, Coffey VG, Edge J, Rivas DA, Hirshman MF, Davis RJ, Goodyear LJ. JNK regulates muscle remodeling via myostatin/SMAD inhibition. Nat Commun. 2018 08 02; 9(1):3030. PMID: 30072727.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  25. Stanford KI, Goodyear LJ. Muscle-Adipose Tissue Cross Talk. Cold Spring Harb Perspect Med. 2018 08 01; 8(8). PMID: 28507197.
    Citations: 33     Fields:    Translation:HumansAnimals
  26. Stanford KI, Lynes MD, Takahashi H, Baer LA, Arts PJ, May FJ, Lehnig AC, Middelbeek RJW, Richard JJ, So K, Chen EY, Gao F, Narain NR, Distefano G, Shettigar VK, Hirshman MF, Ziolo MT, Kiebish MA, Tseng YH, Coen PM, Goodyear LJ. 12,13-diHOME: An Exercise-Induced Lipokine that Increases Skeletal Muscle Fatty Acid Uptake. Cell Metab. 2018 Jun 05; 27(6):1357. PMID: 29874569.
    Citations: 10     Fields:    
  27. Mul JD, Soto M, Cahill ME, Ryan RE, Takahashi H, So K, Zheng J, Croote DE, Hirshman MF, la Fleur SE, Nestler EJ, Goodyear LJ. Voluntary wheel running promotes resilience to chronic social defeat stress in mice: a role for nucleus accumbens ?FosB. Neuropsychopharmacology. 2018 08; 43(9):1934-1942. PMID: 29875450.
    Citations: 15     Fields:    Translation:AnimalsCells
  28. Stanford KI, Lynes MD, Takahashi H, Baer LA, Arts PJ, May FJ, Lehnig AC, Middelbeek RJW, Richard JJ, So K, Chen EY, Gao F, Narain NR, Distefano G, Shettigar VK, Hirshman MF, Ziolo MT, Kiebish MA, Tseng YH, Coen PM, Goodyear LJ. 12,13-diHOME: An Exercise-Induced Lipokine that Increases Skeletal Muscle Fatty Acid Uptake. Cell Metab. 2018 May 01; 27(5):1111-1120.e3. PMID: 29719226.
    Citations: 70     Fields:    Translation:HumansAnimalsCells
  29. Arbiv OA, Cuvelier G, Klaassen RJ, Fernandez CV, Robitaille N, Steele M, Breakey V, Abish S, Wu J, Sinha R, Silva M, Goodyear L, Jardine L, Lipton JH, Corriveau-Bourque C, Brossard J, Michon B, Ghemlas I, Waespe N, Zlateska B, Sung L, Cada M, Dror Y. Molecular analysis and genotype-phenotype correlation of Diamond-Blackfan anemia. Clin Genet. 2018 02; 93(2):320-328. PMID: 29044489.
    Citations: 14     Fields:    Translation:Humans
  30. Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, Kiebish MA, Cypess AM, Blüher M, Goodyear LJ, Hotamisligil GS, Stanford KI, Tseng YH. Corrigendum: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue. Nat Med. 2017 Nov 07; 23(11):1384. PMID: 29117173.
    Citations: 5     Fields:    
  31. Choi RH, McConahay A, Jeong HW, McClellan JL, Hardee JP, Carson JA, Hirshman MF, Goodyear LJ, Koh HJ. Tribbles 3 regulates protein turnover in mouse skeletal muscle. Biochem Biophys Res Commun. 2017 11 25; 493(3):1236-1242. PMID: 28962861.
    Citations: 6     Fields:    Translation:AnimalsCells
  32. Laker RC, Drake JC, Wilson RJ, Lira VA, Lewellen BM, Ryall KA, Fisher CC, Zhang M, Saucerman JJ, Goodyear LJ, Kundu M, Yan Z. Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy. Nat Commun. 2017 09 15; 8(1):548. PMID: 28916822.
    Citations: 126     Fields:    Translation:HumansAnimalsCells
  33. Motiani P, Virtanen KA, Motiani KK, Eskelinen JJ, Middelbeek RJ, Goodyear LJ, Savolainen AM, Kemppainen J, Jensen J, Din MU, Saunavaara V, Parkkola R, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC. Decreased insulin-stimulated brown adipose tissue glucose uptake after short-term exercise training in healthy middle-aged men. Diabetes Obes Metab. 2017 10; 19(10):1379-1388. PMID: 28318098.
    Citations: 23     Fields:    Translation:Humans
  34. Stanford KI, Takahashi H, So K, Alves-Wagner AB, Prince NB, Lehnig AC, Getchell KM, Lee MY, Hirshman MF, Goodyear LJ. Maternal Exercise Improves Glucose Tolerance in Female Offspring. Diabetes. 2017 08; 66(8):2124-2136. PMID: 28572303.
    Citations: 33     Fields:    Translation:Animals
  35. Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, Kiebish MA, Cypess AM, Blüher M, Goodyear LJ, Hotamisligil GS, Stanford KI, Tseng YH. The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue. Nat Med. 2017 May; 23(5):631-637. PMID: 28346411.
    Citations: 122     Fields:    Translation:HumansAnimalsCells
  36. May FJ, Baer LA, Lehnig AC, So K, Chen EY, Gao F, Narain NR, Gushchina L, Rose A, Doseff AI, Kiebish MA, Goodyear LJ, Stanford KI. Lipidomic Adaptations in White and Brown Adipose Tissue in Response to Exercise Demonstrate Molecular Species-Specific Remodeling. Cell Rep. 2017 02 07; 18(6):1558-1572. PMID: 28178530.
    Citations: 33     Fields:    Translation:Animals
  37. Mul JD, Zheng J, Goodyear LJ. Validity Assessment of 5 Day Repeated Forced-Swim Stress to Model Human Depression in Young-Adult C57BL/6J and BALB/cJ Mice. eNeuro. 2016 Nov-Dec; 3(6). PMID: 28058270.
    Citations: 18     Fields:    Translation:Animals
  38. O'Neill BT, Lee KY, Klaus K, Softic S, Krumpoch MT, Fentz J, Stanford KI, Robinson MM, Cai W, Kleinridders A, Pereira RO, Hirshman MF, Abel ED, Accili D, Goodyear LJ, Nair KS, Kahn CR. Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis. J Clin Invest. 2016 09 01; 126(9):3433-46. PMID: 27525440.
    Citations: 60     Fields:    Translation:AnimalsCells
  39. Lerin C, Goldfine AB, Boes T, Liu M, Kasif S, Dreyfuss JM, De Sousa-Coelho AL, Daher G, Manoli I, Sysol JR, Isganaitis E, Jessen N, Goodyear LJ, Beebe K, Gall W, Venditti CP, Patti ME. Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism. Mol Metab. 2016 Oct; 5(10):926-936. PMID: 27689005.
    Citations: 49     Fields:    
  40. Schulz TJ, Graja A, Huang TL, Xue R, An D, Poehle-Kronawitter S, Lynes MD, Tolkachov A, O'Sullivan LE, Hirshman MF, Schupp M, Goodyear LJ, Mishina Y, Tseng YH. Loss of BMP receptor type 1A in murine adipose tissue attenuates age-related onset of insulin resistance. Diabetologia. 2016 08; 59(8):1769-77. PMID: 27209464.
    Citations: 5     Fields:    Translation:AnimalsCells
  41. Stanford KI, Goodyear LJ. Exercise regulation of adipose tissue. Adipocyte. 2016 Apr-Jun; 5(2):153-62. PMID: 27386159.
    Citations: 43     Fields:    
  42. Lessard SJ, Rivas DA, So K, Koh HJ, Queiroz AL, Hirshman MF, Fielding RA, Goodyear LJ. The AMPK-related kinase SNARK regulates muscle mass and myocyte survival. J Clin Invest. 2016 Feb; 126(2):560-70. PMID: 26690705.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  43. Ernande L, Stanford KI, Thoonen R, Zhang H, Clerte M, Hirshman MF, Goodyear LJ, Bloch KD, Buys ES, Scherrer-Crosbie M. Relationship of brown adipose tissue perfusion and function: a study through ß2-adrenoreceptor stimulation. J Appl Physiol (1985). 2016 Apr 15; 120(8):825-32. PMID: 26823340.
    Citations: 6     Fields:    Translation:Animals
  44. Jeong HW, Choi RH, McClellan JL, Piroli GG, Frizzell N, Tseng YH, Goodyear LJ, Koh HJ. Tribbles 3 inhibits brown adipocyte differentiation and function by suppressing insulin signaling. Biochem Biophys Res Commun. 2016 Feb 19; 470(4):783-91. PMID: 26801556.
    Citations: 3     Fields:    Translation:AnimalsCells
  45. Yu H, Fujii NL, Toyoda T, An D, Farese RV, Leitges M, Hirshman MF, Mul JD, Goodyear LJ. Contraction stimulates muscle glucose uptake independent of atypical PKC. Physiol Rep. 2015 Nov; 3(11). PMID: 26564060.
    Citations: 2     Fields:    
  46. Stanford KI, Middelbeek RJ, Goodyear LJ. Erratum. Exercise Effects on White Adipose Tissue: Beiging and Metabolic Adaptations. Diabetes 2015;64:2361-2368. Diabetes. 2015 Sep; 64(9):3334. PMID: 26294430.
    Citations: 2     Fields:    
  47. Lee KY, Singh MK, Ussar S, Wetzel P, Hirshman MF, Goodyear LJ, Kispert A, Kahn CR. Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism. Nat Commun. 2015 Aug 24; 6:8054. PMID: 26299309.
    Citations: 32     Fields:    Translation:AnimalsCells
  48. Zhang H, Guan M, Townsend KL, Huang TL, An D, Yan X, Xue R, Schulz TJ, Winnay J, Mori M, Hirshman MF, Kristiansen K, Tsang JS, White AP, Cypess AM, Goodyear LJ, Tseng YH. MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1a signaling network. EMBO Rep. 2015 Oct; 16(10):1378-93. PMID: 26303948.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  49. Mul JD, Stanford KI, Hirshman MF, Goodyear LJ. Exercise and Regulation of Carbohydrate Metabolism. Prog Mol Biol Transl Sci. 2015; 135:17-37. PMID: 26477909.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  50. Obici S, Magrisso IJ, Ghazarian AS, Shirazian A, Miller JR, Loyd CM, Begg DP, Krawczewski Carhuatanta KA, Haas MK, Davis JF, Woods SC, Sandoval DA, Seeley RJ, Goodyear LJ, Pothos EN, Mul JD. Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation. Mol Metab. 2015 Oct; 4(10):692-705. PMID: 26500841.
    Citations: 11     Fields:    
  51. Xue R, Lynes MD, Dreyfuss JM, Shamsi F, Schulz TJ, Zhang H, Huang TL, Townsend KL, Li Y, Takahashi H, Weiner LS, White AP, Lynes MS, Rubin LL, Goodyear LJ, Cypess AM, Tseng YH. Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes. Nat Med. 2015 Jul; 21(7):760-8. PMID: 26076036.
    Citations: 117     Fields:    Translation:HumansCells
  52. Stanford KI, Middelbeek RJ, Goodyear LJ. Exercise Effects on White Adipose Tissue: Beiging and Metabolic Adaptations. Diabetes. 2015 Jul; 64(7):2361-8. PMID: 26050668.
    Citations: 117     Fields:    Translation:HumansAnimalsCells
  53. O'Neill BT, Lauritzen HP, Hirshman MF, Smyth G, Goodyear LJ, Kahn CR. Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis. Cell Rep. 2015 May 26; 11(8):1220-35. PMID: 25981038.
    Citations: 60     Fields:    Translation:AnimalsCells
  54. Stanford KI, Middelbeek RJ, Townsend KL, Lee MY, Takahashi H, So K, Hitchcox KM, Markan KR, Hellbach K, Hirshman MF, Tseng YH, Goodyear LJ. A novel role for subcutaneous adipose tissue in exercise-induced improvements in glucose homeostasis. Diabetes. 2015 Jun; 64(6):2002-14. PMID: 25605808.
    Citations: 133     Fields:    Translation:Animals
  55. Stanford KI, Goodyear LJ. Exercise and type 2 diabetes: molecular mechanisms regulating glucose uptake in skeletal muscle. Adv Physiol Educ. 2014 Dec; 38(4):308-14. PMID: 25434013.
    Citations: 71     Fields:    Translation:Humans
  56. Stanford KI, Lee MY, Getchell KM, So K, Hirshman MF, Goodyear LJ. Exercise before and during pregnancy prevents the deleterious effects of maternal high-fat feeding on metabolic health of male offspring. Diabetes. 2015 Feb; 64(2):427-33. PMID: 25204976.
    Citations: 50     Fields:    Translation:Animals
  57. Rivas DA, Lessard SJ, Rice NP, Lustgarten MS, So K, Goodyear LJ, Parnell LD, Fielding RA. Diminished skeletal muscle microRNA expression with aging is associated with attenuated muscle plasticity and inhibition of IGF-1 signaling. FASEB J. 2014 Sep; 28(9):4133-47. PMID: 24928197.
    Citations: 59     Fields:    Translation:HumansCells
  58. Vendelbo MH, Møller AB, Treebak JT, Gormsen LC, Goodyear LJ, Wojtaszewski JF, Jørgensen JO, Møller N, Jessen N. Sustained AS160 and TBC1D1 phosphorylations in human skeletal muscle 30 min after a single bout of exercise. J Appl Physiol (1985). 2014 Aug 01; 117(3):289-96. PMID: 24876356.
    Citations: 16     Fields:    Translation:HumansCells
  59. Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, Miller C, Regalado SG, Loffredo FS, Pancoast JR, Hirshman MF, Lebowitz J, Shadrach JL, Cerletti M, Kim MJ, Serwold T, Goodyear LJ, Rosner B, Lee RT, Wagers AJ. Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle. Science. 2014 May 09; 344(6184):649-52. PMID: 24797481.
    Citations: 336     Fields:    Translation:AnimalsCells
  60. An D, Lessard SJ, Toyoda T, Lee MY, Koh HJ, Qi L, Hirshman MF, Goodyear LJ. Overexpression of TRB3 in muscle alters muscle fiber type and improves exercise capacity in mice. Am J Physiol Regul Integr Comp Physiol. 2014 Jun 15; 306(12):R925-33. PMID: 24740654.
    Citations: 10     Fields:    Translation:AnimalsCells
  61. Kristensen JM, Treebak JT, Schjerling P, Goodyear L, Wojtaszewski JF. Two weeks of metformin treatment induces AMPK-dependent enhancement of insulin-stimulated glucose uptake in mouse soleus muscle. Am J Physiol Endocrinol Metab. 2014 May 15; 306(10):E1099-109. PMID: 24644243.
    Citations: 23     Fields:    Translation:Animals
  62. Treebak JT, Pehmøller C, Kristensen JM, Kjøbsted R, Birk JB, Schjerling P, Richter EA, Goodyear LJ, Wojtaszewski JF. Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 proteins in human skeletal muscle. J Physiol. 2014 Jan 15; 592(2):351-75. PMID: 24247980.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  63. Stanford KI, Goodyear LJ. The therapeutic potential of brown adipose tissue. Hepatobiliary Surg Nutr. 2013 Oct; 2(5):286-7. PMID: 24570961.
    Citations: 5     
  64. Brandauer J, Vienberg SG, Andersen MA, Ringholm S, Risis S, Larsen PS, Kristensen JM, Frøsig C, Leick L, Fentz J, Jørgensen S, Kiens B, Wojtaszewski JF, Richter EA, Zierath JR, Goodyear LJ, Pilegaard H, Treebak JT. AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle. J Physiol. 2013 Oct 15; 591(20):5207-20. PMID: 23918774.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  65. Olesen J, Ringholm S, Nielsen MM, Brandt CT, Pedersen JT, Halling JF, Goodyear LJ, Pilegaard H. Role of PGC-1a in exercise training- and resveratrol-induced prevention of age-associated inflammation. Exp Gerontol. 2013 Nov; 48(11):1274-84. PMID: 23916840.
    Citations: 16     Fields:    Translation:AnimalsCells
  66. Lauritzen HP, Brandauer J, Schjerling P, Koh HJ, Treebak JT, Hirshman MF, Galbo H, Goodyear LJ. Contraction and AICAR stimulate IL-6 vesicle depletion from skeletal muscle fibers in vivo. Diabetes. 2013 Sep; 62(9):3081-92. PMID: 23761105.
    Citations: 17     Fields:    Translation:AnimalsCells
  67. Middelbeek RJ, Chambers MA, Tantiwong P, Treebak JT, An D, Hirshman MF, Musi N, Goodyear LJ. Insulin stimulation regulates AS160 and TBC1D1 phosphorylation sites in human skeletal muscle. Nutr Diabetes. 2013 Jun 10; 3:e74. PMID: 23752133.
    Citations: 16     Fields:    
  68. Rowe GC, Patten IS, Zsengeller ZK, El-Khoury R, Okutsu M, Bampoh S, Koulisis N, Farrell C, Hirshman MF, Yan Z, Goodyear LJ, Rustin P, Arany Z. Disconnecting mitochondrial content from respiratory chain capacity in PGC-1-deficient skeletal muscle. Cell Rep. 2013 May 30; 3(5):1449-56. PMID: 23707060.
    Citations: 49     Fields:    Translation:AnimalsCells
  69. Lessard SJ, Rivas DA, Alves-Wagner AB, Hirshman MF, Gallagher IJ, Constantin-Teodosiu D, Atkins R, Greenhaff PL, Qi NR, Gustafsson T, Fielding RA, Timmons JA, Britton SL, Koch LG, Goodyear LJ. Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks. Diabetes. 2013 Aug; 62(8):2717-27. PMID: 23610057.
    Citations: 42     Fields:    Translation:AnimalsCells
  70. Friedrichsen M, Birk JB, Richter EA, Ribel-Madsen R, Pehmøller C, Hansen BF, Beck-Nielsen H, Hirshman MF, Goodyear LJ, Vaag A, Poulsen P, Wojtaszewski JF. Akt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH2-terminal (sites 2 + 2a) phosphorylation. Am J Physiol Endocrinol Metab. 2013 Mar 15; 304(6):E631-9. PMID: 23321478.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  71. Manabe Y, Gollisch KS, Holton L, Kim YB, Brandauer J, Fujii NL, Hirshman MF, Goodyear LJ. Exercise training-induced adaptations associated with increases in skeletal muscle glycogen content. FEBS J. 2013 Feb; 280(3):916-26. PMID: 23206309.
    Citations: 15     Fields:    Translation:Animals
  72. Liew CW, Boucher J, Cheong JK, Vernochet C, Koh HJ, Mallol C, Townsend K, Langin D, Kawamori D, Hu J, Tseng YH, Hellerstein MK, Farmer SR, Goodyear L, Doria A, Blüher M, Hsu SI, Kulkarni RN. Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. Nat Med. 2013 Feb; 19(2):217-26. PMID: 23291629.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  73. Koh HJ, Toyoda T, Didesch MM, Lee MY, Sleeman MW, Kulkarni RN, Musi N, Hirshman MF, Goodyear LJ. Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle. Nat Commun. 2013; 4:1871. PMID: 23695665.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  74. Manabe Y, Miyatake S, Takagi M, Nakamura M, Okeda A, Nakano T, Hirshman MF, Goodyear LJ, Fujii NL. Characterization of an acute muscle contraction model using cultured C2C12 myotubes. PLoS One. 2012; 7(12):e52592. PMID: 23300713.
    Citations: 44     Fields:    Translation:AnimalsCells
  75. Stanford KI, Middelbeek RJ, Townsend KL, An D, Nygaard EB, Hitchcox KM, Markan KR, Nakano K, Hirshman MF, Tseng YH, Goodyear LJ. Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. J Clin Invest. 2013 Jan; 123(1):215-23. PMID: 23221344.
    Citations: 430     Fields:    Translation:Animals
  76. Townsend KL, An D, Lynes MD, Huang TL, Zhang H, Goodyear LJ, Tseng YH. Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake. Antioxid Redox Signal. 2013 Jul 20; 19(3):243-57. PMID: 22938691.
    Citations: 37     Fields:    Translation:AnimalsCells
  77. Pehmøller C, Brandt N, Birk JB, Høeg LD, Sjøberg KA, Goodyear LJ, Kiens B, Richter EA, Wojtaszewski JF. Exercise alleviates lipid-induced insulin resistance in human skeletal muscle-signaling interaction at the level of TBC1 domain family member 4. Diabetes. 2012 Nov; 61(11):2743-52. PMID: 22851577.
    Citations: 44     Fields:    Translation:HumansCells
  78. Henstridge DC, Bruce CR, Pang CP, Lancaster GI, Allen TL, Estevez E, Gardner T, Weir JM, Meikle PJ, Lam KSL, Xu A, Fujii N, Goodyear LJ, Febbraio MA. Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice. Diabetologia. 2012 Oct; 55(10):2769-2778. PMID: 22832498.
    Citations: 23     Fields:    Translation:AnimalsCells
  79. Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL. AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation. Nat Med. 2012 Jan 08; 18(2):244-51. PMID: 22231556.
    Citations: 54     Fields:    Translation:AnimalsCells
  80. Vendelbo MH, Clasen BF, Treebak JT, Møller L, Krusenstjerna-Hafstrøm T, Madsen M, Nielsen TS, Stødkilde-Jørgensen H, Pedersen SB, Jørgensen JO, Goodyear LJ, Wojtaszewski JF, Møller N, Jessen N. Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle. Am J Physiol Endocrinol Metab. 2012 Jan 15; 302(2):E190-200. PMID: 22028408.
    Citations: 21     Fields:    Translation:HumansCells
  81. Jessen N, An D, Lihn AS, Nygren J, Hirshman MF, Thorell A, Goodyear LJ. Exercise increases TBC1D1 phosphorylation in human skeletal muscle. Am J Physiol Endocrinol Metab. 2011 Jul; 301(1):E164-71. PMID: 21505148.
    Citations: 29     Fields:    Translation:HumansCellsCTClinical Trials
  82. Toyoda T, An D, Witczak CA, Koh HJ, Hirshman MF, Fujii N, Goodyear LJ. Myo1c regulates glucose uptake in mouse skeletal muscle. J Biol Chem. 2011 Feb 11; 286(6):4133-40. PMID: 21127070.
    Citations: 21     Fields:    Translation:AnimalsCells
  83. Vichaiwong K, Purohit S, An D, Toyoda T, Jessen N, Hirshman MF, Goodyear LJ. Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle. Biochem J. 2010 Oct 15; 431(2):311-20. PMID: 20701589.
    Citations: 41     Fields:    Translation:AnimalsCells
  84. Koh HJ, Toyoda T, Fujii N, Jung MM, Rathod A, Middelbeek RJ, Lessard SJ, Treebak JT, Tsuchihara K, Esumi H, Richter EA, Wojtaszewski JF, Hirshman MF, Goodyear LJ. Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle. Proc Natl Acad Sci U S A. 2010 Aug 31; 107(35):15541-6. PMID: 20713714.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  85. Lauritzen HP, Galbo H, Toyoda T, Goodyear LJ. Kinetics of contraction-induced GLUT4 translocation in skeletal muscle fibers from living mice. Diabetes. 2010 Sep; 59(9):2134-44. PMID: 20622170.
    Citations: 39     Fields:    Translation:AnimalsCells
  86. Jessen N, Goodyear LJ. Diabetes: Exercise and type 2 diabetes mellitus--good for body and mind? Nat Rev Endocrinol. 2010 Jun; 6(6):303-4. PMID: 20502463.
    Citations: 1     Fields:    Translation:Humans
  87. Jessen N, Koh HJ, Folmes CD, Wagg C, Fujii N, Løfgren B, Wolf CM, Berul CI, Hirshman MF, Lopaschuk GD, Goodyear LJ. Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function. Biochim Biophys Acta. 2010 Jul-Aug; 1802(7-8):593-600. PMID: 20441792.
    Citations: 26     Fields:    Translation:AnimalsCells
  88. An D, Toyoda T, Taylor EB, Yu H, Fujii N, Hirshman MF, Goodyear LJ. TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle. Diabetes. 2010 Jun; 59(6):1358-65. PMID: 20299473.
    Citations: 65     Fields:    Translation:AnimalsCells
  89. Witczak CA, Jessen N, Warro DM, Toyoda T, Fujii N, Anderson ME, Hirshman MF, Goodyear LJ. CaMKII regulates contraction- but not insulin-induced glucose uptake in mouse skeletal muscle. Am J Physiol Endocrinol Metab. 2010 Jun; 298(6):E1150-60. PMID: 20215576.
    Citations: 30     Fields:    Translation:Animals
  90. Sharoff CG, Hagobian TA, Malin SK, Chipkin SR, Yu H, Hirshman MF, Goodyear LJ, Braun B. Combining short-term metformin treatment and one bout of exercise does not increase insulin action in insulin-resistant individuals. Am J Physiol Endocrinol Metab. 2010 Apr; 298(4):E815-23. PMID: 20071560.
    Citations: 43     Fields:    Translation:HumansCells
  91. Treebak JT, Taylor EB, Witczak CA, An D, Toyoda T, Koh HJ, Xie J, Feener EP, Wojtaszewski JF, Hirshman MF, Goodyear LJ. Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle. Am J Physiol Cell Physiol. 2010 Feb; 298(2):C377-85. PMID: 19923418.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  92. Palacios OM, Carmona JJ, Michan S, Chen KY, Manabe Y, Ward JL, Goodyear LJ, Tong Q. Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle. Aging (Albany NY). 2009 Aug 15; 1(9):771-83. PMID: 20157566.
    Citations: 203     Fields:    Translation:AnimalsCells
  93. Gollisch KS, Brandauer J, Jessen N, Toyoda T, Nayer A, Hirshman MF, Goodyear LJ. Effects of exercise training on subcutaneous and visceral adipose tissue in normal- and high-fat diet-fed rats. Am J Physiol Endocrinol Metab. 2009 Aug; 297(2):E495-504. PMID: 19491293.
    Citations: 95     Fields:    Translation:Animals
  94. Chambers MA, Moylan JS, Smith JD, Goodyear LJ, Reid MB. Stretch-stimulated glucose uptake in skeletal muscle is mediated by reactive oxygen species and p38 MAP-kinase. J Physiol. 2009 Jul 01; 587(Pt 13):3363-73. PMID: 19403598.
    Citations: 54     Fields:    Translation:AnimalsCells
  95. Rogers NH, Witczak CA, Hirshman MF, Goodyear LJ, Greenberg AS. Estradiol stimulates Akt, AMP-activated protein kinase (AMPK) and TBC1D1/4, but not glucose uptake in rat soleus. Biochem Biophys Res Commun. 2009 May 15; 382(4):646-50. PMID: 19265681.
    Citations: 46     Fields:    Translation:Animals
  96. Witczak CA, Sharoff CG, Goodyear LJ. AMP-activated protein kinase in skeletal muscle: from structure and localization to its role as a master regulator of cellular metabolism. Cell Mol Life Sci. 2008 Nov; 65(23):3737-55. PMID: 18810325.
    Citations: 94     Fields:    
  97. Goodyear LJ. The exercise pill--too good to be true? N Engl J Med. 2008 Oct 23; 359(17):1842-4. PMID: 18946072.
    Citations: 41     Fields:    Translation:HumansAnimals
  98. Fujii N, Ho RC, Manabe Y, Jessen N, Toyoda T, Holland WL, Summers SA, Hirshman MF, Goodyear LJ. Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice. Diabetes. 2008 Nov; 57(11):2958-66. PMID: 18728234.
    Citations: 53     Fields:    Translation:Animals
  99. Norris AW, Hirshman MF, Yao J, Jessen N, Musi N, Chen L, Sivitz WI, Goodyear LJ, Kahn CR. Endogenous peroxisome proliferator-activated receptor-gamma augments fatty acid uptake in oxidative muscle. Endocrinology. 2008 Nov; 149(11):5374-83. PMID: 18653710.
    Citations: 6     Fields:    Translation:AnimalsCells
  100. Cerletti M, Jurga S, Witczak CA, Hirshman MF, Shadrach JL, Goodyear LJ, Wagers AJ. Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles. Cell. 2008 Jul 11; 134(1):37-47. PMID: 18614009.
    Citations: 216     Fields:    Translation:HumansAnimalsCells
  101. Koh HJ, Brandauer J, Goodyear LJ. LKB1 and AMPK and the regulation of skeletal muscle metabolism. Curr Opin Clin Nutr Metab Care. 2008 May; 11(3):227-32. PMID: 18403917.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  102. Röckl KS, Witczak CA, Goodyear LJ. Signaling mechanisms in skeletal muscle: acute responses and chronic adaptations to exercise. IUBMB Life. 2008 Mar; 60(3):145-53. PMID: 18380005.
    Citations: 80     Fields:    Translation:HumansCells
  103. Higaki Y, Mikami T, Fujii N, Hirshman MF, Koyama K, Seino T, Tanaka K, Goodyear LJ. Oxidative stress stimulates skeletal muscle glucose uptake through a phosphatidylinositol 3-kinase-dependent pathway. Am J Physiol Endocrinol Metab. 2008 May; 294(5):E889-97. PMID: 18303121.
    Citations: 45     Fields:    Translation:AnimalsCells
  104. Taylor EB, An D, Kramer HF, Yu H, Fujii NL, Roeckl KS, Bowles N, Hirshman MF, Xie J, Feener EP, Goodyear LJ. Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle. J Biol Chem. 2008 Apr 11; 283(15):9787-96. PMID: 18276596.
    Citations: 110     Fields:    Translation:AnimalsCells
  105. Taylor EB, Goodyear LJ. Targeting skeletal muscle AMP-activated protein kinase to treat type 2 diabetes. Curr Diab Rep. 2007 Dec; 7(6):399-401. PMID: 18254999.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  106. Bouskila M, Hirshman MF, Jensen J, Goodyear LJ, Sakamoto K. Insulin promotes glycogen synthesis in the absence of GSK3 phosphorylation in skeletal muscle. Am J Physiol Endocrinol Metab. 2008 Jan; 294(1):E28-35. PMID: 18003720.
    Citations: 35     Fields:    Translation:AnimalsCells
  107. Lauritzen HP, Galbo H, Brandauer J, Goodyear LJ, Ploug T. Large GLUT4 vesicles are stationary while locally and reversibly depleted during transient insulin stimulation of skeletal muscle of living mice: imaging analysis of GLUT4-enhanced green fluorescent protein vesicle dynamics. Diabetes. 2008 Feb; 57(2):315-24. PMID: 17977960.
    Citations: 31     Fields:    Translation:AnimalsCells
  108. Kramer HF, Taylor EB, Witczak CA, Fujii N, Hirshman MF, Goodyear LJ. Calmodulin-binding domain of AS160 regulates contraction- but not insulin-stimulated glucose uptake in skeletal muscle. Diabetes. 2007 Dec; 56(12):2854-62. PMID: 17717281.
    Citations: 29     Fields:    Translation:AnimalsCells
  109. Ho RC, Fujii N, Witters LA, Hirshman MF, Goodyear LJ. Dissociation of AMP-activated protein kinase and p38 mitogen-activated protein kinase signaling in skeletal muscle. Biochem Biophys Res Commun. 2007 Oct 19; 362(2):354-9. PMID: 17709097.
    Citations: 7     Fields:    Translation:AnimalsCells
  110. Röckl KS, Hirshman MF, Brandauer J, Fujii N, Witters LA, Goodyear LJ. Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift. Diabetes. 2007 Aug; 56(8):2062-9. PMID: 17513699.
    Citations: 115     Fields:    Translation:Animals
  111. Koh HJ, Hirshman MF, He H, Li Y, Manabe Y, Balschi JA, Goodyear LJ. Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes. Biochem J. 2007 May 01; 403(3):473-81. PMID: 17253964.
    Citations: 54     Fields:    Translation:AnimalsCells
  112. Fujii N, Seifert MM, Kane EM, Peter LE, Ho RC, Winstead S, Hirshman MF, Goodyear LJ. Role of AMP-activated protein kinase in exercise capacity, whole body glucose homeostasis, and glucose transport in skeletal muscle -insight from analysis of a transgenic mouse model-. Diabetes Res Clin Pract. 2007 Sep; 77 Suppl 1:S92-8. PMID: 17452058.
    Citations: 22     Fields:    Translation:Animals
  113. Luptak I, Shen M, He H, Hirshman MF, Musi N, Goodyear LJ, Yan J, Wakimoto H, Morita H, Arad M, Seidman CE, Seidman JG, Ingwall JS, Balschi JA, Tian R. Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage. J Clin Invest. 2007 May; 117(5):1432-9. PMID: 17431505.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  114. Kramer HF, Goodyear LJ. Exercise, MAPK, and NF-kappaB signaling in skeletal muscle. J Appl Physiol (1985). 2007 Jul; 103(1):388-95. PMID: 17303713.
    Citations: 126     Fields:    Translation:HumansAnimalsCells
  115. Witczak CA, Fujii N, Hirshman MF, Goodyear LJ. Ca2+/calmodulin-dependent protein kinase kinase-alpha regulates skeletal muscle glucose uptake independent of AMP-activated protein kinase and Akt activation. Diabetes. 2007 May; 56(5):1403-9. PMID: 17287469.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  116. Barré L, Richardson C, Hirshman MF, Brozinick J, Fiering S, Kemp BE, Goodyear LJ, Witters LA. Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation. Am J Physiol Endocrinol Metab. 2007 Mar; 292(3):E802-11. PMID: 17106064.
    Citations: 23     Fields:    Translation:Animals
  117. Witczak CA, Hirshman MF, Jessen N, Fujii N, Seifert MM, Brandauer J, Hotamisligil GS, Goodyear LJ. JNK1 deficiency does not enhance muscle glucose metabolism in lean mice. Biochem Biophys Res Commun. 2006 Dec 01; 350(4):1063-8. PMID: 17045576.
    Citations: 8     Fields:    Translation:Animals
  118. Koh HJ, Arnolds DE, Fujii N, Tran TT, Rogers MJ, Jessen N, Li Y, Liew CW, Ho RC, Hirshman MF, Kulkarni RN, Kahn CR, Goodyear LJ. Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3. Mol Cell Biol. 2006 Nov; 26(22):8217-27. PMID: 16966378.
    Citations: 98     Fields:    Translation:AnimalsCells
  119. Kramer HF, Witczak CA, Taylor EB, Fujii N, Hirshman MF, Goodyear LJ. AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle. J Biol Chem. 2006 Oct 20; 281(42):31478-85. PMID: 16935857.
    Citations: 112     Fields:    Translation:AnimalsCells
  120. Howlett KF, Sakamoto K, Yu H, Goodyear LJ, Hargreaves M. Insulin-stimulated insulin receptor substrate-2-associated phosphatidylinositol 3-kinase activity is enhanced in human skeletal muscle after exercise. Metabolism. 2006 Aug; 55(8):1046-52. PMID: 16839840.
    Citations: 16