Harvard Catalyst Profiles

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Georg Lauer, Ph.D., M.D.

Co-Author

This page shows the publications co-authored by Georg Lauer and Todd Allen.
Connection Strength

2.054
  1. Differentiation of exhausted CD8+ T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory. Nat Immunol. 2021 08; 22(8):1030-1041.
    View in: PubMed
    Score: 0.237
  2. Early Transcriptional Divergence Marks Virus-Specific Primary Human CD8+ T Cells in Chronic versus Acute Infection. Immunity. 2017 10 17; 47(4):648-663.e8.
    View in: PubMed
    Score: 0.183
  3. Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence. J Exp Med. 2012 Jan 16; 209(1):61-75.
    View in: PubMed
    Score: 0.122
  4. Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations. Hepatology. 2011 Oct; 54(4):1157-66.
    View in: PubMed
    Score: 0.120
  5. Compensatory mutations restore the replication defects caused by cytotoxic T lymphocyte escape mutations in hepatitis C virus polymerase. J Virol. 2011 Nov; 85(22):11883-90.
    View in: PubMed
    Score: 0.119
  6. Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes. Gastroenterology. 2011 Feb; 140(2):686-696.e1.
    View in: PubMed
    Score: 0.112
  7. Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution. J Virol. 2010 Feb; 84(3):1656-63.
    View in: PubMed
    Score: 0.105
  8. Temporal dynamics of a predominant protease inhibitor-resistance mutation in a treatment-naive, hepatitis C virus-infected individual. J Infect Dis. 2009 Mar 01; 199(5):737-41.
    View in: PubMed
    Score: 0.100
  9. Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients. Hepatology. 2008 Dec; 48(6):1769-78.
    View in: PubMed
    Score: 0.099
  10. High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome. J Virol. 2008 Mar; 82(6):3154-60.
    View in: PubMed
    Score: 0.093
  11. Viral sequence evolution in acute hepatitis C virus infection. J Virol. 2007 Nov; 81(21):11658-68.
    View in: PubMed
    Score: 0.090
  12. Human leukocyte antigen-associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution. Hepatology. 2007 Aug; 46(2):339-49.
    View in: PubMed
    Score: 0.090
  13. Characterization of full-length hepatitis C virus genotype 4 sequences. J Viral Hepat. 2007 May; 14(5):330-7.
    View in: PubMed
    Score: 0.088
  14. Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy. J Virol. 2005 Oct; 79(20):12979-88.
    View in: PubMed
    Score: 0.079
  15. CD8 epitope escape and reversion in acute HCV infection. J Exp Med. 2004 Dec 20; 200(12):1593-604.
    View in: PubMed
    Score: 0.075
  16. High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection. Gastroenterology. 2004 Sep; 127(3):924-36.
    View in: PubMed
    Score: 0.074
  17. Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans. Nat Immunol. 2021 08; 22(8):1020-1029.
    View in: PubMed
    Score: 0.059
  18. The epigenetic landscape of T cell exhaustion. Science. 2016 12 02; 354(6316):1165-1169.
    View in: PubMed
    Score: 0.043
  19. Distinct Escape Pathway by Hepatitis C Virus Genotype 1a from a Dominant CD8+ T Cell Response by Selection of Altered Epitope Processing. J Virol. 2016 01 01; 90(1):33-42.
    View in: PubMed
    Score: 0.040
  20. HLA-B*27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope. J Hepatol. 2014 Jan; 60(1):22-9.
    View in: PubMed
    Score: 0.034
  21. Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope. Hepatology. 2010 Jan; 51(1):54-62.
    View in: PubMed
    Score: 0.027
  22. Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non-genotype 1 infection. Blood. 2007 Sep 01; 110(5):1559-69.
    View in: PubMed
    Score: 0.022
  23. Impaired hepatitis C virus-specific T cell responses and recurrent hepatitis C virus in HIV coinfection. PLoS Med. 2006 Dec; 3(12):e492.
    View in: PubMed
    Score: 0.021
  24. Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes. J Immunol. 2005 Sep 15; 175(6):3603-13.
    View in: PubMed
    Score: 0.020
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.