Harvard Catalyst Profiles

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Walter Fleming Stafford III, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lee E, Salamat-Miller N, Stafford WF, Taylor K. Self-association of human beta-galactocerebrosidase: Dependence on pH, salt, and surfactant. PLoS One. 2019; 14(12):e0226618. PMID: 31869371; PMCID: PMC6927645.
    Citations:    Fields:    Translation:HumansCells
  2. Uttinger MJ, Wawra SE, Guckeisen T, Walter J, Bear A, Thajudeen T, Sherwood PJ, Smith A, Wagemans AM, Stafford WF, Peukert W. A Comprehensive Brownian Dynamics Approach for the Determination of Non-ideality Parameters from Analytical Ultracentrifugation. Langmuir. 2019 09 03; 35(35):11491-11502. PMID: 31385708.
    Citations: 1     Fields:    
  3. Wright RT, Hayes D, Sherwood PJ, Stafford WF, Correia JJ. AUC measurements of diffusion coefficients of monoclonal antibodies in the presence of human serum proteins. Eur Biophys J. 2018 Oct; 47(7):709-722. PMID: 30003300.
    Citations: 7     Fields:    Translation:HumansCells
  4. Yang D, Correia JJ, Stafford Iii WF, Roberts CJ, Singh S, Hayes D, Kroe-Barrett R, Nixon A, Laue TM. Weak IgG self- and hetero-association characterized by fluorescence analytical ultracentrifugation. Protein Sci. 2018 07; 27(7):1334-1348. PMID: 29637644; PMCID: PMC6032368.
    Citations: 9     Fields:    Translation:HumansCells
  5. Wright RT, Hayes DB, Stafford WF, Sherwood PJ, Correia JJ. Characterization of therapeutic antibodies in the presence of human serum proteins by AU-FDS analytical ultracentrifugation. Anal Biochem. 2018 06 01; 550:72-83. PMID: 29654743.
    Citations: 13     Fields:    Translation:Humans
  6. Kokona B, May CA, Cunningham NR, Richmond L, Jay Garcia F, Durante JC, Ulrich KM, Roberts CM, Link CD, Stafford WF, Laue TM, Fairman R. Studying polyglutamine aggregation in Caenorhabditis elegans using an analytical ultracentrifuge equipped with fluorescence detection. Protein Sci. 2016 Mar; 25(3):605-17. PMID: 26647351; PMCID: PMC4815402.
    Citations: 5     Fields:    Translation:AnimalsCells
  7. Lee E, Stafford WF. Interaction of Myosin Phosphatase Target Subunit (MYPT1) with Myosin Phosphatase-RhoA Interacting Protein (MRIP): A Role of Glutamic Acids in the Interaction. PLoS One. 2015; 10(10):e0139875. PMID: 26445108.
    Citations:    Fields:    Translation:HumansCells
  8. Correia JJ, Stafford WF. Sedimentation Velocity: A Classical Perspective. Methods Enzymol. 2015; 562:49-80. PMID: 26412647.
    Citations: 8     Fields:    
  9. Walter J, Sherwood PJ, Lin W, Segets D, Stafford WF, Peukert W. Simultaneous analysis of hydrodynamic and optical properties using analytical ultracentrifugation equipped with multiwavelength detection. Anal Chem. 2015 Mar 17; 87(6):3396-403. PMID: 25679871.
    Citations: 14     Fields:    
  10. Graceffa P, Lee E, Stafford WF. Disulfide cross-linked antiparallel actin dimer. Biochemistry. 2013 Feb 12; 52(6):1082-8. PMID: 23293916.
    Citations:    Fields:    Translation:AnimalsCells
  11. Bansal N, Zhang M, Bhaskar A, Itotia P, Lee E, Shlyakhtenko LS, Lam TT, Fritz A, Berezney R, Lyubchenko YL, Stafford WF, Thapar R. Assembly of the SLIP1-SLBP complex on histone mRNA requires heterodimerization and sequential binding of SLBP followed by SLIP1. Biochemistry. 2013 Jan 22; 52(3):520-36. PMID: 23286197.
    Citations: 11     Fields:    Translation:HumansCells
  12. Stafford WF, Lee E, Graceffa P. Equilibrium self-association of tropomyosin. FEBS Lett. 2012 Nov 02; 586(21):3840-2. PMID: 23022558.
    Citations:    Fields:    Translation:AnimalsCells
  13. Gordon JM, Shikov S, Kuehner JN, Liriano M, Lee E, Stafford W, Poulsen MB, Harrison C, Moore C, Bohm A. Reconstitution of CF IA from overexpressed subunits reveals stoichiometry and provides insights into molecular topology. Biochemistry. 2011 Nov 29; 50(47):10203-14. PMID: 22026644.
    Citations: 16     Fields:    Translation:AnimalsCells
  14. Li Y, Stafford WF, Hesselberg M, Hayes D, Wu Z, Byrne M. Characterization of the self-association of human interferon-a2b, albinterferon-a2b, and pegasys. J Pharm Sci. 2012 Jan; 101(1):68-80. PMID: 21975852.
    Citations: 4     Fields:    Translation:HumansCells
  15. Cole JL, Correia JJ, Stafford WF. The use of analytical sedimentation velocity to extract thermodynamic linkage. Biophys Chem. 2011 Nov; 159(1):120-8. PMID: 21703752.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  16. Haithcock J, Billington N, Choi K, Fordham J, Sellers JR, Stafford WF, White H, Forgacs E. The kinetic mechanism of mouse myosin VIIA. J Biol Chem. 2011 Mar 18; 286(11):8819-28. PMID: 21212272.
    Citations: 13     Fields:    Translation:AnimalsCells
  17. Hayes DB, Stafford WF. SEDVIEW, real-time sedimentation analysis. Macromol Biosci. 2010 Jul 07; 10(7):731-5. PMID: 20593366.
    Citations: 11     Fields:    
  18. Mabuchi Y, Mabuchi K, Stafford WF, Grabarek Z. Modular structure of smooth muscle Myosin light chain kinase: hydrodynamic modeling and functional implications. Biochemistry. 2010 Apr 06; 49(13):2903-17. PMID: 20196616.
    Citations: 9     Fields:    Translation:AnimalsCells
  19. Hayes D, Napoli V, Mazurkie A, Stafford WF, Graceffa P. Phosphorylation dependence of hsp27 multimeric size and molecular chaperone function. J Biol Chem. 2009 Jul 10; 284(28):18801-7. PMID: 19411251.
    Citations: 60     Fields:    Translation:AnimalsCells
  20. Correia JJ, Alday PH, Sherwood P, Stafford WF. Effect of kinetics on sedimentation velocity profiles and the role of intermediates. Methods Enzymol. 2009; 467:135-161. PMID: 19897092.
    Citations: 4     Fields:    
  21. Correia JJ, Stafford WF. Extracting equilibrium constants from kinetically limited reacting systems. Methods Enzymol. 2009; 455:419-46. PMID: 19289215.
    Citations: 18     Fields:    Translation:Cells
  22. Stafford WF. Protein-protein and ligand-protein interactions studied by analytical ultracentrifugation. Methods Mol Biol. 2009; 490:83-113. PMID: 19157080.
    Citations: 13     Fields:    Translation:Cells
  23. Houmeida A, Baron A, Keen J, Khan GN, Knight PJ, Stafford WF, Thirumurugan K, Thompson B, Tskhovrebova L, Trinick J. Evidence for the oligomeric state of 'elastic' titin in muscle sarcomeres. J Mol Biol. 2008 Dec 12; 384(2):299-312. PMID: 18824175.
    Citations: 13     Fields:    Translation:AnimalsCells
  24. Meinke G, Ezeokonkwo C, Balbo P, Stafford W, Moore C, Bohm A. Structure of yeast poly(A) polymerase in complex with a peptide from Fip1, an intrinsically disordered protein. Biochemistry. 2008 Jul 01; 47(26):6859-69. PMID: 18537269.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  25. Adams GP, Tai MS, McCartney JE, Marks JD, Stafford WF, Houston LL, Huston JS, Weiner LM. Avidity-mediated enhancement of in vivo tumor targeting by single-chain Fv dimers. Clin Cancer Res. 2006 Mar 01; 12(5):1599-605. PMID: 16533787.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  26. Knight PJ, Thirumurugan K, Xu Y, Wang F, Kalverda AP, Stafford WF, Sellers JR, Peckham M. The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head. J Biol Chem. 2005 Oct 14; 280(41):34702-8. PMID: 16030012.
    Citations: 84     Fields:    Translation:AnimalsCells
  27. Mukhopadhyay S, Langsetmo K, Stafford WF, Henry GD, Baleja JD, Sarkar S. Identification of a region of fast skeletal troponin T required for stabilization of the coiled-coil formation with troponin I. J Biol Chem. 2005 Jan 07; 280(1):538-47. PMID: 15507453.
    Citations: 2     Fields:    Translation:HumansCells
  28. Stafford WF, Walker ML, Trinick JA, Coluccio LM. Mammalian class I myosin, Myo1b, is monomeric and cross-links actin filaments as determined by hydrodynamic studies and electron microscopy. Biophys J. 2005 Jan; 88(1):384-91. PMID: 15475577; PMCID: PMC1305015.
    Citations: 4     Fields:    Translation:AnimalsCells
  29. Gelinas AD, Toth J, Bethoney KA, Stafford WF, Harrison CJ. Mutational analysis of the energetics of the GrpE.DnaK binding interface: equilibrium association constants by sedimentation velocity analytical ultracentrifugation. J Mol Biol. 2004 May 28; 339(2):447-58. PMID: 15136046.
    Citations: 5     Fields:    Translation:Cells
  30. Stafford WF, Braswell EH. Sedimentation velocity, multi-speed method for analyzing polydisperse solutions. Biophys Chem. 2004 Mar 01; 108(1-3):273-9. PMID: 15043935.
    Citations: 13     Fields:    
  31. Correia JJ, Johnson ML, Laue T, Stafford WF, Williams RC. Spinning with Dave: David Yphantis's contributions to ultracentrifugation. Biophys Chem. 2004 Mar 01; 108(1-3):23-42. PMID: 15043919.
    Citations:    Fields:    Translation:Humans
  32. Stafford WF, Sherwood PJ. Analysis of heterologous interacting systems by sedimentation velocity: curve fitting algorithms for estimation of sedimentation coefficients, equilibrium and kinetic constants. Biophys Chem. 2004 Mar 01; 108(1-3):231-43. PMID: 15043932.
    Citations: 127     Fields:    
  33. Frickel EM, Frei P, Bouvier M, Stafford WF, Helenius A, Glockshuber R, Ellgaard L. ERp57 is a multifunctional thiol-disulfide oxidoreductase. J Biol Chem. 2004 Apr 30; 279(18):18277-87. PMID: 14871896.
    Citations: 62     Fields:    Translation:HumansCells
  34. Wang F, Thirumurugan K, Stafford WF, Hammer JA, Knight PJ, Sellers JR. Regulated conformation of myosin V. J Biol Chem. 2004 Jan 23; 279(4):2333-6. PMID: 14634000.
    Citations: 71     Fields:    Translation:AnimalsCells
  35. Gelinas AD, Toth J, Bethoney KA, Langsetmo K, Stafford WF, Harrison CJ. Thermodynamic linkage in the GrpE nucleotide exchange factor, a molecular thermosensor. Biochemistry. 2003 Aug 05; 42(30):9050-9. PMID: 12885238.
    Citations: 3     Fields:    Translation:Cells
  36. Stafford W. Analytical ultracentrifugation: sedimentation velocity analysis. Curr Protoc Protein Sci. 2003 May; Chapter 20:Unit 20.7. PMID: 18429240.
    Citations: 2     Fields:    
  37. Terrak M, Wu G, Stafford WF, Lu RC, Dominguez R. Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications. EMBO J. 2003 Feb 03; 22(3):362-71. PMID: 12554638; PMCID: PMC140742.
    Citations: 34     Fields:    Translation:AnimalsCells
  38. Mori T, Saveliev SV, Xu Y, Stafford WF, Cox MM, Inman RB, Johnson CH. Circadian clock protein KaiC forms ATP-dependent hexameric rings and binds DNA. Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26):17203-8. PMID: 12477935; PMCID: PMC139293.
    Citations: 74     Fields:    Translation:Cells
  39. Chen M, Stafford WF, Diedrich G, Khan A, Bouvier M. A characterization of the lumenal region of human tapasin reveals the presence of two structural domains. Biochemistry. 2002 Dec 10; 41(49):14539-45. PMID: 12463753.
    Citations: 4     Fields:    Translation:HumansCells
  40. Gelinas AD, Langsetmo K, Toth J, Bethoney KA, Stafford WF, Harrison CJ. A structure-based interpretation of E.coli GrpE thermodynamic properties. J Mol Biol. 2002 Oct 11; 323(1):131-42. PMID: 12368105.
    Citations: 8     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.