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Bruce Michael Cohen, M.D.,Ph.D.

Co-Author

This page shows the publications co-authored by Bruce Cohen and William Carlezon.
Connection Strength

5.007
  1. Carlezon WA, Béguin C, Knoll AT, Cohen BM. Kappa-opioid ligands in the study and treatment of mood disorders. Pharmacol Ther. 2009 Sep; 123(3):334-43.
    View in: PubMed
    Score: 0.451
  2. Cohen BM, Carlezon WA. Can't get enough of that dopamine. Am J Psychiatry. 2007 Apr; 164(4):543-6.
    View in: PubMed
    Score: 0.388
  3. Carlezon WA, Béguin C, DiNieri JA, Baumann MH, Richards MR, Todtenkopf MS, Rothman RB, Ma Z, Lee DY, Cohen BM. Depressive-like effects of the kappa-opioid receptor agonist salvinorin A on behavior and neurochemistry in rats. J Pharmacol Exp Ther. 2006 Jan; 316(1):440-7.
    View in: PubMed
    Score: 0.351
  4. Wells AM, Ridener E, Bourbonais CA, Kim W, Pantazopoulos H, Carroll FI, Kim KS, Cohen BM, Carlezon WA. Effects of Chronic Social Defeat Stress on Sleep and Circadian Rhythms Are Mitigated by Kappa-Opioid Receptor Antagonism. J Neurosci. 2017 08 09; 37(32):7656-7668.
    View in: PubMed
    Score: 0.198
  5. Dow AL, Lin TV, Chartoff EH, Potter D, McPhie DL, Van't Veer AV, Knoll AT, Lee KN, Neve RL, Patel TB, Ongur D, Cohen BM, Carlezon WA. Sprouty2 in the dorsal hippocampus regulates neurogenesis and stress responsiveness in rats. PLoS One. 2015; 10(3):e0120693.
    View in: PubMed
    Score: 0.169
  6. Öngür D, Bechtholt AJ, Carlezon WA, Cohen BM. Glial abnormalities in mood disorders. Harv Rev Psychiatry. 2014 Nov-Dec; 22(6):334-7.
    View in: PubMed
    Score: 0.164
  7. Van't Veer A, Bechtholt AJ, Onvani S, Potter D, Wang Y, Liu-Chen LY, Schütz G, Chartoff EH, Rudolph U, Cohen BM, Carlezon WA. Ablation of kappa-opioid receptors from brain dopamine neurons has anxiolytic-like effects and enhances cocaine-induced plasticity. Neuropsychopharmacology. 2013 Jul; 38(8):1585-97.
    View in: PubMed
    Score: 0.146
  8. Murphy BL, Stoll AL, Harris PQ, Ravichandran C, Babb SM, Carlezon WA, Cohen BM. Omega-3 fatty acid treatment, with or without cytidine, fails to show therapeutic properties in bipolar disorder: a double-blind, randomized add-on clinical trial. J Clin Psychopharmacol. 2012 Oct; 32(5):699-703.
    View in: PubMed
    Score: 0.142
  9. Van't Veer A, Yano JM, Carroll FI, Cohen BM, Carlezon WA. Corticotropin-releasing factor (CRF)-induced disruption of attention in rats is blocked by the ?-opioid receptor antagonist JDTic. Neuropsychopharmacology. 2012 Dec; 37(13):2809-16.
    View in: PubMed
    Score: 0.141
  10. Béguin C, Potter DN, Carlezon WA, Stöhr T, Cohen BM. Effects of the anticonvulsant lacosamide compared to valproate and lamotrigine on cocaine-enhanced reward in rats. Brain Res. 2012 Oct 15; 1479:44-51.
    View in: PubMed
    Score: 0.141
  11. Munro TA, Berry LM, Van't Veer A, Béguin C, Carroll FI, Zhao Z, Carlezon WA, Cohen BM. Long-acting ? opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity. BMC Pharmacol. 2012 May 29; 12:5.
    View in: PubMed
    Score: 0.139
  12. Béguin C, Potuzak J, Xu W, Liu-Chen LY, Streicher JM, Groer CE, Bohn LM, Carlezon WA, Cohen BM. Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues. Bioorg Med Chem Lett. 2012 Jan 15; 22(2):1023-6.
    View in: PubMed
    Score: 0.134
  13. Bechtholt-Gompf AJ, Walther HV, Adams MA, Carlezon WA, Ongür D, Cohen BM. Blockade of astrocytic glutamate uptake in rats induces signs of anhedonia and impaired spatial memory. Neuropsychopharmacology. 2010 Sep; 35(10):2049-59.
    View in: PubMed
    Score: 0.121
  14. Nemeth CL, Paine TA, Rittiner JE, Béguin C, Carroll FI, Roth BL, Cohen BM, Carlezon WA. Role of kappa-opioid receptors in the effects of salvinorin A and ketamine on attention in rats. Psychopharmacology (Berl). 2010 Jun; 210(2):263-74.
    View in: PubMed
    Score: 0.120
  15. Béguin C, Duncan KK, Munro TA, Ho DM, Xu W, Liu-Chen LY, Carlezon WA, Cohen BM. Modification of the furan ring of salvinorin A: identification of a selective partial agonist at the kappa opioid receptor. Bioorg Med Chem. 2009 Feb 01; 17(3):1370-80.
    View in: PubMed
    Score: 0.109
  16. Renshaw PF, Parsegian A, Yang CK, Novero A, Yoon SJ, Lyoo IK, Cohen BM, Carlezon WA. Lovastatin potentiates the antidepressant efficacy of fluoxetine in rats. Pharmacol Biochem Behav. 2009 Mar; 92(1):88-92.
    View in: PubMed
    Score: 0.108
  17. Tomasiewicz HC, Todtenkopf MS, Chartoff EH, Cohen BM, Carlezon WA. The kappa-opioid agonist U69,593 blocks cocaine-induced enhancement of brain stimulation reward. Biol Psychiatry. 2008 Dec 01; 64(11):982-8.
    View in: PubMed
    Score: 0.106
  18. Chartoff EH, Potter D, Damez-Werno D, Cohen BM, Carlezon WA. Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats. Neuropsychopharmacology. 2008 Oct; 33(11):2676-87.
    View in: PubMed
    Score: 0.102
  19. Meloni EG, Reedy CL, Cohen BM, Carlezon WA. Activation of raphe efferents to the medial prefrontal cortex by corticotropin-releasing factor: correlation with anxiety-like behavior. Biol Psychiatry. 2008 May 01; 63(9):832-9.
    View in: PubMed
    Score: 0.102
  20. Béguin C, Potter DN, Dinieri JA, Munro TA, Richards MR, Paine TA, Berry L, Zhao Z, Roth BL, Xu W, Liu-Chen LY, Carlezon WA, Cohen BM. N-methylacetamide analog of salvinorin A: a highly potent and selective kappa-opioid receptor agonist with oral efficacy. J Pharmacol Exp Ther. 2008 Jan; 324(1):188-95.
    View in: PubMed
    Score: 0.101
  21. Ongür D, Pohlman J, Dow AL, Eisch AJ, Edwin F, Heckers S, Cohen BM, Patel TB, Carlezon WA. Electroconvulsive seizures stimulate glial proliferation and reduce expression of Sprouty2 within the prefrontal cortex of rats. Biol Psychiatry. 2007 Sep 01; 62(5):505-12.
    View in: PubMed
    Score: 0.097
  22. Munro TA, Duncan KK, Staples RJ, Xu W, Liu-Chen LY, Béguin C, Carlezon WA, Cohen BM. 8-epi-Salvinorin B: crystal structure and affinity at the kappa opioid receptor. Beilstein J Org Chem. 2007 Jan 09; 3:1.
    View in: PubMed
    Score: 0.096
  23. Lee DY, He M, Liu-Chen LY, Wang Y, Li JG, Xu W, Ma Z, Carlezon WA, Cohen B. Synthesis and in vitro pharmacological studies of new C(4)-modified salvinorin A analogues. Bioorg Med Chem Lett. 2006 Nov 01; 16(21):5498-502.
    View in: PubMed
    Score: 0.093
  24. Meloni EG, Jackson A, Gerety LP, Cohen BM, Carlezon WA. Role of the bed nucleus of the stria terminalis (BST) in the expression of conditioned fear. Ann N Y Acad Sci. 2006 Jul; 1071:538-41.
    View in: PubMed
    Score: 0.092
  25. Béguin C, Richards MR, Li JG, Wang Y, Xu W, Liu-Chen LY, Carlezon WA, Cohen BM. Synthesis and in vitro evaluation of salvinorin A analogues: effect of configuration at C(2) and substitution at C(18). Bioorg Med Chem Lett. 2006 Sep 01; 16(17):4679-85.
    View in: PubMed
    Score: 0.092
  26. Tomasiewicz HC, Mague SD, Cohen BM, Carlezon WA. Behavioral effects of short-term administration of lithium and valproic acid in rats. Brain Res. 2006 Jun 06; 1093(1):83-94.
    View in: PubMed
    Score: 0.091
  27. Meloni EG, Gerety LP, Knoll AT, Cohen BM, Carlezon WA. Behavioral and anatomical interactions between dopamine and corticotropin-releasing factor in the rat. J Neurosci. 2006 Apr 05; 26(14):3855-63.
    View in: PubMed
    Score: 0.091
  28. Lee DY, He M, Kondaveti L, Liu-Chen LY, Ma Z, Wang Y, Chen Y, Li JG, Beguin C, Carlezon WA, Cohen B. Synthesis and in vitro pharmacological studies of C(4) modified salvinorin A analogues. Bioorg Med Chem Lett. 2005 Oct 01; 15(19):4169-73.
    View in: PubMed
    Score: 0.087
  29. Lee DY, Ma Z, Liu-Chen LY, Wang Y, Chen Y, Carlezon WA, Cohen B. New neoclerodane diterpenoids isolated from the leaves of Salvia divinorum and their binding affinities for human kappa opioid receptors. Bioorg Med Chem. 2005 Oct 01; 13(19):5635-9.
    View in: PubMed
    Score: 0.087
  30. Lee DY, Karnati VV, He M, Liu-Chen LY, Kondaveti L, Ma Z, Wang Y, Chen Y, Beguin C, Carlezon WA, Cohen B. Synthesis and in vitro pharmacological studies of new C(2) modified salvinorin A analogues. Bioorg Med Chem Lett. 2005 Aug 15; 15(16):3744-7.
    View in: PubMed
    Score: 0.087
  31. Meloni EG, Jackson AV, Cohen BM, Carlezon WA. Corticotropin-releasing factor from the rat brain measured by protein immunoblot. Peptides. 2005 Nov; 26(11):2252-6.
    View in: PubMed
    Score: 0.086
  32. Béguin C, Richards MR, Wang Y, Chen Y, Liu-Chen LY, Ma Z, Lee DY, Carlezon WA, Cohen BM. Synthesis and in vitro pharmacological evaluation of salvinorin A analogues modified at C(2). Bioorg Med Chem Lett. 2005 Jun 02; 15(11):2761-5.
    View in: PubMed
    Score: 0.086
  33. Carlezon WA, Rohan ML, Mague SD, Meloni EG, Parsegian A, Cayetano K, Tomasiewicz HC, Rouse ED, Cohen BM, Renshaw PF. Antidepressant-like effects of cranial stimulation within a low-energy magnetic field in rats. Biol Psychiatry. 2005 Mar 15; 57(6):571-6.
    View in: PubMed
    Score: 0.084
  34. Carlezon WA, Mague SD, Parow AM, Stoll AL, Cohen BM, Renshaw PF. Antidepressant-like effects of uridine and omega-3 fatty acids are potentiated by combined treatment in rats. Biol Psychiatry. 2005 Feb 15; 57(4):343-50.
    View in: PubMed
    Score: 0.084
  35. Carlezon WA, Pliakas AM, Parow AM, Detke MJ, Cohen BM, Renshaw PF. Antidepressant-like effects of cytidine in the forced swim test in rats. Biol Psychiatry. 2002 Jun 01; 51(11):882-9.
    View in: PubMed
    Score: 0.069
  36. Van't Veer A, Smith KL, Cohen BM, Carlezon WA, Bechtholt AJ. Kappa-opioid receptors differentially regulate low and high levels of ethanol intake in female mice. Brain Behav. 2016 09; 6(9):e00523.
    View in: PubMed
    Score: 0.046
  37. John CS, Sypek EI, Carlezon WA, Cohen BM, Öngür D, Bechtholt AJ. Blockade of the GLT-1 Transporter in the Central Nucleus of the Amygdala Induces both Anxiety and Depressive-Like Symptoms. Neuropsychopharmacology. 2015 Jun; 40(7):1700-8.
    View in: PubMed
    Score: 0.042
  38. Munro TA, Huang XP, Inglese C, Perrone MG, Van't Veer A, Carroll FI, Béguin C, Carlezon WA, Colabufo NA, Cohen BM, Roth BL. Selective ? opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters. PLoS One. 2013; 8(8):e70701.
    View in: PubMed
    Score: 0.038
  39. John CS, Smith KL, Van't Veer A, Gompf HS, Carlezon WA, Cohen BM, Öngür D, Bechtholt-Gompf AJ. Blockade of astrocytic glutamate uptake in the prefrontal cortex induces anhedonia. Neuropsychopharmacology. 2012 Oct; 37(11):2467-75.
    View in: PubMed
    Score: 0.035
  40. Potter DN, Damez-Werno D, Carlezon WA, Cohen BM, Chartoff EH. Repeated exposure to the ?-opioid receptor agonist salvinorin A modulates extracellular signal-regulated kinase and reward sensitivity. Biol Psychiatry. 2011 Oct 15; 70(8):744-53.
    View in: PubMed
    Score: 0.033
  41. Bechtholt-Gompf AJ, Smith KL, John CS, Kang HH, Carlezon WA, Cohen BM, Ongür D. CD-1 and Balb/cJ mice do not show enduring antidepressant-like effects of ketamine in tests of acute antidepressant efficacy. Psychopharmacology (Berl). 2011 Jun; 215(4):689-95.
    View in: PubMed
    Score: 0.032
  42. Munro TA, Duncan KK, Xu W, Wang Y, Liu-Chen LY, Carlezon WA, Cohen BM, Béguin C. Standard protecting groups create potent and selective kappa opioids: salvinorin B alkoxymethyl ethers. Bioorg Med Chem. 2008 Feb 01; 16(3):1279-86.
    View in: PubMed
    Score: 0.025
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.