Aleksandar David Kostic, Ph.D.
|Title||Member of the Faculty of Microbiology and Immunobiology|
|Institution||Joslin Diabetes Center|
|Department||Microbiology and Immunobiology|
|Address||Joslin Diabetes Center|
Rm. 4504A (Mezzanine)
One Joslin Place
Boston MA 02215
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|Title||Postdoctoral Research Fellow|
|Institution||Harvard T.H. Chan School of Public Health|
|Broad Institute of MIT & Harvard, Cambridge, MA||Postdoctoral Fellowship||08/2016||Microbiome-Immune Interfaces|
|Harvard University, Cambridge, MA||Ph.D.||05/2013||Biological & Biomedical Sciences|
|University of Toronto, Toronto, ON||Hon.B.Sc.||05/2008||Molecular Biology|
|2017 - 2022||Pathway to Stop Diabetes Initiator Award|
|2017 - 2019||Smith Family Awards Program for Excellence in Biomedical Research|
|2015 - 2016||Merck Fellow of the Helen Hay Whitney Foundation|
|2014 - 2016||The Lawrence H. Summers Postdoctoral Fellowship|
Our research combines computational and experimental expertise to probe the relationship between the human microbiome and type 1 diabetes. We strive to generate a high-level understanding of how the molecular interactions between the immune system and our indigenous microbiome regulate human health. We have worked to characterize the developing infant gut microbiome in dense, longitudinal metagenomic analyses of birth cohorts at risk for type 1 diabetes, including mechanistic evidence by which the human microbiome may directly influence immune development and progression to type 1 diabetes. The ultimate goal of our lab is to develop new methods to diagnose and treat type 1 diabetes by deepening our understanding of the immunomodulatory effects of the diverse constituents of the symbiotic microbiota and their impact on autoimmunity.
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