Harvard Catalyst Profiles

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Joshua Peter Klein, M.D., Ph.D.

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Other Positions
Title
Institution
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Biography
awards and honors
2005
International Student Delegate, Academy of Achievement
2009
Dr. Edison H. and Sallie Y. Miyawaki Neuroanatomy Teaching Award, HMS
2012
Faculty Teacher of the Year, BWH/MGH Neurology
2013
Partners in Excellence Team Award for Leadership in Neurology
2015
Fellow of the American Neurological Association (FANA)
2016
Fellow of the American Academy of Neurology (FAAN)
2016
Fellow of the American Society of Neuroimaging (FASN)
2017
Distinguished Clinician Award, BWH
2017
Visiting Professor, St. Luke's College of Medicine, Manila, Philippines
2019
Editor-in-Chief, "The Neurohospitalist" journal
2019
Adjunct Professor, Universidad de Ciencias Medicas de La Habana, Havana, Cuba
2019
Vice Chair, Clinical Affairs, BWH Department of Neurology

Overview
overview
Joshua P. Klein, MD, PhD, is a neurologist who specializes in hospital neurology and diagnostic neuroimaging. He is Vice Chair for Clinical Affairs and the founding Chief of the Division of Hospital Neurology in the Department of Neurology at Brigham and Women's Hospital.

Dr. Klein graduated with honors from the University of Pennsylvania (1997) and then from the Medical Scientist Training Program (MD/PhD) at Yale University School of Medicine (2005). He is a 2009 graduate of the Harvard (BWH/MGH) Neurology Residency Program where he served as Chief Resident in his final year. He then completed a fellowship in Diagnostic Neuroradiology at BWH, and is board certified in both Neurology (ABPN) and Neuroimaging (UCNS).

Dr. Klein is Secretary of the American Society of Neuroimaging and a member of the Board of Directors of the Neurohospitalist Society. He is a frequent invited lecturer at national and international conferences and has published across many areas of clinical neurology including neuroinflammatory disease, traumatic brain injury, and neurotoxicity related to cancer therapy. With Allan H. Ropper and Martin A. Samuels he co-authored the 10th and 11th Editions of the textbook “Adams and Victor's Principles of Neurology”.
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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Klimaj Z, Klein JP, Szatmary G. Cranial Nerve Imaging and Pathology. Neurol Clin. 2020 Feb; 38(1):115-147. PMID: 31761055.
    Citations:    
  2. Regenhardt RW, Biseko MR, Shayo AF, Mmbando TN, Grundy SJ, Xu A, Saadi A, Wibecan L, Kharal GA, Parker R, Klein JP, Mateen FJ, Okeng'o K. Opportunities for intervention: stroke treatments, disability and mortality in urban Tanzania. Int J Qual Health Care. 2019 Jun 01; 31(5):385-392. PMID: 30165650.
    Citations:    Fields:    
  3. Klein JP. A Message From the Editor in Chief. Neurohospitalist. 2019 Apr; 9(2):57. PMID: 30915181.
    Citations:    
  4. Probasco JC, Greene J, Harrison A, Jensen J, Khot S, Klein JP, Simpson J, Wold J, Josephson SA, Likosky D. Neurohospitalist Practice, Perspectives, and Burnout. Neurohospitalist. 2019 Apr; 9(2):85-92. PMID: 30915186.
    Citations:    
  5. Williamson C, Morgan L, Klein JP. Imaging in Neurocritical Care Practice. Semin Respir Crit Care Med. 2017 12; 38(6):840-852. PMID: 29262441.
    Citations:    Fields:    Translation:Humans
  6. Dietrich J, Winter SF, Klein JP. Neuroimaging of Brain Tumors: Pseudoprogression, Pseudoresponse, and Delayed Effects of Chemotherapy and Radiation. Semin Neurol. 2017 10; 37(5):589-596. PMID: 29207418.
    Citations:    Fields:    Translation:HumansPHPublic Health
  7. Klein JP. Neuroimaging. Semin Neurol. 2017 10; 37(5):483-484. PMID: 29207409.
    Citations:    Fields:    Translation:Humans
  8. Klein JP, Dietrich J. Neuroradiologic Pearls for Neuro-oncology. Continuum (Minneap Minn). 2017 12; 23(6, Neuro-oncology):1619-1634. PMID: 29200114.
    Citations:    Fields:    Translation:Humans
  9. Izzy S, Mazwi NL, Martinez S, Spencer CA, Klein JP, Parikh G, Glenn MB, Greenberg SM, Greer DM, Wu O, Edlow BL. Revisiting Grade 3 Diffuse Axonal Injury: Not All Brainstem Microbleeds are Prognostically Equal. Neurocrit Care. 2017 Oct; 27(2):199-207. PMID: 28477152.
    Citations: 1     Fields:    Translation:Humans
  10. Saadi A, Klein JP. Bow Hunter's Syndrome. Neurohospitalist. 2018 Jul; 8(3):160. PMID: 29977450.
    Citations:    
  11. Talmasov D, Klein JP. Neuroimaging, electroencephalography, and lumbar puncture in medical psychiatry. In "Medical Psychiatry", Ed. DA Silbersweig (in press). 2017.
  12. Sattarnezhad N, Klein JP. Imaging. In "Neurorheumatology: a comprehensive guide to immune mediated disorders of the nervous system", Ed. Bhattacharyya S, Cho TA (in press) . 2017.
  13. Koelman DLH, Benkeser DC, Klein JP, Mateen FJ. Acute disseminated encephalomyelitis: prognostic value of early follow-up brain MRI. J Neurol. 2017 Aug; 264(8):1754-1762. PMID: 28695361.
    Citations: 1     Fields:    Translation:Humans
  14. Bruno V, Klein JP, Nidup D, Nirola DK, Tshering L, Deki S, Clark SJ, Linn KA, Shinohara RT, Dorji C, Pokhrel DR, Dema U, Mateen FJ. Yield of Brain MRI in Clinically Diagnosed Epilepsy in the Kingdom of Bhutan: A Prospective Study. Ann Glob Health. 2017 May - Aug; 83(3-4):415-422. PMID: 29221514.
    Citations:    Fields:    Translation:Humans
  15. Bhattacharyya S, Gholipour T, Colorado RA, Klein JP. Bilateral Hippocampal Restricted Diffusion: Same Picture Many Causes. J Neuroimaging. 2017 05; 27(3):300-305. PMID: 28054736.
    Citations: 2     Fields:    Translation:Humans
  16. Klein JP. Weakness: how to localize the problem. Chapter 106 in "Principles and Practice of Hospital Medicine" 2nd Edition, Ed. McKean SC. 2017.
  17. Klein JP. Sarcoidosis, tuberculosis, and demyelinating disease. Chapter 165 in "Youmans and Winn Neurological Surgery" 7th Edition, Ed. Winn HR (in press). 2016; 1366-72.
  18. Klein JP, Stover DG, Oxnard GR, Levy BD, Loscalzo J. Restoring Balance: Paraneoplastic Cerebellar Degeneration. Am J Med. 2017 Mar; 130(3):e85-e87. PMID: 27816447.
    Citations:    Fields:    Translation:Humans
  19. Pinter NK, Klein JP, Mechtler LL. Potential Safety Issues Related to the Use of Gadolinium-based Contrast Agents. Continuum (Minneap Minn). 2016 Oct; 22(5, Neuroimaging):1678-1684. PMID: 27740994.
    Citations:    Fields:    Translation:HumansAnimals
  20. Singh K, Mechtler LL, Klein JP. Imaging of Spinal Cord Disorders. Continuum (Minneap Minn). 2016 Oct; 22(5, Neuroimaging):1595-1612. PMID: 27740990.
    Citations:    Fields:    Translation:Humans
  21. Baig MA, Klein JP, Mechtler LL. Imaging of Brain Tumors. Continuum (Minneap Minn). 2016 Oct; 22(5, Neuroimaging):1529-1552. PMID: 27740987.
    Citations:    Fields:    Translation:Humans
  22. Brizzi K, Pelden S, Tshokey T, Nirola DK, Diamond MB, Klein JP, Tshering L, Deki S, Nidup D, Bruno V, Dorny P, Garcia HH, Mateen FJ. Neurocysticercosis in Bhutan: a cross-sectional study in people with epilepsy. Trans R Soc Trop Med Hyg. 2016 09; 110(9):517-526. PMID: 27794094.
    Citations: 1     Fields:    Translation:HumansAnimals
  23. Levin SN, de Gusmao CM, Etherton MR, Will Rondeau M, Meredith DM, Folkerth RD, Klein JP, Nadeem O, Castillo JJ. "All the soarings of my mind begin in my blood:" central nervous system complication of Waldenström macroglobulinemia. Am J Hematol. 2016 Oct; 91(10):1057-60. PMID: 27414991.
    Citations:    Fields:    Translation:Humans
  24. Wong J, Bhattacharyya S, Klein JP. Back. In "Clinical Anatomy Cases: An Integrated Approach with Physical Examination and Medical Imaging". 2016.
  25. Koelman DL, Chahin S, Mar SS, Venkatesan A, Hoganson GM, Yeshokumar AK, Barreras P, Majmudar B, Klein JP, Chitnis T, Benkeser DC, Carone M, Mateen FJ. Acute disseminated encephalomyelitis in 228 patients: A retrospective, multicenter US study. Neurology. 2016 May 31; 86(22):2085-93. PMID: 27164698.
    Citations: 6     Fields:    Translation:Humans
  26. Olsen AL, Miller JJ, Bhattacharyya S, Voinescu PE, Klein JP. Cerebral perfusion in stroke-like migraine attacks after radiation therapy syndrome. Neurology. 2016 Feb 23; 86(8):787-9. PMID: 26819456.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  27. Klein JP. Imaging of progressive weakness or numbness of central or peripheral origin. Handb Clin Neurol. 2016; 136:923-37. PMID: 27430450.
    Citations:    Fields:    Translation:Humans
  28. Klein JP. Imaging of noninfectious inflammatory disorders of the spinal cord. Handb Clin Neurol. 2016; 136:733-46. PMID: 27430439.
    Citations:    Fields:    Translation:Humans
  29. Johnson EL, Yuskaitis CJ, Rondeau MW, Klein JP. A Tangled Web. Neurohospitalist. 2015 Oct; 5(4):253-4. PMID: 26425254.
    Citations:    
  30. Klein JP. The academic neurohospitalist: Building a successful career and practice. Ann Neurol. 2015 Oct; 78(4):515-9. PMID: 26179680.
    Citations:    Fields:    Translation:Humans
  31. McKee K, Nelson S, Batra A, Klein JP, Henderson GV. Diving into the Ice Bucket Challenge: Intraparenchymal Hemorrhage and the Mammalian Diving Reflex. Neurohospitalist. 2015 Jul; 5(3):182-4. PMID: 26288676.
    Citations:    
  32. Klein JP. Lumboperitoneal Shunting for Normal Pressure Hydrocephalus. Journal Watch Neurology. 2015; 17(8):60-1.
  33. Neagu MR, Raibagkar P, Lyons JL, Klein JP. Imaging in Neurologic Infections II: Fungal and Viral Diseases. Curr Infect Dis Rep. 2015 Apr; 17(4):474. PMID: 25870142.
    Citations:    
  34. Klein JP. A practical approach to spine imaging. Continuum (Minneap Minn). 2015 Feb; 21(1 Spinal Cord Disorders):36-51. PMID: 25651216.
    Citations:    Fields:    Translation:HumansAnimals
  35. Raibagkar P, Neagu MR, Lyons JL, Klein JP. Imaging in neurologic infections I: bacterial and parasitic diseases. Curr Infect Dis Rep. 2014 Dec; 16(12):443. PMID: 25348741.
    Citations:    
  36. Prasad S, Lee TC, Chiocca EA, Klein JP. Superficial greater petrosal neuropathy. Neurol Clin Pract. 2014 Dec; 4(6):505-507. PMID: 29443140.
    Citations:    
  37. Narendra DP, Wang N, Erkkinen MG, Jagadeesan J, Lee TC, Zimmerman EE, Klein JP. An anomalous developmental venous anomaly. Neurology. 2014 Sep 09; 83(11):1033-4. PMID: 25200715.
    Citations:    Fields:    Translation:Humans
  38. Prasad S, Lee TC, Chiocca EA, Klein JP. Superficial greater petrosal neuropathy. Neurol Clin Pract. 2014; 4(6):505-7.
  39. Ropper AH, Samuels MA, Klein JP. "Adams and Victor's Principles of Neurology", 10th Edition. 2014. View Publication.
  40. Snider SB, Jacobs CS, Scripko PS, Klein JP, Lyons JL. Hemorrhagic and ischemic stroke secondary to herpes simplex virus type 2 meningitis and vasculopathy. J Neurovirol. 2014 Aug; 20(4):419-22. PMID: 24806272.
    Citations: 5     Fields:    Translation:HumansCells
  41. Cai X, Bhattacharyya S, Plitt A, Raibagkar P, LaBuzetta JN, Schleicher SM, Munshi NC, Klein JP. Management of Posterior Reversible Encephalopathy Syndrome Induced by Carfilzomib in a Patient With Multiple Myeloma. J Clin Oncol. 2016 Jan 10; 34(2):e1-5. PMID: 24799479.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  42. Bhattacharyya S, Cai X, Klein JP. Dyscalculia, dysgraphia, and left-right confusion from a left posterior peri-insular infarct. Behav Neurol. 2014; 2014:823591. PMID: 24817791.
    Citations: 3     Fields:    Translation:Humans
  43. Klein JP. Editor, Neurology. In "Pocket Primary Care: A Massachusetts General Hospital Handbook", Ed. Kiefer MM and Chong CR. 2014.
  44. Bove RM, Klein JP. Neuroradiology in women of childbearing age. Continuum (Minneap Minn). 2014 Feb; 20(1 Neurology of Pregnancy):23-41. PMID: 24492809.
    Citations: 3     Fields:    Translation:Humans
  45. Bega D, Wang N, Klein JP. Reversible palinacousis from intracranial metastases. Neurohospitalist. 2014 Jan; 4(1):22-5. PMID: 24381707.
    Citations: 1     
  46. Dietrich J, Klein JP. Imaging of cancer therapy-induced central nervous system toxicity. Neurol Clin. 2014 Feb; 32(1):147-57. PMID: 24287388.
    Citations: 1     Fields:    Translation:Humans
  47. Edlow BL, Haynes RL, Takahashi E, Klein JP, Cummings P, Benner T, Greer DM, Greenberg SM, Wu O, Kinney HC, Folkerth RD. Disconnection of the ascending arousal system in traumatic coma. J Neuropathol Exp Neurol. 2013 Jun; 72(6):505-23. PMID: 23656993.
    Citations: 24     Fields:    Translation:Humans
  48. Lyons JL, Neagu MR, Norton IH, Klein JP. Diffusion tensor imaging in brainstem tuberculoma. J Clin Neurosci. 2013 Nov; 20(11):1598-9. PMID: 23707604.
    Citations: 2     Fields:    Translation:Humans
  49. Awosika OO, Lyons JL, Ciarlini P, Phillips RE, Alfson ED, Johnson EL, Koo S, Marty F, Drew C, Zaki S, Folkerth RD, Klein JP. Fatal adenovirus encephalomyeloradiculitis in an umbilical cord stem cell transplant recipient. Neurology. 2013 Apr 30; 80(18):1715-7. PMID: 23596062.
    Citations: 1     Fields:    Translation:Humans
  50. Vodopivec I, Klein JP, Prasad S. Bilateral cervical internal carotid artery dissections in Eagle syndrome. Neurol Clin Pract. 2013; 3:173-4.
  51. Vodopivec I, Klein JP, Prasad S. Bilateral cervical internal carotid artery dissections in Eagle syndrome. Neurol Clin Pract. 2013 Apr; 3(2):173-174. PMID: 29473623.
    Citations:    
  52. Wahlster S, Berkowitz AL, Zepeda R, Sagar VI, Lyons JL, Klein JP, Mejia N. Neurology and global health: Initiatives led by residents and staff from the Partners Neurology Program. Proceedings of the Annual Meeting of the American Academy of Neurology, San Diego, CA. 2013.
  53. Espinosa PS, Falcone N, Fee D, Swartz K, Del Pozo PE, Ryan S, Laccheo I, Berkowitz AL, Torres A, Bayas A, Paciorkowski A, Cash SS, Dvorquez D, Ortiz-Prado E, Salazar-Uribe JC, Klein JP, Lyons JL, Wahlster S, Cambi F, Vazquez B, Baumann R, Dworetzky BA. Decreasing the epilepsy treatment gap in the developing world: the epilepsy medical mission to the Amazon rain forest in Tena, Ecuador Report 2009-2012. Proceedings of the Annual Meeting of the American Academy of Neurology, San Diego, CA. 2013.
  54. Klein JP, Stankiewicz JM. Student self assessment in a neurology clerkship. Proceedings of the Annual Meeting of the American Academy of Neurology, San Diego, CA. 2013.
  55. Berkowitz AL, Jha RM, Klein JP, Amato AA. Clinical reasoning: an 85-year-old man with paresthesias and an unsteady gait. Neurology. 2013 Mar 19; 80(12):e120-6. PMID: 23509052.
    Citations:    Fields:    Translation:Humans
  56. Ravi A, Rao VR, Klein JP. Dystextia: acute stroke in the modern age. JAMA Neurol. 2013 Mar 01; 70(3):404-5. PMID: 23599944.
    Citations: 2     Fields:    Translation:Humans
  57. Klein JP. On the role of screening for intracranial aneurysms in autosomal dominant polycystic kidney disease. AJNR Am J Neuroradiol. 2013 Aug; 34(8):1560-1. PMID: 23436055.
    Citations: 1     Fields:    Translation:Humans
  58. Jha RM, Klein JP. Clinical anatomy and imaging of the cranial nerves and skull base. Semin Neurol. 2012 Sep; 32(4):332-46. PMID: 23361480.
    Citations:    Fields:    Translation:HumansAnimals
  59. Velez-Ruiz NJ, Klein JP. Neuroimaging in the evaluation of epilepsy. Semin Neurol. 2012 Sep; 32(4):361-73. PMID: 23361482.
    Citations: 5     Fields:    Translation:HumansAnimals
  60. Klein JP. Diagnostic neuroimaging. Semin Neurol. 2012 Sep; 32(4):271-2. PMID: 23361477.
    Citations:    Fields:    Translation:Humans
  61. Jha RM, Berkowitz AL, Klein JP. Evolution of hypoxic-ischemic injury. Neurohospitalist. 2013 Jan; 3(1):46. PMID: 23983887.
    Citations:    
  62. Mallery RM, Klein JP, Pless ML. Isolated sixth nerve palsy from hemorrhage of a pontine cavernous malformation. J Neuroophthalmol. 2012 Dec; 32(4):335-7. PMID: 22743823.
    Citations:    Fields:    Translation:Humans
  63. Mackay DD, Diamond EL, Klein JP. Widespread intracerebral metastases from prostate adenocarcinoma. Pract Neurol. 2012 Aug; 12(4):257-8. PMID: 22869771.
    Citations:    Fields:    Translation:Humans
  64. Jindal JA, Seidman MA, Klein JP. A 48-year-old man with syncope and diffuse muscle twitches. Neurohospitalist. 2012 Jul; 2(3):107-11. PMID: 23983873.
    Citations:    
  65. Wood BR, Klein JP, Lyons JL, Milner DA, Phillips RE, Schutten M, Folkerth RD, Ciarlini P, Henrich TJ, Johnson JA. HIV-2 encephalitis: case report and literature review. AIDS Patient Care STDS. 2012 Jul; 26(7):383-7. PMID: 22694171.
    Citations: 2     Fields:    Translation:HumansCells
  66. Klein JP. Neuroimaging for the clinician. In "ACP Medicine, a publication of the American College of Physicians", Ed. Nabel EG. 2012.
  67. Lyons JL, Scripko PD, Mukerji SS, Awosika O, Shieh WJ, Zaki S, DeLeon-Carnes M, Taylor C, Milner D, Johnson JA, Klein JP. Propionibacterium acnes brain abscess in a patient with HIV-1 infection. J Neurovirol. 2012 Apr; 18(2):148-50. PMID: 22403028.
    Citations: 2     Fields:    Translation:HumansCells
  68. Bianchi MT, Klein JP, Caviness VS, Cash SS. Synchronizing bench and bedside: A clinical overview of networks and oscillations. In "Network Approaches to Diseases of the Brain: Clinical Applications in Neurology and Psychiatry", Ed. Matt T. Bianchi, Verne S. Caviness, Sydney S. Cash. 2012.
  69. Klein JP, Hsu L. Neuroimaging during pregnancy. Semin Neurol. 2011 Sep; 31(4):361-73. PMID: 22113508.
    Citations: 2     Fields:    Translation:HumansAnimals
  70. Cvetanovich GL, Ramakrishnan P, Klein JP, Rao VR, Ropper AH. Reversible cerebral vasoconstriction syndrome in a patient taking citalopram and Hydroxycut: a case report. J Med Case Rep. 2011 Nov 10; 5:548. PMID: 22074635.
    Citations: 3     Fields:    
  71. Klein JP, Arora A, Neema M, Healy BC, Tauhid S, Goldberg-Zimring D, Chavarro-Nieto C, Stankiewicz JM, Cohen AB, Buckle GJ, Houtchens MK, Ceccarelli A, Dell'Oglio E, Guttmann CR, Alsop DC, Hackney DB, Bakshi R. A 3T MR imaging investigation of the topography of whole spinal cord atrophy in multiple sclerosis. AJNR Am J Neuroradiol. 2011 Jun-Jul; 32(6):1138-42. PMID: 21527570.
    Citations: 11     Fields:    Translation:Humans
  72. Klein JP, Stankiewicz JM. Evaluator unfamiliarity is common and can affect medical student assessment. Proceedings of the Annual Meeting of the American Academy of Neurology, Honolulu, HI. 2011.
  73. Cohen AB, Neema M, Arora A, Dell'oglio E, Benedict RH, Tauhid S, Goldberg-Zimring D, Chavarro-Nieto C, Ceccarelli A, Klein JP, Stankiewicz JM, Houtchens MK, Buckle GJ, Alsop DC, Guttmann CR, Bakshi R. The relationships among MRI-defined spinal cord involvement, brain involvement, and disability in multiple sclerosis. J Neuroimaging. 2012 Apr; 22(2):122-8. PMID: 21447024.
    Citations: 28     Fields:    Translation:HumansCells
  74. Klein JP. Demyelination vs. tumor infiltration in the brainstem. Journal Watch Neurology. 2010; 12(11):81. View Publication.
  75. Cohen AB, Klein JP, Mukundan S. A guide to imaging for common neurological problems. BMJ. 2010 Aug 16; 341:c4113. PMID: 20713584.
    Citations:    Fields:    Translation:Humans
  76. Cohen AB, Klein JP. Neuro-ophthalmology. In "Pocket Neurology", Ed. Greer DM. 2010; 285-301.
  77. Klein JP, Cohen AB. Neuroimaging. In "Pocket Neurology", Ed. Greer DM. 2010; 13-34.
  78. Klein JP. Diffusion-weighted imaging in normal pressure hydrocephalus. Journal Watch Neurology. 2010; 12(3):21-22. View Publication.
  79. Krishnaswamy A, Klein JP, Kapadia SR. Clinical cerebrovascular anatomy. Catheter Cardiovasc Interv. 2010 Mar 01; 75(4):530-9. PMID: 20049963.
    Citations: 6     Fields:    Translation:Humans
  80. Klein JP, Arora A, Neema M, Healy BC, Tauhid S, Goldberg-Zimring D, Chavarro-Nieto C, Stankiewicz JM, Cohen AB, Buckle GJ, Houtchens MK, Ceccarelli A, Dell'Oglio E, Guttmann CRG, Bakshi R. A 3T MRI investigation of the topography of whole spinal cord atrophy in multiple sclerosis. Program No. P03.111. Proceedings of the Annual Meeting of the American Academy of Neurology, Toronto, Ontario, CA. 2010. View Publication.
  81. Klein JP, Ryther RC. Images in clinical medicine. Central nervous system hemorrhage. N Engl J Med. 2009 Oct 29; 361(18):1786. PMID: 19864677.
    Citations:    Fields:    Translation:Humans
  82. Klein JP, Cohen AB, Kimberly WT, Shah AS, Leiderman YI, Cestari DM, Dinkin MJ. Diffusion-weighted magnetic resonance imaging of bilateral simultaneous optic nerve infarctions. Arch Neurol. 2009 Jan; 66(1):132-3. PMID: 19139313.
    Citations: 4     Fields:    Translation:Humans
  83. Blumenfeld H, Lampert A, Klein JP, Mission J, Chen MC, Rivera M, Dib-Hajj S, Brennan AR, Hains BC, Waxman SG. Role of hippocampal sodium channel Nav1.6 in kindling epileptogenesis. Epilepsia. 2009 Jan; 50(1):44-55. PMID: 18637833.
    Citations: 40     Fields:    Translation:Animals
  84. Blumenfeld H, Klein JP, Schridde U, Vestal M, Rice T, Khera DS, Bashyal C, Giblin K, Paul-Laughinghouse C, Wang F, Phadke A, Mission J, Agarwal RK, Englot DJ, Motelow J, Nersesyan H, Waxman SG, Levin AR. Early treatment suppresses the development of spike-wave epilepsy in a rat model. Epilepsia. 2008 Mar; 49(3):400-9. PMID: 18070091.
    Citations: 50     Fields:    Translation:HumansAnimals
  85. Le T, Shivaram A, Klein J. First Aid Q&A for the USMLE Step 2 CK, 1st Edition. McGraw-Hill. 2007.
  86. Le T, Schabelman E, Shivaram A, Klein J. First Aid Cases for the USMLE Step 2 CK, 1st Edition. McGraw-Hill. 2006.
  87. Le T, Krause K, Klein J, Shivaram A. First Aid Q&A for the USMLE Step 1, 1st Edition. McGraw-Hill. 2006.
  88. Le T, Krause K, Klein J, Shivaram A. First Aid Cases for the USMLE Step 1, 1st Edition. McGraw-Hill. 2006.
  89. Klein JP, Kostina-O'Neil Y, Lesser RL. Neuro-ophthalmologic presentations of hemicrania continua. Am J Ophthalmol. 2006 Jan; 141(1):88-92. PMID: 16386981.
    Citations: 1     Fields:    Translation:Humans
  90. Klein JP, Schridde U, Nersesyan H, Agarwal RK, Levin AR, Waxman SG, Blumenfeld H. Seizure blockade with ethosuximide normalizes Nav1.1, Nav1.6, and HCN1 channel expression in epileptic WAG/Rij rats. Epilepsia 46 Suppl. 8:110 (Abstract 2.056, Washington, D.C.). 2005.
  91. Klein JP, Schridde U, Nersesyan H, Agarwal RK, Levin AR, Waxman SG, Blumenfeld H. The effect of seizure blockade with ethosuximide on sodium and HCN1 channel expression in the epileptic WAG/Rij rat brain. Program No. 357.6. Society for Neuroscience Annual Meeting, Washington D.C. 2005.
  92. Klein JP. Activity-dependent modulation of neuronal sodium channel expression. Yale University Ph.D. Dissertation. 2004.
  93. Hains BC, Saab CY, Klein JP, Craner MJ, Waxman SG. Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury. J Neurosci. 2004 May 19; 24(20):4832-9. PMID: 15152043.
    Citations: 55     Fields:    Translation:AnimalsCells
  94. Klein JP, Khera DS, Nersesyan H, Kimchi EY, Waxman SG, Blumenfeld H. Dysregulation of sodium channel expression in cortical neurons in a rodent model of absence epilepsy. Brain Res. 2004 Mar 12; 1000(1-2):102-9. PMID: 15053958.
    Citations: 33     Fields:    Translation:AnimalsCells
  95. Klein JP, Hains BC, Craner MJ, Black JA, Waxman SG. Apoptosis of vasopressinergic hypothalamic neurons in chronic diabetes mellitus. Neurobiol Dis. 2004 Mar; 15(2):221-8. PMID: 15006692.
    Citations: 9     Fields:    Translation:AnimalsCells
  96. Bhushan V, Le T, Klein J, Shivaram A. First Aid for the USMLE Step 1, 14th Edition. McGraw-Hill. 2004.
  97. Klein JP, Tendi EA, Dib-Hajj SD, Fields RD, Waxman SG. Patterned electrical activity modulates sodium channel expression in sensory neurons. J Neurosci Res. 2003 Oct 15; 74(2):192-8. PMID: 14515348.
    Citations: 9     Fields:    Translation:AnimalsCells
  98. Hains BC, Klein JP, Saab CY, Craner MJ, Black JA, Waxman SG. Upregulation of sodium channel Nav1.3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury. J Neurosci. 2003 Oct 01; 23(26):8881-92. PMID: 14523090.
    Citations: 89     Fields:    Translation:AnimalsCells
  99. Klein JP, Waxman SG. The brain in diabetes: molecular changes in neurons and their implications for end-organ damage. Lancet Neurol. 2003 Sep; 2(9):548-54. PMID: 12941577.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  100. Klein JP, Jean-Baptiste M, Thompson JL, Bowers MB. A case report of hypomania following vagus nerve stimulation for refractory epilepsy. J Clin Psychiatry. 2003 Apr; 64(4):485. PMID: 12716259.
    Citations:    Fields:    Translation:Humans
  101. Klein JP, Khera DS, Nersesyan H, Kimchi EY, Waxman SG, Blumenfeld H. Dysregulation of sodium channel expression in cortical neurons in a rodent model of absence epilepsy. Epilepsia 44 Suppl. 9:192 (Abstract 2.049, Boston, MA). 2003. View Publication.
  102. Klein JP, Khera DS, Nersesyan H, Kimchi EY, Waxman SG, Blumenfeld H. Voltage-gated sodium channels Nav1.1 and Nav1.6 are overexpressed in cortical neurons in the absence epileptic WAG/Rij rat. Program No. 442.2. Society for Neuroscience Annual Meeting, New Orleans, LA. 2003. View Publication.
  103. Craner MJ, Klein JP, Renganathan M, Black JA, Waxman SG. Changes of sodium channel expression in experimental painful diabetic neuropathy. Ann Neurol. 2002 Dec; 52(6):786-92. PMID: 12447933.
    Citations: 36     Fields:    Translation:Animals
  104. Craner MJ, Klein JP, Black JA, Waxman SG. Preferential expression of IGF-I in small DRG neurons and down-regulation following injury. Neuroreport. 2002 Sep 16; 13(13):1649-52. PMID: 12352620.
    Citations: 15     Fields:    Translation:AnimalsCells
  105. Klein JP, Craner MJ, Cummins TR, Black JA, Waxman SG. Sodium channel expression in hypothalamic osmosensitive neurons in experimental diabetes. Neuroreport. 2002 Aug 07; 13(11):1481-4. PMID: 12167778.
    Citations: 3     Fields:    Translation:AnimalsCells
  106. Shahabi S, Klein JP, Rinaudo PF. Primary psoas abscess complicating a normal vaginal delivery. Obstet Gynecol. 2002 May; 99(5 Pt 2):906-9. PMID: 11975954.
    Citations: 2     Fields:    Translation:Humans
  107. Klein JP, Craner MJ, Cummins TR, Black JA, Waxman SG. Diabetes induces changes in sodium channel expression in hypothalamic osmosensitive neurons. Program No. 835.10. Society for Neuroscience Annual Meeting, Orlando, FL. 2002. View Publication.
  108. Klein JP, Leete TH, Rubin H. A biomolecular implementation of logically reversible computation with minimal energy dissipation. Biosystems. 1999 Oct; 52(1-3):15-23. PMID: 10636026.
    Citations: 2     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.