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Anna Sara Oberg, M.D.

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Karolinska Institutet, Stockholm, SwedenMD06/2002Medicine
Karolinska Institutet, Stockholm, SwedenPhD06/2011Medical Science
Harvard T.H. Chan School of Public Health, Boston, USAMPH06/2009Quantitative Methods

Dr Anna Sara Oberg is an adjunct Associate Professor in the Department of Epidemiology at the Harvard T.H. Chan School of Public Health, with primary affiliation in the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet. Interested in the causes and consequences of reproductive challenges, her research spans across the whole the range of sensitive periods from pre-conception through pregnancy up to labour and delivery, and concerns the health of both mother and child. Current efforts center on the safety of assisted reproductive practices, through long-term evaluations of children, and more recently the influence on women's cardiovascular health. Dr Oberg is additionally leading an effort to enable and improve the use of national registers to study prescribed drug use in relation to reproduction, through a new extensive linkage and advanced methods of data extraction that will allow more detailed exposure characterisation. As the first curriculum fellow in the online/on-campus MPH in Epidemiology Dr Oberg was closely involved in the program development and launch in 2015, and she has since continued to contribute as an instructor in Analytic Methods for Epidemiologists and as a member on the Practicum Committee.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 2020-00753 (Oberg) Jan 1, 2021 - Dec 30, 2023
    Forte (Swedish Research Council for Health, Working Life and Welfare
    Nationwide mapping of the use of fertility drugs and their impact on women’s cardiovascular health
    Role Description: The goal is to characterize the use of fertility drugs in Sweden and comprehensively evaluate their relation to women’s risk of thromboembolic and cardiovascular disease.
    Role: Principa Investigator
  2. R01DA048042 (D'ONOFRIO, BRIAN M) Apr 1, 2019 - Feb 28, 2022
    Maternal use of prescribed opioid analgesics and risk of adverse offspring outcomes
    Role: Co-Principal Investigator
  3. R01DA048042-01 (D'Onofrio/Oberg) Mar 1, 2019 - Feb 28, 2022
    Maternal use of prescribed opioid analgesics in pregnancy and risk of adverse offspring outcomes
    Role Description: The goal is to advance understanding of the use and safety of prescribed opioids in pregnancy, focusing on adverse birth outcomes and offspring neurodevelopment, using Swedish population (register) data
    Role: Principal Investigator (shared)
  4. 2018-02679 (Oberg) Jan 1, 2019 - Dec 31, 2021
    Swedish Research Council
    Prescribed opioid analgesics during pregnancy and risk for adverse birth outcomes and neurodevelopmental problems in offspring
    Role Description: The goal is to identify psychosocial predictors of maternal use of opioid analgesics in pregnancy, and to evaluate the extent such may be responsible for observed associations to offspring adverse outcomes.
    Role: Co-Investigator turned Principal Investigator
  5. R01HD088393 (Hsu/Hernandez-Diaz/Hernan) Sep 2, 2017 - Nov 30, 2022
    Long Term Impact of Fertility Treatments (LIFT) Study
    Role Description: The goal is to examine the long-term impact on children born from fertility treatments including assisted reproductive technology (ART) using data from Denmark, the Netherlands, Sweden, and the United States
    Role: Co-Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wang C, Johansson ALV, Rodriguez-Wallberg KA, Landén M, Almqvist C, Hernández-Díaz S, Oberg AS. Long-term Follow-up of Psychiatric Disorders in Children and Adolescents Conceived by Assisted Reproductive Techniques in Sweden. JAMA Psychiatry. 2022 02 01; 79(2):133-142. PMID: 34910092.
    Citations:    Fields:    Translation:Humans
  2. Brew BK, Lundholm C, Caffrey Osvald E, Chambers G, Öberg S, Fang F, Almqvist C. Early-Life Adversity Due to Bereavement and Inflammatory Diseases in the Next Generation: A Population Study in Transgenerational Stress Exposure. Am J Epidemiol. 2022 01 01; 191(1):38-48. PMID: 34550338.
    Citations: 1     Fields:    Translation:Humans
  3. Sujan AC, O'Reilly LM, Rickert ME, Larsson H, Lichtenstein P, Oberg AS, D'Onofrio BM. A Nation-Wide Swedish Cohort Study on Early Maternal Age at First Childbirth and Risk for Offspring Deaths, Accidents, and Suicide Attempts. Behav Genet. 2022 Jan; 52(1):38-47. PMID: 34762227.
    Citations:    Fields:    
  4. Sjolander A, Frisell T, Oberg AS. Sibling comparison studies. Annual Review of Statistics and Its Application. 2021.
  5. Wang C, Johansson ALV, Rodriguez-Wallberg KA, Almqvist C, Hernández-Díaz S, Oberg AS. Assisted Reproductive Techniques, ADHD, and School Performance. Pediatrics. 2021 07; 148(1). PMID: 34172555.
    Citations: 1     Fields:    Translation:Humans
  6. Brynolf A, Zhao J, Wikman A, Öberg S, Sandström A, Edgren G. Patterns of red-cell transfusion use in obstetric practice in sweden 2003-2017: A nationwide study. Vox Sang. 2021 Aug; 116(7):821-830. PMID: 33528029.
    Citations:    Fields:    Translation:Humans
  7. Sujan AC, Quinn PD, Rickert ME, Wiggs KK, Larsson H, Lichtenstein P, Öberg AS, D'Onofrio BM. A nation-wide Swedish study of opioid analgesic prescribing patterns during pregnancy and associated preexisting mental health conditions. J Matern Fetal Neonatal Med. 2021 Jan 13; 1-7. PMID: 33441038.
    Citations:    Fields:    
  8. Sujan AC, Rickert ME, Quinn PD, Ludema C, Wiggs KK, Larsson H, Lichtenstein P, Almqvist C, Öberg AS, D'Onofrio BM. A population-based study of concurrent prescriptions of opioid analgesic and selective serotonin reuptake inhibitor medications during pregnancy and risk for adverse birth outcomes. Paediatr Perinat Epidemiol. 2021 03; 35(2):184-193. PMID: 33350491.
    Citations:    Fields:    Translation:Humans
  9. Wiggs KK, Rickert ME, Sujan AC, Quinn PD, Larsson H, Lichtenstein P, Oberg AS, D'Onofrio BM. Antiseizure medication use during pregnancy and risk of ASD and ADHD in children. Neurology. 2020 12 15; 95(24):e3232-e3240. PMID: 33115775.
    Citations: 5     Fields:    Translation:Humans
  10. Li L, Sujan AC, Butwicka A, Chang Z, Cortese S, Quinn P, Viktorin A, Öberg AS, D'Onofrio BM, Larsson H. Associations of Prescribed ADHD Medication in Pregnancy with Pregnancy-Related and Offspring Outcomes: A Systematic Review. CNS Drugs. 2020 07; 34(7):731-747. PMID: 32333292.
    Citations: 2     Fields:    Translation:HumansAnimals
  11. D'Onofrio BM, Sjölander A, Lahey BB, Lichtenstein P, Öberg AS. Accounting for Confounding in Observational Studies. Annu Rev Clin Psychol. 2020 05 07; 16:25-48. PMID: 32384000.
    Citations: 7     Fields:    Translation:Humans
  12. Sujan AC, Quinn PD, Rickert ME, Wiggs KK, Lichtenstein P, Larsson H, Almqvist C, Öberg AS, D'Onofrio BM. Maternal prescribed opioid analgesic use during pregnancy and associations with adverse birth outcomes: A population-based study. PLoS Med. 2019 12; 16(12):e1002980. PMID: 31790390.
    Citations: 9     Fields:    Translation:Humans
  13. Rejnö G, Lundholm C, Öberg S, Lichtenstein P, Larsson H, D'Onofrio B, Larsson K, Saltvedt S, Brew BK, Almqvist C. Maternal anxiety, depression and asthma and adverse pregnancy outcomes - a population based study. Sci Rep. 2019 09 11; 9(1):13101. PMID: 31511586.
    Citations: 11     Fields:    Translation:Humans
  14. Iliadou AN, Öberg AS, Pege J, Rodriguez-Wallberg KA, Olofsson JI, Holte J, Wramsby H, Wramsby M, Cnattingius S, Cesta CE. The Uppsala-Stockholm Assisted Reproductive Techniques (UppStART) study. BMJ Open. 2019 08 28; 9(8):e028866. PMID: 31467051.
    Citations: 1     Fields:    Translation:HumansCells
  15. Margulis AV, Hernandez-Diaz S, McElrath T, Rothman KJ, Plana E, Almqvist C, D'Onofrio BM, Oberg AS. Relation of in-utero exposure to antiepileptic drugs to pregnancy duration and size at birth. PLoS One. 2019; 14(8):e0214180. PMID: 31381574.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  16. Cesta CE, Öberg AS, Ibrahimson A, Yusuf I, Larsson H, Almqvist C, D'Onofrio BM, Bulik CM, Fernández de la Cruz L, Mataix-Cols D, Landén M, Rosenqvist MA. Maternal polycystic ovary syndrome and risk of neuropsychiatric disorders in offspring: prenatal androgen exposure or genetic confounding? Psychol Med. 2020 03; 50(4):616-624. PMID: 30857571.
    Citations: 21     Fields:    Translation:Humans
  17. Sujan AC, Öberg AS, Quinn PD, D'Onofrio BM. Annual Research Review: Maternal antidepressant use during pregnancy and offspring neurodevelopmental problems - a critical review and recommendations for future research. J Child Psychol Psychiatry. 2019 04; 60(4):356-376. PMID: 30515808.
    Citations: 9     Fields:    Translation:HumansAnimals
  18. Class QA, Rickert ME, Larsson H, Öberg AS, Sujan AC, Almqvist C, Lichtenstein P, D'Onofrio BM. Outcome-dependent associations between short interpregnancy interval and offspring psychological and educational problems: a population-based quasi-experimental study. Int J Epidemiol. 2018 08 01; 47(4):1159-1168. PMID: 29566153.
    Citations: 4     Fields:    Translation:Humans
  19. Oberg AS, VanderWeele TJ, Almqvist C, Hernandez-Diaz S. Pregnancy complications following fertility treatment-disentangling the role of multiple gestation. Int J Epidemiol. 2018 08 01; 47(4):1333-1342. PMID: 29939263.
    Citations: 10     Fields:    Translation:Humans
  20. Class QA, Rickert ME, Oberg AS, Sujan AC, Almqvist C, Larsson H, Lichtenstein P, D'Onofrio BM. Within-Family Analysis of Interpregnancy Interval and Adverse Birth Outcomes. Obstet Gynecol. 2017 12; 130(6):1304-1311. PMID: 29112654.
    Citations: 16     Fields:    Translation:Humans
  21. Wiggs KK, Rickert ME, Hernandez-Diaz S, Bateman BT, Almqvist C, Larsson H, Lichtenstein P, Oberg AS, D'Onofrio BM. A Family-Based Study of the Association Between Labor Induction and Offspring Attention-Deficit Hyperactivity Disorder and Low Academic Achievement. Behav Genet. 2017 07; 47(4):383-393. PMID: 28551761.
    Citations: 2     Fields:    Translation:Humans
  22. Sujan AC, Rickert ME, Öberg AS, Quinn PD, Hernández-Díaz S, Almqvist C, Lichtenstein P, Larsson H, D'Onofrio BM. Associations of Maternal Antidepressant Use During the First Trimester of Pregnancy With Preterm Birth, Small for Gestational Age, Autism Spectrum Disorder, and Attention-Deficit/Hyperactivity Disorder in Offspring. JAMA. 2017 04 18; 317(15):1553-1562. PMID: 28418479.
    Citations: 62     Fields:    Translation:HumansPHPublic Health
  23. Sjölander A, Frisell T, Kuja-Halkola R, Öberg S, Zetterqvist J. Carryover Effects in Sibling Comparison Designs. Epidemiology. 2016 11; 27(6):852-8. PMID: 27488059.
    Citations: 29     Fields:    Translation:Humans
  24. Oberg AS, D'Onofrio BM, Rickert ME, Hernandez-Diaz S, Ecker JL, Almqvist C, Larsson H, Lichtenstein P, Bateman BT. Association of Labor Induction With Offspring Risk of Autism Spectrum Disorders. JAMA Pediatr. 2016 09 06; 170(9):e160965. PMID: 27454803.
    Citations: 12     Fields:    Translation:Humans
  25. D'Onofrio BM, Class QA, Rickert ME, Sujan AC, Larsson H, Kuja-Halkola R, Sjölander A, Almqvist C, Lichtenstein P, Oberg AS. Translational Epidemiologic Approaches to Understanding the Consequences of Early-Life Exposures. Behav Genet. 2016 05; 46(3):315-28. PMID: 26590988.
    Citations: 15     Fields:    Translation:Humans
  26. Chen L, Cnattingius S, Nyman Iliadou A, Oberg AS. Cancer risks in twins and singletons from twin and non-twin families. Int J Cancer. 2016 Mar 01; 138(5):1102-10. PMID: 26414953.
    Citations: 1     Fields:    Translation:Humans
  27. Sujan AC, Rickert ME, Class QA, Coyne CA, Lichtenstein P, Almqvist C, Larsson H, Sjölander A, Lahey BB, van Hulle C, Waldman I, Öberg AS, D'Onofrio BM. A Genetically Informed Study of the Associations Between Maternal Age at Childbearing and Adverse Perinatal Outcomes. Behav Genet. 2016 05; 46(3):431-56. PMID: 26404627.
    Citations: 2     Fields:    Translation:Humans
  28. Hernandez-Diaz S, Oberg AS. Are epidemiological approaches suitable to study risk/preventive factors for human birth defects? Curr Epidemiol Rep. 2015 Mar; 2(1):31-36. PMID: 25722958.
    Citations: 1     
  29. Oberg AS, Bateman BT. Authors' reply to Sholapurkar. BMJ. 2014 Oct 14; 349:g6210. PMID: 25316117.
    Citations:    Fields:    Translation:Humans
  30. Bateman BT, Huybrechts KF, Fischer MA, Seely EW, Ecker JL, Oberg AS, Franklin JM, Mogun H, Hernandez-Diaz S. Chronic hypertension in pregnancy and the risk of congenital malformations: a cohort study. Am J Obstet Gynecol. 2015 Mar; 212(3):337.e1-14. PMID: 25265405.
    Citations: 22     Fields:    Translation:Humans
  31. Oberg AS, Hernandéz-Diaz S, Frisell T, Greene MF, Almqvist C, Bateman BT. Genetic contribution to postpartum haemorrhage in Swedish population: cohort study of 466,686 births. BMJ. 2014 Aug 13; 349:g4984. PMID: 25121825.
    Citations: 5     Fields:    Translation:Humans
  32. Almqvist C, Oberg AS. The association between caesarean section and asthma or allergic disease continues to challenge. Acta Paediatr. 2014 Apr; 103(4):349-51. PMID: 24628103.
    Citations: 2     Fields:    Translation:Humans
  33. Hajiebrahimi M, Bahmanyar S, Öberg S, Iliadou AN, Cnattingius S. Breast cancer risk in opposite-sexed twins: influence of birth weight and co-twin birth weight. J Natl Cancer Inst. 2013 Dec 04; 105(23):1833-6. PMID: 24231452.
    Citations: 1     Fields:    Translation:Humans
  34. Oberg AS, Hernandez-Diaz S, Palmsten K, Almqvist C, Bateman BT. Patterns of recurrence of postpartum hemorrhage in a large population-based cohort. Am J Obstet Gynecol. 2014 Mar; 210(3):229.e1-8. PMID: 24351791.
    Citations: 17     Fields:    Translation:Humans
  35. Oberg AS, Frisell T, Svensson AC, Iliadou AN. Maternal and fetal genetic contributions to postterm birth: familial clustering in a population-based sample of 475,429 Swedish births. Am J Epidemiol. 2013 Mar 15; 177(6):531-7. PMID: 23425630.
    Citations: 15     Fields:    Translation:Humans
  36. Högberg L, Lundholm C, Cnattingius S, Oberg S, Iliadou AN. Birthweight discordant female twins and their offspring: is the intergenerational influence on birthweight due to genes or environment? Hum Reprod. 2013 Feb; 28(2):480-7. PMID: 23087023.
    Citations: 5     Fields:    Translation:Humans
  37. Frisell T, Öberg S, Kuja-Halkola R, Sjölander A. Sibling comparison designs: bias from non-shared confounders and measurement error. Epidemiology. 2012 Sep; 23(5):713-20. PMID: 22781362.
    Citations: 175     Fields:    Translation:Humans
  38. Sjölander A, Frisell T, Oberg S. Causal interpretation of between-within models for twin studies. Epidemiologic Methods. 2012; 4(41):1002-1009.
  39. Oberg AS, Villamor E. Low digit ratio predicts early age at menarche in Colombian schoolgirls. Paediatr Perinat Epidemiol. 2012 Sep; 26(5):448-55. PMID: 22882789.
    Citations: 6     Fields:    Translation:Humans
  40. Öberg S, Cnattingius S, Sandin S, Lichtenstein P, Morley R, Iliadou AN. Twinship influence on morbidity and mortality across the lifespan. Int J Epidemiol. 2012 Aug; 41(4):1002-9. PMID: 22576952.
    Citations: 20     Fields:    Translation:HumansPHPublic Health
  41. Svensson AC, Lichtenstein P, Sandin S, Öberg S, Sullivan PF, Hultman CM. Familial aggregation of schizophrenia: the moderating effect of age at onset, parental immigration, paternal age and season of birth. Scand J Public Health. 2012 Feb; 40(1):43-50. PMID: 21930618.
    Citations: 10     Fields:    Translation:Humans
  42. Oberg S, Cnattingius S, Sandin S, Lichtenstein P, Iliadou AN. Birth weight predicts risk of cardiovascular disease within dizygotic but not monozygotic twin pairs: a large population-based co-twin-control study. Circulation. 2011 Jun 21; 123(24):2792-8. PMID: 21632494.
    Citations: 13     Fields:    Translation:Humans
  43. Oberg S, Cnattingius S, Sandin S, Lichtenstein P, Iliadou A. Birth weight-breast cancer revisited: is the association confounded by familial factors? Cancer Epidemiol Biomarkers Prev. 2009 Sep; 18(9):2447-52. PMID: 19690178.
    Citations: 7     Fields:    Translation:Humans
  44. Oberg S, Ge D, Cnattingius S, Svensson A, Treiber FA, Snieder H, Iliadou A. Ethnic differences in the association of birth weight and blood pressure: the Georgia cardiovascular twin study. Am J Hypertens. 2007 Dec; 20(12):1235-41. PMID: 18047911.
    Citations: 7     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.