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Charles Andrew Czeisler, M.D., Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01GM105018 (KLERMAN, ELIZABETH B.) Jul 18, 2013 - Mar 31, 2018
    NIH/NIGMS
    Multi-scale modeling of sleep behaviors in social networks
    Role: Principal Investigator
  2. U01HL111478 (CZEISLER, CHARLES A) Sep 15, 2012 - May 31, 2017
    NIH/NHLBI
    Multi-Center Trial of Limiting PGY2&3 Resident Work Hours on Patient Safety-CCC
    Role: Principal Investigator
  3. R01HL094654 (CZEISLER, CHARLES A) Jul 1, 2010 - Jun 30, 2014
    NIH/NHLBI
    Sensitization of Human Circadian Responses to Light
    Role: Principal Investigator
  4. P30HL101299 (CZEISLER, CHARLES A) Sep 30, 2009 - Aug 31, 2012
    NIH/NHLBI
    New Faculty in Sleep Medicine
    Role: Principal Investigator
  5. R01HL093279 (CZEISLER, CHARLES A) May 1, 2009 - Apr 30, 2014
    NIH/NHLBI
    Efficacy of melatonin treatment in a phase advance model of insomnia
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Swanson CM, Shea SA, Kohrt WM, Wright KP, Cain SW, Munch M, Vujovic N, Czeisler CA, Orwoll ES, Buxton OM. Sleep Restriction With Circadian Disruption Negatively Alter Bone Turnover Markers in Women. J Clin Endocrinol Metab. 2020 Jul 01; 105(7). PMID: 32364602.
    Citations:    
  2. Czeisler MÉ, Tynan MA, Howard ME, Honeycutt S, Fulmer EB, Kidder DP, Robbins R, Barger LK, Facer-Childs ER, Baldwin G, Rajaratnam SMW, Czeisler CA. Public Attitudes, Behaviors, and Beliefs Related to COVID-19, Stay-at-Home Orders, Nonessential Business Closures, and Public Health Guidance - United States, New York City, and Los Angeles, May 5-12, 2020. MMWR Morb Mortal Wkly Rep. 2020 Jun 19; 69(24):751-758. PMID: 32555138.
    Citations:    
  3. Fischer D, McHill AW, Sano A, Picard RW, Barger LK, Czeisler CA, Klerman EB, Phillips AJK. Irregular sleep and event schedules are associated with poorer self-reported well-being in US college students. Sleep. 2020 Jun 15; 43(6). PMID: 31837266.
    Citations:    
  4. Yuan RK, Zitting KM, Wang W, Buxton OM, Williams JS, Duffy JF, Czeisler CA. Fasting blood triglycerides vary with circadian phase in both young and older people. Physiol Rep. 2020 Jun; 8(11):e14453. PMID: 32519460.
    Citations:    
  5. Azarbarzin A, Younes M, Sands SA, Wellman A, Redline S, Czeisler CA, Gottlieb DJ. Interhemispheric sleep depth coherence predicts driving safety in sleep apnea. J Sleep Res. 2020 May 22; e13092. PMID: 32441843.
    Citations:    
  6. Burks SV, Anderson JE, Panda B, Haider R, Ginader T, Sandback N, Pokutnaya D, Toso D, Hughes N, Haider HS, Brockman R, Toll A, Solberg N, Eklund J, Cagle M, Hickman JS, Mabry E, Berger M, Czeisler CA, Kales SN. Employer-mandated obstructive sleep apnea treatment and healthcare cost savings among truckers. Sleep. 2020 Apr 15; 43(4). PMID: 31648298.
    Citations:    
  7. Burks SV, Anderson JE, Panda B, Haider HS, Haider R, Shi D, Li Y, Cagle M, Ostroushko D, Sun Z, Zaharick J, Hickman J, Mabry E, Berger M, Czeisler C, Kales SN. The Pre-Registry Commercial Driver Medical Examination: Screening Sensitivity and Certification Lengths for Two Safety-Related Medical Conditions. J Occup Environ Med. 2020 Mar; 62(3):237-245. PMID: 31977920.
    Citations:    
  8. Weaver MD, Landrigan CP, Sullivan JP, O'Brien CS, Qadri S, Viyaran N, Wang W, Vetter C, Czeisler CA, Barger LK. The Association Between Resident Physician Work-Hour Regulations and Physician Safety and Health. Am J Med. 2020 Feb 13. PMID: 32061733.
    Citations:    
  9. Grant LK, Gooley JJ, St Hilaire MA, Rajaratnam SMW, Brainard GC, Czeisler CA, Lockley SW, Rahman SA. Menstrual phase-dependent differences in neurobehavioral performance: the role of temperature and the progesterone/estradiol ratio. Sleep. 2020 Feb 13; 43(2). PMID: 31670824.
    Citations:    
  10. Rahman SA, Wright KP, Lockley SW, Czeisler CA, Gronfier C. Characterizing the temporal Dynamics of Melatonin and Cortisol Changes in Response to Nocturnal Light Exposure. Sci Rep. 2019 12 23; 9(1):19720. PMID: 31873098.
    Citations:    
  11. Peterson SA, Wolkow AP, Lockley SW, O'Brien CS, Qadri S, Sullivan JP, Czeisler CA, Rajaratnam SMW, Barger LK. Associations between shift work characteristics, shift work schedules, sleep and burnout in North American police officers: a cross-sectional study. BMJ Open. 2019 12 01; 9(11):e030302. PMID: 31791964.
    Citations:    
  12. Rahman SA, Grant LK, Gooley JJ, Rajaratnam SMW, Czeisler CA, Lockley SW. Endogenous Circadian Regulation of Female Reproductive Hormones. J Clin Endocrinol Metab. 2019 12 01; 104(12):6049-6059. PMID: 31415086.
    Citations:    
  13. Stack N, Zeitzer JM, Czeisler C, Diniz Behn C. Estimating Representative Group Intrinsic Circadian Period from Illuminance-Response Curve Data. J Biol Rhythms. 2020 Apr; 35(2):195-206. PMID: 31779499.
    Citations:    
  14. St Hilaire MA, Kristal BS, Rahman SA, Sullivan JP, Quackenbush J, Duffy JF, Barger LK, Gooley JJ, Czeisler CA, Lockley SW. Using a Single Daytime Performance Test to Identify Most Individuals at High-Risk for Performance Impairment during Extended Wake. Sci Rep. 2019 11 13; 9(1):16681. PMID: 31723161.
    Citations:    
  15. Swanson CM, Kohrt WM, Wolfe P, Wright KP, Shea SA, Cain SW, Munch M, Vujovic N, Czeisler CA, Orwoll ES, Buxton OM. Rapid suppression of bone formation marker in response to sleep restriction and circadian disruption in men. Osteoporos Int. 2019 Dec; 30(12):2485-2493. PMID: 31446439.
    Citations:    
  16. Chua EC, Sullivan JP, Duffy JF, Klerman EB, Lockley SW, Kristal BS, Czeisler CA, Gooley JJ. Classifying attentional vulnerability to total sleep deprivation using baseline features of Psychomotor Vigilance Test performance. Sci Rep. 2019 08 20; 9(1):12102. PMID: 31431644.
    Citations:    
  17. Kronauer RE, St Hilaire MA, Rahman SA, Czeisler CA, Klerman EB. An Exploration of the Temporal Dynamics of Circadian Resetting Responses to Short- and Long-Duration Light Exposures: Cross-Species Consistencies and Differences. J Biol Rhythms. 2019 Oct; 34(5):497-514. PMID: 31368391.
    Citations:    
  18. Barger LK, Sullivan JP, Blackwell T, O'Brien CS, St Hilaire MA, Rahman SA, Phillips AJK, Qadri S, Wright KP, Segar JL, McGuire JK, Vitiello MV, de la Iglesia HO, Poynter SE, Yu PL, Zee P, Sanderson AL, Halbower AC, Lockley SW, Landrigan CP, Stone KL, Czeisler CA. Effects on resident work hours, sleep duration, and work experience in a randomized order safety trial evaluating resident-physician schedules (ROSTERS). Sleep. 2019 08 01; 42(8). PMID: 31106381.
    Citations:    
  19. Landrigan CP, Czeisler CA. Patient Safety under Flexible and Standard Duty-Hour Rules. N Engl J Med. 2019 06 13; 380(24):2379-2380. PMID: 31189044.
    Citations:    
  20. Wolkow AP, Barger LK, O'Brien CS, Sullivan JP, Qadri S, Lockley SW, Czeisler CA, Rajaratnam SMW. Associations between sleep disturbances, mental health outcomes and burnout in firefighters, and the mediating role of sleep during overnight work: A cross-sectional study. J Sleep Res. 2019 12; 28(6):e12869. PMID: 31131535.
    Citations:    
  21. McHill AW, Hull JT, Cohen DA, Wang W, Czeisler CA, Klerman EB. Chronic sleep restriction greatly magnifies performance decrements immediately after awakening. Sleep. 2019 05 01; 42(5). PMID: 30722039.
    Citations:    
  22. St Hilaire MA, Anderson C, Anwar J, Sullivan JP, Cade BE, Flynn-Evans EE, Czeisler CA, Lockley SW. Brief (<4 hr) sleep episodes are insufficient for restoring performance in first-year resident physicians working overnight extended-duration work shifts. Sleep. 2019 05 01; 42(5). PMID: 30794317.
    Citations:    
  23. Robbins R, Grandner MA, Buxton OM, Hale L, Buysse DJ, Knutson KL, Patel SR, Troxel WM, Youngstedt SD, Czeisler CA, Jean-Louis G. Sleep myths: an expert-led study to identify false beliefs about sleep that impinge upon population sleep health practices. Sleep Health. 2019 08; 5(4):409-417. PMID: 31003950.
    Citations:    
  24. Chang AM, Duffy JF, Buxton OM, Lane JM, Aeschbach D, Anderson C, Bjonnes AC, Cain SW, Cohen DA, Frayling TM, Gooley JJ, Jones SE, Klerman EB, Lockley SW, Munch M, Rajaratnam SMW, Rueger M, Rutter MK, Santhi N, Scheuermaier K, Van Reen E, Weedon MN, Czeisler CA, Scheer FAJL, Saxena R. Chronotype Genetic Variant in PER2 is Associated with Intrinsic Circadian Period in Humans. Sci Rep. 2019 03 29; 9(1):5350. PMID: 30926824.
    Citations:    
  25. Blackwell T, Kriesel DR, Vittinghoff E, O'Brien CS, Sullivan JP, Viyaran NC, Rahman SA, Lockley SW, Barger LK, Halbower AC, Poynter SE, Wright KP, Yu PL, Zee PC, Landrigan CP, Czeisler CA, Stone KL. Design and recruitment of the randomized order safety trial evaluating resident-physician schedules (ROSTERS) study. Contemp Clin Trials. 2019 05; 80:22-33. PMID: 30885799.
    Citations:    
  26. McHill AW, Czeisler CA, Phillips AJK, Keating L, Barger LK, Garaulet M, Scheer FAJL, Klerman EB. Caloric and Macronutrient Intake Differ with Circadian Phase and between Lean and Overweight Young Adults. Nutrients. 2019 03 11; 11(3). PMID: 30862011.
    Citations:    
  27. Rahman SA, Bibbo C, Olcese J, Czeisler CA, Robinson JN, Klerman EB. Relationship between endogenous melatonin concentrations and uterine contractions in late third trimester of human pregnancy. J Pineal Res. 2019 May; 66(4):e12566. PMID: 30739346.
    Citations:    
  28. Rhodes JA, Lane JM, Vlasac IM, Rutter MK, Czeisler CA, Saxena R. Association of DAT1 genetic variants with habitual sleep duration in the UK Biobank. Sleep. 2019 01 01; 42(1). PMID: 30299516.
    Citations:    Fields:    
  29. Vandewalle G, van Ackeren MJ, Daneault V, Hull JT, Albouy G, Lepore F, Doyon J, Czeisler CA, Dumont M, Carrier J, Lockley SW, Collignon O. Light modulates oscillatory alpha activity in the occipital cortex of totally visually blind individuals with intact non-image-forming photoreception. Sci Rep. 2018 11 16; 8(1):16968. PMID: 30446699.
    Citations:    Fields:    
  30. Zitting KM, Vujovic N, Yuan RK, Isherwood CM, Medina JE, Wang W, Buxton OM, Williams JS, Czeisler CA, Duffy JF. Human Resting Energy Expenditure Varies with Circadian Phase. Curr Biol. 2018 11 19; 28(22):3685-3690.e3. PMID: 30416064.
    Citations:    Fields:    
  31. Ogeil RP, Barger LK, Lockley SW, O'Brien CS, Sullivan JP, Qadri S, Lubman DI, Czeisler CA, Rajaratnam SMW. Cross-sectional analysis of sleep-promoting and wake-promoting drug use on health, fatigue-related error, and near-crashes in police officers. BMJ Open. 2018 09 19; 8(9):e022041. PMID: 30232109.
    Citations:    Fields:    
  32. Weaver MD, Vetter C, Rajaratnam SMW, O'Brien CS, Qadri S, Benca RM, Rogers AE, Leary EB, Walsh JK, Czeisler CA, Barger LK. Sleep disorders, depression and anxiety are associated with adverse safety outcomes in healthcare workers: A prospective cohort study. J Sleep Res. 2018 12; 27(6):e12722. PMID: 30069960.
    Citations:    Fields:    
  33. McHill AW, Czeisler CA, Shea SA. Resident physician extended work hours and burnout. Sleep. 2018 08 01; 41(8). PMID: 29901751.
    Citations:    Fields:    
  34. Vidafar P, Gooley JJ, Burns AC, Rajaratnam SMW, Rueger M, Van Reen E, Czeisler CA, Lockley SW, Cain SW. Increased vulnerability to attentional failure during acute sleep deprivation in women depends on menstrual phase. Sleep. 2018 08 01; 41(8). PMID: 29790961.
    Citations:    Fields:    
  35. Zitting KM, Münch MY, Cain SW, Wang W, Wong A, Ronda JM, Aeschbach D, Czeisler CA, Duffy JF. Young adults are more vulnerable to chronic sleep deficiency and recurrent circadian disruption than older adults. Sci Rep. 2018 07 23; 8(1):11052. PMID: 30038272.
    Citations:    Fields:    
  36. Quan SF, Ziporyn PS, Czeisler CA. Sleep Education for College Students: The Time Is Now. J Clin Sleep Med. 2018 07 15; 14(7):1269. PMID: 29991433.
    Citations: 1     Fields:    
  37. Czeisler CA. Housing Immigrant Children - The Inhumanity of Constant Illumination. N Engl J Med. 2018 Jul 12; 379(2):e3. PMID: 29932841.
    Citations:    Fields:    Translation:Humans
  38. McHill AW, Hull JT, Wang W, Czeisler CA, Klerman EB. Chronic sleep curtailment, even without extended (>16-h) wakefulness, degrades human vigilance performance. Proc Natl Acad Sci U S A. 2018 06 05; 115(23):6070-6075. PMID: 29784810.
    Citations:    Fields:    Translation:Humans
  39. Chinoy ED, Duffy JF, Czeisler CA. Unrestricted evening use of light-emitting tablet computers delays self-selected bedtime and disrupts circadian timing and alertness. Physiol Rep. 2018 05; 6(10):e13692. PMID: 29845764.
    Citations:    Fields:    
  40. Rahman SA, St Hilaire MA, Gronfier C, Chang AM, Santhi N, Czeisler CA, Klerman EB, Lockley SW. Functional decoupling of melatonin suppression and circadian phase resetting in humans. J Physiol. 2018 06; 596(11):2147-2157. PMID: 29707782.
    Citations: 2     Fields:    
  41. Hull JT, Czeisler CA, Lockley SW. Suppression of Melatonin Secretion in Totally Visually Blind People by Ocular Exposure to White Light: Clinical Characteristics. Ophthalmology. 2018 08; 125(8):1160-1171. PMID: 29625838.
    Citations: 1     Fields:    
  42. Gottlieb DJ, Ellenbogen JM, Bianchi MT, Czeisler CA. Sleep deficiency and motor vehicle crash risk in the general population: a prospective cohort study. BMC Med. 2018 03 20; 16(1):44. PMID: 29554902.
    Citations:    Fields:    Translation:Humans
  43. Stern HS, Blower D, Cohen ML, Czeisler CA, Dinges DF, Greenhouse JB, Guo F, Hanowski RJ, Hartenbaum NP, Krueger GP, Mallis MM, Pain RF, Rizzo M, Sinha E, Small DS, Stuart EA, Wegman DH. Data and methods for studying commercial motor vehicle driver fatigue, highway safety and long-term driver health. Accid Anal Prev. 2019 May; 126:37-42. PMID: 29530304.
    Citations:    Fields:    
  44. Anderson C, Ftouni S, Ronda JM, Rajaratnam SMW, Czeisler CA, Lockley SW. Self-reported Drowsiness and Safety Outcomes While Driving After an Extended Duration Work Shift in Trainee Physicians. Sleep. 2018 Feb 01; 41(2). PMID: 29281091.
    Citations:    Fields:    
  45. Williams JS, Autori PJ, Kidd SK, Piazza G, Connors MC, Czeisler CA, Scheuermaier KD, Duffy J, Klerman EB, Scheer FA, Kozak M, Driscoll SM, Goldhaber SZ. Heparin-Induced Thrombocytopenia in Healthy Individuals with Continuous Heparin Infusion. TH Open. 2018 Jan; 2(1):e49-e53. PMID: 31249929.
    Citations:    
  46. Liang Y, Horrey WJ, Howard ME, Lee ML, Anderson C, Shreeve MS, O'Brien CS, Czeisler CA. Prediction of drowsiness events in night shift workers during morning driving. Accid Anal Prev. 2019 May; 126:105-114. PMID: 29126462.
    Citations: 2     Fields:    
  47. Barger LK, Rajaratnam SMW, Cannon CP, Lukas MA, Im K, Goodrich EL, Czeisler CA, O'Donoghue ML. Short Sleep Duration, Obstructive Sleep Apnea, Shiftwork, and the Risk of Adverse Cardiovascular Events in Patients After an Acute Coronary Syndrome. J Am Heart Assoc. 2017 Oct 10; 6(10). PMID: 29018021.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  48. Swanson CM, Shea SA, Wolfe P, Cain SW, Munch M, Vujovic N, Czeisler CA, Buxton OM, Orwoll ES. Bone Turnover Markers After Sleep Restriction and Circadian Disruption: A Mechanism for Sleep-Related Bone Loss in Humans. J Clin Endocrinol Metab. 2017 10 01; 102(10):3722-3730. PMID: 28973223.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  49. Grant LK, Cain SW, Chang AM, Saxena R, Czeisler CA, Anderson C. Impaired cognitive flexibility during sleep deprivation among carriers of the Brain Derived Neurotrophic Factor (BDNF) Val66Met allele. Behav Brain Res. 2018 02 15; 338:51-55. PMID: 28947280.
    Citations:    Fields:    Translation:Humans
  50. McHill AW, Phillips AJ, Czeisler CA, Keating L, Yee K, Barger LK, Garaulet M, Scheer FA, Klerman EB. Later circadian timing of food intake is associated with increased body fat. Am J Clin Nutr. 2017 Nov; 106(5):1213-1219. PMID: 28877894.
    Citations: 14     Fields:    Translation:Humans
  51. Rachmin I, O'Meara CC, Ricci-Blair EM, Feng Y, Christensen EM, Duffy JF, Zitting KM, Czeisler CA, Pancoast JR, Cannon CP, O'Donoghue ML, Morrow DA, Lee RT. Soluble interleukin-13ra1: a circulating regulator of glucose. Am J Physiol Endocrinol Metab. 2017 12 01; 313(6):E663-E671. PMID: 28874358.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  52. Swanson C, Shea SA, Wolfe P, Markwardt S, Cain SW, Munch M, Czeisler CA, Orwoll ES, Buxton OM. 24-hour profile of serum sclerostin and its association with bone biomarkers in men. Osteoporos Int. 2017 Nov; 28(11):3205-3213. PMID: 28744601.
    Citations: 2     Fields:    Translation:HumansCells
  53. Phillips AJK, Clerx WM, O'Brien CS, Sano A, Barger LK, Picard RW, Lockley SW, Klerman EB, Czeisler CA. Irregular sleep/wake patterns are associated with poorer academic performance and delayed circadian and sleep/wake timing. Sci Rep. 2017 06 12; 7(1):3216. PMID: 28607474.
    Citations: 6     Fields:    Translation:Humans
  54. Rahman SA, St Hilaire MA, Chang AM, Santhi N, Duffy JF, Kronauer RE, Czeisler CA, Lockley SW, Klerman EB. Circadian phase resetting by a single short-duration