Harvard Catalyst Profiles

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Warren Myron Zapol, M.D.

Co-Author

This page shows the publications co-authored by Warren Zapol and Fumito Ichinose.
Connection Strength

6.237
  1. Inhaled Pulmonary Vasodilators in Cardiac Surgery Patients: Correct Answer Is "NO". Anesth Analg. 2017 08; 125(2):375-377.
    View in: PubMed
    Score: 0.765
  2. Inhaled nitric oxide: a selective pulmonary vasodilator: current uses and therapeutic potential. Circulation. 2004 Jun 29; 109(25):3106-11.
    View in: PubMed
    Score: 0.309
  3. A selective inducible NOS dimerization inhibitor prevents systemic, cardiac, and pulmonary hemodynamic dysfunction in endotoxemic mice. . 2003 Dec; 285(6):H2524-30.
    View in: PubMed
    Score: 0.290
  4. Cytosolic phospholipase A(2) in hypoxic pulmonary vasoconstriction. J Clin Invest. 2002 Jun; 109(11):1493-500.
    View in: PubMed
    Score: 0.267
  5. Nebulized sildenafil is a selective pulmonary vasodilator in lambs with acute pulmonary hypertension. Crit Care Med. 2001 May; 29(5):1000-5.
    View in: PubMed
    Score: 0.248
  6. Hypoxia ameliorates brain hyperoxia and NAD+ deficiency in a murine model of Leigh syndrome. Mol Genet Metab. 2021 05; 133(1):83-93.
    View in: PubMed
    Score: 0.246
  7. Antimicrobial effects of nitric oxide in murine models of Klebsiella pneumonia. Redox Biol. 2021 02; 39:101826.
    View in: PubMed
    Score: 0.241
  8. Phototherapy and extracorporeal membrane oxygenation facilitate removal of carbon monoxide in rats. Sci Transl Med. 2019 10 09; 11(513).
    View in: PubMed
    Score: 0.223
  9. Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome. . 2019 02 01; 316(2):L391-L399.
    View in: PubMed
    Score: 0.210
  10. Inhaled nitric oxide. Br J Pharmacol. 2019 01; 176(2):246-255.
    View in: PubMed
    Score: 0.209
  11. Pulmonary Delivery of Therapeutic and Diagnostic Gases. J Aerosol Med Pulm Drug Deliv. 2018 04; 31(2):78-87.
    View in: PubMed
    Score: 0.199
  12. Selective pulmonary vasodilation induced by aerosolized zaprinast. Anesthesiology. 1998 Feb; 88(2):410-6.
    View in: PubMed
    Score: 0.198
  13. Sensitivity to Sevoflurane anesthesia is decreased in mice with a congenital deletion of Guanylyl Cyclase-1 alpha. BMC Anesthesiol. 2017 06 14; 17(1):76.
    View in: PubMed
    Score: 0.189
  14. Soluble epoxide hydrolase deficiency or inhibition enhances murine hypoxic pulmonary vasoconstriction after lipopolysaccharide challenge. . 2016 Dec 01; 311(6):L1213-L1221.
    View in: PubMed
    Score: 0.182
  15. Effects of targeted neuronal nitric oxide synthase gene disruption and nitroG-L-arginine methylester on the threshold for isoflurane anesthesia. Anesthesiology. 1995 Jul; 83(1):101-8.
    View in: PubMed
    Score: 0.165
  16. Prolonged pulmonary vasodilator action of inhaled nitric oxide by Zaprinast in awake lambs. J Appl Physiol (1985). 1995 Apr; 78(4):1288-95.
    View in: PubMed
    Score: 0.163
  17. Protective and Detrimental Effects of Sodium Sulfide and Hydrogen Sulfide in Murine Ventilator-induced Lung Injury. Anesthesiology. 2011 Nov; 115(5):1012-21.
    View in: PubMed
    Score: 0.128
  18. Cysteinyl leukotrienes impair hypoxic pulmonary vasoconstriction in endotoxemic mice. Anesthesiology. 2011 Oct; 115(4):804-11.
    View in: PubMed
    Score: 0.128
  19. Administration of hydrogen sulfide via extracorporeal membrane lung ventilation in sheep with partial cardiopulmonary bypass perfusion: a proof of concept study on metabolic and vasomotor effects. Crit Care. 2011; 15(1):R51.
    View in: PubMed
    Score: 0.122
  20. Brief periods of nitric oxide inhalation protect against myocardial ischemia-reperfusion injury. Anesthesiology. 2008 Oct; 109(4):675-82.
    View in: PubMed
    Score: 0.104
  21. Inhaled nitric oxide enables artificial blood transfusion without hypertension. Circulation. 2008 Apr 15; 117(15):1982-90.
    View in: PubMed
    Score: 0.100
  22. Inhaled hydrogen sulfide: a rapidly reversible inhibitor of cardiac and metabolic function in the mouse. Anesthesiology. 2008 Apr; 108(4):659-68.
    View in: PubMed
    Score: 0.100
  23. Congenital NOS2 deficiency prevents impairment of hypoxic pulmonary vasoconstriction in murine ventilator-induced lung injury. . 2007 Nov; 293(5):L1300-5.
    View in: PubMed
    Score: 0.096
  24. Inhaled NO as a therapeutic agent. Cardiovasc Res. 2007 Jul 15; 75(2):339-48.
    View in: PubMed
    Score: 0.094
  25. Inhaled nitric oxide does not reduce systemic vascular resistance in mice. . 2006 May; 290(5):H1826-9.
    View in: PubMed
    Score: 0.085
  26. Inhibition of phosphodiesterase 1 augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs with acute pulmonary hypertension. . 2006 Apr; 290(4):L723-L729.
    View in: PubMed
    Score: 0.085
  27. 5-Lipoxygenase deficiency prevents respiratory failure during ventilator-induced lung injury. Am J Respir Crit Care Med. 2005 Aug 01; 172(3):334-43.
    View in: PubMed
    Score: 0.082
  28. Soluble guanylate cyclase activator reverses acute pulmonary hypertension and augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs. Circulation. 2004 Oct 12; 110(15):2253-9.
    View in: PubMed
    Score: 0.079
  29. Reactive oxygen species scavengers attenuate endotoxin-induced impairment of hypoxic pulmonary vasoconstriction in mice. Anesthesiology. 2002 Nov; 97(5):1227-33.
    View in: PubMed
    Score: 0.069
  30. Radical scavengers protect murine lungs from endotoxin-induced hyporesponsiveness to inhaled nitric oxide. Anesthesiology. 2002 Apr; 96(4):926-33.
    View in: PubMed
    Score: 0.066
  31. Attenuation of hypoxic pulmonary vasoconstriction by endotoxemia requires 5-lipoxygenase in mice. Circ Res. 2001 Apr 27; 88(8):832-8.
    View in: PubMed
    Score: 0.062
  32. Airway stem cells sense hypoxia and differentiate into protective solitary neuroendocrine cells. Science. 2021 01 01; 371(6524):52-57.
    View in: PubMed
    Score: 0.061
  33. High Concentrations of Nitric Oxide Inhalation Therapy in Pregnant Patients With Severe Coronavirus Disease 2019 (COVID-19). Obstet Gynecol. 2020 12; 136(6):1109-1113.
    View in: PubMed
    Score: 0.060
  34. An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance. Nat Biotechnol. 2020 03; 38(3):309-313.
    View in: PubMed
    Score: 0.057
  35. Hypoxic pulmonary blood flow redistribution and arterial oxygenation in endotoxin-challenged NOS2-deficient mice. J Clin Invest. 1999 Nov; 104(10):1421-9.
    View in: PubMed
    Score: 0.056
  36. Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation. Cell Metab. 2019 10 01; 30(4):824-832.e3.
    View in: PubMed
    Score: 0.055
  37. Protocol of a randomised controlled trial in cardiac surgical patients with endothelial dysfunction aimed to prevent postoperative acute kidney injury by administering nitric oxide gas. BMJ Open. 2019 07 04; 9(7):e026848.
    View in: PubMed
    Score: 0.055
  38. Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis. Cell. 2019 05 30; 177(6):1507-1521.e16.
    View in: PubMed
    Score: 0.054
  39. Pulmonary vasodilation by nitric oxide gas and prodrug aerosols in acute pulmonary hypertension. J Appl Physiol (1985). 1998 Feb; 84(2):435-41.
    View in: PubMed
    Score: 0.049
  40. Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene. Circ Res. 1997 Jul; 81(1):34-41.
    View in: PubMed
    Score: 0.048
  41. Pulmonary and Systemic Vascular Resistances After Cardiopulmonary Bypass: Role of Hemolysis. J Cardiothorac Vasc Anesth. 2017 Apr; 31(2):505-515.
    View in: PubMed
    Score: 0.044
  42. Exhaled nitric oxide as a marker for organic nitrate tolerance. Circulation. 1994 Jun; 89(6):2498-502.
    View in: PubMed
    Score: 0.038
  43. Nitric oxide regulates pulmonary vascular smooth muscle cell expression of the inducible cAMP early repressor gene. Nitric Oxide. 2011 Oct 30; 25(3):294-302.
    View in: PubMed
    Score: 0.031
  44. Activation of Toll-like receptor 2 impairs hypoxic pulmonary vasoconstriction in mice. . 2008 Feb; 294(2):L300-8.
    View in: PubMed
    Score: 0.024
  45. In vivo characterization of murine myocardial perfusion with myocardial contrast echocardiography: validation and application in nitric oxide synthase 3 deficient mice. Circulation. 2007 Sep 11; 116(11):1250-7.
    View in: PubMed
    Score: 0.024
  46. Cardiomyocyte-restricted restoration of nitric oxide synthase 3 attenuates left ventricular remodeling after chronic pressure overload. . 2007 Jul; 293(1):H620-7.
    View in: PubMed
    Score: 0.023
  47. Inhaled nitric oxide decreases infarction size and improves left ventricular function in a murine model of myocardial ischemia-reperfusion injury. . 2006 Jul; 291(1):H379-84.
    View in: PubMed
    Score: 0.022
  48. BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia. . 2004 Dec; 287(6):L1241-7.
    View in: PubMed
    Score: 0.019
  49. Congenital deficiency of nitric oxide synthase 2 protects against endotoxin-induced myocardial dysfunction in mice. Circulation. 2000 Sep 19; 102(12):1440-6.
    View in: PubMed
    Score: 0.015
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.