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Edward Paul Weiss, M.D.


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  1. K01DK080886 (WEISS, EDWARD P) Apr 1, 2008 - Mar 31, 2014
    Caloric restriction, exercise, and glucoregulation in humans
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Weiss EP. Mediterranean Diet Improves Running Performance: Reply to Letter From Masten. J Am Coll Nutr. 2020 Aug; 39(6):582-583. PMID: 31985351.
  2. Baker ME, DeCesare KN, Johnson A, Kress KS, Inman CL, Weiss EP. Short-Term Mediterranean Diet Improves Endurance Exercise Performance: A Randomized-Sequence Crossover Trial. J Am Coll Nutr. 2019 Sep-Oct; 38(7):597-605. PMID: 30758261.
  3. Hagberg JM, Coyle EF, Baldwin KM, Cartee GD, Fontana L, Joyner MJ, Kirwan JP, Seals DR, Weiss EP. The historical context and scientific legacy of John O. Holloszy. J Appl Physiol (1985). 2019 08 01; 127(2):277-305. PMID: 30730811.
  4. Jankowski CM, Wolfe P, Schmiege SJ, Nair KS, Khosla S, Jensen M, von Muhlen D, Laughlin GA, Kritz-Silverstein D, Bergstrom J, Bettencourt R, Weiss EP, Villareal DT, Kohrt WM. Sex-specific effects of dehydroepiandrosterone (DHEA) on bone mineral density and body composition: A pooled analysis of four clinical trials. Clin Endocrinol (Oxf). 2019 02; 90(2):293-300. PMID: 30421439.
    Citations:    Fields:    
  5. Wroble KA, Trott MN, Schweitzer GG, Rahman RS, Kelly PV, Weiss EP. Low-carbohydrate, ketogenic diet impairs anaerobic exercise performance in exercise-trained women and men: a randomized-sequence crossover trial. J Sports Med Phys Fitness. 2019 Apr; 59(4):600-607. PMID: 29619799.
    Citations:    Fields:    
  6. Ghoshal S, Stevens JR, Billon C, Girardet C, Sitaula S, Leon AS, Rao DC, Skinner JS, Rankinen T, Bouchard C, Nuñez MV, Stanhope KL, Howatt DA, Daugherty A, Zhang J, Schuelke M, Weiss EP, Coffey AR, Bennett BJ, Sethupathy P, Burris TP, Havel PJ, Butler AA. Adropin: An endocrine link between the biological clock and cholesterol homeostasis. Mol Metab. 2018 02; 8:51-64. PMID: 29331507.
    Citations:    Fields:    Translation:HumansAnimalsCells
  7. Flach A, Jaegers L, Krieger M, Bixler E, Kelly P, Weiss EP, Ahmad SO. Endurance exercise improves function in individuals with Parkinson's disease: A meta-analysis. Neurosci Lett. 2017 10 17; 659:115-119. PMID: 28870627.
    Citations:    Fields:    Translation:Humans
  8. Weiss EP, Jordan RC, Frese EM, Albert SG, Villareal DT. Effects of Weight Loss on Lean Mass, Strength, Bone, and Aerobic Capacity. Med Sci Sports Exerc. 2017 01; 49(1):206-217. PMID: 27580151.
    Citations: 6     Fields:    Translation:Humans
  9. Weinstock J, Farney MR, Elrod NM, Henderson CE, Weiss EP. Exercise as an Adjunctive Treatment for Substance Use Disorders: Rationale and Intervention Description. J Subst Abuse Treat. 2017 01; 72:40-47. PMID: 27666958.
    Citations: 2     Fields:    Translation:Humans
  10. Weiss EP, Reeds DN, Ezekiel UR, Albert SG, Villareal DT. Circulating cytokines as determinants of weight loss-induced improvements in insulin sensitivity. Endocrine. 2017 Jan; 55(1):153-164. PMID: 27605038.
    Citations: 2     Fields:    Translation:Humans
  11. Ueberschlag SL, Seay JR, Roberts AH, DeSpirito PC, Stith JM, Folz RJ, Carter KA, Weiss EP, Zavorsky GS. The Effect of Protandim® Supplementation on Athletic Performance and Oxidative Blood Markers in Runners. PLoS One. 2016; 11(8):e0160559. PMID: 27513339.
    Citations: 1     Fields:    Translation:HumansCells
  12. Stevens JR, Kearney ML, St-Onge MP, Stanhope KL, Havel PJ, Kanaley JA, Thyfault JP, Weiss EP, Butler AA. Inverse association between carbohydrate consumption and plasma adropin concentrations in humans. Obesity (Silver Spring). 2016 08; 24(8):1731-40. PMID: 27460714.
    Citations:    Fields:    Translation:Humans
  13. Weiss EP, Albert SG, Reeds DN, Kress KS, McDaniel JL, Klein S, Villareal DT. Effects of matched weight loss from calorie restriction, exercise, or both on cardiovascular disease risk factors: a randomized intervention trial. Am J Clin Nutr. 2016 Sep; 104(3):576-86. PMID: 27465384.
    Citations: 7     Fields:    Translation:Humans
  14. Corder KE, Newsham KR, McDaniel JL, Ezekiel UR, Weiss EP. Effects of Short-Term Docosahexaenoic Acid Supplementation on Markers of Inflammation after Eccentric Strength Exercise in Women. J Sports Sci Med. 2016 Mar; 15(1):176-83. PMID: 26957941.
    Citations: 3     
  15. Shetty PM, Hauptman PJ, Landfried LK, Patel K, Weiss EP. Micronutrient Deficiencies in Patients With Heart Failure: Relationships With Body Mass Index and Age. J Card Fail. 2015 Dec; 21(12):968-72. PMID: 26456043.
    Citations: 2     Fields:    Translation:Humans
  16. Caciano SL, Inman CL, Gockel-Blessing EE, Weiss EP. Effects of dietary Acid load on exercise metabolism and anaerobic exercise performance. J Sports Sci Med. 2015 Jun; 14(2):364-71. PMID: 25983586.
    Citations: 1     
  17. Weiss EP, Albert SG, Reeds DN, Kress KS, Ezekiel UR, McDaniel JL, Patterson BW, Klein S, Villareal DT. Calorie Restriction and Matched Weight Loss From Exercise: Independent and Additive Effects on Glucoregulation and the Incretin System in Overweight Women and Men. Diabetes Care. 2015 Jul; 38(7):1253-62. PMID: 25877812.
    Citations: 13     Fields:    Translation:Humans
  18. Earhart EL, Weiss EP, Rahman R, Kelly PV. Effects of oral sodium supplementation on indices of thermoregulation in trained, endurance athletes. J Sports Sci Med. 2015 Mar; 14(1):172-8. PMID: 25729305.
  19. Weiss EP. Heart failure risk: effects of red meat, processed red meat, (and enhanced red meat?). Circ Heart Fail. 2014 Jul; 7(4):549-51. PMID: 25028348.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  20. Weiss EP, Royer NK, Fisher JS, Holloszy JO, Fontana L. Postprandial plasma incretin hormones in exercise-trained versus untrained subjects. Med Sci Sports Exerc. 2014 Jun; 46(6):1098-103. PMID: 24576859.
    Citations: 1     Fields:    Translation:Humans
  21. Soare A, Weiss EP, Pozzilli P. Benefits of caloric restriction for cardiometabolic health, including type 2 diabetes mellitus risk. Diabetes Metab Res Rev. 2014 Mar; 30 Suppl 1:41-7. PMID: 24532291.
    Citations: 13     Fields:    Translation:Humans
  22. Soare A, Weiss EP, Holloszy JO, Fontana L. Multiple dietary supplements do not affect metabolic and cardio-vascular health. Aging (Albany NY). 2014 Feb; 6(2):149-57. PMID: 24659610.
    Citations: 8     Fields:    Translation:Humans
  23. Soare A, Weiss EP, Holloszy JO, Fontana L. Multiple dietary supplements do not affect metabolic and cardiovascular health. Aging (Albany NY). 2013 Sep 04. PMID: 24036417.
  24. Kahle LE, Kelly PV, Eliot KA, Weiss EP. Acute sodium bicarbonate loading has negligible effects on resting and exercise blood pressure but causes gastrointestinal distress. Nutr Res. 2013 Jun; 33(6):479-86. PMID: 23746564.
    Citations: 3     Fields:    Translation:Humans
  25. Weiss EP, Villareal DT, Ehsani AA, Fontana L, Holloszy JO. Dehydroepiandrosterone replacement therapy in older adults improves indices of arterial stiffness. Aging Cell. 2012 Oct; 11(5):876-84. PMID: 22712469.
    Citations: 5     Fields:    Translation:Humans
  26. Niekamp K, Zavorsky GS, Fontana L, McDaniel JL, Villareal DT, Weiss EP. Systemic acid load from the diet affects maximal-exercise RER. Med Sci Sports Exerc. 2012 Apr; 44(4):709-15. PMID: 21912302.
    Citations: 2     Fields:    Translation:Humans
  27. Murphy M, Eliot K, Heuertz RM, Weiss E. Whole beetroot consumption acutely improves running performance. J Acad Nutr Diet. 2012 Apr; 112(4):548-52. PMID: 22709704.
    Citations: 21     Fields:    Translation:HumansAnimals
  28. Murphy JC, McDaniel JL, Mora K, Villareal DT, Fontana L, Weiss EP. Preferential reductions in intermuscular and visceral adipose tissue with exercise-induced weight loss compared with calorie restriction. J Appl Physiol (1985). 2012 Jan; 112(1):79-85. PMID: 22016371.
    Citations: 17     Fields:    Translation:Humans
  29. Jouris KB, McDaniel JL, Weiss EP. The Effect of Omega-3 Fatty Acid Supplementation on the Inflammatory Response to eccentric strength exercise. J Sports Sci Med. 2011; 10(3):432-8. PMID: 24150614.
    Citations: 18     
  30. Prior SJ, Jenkins NT, Brandauer J, Weiss EP, Hagberg JM. Aerobic exercise training increases circulating insulin-like growth factor binding protein-1 concentration, but does not attenuate the reduction in circulating insulin-like growth factor binding protein-1 after a high-fat meal. Metabolism. 2012 Mar; 61(3):310-6. PMID: 21872284.
    Citations: 3     Fields:    Translation:Humans
  31. Weiss EP, Fontana L. Caloric restriction: powerful protection for the aging heart and vasculature. . 2011 Oct; 301(4):H1205-19. PMID: 21841020.
    Citations: 55     Fields:    Translation:HumansAnimals
  32. Fox EA, McDaniel JL, Breitbach AP, Weiss EP. Perceived protein needs and measured protein intake in collegiate male athletes: an observational study. J Int Soc Sports Nutr. 2011 Jun 21; 8:9. PMID: 21693050.
    Citations: 2     Fields:    
  33. Weiss EP, Villareal DT, Fontana L, Han DH, Holloszy JO. Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans. Aging (Albany NY). 2011 May; 3(5):533-42. PMID: 21566261.
    Citations: 9     Fields:    Translation:HumansAnimals
  34. Martin CK, Das SK, Lindblad L, Racette SB, McCrory MA, Weiss EP, Delany JP, Kraus WE. Effect of calorie restriction on the free-living physical activity levels of nonobese humans: results of three randomized trials. J Appl Physiol (1985). 2011 Apr; 110(4):956-63. PMID: 21292847.
    Citations: 19     Fields:    Translation:Humans
  35. Aschwald CL, Catanzaro RB, Weiss EP, Gavard JA, Steitz KA, Mostello DJ. Large-for-gestational-age infants of type 1 diabetic mothers: an effect of preprandial hyperglycemia? Gynecol Endocrinol. 2009 Oct; 25(10):653-60. PMID: 19544119.
    Citations: 1     Fields:    Translation:Humans
  36. Weiss EP, Shah K, Fontana L, Lambert CP, Holloszy JO, Villareal DT. Dehydroepiandrosterone replacement therapy in older adults: 1- and 2-y effects on bone. Am J Clin Nutr. 2009 May; 89(5):1459-67. PMID: 19321570.
    Citations: 10     Fields:    Translation:Humans
  37. Dermott M, McDaniel JL, Weiss EP, Tomazic TJ, Mattfeldt-Beman M. Is physical activity associated with appetite? A survey of long-term care residents. J Nutr Elder. 2009 Jan-Mar; 28(1):72-80. PMID: 19234996.
    Citations:    Fields:    Translation:Humans
  38. Weiss EP, Fields DA, Mittendorfer B, Haverkort MA, Klein S. Reproducibility of postprandial lipemia tests and validity of an abbreviated 4-hour test. Metabolism. 2008 Oct; 57(10):1479-85. PMID: 18803956.
    Citations: 14     Fields:    Translation:Humans
  39. Fontana L, Weiss EP, Villareal DT, Klein S, Holloszy JO. Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans. Aging Cell. 2008 10; 7(5):681-7. PMID: 18843793.
    Citations: 97     Fields:    Translation:HumansCTClinical Trials
  40. Hofer T, Fontana L, Anton SD, Weiss EP, Villareal D, Malayappan B, Leeuwenburgh C. Long-term effects of caloric restriction or exercise on DNA and RNA oxidation levels in white blood cells and urine in humans. Rejuvenation Res. 2008 Aug; 11(4):793-9. PMID: 18729811.
    Citations: 25     Fields:    Translation:HumansCells
  41. Wilund KR, Feeney LA, Tomayko EJ, Weiss EP, Hagberg JM. Effects of endurance exercise training on markers of cholesterol absorption and synthesis. Physiol Res. 2009; 58(4):545-52. PMID: 18656998.
    Citations: 9     Fields:    Translation:Humans
  42. Weiss EP, Arif H, Villareal DT, Marzetti E, Holloszy JO. Endothelial function after high-sugar-food ingestion improves with endurance exercise performed on the previous day. Am J Clin Nutr. 2008 Jul; 88(1):51-7. PMID: 18614723.
    Citations: 10     Fields:    Translation:Humans
  43. Racette SB, Weiss EP, Schechtman KB, Steger-May K, Villareal DT, Obert KA, Holloszy JO. Influence of weekend lifestyle patterns on body weight. Obesity (Silver Spring). 2008 Aug; 16(8):1826-30. PMID: 18551108.
    Citations: 24     Fields:    Translation:Humans
  44. Weiss EP, Villareal DT, Racette SB, Steger-May K, Premachandra BN, Klein S, Fontana L. Caloric restriction but not exercise-induced reductions in fat mass decrease plasma triiodothyronine concentrations: a randomized controlled trial. Rejuvenation Res. 2008 Jun; 11(3):605-9. PMID: 18593278.
    Citations: 6     Fields:    Translation:Humans
  45. Riordan MM, Weiss EP, Meyer TE, Ehsani AA, Racette SB, Villareal DT, Fontana L, Holloszy JO, Kovács SJ. The effects of caloric restriction- and exercise-induced weight loss on left ventricular diastolic function. . 2008 Mar; 294(3):H1174-82. PMID: 18162561.
    Citations: 17     Fields:    Translation:Humans
  46. Arif H, Racette SB, Villareal DT, Holloszy JO, Weiss EP. Comparison of methods for assessing abdominal adipose tissue from magnetic resonance images. Obesity (Silver Spring). 2007 Sep; 15(9):2240-4. PMID: 17890492.
    Citations: 4     Fields:    Translation:Humans
  47. Yi Y, Dongmei L, Phares DA, Weiss EP, Brandauer J, Hagberg JM. Association between KCNJ11 E23K genotype and cardiovascular and glucose metabolism phenotypes in older men and women. Exp Physiol. 2008 Jan; 93(1):95-103. PMID: 17720745.
    Citations: 3     Fields:    Translation:Humans
  48. Weiss EP, Holloszy JO. Improvements in body composition, glucose tolerance, and insulin action induced by increasing energy expenditure or decreasing energy intake. J Nutr. 2007 Apr; 137(4):1087-90. PMID: 17374683.
    Citations: 10     Fields:    Translation:Humans
  49. Fontana L, Villareal DT, Weiss EP, Racette SB, Steger-May K, Klein S, Holloszy JO. Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial. Am J Physiol Endocrinol Metab. 2007 Jul; 293(1):E197-202. PMID: 17389710.
    Citations: 66     Fields:    Translation:Humans
  50. Weiss EP, Brandauer J, Kulaputana O, Ghiu IA, Wohn CR, Phares DA, Shuldiner AR, Hagberg JM. FABP2 Ala54Thr genotype is associated with glucoregulatory function and lipid oxidation after a high-fat meal in sedentary nondiabetic men and women. Am J Clin Nutr. 2007 Jan; 85(1):102-8. PMID: 17209184.
    Citations: 9     Fields:    Translation:HumansCells
  51. Villareal DT, Fontana L, Weiss EP, Racette SB, Steger-May K, Schechtman KB, Klein S, Holloszy JO. Bone mineral density response to caloric restriction-induced weight loss or exercise-induced weight loss: a randomized controlled trial. Arch Intern Med. 2006 Dec 11-25; 166(22):2502-10. PMID: 17159017.
    Citations: 74     Fields:    Translation:Humans
  52. Weiss EP, Racette SB, Villareal DT, Fontana L, Steger-May K, Schechtman KB, Klein S, Ehsani AA, Holloszy JO. Lower extremity muscle size and strength and aerobic capacity decrease with caloric restriction but not with exercise-induced weight loss. J Appl Physiol (1985). 2007 Feb; 102(2):634-40. PMID: 17095635.
    Citations: 48     Fields:    Translation:Humans
  53. Weiss EP, Racette SB, Villareal DT, Fontana L, Steger-May K, Schechtman KB, Klein S, Holloszy JO. Improvements in glucose tolerance and insulin action induced by increasing energy expenditure or decreasing energy intake: a randomized controlled trial. Am J Clin Nutr. 2006 Nov; 84(5):1033-42. PMID: 17093155.
    Citations: 111     Fields:    Translation:Humans
  54. Racette SB, Weiss EP, Villareal DT, Arif H, Steger-May K, Schechtman KB, Fontana L, Klein S, Holloszy JO. One year of caloric restriction in humans: feasibility and effects on body composition and abdominal adipose tissue. J Gerontol A Biol Sci Med Sci. 2006 Sep; 61(9):943-50. PMID: 16960025.
    Citations: 64     Fields:    Translation:Humans
  55. Racette SB, Evans EM, Weiss EP, Hagberg JM, Holloszy JO. Abdominal adiposity is a stronger predictor of insulin resistance than fitness among 50-95 year olds. Diabetes Care. 2006 Mar; 29(3):673-8. PMID: 16505525.
    Citations: 27     Fields:    Translation:Humans
  56. Paton CM, Brandauer J, Weiss EP, Brown MD, Ivey FM, Roth SM, Hagberg JM. Hemostatic response to postprandial lipemia before and after exercise training. J Appl Physiol (1985). 2006 Jul; 101(1):316-21. PMID: 16497841.
    Citations: 8     Fields:    Translation:Humans
  57. Weiss EP, Spina RJ, Holloszy JO, Ehsani AA. Gender differences in the decline in aerobic capacity and its physiological determinants during the later decades of life. J Appl Physiol (1985). 2006 Sep; 101(3):938-44. PMID: 16497840.
    Citations: 16     Fields:    Translation:Humans
  58. Racette SB, Weiss EP, Hickner RC, Holloszy JO. Modest weight loss improves insulin action in obese African Americans. Metabolism. 2005 Jul; 54(7):960-5. PMID: 15988708.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  59. Weiss EP, Kulaputana O, Ghiu IA, Brandauer J, Wohn CR, Phares DA, Shuldiner AR, Hagberg JM. Endurance training-induced changes in the insulin response to oral glucose are associated with the peroxisome proliferator-activated receptor-gamma2 Pro12Ala genotype in men but not in women. Metabolism. 2005 Jan; 54(1):97-102. PMID: 15562387.
    Citations: 7     Fields:    Translation:Humans
  60. McKenzie JA, Weiss EP, Ghiu IA, Kulaputana O, Phares DA, Ferrell RE, Hagberg JM. Influence of the interleukin-6 -174 G/C gene polymorphism on exercise training-induced changes in glucose tolerance indexes. J Appl Physiol (1985). 2004 Oct; 97(4):1338-42. PMID: 15180970.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  61. Weiss EP, Park JJ, McKenzie JA, Park JY, Kulaputana O, Brown MD, Phares DA, Hagberg JM. Plasma nitrate/nitrite response to an oral glucose load and the effect of endurance training. Metabolism. 2004 May; 53(5):673-9. PMID: 15131776.
    Citations: 6     Fields:    Translation:Humans
  62. Weiss EP, Brown MD, Shuldiner AR, Hagberg JM. Fatty acid binding protein-2 gene variants and insulin resistance: gene and gene-environment interaction effects. Physiol Genomics. 2002 Sep 03; 10(3):145-57. PMID: 12209017.
    Citations: 23     Fields:    Translation:HumansCells
  63. Hillman CH, Weiss EP, Hagberg JM, Hatfield BD. The relationship of age and cardiovascular fitness to cognitive and motor processes. Psychophysiology. 2002 May; 39(3):303-12. PMID: 12212649.
    Citations: 24     Fields:    Translation:HumansCTClinical Trials
  64. Brown MD, Shuldiner AR, Ferrell RE, Weiss EP, Korytkowski MT, Zmuda JM, McCole SD, Moore GE, Hagberg JM. FABP2 genotype is associated with insulin sensitivity in older women. Metabolism. 2001 Sep; 50(9):1102-5. PMID: 11555846.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  65. Racette SB, Weiss EP, Obert KA, Kohrt WM, Holloszy JO. Modest lifestyle intervention and glucose tolerance in obese African Americans. Obes Res. 2001 Jun; 9(6):348-55. PMID: 11399781.
    Citations: 9     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.