Title Professor of Pediatrics, Emeritus Institution Boston Children's Hospital Address Childrens Hospital Infectious Diseases, Enders 861 300 Longwood Ave Boston MA 02115
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Overview
My laboratory is interested in the pathogenesis of Mycobacterium tuberculosis infection. Our research has focused on the mechanisms by which the bacterium adapts to its environment. Our investigations have centered on analysis of transcription regulation by alternative sigma factors of M. tuberculosis, and characterization of signal transduction in this organism mediated by serine/threonine protein kinases.
Research
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R21AI148988
(HUSSON, ROBERT N)
Jun 8, 2020 - May 31, 2022
Phosphorylation-dependent regulation of protein secretion in Mycobacterium tuberculosis
Role: Principal Investigator
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R21AI146539
(HUSSON, ROBERT N)
Feb 21, 2020 - Jan 31, 2022
Regulation of VapC toxins by Ser/Thr phosphorylation of VapB antitoxins in M. tuberculosis
Role: Principal Investigator
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R21AI130407
(HUSSON, ROBERT N)
Jan 23, 2017 - Dec 31, 2019
Protein labeling with engineered kinases to identify substrates of M. tuberculosis PknA and PknB
Role: Principal Investigator
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R03AI113281
(HUSSON, ROBERT N)
Jul 1, 2014 - Dec 31, 2016
Development of a CRISPR interference system for mycobacteria
Role: Principal Investigator
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R21AI097881
(HUSSON, ROBERT N)
Jul 1, 2012 - Dec 30, 2014
Stress-potentiated screening to identify novel inhibitors of M. tuberculosis
Role: Principal Investigator
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R01AI099204
(HUSSON, ROBERT N)
Apr 16, 2012 - Sep 30, 2018
Chemical Inhibitors to Define an Essential M. Tuberculosis Signaling Network
Role: Principal Investigator
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R21AI082000
(HUSSON, ROBERT N)
May 22, 2009 - Apr 30, 2012
Proteome-wide screen for M. tuberculosis antigens
Role: Principal Investigator
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R03AI066978
(HUSSON, ROBERT N)
Jul 1, 2005 - Jun 30, 2007
An Inducible Expression System for M. tuberculosis
Role: Principal Investigator
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R21AI062275
(HUSSON, ROBERT N)
Jul 1, 2004 - Jun 30, 2007
M tuberculosis PknB: Targeting the Extracellular domain
Role: Principal Investigator
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R01AI059702
(HUSSON, ROBERT N)
Jun 15, 2004 - May 31, 2010
Characterization of M. tuberculosis kinases PknA &PknB
Role: Principal Investigator
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R21AI051707
(HUSSON, ROBERT N)
Jun 1, 2002 - May 31, 2005
Signal Transduction and Latency in M. tuberculosis
Role: Principal Investigator
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R01AI037901
(HUSSON, ROBERT N)
Jun 1, 1995 - Nov 30, 2012
Characterization of Mycobacterial Sigma Factors
Role: Principal Investigator
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K11AI000827
(HUSSON, ROBERT N)
Jul 1, 1987 - Jun 30, 1992
GENES &ANTIGENS OF M TUBERCULOSIS RELATIVE TO IMMUNITY
Role: Principal Investigator
Bibliographic
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