Harvard Catalyst Profiles

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Anthony Peter Weiss, M.D.

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Institution
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Biography
education and training
University of Wisconsin, MadisonBS05/1992Pharmacology and Toxicology
University of Wisconsin, MadisonMD05/1996
Harvard Medical School, BostonMMSc06/2002
Babson College, WellesleyMBA09/2008

Overview
overview
The fundamental framework for both my academic and administrative work is built on my experience as a neuropsychiatrist, and applies a modern cybernetic approach to better understand the complex dynamics of individuals, organizations, and society. Through this frame my work examines questions such as:

1. How can we apply our current neuroscientific understanding of human learning to create optimal learning environments, so that individuals and organizations can grow and flourish?

2. How can we create regulatory and organizational controls on healthcare operations to promote safety, while encouraging professional autonomy and innovation?

3. How can we best understand and mitigate the moral and ethical externalities of dynamic healthcare systems, with a particular focus on the impact on patients with mental health conditions?
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Mentoring
current student opportunities
Available: 06/10/24, Expires: 05/31/26

While significant attention is presently focused on the pace of improvement of artificial intelligence, and its potential application in healthcare, less focus is being placed on the rate of improvement (or lack thereof) in human-provided care. What is the rate of improvement in diagnostic accuracy amongst human physicians as a composite? In technical skill? In empathic listening? In what ways has the deployment of technology diminished our own capacity to provide care, and what are the implications to healthcare as a whole? Focusing on the role of feedback from medical error, this project will examine ways in which technological uptake promotes or diminishes human performance, and considers the medium to long term sequelae of these changes.


Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. K23MH067019 (WEISS, ANTHONY P) Feb 1, 2003 - Jan 31, 2008
    NIH
    Neural Correlates of Source Monitoring in Schizophrenia
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Displaying 25 of 49 total Publications Show all
  1. Weiss AP. Adaptive Machine Learning Systems in Medicine - More Learner, Less Machine. Am J Bioeth. 2024 Oct; 24(10):80-82. PMID: 39283396.
    Citations:
    Fields: EthEthics
  2. O'Donoghue AL, White MH, Weiss AP, Stevens JP, Anderson TS. Trends in Medicare Part B Spending on Discarded Drugs, 2017-2020. JAMA Intern Med. 2023 02 01; 183(2):164-167. PMID: 36534384; PMCID: PMC9857626.
    Citations:
    Fields: IntInternal MedicineTranslation:Humans
  3. Morrell W, Shachar C, Weiss AP. The oversight of autonomous artificial intelligence: lessons from nurse practitioners as physician extenders. J Law Biosci. 2022 Jul-Dec; 9(2):lsac021. PMID: 35968225; PMCID: PMC9366091.
    Citations: 5
  4. Weiss AP. Workplace Violence against Health Care Workers in the United States. N Engl J Med. 2016 08 18; 375(7):e14. PMID: 27532857.
    Citations: 4
    Fields: MedMedicine (General)Translation:Humans
  5. Chang G, Weiss AP, Orav EJ, Rauch SL. Predictors of frequent emergency department use among patients with psychiatric illness. Gen Hosp Psychiatry. 2014 Nov-Dec; 36(6):716-20. PMID: 25312277.
    Citations: 18
    Fields: HosHospitalsPsyPsychiatryTranslation:Humans
  6. Chang TE, Weiss AP, Marques L, Baer L, Vogeli C, Trinh HT, Clain AJ, Blais MA, Fava M, Yeung AS. Race/ethnicity and other social determinants of psychological well-being and functioning in mental health clinics. J Health Care Poor Underserved. 2014 Aug; 25(3):1418-31. PMID: 25130249; PMCID: PMC5672902.
    Citations: 5
    Fields: HeaHealth ServicesTranslation:Humans
  7. Gorrindo T, Goldfarb E, Chevalier L, Hoeppner BB, Birnbaum RJ, Meller B, Alpert JE, Herman J, Weiss AP. Interprofessional differences in disposition decisions: results from a standardized web-based patient assessment. Psychiatr Serv. 2013 Aug 01; 64(8):808-11. PMID: 23903607.
    Citations: 4
    Fields: PsyPsychiatryTranslation:Humans
  8. Weiss AP. Special protections for mental health treatment notes. Virtual Mentor. 2012 Jun 01; 14(6):445-8. PMID: 23351256.
    Citations:
    Fields: EthEthicsTranslation:Humans
  9. Weiss AP, Chang G, Rauch SL, Smallwood JA, Schechter M, Kosowsky J, Hazen E, Haimovici F, Gitlin DF, Finn CT, Orav EJ. Patient- and practice-related determinants of emergency department length of stay for patients with psychiatric illness. Ann Emerg Med. 2012 Aug; 60(2):162-71.e5. PMID: 22555337.
    Citations: 38
    Fields: EmeEmergency MedicineTranslation:Humans
  10. Chang G, Weiss AP, Orav EJ, Smallwood JA, Gonzalez S, Kosowsky JM, Rauch SL. Bottlenecks in the emergency department: the psychiatric clinicians' perspective. Gen Hosp Psychiatry. 2012 Jul-Aug; 34(4):403-9. PMID: 22516215; PMCID: PMC3729212.
    Citations: 11
    Fields: HosHospitalsPsyPsychiatryTranslation:Humans
  11. Huffman JC, Chang TE, Durham LE, Weiss AP. Antipsychotic polytherapy on an inpatient psychiatric unit: how does clinical practice coincide with Joint Commission guidelines? Gen Hosp Psychiatry. 2011 Sep-Oct; 33(5):501-8. PMID: 21762994.
    Citations: 5
    Fields: HosHospitalsPsyPsychiatryTranslation:Humans
  12. Blais MA, Sinclair SJ, Baity MR, Worth J, Weiss AP, Ball LA, Herman J. Measuring outcomes in adult outpatient psychiatry. Clin Psychol Psychother. 2012 May-Jun; 19(3):203-13. PMID: 21416558.
    Citations: 4
    Fields: PsyPsychiatryPsyPsychologyTheTherapeuticsTranslation:Humans
  13. Chang G, Weiss AP, Orav EJ, Jones JA, Finn CT, Gitlin DF, Haimovici F, Hazen E, Kosowsky JM, Schechter MD, Rauch SL. Hospital variability in emergency department length of stay for adult patients receiving psychiatric consultation: a prospective study. Ann Emerg Med. 2011 Aug; 58(2):127-136.e1. PMID: 21227544.
    Citations: 17
    Fields: EmeEmergency MedicineTranslation:Humans
  14. Weiss AP, Ellis CB, Roffman JL, Stufflebeam S, Hamalainen MS, Duff M, Goff DC, Schacter DL. Aberrant frontoparietal function during recognition memory in schizophrenia: a multimodal neuroimaging investigation. J Neurosci. 2009 Sep 09; 29(36):11347-59. PMID: 19741141; PMCID: PMC2768128.
    Citations: 13
    Fields: NeuNeurologyTranslation:Humans
  15. Weiss AP, Guidi J, Fava M. Closing the efficacy-effectiveness gap: translating both the what and the how from randomized controlled trials to clinical practice. J Clin Psychiatry. 2009 Apr; 70(4):446-9. PMID: 19403096.
    Citations: 7
    Fields: PsyPsychiatryTranslation:Humans
  16. Weiss AP. Quality improvement in healthcare: the six ps of root-cause analysis. Am J Psychiatry. 2009 Mar; 166(3):372; author reply 372-3. PMID: 19255055.
    Citations:
    Fields: PsyPsychiatryTranslation:Humans
  17. Roffman JL, Gollub RL, Calhoun VD, Wassink TH, Weiss AP, Ho BC, White T, Clark VP, Fries J, Andreasen NC, Goff DC, Manoach DS. MTHFR 677C --> T genotype disrupts prefrontal function in schizophrenia through an interaction with COMT 158Val --> Met. Proc Natl Acad Sci U S A. 2008 Nov 11; 105(45):17573-8. PMID: 18988738; PMCID: PMC2582272.
    Citations: 53
    Fields: SciScienceTranslation:HumansCells
  18. Roffman JL, Weiss AP, Deckersbach T, Freudenreich O, Henderson DC, Wong DH, Halsted CH, Goff DC. Interactive effects of COMT Val108/158Met and MTHFR C677T on executive function in schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 05; 147B(6):990-5. PMID: 18186041.
    Citations: 34
    Fields: GenGenetics, MedicalNeuNeurologyPsyPsychiatryTranslation:HumansCells
  19. Achim AM, Weiss AP. No evidence for a differential deficit of reality monitoring in schizophrenia: a meta-analysis of the associative memory literature. Cogn Neuropsychiatry. 2008 Sep; 13(5):369-84. PMID: 18781492.
    Citations: 5
    Fields: NeuNeurologyPsyPsychiatryTranslation:Humans
  20. Petersen TJ, Huffman JC, Weiss AP, Blais MA, Andreotti CF, Horwitz MB, Birnbaum RJ. Reach of benchmark psychiatric trial results to community-based providers: a case study of CATIE. J Clin Psychiatry. 2008 Jul; 69(7):1081-6. PMID: 18605813.
    Citations:
    Fields: PsyPsychiatryTranslation:Humans
  21. Jubelt LE, Barr RS, Goff DC, Logvinenko T, Weiss AP, Evins AE. Effects of transdermal nicotine on episodic memory in non-smokers with and without schizophrenia. Psychopharmacology (Berl). 2008 Jul; 199(1):89-98. PMID: 18548234.
    Citations: 54
    Fields: PsyPsychopharmacologyTranslation:Humans
  22. Weiss AP, Duff M, Roffman JL, Rauch SL, Strangman GE. Auditory stimulus repetition effects on cortical hemoglobin oxygenation: a near-infrared spectroscopy investigation. Neuroreport. 2008 Jan 22; 19(2):161-5. PMID: 18185101.
    Citations: 2
    Fields: NeuNeurologyTranslation:Humans
  23. Weiss AP, Goff DC, Duff M, Roffman JL, Schacter DL. Distinguishing familiarity-based from source-based memory performance in patients with schizophrenia. Schizophr Res. 2008 Feb; 99(1-3):208-17. PMID: 17629463; PMCID: PMC2566946.
    Citations: 10
    Fields: PsyPsychiatryTranslation:Humans
  24. Roffman JL, Weiss AP, Purcell S, Caffalette CA, Freudenreich O, Henderson DC, Bottiglieri T, Wong DH, Halsted CH, Goff DC. Contribution of methylenetetrahydrofolate reductase (MTHFR) polymorphisms to negative symptoms in schizophrenia. Biol Psychiatry. 2008 Jan 01; 63(1):42-8. PMID: 17543893.
    Citations: 34
    Fields: PsyPsychiatryPsyPsychophysiologyTranslation:Humans
  25. Barr RS, Culhane MA, Jubelt LE, Mufti RS, Dyer MA, Weiss AP, Deckersbach T, Kelly JF, Freudenreich O, Goff DC, Evins AE. The effects of transdermal nicotine on cognition in nonsmokers with schizophrenia and nonpsychiatric controls. Neuropsychopharmacology. 2008 Feb; 33(3):480-90. PMID: 17443126.
    Citations: 104
    Fields: NeuNeurologyPsyPsychopharmacologyTranslation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.