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Martin Stanley Hirsch, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P30AI042851 (WALKER, BRUCE D) Sep 29, 2000 - Jun 30, 2006
    NIH/NIAID
    PARTNERS/FENWAY/SHATTUCK CENTER FOR AIDS RESEARCH
    Role: Co-Principal Investigator
  2. R01AI049414 (HIRSCH, MARTIN S.) Aug 15, 2000 - Jul 31, 2005
    NIH/NIAID
    COMBINATION ANTI-HIV THERAPY, PATHOGENESIS AND IMMUNITY
    Role: Principal Investigator
  3. R01CA054741 (HIRSCH, MARTIN S.) Mar 8, 1991 - Feb 28, 1995
    NIH/NCI
    HIV/CMV INTERACTIONS
    Role: Principal Investigator
  4. T32AI007387 (KURITZKES, DANIEL R.) Aug 1, 1990 - Jul 31, 2020
    NIH/NIAID
    Multidisciplinary AIDS Training Program
    Role: Co-Principal Investigator
  5. U01AI027659 (KURITZKES, DANIEL R) Jun 30, 1986 - Dec 31, 2006
    NIH/NIAID
    AIDS CLINICAL TRIALS UNIT
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Soumerai JD, Tajmir SH, Hirsch MS, Massoth LR. Case 7-2019: A 73-Year-Old Woman with Swelling of the Right Groin and Fever. N Engl J Med. 2019 Feb 28; 380(9):859-868. PMID: 30811914.
    Citations:    
  2. Hirsch M, Hintz M, Specht A, Schulze-Bonhage A. Tolerability, efficacy and retention rate of Brivaracetam in patients previously treated with Levetiracetam: A monocenter retrospective outcome analysis. Seizure. 2018 Oct; 61:98-103. PMID: 30118932.
    Citations:    Fields:    Translation:Humans
  3. Hirsch M, Begum MR, Paniz É, Barker C, Davis CJ, Duffy J. Diagnosis and management of endometriosis: a systematic review of international and national guidelines. BJOG. 2018 Apr; 125(5):556-564. PMID: 28755422.
    Citations: 1     Fields:    
  4. Hirsch M, Barker C, Duffy JMN. Reply. Am J Obstet Gynecol. 2017 12; 217(6):711. PMID: 28887179.
    Citations:    Fields:    
  5. Hirsch M, Duffy JMN, Deguara CS, Davis CJ, Khan KS. Diagnostic accuracy of Cancer Antigen 125 (CA125) for endometriosis in symptomatic women: A multi-center study. Eur J Obstet Gynecol Reprod Biol. 2017 Mar; 210:102-107. PMID: 27987404.
    Citations: 1     Fields:    Translation:Humans
  6. Hirsch M, Aggarwal S, Barker C, Davis CJ, Duffy JMN. Googling endometriosis: a systematic review of information available on the Internet. Am J Obstet Gynecol. 2017 05; 216(5):451-458.e1. PMID: 27840143.
    Citations: 1     Fields:    Translation:Humans
  7. Heiland DH, Staszewski O, Hirsch M, Masalha W, Franco P, Grauvogel J, Capper D, Schrimpf D, Urbach H, Weyerbrock A. Malignant Transformation of a Dysembryoplastic Neuroepithelial Tumor (DNET) Characterized by Genome-Wide Methylation Analysis. J Neuropathol Exp Neurol. 2016 Apr; 75(4):358-65. PMID: 26921879.
    Citations:    
  8. Frank GM, Adalja A, Barbour A, Casadevall A, Dormitzer PR, Duchin J, Hayden FG, Hirsch MS, Hynes NA, Lipsitch M, Pavia AT, Relman DA. Infectious Diseases Society of America and Gain-of-Function Experiments With Pathogens Having Pandemic Potential. J Infect Dis. 2016 May 01; 213(9):1359-61. PMID: 26416656.
    Citations: 2     Fields:    Translation:HumansAnimalsPHPublic Health
  9. Walensky RP, Hirsch MS. Editorial Commentary: Age-Old Questions: When to Start Antiretroviral Therapy and in Whom? Clin Infect Dis. 2015 Oct 01; 61(7):1196-8. PMID: 26082510.
    Citations:    Fields:    Translation:Humans
  10. Hooper DC, Hirsch MS. Reply to Korch. J Infect Dis. 2014 Nov 01; 210(9):1517-8. PMID: 24808388.
    Citations:    Fields:    Translation:HumansAnimalsCells
  11. Hooper DC, Hirsch MS. Editors' response to johnson. J Infect Dis. 2014 Sep 15; 210(6):993. PMID: 24723475.
    Citations:    
  12. Hooper DC, Hirsch MS. Novel clostridium botulinum toxin and dual use research of concern issues. J Infect Dis. 2014 Jan 15; 209(2):167. PMID: 24106293.
    Citations: 6     Fields:    Translation:HumansCells
  13. Hirsch MS. Hall note. J Infect Dis. 2013 Apr; 207(7):1030. PMID: 23372183.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  14. Walker BD, Hirsch MS. Antiretroviral therapy in early HIV infection. N Engl J Med. 2013 Jan 17; 368(3):279-81. PMID: 23323905.
    Citations: 7     Fields:    Translation:HumansCells
  15. Hirsch MS. Editorial comment regarding H5N1 influenza article in this issue. J Infect Dis. 2013 Jan 15; 207(2):207. PMID: 23042759.
    Citations: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  16. Hirsch MS, Kuritzkes DR. The future of HIV treatment. J Acquir Immune Defic Syndr. 2012 Aug 01; 60 Suppl 2:S39-40. PMID: 22772389.
    Citations: 1     Fields:    Translation:HumansCells
  17. Hirsch MS. Biosecurity and censorship: the H5N1 influenza controversy. J Infect Dis. 2012 Jun; 205(11):1621. PMID: 22454473.
    Citations:    Fields:    Translation:HumansAnimalsCells
  18. Hirsch MS. A new publisher for the Journal of Infectious Diseases. J Infect Dis. 2011 Jan 01; 203(1):1-2. PMID: 21148488.
    Citations:    Fields:    Translation:Humans
  19. Wilkin TJ, Su Z, Krambrink A, Long J, Greaves W, Gross R, Hughes MD, Flexner C, Skolnik PR, Coakley E, Godfrey C, Hirsch M, Kuritzkes DR, Gulick RM. Three-year safety and efficacy of vicriviroc, a CCR5 antagonist, in HIV-1-infected treatment-experienced patients. J Acquir Immune Defic Syndr. 2010 Aug; 54(5):470-6. PMID: 20672447.
    Citations: 12     Fields:    Translation:HumansCellsCTClinical Trials
  20. Thompson MA, Aberg JA, Cahn P, Montaner JS, Rizzardini G, Telenti A, Gatell JM, Günthard HF, Hammer SM, Hirsch MS, Jacobsen DM, Reiss P, Richman DD, Volberding PA, Yeni P, Schooley RT. Antiretroviral treatment of adult HIV infection: 2010 recommendations of the International AIDS Society-USA panel. JAMA. 2010 Jul 21; 304(3):321-33. PMID: 20639566.
    Citations: 287     Fields:    Translation:HumansCells
  21. Tsibris AM, Hirsch MS. Antiretroviral therapy in the clinic. J Virol. 2010 Jun; 84(11):5458-64. PMID: 20181709.
    Citations: 14     Fields:    Translation:Humans
  22. Volberding P, Demeter L, Bosch RJ, Aga E, Pettinelli C, Hirsch M, Vogler M, Martinez A, Little S, Connick E. Antiretroviral therapy in acute and recent HIV infection: a prospective multicenter stratified trial of intentionally interrupted treatment. AIDS. 2009 Sep 24; 23(15):1987-95. PMID: 19696651.
    Citations: 26     Fields:    Translation:HumansCellsCTClinical Trials
  23. Hammer SM, Eron JJ, Reiss P, Schooley RT, Thompson MA, Walmsley S, Cahn P, Fischl MA, Gatell JM, Hirsch MS, Jacobsen DM, Montaner JS, Richman DD, Yeni PG, Volberding PA. Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel. JAMA. 2008 Aug 06; 300(5):555-70. PMID: 18677028.
    Citations: 320     Fields:    Translation:HumansCells
  24. Hirsch MS, Günthard HF, Schapiro JM, Brun-Vézinet F, Clotet B, Hammer SM, Johnson VA, Kuritzkes DR, Mellors JW, Pillay D, Yeni PG, Jacobsen DM, Richman DD. Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel. Top HIV Med. 2008 Aug-Sep; 16(3):266-85. PMID: 19856548.
    Citations: 15     Fields:    
  25. Hirsch MS, DeMaria A, Schaefer PW, Branda JA. Case records of the Massachusetts General Hospital. Case 22-2008. A 52-year-old woman with fever and confusion. N Engl J Med. 2008 Jul 17; 359(3):294-303. PMID: 18635435.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  26. Hirsch MS, Günthard HF, Schapiro JM, Brun-Vézinet F, Clotet B, Hammer SM, Johnson VA, Kuritzkes DR, Mellors JW, Pillay D, Yeni PG, Jacobsen DM, Richman DD. Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel. Clin Infect Dis. 2008 Jul 15; 47(2):266-85. PMID: 18549313.
    Citations: 130     Fields:    Translation:HumansCells
  27. Hirsch MS. Initiating therapy: when to start, what to use. J Infect Dis. 2008 May 15; 197 Suppl 3:S252-60. PMID: 18447611.
    Citations: 5     Fields:    Translation:Humans
  28. Hirsch MS. Global theme issue on poverty and human development. J Infect Dis. 2007 Dec 01; 196(11):1573. PMID: 18008238.
    Citations:    Fields:    Translation:Humans
  29. Hirsch MS. Entecavir surprise. N Engl J Med. 2007 Jun 21; 356(25):2641-3. PMID: 17582076.
    Citations: 3     Fields:    Translation:HumansCells
  30. Gulick RM, Su Z, Flexner C, Hughes MD, Skolnik PR, Wilkin TJ, Gross R, Krambrink A, Coakley E, Greaves WL, Zolopa A, Reichman R, Godfrey C, Hirsch M, Kuritzkes DR. Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-Infected, treatment-experienced patients: AIDS clinical trials group 5211. J Infect Dis. 2007 Jul 15; 196(2):304-12. PMID: 17570119.
    Citations: 83     Fields:    Translation:HumansCellsCTClinical Trials
  31. Hirsch MS. Justice in Libya? Let scientific evidence prevail. J Infect Dis. 2007 Feb 15; 195(4):467-8. PMID: 17315343.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  32. Motsinger AA, Ritchie MD, Shafer RW, Robbins GK, Morse GD, Labbe L, Wilkinson GR, Clifford DB, D'Aquila RT, Johnson VA, Pollard RB, Merigan TC, Hirsch MS, Donahue JP, Kim RB, Haas DW. Multilocus genetic interactions and response to efavirenz-containing regimens: an adult AIDS clinical trials group study. Pharmacogenet Genomics. 2006 Nov; 16(11):837-45. PMID: 17047492.
    Citations: 21     Fields:    Translation:Humans
  33. Hammer SM, Saag MS, Schechter M, Montaner JS, Schooley RT, Jacobsen DM, Thompson MA, Carpenter CC, Fischl MA, Gazzard BG, Gatell JM, Hirsch MS, Katzenstein DA, Richman DD, Vella S, Yeni PG, Volberding PA. Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel. JAMA. 2006 Aug 16; 296(7):827-43. PMID: 16905788.
    Citations: 183     Fields:    Translation:HumansCells
  34. Hammer SM, Saag MS, Schechter M, Montaner JS, Schooley RT, Jacobsen DM, Thompson MA, Carpenter CC, Fischl MA, Gazzard BG, Gatell JM, Hirsch MS, Katzenstein DA, Richman DD, Vella S, Yeni PG, Volberding PA. Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society--USA panel. Top HIV Med. 2006 Aug-Sep; 14(3):827-43. PMID: 17016878.
    Citations: 30     Fields:    
  35. Gandhi RT, Spritzler J, Chan E, Asmuth DM, Rodriguez B, Merigan TC, Hirsch MS, Shafer RW, Robbins GK, Pollard RB. Effect of baseline- and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy in HIV-1-positive subjects: results from ACTG 384. J Acquir Immune Defic Syndr. 2006 Aug 01; 42(4):426-34. PMID: 16810109.
    Citations: 69     Fields:    Translation:Humans
  36. Koenig SP, Kuritzkes DR, Hirsch MS, Léandre F, Mukherjee JS, Farmer PE, del Rio C. Monitoring HIV treatment in developing countries. BMJ. 2006 Mar 11; 332(7541):602-4. PMID: 16528087.
    Citations: 12     Fields:    Translation:Humans
  37. Weinberg A, Tierney C, Kendall MA, Bosch RJ, Patterson-Bartlett J, Erice A, Hirsch MS, Polsky B. Cytomegalovirus-specific immunity and protection against viremia and disease in HIV-infected patients in the era of highly active antiretroviral therapy. J Infect Dis. 2006 Feb 15; 193(4):488-93. PMID: 16425127.
    Citations: 10     Fields:    Translation:HumansCells
  38. Strizki JM, Tremblay C, Xu S, Wojcik L, Wagner N, Gonsiorek W, Hipkin RW, Chou CC, Pugliese-Sivo C, Xiao Y, Tagat JR, Cox K, Priestley T, Sorota S, Huang W, Hirsch M, Reyes GR, Baroudy BM. Discovery and characterization of vicriviroc (SCH 417690), a CCR5 antagonist with potent activity against human immunodeficiency virus type 1. Antimicrob Agents Chemother. 2005 Dec; 49(12):4911-9. PMID: 16304152.
    Citations: 60     Fields:    Translation:HumansCells
  39. Haas DW, Smeaton LM, Shafer RW, Robbins GK, Morse GD, Labbe L, Wilkinson GR, Clifford DB, D'Aquila RT, De Gruttola V, Pollard RB, Merigan TC, Hirsch MS, George AL, Donahue JP, Kim RB. Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study. J Infect Dis. 2005 Dec 01; 192(11):1931-42. PMID: 16267764.
    Citations: 85     Fields:    Translation:Humans
  40. Smith PF, Robbins GK, Shafer RW, Wu H, Yu S, Hirsch MS, Merigan TC, Park JG, Forrest A, Fischl MA, Morse GD. Pharmacokinetics of nelfinavir and efavirenz in antiretroviral-naive, human immunodeficiency virus-infected subjects when administered alone or in combination with nucleoside analog reverse transcriptase inhibitors. Antimicrob Agents Chemother. 2005 Aug; 49(8):3558-61. PMID: 16048984.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  41. Tremblay CL, Giguel F, Guan Y, Chou TC, Takashima K, Hirsch MS. TAK-220, a novel small-molecule CCR5 antagonist, has favorable anti-human immunodeficiency virus interactions with other antiretrovirals in vitro. Antimicrob Agents Chemother. 2005 Aug; 49(8):3483-5. PMID: 16048964.
    Citations: 9     Fields:    Translation:HumansCells
  42. Tremblay CL, Giguel F, Chou TC, Dong H, Takashima K, Hirsch MS. TAK-652, a novel CCR5 inhibitor, has favourable drug interactions with other antiretrovirals in vitro. Antivir Ther. 2005; 10(8):967-8. PMID: 16430202.
    Citations: 5     Fields:    Translation:Cells
  43. Borucki MJ, Spritzler J, Asmuth DM, Gnann J, Hirsch MS, Nokta M, Aweeka F, Nadler PI, Sattler F, Alston B, Nevin TT, Owens S, Waterman K, Hubbard L, Caliendo A, Pollard RB. A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus retinitis. Antiviral Res. 2004 Nov; 64(2):103-11. PMID: 15498605.
    Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
  44. Yeni PG, Hammer SM, Hirsch MS, Saag MS, Schechter M, Carpenter CC, Fischl MA, Gatell JM, Gazzard BG, Jacobsen DM, Katzenstein DA, Montaner JS, Richman DD, Schooley RT, Thompson MA, Vella S, Volberding PA. Treatment for adult HIV infection: 2004 recommendations of the International AIDS Society-USA Panel. JAMA. 2004 Jul 14; 292(2):251-65. PMID: 15249575.
    Citations: 112     Fields:    Translation:Humans
  45. Hirsch MS. Happy birthday to us!! JID reaches 100. J Infect Dis. 2004 Jan 01; 189(1):1-2. PMID: 14702145.
    Citations:    Fields:    
  46. Robbins GK, De Gruttola V, Shafer RW, Smeaton LM, Snyder SW, Pettinelli C, Dubé MP, Fischl MA, Pollard RB, Delapenha R, Gedeon L, van der Horst C, Murphy RL, Becker MI, D'Aquila RT, Vella S, Merigan TC, Hirsch MS. Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection. N Engl J Med. 2003 Dec 11; 349(24):2293-303. PMID: 14668455.
    Citations: 85     Fields:    Translation:HumansCellsCTClinical Trials
  47. Shafer RW, Smeaton LM, Robbins GK, De Gruttola V, Snyder SW, D'Aquila RT, Johnson VA, Morse GD, Nokta MA, Martinez AI, Gripshover BM, Kaul P, Haubrich R, Swingle M, McCarty SD, Vella S, Hirsch MS, Merigan TC. Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. N Engl J Med. 2003 Dec 11; 349(24):2304-15. PMID: 14668456.
    Citations: 55     Fields:    Translation:HumansCellsCTClinical Trials
  48. Gandhi RT, Wurcel A, Rosenberg ES, Johnston MN, Hellmann N, Bates M, Hirsch MS, Walker BD. Progressive reversion of human immunodeficiency virus type 1 resistance mutations in vivo after transmission of a multiply drug-resistant virus. Clin Infect Dis. 2003 Dec 15; 37(12):1693-8. PMID: 14689353.
    Citations: 31     Fields:    Translation:HumansCells
  49. Tremblay CL, Poulin DL, Hicks JL, Selliah S, Chamberland A, Giguel F, Kollmann CS, Chou TC, Dong H, Hirsch MS. Favorable interactions between enfuvirtide and 1-beta-D-2,6-diaminopurine dioxolane in vitro. Antimicrob Agents Chemother. 2003 Nov; 47(11):3644-6. PMID: 14576137.
    Citations: 3     Fields:    Translation:HumansCells
  50. Hirsch MS, Steigbigel RT, Staszewski S, McMahon D, Fischl MA, Hirschel B, Squires K, DiNubile MJ, Harvey CM, Chen J, Leavitt RY. Long-term efficacy, safety, and tolerability of indinavir-based therapy in protease inhibitor-naive adults with advanced HIV infection. Clin Infect Dis. 2003 Oct 15; 37(8):1119-24. PMID: 14523778.
    Citations: 5     Fields:    Translation:HumansCellsCTClinical Trials
  51. Hirsch MS, Brun-Vézinet F, Clotet B, Conway B, Kuritzkes DR, D'Aquila RT, Demeter LM, Hammer SM, Johnson VA, Loveday C, Mellors JW, Richman DD. Questions to and answers from the International AIDS Society-USA Resistance Testing Guidelines Panel. Top HIV Med. 2003 Jul-Aug; 11(4):150-4. PMID: 12876334.
    Citations: 1     Fields:    Translation:HumansCells
  52. Hirsch MS, Brun-Vézinet F, Clotet B, Conway B, Kuritzkes DR, D'Aquila RT, Demeter LM, Hammer SM, Johnson VA, Loveday C, Mellors JW, Jacobsen DM, Richman DD. Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an International AIDS Society-USA Panel. Clin Infect Dis. 2003 Jul 01; 37(1):113-28. PMID: 12830416.
    Citations: 85     Fields:    Translation:HumansCells
  53. Hirsch MS, Werner B. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 17-2003. A 38-year-old woman with fever, headache, and confusion. N Engl J Med. 2003 May 29; 348(22):2239-47. PMID: 12773652.
    Citations:    Fields:    Translation:HumansCells
  54. Tremblay CL, Hicks JL, Sutton L, Giguel F, Flynn T, Johnston M, Sax PE, Walker BD, Hirsch MS, Rosenberg ES, D'Aquila RT. Antiretroviral resistance associated with supervised treatment interruptions in treated acute HIV infection. AIDS. 2003 May 02; 17(7):1086-9. PMID: 12700462.
    Citations: 5     Fields:    Translation:HumansCells
  55. Hirsch MS. HIV drug resistance--a chink in the armor. N Engl J Med. 2002 Aug 08; 347(6):438-9. PMID: 12167687.
    Citations: 1     Fields:    Translation:HumansCells
  56. Yeni PG, Hammer SM, Carpenter CC, Cooper DA, Fischl MA, Gatell JM, Gazzard BG, Hirsch MS, Jacobsen DM, Katzenstein DA, Montaner JS, Richman DD, Saag MS, Schechter M, Schooley RT, Thompson MA, Vella S, Volberding PA. Antiretroviral treatment for adult HIV infection in 2002: updated recommendations of the International AIDS Society-USA Panel. JAMA. 2002 Jul 10; 288(2):222-35. PMID: 12095387.
    Citations: 126     Fields:    Translation:Humans
  57. Tremblay CL, Giguel F, Kollmann C, Guan Y, Chou TC, Baroudy BM, Hirsch MS. Anti-human immunodeficiency virus interactions of SCH-C (SCH 351125), a CCR5 antagonist, with other antiretroviral agents in vitro. Antimicrob Agents Chemother. 2002 May; 46(5):1336-9. PMID: 11959565.
    Citations: 26     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.