Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Warren Gary Hill, Ph.D.

Profile Picture

University of Otago, New ZealandM.Sc.1985Biochemistry
University of Adelaide, AustraliaPhD1996Cell Biology
University of Pittsburgh, PennsylvaniaPost-Doc1999Physiology/Biophysics
2014 - 2019
Associate Editor, Am. J. Physiol. Renal Physiol.
2014 - 2019
Editorial Board, Bladder
2018 - 2019
Editorial Board, Scientific Reports


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK083299 (HILL, WARREN G.) Mar 15, 2010 - Feb 28, 2016
    Role of Integrins in Bladder Urothelium
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. de Oliveira MG, Monica FZ, Passos GR, Victorio JA, Davel AP, Oliveira ALL, Parada CA, D'Ancona CAL, Hill WG, Antunes E. Selective Pharmacological Inhibition of NOX2 by GSK2795039 Improves Bladder Dysfunction in Cyclophosphamide-Induced Cystitis in Mice. Antioxidants (Basel). 2022 Dec 30; 12(1). PMID: 36670953; PMCID: PMC9854480.
  2. Zhu K, Hill WG, Li F, Shi B, Chai TC. Urine and Tissue Bacterial Loads Correlate With Voiding Behaviors in a Murine Urinary Tract Infection Model. Urology. 2021 08; 154:344.e1-344.e7. PMID: 34010680.
    Citations:    Fields:    Translation:Animals
  3. Xie X, Chen H, Zhang L, Chan D, Hill WG, Zeidel ML, Yu W. Molecular mechanisms of voiding dysfunction in a novel mouse model of acute urinary retention. FASEB J. 2021 04; 35(4):e21447. PMID: 33742688; PMCID: PMC9844132.
    Citations:    Fields:    Translation:Animals
  4. Zhu K, Hill WG, Li F, Shi B, Chai TC. Early Increased Urinary IL-2 and IL-10 Levels Were Associated With Development of Chronic UTI in a Murine Model. Urology. 2020 07; 141:188.e1-188.e6. PMID: 32201154.
    Citations: 2     Fields:    Translation:Animals
  5. Kim AK, Hamadani C, Zeidel ML, Hill WG. Urological complications of obesity and diabetes in males and females of three mouse models: temporal manifestations. Am J Physiol Renal Physiol. 2020 01 01; 318(1):F160-F174. PMID: 31682171.
    Citations: 3     Fields:    Translation:Animals
  6. Hao Y, Wang L, Chen H, Hill WG, Robson SC, Zeidel ML, Yu W. Targetable purinergic receptors P2Y12 and A2b antagonistically regulate bladder function. JCI Insight. 2019 08 22; 4(16). PMID: 31434806.
    Citations: 4     Fields:    Translation:AnimalsCells
  7. Hill WG, Zeidel ML, Bjorling DE, Vezina CM. Void spot assay: recommendations on the use of a simple micturition assay for mice. Am J Physiol Renal Physiol. 2018 11 01; 315(5):F1422-F1429. PMID: 30156116; PMCID: PMC6293303.
    Citations: 22     Fields:    Translation:Animals
  8. Wegner KA, Abler LL, Oakes SR, Mehta GS, Ritter KE, Hill WG, Zwaans BM, Lamb LE, Wang Z, Bjorling DE, Ricke WA, Macoska J, Marker PC, Southard-Smith EM, Eliceiri KW, Vezina CM. Void spot assay procedural optimization and software for rapid and objective quantification of rodent voiding function, including overlapping urine spots. Am J Physiol Renal Physiol. 2018 10 01; 315(4):F1067-F1080. PMID: 29972322; PMCID: PMC6230749.
    Citations: 21     Fields:    Translation:Animals
  9. Acevedo-Alvarez M, Yeh J, Alvarez-Lugo L, Lu M, Sukumar N, Hill WG, Chai TC. Mouse urothelial genes associated with voiding behavior changes after ovariectomy and bladder lipopolysaccharide exposure. Neurourol Urodyn. 2018 11; 37(8):2398-2405. PMID: 29682797.
    Citations: 3     Fields:    Translation:Animals
  10. Yu W, Hill WG, Robson SC, Zeidel ML. Role of P2X4 Receptor in Mouse Voiding Function. Sci Rep. 2018 01 30; 8(1):1838. PMID: 29382907.
    Citations: 7     Fields:    Translation:AnimalsCells
  11. Chen H, Zhang L, Hill WG, Yu W. Evaluating the voiding spot assay in mice: a simple method with complex environmental interactions. Am J Physiol Renal Physiol. 2017 Dec 01; 313(6):F1274-F1280. PMID: 28835420; PMCID: PMC5814640.
    Citations: 12     Fields:    Translation:Animals
  12. Hill WG, Yu W. Special K: once the fun is over an EMT arrives for the bladder. Am J Physiol Renal Physiol. 2017 12 01; 313(6):F1179-F1180. PMID: 28539335; PMCID: PMC6148339.
    Citations:    Fields:    
  13. Kim AK, Hill WG. Effect of filling rate on cystometric parameters in young and middle aged mice. Bladder (San Franc). 2017; 4(1). PMID: 28553656; PMCID: PMC5443651.
    Citations: 3     
  14. Guo C, Balsara ZR, Hill WG, Li X. Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration. Development. 2017 02 01; 144(3):400-408. PMID: 28049658.
    Citations: 8     Fields:    Translation:AnimalsCells
  15. Ackert-Bicknell CL, Anderson LC, Sheehan S, Hill WG, Chang B, Churchill GA, Chesler EJ, Korstanje R, Peters LL. Aging Research Using Mouse Models. Curr Protoc Mouse Biol. 2015 Jun 01; 5(2):95-133. PMID: 26069080.
    Citations: 37     Fields:    Translation:HumansAnimals
  16. Bjorling DE, Wang Z, Vezina CM, Ricke WA, Keil KP, Yu W, Guo L, Zeidel ML, Hill WG. Evaluation of voiding assays in mice: impact of genetic strains and sex. Am J Physiol Renal Physiol. 2015 Jun 15; 308(12):F1369-78. PMID: 25904700; PMCID: PMC4469884.
    Citations: 37     Fields:    Translation:Animals
  17. Hill WG. New impetus for innovation in benign urology. Am J Physiol Renal Physiol. 2015 Apr 15; 308(8):F797-8. PMID: 25673806.
    Citations:    Fields:    Translation:HumansAnimals
  18. Yu W, Sun X, Robson SC, Hill WG. ADP-induced bladder contractility is mediated by P2Y12 receptor and temporally regulated by ectonucleotidases and adenosine signaling. FASEB J. 2014 Dec; 28(12):5288-98. PMID: 25208846.
    Citations: 9     Fields:    Translation:AnimalsCells
  19. Hill WG. Control of urinary drainage and voiding. Clin J Am Soc Nephrol. 2015 Mar 06; 10(3):480-92. PMID: 24742475.
    Citations: 19     Fields:    Translation:HumansCells
  20. Yu W, Ackert-Bicknell C, Larigakis JD, MacIver B, Steers WD, Churchill GA, Hill WG, Zeidel ML. Spontaneous voiding by mice reveals strain-specific lower urinary tract function to be a quantitative genetic trait. Am J Physiol Renal Physiol. 2014 Jun 01; 306(11):F1296-307. PMID: 24717733.
    Citations: 50     Fields:    Translation:Animals
  21. Yu W, Hill WG. Lack of specificity shown by P2Y6 receptor antibodies. Naunyn Schmiedebergs Arch Pharmacol. 2013 Oct; 386(10):885-91. PMID: 23793102.
    Citations: 17     Fields:    Translation:Animals
  22. Kanasaki K, Yu W, von Bodungen M, Larigakis JD, Kanasaki M, Ayala de la Pena F, Kalluri R, Hill WG. Loss of ß1-integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype. FASEB J. 2013 May; 27(5):1950-61. PMID: 23395910.
    Citations: 24     Fields:    Translation:AnimalsCells
  23. Yu W, Sun X, Robson SC, Hill WG. Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y(6) activation of the phospholipase C/inositol trisphosphate pathway. FASEB J. 2013 May; 27(5):1895-903. PMID: 23362118.
    Citations: 17     Fields:    Translation:AnimalsCells
  24. Yu W, Zeidel ML, Hill WG. Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast. PLoS One. 2012; 7(11):e48897. PMID: 23145014.
    Citations: 26     Fields:    Translation:AnimalsCells
  25. Zocher F, Zeidel ML, Missner A, Sun TT, Zhou G, Liao Y, von Bodungen M, Hill WG, Meyers S, Pohl P, Mathai JC. Uroplakins do not restrict CO2 transport through urothelium. J Biol Chem. 2012 Mar 30; 287(14):11011-7. PMID: 22315218; PMCID: PMC3322830.
    Citations: 10     Fields:    Translation:AnimalsCells
  26. Yu W, Hill WG. Defining protein expression in the urothelium: a problem of more than transitional interest. Am J Physiol Renal Physiol. 2011 Nov; 301(5):F932-42. PMID: 21880838.
    Citations: 18     Fields:    Translation:HumansAnimals
  27. Yu W, Robson SC, Hill WG. Expression and distribution of ectonucleotidases in mouse urinary bladder. PLoS One. 2011 Apr 14; 6(4):e18704. PMID: 21533188.
    Citations: 29     Fields:    Translation:AnimalsCells
  28. Yu W, Hill WG, Apodaca G, Zeidel ML. Expression and distribution of transient receptor potential (TRP) channels in bladder epithelium. Am J Physiol Renal Physiol. 2011 Jan; 300(1):F49-59. PMID: 20943764.
    Citations: 53     Fields:    Translation:Animals
  29. MacIver B, Cutler CP, Yin J, Hill MG, Zeidel ML, Hill WG. Expression and functional characterization of four aquaporin water channels from the European eel (Anguilla anguilla). J Exp Biol. 2009 Sep 01; 212(17):2856-63. PMID: 19684221.
    Citations: 18     Fields:    Translation:Animals
  30. Hill WG, Meyers S, von Bodungen M, Apodaca G, Dedman JR, Kaetzel MA, Zeidel ML. Studies on localization and function of annexin A4a within urinary bladder epithelium using a mouse knockout model. Am J Physiol Renal Physiol. 2008 Apr; 294(4):F919-27. PMID: 18256316.
    Citations: 7     Fields:    Translation:Animals
  31. Maciver B, Smith CP, Hill WG, Zeidel ML. Functional characterization of mouse urea transporters UT-A2 and UT-A3 expressed in purified Xenopus laevis oocyte plasma membranes. Am J Physiol Renal Physiol. 2008 Apr; 294(4):F956-64. PMID: 18256317.
    Citations: 16     Fields:    Translation:AnimalsCells
  32. Hill WG, Butterworth MB, Wang H, Edinger RS, Lebowitz J, Peters KW, Frizzell RA, Johnson JP. The epithelial sodium channel (ENaC) traffics to apical membrane in lipid rafts in mouse cortical collecting duct cells. J Biol Chem. 2007 Dec 28; 282(52):37402-11. PMID: 17932048.
    Citations: 32     Fields:    Translation:AnimalsCells
  33. Carattino MD, Liu W, Hill WG, Satlin LM, Kleyman TR. Lack of a role of membrane-protein interactions in flow-dependent activation of ENaC. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F316-24. PMID: 17459954.
    Citations: 15     Fields:    Translation:AnimalsCells
  34. Gensure RH, Zeidel ML, Hill WG. Lipid raft components cholesterol and sphingomyelin increase H+/OH- permeability of phosphatidylcholine membranes. Biochem J. 2006 Sep 15; 398(3):485-95. PMID: 16706750; PMCID: PMC1559473.
    Citations: 13     Fields:    Translation:Cells
  35. Kaufmann N, Mathai JC, Hill WG, Dow JA, Zeidel ML, Brodsky JL. Developmental expression and biophysical characterization of a Drosophila melanogaster aquaporin. Am J Physiol Cell Physiol. 2005 Aug; 289(2):C397-407. PMID: 15800049.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  36. Hill WG, Southern NM, MacIver B, Potter E, Apodaca G, Smith CP, Zeidel ML. Isolation and characterization of the Xenopus oocyte plasma membrane: a new method for studying activity of water and solute transporters. Am J Physiol Renal Physiol. 2005 Jul; 289(1):F217-24. PMID: 15741609.
    Citations: 28     Fields:    Translation:AnimalsCells
  37. Hill WG, Almasri E, Ruiz WG, Apodaca G, Zeidel ML. Water and solute permeability of rat lung caveolae: high permeabilities explained by acyl chain unsaturation. Am J Physiol Cell Physiol. 2005 Jul; 289(1):C33-41. PMID: 15728712.
    Citations: 6     Fields:    Translation:AnimalsCells
  38. Awayda MS, Shao W, Guo F, Zeidel M, Hill WG. ENaC-membrane interactions: regulation of channel activity by membrane order. J Gen Physiol. 2004 Jun; 123(6):709-27. PMID: 15148329; PMCID: PMC2234566.
    Citations: 14     Fields:    Translation:AnimalsCells
  39. Hill WG, Mathai JC, Gensure RH, Zeidel JD, Apodaca G, Saenz JP, Kinne-Saffran E, Kinne R, Zeidel ML. Permeabilities of teleost and elasmobranch gill apical membranes: evidence that lipid bilayers alone do not account for barrier function. Am J Physiol Cell Physiol. 2004 Jul; 287(1):C235-42. PMID: 14998788.
    Citations: 2     Fields:    Translation:AnimalsCells
  40. Hill WG, Zeidel ML. Editorial: Membrane protein interactions in the bladder--charges of disorderly conduct. J Urol. 2003 Nov; 170(5):2095-6. PMID: 14532861.
    Citations: 2     Fields:    Translation:Animals
  41. Carattino MD, Hill WG, Kleyman TR. Arachidonic acid regulates surface expression of epithelial sodium channels. J Biol Chem. 2003 Sep 19; 278(38):36202-13. PMID: 12837767.
    Citations: 30     Fields:    Translation:AnimalsCells
  42. Hill WG, Kaetzel MA, Kishore BK, Dedman JR, Zeidel ML. Annexin A4 reduces water and proton permeability of model membranes but does not alter aquaporin 2-mediated water transport in isolated endosomes. J Gen Physiol. 2003 May; 121(5):413-25. PMID: 12695484; PMCID: PMC2217383.
    Citations: 15     Fields:    Translation:AnimalsCells
  43. Hill WG, An B, Johnson JP. Endogenously expressed epithelial sodium channel is present in lipid rafts in A6 cells. J Biol Chem. 2002 Sep 13; 277(37):33541-4. PMID: 12167633.
    Citations: 35     Fields:    Translation:Cells
  44. Krylov AV, Pohl P, Zeidel ML, Hill WG. Water permeability of asymmetric planar lipid bilayers: leaflets of different composition offer independent and additive resistances to permeation. J Gen Physiol. 2001 Oct; 118(4):333-40. PMID: 11585847; PMCID: PMC2233699.
    Citations: 32     Fields:    Translation:Animals
  45. Gibson GA, Hill WG, Weisz OA. Evidence against the acidification hypothesis in cystic fibrosis. Am J Physiol Cell Physiol. 2000 Oct; 279(4):C1088-99. PMID: 11003589.
    Citations: 8     Fields:    Translation:AnimalsCells
  46. Hill WG, Zeidel ML. Reconstituting the barrier properties of a water-tight epithelial membrane by design of leaflet-specific liposomes. J Biol Chem. 2000 Sep 29; 275(39):30176-85. PMID: 10903312.
    Citations: 35     Fields:    Translation:AnimalsCells
  47. Howard M, Jiang X, Stolz DB, Hill WG, Johnson JA, Watkins SC, Frizzell RA, Bruton CM, Robbins PD, Weisz OA. Forskolin-induced apical membrane insertion of virally expressed, epitope-tagged CFTR in polarized MDCK cells. Am J Physiol Cell Physiol. 2000 Aug; 279(2):C375-82. PMID: 10913004.
    Citations: 26     Fields:    Translation:AnimalsCells
  48. Bünger L, Hill WG. Role of growth hormone in the genetic change of mice divergently selected for body weight and fatness. Genet Res. 1999 Dec; 74(3):351-60. PMID: 10689811.
    Citations: 1     Fields:    Translation:Animals
  49. Hill WG, Rivers RL, Zeidel ML. Role of leaflet asymmetry in the permeability of model biological membranes to protons, solutes, and gases. J Gen Physiol. 1999 Sep; 114(3):405-14. PMID: 10469730; PMCID: PMC2229456.
    Citations: 17     Fields:    
  50. Hill WG, Harper GS, Rozaklis T, Hopwood JJ. Enhanced channelling of sulphate through a rapidly exchangeable sulphate pool in response to stimulated glycosaminoglycan synthesis in pancreatic epithelial cells. Biochim Biophys Acta. 1999 Jul 07; 1454(2):174-82. PMID: 10381562.
    Citations: 1     Fields:    Translation:HumansCells
  51. Bünger L, Wallace H, Bishop JO, Hastings IM, Hill WG. Effects of thyroid hormone deficiency on mice selected for increased and decreased body weight and fatness. Genet Res. 1998 Aug; 72(1):39-53. PMID: 9802260.
    Citations:    Fields:    Translation:Animals
  52. Jiang X, Hill WG, Pilewski JM, Weisz OA. Glycosylation differences between a cystic fibrosis and rescued airway cell line are not CFTR dependent. Am J Physiol. 1997 11; 273(5):L913-20. PMID: 9374717.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  53. Hill WG, Harper GS, Rozaklis T, Boucher RC, Hopwood JJ. Organ-specific over-sulfation of glycosaminoglycans and altered extracellular matrix in a mouse model of cystic fibrosis. Biochem Mol Med. 1997 Oct; 62(1):113-22. PMID: 9367807.
    Citations: 1     Fields:    Translation:AnimalsCells
  54. Hill WG, Harper GS, Rozaklis T, Hopwood JJ. Sulfation of chondroitin/dermatan sulfate by cystic fibrosis pancreatic duct cells is not different from control cells. Biochem Mol Med. 1997 Oct; 62(1):85-94. PMID: 9367803.
    Citations: 1     Fields:    Translation:HumansCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Hill's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (301)
Co-Authors (6)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.