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Helen A. Christou, M.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R21EY024114 (INDER, TERRIE E) Jan 1, 2015 - Jun 30, 2015
    NIH
    The Pathomechanistic Role of Endothelial IDO in proliferative Retinopathy
    Role: Principal Investigator
  2. R01HL116573 (CHRISTOU, HELEN) Sep 1, 2014 - Jul 31, 2019
    NIH
    Vascular smooth muscle cell phenotypic switching in Pulmonary Hypertension
    Role: Principal Investigator
  3. K08HL003917 (CHRISTOU, HELEN) Jan 15, 2000 - Dec 31, 2005
    NIH
    THE ROLE OF CARBON MONOXIDE IN VASCULAR HOMEOSTASIS
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Babacheva E, Rallis D, Christou H, Mitsiakos G, Mikos T, Dampala K, Tsakalidis C, Kioumi A, Goulis DG, Soubasi V. Maternal diabetes and the role of neonatal reticulocyte hemoglobin content as a biomarker of iron status in the perinatal period. Front Endocrinol (Lausanne). 2022; 13:1011897. PMID: 36425471; PMCID: PMC9679283.
    Citations:    Fields:    Translation:HumansCells
  2. Kosmas K, Michael Z, Papathanasiou AE, Spyropoulos F, Adib E, Jasuja R, Christou H. Skeletal Muscle Dysfunction in Experimental Pulmonary Hypertension. Int J Mol Sci. 2022 Sep 18; 23(18). PMID: 36142826; PMCID: PMC9501428.
    Citations:    Fields:    Translation:AnimalsCells
  3. Gray MM, Bruno C, French H, Myers P, Carbajal MM, Reber KM, Christou H, Karpen H, Johnston LC. Changes, Challenges, and Variations in Neonatal-Perinatal Medicine Fellowship: A View from the Program Directors. Am J Perinatol. 2022 Jun 23. PMID: 35554889.
    Citations:    Fields:    
  4. Christou H. Pleiotropic Effects of Pyruvate Kinase M2 in Right Ventricular Failure and Pulmonary Arterial Hypertension. JACC Basic Transl Sci. 2022 Apr; 7(4):404-405. PMID: 35540102; PMCID: PMC9079847.
    Citations:    
  5. Christou H, Khalil RA. Mechanisms of pulmonary vascular dysfunction in pulmonary hypertension and implications for novel therapies. Am J Physiol Heart Circ Physiol. 2022 05 01; 322(5):H702-H724. PMID: 35213243; PMCID: PMC8977136.
    Citations: 5     Fields:    Translation:HumansCells
  6. Shrestha S, Lamattina A, Pacheco-Rodriguez G, Ng J, Liu X, Sonawane A, Imani J, Qiu W, Kosmas K, Louis P, Hentschel A, Steagall WK, Onishi R, Christou H, Henske EP, Glass K, Perrella MA, Moss J, Tantisira K, El-Chemaly S. ETV2 regulates PARP-1 binding protein to induce ER stress-mediated death in tuberin-deficient cells. Life Sci Alliance. 2022 05; 5(5). PMID: 35181635; PMCID: PMC8860090.
    Citations:    Fields:    Translation:Humans
  7. Spyropoulos F, Sorrentino A, van der Reest J, Yang P, Waldeck-Weiermair M, Steinhorn B, Eroglu E, Saeedi Saravi SS, Yu P, Haigis M, Christou H, Michel T. Metabolomic and transcriptomic signatures of chemogenetic heart failure. Am J Physiol Heart Circ Physiol. 2022 03 01; 322(3):H451-H465. PMID: 35089810; PMCID: PMC8896991.
    Citations: 3     Fields:    Translation:AnimalsCells
  8. Abend N, Adams E, Al Balushi A, Alburaki W, Appendino J, Barbosa VS, Birca A, Bonifacio S, Branagan A, Chang T, Chowdhury R, Christou H, Chu C, Cilio MR, Comani S, Corsi-Cabrera M, Croce P, Cubero-Rego L, Dawoud F, de Vries L, Dehaes M, Devane D, Duncan A, El Ters N, El-Dib M, Elshibiny H, Esser M, Fairchild K, Finucane E, Franceschini MA, Gallagher A, Ghosh A, Glass H, Venkata SKRG, Baillet TH, Herzberg E, Hildrey E, Hurley T, Inder T, Jacobs E, Jefferies K, Jermendy A, Khazaei M, Kilmartin K, King G, Lauronen L, Lee S, Leijser L, Lind J, Llaguno NS, Machie M, Magalhães M, Mahdi Z, Maluomi J, Marandyuk B, Massey S, McCulloch C, Metsäranta M, Mikkonen K, Mohammad K, Molloy E, Momin S, Munster C, Murthy P, Netto A, Nevalainen P, Nguyen J, Nieves M, Nyman J, Oliver N, Peeters C, Pietrobom RFR, Pijpers J, Pinchefksy E, Ping YB, Quirke F, Raeisi K, Ricardo-Garcell J, Robinson J, Rodrigues DP, Rosati J, Scott J, Scringer-Wilkes M, Shellhaas R, Smit L, Soul J, Srivastava A, Steggerda S, Sunwoo J, Szakmar E, Tamburro G, Thomas S, Toiviainen-Salo S, Toma AI, Vanhatalo S, Variane GFT, Vein A, Vesoulis Z, Vilan A, Volpe J, Weeke L, Wintermark P, Wusthoff C, Zappasodi F, Zein H, Zempel J. Proceedings of the 13th International Newborn Brain Conference: Neonatal Neurocritical Care, Seizures, and Continuous EEG monitoring. J Neonatal Perinatal Med. 2022; 15(2):467-485. PMID: 35431189.
    Citations:    Fields:    Translation:Humans
  9. Spyropoulos F, Michael Z, Finander B, Vitali S, Kosmas K, Zymaris P, Kalish BT, Kourembanas S, Christou H. Acetazolamide Improves Right Ventricular Function and Metabolic Gene Dysregulation in Experimental Pulmonary Arterial Hypertension. Front Cardiovasc Med. 2021; 8:662870. PMID: 34222363.
    Citations: 1     
  10. Hansmann G, Christou H, Koestenberger M, Sallmon H. Off-label use of PAH-targeted medications approved for adults and their financial coverage by health insurances are vital for children with pulmonary hypertension. Eur J Clin Invest. 2021 Aug; 51(8):e13571. PMID: 33834481.
    Citations: 1     Fields:    Translation:Humans
  11. Christou H, Michael Z, Spyropoulos F, Chen Y, Rong D, Khalil RA. Carbonic anhydrase inhibition improves pulmonary artery reactivity and nitric oxide-mediated relaxation in sugen-hypoxia model of pulmonary hypertension. Am J Physiol Regul Integr Comp Physiol. 2021 06 01; 320(6):R835-R850. PMID: 33826428; PMCID: PMC8285620.
    Citations: 2     Fields:    Translation:Animals
  12. Papathanasiou AE, Spyropoulos F, Michael Z, Joung KE, Briana DD, Malamitsi-Puchner A, Mantzoros CS, Christou H. Adipokines and Metabolic Regulators in Human and Experimental Pulmonary Arterial Hypertension. Int J Mol Sci. 2021 Feb 01; 22(3). PMID: 33535425; PMCID: PMC7867052.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  13. Niccum M, Spyropoulos F, Levin JC, Petty CR, Mullen MP, Christou H. Lower oxygen saturation targets in preterm infants are not associated with increased rates of pulmonary hypertension. J Neonatal Perinatal Med. 2021; 14(4):519-526. PMID: 33720854.
    Citations:    Fields:    Translation:Humans
  14. Spyropoulos F, Vitali SH, Touma M, Rose CD, Petty CR, Levy P, Kourembanas S, Christou H. Echocardiographic markers of pulmonary hemodynamics and right ventricular hypertrophy in rat models of pulmonary hypertension. Pulm Circ. 2020 Apr-Jun; 10(2):2045894020910976. PMID: 32537128; PMCID: PMC7268140.
    Citations: 4     
  15. Joung KE, Clausen D, Herdt A, Presti A, Snyder R, Peters C, Christou H, Mantzoros CS. Association of circulating FGF-21 levels in the first week of life and postnatal growth in hospitalized preterm infants. Metabol Open. 2020 Mar; 5:100030. PMID: 32812922; PMCID: PMC7424778.
    Citations: 1     
  16. Basak A, Munschauer M, Lareau CA, Montbleau KE, Ulirsch JC, Hartigan CR, Schenone M, Lian J, Wang Y, Huang Y, Wu X, Gehrke L, Rice CM, An X, Christou HA, Mohandas N, Carr SA, Chen JJ, Orkin SH, Lander ES, Sankaran VG. Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation. Nat Genet. 2020 02; 52(2):138-145. PMID: 31959994; PMCID: PMC7031047.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  17. DiPrisco B, Kumar A, Kalra B, Savjani GV, Michael Z, Farr O, Papathanasiou AE, Christou H, Mantzoros CS. GLYCOSYLATED FIBRONECTIN AND INHIBIN ARE LOWER AND ANTI-MÜLLERIAN HORMONE IS HIGHER IN UMBILICAL CORD BLOOD WHEN MOTHERS HAVE PREECLAMPSIA. Endocr Pract. 2020 Mar; 26(3):318-327. PMID: 31859547.
    Citations:    Fields:    Translation:Humans
  18. Hudalla H, Michael Z, Christodoulou N, Willis GR, Fernandez-Gonzalez A, Filatava EJ, Dieffenbach P, Fredenburgh LE, Stearman RS, Geraci MW, Kourembanas S, Christou H. Carbonic Anhydrase Inhibition Ameliorates Inflammation and Experimental Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2019 10; 61(4):512-524. PMID: 30951642; PMCID: PMC6775956.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  19. DiPrisco B, Kumar A, Kalra B, Savjani GV, Michael Z, Farr O, Papathanasiou AE, Christou H, Mantzoros C. Placental proteases PAPP-A and PAPP-A2, the binding proteins they cleave (IGFBP-4 and -5), and IGF-I and IGF-II: Levels in umbilical cord blood and associations with birth weight and length. Metabolism. 2019 11; 100:153959. PMID: 31401027.
    Citations: 7     Fields:    Translation:HumansCells
  20. Lithoxopoulou M, Rallis D, Christou H, Goutsiou E, Varaklioti A, Karagianni P, Tsakalidis C, Domeyer P, Kuriakeli G, Soubasi V. Early caloric deprivation in preterm infants affects Bayley-III scales performance at 18-24 months of corrected age. Res Dev Disabil. 2019 Aug; 91:103429. PMID: 31272067.
    Citations: 2     Fields:    Translation:Humans
  21. Michael Z, Spyropoulos F, Ghanta S, Christou H. Bronchopulmonary Dysplasia: An Update of Current Pharmacologic Therapies and New Approaches. Clin Med Insights Pediatr. 2018; 12:1179556518817322. PMID: 30574005; PMCID: PMC6295761.
    Citations: 30     
  22. Liang X, Gupta K, Quintero JR, Cernadas M, Kobzik L, Christou H, Pier GB, Owen CA, Çataltepe S. Macrophage FABP4 is required for neutrophil recruitment and bacterial clearance in Pseudomonas aeruginosa pneumonia. FASEB J. 2019 03; 33(3):3562-3574. PMID: 30462529; PMCID: PMC6988858.
    Citations: 11     Fields:    Translation:AnimalsCells
  23. Scheid A, Borriello F, Pietrasanta C, Christou H, Diray-Arce J, Pettengill MA, Joshi S, Li N, Bergelson I, Kollmann T, Dowling DJ, Levy O. Adjuvant Effect of Bacille Calmette-Guérin on Hepatitis B Vaccine Immunogenicity in the Preterm and Term Newborn. Front Immunol. 2018; 9:29. PMID: 29416539.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  24. Angelidou A, Michael Z, Hotz A, Friedman K, Emani S, LaRovere K, Christou H. Is There More to Zika? Complex Cardiac Disease in a Case of Congenital Zika Syndrome. Neonatology. 2018; 113(2):177-182. PMID: 29248924.
    Citations: 7     Fields:    Translation:HumansCells
  25. Christou H, Hudalla H, Michael Z, Filatava EJ, Li J, Zhu M, Possomato-Vieira JS, Dias-Junior C, Kourembanas S, Khalil RA. Impaired Pulmonary Arterial Vasoconstriction and Nitric Oxide-Mediated Relaxation Underlie Severe Pulmonary Hypertension in the Sugen-Hypoxia Rat Model. J Pharmacol Exp Ther. 2018 02; 364(2):258-274. PMID: 29212831; PMCID: PMC5774216.
    Citations: 12     Fields:    Translation:AnimalsCells
  26. Joung KE, Cataltepe SU, Michael Z, Christou H, Mantzoros CS. Cord Blood Adipocyte Fatty Acid-Binding Protein Levels Correlate With Gestational Age and Birth Weight in Neonates. J Clin Endocrinol Metab. 2017 05 01; 102(5):1606-1613. PMID: 28324040; PMCID: PMC5443332.
    Citations: 7     Fields:    Translation:Humans
  27. Christou H, Dookeran N, Haas A, Di Frances C, Emans SJ, Milstein ME, Kram KE, Seely EW. Establishing Effective Mentoring Networks: Rationale and Strategies. MedEdPORTAL. 2017 Apr 18; 13:10571. PMID: 30800773; PMCID: PMC6338153.
    Citations: 1     Fields:    
  28. Joung KE, Burris HH, Van Marter LJ, McElrath TF, Michael Z, Tabatabai P, Litonjua AA, Weiss ST, Christou H. Vitamin D and bronchopulmonary dysplasia in preterm infants. J Perinatol. 2016 10; 36(10):878-82. PMID: 27467562.
    Citations: 15     Fields:    Translation:Humans
  29. Christou H, Dizon ML, Farrow KN, Jadcherla SR, Leeman KT, Maheshwari A, Rubin LP, Stansfield BK, Rowitch DH. Sustaining careers of physician-scientists in neonatology and pediatric critical care medicine: formulating supportive departmental policies. Pediatr Res. 2016 11; 80(5):635-640. PMID: 27434118.
    Citations: 3     Fields:    Translation:Humans
  30. Joung KE, Park KH, Filippaios A, Dincer F, Christou H, Mantzoros CS. Cord blood irisin levels are positively correlated with birth weight in newborn infants. Metabolism. 2015 Nov; 64(11):1507-14. PMID: 26303870; PMCID: PMC5348079.
    Citations: 13     Fields:    Translation:Humans
  31. Lin T, Maita D, Thundivalappil SR, Riley FE, Hambsch J, Van Marter LJ, Christou HA, Berra L, Fagan S, Christiani DC, Warren HS. Hemopexin in severe inflammation and infection: mouse models and human diseases. Crit Care. 2015 Apr 15; 19:166. PMID: 25888135.
    Citations: 16     Fields:    Translation:HumansAnimals
  32. Tsoyi K, Geldart AM, Christou H, Liu X, Chung SW, Perrella MA. Elk-3 is a KLF4-regulated gene that modulates the phagocytosis of bacteria by macrophages. J Leukoc Biol. 2015 Jan; 97(1):171-80. PMID: 25351511; PMCID: PMC4377825.
    Citations: 14     Fields:    Translation:AnimalsCells
  33. Joung KE, Christou H, Park KH, Mantzoros CS. Cord blood levels of osteopontin as a phenotype marker of gestational age and neonatal morbidities. Obesity (Silver Spring). 2014 May; 22(5):1317-24. PMID: 24123979.
    Citations: 4     Fields:    Translation:Humans
  34. Burris HH, Van Marter LJ, McElrath TF, Tabatabai P, Litonjua AA, Weiss ST, Christou H. Vitamin D status among preterm and full-term infants at birth. Pediatr Res. 2014 Jan; 75(1-1):75-80. PMID: 24121425.
    Citations: 36     Fields:    Translation:Humans
  35. Xiao Y, Christou H, Liu L, Visner G, Mitsialis SA, Kourembanas S, Liu H. Endothelial indoleamine 2,3-dioxygenase protects against development of pulmonary hypertension. Am J Respir Crit Care Med. 2013 Aug 15; 188(4):482-91. PMID: 23822766; PMCID: PMC3778740.
    Citations: 27     Fields:    Translation:AnimalsCells
  36. Ghanta S, Leeman KT, Christou H. An update on pharmacologic approaches to bronchopulmonary dysplasia. Semin Perinatol. 2013 Apr; 37(2):115-23. PMID: 23582966.
    Citations: 14     Fields:    Translation:Humans
  37. Christou H, Reslan OM, Mam V, Tanbe AF, Vitali SH, Touma M, Arons E, Mitsialis SA, Kourembanas S, Khalil RA. Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2012 May 01; 302(9):L875-90. PMID: 22287610.
    Citations: 13     Fields:    Translation:AnimalsCells
  38. Tropea K, Christou H. Current pharmacologic approaches for prevention and treatment of bronchopulmonary dysplasia. Int J Pediatr. 2012; 2012:598606. PMID: 22262977.
    Citations: 7     
  39. Brenninkmeijer L, Kuehl C, Geldart AM, Arons E, Christou H. Heme oxygenase-1 does not mediate the effects of extracellular acidosis on vascular smooth muscle cell proliferation, migration, and susceptibility to apoptosis. J Vasc Res. 2011; 48(4):285-96. PMID: 21273783.
    Citations: 10     Fields:    Translation:AnimalsCells
  40. Christou HA, Khalil RA. Sex hormones and vascular protection in pulmonary arterial hypertension. J Cardiovasc Pharmacol. 2010 Nov; 56(5):471-4. PMID: 20881609.
    Citations: 5     Fields:    Translation:HumansAnimals
  41. Mam V, Tanbe AF, Vitali SH, Arons E, Christou HA, Khalil RA. Impaired vasoconstriction and nitric oxide-mediated relaxation in pulmonary arteries of hypoxia- and monocrotaline-induced pulmonary hypertensive rats. J Pharmacol Exp Ther. 2010 Feb; 332(2):455-62. PMID: 19915069.
    Citations: 34     Fields:    Translation:Animals
  42. Vitali SH, Mitsialis SA, Liang OD, Liu X, Fernandez-Gonzalez A, Christou H, Wu X, McGowan FX, Kourembanas S. Divergent cardiopulmonary actions of heme oxygenase enzymatic products in chronic hypoxia. PLoS One. 2009 Jun 19; 4(6):e5978. PMID: 19543386.
    Citations: 15     Fields:    Translation:AnimalsCells
  43. Aslam M, Christou HA. Intrauterine closure of the ductus arteriosus: implications for the neonatologist. Am J Perinatol. 2009 Aug; 26(7):473-8. PMID: 19263336.
    Citations: 1     Fields:    Translation:Humans
  44. Guan J, Wu X, Arons E, Christou H. The p38 mitogen-activated protein kinase pathway is involved in the regulation of heme oxygenase-1 by acidic extracellular pH in aortic smooth muscle cells. J Cell Biochem. 2008 Dec 01; 105(5):1298-306. PMID: 18846504; PMCID: PMC2588478.
    Citations: 12     Fields:    Translation:AnimalsCells
  45. Waisbren SE, Bowles H, Hasan T, Zou KH, Emans SJ, Goldberg C, Gould S, Levine D, Lieberman E, Loeken M, Longtine J, Nadelson C, Patenaude AF, Quinn D, Randolph AG, Solet JM, Ullrich N, Walensky R, Weitzman P, Christou H. Gender differences in research grant applications and funding outcomes for medical school faculty. J Womens Health (Larchmt). 2008 Mar; 17(2):207-14. PMID: 18321172.
    Citations: 36     Fields:    Translation:Humans
  46. Baveja R, Christou H. Pharmacological strategies in the prevention and management of bronchopulmonary dysplasia. Semin Perinatol. 2006 Aug; 30(4):209-18. PMID: 16860161.
    Citations: 18     Fields:    Translation:Humans
  47. Anttila V, Christou H, Hagino I, Iwata Y, Mettler BA, Fernandez-Gonzalez A, Zurakowski D, Jonas RA. Cerebral endothelial nitric oxide synthase expression is reduced after very-low-flow bypass. Ann Thorac Surg. 2006 Jun; 81(6):2202-6. PMID: 16731155.
    Citations: 3     Fields:    Translation:Animals
  48. Vitali SH, Mitsialis SA, Christou H, Fernandez-Gonzalez A, Liu X, Kourembanas S. Mechanisms of heme oxygenase-1-mediated cardiac and pulmonary vascular protection in chronic hypoxia: roles of carbon monoxide and bilirubin. Chest. 2005 Dec; 128(6 Suppl):578S-579S. PMID: 16373841.
    Citations: 2     Fields:    Translation:Animals
  49. Christou H, Brodsky D. Lung injury and bronchopulmonary dysplasia in newborn infants. J Intensive Care Med. 2005 Mar-Apr; 20(2):76-87. PMID: 15855220.
    Citations: 7     Fields:    Translation:HumansAnimals
  50. Christou H, Bailey N, Kluger MS, Mitsialis SA, Kourembanas S. Extracellular acidosis induces heme oxygenase-1 expression in vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2005 Jun; 288(6):H2647-52. PMID: 15681695.
    Citations: 11     Fields:    Translation:AnimalsCells
  51. Brodsky D, Christou H. Current concepts in intrauterine growth restriction. J Intensive Care Med. 2004 Nov-Dec; 19(6):307-19. PMID: 15523117.
    Citations: 72     Fields:    Translation:Humans
  52. Hossain T, Kappelman MD, Perez-Atayde AR, Young GJ, Huttner KM, Christou H. Primary ciliary dyskinesia as a cause of neonatal respiratory distress: implications for the neonatologist. J Perinatol. 2003 Dec; 23(8):684-7. PMID: 14647169.
    Citations: 9     Fields:    Translation:HumansCells
  53. Christou H, Serdy S, Mantzoros CS. Leptin in relation to growth and developmental processes in the fetus. Semin Reprod Med. 2002 May; 20(2):123-30. PMID: 12087497.
    Citations: 8     Fields:    Translation:HumansAnimals
  54. Minamino T, Christou H, Hsieh CM, Liu Y, Dhawan V, Abraham NG, Perrella MA, Mitsialis SA, Kourembanas S. Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8798-803. PMID: 11447290; PMCID: PMC37515.
    Citations: 126     Fields:    Translation:HumansAnimals
  55. Christou H, Connors JM, Ziotopoulou M, Hatzidakis V, Papathanassoglou E, Ringer SA, Mantzoros CS. Cord blood leptin and insulin-like growth factor levels are independent predictors of fetal growth. J Clin Endocrinol Metab. 2001 Feb; 86(2):935-8. PMID: 11158070.
    Citations: 44     Fields:    Translation:Humans
  56. Christou H, Van Marter LJ, Wessel DL, Allred EN, Kane JW, Thompson JE, Stark AR, Kourembanas S. Inhaled nitric oxide reduces the need for extracorporeal membrane oxygenation in infants with persistent pulmonary hypertension of the newborn. Crit Care Med. 2000 Nov; 28(11):3722-7. PMID: 11098980.
    Citations: 24     Fields:    Translation:HumansCTClinical Trials
  57. Christou H, Morita T, Hsieh CM, Koike H, Arkonac B, Perrella MA, Kourembanas S. Prevention of hypoxia-induced pulmonary hypertension by enhancement of endogenous heme oxygenase-1 in the rat. Circ Res. 2000 Jun 23; 86(12):1224-9. PMID: 10864912.
    Citations: 68     Fields:    Translation:Animals
  58. Yet SF, Perrella MA, Layne MD, Hsieh CM, Maemura K, Kobzik L, Wiesel P, Christou H, Kourembanas S, Lee ME. Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice. J Clin Invest. 1999 Apr; 103(8):R23-9. PMID: 10207174; PMCID: PMC408281.
    Citations: 129     Fields:    Translation:Animals
  59. Christou H, Magnani B, Morse DS, Allred EN, Van Marter LJ, Wessel DL, Kourembanas S. Inhaled nitric oxide does not affect adenosine 5'-diphosphate-dependent platelet activation in infants with persistent pulmonary hypertension of the newborn. Pediatrics. 1998 Dec; 102(6):1390-3. PMID: 9832574.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  60. Kourembanas S, Morita T, Christou H, Liu Y, Koike H, Brodsky D, Arthur V, Mitsial SA. Hypoxic responses of vascular cells. Chest. 1998 Jul; 114(1 Suppl):25S-28S. PMID: 9676610.
    Citations: 7     Fields:    Translation:HumansAnimals
  61. Liu Y, Christou H, Morita T, Laughner E, Semenza GL, Kourembanas S. Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5' enhancer. J Biol Chem. 1998 Jun 12; 273(24):15257-62. PMID: 9614141.
    Citations: 33     Fields:    Translation:AnimalsCells
  62. Christou H, Yoshida A, Arthur V, Morita T, Kourembanas S. Increased vascular endothelial growth factor production in the lungs of rats with hypoxia-induced pulmonary hypertension. Am J Respir Cell Mol Biol. 1998 Jun; 18(6):768-76. PMID: 9618381.
    Citations: 40     Fields:    Translation:Animals
  63. Christou H, Adatia I, Van Marter LJ, Kane JW, Thompson JE, Stark AR, Wessel DL, Kourembanas S. Effect of inhaled nitric oxide on endothelin-1 and cyclic guanosine 5'-monophosphate plasma concentrations in newborn infants with persistent pulmonary hypertension. J Pediatr. 1997 Apr; 130(4):603-11. PMID: 9108859.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  64. Kourembanas S, Morita T, Liu Y, Christou H. Mechanisms by which oxygen regulates gene expression and cell-cell interaction in the vasculature. Kidney Int. 1997 Feb; 51(2):438-43. PMID: 9027718.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
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