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Ning Y, Zhou IY, Roberts JD, Rotile NJ, Akam E, Barrett SC, Sojoodi M, Barr MN, Punshon T, Pantazopoulos P, Drescher HK, Jackson BP, Tanabe KK, Caravan P. Molecular MRI quantification of extracellular aldehyde pairs for early detection of liver fibrogenesis and response to treatment. Sci Transl Med. 2022 Sep 21; 14(663):eabq6297.
PMID: 36130015.
Citations: Fields:
Translation:
HumansAnimals
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Kulkarni K, Nichols JH, Armoundas AA, Roberts JD. RespiCo: A novel, flexible, and stand-alone electronic respiratory coaching device. HardwareX. 2022 Oct; 12:e00335.
PMID: 35873736; PMCID: PMC9304670.
Citations:
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Berra L, Falke KJ, Francis RCE, Roberts JD, Chiche JD. In memoriam: Warren M. Zapol. Intensive Care Med. 2022 Mar; 48(3):383-385.
PMID: 35061052.
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Zhong Y, Mahoney RC, Khatun Z, Chen HH, Nguyen CT, Caravan P, Roberts JD. Lysyl oxidase regulation and protein aldehydes in the injured newborn lung. Am J Physiol Lung Cell Mol Physiol. 2022 02 01; 322(2):L204-L223.
PMID: 34878944; PMCID: PMC8794022.
Citations: Fields:
Translation:
AnimalsCells
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Kulkarni K, Sevakula RK, Kassab MB, Nichols J, Roberts JD, Isselbacher EM, Armoundas AA. Ambulatory monitoring promises equitable personalized healthcare delivery in underrepresented patients. Eur Heart J Digit Health. 2021 Sep; 2(3):494-510.
PMID: 34604759.
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Kulkarni K, Awasthi N, Roberts JD, Armoundas AA. Utility of a Smartphone-Based System (cvrPhone) in Estimating Minute Ventilation from Electrocardiographic Signals. Telemed J E Health. 2021 12; 27(12):1433-1439.
PMID: 33729001; PMCID: PMC8742262.
Citations:
1 Fields:
Translation:
Animals
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Zhong Y, Bry K, Roberts JD. IL-1ß dysregulates cGMP signaling in the newborn lung. Am J Physiol Lung Cell Mol Physiol. 2020 May 06.
PMID: 32374672.
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Shvedova M, Litvak MM, Roberts JD, Fukumura D, Suzuki T, Sencan I, Li G, Reventun P, Buys ES, Kim HH, Sakadžic S, Ayata C, Huang PL, Feil R, Atochin DN. cGMP-dependent protein kinase I in vascular smooth muscle cells improves ischemic stroke outcome in mice. J Cereb Blood Flow Metab. 2019 12; 39(12):2379-2391.
PMID: 31423931.
Citations:
2 Fields:
Translation:
AnimalsCells
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Sohn K, Merchant FM, Abohashem S, Kulkarni K, Singh JP, Heist EK, Owen C, Roberts JD, Isselbacher EM, Sana F, Armoundas AA. Utility of a smartphone based system (cvrphone) to accurately determine apneic events from electrocardiographic signals. PLoS One. 2019; 14(6):e0217217.
PMID: 31206522.
Citations:
5 Fields:
Translation:
Animals
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Du L, Roberts JD. Transforming growth factor-ß downregulates sGC subunit expression in pulmonary artery smooth muscle cells via MEK and ERK signaling. Am J Physiol Lung Cell Mol Physiol. 2019 01 01; 316(1):L20-L34.
PMID: 30260287; PMCID: PMC6383502.
Citations:
4 Fields:
Translation:
AnimalsCells
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Zhang H, Du L, Zhong Y, Flanders KC, Roberts JD. Transforming growth factor-ß stimulates Smad1/5 signaling in pulmonary artery smooth muscle cells and fibroblasts of the newborn mouse through ALK1. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 01; 313(3):L615-L627.
PMID: 28642261; PMCID: PMC5625261.
Citations:
16 Fields:
Translation:
HumansAnimalsCells
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Kato S, Chen J, Cornog KH, Zhang H, Roberts JD. The Golgi apparatus regulates cGMP-dependent protein kinase I compartmentation and proteolysis. Am J Physiol Cell Physiol. 2015 Jun 01; 308(11):C944-58.
PMID: 25855081; PMCID: PMC4451346.
Citations:
4 Fields:
Translation:
HumansAnimalsCells
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Chen J, Roberts JD. cGMP-dependent protein kinase I gamma encodes a nuclear localization signal that regulates nuclear compartmentation and function. Cell Signal. 2014 Dec; 26(12):2633-44.
PMID: 25172423.
Citations:
5 Fields:
Translation:
AnimalsCells
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Coté CJ, Sui J, Anderson TA, Bhattacharya ST, Shank ES, Tuason PM, August DA, Zibaitis A, Firth PG, Fuzaylov G, Leeman MR, Mai CL, Roberts JD. Continuous noninvasive cardiac output in children: is this the next generation of operating room monitors? Initial experience in 402 pediatric patients. Paediatr Anaesth. 2015 Feb; 25(2):150-9.
PMID: 24916144.
Citations:
8 Fields:
Translation:
Humans
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Witsch TJ, Niess G, Sakkas E, Likhoshvay T, Becker S, Herold S, Mayer K, Vadász I, Roberts JD, Seeger W, Morty RE. Transglutaminase 2: a new player in bronchopulmonary dysplasia? Eur Respir J. 2014 Jul; 44(1):109-21.
PMID: 24603819; PMCID: PMC4212268.
Citations:
10 Fields:
Translation:
HumansAnimalsCells
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Pieretti AC, Ahmed AM, Roberts JD, Kelleher CM. A novel in vitro model to study alveologenesis. Am J Respir Cell Mol Biol. 2014 Feb; 50(2):459-69.
PMID: 24066869.
Citations:
17 Fields:
Translation:
AnimalsCells
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Bachiller PR, Cornog KH, Kato R, Buys ES, Roberts JD. Soluble guanylate cyclase modulates alveolarization in the newborn lung. Am J Physiol Lung Cell Mol Physiol. 2013 Oct 15; 305(8):L569-81.
PMID: 23934926.
Citations:
17 Fields:
Translation:
AnimalsCells
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Kato S, Zhang R, Roberts JD. Proprotein convertases play an important role in regulating PKGI endoproteolytic cleavage and nuclear transport. Am J Physiol Lung Cell Mol Physiol. 2013 Jul 15; 305(2):L130-40.
PMID: 23686857.
Citations:
7 Fields:
Translation:
HumansAnimalsCells
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Witsch TJ, Turowski P, Sakkas E, Niess G, Becker S, Herold S, Mayer K, Vadász I, Roberts JD Jr, Seeger W, Morty RE. . Deregulation of the lysyl hydroxylase matrix cross-linking system in experimental and clinical bronchopulmonary dysplasia. Am J Respir Cell Mol Biol. 2013; 3(306):L246-59.
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Shen D, Li J, Lepore JJ, Anderson TJ, Sinha S, Lin AY, Cheng L, Cohen ED, Roberts JD, Dedhar S, Parmacek MS, Gerszten RE. Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells. Circ Res. 2011 Sep 02; 109(6):616-28.
PMID: 21778429; PMCID: PMC3351207.
Citations:
18 Fields:
Translation:
AnimalsCells
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Bachiller PR, Nakanishi H, Roberts JD. Transforming growth factor-beta modulates the expression of nitric oxide signaling enzymes in the injured developing lung and in vascular smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2010 Mar; 298(3):L324-34.
PMID: 20023176.
Citations:
17 Fields:
Translation:
HumansAnimalsCells
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Sugiura T, Nakanishi H, Roberts JD. Proteolytic processing of cGMP-dependent protein kinase I mediates nuclear cGMP signaling in vascular smooth muscle cells. Circ Res. 2008 Jul 03; 103(1):53-60.
PMID: 18535260.
Citations:
10 Fields:
Translation:
AnimalsCells
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Roberts JD, Chiche JD, Kolpa EM, Bloch DB, Bloch KD. cGMP-dependent protein kinase I interacts with TRIM39R, a novel Rpp21 domain-containing TRIM protein. Am J Physiol Lung Cell Mol Physiol. 2007 Oct; 293(4):L903-12.
PMID: 17601797.
Citations:
4 Fields:
Translation:
HumansAnimalsCells
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Bloch KD, Ichinose F, Roberts JD, Zapol WM. Inhaled NO as a therapeutic agent. Cardiovasc Res. 2007 Jul 15; 75(2):339-48.
PMID: 17544387; PMCID: PMC1986790.
Citations:
46 Fields:
Translation:
HumansAnimals
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Nakanishi H, Sugiura T, Streisand JB, Lonning SM, Roberts JD. TGF-beta-neutralizing antibodies improve pulmonary alveologenesis and vasculogenesis in the injured newborn lung. Am J Physiol Lung Cell Mol Physiol. 2007 Jul; 293(1):L151-61.
PMID: 17400601.
Citations:
69 Fields:
Translation:
AnimalsCells
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Heller EA, Liu E, Tager AM, Sinha S, Roberts JD, Koehn SL, Libby P, Aikawa ER, Chen JQ, Huang P, Freeman MW, Moore KJ, Luster AD, Gerszten RE. Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment. Circulation. 2005 Jul 26; 112(4):578-86.
PMID: 16043658.
Citations:
47 Fields:
Translation:
AnimalsCells
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Nakajjima A, Yu J, Roberts JD Jr, Kieff E, Bloch KD, Bloch DB. Sp100 bridges PML- and Sp140-containing nuclear bodies; disruption of these domains by Epstein Barr virus leader protein. Journal of Biochemistry. 2005; in review.
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Roberts JD Jr, Kolpa E, Chiche J-D, Bloch D, Bloch K. PKG interacts with and phosphorylates novel ring finger proteins expressed in the lung. Journal of Biological Chemistry. 2005; in preparation.
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Ichinose F, Roberts JD, Zapol WM. Inhaled nitric oxide: a selective pulmonary vasodilator: current uses and therapeutic potential. Circulation. 2004 Jun 29; 109(25):3106-11.
PMID: 15226227.
Citations:
69 Fields:
Translation:
Humans
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Roberts JD Jr. Protective mechanisms of inhaled NO in the newborn lung. Journal of Perinatal Medicine. 2003; 31:79.
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Hellman J, Roberts JD, Tehan MM, Allaire JE, Warren HS. Bacterial peptidoglycan-associated lipoprotein is released into the bloodstream in gram-negative sepsis and causes inflammation and death in mice. J Biol Chem. 2002 Apr 19; 277(16):14274-80.
PMID: 11830585.
Citations:
38 Fields:
Translation:
AnimalsCells
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Roberts JD Jr, Cromin J, Zestos MM. Anesthesia for surgical emergencies in the neonate. In: Clinical anestehsia procedures of the Massachusetts General Hospital, Hurford W, ed. 2002; 445-466.
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Hellman J, Roberts JD Jr, Tehan MM, Allaire J, Warren HS. Bacterial peptidoglycan-associated lipoprotein circulates in septic mice and has potent inflammatory effects. Journal of Biologicl Chemistry. 2002; 277:14374-14280.
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Roberts JD Jr, Cronin J, Todres JD. Neonatal emergencies. In: A practice of anesthesia for infants and children, Cote CJ, Todres ID, Goudsouzian NG, Ryan JF, eds. 2001; 294-314.
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Roberts JD, Chiche JD, Weimann J, Steudel W, Zapol WM, Bloch KD. Nitric oxide inhalation decreases pulmonary artery remodeling in the injured lungs of rat pups. Circ Res. 2000 Jul 21; 87(2):140-5.
PMID: 10903998.
Citations:
12 Fields:
Translation:
Animals
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Roberts JD, Zapol WM. Inhaled nitric oxide. Semin Perinatol. 2000 Feb; 24(1):55-8.
PMID: 10709861.
Citations:
1 Fields:
Translation:
HumansAnimals
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Lee K-H, Roberts JD Jr, Matsui T, Li L, Gianetti J, Blocj KD, Rosenzweig A. Inhated nitric oxide reduces myocardial infarct size after transient ischemia without affecting systemic hemodynamics. Circulation. 2000; 102:II-60.
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Zestos MM, Insoft R, Roberts JD Jr. Neonatal intensive care. In: Postoperative critical care procedures of the Massachusetts General Hospital, Hurfors W, ed. 2000.
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Catlin EA, Roberts JD Jr, Erana R, Preffer FI, Ferry JA, Kelliher AS, Atkins L, Weinstein HJ. Vertical transmission of an aggressive natural killer cell lymphoma/leukemia. The New England Journal of Medicine. 1999; 341:80-91.
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Chiche J-D, Schlutsmeyer SM, Bloch DB, de la Monte SM, Roberts JD Jr, Filippov G, Janssens SP, Rosenzweig A, Bloch KD. Restoration of cGMP-dependent protein kinase activity increases the sensitivity of vascular smooth muscle cells to the antiproliferative and pro-apoptotic effect of nitric oxide / cGMP. Journal of Biology Chemistry. 1998; 273:34263-34271.
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Zestos MM, Roberts JD Jr. Anesthesia for neonatal surgery. In: Clinical anesthesia procedures of the Massachusetts General Hospital, Hurford W, Balin MT, Davidson JK, et.al., eds. 1998; 472-498.
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Roberts JD, Fineman JR, Morin FC, Shaul PW, Rimar S, Schreiber MD, Polin RA, Zwass MS, Zayek MM, Gross I, Heymann MA, Zapol WM. Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The Inhaled Nitric Oxide Study Group. N Engl J Med. 1997 Feb 27; 336(9):605-10.
PMID: 9032045.
Citations:
142 Fields:
Translation:
HumansCTClinical Trials
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Roberts JD Jr. Nitric oxide and the perinatal circulation. In: Fetal and Neonatal Physiology, Polin, Fox, eds. 1997.
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Lee JS, Adrie C, Jacob HJ, Roberts JD Jr, Zapol WM, Bloch KD. Chronic inhalation of nitric oxide inhibits neointimal formation after balloon arterial injury. Circulation Reserarch. 1996; 78:337-342.
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Roberts JD Jr, Kinsella JP, Abman SH. Inhaled nitric oxide in neonatal pulmonary hypertension and severe respiratory distress syndrome: experimental and clinical studies. In: Nitric Oxide and Lung, Zapol WM, Bloch KD, eds. 1996.
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Roberts JD Jr, Bloch KD. Alternate splicing of the vascular endothelial growth factor mRNA is modulated during lung development. Pediatric Research. 1996; 39:241A.
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Bloch KD, Wolfram JR, Brown DM, Roberts JD, Zapol DG, Lepore JJ, Filippov G, Thomas JE, Jacob HJ, Bloch DB. Three members of the nitric oxide synthase II gene family (NOS2A, NOS2B, and NOS2C) colocalize to human chromosome 17. Genomics. 1995 Jun 10; 27(3):526-30.
PMID: 7558036.
Citations:
10 Fields:
Translation:
HumansAnimalsCells
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Roberts JD, Roberts CT, Jones RC, Zapol WM, Bloch KD. Continuous nitric oxide inhalation reduces pulmonary arterial structural changes, right ventricular hypertrophy, and growth retardation in the hypoxic newborn rat. Circ Res. 1995 Feb; 76(2):215-22.
PMID: 7834832.
Citations:
25 Fields:
Translation:
Animals
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Bigatello LM, Hurford WE, Kacmarek RM, Roberts JD, Zapol WM. Prolonged inhalation of low concentrations of nitric oxide in patients with severe adult respiratory distress syndrome. Effects on pulmonary hemodynamics and oxygenation. Anesthesiology. 1994 Apr; 80(4):761-70.
PMID: 8024129.
Citations:
27 Fields:
Translation:
HumansCTClinical Trials
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Stanek KS, Roberts JD Jr, Zapol WM, Falke KJ, Liggins GC, Liggins L. Thoracic circumference and nitric oxide activity in the free-diving Weddell seal. The Antarctic Journal. 1994; 29:172-174.
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Roberts JD JR, Abman SH. Physiology of nitric oxide in the perinatal lung. In: New Therapies for neonatal respiratory failure, Boynton, ed. 1994.
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Zayek M, Wild L, Roberts JD, Morin FC. Effect of nitric oxide on the survival rate and incidence of lung injury in newborn lambs with persistent pulmonary hypertension. J Pediatr. 1993 Dec; 123(6):947-52.
PMID: 8229529.
Citations:
9 Fields:
Translation:
Animals
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Roberts JD. Inhaled nitric oxide for treatment of pulmonary artery hypertension in the newborn and infant. Crit Care Med. 1993 Sep; 21(9 Suppl):S374-6.
PMID: 8365236.
Citations:
2 Fields:
Translation:
HumansAnimals
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Roberts JD, Lang P, Bigatello LM, Vlahakes GJ, Zapol WM. Inhaled nitric oxide in congenital heart disease. Circulation. 1993 Feb; 87(2):447-53.
PMID: 8425292.
Citations:
40 Fields:
Translation:
Humans
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Roberts JD, Chen TY, Kawai N, Wain J, Dupuy P, Shimouchi A, Bloch K, Polaner D, Zapol WM. Inhaled nitric oxide reverses pulmonary vasoconstriction in the hypoxic and acidotic newborn lamb. Circ Res. 1993 Feb; 72(2):246-54.
PMID: 8380356.
Citations:
16 Fields:
Translation:
Animals
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Roberts JD Jr, Shaul P. Persistent pulmonary hypertesion of the newborn: recent advances in diagnosis and treatment. In: Pediatric Clinical North America, Hageman, ed. 1993; 983-1004.
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Roberts JD, Polaner DM, Lang P, Zapol WM. Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet. 1992 Oct 03; 340(8823):818-9.
PMID: 1357245.
Citations:
105 Fields:
Translation:
Humans
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Roberts JD Jr, Todres ID, Cote CJ. Neonatal emergencies. In: A practice of anesthesia for infants and children, Cote CJ, Ryan JF, Todres ID, Goudsouzian NG, eds. 1992; 225-246.
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Roberts JD Jr. Duodenal atresia and trisomy 21. In: Common problems in pediatric anesthesia, Stehling L, ed. 1992; 39-43.
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Roberts JD Jr, Todres ID. Pediatric cardiopulmonary resuscitation. In: Postoperative critical care procedures of the Massachusetts General Hospital, Hoffman W, Wasnick J, eds. 1992; 397-403.
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Roberts JD Jr, Todres ID, Cote CJ. Neonatal emergencies. A practice of anesthesia for infants and children. Cote CJ, Ryan JF, Todres ID, Goudsouzian NE, eds. 1992; 225-246.
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Soll RF, Hoekstra RE, Fangman JJ, Corbet AJ, Adams JM, James LS, Schulze K, Oh W, Roberts JD, Dorst JP, et al. Multicenter trial of single-dose modified bovine surfactant extract (Survanta) for prevention of respiratory distress syndrome. Ross Collaborative Surfactant Prevention Study Group. Pediatrics. 1990 Jun; 85(6):1092-102.
PMID: 2187176.
Citations:
16 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Roberts JD, Oh W. Pulmonary oxygen toxicity in the guinea pig. Effect of indomethacin. Dev Pharmacol Ther. 1989; 12(2):106-12.
PMID: 2714157.
Citations: Fields:
Translation:
Animals
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Voha BR, Garcia-Coll C, Roberts JD Jr, Brown LJ, Oh W. Decreased morbidities during the first year in very low birth weight (<1200 grams) infants treated with single dose Surfactant-TA (STA) for prevention of RDS. Pediatric Research. 1989; 25:1393A.
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Ogburn PL Jr, Roberts JR Jr, Dassopoulos T, Walker JL. Leukotriene B$ 6-Keto-prostaglandin F1, thromboxane B2, and free arachidonic acid levels in human placental tissue. Ann. NY Acad. Sci. 1988; 524:434-435.
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Roberts JD Jr, Jalowayski A, Merritt TA. Reduction of cord blood polymorphonuclear (PMN) leukocyte chemotaxis by indomethacin. Pediatric Research. 1985; 19:381A.
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Roberts JD Jr. Pulmonary surfactant metabolism [Master's]. 1982.
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Roberts JD Jr, Zmora E, Merritt TA. Unidimensional TLC for resolution of amniotic fluid phospholipids. Pediatric Research. 1980; 14:609A.