Harvard Catalyst Profiles

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Donald Mark Coen, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AI141940 (COEN, DONALD M) Nov 9, 2018 - Oct 31, 2020
    NIH/NIAID
    Structural studies of herpesvirus DNA polymerases
    Role: Principal Investigator
  2. P01AI098681 (COEN, DONALD M) Jul 2, 2013 - Jun 30, 2018
    NIH/NIAID
    Viral And host mechanisms that tilt the HSV lytic/latent balance
    Role: Principal Investigator
  3. R21AI105896 (COEN, DONALD M) Mar 1, 2013 - Feb 28, 2015
    NIH/NIAID
    Antagonizing miRNAs in a strategy to cure HSV latency
    Role: Principal Investigator
  4. P01NS035138 (COEN, DONALD M) May 1, 1996 - Aug 31, 2012
    NIH/NINDS
    Mechanism of Latency of Herpes Simplex Virus
    Role: Principal Investigator
  5. U01AI033357 (COEN, DONALD M) Aug 1, 1992 - Jul 31, 1995
    NIH/NIAID
    ANTICMV DRUGS VIA MOLECULAR STUDIES OF CMV DRUG TARGETS
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lawler JL, Coen DM. HSV-1 DNA polymerase 3'-5' exonuclease-deficient mutant D368A exhibits severely reduced viral DNA synthesis and polymerase expression. J Gen Virol. 2018 Oct; 99(10):1432-1437. PMID: 30176164.
    Citations:    Fields:    
  2. Wilkie AR, Sharma M, Pesola JM, Ericsson M, Fernandez R, Coen DM. A Role for Myosin Va in Human Cytomegalovirus Nuclear Egress. J Virol. 2018 03 15; 92(6). PMID: 29298889.
    Citations:    Fields:    Translation:HumansCells
  3. Lawler JL, Mukherjee P, Coen DM. Herpes Simplex Virus 1 DNA Polymerase RNase H Activity Acts in a 3'-to-5' Direction and Is Dependent on the 3'-to-5' Exonuclease Active Site. J Virol. 2018 03 01; 92(5). PMID: 29237844.
    Citations:    Fields:    Translation:Cells
  4. Lee JS, Raja P, Pan D, Pesola JM, Coen DM, Knipe DM. CCCTC-Binding Factor Acts as a Heterochromatin Barrier on Herpes Simplex Viral Latent Chromatin and Contributes to Poised Latent Infection. MBio. 2018 02 06; 9(1). PMID: 29437926.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  5. Lutz G, Jurak I, Kim ET, Kim JY, Hackenberg M, Leader A, Stoller ML, Fekete DM, Weitzman MD, Coen DM, Wilson AC. Viral Ubiquitin Ligase Stimulates Selective Host MicroRNA Expression by Targeting ZEB Transcriptional Repressors. Viruses. 2017 08 07; 9(8). PMID: 28783105.
    Citations:    Fields:    Translation:HumansCells
  6. Lye MF, Wilkie AR, Filman DJ, Hogle JM, Coen DM. Getting to and through the inner nuclear membrane during herpesvirus nuclear egress. Curr Opin Cell Biol. 2017 06; 46:9-16. PMID: 28086162.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  7. Pan D, Pesola JM, Li G, McCarron S, Coen DM. Mutations Inactivating Herpes Simplex Virus 1 MicroRNA miR-H2 Do Not Detectably Increase ICP0 Gene Expression in Infected Cultured Cells or Mouse Trigeminal Ganglia. J Virol. 2017 Jan 15; 91(2). PMID: 27847363.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  8. Chen H, Coseno M, Ficarro SB, Mansueto MS, Komazin-Meredith G, Boissel S, Filman DJ, Marto JA, Hogle JM, Coen DM. A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions. ACS Infect Dis. 2017 02 10; 3(2):112-118. PMID: 28183184.
    Citations:    Fields:    Translation:HumansCells
  9. Polachek WS, Moshrif HF, Franti M, Coen DM, Sreenu VB, Strang BL. High-Throughput Small Interfering RNA Screening Identifies Phosphatidylinositol 3-Kinase Class II Alpha as Important for Production of Human Cytomegalovirus Virions. J Virol. 2016 09 15; 90(18):8360-71. PMID: 27412598.
    Citations: 5     Fields:    Translation:HumansCells
  10. Wilkie AR, Lawler JL, Coen DM. A Role for Nuclear F-Actin Induction in Human Cytomegalovirus Nuclear Egress. MBio. 2016 08 23; 7(4). PMID: 27555312; PMCID: PMC4999551.
    Citations: 6     Fields:    Translation:HumansCells
  11. Rosato PC, Katzenell S, Pesola JM, North B, Coen DM, Leib DA. Neuronal IFN signaling is dispensable for the establishment of HSV-1 latency. Virology. 2016 10; 497:323-327. PMID: 27518540; PMCID: PMC5026629.
    Citations: 1     Fields:    Translation:AnimalsCells
  12. Chen H, Li C, Zemlicka J, Gentry BG, Bowlin TL, Coen DM. Potency and Stereoselectivity of Cyclopropavir Triphosphate Action on Human Cytomegalovirus DNA Polymerase. Antimicrob Agents Chemother. 2016 07; 60(7):4176-82. PMID: 27139481; PMCID: PMC4914631.
    Citations:    Fields:    Translation:Cells
  13. Raja P, Lee JS, Pan D, Pesola JM, Coen DM, Knipe DM. A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin. MBio. 2016 05 17; 7(3). PMID: 27190217; PMCID: PMC4895110.
    Citations: 10     Fields:    Translation:AnimalsCells
  14. Colgrove RC, Liu X, Griffiths A, Raja P, Deluca NA, Newman RM, Coen DM, Knipe DM. History and genomic sequence analysis of the herpes simplex virus 1 KOS and KOS1.1 sub-strains. Virology. 2016 Jan; 487:215-21. PMID: 26547038.
    Citations: 6     Fields:    Translation:AnimalsCells
  15. Lye MF, Sharma M, El Omari K, Filman DJ, Schuermann JP, Hogle JM, Coen DM. Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex. EMBO J. 2015 Dec 02; 34(23):2937-52. PMID: 26511021; PMCID: PMC4687685.
    Citations: 15     Fields:    Translation:Cells
  16. Sharma M, Kamil JP, Coen DM. Preparation of the Human Cytomegalovirus Nuclear Egress Complex and Associated Proteins. Methods Enzymol. 2016; 569:517-26. PMID: 26778574.
    Citations: 3     Fields:    Translation:HumansCells
  17. Leigh KE, Sharma M, Mansueto MS, Boeszoermenyi A, Filman DJ, Hogle JM, Wagner G, Coen DM, Arthanari H. Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):9010-5. PMID: 26150520; PMCID: PMC4517201.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  18. Chen H, Beardsley GP, Coen DM. Mechanism of ganciclovir-induced chain termination revealed by resistant viral polymerase mutants with reduced exonuclease activity. Proc Natl Acad Sci U S A. 2014 Dec 09; 111(49):17462-7. PMID: 25422422; PMCID: PMC4267342.
    Citations: 7     Fields:    Translation:Cells
  19. Sharma M, Bender BJ, Kamil JP, Lye MF, Pesola JM, Reim NI, Hogle JM, Coen DM. Human cytomegalovirus UL97 phosphorylates the viral nuclear egress complex. J Virol. 2015 Jan; 89(1):523-34. PMID: 25339763; PMCID: PMC4301116.
    Citations: 10     Fields:    Translation:HumansCells
  20. Bender BJ, Coen DM, Strang BL. Dynamic and nucleolin-dependent localization of human cytomegalovirus UL84 to the periphery of viral replication compartments and nucleoli. J Virol. 2014 Oct; 88(20):11738-47. PMID: 25078694; PMCID: PMC4178712.
    Citations: 9     Fields:    Translation:HumansCells
  21. Yan Z, Bryant KF, Gregory SM, Angelova M, Dreyfus DH, Zhao XZ, Coen DM, Burke TR, Knipe DM. HIV integrase inhibitors block replication of alpha-, beta-, and gammaherpesviruses. MBio. 2014 Jul 01; 5(4):e01318-14. PMID: 24987091; PMCID: PMC4161245.
    Citations: 8     Fields:    Translation:HumansCells
  22. Sharma M, Coen DM. Comparison of effects of inhibitors of viral and cellular protein kinases on human cytomegalovirus disruption of nuclear lamina and nuclear egress. J Virol. 2014 Sep; 88(18):10982-5. PMID: 24965476; PMCID: PMC4178862.
    Citations: 7     Fields:    Translation:HumansCells
  23. Pan D, Flores O, Umbach JL, Pesola JM, Bentley P, Rosato PC, Leib DA, Cullen BR, Coen DM. A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency. Cell Host Microbe. 2014 Apr 09; 15(4):446-56. PMID: 24721573; PMCID: PMC4142646.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  24. Terrell SL, Pesola JM, Coen DM. Roles of conserved residues within the pre-NH2-terminal domain of herpes simplex virus 1 DNA polymerase in replication and latency in mice. J Gen Virol. 2014 Apr; 95(Pt 4):940-7. PMID: 24413420; PMCID: PMC3973481.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  25. Jurak I, Hackenberg M, Kim JY, Pesola JM, Everett RD, Preston CM, Wilson AC, Coen DM. Expression of herpes simplex virus 1 microRNAs in cell culture models of quiescent and latent infection. J Virol. 2014 Feb; 88(4):2337-9. PMID: 24307587; PMCID: PMC3911564.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  26. Sharma M, Kamil JP, Coughlin M, Reim NI, Coen DM. Human cytomegalovirus UL50 and UL53 recruit viral protein kinase UL97, not protein kinase C, for disruption of nuclear lamina and nuclear egress in infected cells. J Virol. 2014 Jan; 88(1):249-62. PMID: 24155370; PMCID: PMC3911691.
    Citations: 28     Fields:    Translation:HumansCells
  27. Pan D, Kaye SB, Hopkins M, Kirwan R, Hart IJ, Coen DM. Common and new acyclovir resistant herpes simplex virus-1 mutants causing bilateral recurrent herpetic keratitis in an immunocompetent patient. J Infect Dis. 2014 Feb 01; 209(3):345-9. PMID: 23945375; PMCID: PMC3883165.
    Citations: 3     Fields:    Translation:HumansCells
  28. Reim NI, Kamil JP, Wang D, Lin A, Sharma M, Ericsson M, Pesola JM, Golan DE, Coen DM. Inactivation of retinoblastoma protein does not overcome the requirement for human cytomegalovirus UL97 in lamina disruption and nuclear egress. J Virol. 2013 May; 87(9):5019-27. PMID: 23427156; PMCID: PMC3624322.
    Citations: 13     Fields:    Translation:HumansCells
  29. Cliffe AR, Coen DM, Knipe DM. Kinetics of facultative heterochromatin and polycomb group protein association with the herpes simplex viral genome during establishment of latent infection. MBio. 2013 Jan 15; 4(1). PMID: 23322639; PMCID: PMC3551550.
    Citations: 28     Fields:    Translation:AnimalsCells
  30. Weller SK, Coen DM. Herpes simplex viruses: mechanisms of DNA replication. Cold Spring Harb Perspect Biol. 2012 Sep 01; 4(9):a013011. PMID: 22952399; PMCID: PMC3428768.
    Citations: 48     Fields:    Translation:Cells
  31. Pan D, Coen DM. Net -1 frameshifting on a noncanonical sequence in a herpes simplex virus drug-resistant mutant is stimulated by nonstop mRNA. Proc Natl Acad Sci U S A. 2012 Sep 11; 109(37):14852-7. PMID: 22927407; PMCID: PMC3443137.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  32. Terrell SL, Coen DM. The pre-NH(2)-terminal domain of the herpes simplex virus 1 DNA polymerase catalytic subunit is required for efficient viral replication. J Virol. 2012 Oct; 86(20):11057-65. PMID: 22875965; PMCID: PMC3457154.
    Citations: 6     Fields:    Translation:AnimalsCells
  33. Strang BL, Bender BJ, Sharma M, Pesola JM, Sanders RL, Spector DH, Coen DM. A mutation deleting sequences encoding the amino terminus of human cytomegalovirus UL84 impairs interaction with UL44 and capsid localization. J Virol. 2012 Oct; 86(20):11066-77. PMID: 22855486; PMCID: PMC3457161.
    Citations: 12     Fields:    Translation:HumansCells
  34. Jurak I, Silverstein LB, Sharma M, Coen DM. Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity. J Virol. 2012 Sep; 86(18):10093-102. PMID: 22787211; PMCID: PMC3446562.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  35. Strang BL, Boulant S, Kirchhausen T, Coen DM. Host cell nucleolin is required to maintain the architecture of human cytomegalovirus replication compartments. MBio. 2012; 3(1). PMID: 22318319; PMCID: PMC3280463.
    Citations: 16     Fields:    Translation:HumansCells
  36. Pan D, Coen DM. Quantification and analysis of thymidine kinase expression from acyclovir-resistant G-string insertion and deletion mutants in herpes simplex virus-infected cells. J Virol. 2012 Apr; 86(8):4518-26. PMID: 22301158; PMCID: PMC3318614.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  37. Strang BL, Boulant S, Chang L, Knipe DM, Kirchhausen T, Coen DM. Human cytomegalovirus UL44 concentrates at the periphery of replication compartments, the site of viral DNA synthesis. J Virol. 2012 Feb; 86(4):2089-95. PMID: 22156516; PMCID: PMC3302373.
    Citations: 17     Fields:    Translation:HumansCells
  38. Coen DM, Whitley RJ. Antiviral drugs and antiviral drug resistance. Curr Opin Virol. 2011 Dec; 1(6):545-7. PMID: 22440912; PMCID: PMC3433155.
    Citations: 2     Fields:    Translation:Humans
  39. Kramer MF, Jurak I, Pesola JM, Boissel S, Knipe DM, Coen DM. Herpes simplex virus 1 microRNAs expressed abundantly during latent infection are not essential for latency in mouse trigeminal ganglia. Virology. 2011 Sep 01; 417(2):239-47. PMID: 21782205; PMCID: PMC3572766.
    Citations: 25     Fields:    Translation:AnimalsCells
  40. Silva LA, Strang BL, Lin EW, Kamil JP, Coen DM. Sites and roles of phosphorylation of the human cytomegalovirus DNA polymerase subunit UL44. Virology. 2011 Sep 01; 417(2):268-80. PMID: 21784501; PMCID: PMC3434964.
    Citations: 8     Fields:    Translation:HumansCells
  41. Jurak I, Griffiths A, Coen DM. Mammalian alphaherpesvirus miRNAs. Biochim Biophys Acta. 2011 Nov-Dec; 1809(11-12):641-53. PMID: 21736960; PMCID: PMC3382970.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  42. Kamil JP, Coen DM. HATs on for drug resistance. Cell Host Microbe. 2011 Feb 17; 9(2):85-7. PMID: 21320689; PMCID: PMC3072411.
    Citations: 1     Fields:    
  43. Silva LA, Loregian A, Pari GS, Strang BL, Coen DM. The carboxy-terminal segment of the human cytomegalovirus DNA polymerase accessory subunit UL44 is crucial for viral replication. J Virol. 2010 Nov; 84(21):11563-8. PMID: 20739543; PMCID: PMC2953201.
    Citations: 5     Fields:    Translation:HumansCells
  44. Tran K, Kamil JP, Coen DM, Spector DH. Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1. J Virol. 2010 Oct; 84(20):10832-43. PMID: 20686030; PMCID: PMC2950577.
    Citations: 17     Fields:    Translation:HumansCells
  45. Gentry BG, Kamil JP, Coen DM, Zemlicka J, Drach JC. Stereoselective phosphorylation of cyclopropavir by pUL97 and competitive inhibition by maribavir. Antimicrob Agents Chemother. 2010 Aug; 54(8):3093-8. PMID: 20547817; PMCID: PMC2916337.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  46. Strang BL, Geballe AP, Coen DM. Association of human cytomegalovirus proteins IRS1 and TRS1 with the viral DNA polymerase accessory subunit UL44. J Gen Virol. 2010 Sep; 91(Pt 9):2167-75. PMID: 20444996; PMCID: PMC3052514.
    Citations: 23     Fields:    Translation:HumansCells
  47. Coen D. Priscilla Schaffer (1941-2009): a stalwart herpesvirologist. J Virol. 2010 Jul; 84(13):6265-7. PMID: 20427529; PMCID: PMC2903263.
    Citations:    Fields:    Translation:HumansCells
  48. Strang BL, Coen DM. Interaction of the human cytomegalovirus uracil DNA glycosylase UL114 with the viral DNA polymerase catalytic subunit UL54. J Gen Virol. 2010 Aug; 91(Pt 8):2029-33. PMID: 20410316; PMCID: PMC3052538.
    Citations: 8     Fields:    Translation:HumansCells
  49. Jurak I, Kramer MF, Mellor JC, van Lint AL, Roth FP, Knipe DM, Coen DM. Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2. J Virol. 2010 May; 84(9):4659-72. PMID: 20181707; PMCID: PMC2863732.
    Citations: 60     Fields:    Translation:HumansAnimalsCells
  50. Strang BL, Boulant S, Coen DM. Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication. J Virol. 2010 Feb; 84(4):1771-84. PMID: 20007282; PMCID: PMC2812382.
    Citations: 32     Fields:    Translation:HumansCells
  51. Baltz JL, Filman DJ, Ciustea M, Silverman JE, Lautenschlager CL, Coen DM, Ricciardi RP, Hogle JM. The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus. J Virol. 2009 Dec; 83(23):12215-28. PMID: 19759157.
    Citations: 4     Fields:    Translation:HumansCells
  52. Kamil JP, Hume AJ, Jurak I, Münger K, Kalejta RF, Coen DM. Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase. Proc Natl Acad Sci U S A. 2009 Sep 29; 106(39):16823-8. PMID: 19805380; PMCID: PMC2757844.
    Citations: 26     Fields:    Translation:HumansCells
  53. Jiang C, Komazin-Meredith G, Tian W, Coen DM, Hwang CB. Mutations that increase DNA binding by the processivity factor of herpes simplex virus affect virus production and DNA replication fidelity. J Virol. 2009 Aug; 83(15):7573-80. PMID: 19474109; PMCID: PMC2708624.
    Citations: 6     Fields:    Translation:AnimalsCells
  54. Strang BL, Sinigalia E, Silva LA, Coen DM, Loregian A. Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84. J Virol. 2009 Aug; 83(15):7581-9. PMID: 19457994; PMCID: PMC2708651.
    Citations: 21     Fields:    Translation:HumansCells
  55. Hamirally S, Kamil JP, Ndassa-Colday YM, Lin AJ, Jahng WJ, Baek MC, Noton S, Silva LA, Simpson-Holley M, Knipe DM, Golan DE, Marto JA, Coen DM. Viral mimicry of Cdc2/cyclin-dependent kinase 1 mediates disruption of nuclear lamina during human cytomegalovirus nuclear egress. PLoS Pathog. 2009 Jan; 5(1):e1000275. PMID: 19165338; PMCID: PMC2625439.
    Citations: 83     Fields:    Translation:HumansCells
  56. Sam MD, Evans BT, Coen DM, Hogle JM. Biochemical, biophysical, and mutational analyses of subunit interactions of the human cytomegalovirus nuclear egress complex. J Virol. 2009 Apr; 83(7):2996-3006. PMID: 19153235; PMCID: PMC2655548.
    Citations: 22     Fields:    Translation:HumansCells
  57. Sinigalia E, Alvisi G, Mercorelli B, Coen DM, Pari GS, Jans DA, Ripalti A, Palù G, Loregian A. Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells. J Virol. 2008 Dec; 82(24):12574-9. PMID: 18842734; PMCID: PMC2593364.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  58. Bryant KF, Macari ER, Malik N, Boyce M, Yuan J, Coen DM. ICP34.5-dependent and -independent activities of salubrinal in herpes simplex virus-1 infected cells. Virology. 2008 Sep 30; 379(2):197-204. PMID: 18684481; PMCID: PMC2665023.
    Citations: 9     Fields:    Translation:AnimalsCells
  59. Komazin-Meredith G, Petrella RJ, Santos WL, Filman DJ, Hogle JM, Verdine GL, Karplus M, Coen DM. The human cytomegalovirus UL44 C clamp wraps around DNA. Structure. 2008 Aug 06; 16(8):1214-25. PMID: 18682223; PMCID: PMC2878485.
    Citations: 11     Fields:    Translation:HumansCells
  60. Komazin-Meredith G, Mirchev R, Golan DE, van Oijen AM, Coen DM. Hopping of a processivity factor on DNA revealed by single-molecule assays of diffusion. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):10721-6. PMID: 18658237; PMCID: PMC2504831.
    Citations: 26     Fields:    Translation:Cells
  61. Umbach JL, Kramer MF, Jurak I, Karnowski HW, Coen DM, Cullen BR. MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs. Nature. 2008 Aug 07; 454(7205):780-3. PMID: 18596690; PMCID: PMC2666538.
    Citations: 287     Fields:    Translation:HumansAnimalsCells
  62. Hume AJ, Finkel JS, Kamil JP, Coen DM, Culbertson MR, Kalejta RF. Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function. Science. 2008 May 09; 320(5877):797-9. PMID: 18467589.
    Citations: 92     Fields:    Translation:HumansCells
  63. Komazin-Meredith G, Santos WL, Filman DJ, Hogle JM, Verdine GL, Coen DM. The positively charged surface of herpes simplex virus UL42 mediates DNA binding. J Biol Chem. 2008 Mar 07; 283(10):6154-61. PMID: 18178550; PMCID: PMC2889492.
    Citations: 12     Fields:    Translation:Cells
  64. Bryant KF, Coen DM. Inhibition of translation by a short element in the 5' leader of the herpes simplex virus 1 DNA polymerase transcript. J Virol. 2008 Jan; 82(1):77-85. PMID: 17959669; PMCID: PMC2224361.
    Citations: 1     Fields:    Translation:AnimalsCells
  65. Jiang C, Hwang YT, Wang G, Randell JC, Coen DM, Hwang CB. Herpes simplex virus mutants with multiple substitutions affecting DNA binding of UL42 are impaired for viral replication and DNA synthesis. J Virol. 2007 Nov; 81(21):12077-9. PMID: 17715219; PMCID: PMC2168780.
    Citations: 7     Fields:    Translation:AnimalsCells
  66. Kamil JP, Coen DM. Human cytomegalovirus protein kinase UL97 forms a complex with the tegument phosphoprotein pp65. J Virol. 2007 Oct; 81(19):10659-68. PMID: 17634236; PMCID: PMC2045453.
    Citations: 44     Fields:    Translation:HumansCells
  67. Loregian A, Sinigalia E, Mercorelli B, Palù G, Coen DM. Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism. Nucleic Acids Res. 2007; 35(14):4779-91. PMID: 17617644; PMCID: PMC1950537.
    Citations: 11     Fields:    Translation:Cells
  68. Dodson AW, Taylor TJ, Knipe DM, Coen DM. Inhibitors of the sodium potassium ATPase that impair herpes simplex virus replication identified via a chemical screening approach. Virology. 2007 Sep 30; 366(2):340-8. PMID: 17544048; PMCID: PMC2099250.
    Citations: 14     Fields:    Translation:AnimalsCells
  69. Besecker MI, Furness CL, Coen DM, Griffiths A. Expression of extremely low levels of thymidine kinase from an acyclovir-resistant herpes simplex virus mutant supports reactivation from latently infected mouse trigeminal ganglia. J Virol. 2007 Aug; 81(15):8356-60. PMID: 17522225; PMCID: PMC1951311.
    Citations: 5     Fields:    Translation:AnimalsCells
  70. Pesola JM, Coen DM. In vivo fitness and virulence of a drug-resistant herpes simplex virus 1 mutant. J Gen Virol. 2007 May; 88(Pt 5):1410-4. PMID: 17412967.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  71. Jiang C, Hwang YT, Randell JC, Coen DM, Hwang CB. Mutations that decrease DNA binding of the processivity factor of the herpes simplex virus DNA polymerase reduce viral yield, alter the kinetics of viral DNA replication, and decrease the fidelity of DNA replication. J Virol. 2007 Apr; 81(7):3495-502. PMID: 17229696; PMCID: PMC1866068.
    Citations: 10     Fields:    Translation:AnimalsCells
  72. Kramer MF, Coen DM. Enzymatic amplification of DNA by PCR: standard procedures and optimization. Curr Protoc Cytom. 2006 Aug; Appendix 3:Appendix 3K. PMID: 18770830.
    Citations: 2     Fields:    Translation:Cells
  73. Griffiths A, Link MA, Furness CL, Coen DM. Low-level expression and reversion both contribute to reactivation of herpes simplex virus drug-resistant mutants with mutations on homopolymeric sequences in thymidine kinase. J Virol. 2006 Jul; 80(13):6568-74. PMID: 16775343; PMCID: PMC1488940.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  74. Cui C, Griffiths A, Li G, Silva LM, Kramer MF, Gaasterland T, Wang XJ, Coen DM. Prediction and identification of herpes simplex virus 1-encoded microRNAs. J Virol. 2006 Jun; 80(11):5499-508. PMID: 16699030; PMCID: PMC1472173.
    Citations: 98     Fields:    Translation:AnimalsCells
  75. Shogan B, Kruse L, Mulamba GB, Hu A, Coen DM. Virucidal activity of a GT-rich oligonucleotide against herpes simplex virus mediated by glycoprotein B. J Virol. 2006 May; 80(10):4740-7. PMID: 16641267; PMCID: PMC1472053.
    Citations: 12     Fields:    Translation:AnimalsCells
  76. Loregian A, Coen DM. Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase. Chem Biol. 2006 Feb; 13(2):191-200. PMID: 16492567.
    Citations: 20     Fields:    Translation:HumansCells
  77. Appleton BA, Brooks J, Loregian A, Filman DJ, Coen DM, Hogle JM. Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44. J Biol Chem. 2006 Feb 24; 281(8):5224-32. PMID: 16371349.
    Citations: 21     Fields:    Translation:HumansCells
  78. Pesola JM, Zhu J, Knipe DM, Coen DM. Herpes simplex virus 1 immediate-early and early gene expression during reactivation from latency under conditions that prevent infectious virus production. J Virol. 2005 Dec; 79(23):14516-25. PMID: 16282451; PMCID: PMC1287588.
    Citations: 38     Fields:    Translation:AnimalsCells
  79. Wang QY, Zhou C, Johnson KE, Colgrove RC, Coen DM, Knipe DM. Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection. Proc Natl Acad Sci U S A. 2005 Nov 01; 102(44):16055-9. PMID: 16247011; PMCID: PMC1266038.
    Citations: 120     Fields:    Translation:AnimalsCells
  80. Bryant KF, Cox JC, Wang H, Hogle JM, Ellington AD, Coen DM. Binding of herpes simplex virus-1 US11 to specific RNA sequences. Nucleic Acids Res. 2005; 33(19):6090-100. PMID: 16246910; PMCID: PMC1266072.
    Citations: 10     Fields:    Translation:Cells
  81. Randell JC, Komazin G, Jiang C, Hwang CB, Coen DM. Effects of substitutions of arginine residues on the basic surface of herpes simplex virus UL42 support a role for DNA binding in processive DNA synthesis. J Virol. 2005 Sep; 79(18):12025-34. PMID: 16140778; PMCID: PMC1212618.
    Citations: 13     Fields:    Translation:Cells
  82. Griffiths A, Coen DM. An unusual internal ribosome entry site in the herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci U S A. 2005 Jul 05; 102(27):9667-72. PMID: 15972803; PMCID: PMC1172279.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  83. Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, Kaufman RJ, Ma D, Coen DM, Ron D, Yuan J. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science. 2005 Feb 11; 307(5711):935-9. PMID: 15705855.
    Citations: 448     Fields:    Translation:AnimalsCells
  84. Cook WJ, Kramer MF, Walker RM, Burwell TJ, Holman HA, Coen DM, Knipe DM. Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection. Virol J. 2004 Sep 23; 1:5. PMID: 15507126; PMCID: PMC524517.
    Citations: 24     Fields:    Translation:AnimalsCells
  85. Loregian A, Appleton BA, Hogle JM, Coen DM. Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit. J Virol. 2004 Sep; 78(17):9084-92. PMID: 15308704; PMCID: PMC506919.
    Citations: 23     Fields:    Translation:HumansCells
  86. Appleton BA, Loregian A, Filman DJ, Coen DM, Hogle JM. The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer. Mol Cell. 2004 Jul 23; 15(2):233-44. PMID: 15260974.
    Citations: 38     Fields:    Translation:HumansCells
  87. Baek MC, Krosky PM, Pearson A, Coen DM. Phosphorylation of the RNA polymerase II carboxyl-terminal domain in human cytomegalovirus-infected cells and in vitro by the viral UL97 protein kinase. Virology. 2004 Jun 20; 324(1):184-93. PMID: 15183065.
    Citations: 28     Fields:    Translation:HumansCells
  88. Pilger BD, Cui C, Coen DM. Identification of a small molecule that inhibits herpes simplex virus DNA Polymerase subunit interactions and viral replication. Chem Biol. 2004 May; 11(5):647-54. PMID: 15157875.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  89. Randell JC, Coen DM. The herpes simplex virus processivity factor, UL42, binds DNA as a monomer. J Mol Biol. 2004 Jan 09; 335(2):409-13. PMID: 14672651.
    Citations: 20     Fields:    Translation:HumansCells
  90. Loregian A, Appleton BA, Hogle JM, Coen DM. Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44. J Virol. 2004 Jan; 78(1):158-67. PMID: 14671097; PMCID: PMC303418.
    Citations: 24     Fields:    Translation:HumansCells
  91. Pearson A, Knipe DM, Coen DM. ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells. J Virol. 2004 Jan; 78(1):23-32. PMID: 14671084; PMCID: PMC303382.
    Citations: 11     Fields:    Translation:AnimalsCells
  92. Chen SH, Pearson A, Coen DM, Chen SH. Failure of thymidine kinase-negative herpes simplex virus to reactivate from latency following efficient establishment. J Virol. 2004 Jan; 78(1):520-3. PMID: 14671133; PMCID: PMC303395.
    Citations: 13     Fields:    Translation:AnimalsCells
  93. Kramer MF, Cook WJ, Roth FP, Zhu J, Holman H, Knipe DM, Coen DM. Latent herpes simplex virus infection of sensory neurons alters neuronal gene expression. J Virol. 2003 Sep; 77(17):9533-41. PMID: 12915567; PMCID: PMC187408.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  94. Krosky PM, Baek MC, Jahng WJ, Barrera I, Harvey RJ, Biron KK, Coen DM, Sethna PB. The human cytomegalovirus UL44 protein is a substrate for the UL97 protein kinase. J Virol. 2003 Jul; 77(14):7720-7. PMID: 12829811; PMCID: PMC161957.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  95. Coen DM, Schaffer PA. Antiherpesvirus drugs: a promising spectrum of new drugs and drug targets. Nat Rev Drug Discov. 2003 Apr; 2(4):278-88. PMID: 12669027.
    Citations: 29     Fields:    Translation:HumansCells
  96. Griffiths A, Chen SH, Horsburgh BC, Coen DM. Translational compensation of a frameshift mutation affecting herpes simplex virus thymidine kinase is sufficient to permit reactivation from latency. J Virol. 2003 Apr; 77(8):4703-9. PMID: 12663777; PMCID: PMC152167.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  97. Kramer M, Riley J, Spoering A, Coen D, Knipe D. Effect of immunization on herpes simplex virus type 1 latent infection in the trigeminal ganglion. Curr Eye Res. 2003 Mar-Apr; 26(3-4):185-94. PMID: 12815546.
    Citations:    Fields:    Translation:AnimalsCellsPHPublic Health
  98. Griffiths A, Coen DM. High-frequency phenotypic reversion and pathogenicity of an acyclovir-resistant herpes simplex virus mutant. J Virol. 2003 Feb; 77(3):2282-6. PMID: 12525666; PMCID: PMC140925.
    Citations: 14     Fields:    Translation:AnimalsCells
  99. Krosky PM, Baek MC, Coen DM. The human cytomegalovirus UL97 protein kinase, an antiviral drug target, is required at the stage of nuclear egress. J Virol. 2003 Jan; 77(2):905-14. PMID: 12502806; PMCID: PMC140798.
    Citations: 88     Fields:    Translation:Cells
  100. Baek MC, Krosky PM, Coen DM. Relationship between autophosphorylation and phosphorylation of exogenous substrates by the human cytomegalovirus UL97 protein kinase. J Virol. 2002 Dec; 76(23):11943-52. PMID: 12414936; PMCID: PMC136897.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  101. Pearson A, Coen DM. Identification, localization, and regulation of expression of the UL24 protein of herpes simplex virus type 1. J Virol. 2002 Nov; 76(21):10821-8. PMID: 12368325; PMCID: PMC136619.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  102. Kramer MF, Coen DM. The polymerase chain reaction. Curr Protoc Protein Sci. 2002 Nov; Appendix 4:Appendix 4J. PMID: 18429219.
    Citations: 1     Fields:    Translation:Animals
  103. Baek MC, Krosky PM, He Z, Coen DM. Specific phosphorylation of exogenous protein and peptide substrates by the human cytomegalovirus UL97 protein kinase. Importance of the P+5 position. J Biol Chem. 2002 Aug 16; 277(33):29593-9. PMID: 12048183.
    Citations: 27     Fields:    Translation:AnimalsCells
  104. Chen SH, Lee LY, Garber DA, Schaffer PA, Knipe DM, Coen DM. Neither LAT nor open reading frame P mutations increase expression of spliced or intron-containing ICP0 transcripts in mouse ganglia latently infected with herpes simplex virus. J Virol. 2002 May; 76(10):4764-72. PMID: 11967293; PMCID: PMC136172.
    Citations: 32     Fields:    Translation:AnimalsCells
  105. Coen DM. Quantitation of rare DNAs by PCR. Curr Protoc Mol Biol. 2001 Nov; Chapter 15:Unit 15.7. PMID: 18265121.
    Citations:    Fields:    
  106. Kramer MF, Coen DM. Enzymatic amplification of DNA by PCR: standard procedures and optimization. Curr Protoc Mol Biol. 2001 Nov; Chapter 15:Unit 15.1. PMID: 18265115.
    Citations: 9     Fields:    Translation:Animals
  107. Randell JC, Coen DM. Linear diffusion on DNA despite high-affinity binding by a DNA polymerase processivity factor. Mol Cell. 2001 Oct; 8(4):911-20. PMID: 11684025.
    Citations: 13     Fields:    Translation:Cells
  108. Kramer MF, Coen DM. Enzymatic amplification of DNA by PCR: standard procedures and optimization. Curr Protoc Pharmacol. 2001 Aug; Chapter 6:Unit6.7. PMID: 21959762.
    Citations:    Fields:    
  109. Bridges KG, Chow CS, Coen DM. Identification of crucial hydrogen-bonding residues for the interaction of herpes simplex virus DNA polymerase subunits via peptide display, mutational, and calorimetric approaches. J Virol. 2001 Jun; 75(11):4990-8. PMID: 11333878; PMCID: PMC114902.
    Citations: 8     Fields:    Translation:Cells
  110. Kramer MF, Coen DM. Enzymatic amplification of DNA by PCR: standard procedures and optimization. Curr Protoc Toxicol. 2001 May; Appendix 3:A.3C.1-14. PMID: 20972963.
    Citations: 3     Fields:    
  111. Coen DM. Quantitation of rare DNAs by PCR. Curr Protoc Immunol. 2001 May; Chapter 10:Unit 10.21. PMID: 18432686.
    Citations:    Fields:    
  112. Kramer MF, Coen DM. Enzymatic amplification of DNA by PCR: standard procedures and optimization. Curr Protoc Cell Biol. 2001 May; Appendix 3:Appendix 3F. PMID: 18228288.
    Citations: 1     Fields:    Translation:HumansAnimals
  113. Kramer MF, Coen DM. Enzymatic amplification of DNA by PCR: standard procedures and optimization. Curr Protoc Immunol. 2001 May; Chapter 10:Unit 10.20. PMID: 18432685.
    Citations: 3     Fields:    
  114. Burkham J, Coen DM, Hwang CB, Weller SK. Interactions of herpes simplex virus type 1 with ND10 and recruitment of PML to replication compartments. J Virol. 2001 Mar; 75(5):2353-67. PMID: 11160739; PMCID: PMC114819.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  115. Chen SH, Garber DA, Schaffer PA, Knipe DM, Coen DM. Persistent elevated expression of cytokine transcripts in ganglia latently infected with herpes simplex virus in the absence of ganglionic replication or reactivation. Virology. 2000 Dec 05; 278(1):207-16. PMID: 11112495.
    Citations: 32     Fields:    Translation:AnimalsCells
  116. Zuccola HJ, Filman DJ, Coen DM, Hogle JM. The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase. Mol Cell. 2000 Feb; 5(2):267-78. PMID: 10882068.
    Citations: 56     Fields:    Translation:Cells
  117. Bridges KG, Hua Q, Brigham-Burke MR, Martin JD, Hensley P, Dahl CE, Digard P, Weiss MA, Coen DM. Secondary structure and structure-activity relationships of peptides corresponding to the subunit interface of herpes simplex virus DNA polymerase. J Biol Chem. 2000 Jan 07; 275(1):472-8. PMID: 10617641.
    Citations: 8     Fields:    Translation:Cells
  118. Talarico CL, Burnette TC, Miller WH, Smith SL, Davis MG, Stanat SC, Ng TI, He Z, Coen DM, Roizman B, Biron KK. Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein. Antimicrob Agents Chemother. 1999 Aug; 43(8):1941-6. PMID: 10428917; PMCID: PMC89395.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  119. Prichard MN, Gao N, Jairath S, Mulamba G, Krosky P, Coen DM, Parker BO, Pari GS. A recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency. J Virol. 1999 Jul; 73(7):5663-70. PMID: 10364316; PMCID: PMC112625.
    Citations: 88     Fields:    Translation:HumansAnimalsCells
  120. Huang L, Ishii KK, Zuccola H, Gehring AM, Hwang CB, Hogle J, Coen DM. The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerases. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):447-52. PMID: 9892653; PMCID: PMC15156.
    Citations: 13     Fields:    Translation:Cells
  121. Weisshart K, Chow CS, Coen DM. Herpes simplex virus processivity factor UL42 imparts increased DNA-binding specificity to the viral DNA polymerase and decreased dissociation from primer-template without reducing the elongation rate. J Virol. 1999 Jan; 73(1):55-66. PMID: 9847307; PMCID: PMC103808.
    Citations: 23     Fields:    Translation:Cells
  122. Pelosi E, Rozenberg F, Coen DM, Tyler KL. A herpes simplex virus DNA polymerase mutation that specifically attenuates neurovirulence in mice. Virology. 1998 Dec 20; 252(2):364-72. PMID: 9878615.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  123. Burkham J, Coen DM, Weller SK. ND10 protein PML is recruited to herpes simplex virus type 1 prereplicative sites and replication compartments in the presence of viral DNA polymerase. J Virol. 1998 Dec; 72(12):10100-7. PMID: 9811750; PMCID: PMC110544.
    Citations: 58     Fields:    Translation:HumansCells
  124. Hann LE, Cook WJ, Uprichard SL, Knipe DM, Coen DM. The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylation. J Virol. 1998 Oct; 72(10):7709-14. PMID: 9733806; PMCID: PMC110073.
    Citations: 19     Fields:    Translation:AnimalsCells
  125. Horsburgh BC, Chen SH, Hu A, Mulamba GB, Burns WH, Coen DM. Recurrent acyclovir-resistant herpes simplex in an immunocompromised patient: can strain differences compensate for loss of thymidine kinase in pathogenesis? J Infect Dis. 1998 Sep; 178(3):618-25. PMID: 9728528.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  126. Chen SH, Cook WJ, Grove KL, Coen DM. Human thymidine kinase can functionally replace herpes simplex virus type 1 thymidine kinase for viral replication in mouse sensory ganglia and reactivation from latency upon explant. J Virol. 1998 Aug; 72(8):6710-5. PMID: 9658118; PMCID: PMC109874.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  127. Netter S, Fauvarque MO, Diez del Corral R, Dura JM, Coen D. white+ transgene insertions presenting a dorsal/ventral pattern define a single cluster of homeobox genes that is silenced by the polycomb-group proteins in Drosophila melanogaster. Genetics. 1998 May; 149(1):257-75. PMID: 9584101; PMCID: PMC1460120.
    Citations: 13     Fields:    Translation:AnimalsCells
  128. Coen DM. The persistence of (HIV in) memory (T cells). Trends Microbiol. 1998 Apr; 6(4):129-30. PMID: 9587186.
    Citations:    Fields:    Translation:HumansCells
  129. Mulamba GB, Hu A, Azad RF, Anderson KP, Coen DM. Human cytomegalovirus mutant with sequence-dependent resistance to the phosphorothioate oligonucleotide fomivirsen (ISIS 2922). Antimicrob Agents Chemother. 1998 Apr; 42(4):971-3. PMID: 9559825; PMCID: PMC105584.
    Citations: 14     Fields:    Translation:HumansCells
  130. Jacobson JG, Chen SH, Cook WJ, Kramer MF, Coen DM. Importance of the herpes simplex virus UL24 gene for productive ganglionic infection in mice. Virology. 1998 Mar 01; 242(1):161-9. PMID: 9501052.
    Citations: 35     Fields:    Translation:AnimalsCells
  131. Kramer MF, Chen SH, Knipe DM, Coen DM. Accumulation of viral transcripts and DNA during establishment of latency by herpes simplex virus. J Virol. 1998 Feb; 72(2):1177-85. PMID: 9445016.
    Citations: 45     Fields:    Translation:AnimalsCells
  132. Pelosi E, Mulamba GB, Coen DM. Penciclovir and pathogenesis phenotypes of drug-resistant Herpes simplex virus mutants. Antiviral Res. 1998 Jan; 37(1):17-28. PMID: 9497069.
    Citations: 11     Fields:    Translation:AnimalsCells
  133. Hwang YT, Liu BY, Coen DM, Hwang CB. Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity. J Virol. 1997 Oct; 71(10):7791-8. PMID: 9311864; PMCID: PMC192131.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  134. Chen SH, Kramer MF, Schaffer PA, Coen DM. A viral function represses accumulation of transcripts from productive-cycle genes in mouse ganglia latently infected with herpes simplex virus. J Virol. 1997 Aug; 71(8):5878-84. PMID: 9223477; PMCID: PMC191843.
    Citations: 91     Fields:    Translation:AnimalsCells
  135. He Z, He YS, Kim Y, Chu L, Ohmstede C, Biron KK, Coen DM. The human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines. J Virol. 1997 Jan; 71(1):405-11. PMID: 8985364; PMCID: PMC191065.
    Citations: 67     Fields:    Translation:HumansAnimalsCells
  136. Horsburgh BC, Kollmus H, Hauser H, Coen DM. Translational recoding induced by G-rich mRNA sequences that form unusual structures. Cell. 1996 Sep 20; 86(6):949-59. PMID: 8808630.
    Citations: 25     Fields:    Translation:AnimalsCells
  137. Cook WJ, Coen DM. Temporal regulation of herpes simplex virus type 1 UL24 mRNA expression via differential polyadenylation. Virology. 1996 Apr 01; 218(1):204-13. PMID: 8615023.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  138. Cook WJ, Wobbe KK, Böni J, Coen DM. Regulation of neighboring gene expression by the herpes simplex virus type 1 thymidine kinase gene. Virology. 1996 Apr 01; 218(1):193-203. PMID: 8615022.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  139. Coen DM. Wheel keeps turning for antiviral combination chemotherapy. Trends Microbiol. 1996 Feb; 4(2):51-2. PMID: 8820566.
    Citations:    Fields:    
  140. Coen DM. Antiviral drug resistance in herpes simplex virus. Adv Exp Med Biol. 1996; 394:49-57. PMID: 8815709.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  141. Delattre M, Anxolabéhère D, Coen D. Prevalence of localized rearrangements vs. transpositions among events induced by Drosophila P element transposase on a P transgene. Genetics. 1995 Dec; 141(4):1407-24. PMID: 8601483; PMCID: PMC1206876.
    Citations: 11     Fields:    Translation:AnimalsCells
  142. Chow CS, Coen DM. Mutations that specifically impair the DNA binding activity of the herpes simplex virus protein UL42. J Virol. 1995 Nov; 69(11):6965-71. PMID: 7474115; PMCID: PMC189615.
    Citations: 16     Fields:    Translation:AnimalsCells
  143. Cook WJ, Lin SM, DeLuca NA, Coen DM. Initiator elements and regulated expression of the herpes simplex virus thymidine kinase gene. J Virol. 1995 Nov; 69(11):7291-4. PMID: 7474156; PMCID: PMC189656.
    Citations: 6     Fields:    Translation:AnimalsCells
  144. Cook WJ, Gu B, DeLuca NA, Moynihan EB, Coen DM. Induction of transcription by a viral regulatory protein depends on the relative strengths of functional TATA boxes. Mol Cell Biol. 1995 Sep; 15(9):4998-5006. PMID: 7651418; PMCID: