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profileAdam Goon Wai Matthews, Ph.D.

TitleResearch Fellow in Genetics (EXT)
InstitutionMassachusetts General Hospital
DepartmentGenetics
AddressMassachusetts General Hospital
Richard B. Simches Research Center - CPZN7
185 Cambridge St
Boston MA 02114
Phone617/721-2381
Fax617/726-6893
vCardDownload vCard (login for email)
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Matthews AG, Briggs CE, Yamanaka K, Small TN, Mooster JL, Bonilla FA, Oettinger MA, Butte MJ. Compound heterozygous mutation of Rag1 leading to Omenn syndrome. PLoS One. 2015; 10(4):e0121489. PMID: 25849362; PMCID: PMC4388548.
  2. Yuan CC, Matthews AG, Jin Y, Chen CF, Chapman BA, Ohsumi TK, Glass KC, Kutateladze TG, Borowsky ML, Struhl K, Oettinger MA. Histone H3R2 symmetric dimethylation and histone H3K4 trimethylation are tightly correlated in eukaryotic genomes. Cell Rep. 2012 Feb 23; 1(2):83-90. PMID: 22720264; PMCID: PMC3377377.
  3. Matthews AG, Oettinger MA. RAG: a recombinase diversified. Nat Immunol. 2009 Aug; 10(8):817-21. PMID: 19621044; PMCID: PMC3773180.
  4. Matthews AG, Oettinger MA. Regulation of RAG transposition. Adv Exp Med Biol. 2009; 650:16-31. PMID: 19731798.
    View in: PubMed
  5. Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, Gozani O, Oettinger MA. RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature. 2007 Dec 13; 450(7172):1106-10. PMID: 18033247; PMCID: PMC2988437.
  6. Ramón-Maiques S, Kuo AJ, Carney D, Matthews AG, Oettinger MA, Gozani O, Yang W. The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Proc Natl Acad Sci U S A. 2007 Nov 27; 104(48):18993-8. PMID: 18025461; PMCID: PMC2141896.
  7. Matthews AG, Elkin SK, Oettinger MA. Ordered DNA release and target capture in RAG transposition. EMBO J. 2004 Mar 10; 23(5):1198-206. PMID: 14988730; PMCID: PMC380985.
  8. Montalbano A, Ogwaro KM, Tang A, Matthews AG, Larijani M, Oettinger MA, Feeney AJ. V(D)J recombination frequencies can be profoundly affected by changes in the spacer sequence. J Immunol. 2003 Nov 15; 171(10):5296-304. PMID: 14607931.
    View in: PubMed
  9. Elkin SK, Matthews AG, Oettinger MA. The C-terminal portion of RAG2 protects against transposition in vitro. EMBO J. 2003 Apr 15; 22(8):1931-8. PMID: 12682025; PMCID: PMC154476.
  10. Mundy CL, Patenge N, Matthews AG, Oettinger MA. Assembly of the RAG1/RAG2 synaptic complex. Mol Cell Biol. 2002 Jan; 22(1):69-77. PMID: 11739723; PMCID: PMC134220.
  11. Kwon J, Imbalzano AN, Matthews A, Oettinger MA. Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1. Mol Cell. 1998 Dec; 2(6):829-39. PMID: 9885570.
    View in: PubMed
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