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Peter Myung-Hoon Kang, M.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL091998 (KANG, PETER M) Jul 1, 2009 - Jun 30, 2012
    NIH/NHLBI
    Apoptosis inducing factor in cardiac apoptosis
    Role: Principal Investigator
  2. K08HL067091 (KANG, PETER M) Jul 23, 2001 - Mar 31, 2007
    NIH/NHLBI
    Role of Caspase-9 in Heart
    Role: Principal Investigator
  3. R01HL065742 (KANG, PETER M) Jul 12, 2000 - Dec 31, 2006
    NIH/NHLBI
    PHOSPHOINOSITIDE-3 KINASE IN CARDIAC HYPERTROPHY
    Role: Principal Investigator
  4. F32HL009896 (KANG, PETER M) May 30, 1998
    NIH/NHLBI
    REGULATION OF HYPOXIA INDUCED CARDIAC APOPTOSIS
    Role: Principal Investigator
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.
Cardiac Physiology Core Laboratory (BIDMC) - Core services (16), Instruments (4), Protocols (8) and Software (2)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Choi S, Han SI, Jung D, Hwang HJ, Lim C, Bae S, Park OK, Tschabrunn CM, Lee M, Bae SY, Yu JW, Ryu JH, Lee SW, Park K, Kang PM, Lee WB, Nezafat R, Hyeon T, Kim DH. Highly conductive, stretchable and biocompatible Ag-Au core-sheath nanowire composite for wearable and implantable bioelectronics. Nat Nanotechnol. 2018 Nov; 13(11):1048-1056. PMID: 30104619.
    View in: PubMed
  2. Kim KS, Song CG, Kang PM. Targeting Oxidative Stress Using Nanoparticles as a Theranostic Strategy for Cardiovascular Diseases. Antioxid Redox Signal. 2019 Feb 10; 30(5):733-746. PMID: 29228781.
    View in: PubMed
  3. Resch JM, Fenselau H, Madara JC, Wu C, Campbell JN, Lyubetskaya A, Dawes BA, Tsai LT, Li MM, Livneh Y, Ke Q, Kang PM, Fejes-Tóth G, Náray-Fejes-Tóth A, Geerling JC, Lowell BB. Aldosterone-Sensing Neurons in the NTS Exhibit State-Dependent Pacemaker Activity and Drive Sodium Appetite via Synergy with Angiotensin II Signaling. Neuron. 2017 Sep 27; 96(1):190-206.e7. PMID: 28957668.
    View in: PubMed
  4. Khedkar SA, Samad MA, Choudhury S, Lee JY, Zhang D, Thadhani RI, Karumanchi SA, Rigby AC, Kang PM. Identification of Novel Non-secosteroidal Vitamin D Receptor Agonists with Potent Cardioprotective Effects and ??devoid of Hypercalcemia. Sci Rep. 2017 Aug 16; 7(1):8427. PMID: 28814738.
    View in: PubMed
  5. Sitohy B, Chang S, Sciuto TE, Masse E, Shen M, Kang PM, Jaminet SC, Benjamin LE, Bhatt RS, Dvorak AM, Nagy JA, Dvorak HF. Early Actions of Anti-Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor Receptor Drugs on Angiogenic Blood Vessels. Am J Pathol. 2017 Oct; 187(10):2337-2347. PMID: 28736316.
    View in: PubMed
  6. Eshun D, Saraf R, Bae S, Jeganathan J, Mahmood F, Dilmen S, Ke Q, Lee D, Kang PM, Matyal R. Neuropeptide Y3-36 incorporated into PVAX nanoparticle improves functional blood flow in a murine model of hind limb ischemia. J Appl Physiol (1985). 2017 Jun 01; 122(6):1388-1397. PMID: 28302707.
    View in: PubMed
  7. Bae S, Park M, Kang C, Dilmen S, Kang TH, Kang DG, Ke Q, Lee SU, Lee D, Kang PM. Hydrogen Peroxide-Responsive Nanoparticle Reduces Myocardial Ischemia/Reperfusion Injury. J Am Heart Assoc. 2016 11 14; 5(11). PMID: 27930351.
    View in: PubMed
  8. Pal R, Ke Q, Pihan GA, Yesilaltay A, Penman ML, Wang L, Chitraju C, Kang PM, Krieger M, Kocher O. Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease. Am J Physiol Heart Circ Physiol. 2016 12 01; 311(6):H1392-H1408. PMID: 27694217.
    View in: PubMed
  9. Burke SD, Zsengellér ZK, Khankin EV, Lo AS, Rajakumar A, DuPont JJ, McCurley A, Moss ME, Zhang D, Clark CD, Wang A, Seely EW, Kang PM, Stillman IE, Jaffe IZ, Karumanchi SA. Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia. J Clin Invest. 2016 07 01; 126(7):2561-74. PMID: 27270170.
    View in: PubMed
  10. Kolyada A, Ke Q, Karageorgos I, Mahlawat P, Barrios DA, Kang PM, Beglova N. Soluble analog of ApoER2 targeting beta2-glycoprotein I in immune complexes counteracts hypertension in lupus-prone mice with spontaneous antiphospholipid syndrome. J Thromb Haemost. 2016 06; 14(6):1298-307. PMID: 26990752.
    View in: PubMed
  11. Yuan L, Chan GC, Beeler D, Janes L, Spokes KC, Dharaneeswaran H, Mojiri A, Adams WJ, Sciuto T, Garcia-Cardeña G, Molema G, Kang PM, Jahroudi N, Marsden PA, Dvorak A, Regan ER, Aird WC. A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity. Nat Commun. 2016 Jan 08; 7:10160. PMID: 26744078.
    View in: PubMed
  12. Lee D, Park S, Bae S, Jeong D, Park M, Kang C, Yoo W, Samad MA, Ke Q, Khang G, Kang PM. Hydrogen peroxide-activatable antioxidant prodrug as a targeted therapeutic agent for ischemia-reperfusion injury. Sci Rep. 2015 Nov 13; 5:16592. PMID: 26563741; PMCID: PMC4643254.
  13. Kim KS, Lee D, Song CG, Kang PM. Reactive oxygen species-activated nanomaterials as theranostic agents. Nanomedicine (Lond). 2015; 10(17):2709-23. PMID: 26328770; PMCID: PMC4612518.
  14. Ke Q, Samad MA, Bae S, Chaplin DJ, Kang PM. Exaggerated hypertensive response to combretastatin A-4 phosphate in hypertensive rats: Effective pharmacological inhibition by diltiazem. Vascul Pharmacol. 2015 Nov; 74:73-79. PMID: 25989107.
    View in: PubMed
  15. Cho BR, Ryu DR, Lee KS, Lee DK, Bae S, Kang DG, Ke Q, Singh SS, Ha KS, Kwon YG, Lee D, Kang PM, Kim YM. p-Hydroxybenzyl alcohol-containing biodegradable nanoparticle improves functional blood flow through angiogenesis in a mouse model of hindlimb ischemia. Biomaterials. 2015; 53:679-87. PMID: 25890763.
    View in: PubMed
  16. Samad MA, Kim UK, Kang JJ, Ke Q, Kang PM. Endothelin A receptor antagonist, atrasentan, attenuates renal and cardiac dysfunction in Dahl salt-hypertensive rats in a blood pressure independent manner. PLoS One. 2015; 10(3):e0121664. PMID: 25775254; PMCID: PMC4361570.
  17. Tyler PD, Kang PM. Diagnostic and Therapeutic Nanoparticles in Cardiovascular Diseases. Curr Pharm Des. 2015; 21(42):6070-80. PMID: 26503151.
    View in: PubMed
  18. Ikenaga N, Liu SB, Sverdlov DY, Yoshida S, Nasser I, Ke Q, Kang PM, Popov Y. A new Mdr2(-/-) mouse model of sclerosing cholangitis with rapid fibrosis progression, early-onset portal hypertension, and liver cancer. Am J Pathol. 2015 Feb; 185(2):325-34. PMID: 25478810.
    View in: PubMed
  19. Lauriol J, Keith K, Jaffré F, Couvillon A, Saci A, Goonasekera SA, McCarthy JR, Kessinger CW, Wang J, Ke Q, Kang PM, Molkentin JD, Carpenter C, Kontaridis MI. RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis. Sci Signal. 2014 Oct 21; 7(348):ra100. PMID: 25336613; PMCID: PMC4300109.
  20. Choudhury S, Bae S, Ke Q, Lee JY, Singh SS, St-Arnaud R, Monte FD, Kang PM. Abnormal calcium handling and exaggerated cardiac dysfunction in mice with defective vitamin d signaling. PLoS One. 2014; 9(9):e108382. PMID: 25268137; PMCID: PMC4182450.
  21. Dharaneeswaran H, Abid MR, Yuan L, Dupuis D, Beeler D, Spokes KC, Janes L, Sciuto T, Kang PM, Jaminet SS, Dvorak A, Grant MA, Regan ER, Aird WC. FOXO1-mediated activation of Akt plays a critical role in vascular homeostasis. Circ Res. 2014 Jul 07; 115(2):238-251. PMID: 24874427; PMCID: PMC4961050.
  22. Park S, Yoon J, Bae S, Park M, Kang C, Ke Q, Lee D, Kang PM. Therapeutic use of H2O2-responsive anti-oxidant polymer nanoparticles for doxorubicin-induced cardiomyopathy. Biomaterials. 2014 Jul; 35(22):5944-53. PMID: 24767791.
    View in: PubMed
  23. Holwerda KM, Burke SD, Faas MM, Zsengeller Z, Stillman IE, Kang PM, van Goor H, McCurley A, Jaffe IZ, Karumanchi SA, Lely AT. Hydrogen sulfide attenuates sFlt1-induced hypertension and renal damage by upregulating vascular endothelial growth factor. J Am Soc Nephrol. 2014 Apr; 25(4):717-25. PMID: 24335973; PMCID: PMC3968492.
  24. Lee D, Bae S, Ke Q, Lee J, Song B, Karumanchi SA, Khang G, Choi HS, Kang PM. Hydrogen peroxide-responsive copolyoxalate nanoparticles for detection and therapy of ischemia-reperfusion injury. J Control Release. 2013 Dec 28; 172(3):1102-10. PMID: 24096013; PMCID: PMC4389767.
  25. Kwon J, Kim J, Park S, Khang G, Kang PM, Lee D. Inflammation-responsive antioxidant nanoparticles based on a polymeric prodrug of vanillin. Biomacromolecules. 2013 May 13; 14(5):1618-26. PMID: 23590189.
    View in: PubMed
  26. Bae S, Singh SS, Yu H, Lee JY, Cho BR, Kang PM. Vitamin D signaling pathway plays an important role in the development of heart failure after myocardial infarction. J Appl Physiol (1985). 2013 Apr; 114(8):979-87. PMID: 23429874; PMCID: PMC3633431.
  27. Lee D, Bae S, Hong D, Lim H, Yoon JH, Hwang O, Park S, Ke Q, Khang G, Kang PM. H2O2-responsive molecularly engineered polymer nanoparticles as ischemia/reperfusion-targeted nanotherapeutic agents. Sci Rep. 2013; 3:2233. PMID: 23868607; PMCID: PMC3715762.
  28. Choi JH, Ke Q, Bae S, Lee JY, Kim YJ, Kim UK, Arbeeny C, Thadhani R, Kang PM. Doxercalciferol, a pro-hormone of vitamin D, prevents the development of cardiac hypertrophy in rats. J Card Fail. 2011 Dec; 17(12):1051-8. PMID: 22123370; PMCID: PMC3226953.
  29. Bae S, Yalamarti B, Ke Q, Choudhury S, Yu H, Karumanchi SA, Kroeger P, Thadhani R, Kang PM. Preventing progression of cardiac hypertrophy and development of heart failure by paricalcitol therapy in rats. Cardiovasc Res. 2011 Sep 01; 91(4):632-9. PMID: 21565836; PMCID: PMC3156906.
  30. Choudhury S, Bae S, Ke Q, Lee JY, Kim J, Kang PM. Mitochondria to nucleus translocation of AIF in mice lacking Hsp70 during ischemia/reperfusion. Basic Res Cardiol. 2011 May; 106(3):397-407. PMID: 21387140; PMCID: PMC3205442.
  31. Singh SS, Kang PM. Mechanisms and inhibitors of apoptosis in cardiovascular diseases. Curr Pharm Des. 2011; 17(18):1783-93. PMID: 21631422.
    View in: PubMed
  32. Kang PM. Novel pharmacological therapies for cardiac hypertrophy and heart failure. Curr Pharm Des. 2011; 17(18):1773. PMID: 21631418.
    View in: PubMed
  33. Bae S, Siu PM, Choudhury S, Ke Q, Choi JH, Koh YY, Kang PM. Delayed activation of caspase-independent apoptosis during heart failure in transgenic mice overexpressing caspase inhibitor CrmA. Am J Physiol Heart Circ Physiol. 2010 Nov; 299(5):H1374-81. PMID: 20833960; PMCID: PMC2993210.
  34. Kim NH, Kang PM. Apoptosis in cardiovascular diseases: mechanism and clinical implications. Korean Circ J. 2010 Jul; 40(7):299-305. PMID: 20664736; PMCID: PMC2910284.
  35. Kang PB, Lidov HG, White AJ, Mitchell M, Balasubramanian A, Estrella E, Bennett RR, Darras BT, Shapiro FD, Bambach BJ, Kurtzberg J, Gussoni E, Kunkel LM. Inefficient dystrophin expression after cord blood transplantation in Duchenne muscular dystrophy. Muscle Nerve. 2010 Jun; 41(6):746-50. PMID: 20513101; PMCID: PMC2965738.
  36. Bae S, Ke Q, Koh YY, Lee W, Choi JH, Kang PM, Morgan JP. Exacerbation of acute viral myocarditis by tobacco smoke is associated with increased viral load and cardiac apoptosis. Can J Physiol Pharmacol. 2010 May; 88(5):568-75. PMID: 20555426.
    View in: PubMed
  37. Lee W, Kang PM. Vitamin D deficiency and cardiovascular disease: Is there a role for vitamin D therapy in heart failure? Curr Opin Investig Drugs. 2010 Mar; 11(3):309-14. PMID: 20178044.
    View in: PubMed
  38. Choudhury S, Bae S, Kumar SR, Ke Q, Yalamarti B, Choi JH, Kirshenbaum LA, Kang PM. Role of AIF in cardiac apoptosis in hypertrophic cardiomyocytes from Dahl salt-sensitive rats. Cardiovasc Res. 2010 Jan 01; 85(1):28-37. PMID: 19633014; PMCID: PMC2791051.
  39. Ke Q, Bodyak N, Rigor DL, Hurst NW, Chaplin DJ, Kang PM. Pharmacological inhibition of the hypertensive response to combretastatin A-4 phosphate in rats. Vascul Pharmacol. 2009 Nov-Dec; 51(5-6):337-43. PMID: 19737629.
    View in: PubMed
  40. Kang PM, Ruel M, Sellke FW. Highlights from the 2008 American Heart Association scientific session. J Thorac Cardiovasc Surg. 2009 Mar; 137(3):791-4. PMID: 19258129.
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  41. Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT. MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009 Apr; 29(8):2193-204. PMID: 19188439; PMCID: PMC2663304.
  42. Rigor DL, Bodyak N, Bae S, Choi JH, Zhang L, Ter-Ovanesyan D, He Z, McMullen JR, Shioi T, Izumo S, King GL, Kang PM. Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase Cbeta2 in the regulation of physiologic developmental hypertrophy and heart function. Am J Physiol Heart Circ Physiol. 2009 Mar; 296(3):H566-72. PMID: 19122165; PMCID: PMC2660227.
  43. Kim YS, Park HJ, Hong MH, Kang PM, Morgan JP, Jeong MH, Cho JG, Park JC, Ahn Y. TNF-alpha enhances engraftment of mesenchymal stem cells into infarcted myocardium. Front Biosci (Landmark Ed). 2009 Jan 01; 14:2845-56. PMID: 19273239.
    View in: PubMed
  44. Wu G, Rana JS, Wykrzykowska J, Du Z, Ke Q, Kang P, Li J, Laham RJ. Exercise-induced expression of VEGF and salvation of myocardium in the early stage of myocardial infarction. Am J Physiol Heart Circ Physiol. 2009 Feb; 296(2):H389-95. PMID: 19060119; PMCID: PMC2643900.
  45. Yano K, Okada Y, Beldi G, Shih SC, Bodyak N, Okada H, Kang PM, Luscinskas W, Robson SC, Carmeliet P, Karumanchi SA, Aird WC. Elevated levels of placental growth factor represent an adaptive host response in sepsis. J Exp Med. 2008 Oct 27; 205(11):2623-31. PMID: 18852292; PMCID: PMC2571936.
  46. Kontaridis MI, Yang W, Bence KK, Cullen D, Wang B, Bodyak N, Ke Q, Hinek A, Kang PM, Liao R, Neel BG. Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways. Circulation. 2008 Mar 18; 117(11):1423-35. PMID: 18316486; PMCID: PMC2394674.
  47. Bae S, Yalamarti B, Kang PM. Role of caspase-independent apoptosis in cardiovascular diseases. Front Biosci. 2008 Jan 01; 13:2495-503. PMID: 17981729.
    View in: PubMed
  48. Kang PB, Feener CA, Estrella E, Thorne M, White AJ, Darras BT, Amato AA, Kunkel LM. LGMD2I in a North American population. BMC Musculoskelet Disord. 2007 Nov 24; 8:115. PMID: 18036232; PMCID: PMC2216011.
  49. Bodyak N, Ayus JC, Achinger S, Shivalingappa V, Ke Q, Chen YS, Rigor DL, Stillman I, Tamez H, Kroeger PE, Wu-Wong RR, Karumanchi SA, Thadhani R, Kang PM. Activated vitamin D attenuates left ventricular abnormalities induced by dietary sodium in Dahl salt-sensitive animals. Proc Natl Acad Sci U S A. 2007 Oct 23; 104(43):16810-5. PMID: 17942703; PMCID: PMC2040477.
  50. Bodyak N, Rigor DL, Chen YS, Han Y, Bisping E, Pu WT, Kang PM. Uncoupling protein 2 modulates cell viability in adult rat cardiomyocytes. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H829-35. PMID: 17468330.
    View in: PubMed
  51. Siu PM, Bae S, Bodyak N, Rigor DL, Kang PM. Response of caspase-independent apoptotic factors to high salt diet-induced heart failure. J Mol Cell Cardiol. 2007 Mar; 42(3):678-86. PMID: 17292393; PMCID: PMC1855196.
  52. Lim SY, Kim YS, Ahn Y, Jeong MH, Rok LS, Kim JH, Kim KH, Park HW, Kim W, Cho JG, Park JC, Kang PM, Schwartz RS, Kang JC. The effects of granulocyte-colony stimulating factor in bare stent and sirolimus-eluting stent in pigs following myocardial infarction. Int J Cardiol. 2007 Jun 12; 118(3):304-11. PMID: 17052793.
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  53. Bisping E, Ikeda S, Kong SW, Tarnavski O, Bodyak N, McMullen JR, Rajagopal S, Son JK, Ma Q, Springer Z, Kang PM, Izumo S, Pu WT. Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14471-6. PMID: 16983087; PMCID: PMC1636702.
  54. Han Y, Chen YS, Liu Z, Bodyak N, Rigor D, Bisping E, Pu WT, Kang PM. Overexpression of HAX-1 protects cardiac myocytes from apoptosis through caspase-9 inhibition. Circ Res. 2006 Aug 18; 99(4):415-23. PMID: 16857965.
    View in: PubMed
  55. Yano K, Liaw PC, Mullington JM, Shih SC, Okada H, Bodyak N, Kang PM, Toltl L, Belikoff B, Buras J, Simms BT, Mizgerd JP, Carmeliet P, Karumanchi SA, Aird WC. Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality. J Exp Med. 2006 Jun 12; 203(6):1447-58. PMID: 16702604; PMCID: PMC2118329.
  56. Lim SY, Kim YS, Ahn Y, Jeong MH, Hong MH, Joo SY, Nam KI, Cho JG, Kang PM, Park JC. The effects of mesenchymal stem cells transduced with Akt in a porcine myocardial infarction model. Cardiovasc Res. 2006 Jun 01; 70(3):530-42. PMID: 16563361.
    View in: PubMed
  57. He Z, Opland DM, Way KJ, Ueki K, Bodyak N, Kang PM, Izumo S, Kulkarni RN, Wang B, Liao R, Kahn CR, King GL. Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia. Arterioscler Thromb Vasc Biol. 2006 Apr; 26(4):787-93. PMID: 16469952.
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  58. Kang PB, Azad AK, Torrelles JB, Kaufman TM, Beharka A, Tibesar E, DesJardin LE, Schlesinger LS. The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis. J Exp Med. 2005 Oct 03; 202(7):987-99. PMID: 16203868; PMCID: PMC2213176.
  59. Kang PB, Kho AT, Sanoudou D, Haslett JN, Dow CP, Han M, Blasko JM, Lidov HG, Beggs AH, Kunkel LM. Variations in gene expression among different types of human skeletal muscle. Muscle Nerve. 2005 Oct; 32(4):483-91. PMID: 15962335.
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  60. Kang PB, Preston DC, Raynor EM. Involvement of superficial peroneal sensory nerve in common peroneal neuropathy. Muscle Nerve. 2005 Jun; 31(6):725-9. PMID: 15806552.
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  61. Kong SW, Bodyak N, Yue P, Liu Z, Brown J, Izumo S, Kang PM. Genetic expression profiles during physiological and pathological cardiac hypertrophy and heart failure in rats. Physiol Genomics. 2005 Mar 21; 21(1):34-42. PMID: 15623566.
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  62. Parungo CP, Ohnishi S, De Grand AM, Laurence RG, Soltesz EG, Colson YL, Kang PM, Mihaljevic T, Cohn LH, Frangioni JV. In vivo optical imaging of pleural space drainage to lymph nodes of prognostic significance. Ann Surg Oncol. 2004 Dec; 11(12):1085-92. PMID: 15545502.
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  63. Wu J, Parungo C, Wu G, Kang PM, Laham RJ, Sellke FW, Simons M, Li J. PR39 inhibits apoptosis in hypoxic endothelial cells: role of inhibitor apoptosis protein-2. Circulation. 2004 Apr 06; 109(13):1660-7. PMID: 15023888.
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  64. Kang PM, Yue P, Liu Z, Tarnavski O, Bodyak N, Izumo S. Alterations in apoptosis regulatory factors during hypertrophy and heart failure. Am J Physiol Heart Circ Physiol. 2004 Jul; 287(1):H72-80. PMID: 15001440.
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  65. Sanoudou D, Kang PB, Haslett JN, Han M, Kunkel LM, Beggs AH. Transcriptional profile of postmortem skeletal muscle. Physiol Genomics. 2004 Jan 15; 16(2):222-8. PMID: 14625377.
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  66. Kang PB, Lidov HG, David WS, Torres A, Anthony DC, Jones HR, Darras BT. Diagnostic value of electromyography and muscle biopsy in arthrogryposis multiplex congenita. Ann Neurol. 2003 Dec; 54(6):790-5. PMID: 14681888.
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  67. McMullen JR, Shioi T, Huang WY, Zhang L, Tarnavski O, Bisping E, Schinke M, Kong S, Sherwood MC, Brown J, Riggi L, Kang PM, Izumo S. The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway. J Biol Chem. 2004 Feb 06; 279(6):4782-93. PMID: 14597618.
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  68. McMullen JR, Shioi T, Zhang L, Tarnavski O, Sherwood MC, Kang PM, Izumo S. Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12355-60. PMID: 14507992; PMCID: PMC218762.
  69. Kang PB, Hoffman SN, Krimitsos E, Rutkove SB. Ambulatory foot temperature measurement: a new technique in polyneuropathy evaluation. Muscle Nerve. 2003 Jun; 27(6):737-42. PMID: 12766986.
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  70. Kang PM, Izumo S. Apoptosis in heart: basic mechanisms and implications in cardiovascular diseases. Trends Mol Med. 2003 Apr; 9(4):177-82. PMID: 12727144.
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  71. Kasahara H, Ueyama T, Wakimoto H, Liu MK, Maguire CT, Converso KL, Kang PM, Manning WJ, Lawitts J, Paul DL, Berul CI, Izumo S. Nkx2.5 homeoprotein regulates expression of gap junction protein connexin 43 and sarcomere organization in postnatal cardiomyocytes. J Mol Cell Cardiol. 2003 Mar; 35(3):243-56. PMID: 12676539.
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  72. Bodyak N, Kang PM, Hiromura M, Sulijoadikusumo I, Horikoshi N, Khrapko K, Usheva A. Gene expression profiling of the aging mouse cardiac myocytes. Nucleic Acids Res. 2002 Sep 01; 30(17):3788-94. PMID: 12202764; PMCID: PMC137419.
  73. Shioi T, McMullen JR, Kang PM, Douglas PS, Obata T, Franke TF, Cantley LC, Izumo S. Akt/protein kinase B promotes organ growth in transgenic mice. Mol Cell Biol. 2002 Apr; 22(8):2799-809. PMID: 11909972; PMCID: PMC133704.
  74. Aoki H, Kang PM, Hampe J, Yoshimura K, Noma T, Matsuzaki M, Izumo S. Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes. J Biol Chem. 2002 Mar 22; 277(12):10244-50. PMID: 11786558.
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  75. Kang PM, Yue P, Izumo S. New insights into the role of apoptosis in cardiovascular disease. Circ J. 2002 Jan; 66(1):1-9. PMID: 11999654.
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  76. Kang PM, Izumo S. Morphological changes associated with reoxygenation in adult cardiac myocytes. J Cell Mol Med. 2001 Apr-Jun; 5(2):198-9. PMID: 12067503.
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  77. Liao HS, Kang PM, Nagashima H, Yamasaki N, Usheva A, Ding B, Lorell BH, Izumo S. Cardiac-specific overexpression of cyclin-dependent kinase 2 increases smaller mononuclear cardiomyocytes. Circ Res. 2001 Mar 02; 88(4):443-50. PMID: 11230113.
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  78. Kang PM, Haunstetter A, Aoki H, Usheva A, Izumo S. Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation. Circ Res. 2000 Jul 21; 87(2):118-25. PMID: 10903995.
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  79. Kang PM, Izumo S. Apoptosis and heart failure: A critical review of the literature. Circ Res. 2000 Jun 09; 86(11):1107-13. PMID: 10850960.
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  80. Shioi T, Kang PM, Douglas PS, Hampe J, Yballe CM, Lawitts J, Cantley LC, Izumo S. The conserved phosphoinositide 3-kinase pathway determines heart size in mice. EMBO J. 2000 Jun 01; 19(11):2537-48. PMID: 10835352; PMCID: PMC212739.
  81. Kang PM, Izumo S. Apoptosis in heart failure: is there light at the end of the tunnel (TUNEL)? J Card Fail. 2000 Mar; 6(1):43-6. PMID: 10746818.
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  82. Kang PM, Nakouzi A, Simpson T, Scheuer J, Buttrick PM. Role of endogenous renin-angiotensin system in c-fos activation and PKC-epsilon translocation in adult rat hearts. Am J Physiol. 1996 Jun; 270(6 Pt 2):H2177-83. PMID: 8764271.
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  83. Kang PM, Lawrence C, Khan GA, Hays RM. Fulminating systemic capillary leak syndrome with lymphocytosis and hypogammaglobulinemia. Ren Fail. 1995 Sep; 17(5):615-7. PMID: 8570875.
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  84. Kang PM, Landau AJ, Eberhardt RT, Frishman WH. Angiotensin II receptor antagonists: a new approach to blockade of the renin-angiotensin system. Am Heart J. 1994 May; 127(5):1388-401. PMID: 8172070.
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  85. Eberhardt RT, Kevak RM, Kang PM, Frishman WH. Angiotensin II receptor blockade: an innovative approach to cardiovascular pharmacotherapy. J Clin Pharmacol. 1993 Nov; 33(11):1023-38. PMID: 8300885.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.