Harvard Catalyst Profiles

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Christine B Sieberg, Ph.D.

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Other Positions

Boston Children's Hospital/Pain Treatment Service , Boston, MA 8/2011Postdoctoral Fellowship- Clinical Psychology; focus Pediatric Pain
Alpert Warren Medical School of Brown University, Providence, RI6/2009Predoctoral Clinical Psychology Internship- focus in Child & Pediatric Health Psychology
University of Rhode Island , Kingston, RIPhD08/2009Clinical Psychology; focus in Child & Health Psychology
Boston College , Chestnut Hill, MAMA05/2004Applied Developmental & Educational Psychology
Harvard University , Cambridge, MAEdM06/2003Risk & Prevention in Children
Boston College , Chestnut Hill, MABA05/2002Elementary/Special Needs Education & Human Development; focus in Human Services
Program Award for a Culture of Excellence in Mentoring (PACEM)


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R35GM142676 (SIEBERG, CHRISTINE BARRETT) Sep 1, 2021 - Jun 30, 2026
    Chronic Postsurgical Pain Across the Lifespan: Brain State and Treatment
    Role: Principal Investigator
  2. R21HD096358 (MISSMER, STACEY ANN) May 1, 2019 - Apr 30, 2021
    Harnessing biomarker and phenotypic diversity among adolescents and women with endometriosis to advance personalized medicine for diagnosis and pain remediation
    Role: Co-Investigator
  3. R01HD094842 (MISSMER, STACEY ANN) Aug 1, 2018 - Apr 30, 2023
    What is Endometriosis? Deep Phenotyping to Advance Diagnosis and Treatment
    Role: Co-Investigator
  4. K23GM123372 (SIEBERG, CHRISTINE BARRETT) Sep 5, 2016 - Aug 31, 2021
    Pediatric Persistent Post-surgical Pain: From Animals to Application
    Role: Principal Investigator

Featured Content

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sieberg CB, Lunde CE, Wong C, Manganella J, Starkweather AR, Sethna N, Perry-Eaddy MA. Pilot Investigation of Somatosensory Functioning and Pain Catastrophizing in Pediatric Spinal Fusion Surgery. Pain Manag Nurs. 2023 02; 24(1):27-34. PMID: 36564325; PMCID: PMC9925410.
    Citations:    Fields:    Translation:Humans
  2. Szabo E, Timmers I, Borsook D, Simons LE, Sieberg CB. Altered anterior insula functional connectivity in adolescent and young women with endometriosis-associated pain: Pilot resting-state fMRI study. Eur J Paediatr Neurol. 2022 Nov; 41:80-90. PMID: 36375399.
    Citations:    Fields:    Translation:Humans
  3. Jotwani ML, Wu Z, Lunde CE, Sieberg CB. The missing mechanistic link: Improving behavioral treatment efficacy for pediatric chronic pain. Front Pain Res (Lausanne). 2022; 3:1022699. PMID: 36313218.
  4. Sasamoto N, Shafrir AL, Wallace BM, Vitonis AF, Fraer CJ, Sadler Gallagher J, DePari M, Ghiasi M, Laufer MR, Sieberg CB, DiVasta AD, Schrepf A, As-Sanie S, Terry KL, Missmer SA. Trends in pelvic pain symptoms over 2 years of follow-up among adolescents and young adults with and without endometriosis. Pain. 2023 03 01; 164(3):613-624. PMID: 35947080; PMCID: PMC9908772.
    Citations:    Fields:    Translation:Humans
  5. Szabo E, Chang YC, Shulman J, Sieberg CB, Sethna NF, Borsook D, Holmes SA, Lebel AA. Alterations in the structure and function of the brain in adolescents with new daily persistent headache: A pilot MRI study. Headache. 2022 07; 62(7):858-869. PMID: 35861130.
    Citations: 2     Fields:    Translation:Humans
  6. Sieberg CB, Karunakaran KD, Kussman B, Borsook D. Preventing pediatric chronic postsurgical pain: Time for increased rigor. Can J Pain. 2022; 6(2):73-84. PMID: 35528039; PMCID: PMC9067470.
    Citations: 2     
  7. Lunde CE, Fisher E, Donovan E, Serbic D, Sieberg CB. Cutting the cord? Parenting emerging adults with chronic pain. Paediatr Neonatal Pain. 2022 Sep; 4(3):136-147. PMID: 36188158; PMCID: PMC9485821.
  8. Lunde CE, Spigel R, Gordon CM, Sieberg CB. Beyond the Binary: Sexual and Reproductive Health Considerations for Transgender and Gender Expansive Adolescents. Front Reprod Health. 2021; 3:670919. PMID: 36304055.
  9. Holmes SA, Karapanagou A, Staffa SJ, Zurakowski D, Borra R, Simons LE, Sieberg C, Lebel A, Borsook D. DTI and MTR Measures of Nerve Fiber Integrity in Pediatric Patients With Ankle Injury. Front Pediatr. 2021; 9:656843. PMID: 34660471; PMCID: PMC8511521.
  10. Pierce J, Hassett AL, Brummett CM, McAfee J, Sieberg C, Schrepf A, Harte SE. Characterizing Pain and Generalized Sensory Sensitivity According to Trauma History Among Patients With Knee Osteoarthritis. Ann Behav Med. 2021 08 23; 55(9):853-869. PMID: 33377478; PMCID: PMC8382144.
    Citations: 1     Fields:    Translation:Humans
  11. Shafrir AL, Martel E, Missmer SA, Clauw DJ, Harte SE, As-Sanie S, Sieberg CB. Pelvic floor, abdominal and uterine tenderness in relation to pressure pain sensitivity among women with endometriosis and chronic pelvic pain. Eur J Obstet Gynecol Reprod Biol. 2021 Sep; 264:247-253. PMID: 34340095; PMCID: PMC8449805.
    Citations: 2     Fields:    Translation:Humans
  12. Szabo E, Green S, Karunakaran KD, Sieberg CB, Elman I, Burstein R, Borsook D. Migraine: interactions between brain's trait and state. CNS Spectr. 2022 10; 27(5):561-569. PMID: 34308820; PMCID: PMC8688585.
    Citations:    Fields:    Translation:Humans
  13. Maallo AMS, Moulton EA, Sieberg CB, Giddon DB, Borsook D, Holmes SA. A lateralized model of the pain-depression dyad. Neurosci Biobehav Rev. 2021 08; 127:876-883. PMID: 34090918; PMCID: PMC8289740.
    Citations: 1     Fields:    Translation:Humans
  14. Corey JR, Heathcote LC, Mahmud F, Kronman C, Mukerji C, McGinnis E, Noel M, Sieberg C, Simons LE. Longitudinal Narrative Analysis of Parent Experiences During Graded Exposure Treatment for Children With Chronic Pain. Clin J Pain. 2021 04 01; 37(4):301-309. PMID: 33555695; PMCID: PMC7953686.
    Citations:    Fields:    Translation:Humans
  15. Sieberg CB, Lebel A, Silliman E, Holmes S, Borsook D, Elman I. Left to themselves: Time to target chronic pain in childhood rare diseases. Neurosci Biobehav Rev. 2021 07; 126:276-288. PMID: 33774086.
    Citations: 1     Fields:    Translation:Humans
  16. Lunde CE, Szabo E, Holmes SA, Borsook D, Sieberg CB. Commentary: Novel Use of Offset Analgesia to Assess Adolescents and Adults with Treatment Resistant Endometriosis-Associated Pain. J Pain Res. 2020; 13:2775-2782. PMID: 33204144; PMCID: PMC7660453.
  17. Eccleston C, Fisher E, Howard RF, Slater R, Forgeron P, Palermo TM, Birnie KA, Anderson BJ, Chambers CT, Crombez G, Ljungman G, Jordan I, Jordan Z, Roberts C, Schechter N, Sieberg CB, Tibboel D, Walker SM, Wilkinson D, Wood C. Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission. Lancet Child Adolesc Health. 2021 01; 5(1):47-87. PMID: 33064998.
    Citations: 47     Fields:    Translation:Humans
  18. Pielech M, Lunde CE, Becker SJ, Vowles KE, Sieberg CB. Comorbid chronic pain and opioid misuse in youth: Knowns, unknowns, and implications for behavioral treatment. Am Psychol. 2020 09; 75(6):811-824. PMID: 32915025; PMCID: PMC9053101.
    Citations: 7     Fields:    Translation:Humans
  19. Perry M, Sieberg CB, Young EE, Baumbauer K, Singh V, Wong C, Starkweather A. The Potential Role of Preoperative Pain, Catastrophizing, and Differential Gene Expression on Pain Outcomes after Pediatric Spinal Fusion. Pain Manag Nurs. 2021 02; 22(1):44-49. PMID: 32771349.
    Citations: 6     Fields:    Translation:Humans
  20. Lunde CE, Sieberg CB. Walking the Tightrope: A Proposed Model of Chronic Pain and Stress. Front Neurosci. 2020; 14:270. PMID: 32273840.
    Citations: 8     
  21. Simons LE, Vlaeyen JWS, Declercq L, Smith AM, Beebe J, Hogan M, Li E, Kronman CA, Mahmud F, Corey JR, Sieberg CB, Ploski C. Avoid or engage? Outcomes of graded exposure in youth with chronic pain using a sequential replicated single-case randomized design. Pain. 2020 03; 161(3):520-531. PMID: 31693541; PMCID: PMC7126333.
    Citations: 16     Fields:    Translation:Humans
  22. Sieberg CB, Lunde CE, Borsook D. Endometriosis and pain in the adolescent- striking early to limit suffering: A narrative review. Neurosci Biobehav Rev. 2020 01; 108:866-876. PMID: 31862211; PMCID: PMC7175958.
    Citations: 11     Fields:    Translation:HumansAnimals
  23. Peng K, Cheung K, Lee A, Sieberg C, Borsook D, Upadhyay J. Longitudinal Evaluation of Pain, Flare-Up, and Emotional Health in Fibrodysplasia Ossificans Progressiva: Analyses of the International FOP Registry. JBMR Plus. 2019 Aug; 3(8):e10181. PMID: 31485551.
    Citations: 10     
  24. Heathcote LC, Williams SE, Smith AM, Sieberg CB, Simons LE. Parent Attributions of Ambiguous Symptoms in Their Children: A Preliminary Measure Validation in Parents of Children with Chronic Pain. Children (Basel). 2018 Jun 13; 5(6). PMID: 29899299; PMCID: PMC6025587.
    Citations: 5     
  25. Sieberg CB, Taras C, Gomaa A, Nickerson C, Wong C, Ward C, Baskozos G, Bennett DLH, Ramirez JD, Themistocleous AC, Rice ASC, Shillo PR, Tesfaye S, Edwards RR, Andrews NA, Berde C, Costigan M. Neuropathic pain drives anxiety behavior in mice, results consistent with anxiety levels in diabetic neuropathy patients. Pain Rep. 2018 May; 3(3):e651. PMID: 29922743; PMCID: PMC5999418.
    Citations: 19     
  26. Borsook D, Youssef AM, Barakat N, Sieberg CB, Elman I. Subliminal (latent) processing of pain and its evolution to conscious awareness. Neurosci Biobehav Rev. 2018 05; 88:1-15. PMID: 29476771; PMCID: PMC5985199.
    Citations: 5     Fields:    Translation:HumansAnimals
  27. Simons LE, Sieberg CB, Conroy C, Randall ET, Shulman J, Borsook D, Berde C, Sethna NF, Logan DE. Children With Chronic Pain: Response Trajectories After Intensive Pain Rehabilitation Treatment. J Pain. 2018 02; 19(2):207-218. PMID: 29102693; PMCID: PMC5803450.
    Citations: 23     Fields:    Translation:Humans
  28. Sieberg CB, Manganella J, Manalo G, Simons LE, Hresko MT. Predicting Postsurgical Satisfaction in Adolescents With Idiopathic Scoliosis: The Role of Presurgical Functioning and Expectations. J Pediatr Orthop. 2017 Dec; 37(8):e548-e551. PMID: 27379786.
    Citations: 2     Fields:    Translation:Humans
  29. Sieberg CB, Klajn J, Wong C, Bowen G, Simons LE, Millis MB. Predictors and trajectories of chronic postoperative pain following hip preservation surgery. J Hip Preserv Surg. 2017 Jan; 4(1):45-53. PMID: 28630720; PMCID: PMC5467405.
    Citations: 7     
  30. Sieberg CB, Smith A, White M, Manganella J, Sethna N, Logan DE. Changes in Maternal and Paternal Pain-Related Attitudes, Behaviors, and Perceptions across Pediatric Pain Rehabilitation Treatment: A Multilevel Modeling Approach. J Pediatr Psychol. 2017 01 01; 42(1):52-64. PMID: 28175324; PMCID: PMC6251571.
    Citations: 8     Fields:    Translation:Humans
  31. Agoston AM, Sieberg CB. Nonpharmacologic Treatment of Pain. Semin Pediatr Neurol. 2016 08; 23(3):220-223. PMID: 27989329.
    Citations: 4     Fields:    Translation:Humans
  32. Nicol AL, Sieberg CB, Clauw DJ, Hassett AL, Moser SE, Brummett CM. The Association Between a History of Lifetime Traumatic Events and Pain Severity, Physical Function, and Affective Distress in Patients With Chronic Pain. J Pain. 2016 12; 17(12):1334-1348. PMID: 27641311.
    Citations: 30     Fields:    Translation:Humans
  33. Sieberg CB, Smith A, White M, Manganella J, Sethna N, Logan DE. Changes in Maternal and Paternal Pain-Related Attitudes, Behaviors, and Perceptions across Pediatric Pain Rehabilitation Treatment: A Multilevel Modeling Approach. J Pediatr Psychol. 2016 Jun 20. PMID: 27325347.
  34. Smith AM, Sieberg CB, Odell S, Randall E, Simons LE. Living Life With My Child's Pain: The Parent Pain Acceptance Questionnaire (PPAQ). Clin J Pain. 2015 Jul; 31(7):633-41. PMID: 25119514.
    Citations: 14     Fields:    Translation:Humans
  35. Simons LE, Sieberg CB. Parents--to help or hinder pain memories in children. Pain. 2015 May; 156(5):761-762. PMID: 25734996; PMCID: PMC4405457.
    Citations: 2     Fields:    Translation:Humans
  36. Sieberg CB, Manganella J. Family Beliefs and Interventions in Pediatric Pain Management. Child Adolesc Psychiatr Clin N Am. 2015 Jul; 24(3):631-45. PMID: 26092744.
    Citations: 6     Fields:    Translation:Humans
  37. Logan DE, Sieberg CB, Conroy C, Smith K, Odell S, Sethna N. Changes in sleep habits in adolescents during intensive interdisciplinary pediatric pain rehabilitation. J Youth Adolesc. 2015 Feb; 44(2):543-55. PMID: 25037910.
    Citations: 12     Fields:    Translation:Humans
  38. Sieberg CB, Simons LE, Edelstein MR, DeAngelis MR, Pielech M, Sethna N, Hresko MT. Pain prevalence and trajectories following pediatric spinal fusion surgery. J Pain. 2013 Dec; 14(12):1694-702. PMID: 24290449.
    Citations: 54     Fields:    Translation:Humans
  39. Pielech M, Sieberg CB, Simons LE. Connecting parents of children with chronic pain through art therapy. Clin Pract Pediatr Psychol. 2013 Sep 01; 1(3):214-226. PMID: 24563827.
    Citations: 4     
  40. Simons LE, Sieberg CB, Coakley RM. Patients with pain are not all the same: considering fear of pain and other individual factors in treatment. Pain Manag. 2013 Mar; 3(2):87-9. PMID: 24645990; PMCID: PMC4060630.
    Citations: 3     Fields:    
  41. Logan DE, Engle LB, Feinstein AB, Sieberg CB, Sparling P, Cohen LL, Conroy C, Driesman D, Masuda A. Ecological system influences in the treatment of pediatric chronic pain. Pain Res Manag. 2012 Nov-Dec; 17(6):407-11. PMID: 23248814.
    Citations: 5     Fields:    Translation:Humans
  42. Simons LE, Sieberg CB, Pielech M, Conroy C, Logan DE. What does it take? Comparing intensive rehabilitation to outpatient treatment for children with significant pain-related disability. J Pediatr Psychol. 2013 Mar; 38(2):213-23. PMID: 23104827.
    Citations: 41     Fields:    Translation:Humans
  43. Logan DE, Conroy C, Sieberg CB, Simons LE. Changes in willingness to self-manage pain among children and adolescents and their parents enrolled in an intensive interdisciplinary pediatric pain treatment program. Pain. 2012 Sep; 153(9):1863-1870. PMID: 22749194.
    Citations: 20     Fields:    Translation:Humans
  44. Simons LE, Sieberg CB, Claar RL. Anxiety and impairment in a large sample of children and adolescents with chronic pain. Pain Res Manag. 2012 Mar-Apr; 17(2):93-7. PMID: 22518371.
    Citations: 33     Fields:    Translation:Humans
  45. Sieberg CB, Huguet A, von Baeyer CL, Seshia S. Psychological interventions for headache in children and adolescents. Can J Neurol Sci. 2012 Jan; 39(1):26-34. PMID: 22384492.
    Citations: 17     Fields:    Translation:Humans
  46. Simons LE, Sieberg CB, Kaczynski KJ. Measuring parent beliefs about child acceptance of pain: a preliminary validation of the Chronic Pain Acceptance Questionnaire, parent report. Pain. 2011 Oct; 152(10):2294-2300. PMID: 21783324.
    Citations: 14     Fields:    Translation:Humans
  47. Sieberg CB, Williams S, Simons LE. Do parent protective responses mediate the relation between parent distress and child functional disability among children with chronic pain? J Pediatr Psychol. 2011 Oct; 36(9):1043-51. PMID: 21742755.
    Citations: 55     Fields:    Translation:Humans
  48. Sieberg CB, Flannery-Schroeder E, Plante W. Children with co-morbid recurrent abdominal pain and anxiety disorders: results from a multiple-baseline intervention study. J Child Health Care. 2011 Jun; 15(2):126-39. PMID: 21685228.
    Citations: 11     Fields:    Translation:Humans
  49. Simons LE, Sieberg CB, Carpino E, Logan D, Berde C. The Fear of Pain Questionnaire (FOPQ): assessment of pain-related fear among children and adolescents with chronic pain. J Pain. 2011 Jun; 12(6):677-86. PMID: 21354866.
    Citations: 77     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.