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Yi Lu, M.D.

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Spinal Cord Injury Research Award
American College of Surgeons Research Scholar


Available: 04/05/22, Expires: 06/01/23

We study axonopathy from mild repetitive traumatic brain injury, especially optic neuropathy, using caveolin based treatment strategy. We study axon regeneration with spinal cord injury, focusing on molecular mechanisms that enhance growth factor related axon growth potential. We study discogenic back pain molecular mechanism and non-opioid pharmacological treatments using microglia related pathways.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Karhade AV, Vasudeva VS, Dasenbrock HH, Lu Y, Gormley WB, Groff MW, Chi JH, Smith TR. Thirty-day readmission and reoperation after surgery for spinal tumors: a National Surgical Quality Improvement Program analysis. Neurosurg Focus. 2016 Aug; 41(2):E5. PMID: 27476847.
    Citations: 17     Fields:    Translation:Humans
  2. Ma Z, Zhang YP, Liu W, Yan G, Li Y, Shields LBE, Walker M, Chen K, Huang W, Kong M, Lu Y, Brommer B, Chen X, Xu XM, Shields CB. A controlled spinal cord contusion for the rhesus macaque monkey. Exp Neurol. 2016 May; 279:261-273. PMID: 26875994.
    Citations: 18     Fields:    Translation:AnimalsCells
  3. Ma Z, Li Y, Zhang YP, Shields LB, Xie Q, Yan G, Liu W, Chen G, Zhang Y, Brommer B, Xu XM, Lu Y, Chen X, Shields CB. Thermal nociception using a modified Hargreaves method in primates and humans. Funct Neurol. 2015 Oct-Dec; 30(4):229-36. PMID: 26727701; PMCID: PMC4758775.
    Citations: 5     Fields:    Translation:Animals
  4. Donnelly DJ, Abd-El-Barr MM, Lu Y. Minimally Invasive Muscle Sparing Posterior-Only Approach for Lumbar Circumferential Decompression and Stabilization to Treat Spine Metastasis--Technical Report. World Neurosurg. 2015 Nov; 84(5):1484-90. PMID: 26100166.
    Citations: 12     Fields:    Translation:Humans
  5. Lu Y, Yeung C, Radmanesh A, Wiemann R, Black PM, Golby AJ. Comparative effectiveness of frame-based, frameless, and intraoperative magnetic resonance imaging-guided brain biopsy techniques. World Neurosurg. 2015 Mar; 83(3):261-8. PMID: 25088233.
    Citations: 18     Fields:    Translation:Humans
  6. Gologorsky Y, Knightly JJ, Lu Y, Chi JH, Groff MW. Improving discharge data fidelity for use in large administrative databases. Neurosurg Focus. 2014 Jun; 36(6):E2. PMID: 24881634.
    Citations: 20     Fields:    Translation:Humans
  7. Lu Y, Belin S, He Z. Signaling regulations of neuronal regenerative ability. Curr Opin Neurobiol. 2014 Aug; 27:135-42. PMID: 24727245.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  8. Lu Y, Klein GT, Wang MY. Can pain be measured objectively? Neurosurgery. 2013 Aug; 73(2):N24-5. PMID: 23867275.
    Citations: 3     Fields:    Translation:Humans
  9. Klein GT, Lu Y, Wang MY. 3D printing and neurosurgery--ready for prime time? World Neurosurg. 2013 Sep-Oct; 80(3-4):233-5. PMID: 23871811.
    Citations: 44     Fields:    Translation:Humans
  10. Lu Y, Wang MY. The identification of a nucleus pulposus progenitor cell population: a tie to the spinal disc degenerative disease? Neurosurgery. 2013 Jun; 72(6):N24-6. PMID: 23685518.
    Citations:    Fields:    Translation:HumansAnimalsCells
  11. Lu Y, Wang MY. Neural stem cell grafts for complete spinal cord injury. Neurosurgery. 2012 Dec; 71(6):N13-5. PMID: 23160392.
    Citations: 6     Fields:    Translation:AnimalsCells
  12. Lu Y, Chi J. Having the brain participate in spinal cord injury recovery. Neurosurgery. 2012 Oct; 71(4):N18-9. PMID: 22989969.
    Citations:    Fields:    Translation:HumansAnimals
  13. Lu Y, Chi JH. Seeing is believing--spinal chamber for spinal cord injury research. Neurosurgery. 2012 Jun; 70(6):N19-20. PMID: 22596008.
    Citations:    Fields:    Translation:Animals
  14. Liu K, Lu Y, Lee JK, Samara R, Willenberg R, Sears-Kraxberger I, Tedeschi A, Park KK, Jin D, Cai B, Xu B, Connolly L, Steward O, Zheng B, He Z. PTEN deletion enhances the regenerative ability of adult corticospinal neurons. Nat Neurosci. 2010 Sep; 13(9):1075-81. PMID: 20694004; PMCID: PMC2928871.
    Citations: 427     Fields:    Translation:AnimalsCells
  15. Slotkin JR, Lu Y, Wood KB. Thoracolumbar spinal trauma in children. Neurosurg Clin N Am. 2007 Oct; 18(4):621-30. PMID: 17991587.
    Citations: 6     Fields:    Translation:Humans
  16. Lu Y, Luo Z, Bregman DB. RNA polymerase II large subunit is cleaved by caspases during DNA damage-induced apoptosis. Biochem Biophys Res Commun. 2002 Aug 30; 296(4):954-61. PMID: 12200141.
    Citations: 6     Fields:    Translation:HumansCells
  17. Lu Y, Mani S, Kandimalla ER, Yu D, Agrawal S, States JC, Bregman DB. The Cockayne syndrome group B DNA repair protein as an anti-cancer target. Int J Oncol. 2001 Dec; 19(6):1089-97. PMID: 11713576.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  18. Luo Z, Zheng J, Lu Y, Bregman DB. Ultraviolet radiation alters the phosphorylation of RNA polymerase II large subunit and accelerates its proteasome-dependent degradation. Mutat Res. 2001 Sep 04; 486(4):259-74. PMID: 11516929.
    Citations: 26     Fields:    Translation:HumansCells
  19. Lu Y, Lian H, Sharma P, Schreiber-Agus N, Russell RG, Chin L, van der Horst GT, Bregman DB. Disruption of the Cockayne syndrome B gene impairs spontaneous tumorigenesis in cancer-predisposed Ink4a/ARF knockout mice. Mol Cell Biol. 2001 Mar; 21(5):1810-8. PMID: 11238917; PMCID: PMC86742.
    Citations: 9     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.