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Eileen Remold-O'Donnell, Ph.D.


Examining the Human Monocyte/Neutrophil Elastase Inhibitor (M/NE1) Gene for Active Site Mutations
Part Time, 09/05/98 - 06/30/99
Role of Elastase and Monocyte /Neutrophil Elastase Inhibitor in Chronic Lung Disease of Infancy
Summer, 06/21/99 - 08/31/99
Role of Neutrophil Proteases and Monocyte Neutrophil Elastase Inhibitor (M/NEI) in Cleavage of Surfactant Protein A
Part Time/Continuation, 09/01/99 - 06/30/00

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AI117440 (REMOLD-O'DONNELL, EILEEN) Feb 15, 2016 - Jan 31, 2018
    Regulation of Th17 immune responses by serpinB1
    Role: Principal Investigator
  2. R21AI103407 (REMOLD-O'DONNELL, EILEEN) Apr 15, 2013 - Mar 31, 2015
    Regulation of NETosis in antibacterial lung defense
    Role: Principal Investigator
  3. R21HL091269 (REMOLD-O'DONNELL, EILEEN) Apr 15, 2009 - Sep 30, 2012
    Impaired integrin-dependent function of WASP-deficient platelets
    Role: Principal Investigator
  4. R21AI072552 (REMOLD-O'DONNELL, EILEEN) Jul 15, 2007 - Jun 30, 2010
    SERPINB1/MNEI: Role in innate immune defense against influenza virus infection
    Role: Principal Investigator
  5. R21HL081407 (REMOLD-O'DONNELL, EILEEN) Jul 1, 2005 - Jun 30, 2009
    Defects of Thymic Output in Wiskott-Aldrich Syndrome
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Hou L, Rao DA, Yuki K, Cooley J, Henderson LA, Jonsson AH, Kaiserman D, Gorman MP, Nigrovic PA, Bird PI, Becher B, Remold-O'Donnell E. SerpinB1 controls encephalitogenic T helper cells in neuroinflammation. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20635-20643. PMID: 31548399.
  2. Burgener SS, Baumann M, Basilico P, Remold-O'Donnell E, Touw IP, Benarafa C. Myeloid conditional deletion and transgenic models reveal a threshold for the neutrophil survival factor Serpinb1. Biol Chem. 2016 09 01; 397(9):897-905. PMID: 27107834.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  3. Martinod K, Witsch T, Farley K, Gallant M, Remold-O'Donnell E, Wagner DD. Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis. J Thromb Haemost. 2016 Mar; 14(3):551-8. PMID: 26712312.
    Citations: 18     Fields:    Translation:AnimalsCells
  4. El Ouaamari A, Dirice E, Gedeon N, Hu J, Zhou JY, Shirakawa J, Hou L, Goodman J, Karampelias C, Qiang G, Boucher J, Martinez R, Gritsenko MA, De Jesus DF, Kahraman S, Bhatt S, Smith RD, Beer HD, Jungtrakoon P, Gong Y, Goldfine AB, Liew CW, Doria A, Andersson O, Qian WJ, Remold-O'Donnell E, Kulkarni RN. SerpinB1 Promotes Pancreatic ß Cell Proliferation. Cell Metab. 2016 Jan 12; 23(1):194-205. PMID: 26701651.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  5. Hou L, Cooley J, Swanson R, Ong PC, Pike RN, Bogyo M, Olson ST, Remold-O'Donnell E. The protease cathepsin L regulates Th17 cell differentiation. J Autoimmun. 2015 Dec; 65:56-63. PMID: 26343333.
    Citations: 6     Fields:    Translation:AnimalsCells
  6. Loison F, Zhu H, Karatepe K, Kasorn A, Liu P, Ye K, Zhou J, Cao S, Gong H, Jenne DE, Remold-O'Donnell E, Xu Y, Luo HR. Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation. J Clin Invest. 2014 Oct; 124(10):4445-58. PMID: 25180606.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  7. Zhao P, Hou L, Farley K, Sundrud MS, Remold-O'Donnell E. SerpinB1 regulates homeostatic expansion of IL-17+ ?d and CD4+ Th17 cells. J Leukoc Biol. 2014 Mar; 95(3):521-30. PMID: 24249741.
    Citations: 6     Fields:    Translation:AnimalsCells
  8. Stolley JM, Gong D, Farley K, Zhao P, Cooley J, Crouch EC, Benarafa C, Remold-O'Donnell E. Increased surfactant protein D fails to improve bacterial clearance and inflammation in serpinB1-/- mice. Am J Respir Cell Mol Biol. 2012 Dec; 47(6):792-9. PMID: 23024061.
    Citations: 1     Fields:    Translation:AnimalsCells
  9. Farley K, Stolley JM, Zhao P, Cooley J, Remold-O'Donnell E. A serpinB1 regulatory mechanism is essential for restricting neutrophil extracellular trap generation. J Immunol. 2012 Nov 01; 189(9):4574-81. PMID: 23002442.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  10. Gong D, Farley K, White M, Hartshorn KL, Benarafa C, Remold-O'Donnell E. Critical role of serpinB1 in regulating inflammatory responses in pulmonary influenza infection. J Infect Dis. 2011 Aug 15; 204(4):592-600. PMID: 21791661.
    Citations: 16     Fields:    Translation:AnimalsCells
  11. Jégot G, Derache C, Castella S, Lahouassa H, Pitois E, Jourdan ML, Remold-O'Donnell E, Kellenberger C, Gauthier F, Korkmaz B. A substrate-based approach to convert SerpinB1 into a specific inhibitor of proteinase 3, the Wegener's granulomatosis autoantigen. FASEB J. 2011 Sep; 25(9):3019-31. PMID: 21670065.
    Citations: 2     Fields:    Translation:HumansCells
  12. Benarafa C, LeCuyer TE, Baumann M, Stolley JM, Cremona TP, Remold-O'Donnell E. SerpinB1 protects the mature neutrophil reserve in the bone marrow. J Leukoc Biol. 2011 Jul; 90(1):21-9. PMID: 21248149.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  13. Cooley J, Sontag MK, Accurso FJ, Remold-O'Donnell E. SerpinB1 in cystic fibrosis airway fluids: quantity, molecular form and mechanism of elastase inhibition. Eur Respir J. 2011 May; 37(5):1083-90. PMID: 20817705.
    Citations: 2     Fields:    Translation:Humans
  14. Remold-O'Donnell E. Lymphocytes with congenitally active WASP. Blood. 2010 Jul 01; 115(26):5283-4. PMID: 20595519.
    Citations:    Fields:    
  15. Davies PL, Spiller OB, Beeton ML, Maxwell NC, Remold-O'Donnell E, Kotecha S. Relationship of proteinases and proteinase inhibitors with microbial presence in chronic lung disease of prematurity. Thorax. 2010 Mar; 65(3):246-51. PMID: 20335295.
    Citations: 10     Fields:    Translation:Humans
  16. Boilard E, Nigrovic PA, Larabee K, Watts GF, Coblyn JS, Weinblatt ME, Massarotti EM, Remold-O'Donnell E, Farndale RW, Ware J, Lee DM. Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Science. 2010 Jan 29; 327(5965):580-3. PMID: 20110505.
    Citations: 243     Fields:    Translation:HumansAnimalsCells
  17. Shcherbina A, Cooley J, Lutskiy MI, Benarafa C, Gilbert GE, Remold-O'Donnell E. WASP plays a novel role in regulating platelet responses dependent on alphaIIbbeta3 integrin outside-in signalling. Br J Haematol. 2010 Feb; 148(3):416-27. PMID: 19863535.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  18. Lutskiy MI, Park JY, Remold SK, Remold-O'Donnell E. Evolution of highly polymorphic T cell populations in siblings with the Wiskott-Aldrich Syndrome. PLoS One. 2008; 3(10):e3444. PMID: 18941616.
    Citations: 7     Fields:    Translation:HumansCells
  19. Goerge T, Ho-Tin-Noe B, Carbo C, Benarafa C, Remold-O'Donnell E, Zhao BQ, Cifuni SM, Wagner DD. Inflammation induces hemorrhage in thrombocytopenia. Blood. 2008 May 15; 111(10):4958-64. PMID: 18256319.
    Citations: 64     Fields:    Translation:AnimalsCells
  20. Cooley J, McDonald B, Accurso FJ, Crouch EC, Remold-O'Donnell E. Patterns of neutrophil serine protease-dependent cleavage of surfactant protein D in inflammatory lung disease. J Leukoc Biol. 2008 Apr; 83(4):946-55. PMID: 18211966.
    Citations: 15     Fields:    Translation:HumansCells
  21. Lutskiy MI, Shcherbina A, Bachli ET, Cooley J, Remold-O'Donnell E. WASP localizes to the membrane skeleton of platelets. Br J Haematol. 2007 Oct; 139(1):98-105. PMID: 17854313.
    Citations: 7     Fields:    Translation:HumansCells
  22. Benarafa C, Priebe GP, Remold-O'Donnell E. The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection. J Exp Med. 2007 Aug 06; 204(8):1901-9. PMID: 17664292.
    Citations: 40     Fields:    Translation:AnimalsCells
  23. Yasumatsu R, Altiok O, Benarafa C, Yasumatsu C, Bingol-Karakoc G, Remold-O'Donnell E, Cataltepe S. SERPINB1 upregulation is associated with in vivo complex formation with neutrophil elastase and cathepsin G in a baboon model of bronchopulmonary dysplasia. . 2006 Oct; 291(4):L619-27. PMID: 16617093.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  24. Benarafa C, Remold-O'Donnell E. The ovalbumin serpins revisited: perspective from the chicken genome of clade B serpin evolution in vertebrates. Proc Natl Acad Sci U S A. 2005 Aug 09; 102(32):11367-72. PMID: 16055559.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  25. Lutskiy MI, Rosen FS, Remold-O'Donnell E. Genotype-proteotype linkage in the Wiskott-Aldrich syndrome. J Immunol. 2005 Jul 15; 175(2):1329-36. PMID: 16002738.
    Citations: 17     Fields:    Translation:HumansCells
  26. Lutskiy MI, Beardsley DS, Rosen FS, Remold-O'Donnell E. Mosaicism of NK cells in a patient with Wiskott-Aldrich syndrome. Blood. 2005 Oct 15; 106(8):2815-7. PMID: 15985539.
    Citations: 10     Fields:    Translation:HumansCells
  27. Woods DE, Cantin A, Cooley J, Kenney DM, Remold-O'Donnell E. Aerosol treatment with MNEI suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection. Pediatr Pulmonol. 2005 Feb; 39(2):141-9. PMID: 15633200.
    Citations: 12     Fields:    Translation:AnimalsCells
  28. Park JY, Shcherbina A, Rosen FS, Prodeus AP, Remold-O'Donnell E. Phenotypic perturbation of B cells in the Wiskott-Aldrich syndrome. Clin Exp Immunol. 2005 Feb; 139(2):297-305. PMID: 15654828.
    Citations: 17     Fields:    Translation:HumansCells
  29. Hirche TO, Crouch EC, Espinola M, Brokelman TJ, Mecham RP, DeSilva N, Cooley J, Remold-O'Donnell E, Belaaouaj A. Neutrophil serine proteinases inactivate surfactant protein D by cleaving within a conserved subregion of the carbohydrate recognition domain. J Biol Chem. 2004 Jun 25; 279(26):27688-98. PMID: 15078883.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  30. Park JY, Kob M, Prodeus AP, Rosen FS, Shcherbina A, Remold-O'Donnell E. Early deficit of lymphocytes in Wiskott-Aldrich syndrome: possible role of WASP in human lymphocyte maturation. Clin Exp Immunol. 2004 Apr; 136(1):104-10. PMID: 15030520.
    Citations: 26     Fields:    Translation:HumansCells
  31. Rubio F, Cooley J, Accurso FJ, Remold-O'Donnell E. Linkage of neutrophil serine proteases and decreased surfactant protein-A (SP-A) levels in inflammatory lung disease. Thorax. 2004 Apr; 59(4):318-23. PMID: 15047952.
    Citations: 18     Fields:    Translation:HumansCells
  32. Thongboonkerd V, Barati MT, McLeish KR, Benarafa C, Remold-O'Donnell E, Zheng S, Rovin BH, Pierce WM, Epstein PN, Klein JB. Alterations in the renal elastin-elastase system in type 1 diabetic nephropathy identified by proteomic analysis. J Am Soc Nephrol. 2004 Mar; 15(3):650-62. PMID: 14978167.
    Citations: 24     Fields:    Translation:AnimalsCells
  33. Shcherbina A, Candotti F, Rosen FS, Remold-O'Donnell E. High incidence of lymphomas in a subgroup of Wiskott-Aldrich syndrome patients. Br J Haematol. 2003 May; 121(3):529-30. PMID: 12716381.
    Citations: 7     Fields:    Translation:HumansCells
  34. Lutskiy MI, Sasahara Y, Kenney DM, Rosen FS, Remold-O'Donnell E. Wiskott-Aldrich syndrome in a female. Blood. 2002 Oct 15; 100(8):2763-8. PMID: 12351383.
    Citations: 6     Fields:    Translation:HumansCells
  35. Benarafa C, Cooley J, Zeng W, Bird PI, Remold-O'Donnell E. Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1). J Biol Chem. 2002 Nov 01; 277(44):42028-33. PMID: 12189154.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  36. Orange JS, Ramesh N, Remold-O'Donnell E, Sasahara Y, Koopman L, Byrne M, Bonilla FA, Rosen FS, Geha RS, Strominger JL. Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses. Proc Natl Acad Sci U S A. 2002 Aug 20; 99(17):11351-6. PMID: 12177428.
    Citations: 86     Fields:    Translation:HumansCells
  37. Jones LN, Lutskiy MI, Cooley J, Kenney DM, Rosen FS, Remold-O'Donnell E. A novel protocol to identify mutations in patients with wiskott-Aldrich syndrome. Blood Cells Mol Dis. 2002 May-Jun; 28(3):392-8. PMID: 12367583.
    Citations: 3     Fields:    Translation:Humans
  38. Lutskiy MI, Jones LN, Rosen FS, Remold-O'Donnell E. An Alu-mediated deletion at Xp11.23 leading to Wiskott-Aldrich syndrome. Hum Genet. 2002 May; 110(5):515-9. PMID: 12073025.
    Citations: 4     Fields:    Translation:HumansCells
  39. Kaiserman D, Knaggs S, Scarff KL, Gillard A, Mirza G, Cadman M, McKeone R, Denny P, Cooley J, Benarafa C, Remold-O'Donnell E, Ragoussis J, Bird PI. Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse. Genomics. 2002 Mar; 79(3):349-62. PMID: 11863365.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  40. Cooley J, Takayama TK, Shapiro SD, Schechter NM, Remold-O'Donnell E. The serpin MNEI inhibits elastase-like and chymotrypsin-like serine proteases through efficient reactions at two active sites. Biochemistry. 2001 Dec 25; 40(51):15762-70. PMID: 11747453.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  41. Shcherbina A, Miki H, Kenney DM, Rosen FS, Takenawa T, Remold-O'Donnell E. WASP and N-WASP in human platelets differ in sensitivity to protease calpain. Blood. 2001 Nov 15; 98(10):2988-91. PMID: 11698281.
    Citations: 8     Fields:    Translation:HumansCells
  42. Loutski M, Remold-O'Donnell E, Roumiantsev AG, Shcherbina A. Regulation of Anti-Tumor Activity Using Monoclonal Antibodies to Alpha-Fetoprotein Receptor and after Immunization with This Protein. Russ J Immunol. 2001 Oct; 6(3):257-264. PMID: 12687225.
    Citations:    Fields:    
  43. Silverman GA, Bird PI, Carrell RW, Church FC, Coughlin PB, Gettins PG, Irving JA, Lomas DA, Luke CJ, Moyer RW, Pemberton PA, Remold-O'Donnell E, Salvesen GS, Travis J, Whisstock JC. The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J Biol Chem. 2001 Sep 07; 276(36):33293-6. PMID: 11435447.
    Citations: 261     Fields:    Translation:HumansAnimalsCells
  44. Fratazzi C, Manjunath N, Arbeit RD, Carini C, Gerken TA, Ardman B, Remold-O'Donnell E, Remold HG. A macrophage invasion mechanism for mycobacteria implicating the extracellular domain of CD43. J Exp Med. 2000 Jul 17; 192(2):183-92. PMID: 10899905.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  45. Zeng W, Remold-O'Donnell E. Human monocyte/neutrophil elastase inhibitor (MNEI) is regulated by PU.1/Spi-1, Sp1, and NF-kappaB. J Cell Biochem. 2000 Jun 12; 78(4):519-32. PMID: 10861849.
    Citations: 6     Fields:    Translation:HumansCells
  46. Shcherbina A, Rosen FS, Remold-O'Donnell E. Reply To matzdorff, kemkes-matthes and pralle Br J Haematol. 2000 Jun; 109(3):674. PMID: 10886227.
    Citations:    Fields:    
  47. Shcherbina A, Rosen FS, Remold-O'Donnell E. WASP levels in platelets and lymphocytes of wiskott-aldrich syndrome patients correlate with cell dysfunction. J Immunol. 1999 Dec 01; 163(11):6314-20. PMID: 10570326.
    Citations: 8     Fields:    Translation:HumansCells
  48. Fabbi M, Geginat J, Tiso M, Ramarli D, Parent D, Bargellesi A, Remold-O'Donnell E. 8B4/20, a private CD43 epitope on developing human thymocytes, is involved in thymocyte maturation. J Immunol. 1999 Dec 01; 163(11):5964-70. PMID: 10570283.
    Citations: 1     Fields:    Translation:HumansCells
  49. Shcherbina A, Rosen FS, Remold-O'Donnell E. Pathological events in platelets of Wiskott-Aldrich syndrome patients. Br J Haematol. 1999 Sep; 106(4):875-83. PMID: 10519987.
    Citations: 11     Fields:    Translation:Humans
  50. Shcherbina A, Bretscher A, Rosen FS, Kenney DM, Remold-O'Donnell E. The cytoskeletal linker protein moesin: decreased levels in Wiskott-Aldrich syndrome platelets and identification of a cleavage pathway in normal platelets. Br J Haematol. 1999 Jul; 106(1):216-23. PMID: 10444190.
    Citations: 2     Fields:    Translation:HumansCells
  51. Shcherbina A, Remold-O'Donnell E. Role of caspase in a subset of human platelet activation responses. Blood. 1999 Jun 15; 93(12):4222-31. PMID: 10361119.
    Citations: 19     Fields:    Translation:HumansCells
  52. Shcherbina A, Bretscher A, Kenney DM, Remold-O'Donnell E. Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain. FEBS Lett. 1999 Jan 22; 443(1):31-6. PMID: 9928947.
    Citations: 27     Fields:    Translation:HumansCells
  53. Rees DD, Rogers RA, Cooley J, Mandle RJ, Kenney DM, Remold-O'Donnell E. Recombinant human Monocyte/Neutrophil elastase inhibitor protects rat lungs against injury from cystic fibrosis airway secretions. Am J Respir Cell Mol Biol. 1999 Jan; 20(1):69-78. PMID: 9870919.
    Citations: 9     Fields:    Translation:HumansAnimals
  54. Cooley J, Mathieu B, Remold-O'Donnell E, Mandle RJ. Production of recombinant human monocyte/neutrophil elastase inhibitor (rM/NEI). Protein Expr Purif. 1998 Oct; 14(1):38-44. PMID: 9758749.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  55. Zeng W, Silverman GA, Remold-O'Donnell E. Structure and sequence of human M/NEI (monocyte/neutrophil elastase inhibitor), an Ov-serpin family gene. Gene. 1998 Jun 15; 213(1-2):179-87. PMID: 9630619.
    Citations: 3     Fields:    Translation:HumansCells
  56. Remold-O'Donnell E, Cooley J, Shcherbina A, Hagemann TL, Kwan SP, Kenney DM, Rosen FS. Variable expression of WASP in B cell lines of Wiskott-Aldrich syndrome patients. J Immunol. 1997 May 01; 158(9):4021-5. PMID: 9126958.
    Citations: 7     Fields:    Translation:HumansCells
  57. Remold-O'Donnell E, Rosen FS, Kenney DM. Defects in Wiskott-Aldrich syndrome blood cells. Blood. 1996 Apr 01; 87(7):2621-31. PMID: 8639877.
    Citations: 16     Fields:    Translation:HumansCells
  58. Packard BZ, Lee SS, Remold-O'Donnell E, Komoriya A. A serpin from human tumor cells with direct lymphoid immunomodulatory activity: mitogenic stimulation of human tumor-infiltrating lymphocytes. Biochim Biophys Acta. 1995 Oct 19; 1269(1):41-50. PMID: 7578269.
    Citations:    Fields:    Translation:HumansCells
  59. Remold-O'Donnell E, Parent D. Specific sensitivity of CD43 to neutrophil elastase. Blood. 1995 Sep 15; 86(6):2395-402. PMID: 7662987.
    Citations: 9     Fields:    Translation:HumansCells
  60. Sugimori T, Cooley J, Hoidal JR, Remold-O'Donnell E. Inhibitory properties of recombinant human monocyte/neutrophil elastase inhibitor. Am J Respir Cell Mol Biol. 1995 Sep; 13(3):314-22. PMID: 7654387.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  61. Evans E, Cooley J, Remold-O'Donnell E. Characterization and chromosomal localization of ELANH2, the gene encoding human monocyte/neutrophil elastase inhibitor. Genomics. 1995 Jul 20; 28(2):235-40. PMID: 8530031.
    Citations: 2     Fields:    Translation:HumansCells
  62. Remold-O'Donnell E, Parent D. Downregulation of neutrophil CD43 by opsonized zymosan. Blood. 1995 Jan 15; 85(2):337-42. PMID: 7811990.
    Citations: 5     Fields:    Translation:HumansCells
  63. Kenney DM, Reid R, Parent DW, Rosen FS, Remold-O'Donnell E. Evidence implicating calpain (Ca(2+)-dependent neutral protease) in the destructive thrombocytopenia of the Wiskott-Aldrich syndrome. Br J Haematol. 1994 Aug; 87(4):773-81. PMID: 7986718.
    Citations:    Fields:    Translation:HumansCells
  64. Remold-O'Donnell E, Parent D. Two proteolytic pathways for down-regulation of the barrier molecule CD43 of human neutrophils. J Immunol. 1994 Apr 01; 152(7):3595-605. PMID: 7511653.
    Citations: 7     Fields:    Translation:HumansCells
  65. Molina IJ, Sancho J, Terhorst C, Rosen FS, Remold-O'Donnell E. T cells of patients with the Wiskott-Aldrich syndrome have a restricted defect in proliferative responses. J Immunol. 1993 Oct 15; 151(8):4383-90. PMID: 8409409.
    Citations: 42     Fields:    Translation:HumansCells
  66. Remold-O'Donnell E. The ovalbumin family of serpin proteins. FEBS Lett. 1993 Jan 04; 315(2):105-8. PMID: 8417965.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  67. Molina IJ, Kenney DM, Rosen FS, Remold-O'Donnell E. T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome. J Exp Med. 1992 Sep 01; 176(3):867-74. PMID: 1512549.
    Citations: 26     Fields:    Translation:HumansCells
  68. Remold-O'Donnell E, Chin J, Alberts M. Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor. Proc Natl Acad Sci U S A. 1992 Jun 15; 89(12):5635-9. PMID: 1376927.
    Citations: 17     Fields:    Translation:HumansCells
  69. Remold-O'Donnell E, Van Brocklyn J, Kenney DM. Effect of platelet calpain on normal T-lymphocyte CD43: hypothesis of events in the Wiskott-Aldrich syndrome. Blood. 1992 Apr 01; 79(7):1754-62. PMID: 1558970.
    Citations: 2     Fields:    Translation:HumansCells
  70. Park JK, Rosenstein YJ, Remold-O'Donnell E, Bierer BE, Rosen FS, Burakoff SJ. Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome. Nature. 1991 Apr 25; 350(6320):706-9. PMID: 2023632.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  71. Remold-O'Donnell E, Rosen FS. Proteolytic fragmentation of sialophorin (CD43). Localization of the activation-inducing site and examination of the role of sialic acid. J Immunol. 1990 Nov 15; 145(10):3372-8. PMID: 2230123.
    Citations: 5     Fields:    Translation:HumansCells
  72. Shelley CS, Remold-O'Donnell E, Rosen FS, Whitehead AS. Structure of the human sialophorin (CD43) gene. Identification of features atypical of genes encoding integral membrane proteins. Biochem J. 1990 Sep 15; 270(3):569-76. PMID: 2241892.
    Citations: 10     Fields:    Translation:HumansCells
  73. Wong RC, Remold-O'Donnell E, Vercelli D, Sancho J, Terhorst C, Rosen F, Geha R, Chatila T. Signal transduction via leukocyte antigen CD43 (sialophorin). Feedback regulation by protein kinase C. J Immunol. 1990 Feb 15; 144(4):1455-60. PMID: 2137493.
    Citations: 15     Fields:    Translation:HumansCells
  74. Remold-O'Donnell E, Rosen FS. Sialophorin (CD43) and the Wiskott-Aldrich syndrome. Immunodefic Rev. 1990; 2(2):151-74. PMID: 2223062.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  75. Nong YH, Remold-O'Donnell E, LeBien TW, Remold HG. A monoclonal antibody to sialophorin (CD43) induces homotypic adhesion and activation of human monocytes. J Exp Med. 1989 Jul 01; 170(1):259-67. PMID: 2787380.
    Citations: 27     Fields:    Translation:HumansCells
  76. Silverman LB, Wong RC, Remold-O'Donnell E, Vercelli D, Sancho J, Terhorst C, Rosen F, Geha R, Chatila T. Mechanism of mononuclear cell activation by an anti-CD43 (sialophorin) agonistic antibody. J Immunol. 1989 Jun 15; 142(12):4194-200. PMID: 2542404.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  77. Shelley CS, Remold-O'Donnell E, Davis AE, Bruns GA, Rosen FS, Carroll MC, Whitehead AS. Molecular characterization of sialophorin (CD43), the lymphocyte surface sialoglycoprotein defective in Wiskott-Aldrich syndrome. Proc Natl Acad Sci U S A. 1989 Apr; 86(8):2819-23. PMID: 2784859.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  78. Remold-O'Donnell E, Nixon JC, Rose RM. Elastase inhibitor. Characterization of the human elastase inhibitor molecule associated with monocytes, macrophages, and neutrophils. J Exp Med. 1989 Mar 01; 169(3):1071-86. PMID: 2926322.
    Citations: 8     Fields:    Translation:HumansCells
  79. Remold-O'Donnell E. Structure and function of macrophage adhesion molecule examined by epitope mapping. J Immunol. 1988 Aug 01; 141(3):905-12. PMID: 2456336.
    Citations: 1     Fields:    Translation:AnimalsCells
  80. Arnaout MA, Remold-O'Donnell E, Pierce MW, Harris P, Tenen DG. Molecular cloning of the alpha subunit of human and guinea pig leukocyte adhesion glycoprotein Mo1: chromosomal localization and homology to the alpha subunits of integrins. Proc Natl Acad Sci U S A. 1988 Apr; 85(8):2776-80. PMID: 2833753.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  81. Remold-O'Donnell E. Regulation of synthesis of macrophage adhesion molecule, a heterodimeric membrane glycoprotein. J Immunol. 1988 Feb 15; 140(4):1244-9. PMID: 3343513.
    Citations: 2     Fields:    Translation:AnimalsCells
  82. Remold-O'Donnell E, Savage B. Characterization of macrophage adhesion molecule. Biochemistry. 1988 Jan 12; 27(1):37-41. PMID: 2964869.
    Citations: 3     Fields:    Translation:AnimalsCells
  83. Remold-O'Donnell E, Savage B. Purification, composition, and structure of macrophage adhesion molecule. Biochemistry. 1988 Jan 12; 27(1):42-5. PMID: 3349044.
    Citations: 2     Fields:    Translation:AnimalsCells
  84. Remold-O'Donnell E, Zimmerman C, Kenney D, Rosen FS. Expression on blood cells of sialophorin, the surface glycoprotein that is defective in Wiskott-Aldrich syndrome. Blood. 1987 Jul; 70(1):104-9. PMID: 2439146.
    Citations: 34     Fields:    Translation:HumansCells
  85. Remold-O'Donnell E, Kenney D, Rosen FS. Biosynthesis of human sialophorins and analysis of the polypeptide core. Biochemistry. 1987 Jun 30; 26(13):3908-13. PMID: 3115291.
    Citations: 14     Fields:    Translation:HumansCells
  86. Mentzer SJ, Remold-O'Donnell E, Crimmins MA, Bierer BE, Rosen FS, Burakoff SJ. Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation. J Exp Med. 1987 May 01; 165(5):1383-92. PMID: 3572301.
    Citations: 35     Fields:    Translation:HumansCells
  87. Pierce MW, Remold-O'Donnell E, Todd RF, Arnaout MA. N-terminal sequence of human leukocyte glycoprotein Mo1: conservation across species and homology to platelet IIb/IIIa. Biochim Biophys Acta. 1986 Dec 12; 874(3):368-71. PMID: 3539202.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  88. Kenney D, Cairns L, Remold-O'Donnell E, Peterson J, Rosen FS, Parkman R. Morphological abnormalities in the lymphocytes of patients with the Wiskott-Aldrich syndrome. Blood. 1986 Dec; 68(6):1329-32. PMID: 3779101.
    Citations: 30     Fields:    Translation:HumansCells
  89. Remold-O'Donnell E, Davis AE, Kenney D, Bhaskar KR, Rosen FS. Purification and chemical composition of gpL115, the human lymphocyte surface sialoglycoprotein that is defective in Wiskott-Aldrich syndrome. J Biol Chem. 1986 Jun 05; 261(16):7526-30. PMID: 3711098.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  90. Remold-O'Donnell E. A fast-acting elastase inhibitor in human monocytes. J Exp Med. 1985 Dec 01; 162(6):2142-55. PMID: 3906019.
    Citations: 5     Fields:    Translation:HumansCells
  91. Parkman R, Remold-O'Donnell E, Cairns L, Rappeport JM, Cowan M, Ammann A, Kenney D, Potter N, Rosen FS. Immune abnormalities in patients lacking a lymphocyte surface glycoprotein. Clin Immunol Immunopathol. 1984 Dec; 33(3):363-70. PMID: 6499285.
    Citations: 2     Fields:    Translation:HumansCells
  92. Remold-O'Donnell E, Kenney DM, Parkman R, Cairns L, Savage B, Rosen FS. Characterization of a human lymphocyte surface sialoglycoprotein that is defective in Wiskott-Aldrich syndrome. J Exp Med. 1984 Jun 01; 159(6):1705-23. PMID: 6547160.
    Citations: 41     Fields:    Translation:HumansCells
  93. Remold-O'Donnell E, Lewandrowski K. Two proteinase inhibitors associated with peritoneal macrophages. J Biol Chem. 1983 Mar 10; 258(5):3251-7. PMID: 6550056.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  94. Parkman R, Remold-O'Donnell E, Kenney DM, Rosen FS. GPL-115 deficiency: a new class of immunodeficiencies. Birth Defects Orig Artic Ser. 1983; 19(3):97-9. PMID: 6606452.
    Citations:    Fields:    Translation:HumansCells
  95. Remold-O'Donnell E. Biosynthesis of gp160, the major trypsin-sensitive surface glycoprotein of macrophages. J Biol Chem. 1982 Jun 10; 257(11):6600-4. PMID: 7076683.
    Citations: 2     Fields:    Translation:AnimalsCells
  96. Remold-O'Donnell E, Lewandrowski K. Decrease of the major surface glycoprotein gp 160 in activated macrophages. Cell Immunol. 1982 Jun; 70(1):85-94. PMID: 7116465.
    Citations: 2     Fields:    Translation:AnimalsCells
  97. Remold-O'Donnell E, Lewandrowski K. Macrophage surface component gp160: sensitivity to plasmin and other proteases. J Immunol. 1982 Apr; 128(4):1541-4. PMID: 6460805.
    Citations: 3     Fields:    Translation:HumansAnimals
  98. Parkman R, Remold-O'Donnell E, Kenney DM, Perrine S, Rosen FS. Surface protein abnormalities in lymphocytes and platelets from patients with Wiskott-Aldrich syndrome. Lancet. 1981 Dec 19-26; 2(8260-61):1387-9. PMID: 6118760.
    Citations: 26     Fields:    Translation:HumansCells
  99. Remold-O'Donnell E. Macrophage component gp160, a major trypsin-sensitive surface glycoprotein. J Exp Med. 1980 Dec 01; 152(6):1699-708. PMID: 7452150.
    Citations: 3     Fields:    Translation:AnimalsCells
  100. Remold-O'Donnell E, Alpert HR. Alteration of hormone-stimulated cyclic AMP synthesis in guinea pig peritoneal macrophages. Cell Immunol. 1979 Jun; 45(1):221-9. PMID: 222485.
    Citations: 4     Fields:    Translation:AnimalsCells
  101. Friedman SA, Remold-O'Donnell E, Piessens WF. Enhanced PGE production by MAF-treated peritoneal exudate macrophages. Cell Immunol. 1979 Jan; 42(1):213-8. PMID: 436150.
    Citations: 6     Fields:    Translation:AnimalsCells
  102. Remold-O'Donnell E. Protein kinase activity associated with the surface of guinea pig macrophages. J Exp Med. 1978 Oct 01; 148(4):1099-104. PMID: 702062.
    Citations: 3     Fields:    Translation:AnimalsCells
  103. Heck LW, Remold-O'Donnell E, Remold HG. DFP-sensitive polypeptides of the guinea pig peritoneal macrophage. Biochem Biophys Res Commun. 1978 Aug 29; 83(4):1576-83. PMID: 697880.
    Citations: 6     Fields:    Translation:AnimalsCells
  104. Remold-O'Donnell E. Purification of plasma membrane of guinea pig peritoneal macrophages. Prep Biochem. 1977; 7(6):441-55. PMID: 605109.
    Citations:    Fields:    Translation:AnimalsCells
  105. Remold-O'Donnell E. Stimulation and desensitization of macrophage adenylate cyclase by prostaglandins and catecholamines. J Biol Chem. 1974 Jun 10; 249(11):361-21. PMID: 4364662.
    Citations: 4     Fields:    Translation:AnimalsCells
  106. Remold-O'Donnell E, Remold HG. The enhancement of macrophage adenylate cyclase by products of activated lymphocytes. J Biol Chem. 1974 Jun 10; 249(11):3622-7. PMID: 4364663.
    Citations: 6     Fields:    Translation:AnimalsCells
  107. Remold-O'Donnell E, Thach RE. A new method for the purification of initiation factor F2 in high yield, and an estimation of stoichiometry in the binding reaction. J Biol Chem. 1970 Nov 10; 245(21):5737-42. PMID: 4919488.
    Citations: 10     Fields:    Translation:Cells
  108. Remold-O'Donnell E, Zillig W. Purification and properties of DNA-dependent RNA-polymerase from Bacillus stearothermophilus. Eur J Biochem. 1969 Jan; 7(3):318-23. PMID: 4894537.
    Citations: 3     Fields:    Translation:Cells
  109. Thach RE, Hershey JW, Kolakofsky D, Dewey KF, Remold-O'Donnell E. Purification and properties of initiation factors F1 and F2. Cold Spring Harb Symp Quant Biol. 1969; 34:277-84. PMID: 4314904.
    Citations: 7     Fields:    Translation:Cells
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