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Hakan Ashina, M.D.

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Biography
education and training
University of Copenhagen, DenmarkMD06/2019Medicine
awards and honors
2021
IHS Early-Career Headache Science Award
2021
LF Talent Prize

Overview

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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ashina H, Christensen RH, Al-Khazali HM, Iljazi A, Tolnai D, Eigenbrodt AK, Larsson HBW, Schytz HW, Lindberg U, Amin FM. White matter hyperintensities and cerebral microbleeds in persistent post-traumatic headache attributed to mild traumatic brain injury: a magnetic resonance imaging study. J Headache Pain. 2023 Feb 24; 24(1):15. PMID: 36823546; PMCID: PMC9951434.
    Citations:    Fields:    Translation:Humans
  2. Al-Khazali HM, Al-Khazali S, Iljazi A, Christensen RH, Ashina S, Lipton RB, Amin FM, Ashina H. Prevalence and clinical features of hemicrania continua in clinic-based studies: A systematic review and meta-analysis. Cephalalgia. 2023 01; 43(1):3331024221131343. PMID: 36588185.
    Citations:    Fields:    Translation:Humans
  3. Gollion C, De Icco R, Dodick DW, Ashina H. The premonitory phase of migraine is due to hypothalamic dysfunction: revisiting the evidence. J Headache Pain. 2022 Dec 13; 23(1):158. PMID: 36514014; PMCID: PMC9745986.
    Citations: 1     Fields:    Translation:Humans
  4. Eigenbrodt AK, Christensen RH, Ashina H, Iljazi A, Christensen CE, Steiner TJ, Lipton RB, Ashina M. Premonitory symptoms in migraine: a systematic review and meta-analysis of observational studies reporting prevalence or relative frequency. J Headache Pain. 2022 Nov 12; 23(1):140. PMID: 36371152; PMCID: PMC9655795.
    Citations: 3     Fields:    Translation:Humans
  5. Ashina H, Iljazi A, Al-Khazali HM, Do TP, Eigenbrodt AK, Larsen EL, Andersen AM, Hansen KJ, Bräuner KB, Chaudhry BA, Christensen CE, Amin FM, Schytz HW. CGRP-induced migraine-like headache in persistent post-traumatic headache attributed to mild traumatic brain injury. J Headache Pain. 2022 Oct 17; 23(1):135. PMID: 36253732; PMCID: PMC9578273.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  6. Chaudhry BA, Do TP, Ashina H, Ashina M, Amin FM. Cluster headache - The worst possible pain on YouTube. Headache. 2022 10; 62(9):1222-1226. PMID: 36056715; PMCID: PMC9826041.
    Citations: 1     Fields:    Translation:Humans
  7. Ashina H, Al-Khazali HM, Iljazi A, Ashina S, Amin FM, Schytz HW. Total tenderness score and pressure pain thresholds in persistent post-traumatic headache attributed to mild traumatic brain injury. J Headache Pain. 2022 Aug 08; 23(1):96. PMID: 35941545; PMCID: PMC9358841.
    Citations:    Fields:    Translation:Humans
  8. Ashina H, Christensen RH, Ashina M. Provoked versus spontaneous migraine attacks: pathophysiological similarities and differences. J Headache Pain. 2022 Jul 23; 23(1):87. PMID: 35870898; PMCID: PMC9308906.
    Citations:    Fields:    Translation:Humans
  9. Cullum CK, Do TP, Ashina M, Bendtsen L, Hugger SS, Iljazi A, Gusatovic J, Snellman J, Lopez-Lopez C, Ashina H, Amin FM. Real-world long-term efficacy and safety of erenumab in adults with chronic migraine: a 52-week, single-center, prospective, observational study. J Headache Pain. 2022 Jun 02; 23(1):61. PMID: 35655137; PMCID: PMC9164431.
    Citations: 3     Fields:    Translation:Humans
  10. Al-Khazali HM, Ashina H, Iljazi A, Al-Sayegh Z, Lipton RB, Ashina M, Ashina S, Schytz HW. Psychiatric Sequelae Following Whiplash Injury: A Systematic Review. Front Psychiatry. 2022; 13:814079. PMID: 35530017; PMCID: PMC9072624.
    Citations:    
  11. Ashina H, Dodick DW. Post-traumatic Headache: Pharmacologic Management and Targeting CGRP Signaling. Curr Neurol Neurosci Rep. 2022 02; 22(2):105-111. PMID: 35138589.
    Citations: 1     Fields:    Translation:Humans
  12. Wiggers A, Ashina H, Hadjikhani N, Sagare A, Zlokovic BV, Lauritzen M, Ashina M. Brain barriers and their potential role in migraine pathophysiology. J Headache Pain. 2022 Jan 26; 23(1):16. PMID: 35081902; PMCID: PMC8903554.
    Citations: 2     Fields:    Translation:Humans
  13. Ashina H, Al-Khazali HM, Iljazi A, Ashina S, Amin FM, Lipton RB, Schytz HW. Psychiatric and cognitive comorbidities of persistent post-traumatic headache attributed to mild traumatic brain injury. J Headache Pain. 2021 Jul 26; 22(1):83. PMID: 34311696.
    Citations: 6     Fields:    Translation:Humans
  14. Eigenbrodt AK, Ashina H, Khan S, Diener HC, Mitsikostas DD, Sinclair AJ, Pozo-Rosich P, Martelletti P, Ducros A, Lantéri-Minet M, Braschinsky M, Del Rio MS, Daniel O, Özge A, Mammadbayli A, Arons M, Skorobogatykh K, Romanenko V, Terwindt GM, Paemeleire K, Sacco S, Reuter U, Lampl C, Schytz HW, Katsarava Z, Steiner TJ, Ashina M. Diagnosis and management of migraine in ten steps. Nat Rev Neurol. 2021 08; 17(8):501-514. PMID: 34145431; PMCID: PMC8321897.
    Citations: 37     Fields:    Translation:Humans
  15. Ashina H, Eigenbrodt AK, Seifert T, Sinclair AJ, Scher AI, Schytz HW, Lee MJ, De Icco R, Finkel AG, Ashina M. Post-traumatic headache attributed to traumatic brain injury: classification, clinical characteristics, and treatment. Lancet Neurol. 2021 06; 20(6):460-469. PMID: 34022171.
    Citations: 18     Fields:    Translation:Humans
  16. Ashina H, Dodick DW. Medication-overuse headache in patients with secondary headache disorders: Need for revision? Headache. 2021 May; 61(5):790-791. PMID: 34105159.
    Citations:    Fields:    Translation:Humans
  17. Ashina M, Buse DC, Ashina H, Pozo-Rosich P, Peres MFP, Lee MJ, Terwindt GM, Halker Singh R, Tassorelli C, Do TP, Mitsikostas DD, Dodick DW. Migraine: integrated approaches to clinical management and emerging treatments. Lancet. 2021 04 17; 397(10283):1505-1518. PMID: 33773612.
    Citations: 27     Fields:    Translation:Humans
  18. Ashina M, Terwindt GM, Al-Karagholi MA, de Boer I, Lee MJ, Hay DL, Schulte LH, Hadjikhani N, Sinclair AJ, Ashina H, Schwedt TJ, Goadsby PJ. Migraine: disease characterisation, biomarkers, and precision medicine. Lancet. 2021 04 17; 397(10283):1496-1504. PMID: 33773610.
    Citations: 41     Fields:    Translation:Humans
  19. Ashina S, Mitsikostas DD, Lee MJ, Yamani N, Wang SJ, Messina R, Ashina H, Buse DC, Pozo-Rosich P, Jensen RH, Diener HC, Lipton RB. Tension-type headache. Nat Rev Dis Primers. 2021 03 25; 7(1):24. PMID: 33767185.
    Citations: 14     Fields:    Translation:Humans
  20. Ashina H, Moskowitz MA. Shared biological foundations of post-traumatic headache and migraine. Headache. 2021 Mar; 61(3):558-559. PMID: 33634463.
    Citations: 3     Fields:    Translation:HumansAnimals
  21. Iljazi A, Ashina H, Zhuang ZA, Lopez Lopez C, Snellman J, Ashina M, Schytz HW. Hypersensitivity to calcitonin gene-related peptide in chronic migraine. Cephalalgia. 2021 05; 41(6):701-710. PMID: 33322922.
    Citations: 5     Fields:    Translation:Humans
  22. Ghanizada H, Iljazi A, Ashina H, Do TP, Al-Karagholi MA, Amin FM, Ashina M. Nocebo response in human models of migraine: A systematic review and meta-analysis of randomized, double-blind, placebo-controlled, two-way crossover trials in migraine without aura and healthy volunteers. Cephalalgia. 2021 01; 41(1):99-111. PMID: 33241720.
    Citations: 6     Fields:    Translation:Humans
  23. Ashina H, Iljazi A, Amin FM, Ashina M, Lipton RB, Schytz HW. Interrelations between migraine-like headache and persistent post-traumatic headache attributed to mild traumatic brain injury: a prospective diary study. J Headache Pain. 2020 Nov 19; 21(1):134. PMID: 33213358; PMCID: PMC7678268.
    Citations: 6     Fields:    Translation:Humans
  24. Ashina H, Iljazi A, Al-Khazali HM, Christensen CE, Amin FM, Ashina M, Schytz HW. Hypersensitivity to Calcitonin Gene-Related Peptide in Post-Traumatic Headache. Ann Neurol. 2020 12; 88(6):1220-1228. PMID: 32959458.
    Citations: 10     Fields:    Translation:Humans
  25. Ashina H, Al-Khazali HM, Iljazi A, Ashina S, Jørgensen NR, Amin FM, Ashina M, Schytz HW. Low plasma levels of calcitonin gene-related peptide in persistent post-traumatic headache attributed to mild traumatic brain injury. Cephalalgia. 2020 10; 40(12):1276-1282. PMID: 32689824.
    Citations: 6     Fields:    Translation:Humans
  26. Iljazi A, Ashina H, Al-Khazali HM, Ashina M, Schytz HW, Ashina S. Post-traumatic stress disorder attributed to traumatic brain injury in children - a systematic review. Brain Inj. 2020 06 06; 34(7):857-863. PMID: 32501734.
    Citations: 2     Fields:    Translation:Humans
  27. Ashina H, Iljazi A, Al-Khazali HM, Eigenbrodt AK, Larsen EL, Andersen AM, Hansen KJ, Bräuner KB, Mørch-Jessen T, Chaudhry B, Antic S, Christensen CE, Ashina M, Amin FM, Schytz HW. Efficacy, tolerability, and safety of erenumab for the preventive treatment of persistent post-traumatic headache attributed to mild traumatic brain injury: an open-label study. J Headache Pain. 2020 Jun 03; 21(1):62. PMID: 32493206; PMCID: PMC7271543.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  28. Hvedstrup J, Amin FM, Hougaard A, Ashina H, Christensen CE, Larsson HBW, Ashina M, Schytz HW. Volume of the rectus capitis posterior minor muscle in migraine patients: a cross-sectional structural MRI study. J Headache Pain. 2020 May 27; 21(1):57. PMID: 32460751; PMCID: PMC7254728.
    Citations: 2     Fields:    Translation:Humans
  29. Pellesi L, Do TP, Ashina H, Ashina M, Burstein R. Dual Therapy With Anti-CGRP Monoclonal Antibodies and Botulinum Toxin for Migraine Prevention: Is There a Rationale? Headache. 2020 06; 60(6):1056-1065. PMID: 32437038.
    Citations: 16     Fields:    Translation:HumansAnimals
  30. Iljazi A, Ashina H, Al-Khazali HM, Lipton RB, Ashina M, Schytz HW, Ashina S. Post-Traumatic Stress Disorder After Traumatic Brain Injury-A Systematic Review and Meta-Analysis. Neurol Sci. 2020 Oct; 41(10):2737-2746. PMID: 32415640.
    Citations: 10     Fields:    Translation:Humans
  31. Al-Khazali HM, Ashina H, Iljazi A, Lipton RB, Ashina M, Ashina S, Schytz HW. Neck pain and headache after whiplash injury: a systematic review and meta-analysis. Pain. 2020 05; 161(5):880-888. PMID: 31977938.
    Citations: 3     Fields:    Translation:Humans
  32. Iljazi A, Ashina H, Lipton RB, Chaudhry B, Al-Khazali HM, Naples JG, Schytz HW, Vukovic Cvetkovic V, Burstein R, Ashina S. Dizziness and vertigo during the prodromal phase and headache phase of migraine: A systematic review and meta-analysis. Cephalalgia. 2020 09; 40(10):1095-1103. PMID: 32349538.
    Citations: 5     Fields:    Translation:Humans
  33. Andersen AM, Ashina H, Iljazi A, Al-Khazali HM, Chaudhry B, Ashina M, Ashina S, Schytz HW. Risk Factors for the Development of Post-Traumatic Headache Attributed to Traumatic Brain Injury: A Systematic Review. Headache. 2020 06; 60(6):1066-1075. PMID: 32320055.
    Citations: 3     Fields:    Translation:Humans
  34. Ashina H, Iljazi A, Al-Khazali HM, Ashina S, Jensen RH, Amin FM, Ashina M, Schytz HW. Persistent post-traumatic headache attributed to mild traumatic brain injury: Deep phenotyping and treatment patterns. Cephalalgia. 2020 05; 40(6):554-564. PMID: 32102546.
    Citations: 22     Fields:    Translation:Humans
  35. Larsen EL, Ashina H, Iljazi A, Al-Khazali HM, Seem K, Ashina M, Ashina S, Schytz HW. Acute and preventive pharmacological treatment of post-traumatic headache: a systematic review. J Headache Pain. 2019 Oct 21; 20(1):98. PMID: 31638888; PMCID: PMC6802300.
    Citations: 13     Fields:    Translation:Humans
  36. Ashina H, Porreca F, Anderson T, Amin FM, Ashina M, Schytz HW, Dodick DW. Post-traumatic headache: epidemiology and pathophysiological insights. Nat Rev Neurol. 2019 10; 15(10):607-617. PMID: 31527806.
    Citations: 43     Fields:    Translation:HumansAnimals
  37. Ashina H, Schytz HW, Ashina M. CGRP in Human Models of Migraine. Handb Exp Pharmacol. 2019; 255:109-120. PMID: 29896653.
    Citations: 13     Fields:    Translation:Humans
  38. Ashina H, Guo S, Vollesen ALH, Ashina M. PACAP38 in human models of primary headaches. J Headache Pain. 2017 Nov 23; 18(1):110. PMID: 29453754; PMCID: PMC5815979.
    Citations: 6     Fields:    Translation:Humans
  39. Ashina H, Newman L, Ashina S. Calcitonin gene-related peptide antagonism and cluster headache: an emerging new treatment. Neurol Sci. 2017 Dec; 38(12):2089-2093. PMID: 28856479.
    Citations: 6     Fields:    Translation:HumansAnimals
  40. Ashina H, Li XQ, Olsen EM, Skovgaard AM, Larsen M, Munch IC. Association of Maternal Smoking During Pregnancy and Birth Weight With Retinal Nerve Fiber Layer Thickness in Children Aged 11 or 12 Years: The Copenhagen Child Cohort 2000 Eye Study. JAMA Ophthalmol. 2017 04 01; 135(4):331-337. PMID: 28253396.
    Citations: 7     Fields:    Translation:HumansCells
  41. Ashina H, Schytz HW, Ashina M. CGRP in human models of primary headaches. Cephalalgia. 2018 02; 38(2):353-360. PMID: 27940880.
    Citations: 12     Fields:    Translation:Humans
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© 2023 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.