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Sébastien Levesque, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Levesque S, Mayorga D, Fiset JP, Goupil C, Duringer A, Loiselle A, Bouchard E, Agudelo D, Doyon Y. Marker-free co-selection for successive rounds of prime editing in human cells. Nat Commun. 2022 10 07; 13(1):5909. PMID: 36207338; PMCID: PMC9546848.
    Citations: 1     Fields:    Translation:Humans
  2. Denormandie P, Simon T, Cayla G, Steg PG, Montalescot G, Durand-Zaleski I, le Bras A, le Breton H, Valy Y, Schiele F, Cuisset T, Vanzetto G, Levesque S, Goube P, Nallet O, Angoulvant D, Roubille F, Charles Nelson A, Chatellier G, Danchin N, Puymirat E. Compared Outcomes of ST-Segment-Elevation Myocardial Infarction Patients With Multivessel Disease Treated With Primary Percutaneous Coronary Intervention and Preserved Fractional Flow Reserve of Nonculprit Lesions Treated Conservatively and of Those With Low Fractional Flow Reserve Managed Invasively: Insights From the FLOWER-MI Trial. Circ Cardiovasc Interv. 2021 11; 14(11):e011314. PMID: 34420366.
    Citations: 3     Fields:    Translation:Humans
  3. De Luca G, Debel N, Cercek M, Jensen LO, Vavlukis M, Calmac L, Johnson T, Ferrer GR, Ganyukov V, Wojakowski W, Kinnaird T, von Birgelen C, Cottin Y, IJsselmuiden A, Tuccillo B, Versaci F, Royaards KJ, Berg JT, Laine M, Dirksen M, Siviglia M, Casella G, Kala P, Díez Gil JL, Banning A, Becerra V, De Simone C, Santucci A, Carrillo X, Scoccia A, Amoroso G, Van't Hof AW, Kovarnik T, Tsigkas G, Mehilli J, Gabrielli G, Rios XF, Bakraceski N, Levesque S, Cirrincione G, Guiducci V, Kidawa M, Spedicato L, Marinucci L, Ludman P, Zilio F, Galasso G, Fabris E, Menichelli M, Garcia-Touchard A, Manzo S, Caiazzo G, Moreu J, Forés JS, Donazzan L, Vignali L, Teles R, Benit E, Agostoni P, Ojeda FB, Lehtola H, Camacho-Freiere S, Kraaijeveld A, Antti Y, Boccalatte M, Deharo P, Martínez-Luengas IL, Scheller B, Varytimiadi E, Moreno R, Uccello G, Faurie B, Gutierrez Barrios A, Milewski M, Bruwiere E, Smits P, Wilbert B, Di Uccio FS, Parodi G, Kedhi E, Verdoia M. Impact of SARS-CoV-2 positivity on clinical outcome among STEMI patients undergoing mechanical reperfusion: Insights from the ISACS STEMI COVID 19 registry. Atherosclerosis. 2021 09; 332:48-54. PMID: 34391035; PMCID: PMC8294603.
    Citations: 10     Fields:    Translation:HumansCells
  4. De Luca G, Cercek M, Okkels Jensen L, Bushljetikj O, Calmac L, Johnson T, Gracida Blancas M, Ganyukov V, Wojakowski W, von Birgelen C, IJsselmuiden A, Tuccillo B, Versaci F, Ten Berg J, Laine M, Berkout T, Casella G, Kala P, López Ledesma B, Becerra V, Padalino R, Santucci A, Carrillo X, Scoccia A, Amoroso G, Lux A, Kovarnik T, Davlouros P, Gabrielli G, Flores Rios X, Bakraceski N, Levesque S, Guiducci V, Kidawa M, Marinucci L, Zilio F, Galasso G, Fabris E, Menichelli M, Manzo S, Caiazzo G, Moreu J, Sanchis Forés J, Donazzan L, Vignali L, Teles R, Agostoni P, Bosa Ojeda F, Lehtola H, Camacho-Freiere S, Kraaijeveld A, Antti Y, Visconti G, Lozano Martínez-Luengas I, Scheller B, Alexopulos D, Moreno R, Kedhi E, Uccello G, Faurie B, Gutierrez Barrios A, Scotto Di Uccio F, Wilbert B, Cortese G, Dirksen MT, Parodi G, Verdoia M. Impact of renin-angiotensin system inhibitors on mortality during the COVID Pandemic among STEMI patients undergoing mechanical reperfusion: Insight from an international STEMI registry. Biomed Pharmacother. 2021 Jun; 138:111469. PMID: 33740523; PMCID: PMC7962982.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  5. De Luca G, Cercek M, Jensen LO, Vavlukis M, Calmac L, Johnson T, Roura I Ferrer G, Ganyukov V, Wojakowski W, von Birgelen C, Versaci F, Ten Berg J, Laine M, Dirksen M, Casella G, Kala P, Díez Gil JL, Becerra V, De Simone C, Carrill X, Scoccia A, Lux A, Kovarnik T, Davlouros P, Gabrielli G, Flores Rios X, Bakraceski N, Levesque S, Guiducci V, Kidawa M, Marinucci L, Zilio F, Galasso G, Fabris E, Menichelli M, Manzo S, Caiazzo G, Moreu J, Sanchis Forés J, Donazzan L, Vignali L, Teles R, Bosa Ojeda F, Lehtola H, Camacho-Freiere S, Kraaijeveld A, Antti Y, Boccalatte M, Martínez-Luengas IL, Scheller B, Alexopoulos D, Uccello G, Faurie B, Gutierrez Barrios A, Wilbert B, Cortese G, Moreno R, Parodi G, Kedhi E, Verdoia M. Impact of COVID-19 pandemic and diabetes on mechanical reperfusion in patients with STEMI: insights from the ISACS STEMI COVID 19 Registry. Cardiovasc Diabetol. 2020 12 18; 19(1):215. PMID: 33339541; PMCID: PMC7747477.
    Citations: 15     Fields:    Translation:Humans
  6. De Luca G, Verdoia M, Cercek M, Jensen LO, Vavlukis M, Calmac L, Johnson T, Ferrer GR, Ganyukov V, Wojakowski W, Kinnaird T, van Birgelen C, Cottin Y, IJsselmuiden A, Tuccillo B, Versaci F, Royaards KJ, Berg JT, Laine M, Dirksen M, Siviglia M, Casella G, Kala P, Díez Gil JL, Banning A, Becerra V, De Simone C, Santucci A, Carrillo X, Scoccia A, Amoroso G, Lux A, Kovarnik T, Davlouros P, Mehilli J, Gabrielli G, Rios XF, Bakraceski N, Levesque S, Cirrincione G, Guiducci V, Kidawa M, Spedicato L, Marinucci L, Ludman P, Zilio F, Galasso G, Fabris E, Menichelli M, Garcia-Touchard A, Manzo S, Caiazzo G, Moreu J, Forés JS, Donazzan L, Vignali L, Teles R, Benit E, Agostoni P, Bosa Ojeda F, Lehtola H, Camacho-Freiere S, Kraaijeveld A, Antti Y, Boccalatte M, Deharo P, Martínez-Luengas IL, Scheller B, Alexopoulos D, Moreno R, Kedhi E, Uccello G, Faurie B, Gutierrez Barrios A, Di Uccio FS, Wilbert B, Smits P, Cortese G, Parodi G, Dudek D. Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI. J Am Coll Cardiol. 2020 11 17; 76(20):2321-2330. PMID: 33183506; PMCID: PMC7834750.
    Citations: 82     Fields:    Translation:HumansPHPublic Health
  7. Philippe C, Levesque S, Dion MB, Tremblay DM, Horvath P, Lüth N, Cambillau C, Franz C, Neve H, Fremaux C, Heller KJ, Moineau S. Novel Genus of Phages Infecting Streptococcus thermophilus: Genomic and Morphological Characterization. Appl Environ Microbiol. 2020 06 17; 86(13). PMID: 32303549; PMCID: PMC7301855.
    Citations: 12     Fields:    Translation:Cells
  8. Levesque S, Gaufroy A, Gamet A, Motreff P, Christiaens LP. Unpredictable Midterm Coronary Damage after Knuckle-reverse CART: Should We Be More Careful? Korean Circ J. 2020 Sep; 50(9):839-842. PMID: 32725986; PMCID: PMC7440997.
    Citations:    
  9. Levesque S, Agudelo D, Doyon Y. Rewired Cas9s with Minimal Sequence Constraints. Trends Pharmacol Sci. 2020 07; 41(7):429-431. PMID: 32416935.
    Citations:    Fields:    Translation:Cells
  10. Agudelo D, Carter S, Velimirovic M, Duringer A, Rivest JF, Levesque S, Loehr J, Mouchiroud M, Cyr D, Waters PJ, Laplante M, Moineau S, Goulet A, Doyon Y. Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9. Genome Res. 2020 01; 30(1):107-117. PMID: 31900288; PMCID: PMC6961573.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  11. Levesque S, Gamet A, Lattuca B, Lemoine J, Bressollette E, Avran A, Motreff P, Boudou N, Faurie B, Christiaens L. Post-stEnting assessment of Re-endothelialization with optical Frequency domain imaging aftEr Chronic Total Occlusion procedure: The PERFE-CTO Study Design and Rationale. Cardiovasc Revasc Med. 2020 06; 21(6):760-764. PMID: 31679911.
    Citations: 1     Fields:    Translation:Humans
  12. Fuchsbauer O, Swuec P, Zimberger C, Amigues B, Levesque S, Agudelo D, Duringer A, Chaves-Sanjuan A, Spinelli S, Rousseau GM, Velimirovic M, Bolognesi M, Roussel A, Cambillau C, Moineau S, Doyon Y, Goulet A. Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6. Mol Cell. 2019 12 19; 76(6):922-937.e7. PMID: 31604602.
    Citations: 20     Fields:    Translation:HumansCells
  13. Levesque S, de Melo AG, Labrie SJ, Moineau S. Mobilome of Brevibacterium aurantiacum Sheds Light on Its Genetic Diversity and Its Adaptation to Smear-Ripened Cheeses. Front Microbiol. 2019; 10:1270. PMID: 31244798; PMCID: PMC6579920.
    Citations: 4     
  14. Lordet V, Lesbordes M, Garcia R, Varroud-Vial N, Ingrand P, Christiaens L, Levesque S. Prevalence and outcome of patients referred for chest pain with high-sensitivity troponin elevation and no diagnosis at discharge. Clin Cardiol. 2018 Jul; 41(7):953-958. PMID: 29802723; PMCID: PMC6489751.
    Citations: 1     Fields:    Translation:Humans
  15. Brunet MA, Levesque SA, Hunting DJ, Cohen AA, Roucou X. Recognition of the polycistronic nature of human genes is critical to understanding the genotype-phenotype relationship. Genome Res. 2018 05; 28(5):609-624. PMID: 29626081; PMCID: PMC5932603.
    Citations: 28     Fields:    Translation:HumansCells
  16. Levesque S, Moineau S. A stockpile of antiviral defences. Nature. 2018 04; 556(7701):318-319. PMID: 29662135.
    Citations: 1     Fields:    Translation:PHPublic Health
  17. de Winter RJ, Katagiri Y, Asano T, Milewski KP, Lurz P, Buszman P, Jessurun GAJ, Koch KT, Troquay RPT, Hamer BJB, Ophuis TO, Wöhrle J, Wyderka R, Cayla G, Hofma SH, Levesque S, Zurakowski A, Fischer D, Kosmider M, Goube P, Arkenbout EK, Noutsias M, Ferrari MW, Onuma Y, Wijns W, Serruys PW. A sirolimus-eluting bioabsorbable polymer-coated stent (MiStent) versus an everolimus-eluting durable polymer stent (Xience) after percutaneous coronary intervention (DESSOLVE III): a randomised, single-blind, multicentre, non-inferiority, phase 3 trial. Lancet. 2018 02 03; 391(10119):431-440. PMID: 29203070.
    Citations: 22     Fields:    Translation:HumansCTClinical Trials
  18. de Melo AG, Levesque S, Moineau S. Phages as friends and enemies in food processing. Curr Opin Biotechnol. 2018 02; 49:185-190. PMID: 28987913.
    Citations: 23     Fields:    Translation:CellsPHPublic Health
  19. Amabile N, Trouillet C, Meneveau N, Tissot CM, Belle L, Combaret N, Range G, Pansieri M, Delaunay R, Levesque S, Lhermusier T, Derimay F, Motreff P, Caussin C, Souteyrand G. Mechanical abnormalities associated with first- and second-generation drug-eluting stent thrombosis analyzed by optical coherence tomography in the national PESTO French registry. Int J Cardiol. 2017 Jan 15; 227:161-165. PMID: 27863292.
    Citations: 3     Fields:    Translation:Humans
  20. Levesque S, Barber-Chamoux N, Gellen B. Percutaneous extraction of a fractured and protruding ostial stent fragment using a vascular retrieval forceps device. Coron Artery Dis. 2016 May; 27(3):250-1. PMID: 26584053.
    Citations:    Fields:    Translation:Humans
  21. La Piana R, Tran LT, Guerrero K, Brais B, Levesque S, Sébire G, Riou E, Bernard G. Spastic paraparesis and marked improvement of leukoencephalopathy in Aicardi-Goutières syndrome. Neuropediatrics. 2014 Dec; 45(6):406-10. PMID: 25343331.
    Citations: 2     Fields:    Translation:Humans
  22. Levesque S, Souteyrand G, Motreff P. Control of iatrogenic coronary dissection with optical coherence tomography. Arch Cardiovasc Dis. 2014 Aug-Sep; 107(8-9):479-81. PMID: 23791581.
    Citations:    Fields:    Translation:Humans
  23. Motreff P, Levesque S, Souteyrand G, Sarry L, Ouchchane L, Citron B, Cassagnes J, Lusson JR. High-resolution coronary imaging by optical coherence tomography: Feasibility, pitfalls and artefact analysis. Arch Cardiovasc Dis. 2010 Apr; 103(4):215-26. PMID: 20656632.
    Citations: 2     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.