Harvard Catalyst Profiles

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Frank J.P. Hoebers, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Sahin O, Wahid KA, Taku N, He R, Naser MA, Mohamed ASR, Mäkitie A, Kann BH, Kaski K, Sahlsten J, Jaskari J, Amit M, Chen MM, Chronowski GM, Diaz EM, Garden AS, Goepfert RP, Guenette JP, Gunn GB, Hirvonen J, Hoebers F, Guha-Thakurta N, Johnson J, Kaya D, Khanpara SD, Nyman K, Lai SY, Lango M, Learned KO, Lee A, Lewis CM, Maniakas A, Moreno AC, Myers JN, Phan J, Pytynia KB, Rosenthal DI, Sandulache V, Schellingerhout D, Shah SJ, Sikora AG, Wintermark M, Fuller CD. Multi-Specialty Expert Physician Identification of Extranodal Extension in Computed Tomography Scans of Oropharyngeal Cancer Patients: Prospective Blinded Human Inter-Observer Performance Evaluation. medRxiv. 2023 Feb 26. PMID: 36865096; PMCID: PMC9980252.
  2. Samant P, Ruysscher D, Hoebers F, Canters R, Hall E, Nutting C, Maughan T, Van den Heuvel F. Machine learning for normal tissue complication probability prediction: Predictive power with versatility and easy implementation. Clin Transl Radiat Oncol. 2023 Mar; 39:100595. PMID: 36880063; PMCID: PMC9984444.
  3. Willemsen ACH, Pilz W, Hoeben A, Hoebers FJP, Schols AMWJ, Baijens LWJ. Oropharyngeal dysphagia and cachexia: Intertwined in head and neck cancer. Head Neck. 2023 04; 45(4):783-797. PMID: 36583567.
    Citations:    Fields:    
  4. Leeuwenberg AM, Reitsma JB, Van den Bosch LGLJ, Hoogland J, van der Schaaf A, Hoebers FJP, Wijers OB, Langendijk JA, Moons KGM, Schuit E. The relation between prediction model performance measures and patient selection outcomes for proton therapy in head and neck cancer. Radiother Oncol. 2023 02; 179:109449. PMID: 36566991.
    Citations:    Fields:    Translation:Humans
  5. Zeng PYF, Cecchini MJ, Barrett JW, Shammas-Toma M, De Cecco L, Serafini MS, Cavalieri S, Licitra L, Hoebers F, Brakenhoff RH, Leemans CR, Scheckenbach K, Poli T, Wang X, Liu X, Laxague F, Prisman E, Poh C, Bose P, Dort JC, Shaikh MH, Ryan SEB, Dawson A, Khan MI, Howlett CJ, Stecho W, Plantinga P, Daniela da Silva S, Hier M, Khan H, MacNeil D, Mendez A, Yoo J, Fung K, Lang P, Winquist E, Palma DA, Ziai H, Amelio AL, Li SS, Boutros PC, Mymryk JS, Nichols AC. Immune-based classification of HPV-associated oropharyngeal cancer with implications for biomarker-driven treatment de-intensification. EBioMedicine. 2022 Dec; 86:104373. PMID: 36442320; PMCID: PMC9706534.
    Citations:    Fields:    Translation:HumansCells
  6. Taasti VT, Hazelaar C, Vaassen F, Vaniqui A, Verhoeven K, Hoebers F, van Elmpt W, Canters R, Unipan M. Clinical implementation and validation of an automated adaptive workflow for proton therapy. Phys Imaging Radiat Oncol. 2022 Oct; 24:59-64. PMID: 36193239; PMCID: PMC9525894.
  7. Kalendralis P, Sloep M, Moni George N, Snel J, Veugen J, Hoebers F, Wesseling F, Unipan M, Veening M, Langendijk JA, Dekker A, van Soest J, Fijten R. Independent validation of a dysphagia dose response model for the selection of head and neck cancer patients to proton therapy. Phys Imaging Radiat Oncol. 2022 Oct; 24:47-52. PMID: 36158240; PMCID: PMC9493379.
    Citations: 1     
  8. de Roest RH, van der Heijden M, Wesseling FWR, de Ruiter EJ, Heymans MW, Terhaard C, Vergeer MR, Buter J, Devriese LA, de Boer JP, Navran A, Hoeben A, Vens C, van den Brekel M, Brakenhoff RH, Leemans CR, Hoebers F. Disease outcome and associated factors after definitive platinum based chemoradiotherapy for advanced stage HPV-negative head and neck cancer. Radiother Oncol. 2022 10; 175:112-121. PMID: 35973619.
    Citations:    Fields:    Translation:Humans
  9. Hoebers F, Yu E, O'Sullivan B, Postma AA, Palm WM, Bartlett E, Lee J, Stock S, Koyfman S, Su J, Xu W, Huang SH. Augmenting inter-rater concordance of radiologic extranodal extension in HPV-positive oropharyngeal carcinoma: A multicenter study. Head Neck. 2022 11; 44(11):2361-2369. PMID: 35766141.
    Citations: 1     Fields:    Translation:Humans
  10. Straetmans JMJAA, Stuut M, Lacko M, Hoebers F, Speel EM, Kremer B. Additional parameters to improve the prognostic value of the 8th edition of the UICC classification for human papillomavirus-related oropharyngeal tumors. Head Neck. 2022 08; 44(8):1799-1815. PMID: 35579041; PMCID: PMC9544856.
    Citations: 2     Fields:    Translation:HumansCells
  11. de Ruiter EJ, Bisheshar SK, de Roest RH, Wesseling FWR, Hoebers FJP, van den Hout MFCM, Leemans CR, Brakenhoff RH, de Bree R, Terhaard CHJ, Willems SM. Assessing the prognostic value of tumor-infiltrating CD57+ cells in advanced stage head and neck cancer using QuPath digital image analysis. Virchows Arch. 2022 Aug; 481(2):223-231. PMID: 35451620; PMCID: PMC9343309.
    Citations: 1     Fields:    Translation:HumansCells
  12. Buurman DJM, Willemsen ACH, Speksnijder CM, Baijens LWJ, Hoeben A, Hoebers FJP, Kessler P, Schols AMWJ. Tooth extractions prior to chemoradiation or bioradiation are associated with weight loss during treatment for locally advanced oropharyngeal cancer. Support Care Cancer. 2022 Jun; 30(6):5329-5338. PMID: 35278135; PMCID: PMC9046292.
    Citations:    Fields:    Translation:Humans
  13. Di Perri D, Hofstede D, Postma A, Zegers CML, In't Ven L, Hoebers F, van Elmpt W, Verheesen L, Beurskens H, Troost EGC, Compter I, Eekers DBP. Development of explanatory movies for the delineation of new organs at risk in neuro-oncology. Clin Transl Radiat Oncol. 2022 Mar; 33:112-114. PMID: 35243021; PMCID: PMC8857542.
  14. Schoonbeek RC, de Jel DVC, van Dijk BAC, Willems SM, Bloemena E, Hoebers FJP, van Meerten E, Verbist BM, Smeele LE, Halmos GB, Merkx MAW, Siesling S, De Bree R, Takes RP. Response to "Head and neck cancer diagnoses and faster treatment initiation during COVID-19: Correspondence". Radiother Oncol. 2022 04; 169:146-147. PMID: 35101464; PMCID: PMC8800124.
    Citations:    Fields:    
  15. Schoonbeek RC, de Jel DVC, van Dijk BAC, Willems SM, Bloemena E, Hoebers FJP, van Meerten E, Verbist BM, Smeele LE, Halmos GB, Merkx MAW, Siesling S, De Bree R, Takes RP. Fewer head and neck cancer diagnoses and faster treatment initiation during COVID-19 in 2020: A nationwide population-based analysis. Radiother Oncol. 2022 02; 167:42-48. PMID: 34915063; PMCID: PMC8667560.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  16. Tambas M, van der Laan HP, Steenbakkers RJHM, Doyen J, Timmermann B, Orlandi E, Hoyer M, Haustermans K, Georg P, Burnet NG, Gregoire V, Calugaru V, Troost EGC, Hoebers F, Calvo FA, Widder J, Eberle F, van Vulpen M, Maingon P, Skóra T, Weber DC, Bergfeldt K, Kubes J, Langendijk JA. Current practice in proton therapy delivery in adult cancer patients across Europe. Radiother Oncol. 2022 02; 167:7-13. PMID: 34902370.
    Citations: 6     Fields:    Translation:Humans
  17. Willemsen ACH, Kok A, Baijens LWJ, de Boer JP, de Bree R, Devriese LA, Driessen CML, van Herpen CML, Hoebers FJP, Kaanders JHAM, Karsten RT, van Kuijk SMJ, Lalisang RI, Navran A, Pereboom SR, Schols AMWJ, Terhaard CHJ, Hoeben A. Development and external validation of a prediction model for tube feeding dependency for at least four weeks during chemoradiotherapy for head and neck cancer. Clin Nutr. 2022 01; 41(1):177-185. PMID: 34883306.
    Citations:    Fields:    Translation:Humans
  18. Cavalieri S, Serafini MS, Carenzo A, Canevari S, Brakenhoff RH, Leemans CR, Nauta IH, Hoebers F, van den Hout MFCM, Scheckenbach K, Hoffmann TK, Ardighieri L, Poli T, Quattrone P, Locati LD, Licitra L, De Cecco L. Clinical Validity of a Prognostic Gene Expression Cluster-Based Model in Human Papillomavirus-Positive Oropharyngeal Carcinoma. JCO Precis Oncol. 2021; 5. PMID: 34738049; PMCID: PMC8563075.
    Citations: 2     Fields:    Translation:HumansCells
  19. Nauta IH, Klausch T, van de Ven PM, Hoebers FJP, Licitra L, Poli T, Scheckenbach K, Brakenhoff RH, Berkhof J, René Leemans C. The important role of cisplatin in the treatment of HPV-positive oropharyngeal cancer assessed by real-world data analysis. Oral Oncol. 2021 10; 121:105454. PMID: 34311328.
    Citations: 1     Fields:    Translation:Humans
  20. van der Heide MFJ, de Jel DVC, Hoeijmakers F, Hoebers FJP, de Boer JP, Hamming-Vrieze O, Wouters MWJM, Smeele LE. Defining High-Quality Integrated Head and Neck Cancer Care Through a Composite Outcome Measure: Textbook Outcome. Laryngoscope. 2022 01; 132(1):78-87. PMID: 34216399.
    Citations:    Fields:    Translation:Humans
  21. Keek SA, Wesseling FWR, Woodruff HC, van Timmeren JE, Nauta IH, Hoffmann TK, Cavalieri S, Calareso G, Primakov S, Leijenaar RTH, Licitra L, Ravanelli M, Scheckenbach K, Poli T, Lanfranco D, Vergeer MR, Leemans CR, Brakenhoff RH, Hoebers FJP, Lambin P. A Prospectively Validated Prognostic Model for Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck Based on Radiomics of Computed Tomography Images. Cancers (Basel). 2021 Jun 29; 13(13). PMID: 34210048; PMCID: PMC8269129.
    Citations: 4     
  22. Lin A, Chang JHC, Grover RS, Hoebers FJP, Parvathaneni U, Patel SH, Thariat J, Thomson DJ, Langendijk JA, Frank SJ. PTCOG Head and Neck Subcommittee Consensus Guidelines on Particle Therapy for the Management of Head and Neck Tumors. Int J Part Ther. 2021; 8(1):84-94. PMID: 34285938; PMCID: PMC8270078.
    Citations: 1     
  23. Langendijk JA, Hoebers FJP, de Jong MA, Doornaert P, Terhaard CHJ, Steenbakkers RJHM, Hamming-Vrieze O, van de Kamer JB, Verbakel WFAR, Keskin-Cambay F, Reitsma JB, van der Schaaf A, Boersma LJ, Schuit E. National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer. Int J Part Ther. 2021; 8(1):354-365. PMID: 34285961; PMCID: PMC8270079.
    Citations: 7     
  24. Simon SR, Pilz W, Hoebers FJP, Leeters IPM, Schols AMWJ, Willemsen ACH, Winkens B, Baijens LWJ. Malnutrition screening in head and neck cancer patients with oropharyngeal dysphagia. Clin Nutr ESPEN. 2021 08; 44:348-355. PMID: 34330489.
    Citations: 3     Fields:    Translation:Humans
  25. de Vos-Geelen J, Geurts SME, Nieuwenhuijzen GAP, Voncken FEM, Bogers JA, Braam PM, Muijs CT, de Jong MA, Kasperts N, Rozema T, Blom GJ, Bouwense SAW, Valkenburg-van Iersel LBJ, Jeene PM, Hoebers FJP, Tjan-Heijnen VCG. Patterns of recurrence following definitive chemoradiation for patients with proximal esophageal cancer. Eur J Surg Oncol. 2021 08; 47(8):2016-2022. PMID: 33583629.
    Citations: 1     Fields:    Translation:Humans
  26. Van den Bosch L, van der Schaaf A, van der Laan HP, Hoebers FJP, Wijers OB, van den Hoek JGM, Moons KGM, Reitsma JB, Steenbakkers RJHM, Schuit E, Langendijk JA. Comprehensive toxicity risk profiling in radiation therapy for head and neck cancer: A new concept for individually optimised treatment. Radiother Oncol. 2021 04; 157:147-154. PMID: 33545258.
    Citations: 12     Fields:    Translation:HumansPHPublic Health
  27. Willemsen ACH, Degens JHRJ, Baijens LWJ, Dingemans AC, Hoeben A, Hoebers FJP, De Ruysscher DKM, Schols AMWJ. Early Loss of Fat Mass During Chemoradiotherapy Predicts Overall Survival in Locally Advanced Squamous Cell Carcinoma of the Lung, but Not in Locally Advanced Squamous Cell Carcinoma of the Head and Neck. Front Nutr. 2020; 7:600612. PMID: 33324671; PMCID: PMC7726186.
    Citations: 6     
  28. Zhai TT, Wesseling F, Langendijk JA, Shi Z, Kalendralis P, van Dijk LV, Hoebers F, Steenbakkers RJHM, Dekker A, Wee L, Sijtsema NM. External validation of nodal failure prediction models including radiomics in head and neck cancer. Oral Oncol. 2021 01; 112:105083. PMID: 33189001.
    Citations: 6     Fields:    Translation:Humans
  29. Sanduleanu S, Jochems A, Upadhaya T, Even AJG, Leijenaar RTH, Dankers FJWM, Klaassen R, Woodruff HC, Hatt M, Kaanders HJAM, Hamming-Vrieze O, van Laarhoven HWM, Subramiam RM, Huang SH, O'Sullivan B, Bratman SV, Dubois LJ, Miclea RL, Di Perri D, Geets X, Crispin-Ortuzar M, Apte A, Deasy JO, Oh JH, Lee NY, Humm JL, Schöder H, De Ruysscher D, Hoebers F, Lambin P. Non-invasive imaging prediction of tumor hypoxia: A novel developed and externally validated CT and FDG-PET-based radiomic signatures. Radiother Oncol. 2020 12; 153:97-105. PMID: 33137396.
    Citations: 8     Fields:    Translation:Humans
  30. Cavalieri S, De Cecco L, Brakenhoff RH, Serafini MS, Canevari S, Rossi S, Lanfranco D, Hoebers FJP, Wesseling FWR, Keek S, Scheckenbach K, Mattavelli D, Hoffmann T, López Pérez L, Fico G, Bologna M, Nauta I, Leemans CR, Trama A, Klausch T, Berkhof JH, Tountopoulos V, Shefi R, Mainardi L, Mercalli F, Poli T, Licitra L. Development of a multiomics database for personalized prognostic forecasting in head and neck cancer: The Big Data to Decide EU Project. Head Neck. 2021 02; 43(2):601-612. PMID: 33107152; PMCID: PMC7820974.
    Citations: 7     Fields:    Translation:Humans
  31. Keek S, Sanduleanu S, Wesseling F, van der Heijden M, Vens C, Giuseppina C, Licitra L, Scheckenbach K, Vergeer M, Leemans CR, Brakenhoff RH, Nauta I, Cavalieri S, Woodruff HC, Poli T, Leijenaar R, Hoebers F, Lambin P. Correction: Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy. PLoS One. 2020; 15(7):e0237048. PMID: 32722718; PMCID: PMC7386584.
    Citations: 2     Fields:    
  32. Keek S, Sanduleanu S, Wesseling F, de Roest R, van den Brekel M, van der Heijden M, Vens C, Giuseppina C, Licitra L, Scheckenbach K, Vergeer M, Leemans CR, Brakenhoff RH, Nauta I, Cavalieri S, Woodruff HC, Poli T, Leijenaar R, Hoebers F, Lambin P. Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy. PLoS One. 2020; 15(5):e0232639. PMID: 32442178; PMCID: PMC7244120.
    Citations: 14     Fields:    Translation:Humans
  33. Al-Mamgani A, Kessels R, Verhoef CG, Navran A, Hamming-Vrieze O, Kaanders JHAM, Steenbakkers RJHM, Tans L, Hoebers F, Ong F, van Werkhoven E, Langendijk JA. Randomized controlled trial to identify the optimal radiotherapy scheme for palliative treatment of incurable head and neck squamous cell carcinoma. Radiother Oncol. 2020 08; 149:181-188. PMID: 32417345.
    Citations: 3     Fields:    Translation:Humans
  34. Van den Bosch L, Schuit E, van der Laan HP, Reitsma JB, Moons KGM, Steenbakkers RJHM, Hoebers FJP, Langendijk JA, van der Schaaf A. Key challenges in normal tissue complication probability model development and validation: towards a comprehensive strategy. Radiother Oncol. 2020 07; 148:151-156. PMID: 32388149.
    Citations: 6     Fields:    Translation:Humans
  35. de Vos-Geelen J, Hoebers FJP, Geurts SME, Hoeben A, de Greef BTA, Voncken FEM, Bogers JHA, Braam PM, Muijs CKT, de Jong MA, Kasperts N, Rozema T, Jeene PM, Blom GJ, van Dieren JM, Hulshof MCCM, van Laarhoven HWM, Grabsch HI, Lemmens VEPP, Tjan-Heijnen VCG, Nieuwenhuijzen GAP. A national study to assess outcomes of definitive chemoradiation regimens in proximal esophageal cancer. Acta Oncol. 2020 Aug; 59(8):895-903. PMID: 32319845.
    Citations: 4     Fields:    Translation:Humans
  36. Sanduleanu S, Hamming-Vrieze O, Wesseling FWR, Even AJG, Hoebers FJ, Hoeben A, Vogel WV, Tesselaar MET, Parvin D, Bartelink H, Lambin P. [18F]-HX4 PET/CT hypoxia in patients with squamous cell carcinoma of the head and neck treated with chemoradiotherapy: Prognostic results from two prospective trials. Clin Transl Radiat Oncol. 2020 Jul; 23:9-15. PMID: 32368624; PMCID: PMC7184102.
    Citations: 8     
  37. Bogowicz M, Jochems A, Deist TM, Tanadini-Lang S, Huang SH, Chan B, Waldron JN, Bratman S, O'Sullivan B, Riesterer O, Studer G, Unkelbach J, Barakat S, Brakenhoff RH, Nauta I, Gazzani SE, Calareso G, Scheckenbach K, Hoebers F, Wesseling FWR, Keek S, Sanduleanu S, Leijenaar RTH, Vergeer MR, Leemans CR, Terhaard CHJ, van den Brekel MWM, Hamming-Vrieze O, van der Heijden MA, Elhalawani HM, Fuller CD, Guckenberger M, Lambin P. Privacy-preserving distributed learning of radiomics to predict overall survival and HPV status in head and neck cancer. Sci Rep. 2020 03 11; 10(1):4542. PMID: 32161279.
    Citations: 11     Fields:    Translation:HumansCells
  38. Straetmans JMJAA, Stuut M, Wagemakers S, Hoebers F, Kaanders JHAM, Speel EJM, Melchers WJG, Slootweg P, Kremer B, Lacko M, Takes RP. Tumor control of cervical lymph node metastases of unknown primary origin: the impact of the radiotherapy target volume. Eur Arch Otorhinolaryngol. 2020 Jun; 277(6):1753-1761. PMID: 32100130.
    Citations: 2     Fields:    Translation:Humans
  39. Welch ML, McIntosh C, McNiven A, Huang SH, Zhang BB, Wee L, Traverso A, O'Sullivan B, Hoebers F, Dekker A, Jaffray DA. User-controlled pipelines for feature integration and head and neck radiation therapy outcome predictions. Phys Med. 2020 Feb; 70:145-152. PMID: 32023504.
    Citations: 6     Fields:    Translation:Humans
  40. van der Heijden M, Essers PBM, de Jong MC, de Roest RH, Sanduleanu S, Verhagen CVM, Hamming-Vrieze O, Hoebers F, Lambin P, Bartelink H, Leemans CR, Verheij M, Brakenhoff RH, van den Brekel MWM, Vens C. Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation. Front Oncol. 2019; 9:1470. PMID: 31998639; PMCID: PMC6966332.
    Citations: 11     
  41. de Vos-Geelen J, Geurts SM, van Putten M, Valkenburg-van Iersel LB, Grabsch HI, Haj Mohammad N, Hoebers FJ, Hoge CV, Jeene PM, de Jong EJ, van Laarhoven HW, Rozema T, Slingerland M, Tjan-Heijnen VC, Nieuwenhuijzen GA, Lemmens VE. Trends in treatment and overall survival among patients with proximal esophageal cancer. World J Gastroenterol. 2019 Dec 21; 25(47):6835-6846. PMID: 31885424; PMCID: PMC6931002.
    Citations: 5     Fields:    Translation:Humans
  42. Willemsen ACH, Kok A, van Kuijk SMJ, Baijens LWJ, de Bree R, Devriese LA, Hoebers FJP, Lalisang RI, Schols AMWJ, Terhaard CHJ, Hoeben A. Prediction model for tube feeding dependency during chemoradiotherapy for at least four weeks in head and neck cancer patients: A tool for prophylactic gastrostomy decision making. Clin Nutr. 2020 08; 39(8):2600-2608. PMID: 31839429.
    Citations: 4     Fields:    Translation:Humans
  43. Willemsen ACH, Hoeben A, Lalisang RI, Van Helvoort A, Wesseling FWR, Hoebers F, Baijens LWJ, Schols AMWJ. Disease-induced and treatment-induced alterations in body composition in locally advanced head and neck squamous cell carcinoma. J Cachexia Sarcopenia Muscle. 2020 02; 11(1):145-159. PMID: 31536685; PMCID: PMC7015232.
    Citations: 17     Fields:    Translation:Humans
  44. van der Heijden M, de Jong MC, Verhagen CVM, de Roest RH, Sanduleanu S, Hoebers F, Leemans CR, Brakenhoff RH, Vens C, Verheij M, van den Brekel MWM. Acute Hypoxia Profile is a Stronger Prognostic Factor than Chronic Hypoxia in Advanced Stage Head and Neck Cancer Patients. Cancers (Basel). 2019 Apr 25; 11(4). PMID: 31027242; PMCID: PMC6520712.
    Citations: 7     
  45. Petersen JF, Berlanga A, Stuiver MM, Hamming-Vrieze O, Hoebers F, Lambin P, van den Brekel MWM. Improving decision making in larynx cancer by developing a decision aid: A mixed methods approach. Laryngoscope. 2019 12; 129(12):2733-2739. PMID: 30663068; PMCID: PMC6899876.
    Citations: 3     Fields:    Translation:Humans
  46. Deist TM, Dankers FJWM, Valdes G, Wijsman R, Hsu IC, Oberije C, Lustberg T, van Soest J, Hoebers F, Jochems A, El Naqa I, Wee L, Morin O, Raleigh DR, Bots W, Kaanders JH, Belderbos J, Kwint M, Solberg T, Monshouwer R, Bussink J, Dekker A, Lambin P. Erratum: "Machine learning algorithms for outcome prediction in (chemo)radiotherapy: An empirical comparison of classifiers" [Med. Phys. 45 (7), 3449-3459 (2018)]. Med Phys. 2019 Feb; 46(2):1080-1087. PMID: 30730570.
    Citations: 4     Fields:    
  47. van Overveld LFJ, Takes RP, Braspenning JCC, Baatenburg de Jong RJ, de Boer JP, Brouns JJA, Bun RJ, Dik EA, van Dijk BAC, van Es RJJ, Hoebers FJP, Kolenaar B, Kropveld A, Langeveld TPM, Verschuur HP, de Visscher JGAM, van Weert S, Witjes MJH, Smeele LE, Merkx MAW, Hermens RPMG. Variation in Integrated Head and Neck Cancer Care: Impact of Patient and Hospital Characteristics. J Natl Compr Canc Netw. 2018 12; 16(12):1491-1498. PMID: 30545996.
    Citations: 8     Fields:    Translation:Humans
  48. van den Bosch S, Dijkema T, Philippens MEP, Terhaard CHJ, Hoebers FJP, Kaanders JHAM, Oyen WJG. Tumor to cervical spinal cord standardized uptake ratio (SUR) improves the reproducibility of 18F-FDG-PET based tumor segmentation in head and neck squamous cell carcinoma in a multicenter setting. Radiother Oncol. 2019 01; 130:39-45. PMID: 30005954.
    Citations: 2     Fields:    Translation:Humans
  49. Deist TM, Dankers FJWM, Valdes G, Wijsman R, Hsu IC, Oberije C, Lustberg T, van Soest J, Hoebers F, Jochems A, El Naqa I, Wee L, Morin O, Raleigh DR, Bots W, Kaanders JH, Belderbos J, Kwint M, Solberg T, Monshouwer R, Bussink J, Dekker A, Lambin P. Machine learning algorithms for outcome prediction in (chemo)radiotherapy: An empirical comparison of classifiers. Med Phys. 2018 Jul; 45(7):3449-3459. PMID: 29763967; PMCID: PMC6095141.
    Citations: 89     Fields:    Translation:Humans
  50. Leijenaar RT, Bogowicz M, Jochems A, Hoebers FJ, Wesseling FW, Huang SH, Chan B, Waldron JN, O'Sullivan B, Rietveld D, Leemans CR, Brakenhoff RH, Riesterer O, Tanadini-Lang S, Guckenberger M, Ikenberg K, Lambin P. Development and validation of a radiomic signature to predict HPV (p16) status from standard CT imaging: a multicenter study. Br J Radiol. 2018 Jun; 91(1086):20170498. PMID: 29451412; PMCID: PMC6223271.
    Citations: 47     Fields:    Translation:HumansCells
  51. Haumann J, van Kuijk SMJ, Geurts JW, Hoebers FJP, Kremer B, Joosten EA, van den Beuken-van Everdingen MHJ. Methadone versus Fentanyl in Patients with Radiation-Induced Nociceptive Pain with Head and Neck Cancer: A Randomized Controlled Noninferiority Trial. Pain Pract. 2018 03; 18(3):331-340. PMID: 28691202.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  52. Velazquez ER, Hoebers F, Aerts HJWL, Rietbergen MM, Brakenhoff RH, Leemans RC, Speel EJ, Straetmans J, Kremer B, Lambin P. Corrigendum to "Externally validated HPV-based prognostic nomogram for oropharyngeal carcinoma patients yields more accurate predictions than TNM staging" [Radiother Oncol 113 (2014) 324-30]. Radiother Oncol. 2017 08; 124(2):337-338. PMID: 28709696.
    Citations: 1     Fields:    
  53. Poort LJ, Stadler AAR, Ludlage JHB, Hoebers FJP, Kessler PAWH, Postma AA. Detection of Bone Marrow Edema Pattern With Dual-Energy Computed Tomography of the Pig Mandible Treated With Radiotherapy and Surgery Compared With Magnetic Resonance Imaging. J Comput Assist Tomogr. 2017 Jul/Aug; 41(4):553-558. PMID: 28722700.
    Citations: 5     Fields:    Translation:Animals
  54. van Overveld LFJ, Takes RP, Vijn TW, Braspenning JCC, de Boer JP, Brouns JJA, Bun RJ, van Dijk BAC, Dortmans JAWF, Dronkers EAC, van Es RJJ, Hoebers FJP, Kropveld A, Langendijk JA, Langeveld TPM, Oosting SF, Verschuur HP, de Visscher JGAM, van Weert S, Merkx MAW, Smeele LE, Hermens RPMG. Feedback preferences of patients, professionals and health insurers in integrated head and neck cancer care. Health Expect. 2017 12; 20(6):1275-1288. PMID: 28618147; PMCID: PMC5689243.
    Citations: 3     Fields:    Translation:Humans
  55. van den Bosch S, Dijkema T, Kunze-Busch MC, Terhaard CH, Raaijmakers CP, Doornaert PA, Hoebers FJ, Vergeer MR, Kreike B, Wijers OB, Oyen WJ, Kaanders JH. Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma. BMC Cancer. 2017 03 21; 17(1):208. PMID: 28327089; PMCID: PMC5361684.
    Citations: 7     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  56. Poort LJ, Ludlage JHB, Lie N, Böckmann RA, Odekerken JCE, Hoebers FJ, Kessler PAWH. The histological and histomorphometric changes in the mandible after radiotherapy: An animal model. J Craniomaxillofac Surg. 2017 May; 45(5):716-721. PMID: 28336321.
    Citations: 6     Fields:    Translation:Animals
  57. Poort LJ, Postma AA, Stadler AAR, Böckmann RA, Hoebers FJ, Kessler PAWH. Radiological changes with magnetic resonance imaging and computed tomography after irradiating minipig mandibles: The role of T2-SPIR mixed signal intensities in the detection of osteoradionecrosis. J Craniomaxillofac Surg. 2017 May; 45(5):607-613. PMID: 28318917.
    Citations: 1     Fields:    Translation:Animals
  58. Even AJ, Hamming-Vrieze O, van Elmpt W, Winnepenninckx VJ, Heukelom J, Tesselaar ME, Vogel WV, Hoeben A, Zegers CM, Vugts DJ, van Dongen GA, Bartelink H, Mottaghy FM, Hoebers F, Lambin P. Quantitative assessment of Zirconium-89 labeled cetuximab using PET/CT imaging in patients with advanced head and neck cancer: a theragnostic approach. Oncotarget. 2017 Jan 17; 8(3):3870-3880. PMID: 27965472; PMCID: PMC5354801.
    Citations: 24     Fields:    Translation:Humans
  59. van Loon J, Even AJG, Aerts HJWL, Öllers M, Hoebers F, van Elmpt W, Dubois L, Dingemans AC, Lalisang RI, Kempers P, Brans B, Winnepenninckx V, Speel EJ, Thunnissen E, Smits KM, Boellaard R, Vugts DJ, De Ruysscher D, Lambin P. PET imaging of zirconium-89 labelled cetuximab: A phase I trial in patients with head and neck and lung cancer. Radiother Oncol. 2017 02; 122(2):267-273. PMID: 28012793.
    Citations: 25     Fields:    Translation:HumansCTClinical Trials
  60. Eekers DBP, Roelofs E, Jelen U, Kirk M, Granzier M, Ammazzalorso F, Ahn PH, Janssens GORJ, Hoebers FJP, Friedmann T, Solberg T, Walsh S, Troost EGC, Kaanders JHAM, Lambin P. Benefit of particle therapy in re-irradiation of head and neck patients. Results of a multicentric in silico ROCOCO trial. Radiother Oncol. 2016 12; 121(3):387-394. PMID: 27639891.
    Citations: 21     Fields:    Translation:HumansCTClinical Trials
  61. Poort LJ, Kiewiet CC, Cleutjens JP, Houben R, Hoebers FJ, Kessler PA. Osseointegration and implant stability of extraoral implants in Göttingen minipigs after irradiation. J Craniomaxillofac Surg. 2016 Nov; 44(11):1842-1848. PMID: 27697399.
    Citations:    Fields:    Translation:Animals
  62. Lustberg T, Bailey M, Thwaites DI, Miller A, Carolan M, Holloway L, Rios Velazquez E, Hoebers F, Dekker A. Implementation of a rapid learning platform: Predicting 2-year survival in laryngeal carcinoma patients in a clinical setting. Oncotarget. 2016 Jun 14; 7(24):37288-37296. PMID: 27095578.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  63. Zegers CM, Hoebers FJ, van Elmpt W, Bons JA, Öllers MC, Troost EG, Eekers D, Balmaekers L, Arts-Pechtold M, Mottaghy FM, Lambin P. Evaluation of tumour hypoxia during radiotherapy using [18F]HX4 PET imaging and blood biomarkers in patients with head and neck cancer. Eur J Nucl Med Mol Imaging. 2016 Nov; 43(12):2139-2146. PMID: 27251643; PMCID: PMC5047929.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  64. Hoeben A, van de Winkel L, Hoebers F, Kross K, Driessen C, Slootweg P, Tjan-Heijnen VC, van Herpen C. Intestinal-type sinonasal adenocarcinomas: The road to molecular diagnosis and personalized treatment. Head Neck. 2016 10; 38(10):1564-70. PMID: 27224655.
    Citations: 11     Fields:    Translation:Humans
  65. Hoeben A, Polak J, Van De Voorde L, Hoebers F, Grabsch HI, de Vos-Geelen J. Cervical esophageal cancer: a gap in cancer knowledge. Ann Oncol. 2016 09; 27(9):1664-74. PMID: 27117535.
    Citations: 37     Fields:    Translation:Humans
  66. O'Sullivan B, Huang SH, Su J, Garden AS, Sturgis EM, Dahlstrom K, Lee N, Riaz N, Pei X, Koyfman SA, Adelstein D, Burkey BB, Friborg J, Kristensen CA, Gothelf AB, Hoebers F, Kremer B, Speel EJ, Bowles DW, Raben D, Karam SD, Yu E, Xu W. Development and validation of a staging system for HPV-related oropharyngeal cancer by the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S): a multicentre cohort study. Lancet Oncol. 2016 04; 17(4):440-451. PMID: 26936027.
    Citations: 211     Fields:    Translation:HumansCells
  67. Cheng Q, Roelofs E, Ramaekers BL, Eekers D, van Soest J, Lustberg T, Hendriks T, Hoebers F, van der Laan HP, Korevaar EW, Dekker A, Langendijk JA, Lambin P. Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness. Radiother Oncol. 2016 Feb; 118(2):281-5. PMID: 26924342.
    Citations: 25     Fields:    Translation:Humans
  68. Brinkhuizen T, van Geel M, Denil SL, De Meyer T, Kelleners-Smeets NW, Lohuis PJ, Hoebers FJ, Winnepenninckx VJ, van Steensel MA, Mosterd K. Locally advanced basal cell carcinoma has a distinct methylation and transcriptomic profile. Exp Dermatol. 2016 Apr; 25(4):316-8. PMID: 26662714.
    Citations:    Fields:    Translation:HumansCells
  69. Lambin P, Zindler J, Vanneste BG, De Voorde LV, Eekers D, Compter I, Panth KM, Peerlings J, Larue RT, Deist TM, Jochems A, Lustberg T, van Soest J, de Jong EE, Even AJ, Reymen B, Rekers N, van Gisbergen M, Roelofs E, Carvalho S, Leijenaar RT, Zegers CM, Jacobs M, van Timmeren J, Brouwers P, Lal JA, Dubois L, Yaromina A, Van Limbergen EJ, Berbee M, van Elmpt W, Oberije C, Ramaekers B, Dekker A, Boersma LJ, Hoebers F, Smits KM, Berlanga AJ, Walsh S. Decision support systems for personalized and participative radiation oncology. Adv Drug Deliv Rev. 2017 01 15; 109:131-153. PMID: 26774327.
    Citations: 42     Fields:    Translation:Humans
  70. Poort LJ, Bloebaum MM, Böckmann RA, Houben R, Granzier ME, Hoebers FJ, Kessler PA. Assessment of local blood flow with laser Doppler flowmetry in irradiated mandibular and frontal bone, an experiment in Göttingen minipigs. J Craniomaxillofac Surg. 2015 Dec; 43(10):2071-7. PMID: 26776291.
    Citations:    Fields:    Translation:Animals
  71. Lambin P, Zindler J, Vanneste B, van de Voorde L, Jacobs M, Eekers D, Peerlings J, Reymen B, Larue RT, Deist TM, de Jong EE, Even AJ, Berlanga AJ, Roelofs E, Cheng Q, Carvalho S, Leijenaar RT, Zegers CM, van Limbergen E, Berbee M, van Elmpt W, Oberije C, Houben R, Dekker A, Boersma L, Verhaegen F, Bosmans G, Hoebers F, Smits K, Walsh S. Modern clinical research: How rapid learning health care and cohort multiple randomised clinical trials complement traditional evidence based medicine. Acta Oncol. 2015; 54(9):1289-300. PMID: 26395528.
    Citations: 26     Fields:    Translation:Humans
  72. Belhocine TZ, Blankenberg FG, Kartachova MS, Stitt LW, Vanderheyden JL, Hoebers FJ, Van de Wiele C. (99m)Tc-Annexin A5 quantification of apoptotic tumor response: a systematic review and meta-analysis of clinical imaging trials. Eur J Nucl Med Mol Imaging. 2015 Dec; 42(13):2083-97. PMID: 26275392.
    Citations: 15     Fields:    Translation:Humans
  73. Leijenaar RT, Carvalho S, Hoebers FJ, Aerts HJ, van Elmpt WJ, Huang SH, Chan B, Waldron JN, O'sullivan B, Lambin P. External validation of a prognostic CT-based radiomic signature in oropharyngeal squamous cell carcinoma. Acta Oncol. 2015; 54(9):1423-9. PMID: 26264429.
    Citations: 90     Fields:    Translation:Humans
  74. Zerp SF, Stoter TR, Hoebers FJ, van den Brekel MW, Dubbelman R, Kuipers GK, Lafleur MV, Slotman BJ, Verheij M. Targeting anti-apoptotic Bcl-2 by AT-101 to increase radiation efficacy: data from in vitro and clinical pharmacokinetic studies in head and neck cancer. Radiat Oncol. 2015 Jul 30; 10:158. PMID: 26223311; PMCID: PMC4520130.
    Citations: 16     Fields:    Translation:HumansCellsCTClinical Trials
  75. Hermans BC, Persoon LC, Podesta M, Hoebers FJ, Verhaegen F, Troost EG. Weekly kilovoltage cone-beam computed tomography for detection of dose discrepancies during (chemo)radiotherapy for head and neck cancer. Acta Oncol. 2015; 54(9):1483-9. PMID: 26219958.
    Citations: 6     Fields:    Translation:Humans
  76. Zegers CM, van Elmpt W, Hoebers FJ, Troost EG, Öllers MC, Mottaghy FM, Lambin P. Imaging of tumour hypoxia and metabolism in patients with head and neck squamous cell carcinoma. Acta Oncol. 2015; 54(9):1378-84. PMID: 26213313.
    Citations: 2     Fields:    Translation:Humans
  77. Simons PA, Ramaekers B, Hoebers F, Kross KW, Marneffe W, Pijls-Johannesma M, Vandijck D. Cost-Effectiveness of Reduced Waiting Time for Head and Neck Cancer Patients due to a Lean Process Redesign. Value Health. 2015 Jul; 18(5):587-96. PMID: 26297086.
    Citations: 3     Fields:    Translation:Humans
  78. van Harten MC, Hoebers FJ, Kross KW, van Werkhoven ED, van den Brekel MW, van Dijk BA. Determinants of treatment waiting times for head and neck cancer in the Netherlands and their relation to survival. Oral Oncol. 2015 Mar; 51(3):272-8. PMID: 25541458.
    Citations: 55     Fields:    Translation:Humans
  79. Wilbers J, Dorresteijn LD, Haast R, Hoebers FJ, Kaanders JH, Boogerd W, van Werkhoven ED, Nowee ME, Hansen HH, de Korte CL, Kappelle AC, van Dijk EJ. Progression of carotid intima media thickness after radiotherapy: a long-term prospective cohort study. Radiother Oncol. 2014 Dec; 113(3):359-63. PMID: 25466374.
    Citations: 16     Fields:    Translation:Humans
  80. Rios Velazquez E, Hoebers F, Aerts HJ, Rietbergen MM, Brakenhoff RH, Leemans RC, Speel EJ, Straetmans J, Kremer B, Lambin P. Externally validated HPV-based prognostic nomogram for oropharyngeal carcinoma patients yields more accurate predictions than TNM staging. Radiother Oncol. 2014 Dec; 113(3):324-30. PMID: 25443497.
    Citations: 26     Fields:    Translation:HumansCells
  81. Zegers CM, van Elmpt W, Reymen B, Even AJ, Troost EG, Ollers MC, Hoebers FJ, Houben RM, Eriksson J, Windhorst AD, Mottaghy FM, De Ruysscher D, Lambin P. In vivo quantification of hypoxic and metabolic status of NSCLC tumors using [18F]HX4 and [18F]FDG-PET/CT imaging. Clin Cancer Res. 2014 Dec 15; 20(24):6389-97. PMID: 25316821; PMCID: PMC5228298.
    Citations: 31     Fields:    Translation:Humans
  82. Wilbers J, Hoebers FJ, Boogerd W, van Werkhoven ED, Nowee ME, Hart G, Bartelink H, van Dijk EJ, Kappelle AC, Dorresteijn LD. Prospective cohort study of carotid intima-media thickness after irradiation. J Stroke Cerebrovasc Dis. 2014 Nov-Dec; 23(10):2701-2707. PMID: 25304721.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  83. De Ruyck K, Duprez F, Ferdinande L, Mbah C, Rios-Velazquez E, Hoebers F, Praet M, Deron P, Bonte K, Speel EJ, Libbrecht L, De Neve W, Lambin P, Thierens H. A let-7 microRNA polymorphism in the KRAS 3'-UTR is prognostic in oropharyngeal cancer. Cancer Epidemiol. 2014 Oct; 38(5):591-8. PMID: 25127693.
    Citations: 12     Fields:    Translation:Humans
  84. Wilbers J, Kappelle AC, Kessels RP, Steens SC, Meijer FJ, Kaanders JH, Haast RA, Versteeg LE, Tuladhar AM, de Korte CL, Hansen HH, Hoebers FJ, Boogerd W, van Werkhoven ED, Nowee ME, Hart G, Bartelink H, Dorresteijn LD, van Dijk EJ. Long term cerebral and vascular complications after irradiation of the neck in head and neck cancer patients: a prospective cohort study: study rationale and protocol. BMC Neurol. 2014 Jun 19; 14:132. PMID: 24942263; PMCID: PMC4077148.
    Citations: 6     Fields:    Translation:Humans
  85. Aerts HJ, Velazquez ER, Leijenaar RT, Parmar C, Grossmann P, Carvalho S, Cavalho S, Bussink J, Monshouwer R, Haibe-Kains B, Rietveld D, Hoebers F, Rietbergen MM, Leemans CR, Dekker A, Quackenbush J, Gillies RJ, Lambin P. Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach. Nat Commun. 2014 Jun 03; 5:4006. PMID: 24892406.
    Citations: 1692     Fields:    Translation:Humans
  86. Poort LJ, Bittermann GK, Böckmann RA, Hoebers FJ, Houben R, Postma AA, Kessler PA. Does a change in bone mineral density occur in the mandible of Göttingen minipigs after irradiation in correlation with radiation dose and implant surgery? J Oral Maxillofac Surg. 2014 Nov; 72(11):2149-56. PMID: 25438274.
    Citations:    Fields:    Translation:Animals
  87. Straetmans J, Vent J, Lacko M, Speel EJ, Huebbers C, Semrau R, Hoebers F, Mujagic Z, Klussmann JP, Preuss SF, Kremer B. Management of neck metastases of unknown primary origin united in two European centers. Eur Arch Otorhinolaryngol. 2015 Jan; 272(1):195-205. PMID: 24615648.
    Citations: 7     Fields:    Translation:Humans
  88. Zegers CM, van Elmpt W, Wierts R, Reymen B, Sharifi H, Öllers MC, Hoebers F, Troost EG, Wanders R, van Baardwijk A, Brans B, Eriksson J, Windhorst B, Mottaghy FM, De Ruysscher D, Lambin P. Hypoxia imaging with [¹8F]HX4 PET in NSCLC patients: defining optimal imaging parameters. Radiother Oncol. 2013 Oct; 109(1):58-64. PMID: 24044790.
    Citations: 32     Fields:    Translation:Humans
  89. Lambin P, Roelofs E, Reymen B, Velazquez ER, Buijsen J, Zegers CM, Carvalho S, Leijenaar RT, Nalbantov G, Oberije C, Scott Marshall M, Hoebers F, Troost EG, van Stiphout RG, van Elmpt W, van der Weijden T, Boersma L, Valentini V, Dekker A. 'Rapid Learning health care in oncology' - an approach towards decision support systems enabling customised radiotherapy'. Radiother Oncol. 2013 Oct; 109(1):159-64. PMID: 23993399.
    Citations: 62     Fields:    Translation:Humans
  90. Hoebers F, Rios E, Troost E, van den Ende P, Kross K, Lacko M, Lalisang R, Kremer B, de Jong J. Definitive radiation therapy for treatment of laryngeal carcinoma: impact of local relapse on outcome and implications for treatment strategies. Strahlenther Onkol. 2013 Oct; 189(10):834-41. PMID: 23974824.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  91. Remmelts AJ, Hoebers FJ, Klop WM, Balm AJ, Hamming-Vrieze O, van den Brekel MW. Evaluation of lasersurgery and radiotherapy as treatment modalities in early stage laryngeal carcinoma: tumour outcome and quality of voice. Eur Arch Otorhinolaryngol. 2013 Jul; 270(7):2079-87. PMID: 23568036.
    Citations: 29     Fields:    Translation:Humans
  92. Heukelom J, Hamming O, Bartelink H, Hoebers F, Giralt J, Herlestam T, Verheij M, van den Brekel M, Vogel W, Slevin N, Deutsch E, Sonke JJ, Lambin P, Rasch C. Adaptive and innovative Radiation Treatment FOR improving Cancer treatment outcomE (ARTFORCE); a randomized controlled phase II trial for individualized treatment of head and neck cancer. BMC Cancer. 2013 Feb 22; 13:84. PMID: 23433435; PMCID: PMC3599345.
    Citations: 34     Fields:    Translation:HumansCTClinical Trials
  93. Hoebers F, Yu E, Eisbruch A, Thorstad W, O'Sullivan B, Dawson LA, Hope A. A pragmatic contouring guideline for salivary gland structures in head and neck radiation oncology: the MOIST target. Am J Clin Oncol. 2013 Feb; 36(1):70-6. PMID: 22237147.
    Citations: 8     Fields:    Translation:Humans
  94. De Ruysscher D, Belderbos J, Reymen B, van Elmpt W, van Baardwijk A, Wanders R, Hoebers F, Vooijs M, Ollers M, Lambin P. State of the art radiation therapy for lung cancer 2012: a glimpse of the future. Clin Lung Cancer. 2013 Mar; 14(2):89-95. PMID: 22853981.
    Citations: 14     Fields:    Translation:Humans
  95. Karakullukçu B, van der Vlies D, Hoebers FJ. A rare late complication after concomitant chemoradiation of an oropharyngeal tumor: cervical necrotizing fasciitis. Kulak Burun Bogaz Ihtis Derg. 2012 Mar-Apr; 22(2):105-8. PMID: 22548268.
    Citations:    Fields:    Translation:Humans
  96. Karakullukcu B, Nyst HJ, van Veen RL, Hoebers FJ, Hamming-Vrieze O, Witjes MJ, de Visscher SA, Burlage FR, Levendag PC, Sterenborg HJ, Tan IB. mTHPC mediated interstitial photodynamic therapy of recurrent nonmetastatic base of tongue cancers: Development of a new method. Head Neck. 2012 Nov; 34(11):1597-606. PMID: 22290724.
    Citations: 17     Fields:    Translation:HumansCTClinical Trials
  97. Hoebers FJ, Ordonez BP, Irish J, Simpson RE, Yu E, O'Sullivan B. Progressive tumefactive fibroinflammatory lesion of the infratemporal fossa treated by radiation therapy. Rare Tumors. 2012 Jan 02; 4(1):e12. PMID: 22532910; PMCID: PMC3325739.
    Citations: 4     
  98. Fitton I, Cornelissen SA, Duppen JC, Steenbakkers RJ, Peeters ST, Hoebers FJ, Kaanders JH, Nowak PJ, Rasch CR, van Herk M. Semi-automatic delineation using weighted CT-MRI registered images for radiotherapy of nasopharyngeal cancer. Med Phys. 2011 Aug; 38(8):4662-6. PMID: 21928639.
    Citations: 4     Fields:    Translation:Humans
  99. Egelmeer AG, Velazquez ER, de Jong JM, Oberije C, Geussens Y, Nuyts S, Kremer B, Rietveld D, Leemans CR, de Jong MC, Rasch C, Hoebers F, Homer J, Slevin N, West C, Lambin P. Development and validation of a nomogram for prediction of survival and local control in laryngeal carcinoma patients treated with radiotherapy alone: a cohort study based on 994 patients. Radiother Oncol. 2011 Jul; 100(1):108-15. PMID: 21784544.
    Citations: 20     Fields:    Translation:Humans
  100. Knegjens JL, Hauptmann M, Pameijer FA, Balm AJ, Hoebers FJ, de Bois JA, Kaanders JH, van Herpen CM, Verhoef CG, Wijers OB, Wiggenraad RG, Buter J, Rasch CR. Tumor volume as prognostic factor in chemoradiation for advanced head and neck cancer. Head Neck. 2011 Mar; 33(3):375-82. PMID: 20629076.
    Citations: 34     Fields:    Translation:Humans
  101. Hoebers F, Heemsbergen W, Moor S, Lopez M, Klop M, Tesselaar M, Rasch C. Reirradiation for head-and-neck cancer: delicate balance between effectiveness and toxicity. Int J Radiat Oncol Biol Phys. 2011 Nov 01; 81(3):e111-8. PMID: 21362581.
    Citations: 27     Fields:    Translation:Humans
  102. de Jong MC, Pramana J, van der Wal JE, Lacko M, Peutz-Kootstra CJ, de Jong JM, Takes RP, Kaanders JH, van der Laan BF, Wachters J, Jansen JC, Rasch CR, van Velthuysen ML, Grénman R, Hoebers FJ, Schuuring E, van den Brekel MW, Begg AC. CD44 expression predicts local recurrence after radiotherapy in larynx cancer. Clin Cancer Res. 2010 Nov 01; 16(21):5329-38. PMID: 20837694.
    Citations: 65     Fields:    Translation:HumansCells
  103. Balm AJ, van Velthuysen ML, Hoebers FJ, Vogel WV, van den Brekel MW. Diagnosis and treatment of a neck node swelling suspicious for a malignancy: an algorithmic approach. Int J Surg Oncol. 2010; 2010:581540. PMID: 22312490; PMCID: PMC3265261.
    Citations: 4     Fields:    
  104. Rasch CR, Hauptmann M, Schornagel J, Wijers O, Buter J, Gregor T, Wiggenraad R, de Boer JP, Ackerstaff AH, Kroger R, Hoebers FJ, Balm AJ, Hilgers FJ. Intra-arterial versus intravenous chemoradiation for advanced head and neck cancer: Results of a randomized phase 3 trial. Cancer. 2010 May 01; 116(9):2159-65. PMID: 20187094.
    Citations: 33     Fields:    Translation:HumansCTClinical Trials
  105. van der Putten L, van den Broek GB, de Bree R, van den Brekel MW, Balm AJ, Hoebers FJ, Doornaert P, Leemans CR, Rasch CR. Effectiveness of salvage selective and modified radical neck dissection for regional pathologic lymphadenopathy after chemoradiation. Head Neck. 2009 May; 31(5):593-603. PMID: 19132716.
    Citations: 17     Fields:    Translation:Humans
  106. Wildeman MA, Gibcus JH, Hauptmann M, Begg AC, van Velthuysen ML, Hoebers FJ, Mastik MF, Schuuring E, van der Wal JE, van den Brekel MW. Radiotherapy in laryngeal carcinoma: can a panel of 13 markers predict response? Laryngoscope. 2009 Feb; 119(2):316-22. PMID: 19160427.
    Citations: 13     Fields:    Translation:Humans
  107. Hoebers FJ, Pameijer FA, de Bois J, Heemsbergen W, Balm AJ, Schornagel JH, Rasch CR. Prognostic value of primary tumor volume after concurrent chemoradiation with daily low-dose cisplatin for advanced-stage head and neck carcinoma. Head Neck. 2008 Sep; 30(9):1216-23. PMID: 18642295.
    Citations: 14     Fields:    Translation:Humans
  108. Kartachova MS, Valdés Olmos RA, Haas RL, Hoebers FJ, van Herk M, Verheij M. 99mTc-HYNIC-rh-annexin-V scintigraphy: visual and quantitative evaluation of early treatment-induced apoptosis to predict treatment outcome. Nucl Med Commun. 2008 Jan; 29(1):39-44. PMID: 18049096.
    Citations: 21     Fields:    Translation:HumansCTClinical Trials
  109. Thomas G, Ali S, Hoebers FJ, Darcy KM, Rodgers WH, Patel M, Abulafia O, Lucci JA, Begg AC. Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dL with erythropoietin vs above 10.0 g/dL without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer. Gynecol Oncol. 2008 Feb; 108(2):317-25. PMID: 18037478; PMCID: PMC2350198.
    Citations: 50     Fields:    Translation:HumansCTClinical Trials
  110. Hoebers FJ, Kartachova M, de Bois J, van den Brekel MW, van Tinteren H, van Herk M, Rasch CR, Valdés Olmos RA, Verheij M. 99mTc Hynic-rh-Annexin V scintigraphy for in vivo imaging of apoptosis in patients with head and neck cancer treated with chemoradiotherapy. Eur J Nucl Med Mol Imaging. 2008 Mar; 35(3):509-18. PMID: 17994297; PMCID: PMC2275773.
    Citations: 29     Fields:    Translation:Humans
  111. Pramana J, Van den Brekel MW, van Velthuysen ML, Wessels LF, Nuyten DS, Hofland I, Atsma D, Pimentel N, Hoebers FJ, Rasch CR, Begg AC. Gene expression profiling to predict outcome after chemoradiation in head and neck cancer. Int J Radiat Oncol Biol Phys. 2007 Dec 01; 69(5):1544-52. PMID: 17931799.
    Citations: 19     Fields:    Translation:HumansCTClinical Trials
  112. Hoebers FJ, Pluim D, Hart AA, Verheij M, Balm AJ, Fons G, Rasch CR, Schellens JH, Stalpers LJ, Bartelink H, Begg AC. Cisplatin-DNA adduct formation in patients treated with cisplatin-based chemoradiation: lack of correlation between normal tissues and primary tumor. Cancer Chemother Pharmacol. 2008 May; 61(6):1075-81. PMID: 17639394; PMCID: PMC2270367.
    Citations: 7     Fields:    Translation:Humans
  113. Oskam IM, Hoebers F, Balm AJ, van Coevorden F, Bais EM, Hart AM, van den Brekel MW. Neck management in medullary thyroid carcinoma. Eur J Surg Oncol. 2008 Jan; 34(1):71-6. PMID: 17555910.
    Citations: 6     Fields:    Translation:Humans
  114. Jonkman A, Kaanders JH, Terhaard CH, Hoebers FJ, van den Ende PL, Wijers OB, Verhoef LC, de Jong MA, Leemans CR, Langendijk JA. Multicenter validation of recursive partitioning analysis classification for patients with squamous cell head and neck carcinoma treated with surgery and postoperative radiotherapy. Int J Radiat Oncol Biol Phys. 2007 May 01; 68(1):119-25. PMID: 17448870.
    Citations: 2     Fields:    Translation:Humans
  115. Hoebers FJ, Heemsbergen W, Balm AJ, van Zanten M, Schornagel JH, Rasch CR. Concurrent chemoradiation with daily low dose cisplatin for advanced stage head and neck carcinoma. Radiother Oncol. 2007 Oct; 85(1):42-7. PMID: 17445927.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  116. Hoebers FJ, Pluim D, Verheij M, Balm AJ, Bartelink H, Schellens JH, Begg AC. Prediction of treatment outcome by cisplatin-DNA adduct formation in patients with stage III/IV head and neck squamous cell carcinoma, treated by concurrent cisplatin-radiation (RADPLAT). Int J Cancer. 2006 Aug 15; 119(4):750-6. PMID: 16550603.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  117. Kartachova MS, Valdés Olmos RA, Haas RL, Hoebers FJ, van den Brekel MW, van Zandwijk N, Herk Mv, Verheij M. Mapping of treatment-induced apoptosis in normal structures: 99mTc-Hynic-rh-annexin V SPECT and CT image fusion. Eur J Nucl Med Mol Imaging. 2006 Aug; 33(8):893-9. PMID: 16586080.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  118. Kartachova M, Haas RL, Olmos RA, Hoebers FJ, van Zandwijk N, Verheij M. In vivo imaging of apoptosis by 99mTc-Annexin V scintigraphy: visual analysis in relation to treatment response. Radiother Oncol. 2004 Sep; 72(3):333-9. PMID: 15450733.
    Citations: 35     Fields:    Translation:Humans
  119. Janssen HL, Hoebers FJ, Sprong D, Goethals L, Williams KJ, Stratford IJ, Haustermans KM, Balm AJ, Begg AC. Differentiation-associated staining with anti-pimonidazole antibodies in head and neck tumors. Radiother Oncol. 2004 Jan; 70(1):91-7. PMID: 15036858.
    Citations: 6     Fields:    Translation:Humans
  120. Janssen HL, Haustermans KM, Sprong D, Blommestijn G, Hofland I, Hoebers FJ, Blijweert E, Raleigh JA, Semenza GL, Varia MA, Balm AJ, van Velthuysen ML, Delaere P, Sciot R, Begg AC. HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors. Int J Radiat Oncol Biol Phys. 2002 Dec 01; 54(5):1537-49. PMID: 12459383.
    Citations: 34     Fields:    Translation:HumansCells
  121. Hoebers FJ, Janssen HL, Olmos AV, Sprong D, Nunn AD, Balm AJ, Hoefnagel CA, Begg AC, Haustermans KM. Phase 1 study to identify tumour hypoxia in patients with head and neck cancer using technetium-99m BRU 59-21. Eur J Nucl Med Mol Imaging. 2002 Sep; 29(9):1206-11. PMID: 12192567.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  122. Hoebers FJ, Borger JH, Hart AA, Peterse JL, Th EJ, Lebesque JV. Primary axillary radiotherapy as axillary treatment in breast-conserving therapy for patients with breast carcinoma and clinically negative axillary lymph nodes. Cancer. 2000 Apr 01; 88(7):1633-42. PMID: 10738222.
    Citations: 9     Fields:    Translation:Humans
  123. van de Heijning BJ, van de Meeberg PC, Portincasa P, Doornewaard H, Hoebers FJ, van Erpecum KJ, Vanberge-Henegouwen GP. Effects of ursodeoxycholic acid therapy on in vitro gallbladder contractility in patients with cholesterol gallstones. Dig Dis Sci. 1999 Jan; 44(1):190-6. PMID: 9952243.
    Citations: 11     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.