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Levent Akyurek, Ph.D.

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Biography
Sahlgrenska Academy Hospital, SwedenConsultant Pathologist2019Clinical pathology
University of Gothenburg, SwedenProfessor2014Molecular pathology
NIH/NHLBI, USAPostdoc2002Vascular biology
University of Michigan, USAPostdoc1999Vascular biology
Uppsala University, SwedenPhD1996Transplantation immunology
Dokuz Eylül University, TurkeyMD1989Medicine

Overview

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Eklund EA, Wiel C, Fagman H, Akyürek LM, Raghavan S, Nyman J, Hallqvist A, Sayin VI. KRAS Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer. Cancers (Basel). 2022 Apr 20; 14(9). PMID: 35565194.
    Citations:    
  2. Bandaru S, Prajapati B, Juvvuna PK, Dosa S, Kogner P, Johnsen JI, Kanduri C, Akyürek LM. Filamin A increases aggressiveness of human neuroblastoma. Neurooncol Adv. 2022; 4(1):vdac028. PMID: 35441138.
    Citations:    
  3. Johansson I, Levin M, Akyürek LM, Olofsson Bagge R, Ny L. PD-1 inhibitor therapy of basal cell carcinoma with pulmonary metastasis. J Eur Acad Dermatol Venereol. 2022 Jan; 36 Suppl 1:70-73. PMID: 34855248.
    Citations:    
  4. Bandaru S, Ala C, Zhou AX, Akyürek LM. Filamin A Regulates Cardiovascular Remodeling. Int J Mol Sci. 2021 Jun 18; 22(12). PMID: 34207234.
    Citations:    
  5. Bandaru S, Ala C, Ekstrand M, Akula MK, Pedrelli M, Liu X, Bergström G, Håversen L, Borén J, Bergo MO, Akyürek LM. Lack of RAC1 in macrophages protects against atherosclerosis. PLoS One. 2020; 15(9):e0239284. PMID: 32941503.
    Citations:    
  6. Akyürek LM, Hussein A, Nicholson AG, Mauritz NJ, Mölne J. Pulmonary manifestations of systemic karyomegaly. Respir Med Case Rep. 2020; 29:101032. PMID: 32154101.
    Citations:    
  7. Bandaru S, Ala C, Salimi R, Akula MK, Ekstrand M, Devarakonda S, Karlsson J, Van den Eynden J, Bergström G, Larsson E, Levin M, Borén J, Bergo MO, Akyürek LM. Targeting Filamin A Reduces Macrophage Activity and Atherosclerosis. Circulation. 2019 Jul 02; 140(1):67-79. PMID: 31014088.
    Citations:    
  8. Salimi R, Bandaru S, Devarakonda S, Gökalp S, Ala C, Alvandian A, Yener N, Akyürek LM. Blocking the Cleavage of Filamin A by Calpain Inhibitor Decreases Tumor Cell Growth. Anticancer Res. 2018 Apr; 38(4):2079-2085. PMID: 29599325.
    Citations:    
  9. Mondal T, Juvvuna PK, Kirkeby A, Mitra S, Kosalai ST, Traxler L, Hertwig F, Wernig-Zorc S, Miranda C, Deland L, Volland R, Bartenhagen C, Bartsch D, Bandaru S, Engesser A, Subhash S, Martinsson T, Carén H, Akyürek LM, Kurian L, Kanduri M, Huarte M, Kogner P, Fischer M, Kanduri C. Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis. Cancer Cell. 2018 Mar 12; 33(3):417-434.e7. PMID: 29533783.
    Citations:    
  10. Pandey GK, Mitra S, Subhash S, Hertwig F, Kanduri M, Mishra K, Fransson S, Ganeshram A, Mondal T, Bandaru S, Ostensson M, Akyürek LM, Abrahamsson J, Pfeifer S, Larsson E, Shi L, Peng Z, Fischer M, Martinsson T, Hedborg F, Kogner P, Kanduri C. The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation. Cancer Cell. 2014 Nov 10; 26(5):722-37. PMID: 25517750.
    Citations:    
  11. Bandaru S, Grönros J, Redfors B, Çil Ç, Pazooki D, Salimi R, Larsson E, Zhou AX, Ömerovic E, Akyürek LM. Deficiency of filamin A in endothelial cells impairs left ventricular remodelling after myocardial infarction. Cardiovasc Res. 2015 Feb 01; 105(2):151-9. PMID: 25344364.
    Citations:    
  12. Bandaru S, Zhou AX, Rouhi P, Zhang Y, Bergo MO, Cao Y, Akyürek LM. Targeting filamin B induces tumor growth and metastasis via enhanced activity of matrix metalloproteinase-9 and secretion of VEGF-A. Oncogenesis. 2014 Sep 22; 3(9):e119. PMID: 25244493.
    Citations:    
  13. Zheng X, Zhou AX, Rouhi P, Uramoto H, Borén J, Cao Y, Pereira T, Akyürek LM, Poellinger L. Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2560-5. PMID: 24550283.
    Citations:    
  14. Nallapalli RK, Ibrahim MX, Zhou AX, Bandaru S, Sunkara SN, Redfors B, Pazooki D, Zhang Y, Borén J, Cao Y, Bergo MO, Akyürek LM. Targeting filamin A reduces K-RAS-induced lung adenocarcinomas and endothelial response to tumor growth in mice. Mol Cancer. 2012 Aug 02; 11:50. PMID: 22857000.
    Citations:    
  15. Zhou AX, Toylu A, Nallapalli RK, Nilsson G, Atabey N, Heldin CH, Borén J, Bergo MO, Akyürek LM. Filamin a mediates HGF/c-MET signaling in tumor cell migration. Int J Cancer. 2011 Feb 15; 128(4):839-46. PMID: 20473907.
    Citations:    
  16. Uramoto H, Akyürek LM, Hanagiri T. A positive relationship between filamin and VEGF in patients with lung cancer. Anticancer Res. 2010 Oct; 30(10):3939-44. PMID: 21036706.
    Citations:    
  17. Zhou AX, Hartwig JH, Akyürek LM. Filamins in cell signaling, transcription and organ development. Trends Cell Biol. 2010 Feb; 20(2):113-23. PMID: 20061151.
    Citations: 137     Fields:    Translation:HumansAnimalsCells
  18. Zhou X, Borén J, Akyürek LM. Filamins in cardiovascular development. Trends Cardiovasc Med. 2007 Oct; 17(7):222-9. PMID: 17936203.
    Citations:    
  19. Zhou X, Tian F, Sandzén J, Cao R, Flaberg E, Szekely L, Cao Y, Ohlsson C, Bergo MO, Borén J, Akyürek LM. Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):3919-24. PMID: 17360453.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.