Harvard Catalyst Profiles

Peter MacCallum Cancer Centre & University of Melbourne, Melbourne, Australia	PhD	2021	Hematology/Oncology, Cancer Biology
University of Melbourne, Melbourne, Australia	BSc (Hons)	2016	Pathology

I am a Research Fellow in Pediatrics in the Department of Pediatric Oncology at Dana-Farber Cancer Institute, with co-appointments at Harvard Medical School and The Broad Institute of MIT and Harvard, based in Boston, MA. My research is centered on pediatric hematological malignancies, and the discovery of new cancer targets and small-molecule therapeutic leads in the laboratory of Professor Kimberly Stegmaier (Vice Chair of Pediatric Oncology Research and Co-Director, Pediatric Hematologic Malignancy Program, Dana-Farber Cancer Institute and Boston Children's Hospital).

I received my doctorate under the mentorship of Professor Ricky Johnstone (Executive Director of Cancer Research) and Dr Gareth Gregory at the Peter MacCallum Cancer Centre and The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Australia. My doctoral work focussed on dissecting metabolic rewiring mediated by FLT3-ITD, one of the most common mutations in acute myeloid leukemia (AML), and uncovered a targetable dependency in this aggressive subset of AML. This work was published in the top journal Cancer Discovery in 2021.

My postdoctoral work builds on my previous training by extending my expertise in AML model generation and characterization, large-scale genetic screening, transcription, epigenetics, cellular metabolism, and use of in vivo models for therapeutic validation.

• Hematological Malignancies
• Acute Myeloid Leukemia
• Pediatrics
• Cancer Metabolism
• Epigenetics