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Marco Losa, Ph.D., M.D.

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selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Pecori Giraldi F, Cassarino MF, Sesta A, Lasio G, Losa M. SILIBININ, AN HSP90 INHIBITOR, ON HUMAN ACTH-SECRETING ADENOMAS. Neuroendocrinology. 2023 Feb 15. PMID: 36791678.
    Citations:    Fields:    
  2. Albano L, Losa M, Barzaghi LR, Mortini P. Letter to the Editor. Management of residual nonfunctioning pituitary adenoma: watchful waiting or adjuvant treatment? J Neurosurg. 2023 Feb 10; 1-2. PMID: 36789988.
    Citations:    Fields:    
  3. Schürch PM, Malinovska L, Hleihil M, Losa M, Hofstetter MC, Wildschut MHE, Lysenko V, Lakkaraju AKK, Maat CA, Benke D, Aguzzi A, Wollscheid B, Picotti P, Theocharides APA. Calreticulin mutations affect its chaperone function and perturb the glycoproteome. Cell Rep. 2022 11 22; 41(8):111689. PMID: 36417879.
    Citations:    Fields:    Translation:Humans
  4. Avar M, Heinzer D, Thackray AM, Liu Y, Hruska-Plochan M, Sellitto S, Schaper E, Pease DP, Yin JA, Lakkaraju AK, Emmenegger M, Losa M, Chincisan A, Hornemann S, Polymenidou M, Bujdoso R, Aguzzi A. An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation. EMBO J. 2022 12 01; 41(23):e112338. PMID: 36254605; PMCID: PMC9713719.
    Citations: 1     Fields:    Translation:Animals
  5. Detomas M, Ritzel K, Nasi-Kordhishti I, Wolfsberger S, Quinkler M, Losa M, Tröger V, Kroiss M, Fassnacht M, Vila G, Honegger JB, Reincke M, Deutschbein T. Outcome of CRH stimulation test and overnight 8 mg dexamethasone suppression test in 469 patients with ACTH-dependent Cushing's syndrome. Front Endocrinol (Lausanne). 2022; 13:955945. PMID: 36277711; PMCID: PMC9583401.
    Citations:    Fields:    Translation:Humans
  6. Losa M, Albano L, Bailo M, Barzaghi LR, Mortini P. Role of radiosurgery in the treatment of Cushing's disease. J Neuroendocrinol. 2022 08; 34(8):e13134. PMID: 35980263.
    Citations: 5     Fields:    Translation:Humans
  7. Frontzek K, Bardelli M, Senatore A, Henzi A, Reimann RR, Bedir S, Marino M, Hussain R, Jurt S, Meisl G, Pedotti M, Mazzola F, Siligardi G, Zerbe O, Losa M, Knowles T, Lakkaraju A, Zhu C, Schwarz P, Hornemann S, Holt MG, Simonelli L, Varani L, Aguzzi A. A conformational switch controlling the toxicity of the prion protein. Nat Struct Mol Biol. 2022 08; 29(8):831-840. PMID: 35948768; PMCID: PMC9371974.
    Citations: 3     Fields:    Translation:Animals
  8. Frara S, Melin Uygur M, di Filippo L, Doga M, Losa M, Santoro S, Mortini P, Giustina A. High Prevalence of Vertebral Fractures Associated With Preoperative GH Levels in Patients With Recent Diagnosis of Acromegaly. J Clin Endocrinol Metab. 2022 06 16; 107(7):e2843-e2850. PMID: 35349698.
    Citations: 3     Fields:    Translation:Humans
  9. Mortini P, Albano L, Barzaghi LR, Losa M. Pituitary Surgery. Presse Med. 2021 Dec; 50(4):104079. PMID: 34687913.
    Citations: 1     Fields:    Translation:Humans
  10. Albano L, Losa M, Barzaghi LR, Niranjan A, Siddiqui Z, Flickinger JC, Lunsford LD, Mortini P. Gamma Knife Radiosurgery for Pituitary Tumors: A Systematic Review and Meta-Analysis. Cancers (Basel). 2021 Oct 05; 13(19). PMID: 34638482; PMCID: PMC8508565.
    Citations: 3     
  11. Lakkaraju AKK, Frontzek K, Lemes E, Herrmann U, Losa M, Marpakwar R, Aguzzi A. Loss of PIKfyve drives the spongiform degeneration in prion diseases. EMBO Mol Med. 2021 09 07; 13(9):e14714. PMID: 34291577; PMCID: PMC8518562.
    Citations: 4     Fields:    Translation:AnimalsCells
  12. Mortini P, Albano L, Barzaghi LR, Spina A, Losa M. The open sella technique for surgical treatment of pituitary macroadenomas: Safety and efficacy in a large clinical series. Br J Neurosurg. 2021 Jul 16; 1-8. PMID: 34269154.
    Citations: 1     Fields:    
  13. Gallotti AL, Barzaghi LR, Albano L, Medone M, Gagliardi F, Losa M, Mortini P. Comparison between extended transsphenoidal and transcranial surgery for craniopharyngioma: focus on hypothalamic function and obesity. Pituitary. 2022 Feb; 25(1):74-84. PMID: 34236593.
    Citations: 3     Fields:    Translation:Humans
  14. Losa M, Resmini E, Barzaghi LR, Albano L, Bailo M, Webb SM, Mortini P. Resistance to first-generation somatostatin receptor ligands does not impair the results of gamma knife radiosurgery in acromegaly. Clin Endocrinol (Oxf). 2021 12; 95(6):849-855. PMID: 34219264.
    Citations: 1     Fields:    Translation:Humans
  15. Kara E, Crimi A, Wiedmer A, Emmenegger M, Manzoni C, Bandres-Ciga S, D'Sa K, Reynolds RH, Botía JA, Losa M, Lysenko V, Carta M, Heinzer D, Avar M, Chincisan A, Blauwendraat C, García-Ruiz S, Pease D, Mottier L, Carrella A, Beck-Schneider D, Magalhães AD, Aemisegger C, Theocharides APA, Fan Z, Marks JD, Hopp SC, Abramov AY, Lewis PA, Ryten M, Hardy J, Hyman BT, Aguzzi A. An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of a-synuclein. Cell Rep. 2021 06 08; 35(10):109189. PMID: 34107263; PMCID: PMC8207177.
    Citations: 3     Fields:    Translation:Humans
  16. Reincke M, Albani A, Assie G, Bancos I, Brue T, Buchfelder M, Chabre O, Ceccato F, Daniele A, Detomas M, Di Dalmazi G, Elenkova A, Findling J, Grossman AB, Gomez-Sanchez CE, Heaney AP, Honegger J, Karavitaki N, Lacroix A, Laws ER, Losa M, Murakami M, Newell-Price J, Pecori Giraldi F, Pérez-Rivas LG, Pivonello R, Rainey WE, Sbiera S, Schopohl J, Stratakis CA, Theodoropoulou M, van Rossum EFC, Valassi E, Zacharieva S, Rubinstein G, Ritzel K. Corticotroph tumor progression after bilateral adrenalectomy (Nelson's syndrome): systematic review and expert consensus recommendations. Eur J Endocrinol. 2021 Mar; 184(3):P1-P16. PMID: 33444221; PMCID: PMC8060870.
    Citations: 12     Fields:    Translation:Humans
  17. Mortini P, Nocera G, Roncelli F, Losa M, Formenti AM, Giustina A. The optimal numerosity of the referral population of pituitary tumors centers of excellence (PTCOE): A surgical perspective. Rev Endocr Metab Disord. 2020 Dec; 21(4):527-536. PMID: 32488741.
    Citations: 10     Fields:    Translation:Humans
  18. Stalla GK, Arzt E, Losa M, Renner U. Editorial: Current Clinical and Pre-Clinical Progress in Cushing's Disease. Front Endocrinol (Lausanne). 2020; 11:612321. PMID: 33329407; PMCID: PMC7718004.
    Citations:    Fields:    Translation:HumansAnimals
  19. Giustina A, Barkhoudarian G, Beckers A, Ben-Shlomo A, Biermasz N, Biller B, Boguszewski C, Bolanowski M, Bollerslev J, Bonert V, Bronstein MD, Buchfelder M, Casanueva F, Chanson P, Clemmons D, Fleseriu M, Formenti AM, Freda P, Gadelha M, Geer E, Gurnell M, Heaney AP, Ho KKY, Ioachimescu AG, Lamberts S, Laws E, Losa M, Maffei P, Mamelak A, Mercado M, Molitch M, Mortini P, Pereira AM, Petersenn S, Post K, Puig-Domingo M, Salvatori R, Samson SL, Shimon I, Strasburger C, Swearingen B, Trainer P, Vance ML, Wass J, Wierman ME, Yuen KCJ, Zatelli MC, Melmed S. Multidisciplinary management of acromegaly: A consensus. Rev Endocr Metab Disord. 2020 12; 21(4):667-678. PMID: 32914330.
    Citations: 64     Fields:    Translation:Humans
  20. Losa M, Garbin E, Pedone E, Mortini P. Normal Insulin-like Growth Factor 1 During Somatostatin Receptor Ligand Treatment Predicts Surgical Cure in Acromegaly. J Clin Endocrinol Metab. 2020 09 01; 105(9). PMID: 32609842.
    Citations:    Fields:    Translation:Humans
  21. Senatore A, Frontzek K, Emmenegger M, Chincisan A, Losa M, Reimann R, Horny G, Guo J, Fels S, Sorce S, Zhu C, George N, Ewert S, Pietzonka T, Hornemann S, Aguzzi A. Protective anti-prion antibodies in human immunoglobulin repertoires. EMBO Mol Med. 2020 09 07; 12(9):e12739. PMID: 32776637; PMCID: PMC7506995.
    Citations: 7     Fields:    Translation:HumansCells
  22. Losa M, Castellino L, Pagnano A, Rossini A, Mortini P, Lanzi R. Growth Hormone Therapy Does Not Increase the Risk of Craniopharyngioma and Nonfunctioning Pituitary Adenoma Recurrence. J Clin Endocrinol Metab. 2020 05 01; 105(5). PMID: 32112101.
    Citations: 8     Fields:    Translation:Humans
  23. Giustina A, Barkan A, Beckers A, Biermasz N, Biller BMK, Boguszewski C, Bolanowski M, Bonert V, Bronstein MD, Casanueva FF, Clemmons D, Colao A, Ferone D, Fleseriu M, Frara S, Gadelha MR, Ghigo E, Gurnell M, Heaney AP, Ho K, Ioachimescu A, Katznelson L, Kelestimur F, Kopchick J, Krsek M, Lamberts S, Losa M, Luger A, Maffei P, Marazuela M, Mazziotti G, Mercado M, Mortini P, Neggers S, Pereira AM, Petersenn S, Puig-Domingo M, Salvatori R, Shimon I, Strasburger C, Tsagarakis S, van der Lely AJ, Wass J, Zatelli MC, Melmed S. A Consensus on the Diagnosis and Treatment of Acromegaly Comorbidities: An Update. J Clin Endocrinol Metab. 2020 04 01; 105(4). PMID: 31606735.
    Citations: 56     Fields:    Translation:Humans
  24. Pecori Giraldi F, Cassarino MF, Sesta A, Terreni M, Lasio G, Losa M. Sexual Dimorphism in Cellular and Molecular Features in Human ACTH-Secreting Pituitary Adenomas. Cancers (Basel). 2020 Mar 13; 12(3). PMID: 32183012; PMCID: PMC7139870.
    Citations: 3     
  25. Albano L, Losa M, Flickinger J, Mortini P, Minniti G. Radiotherapy of Parasellar Tumours. Neuroendocrinology. 2020; 110(9-10):848-858. PMID: 32126559.
    Citations: 6     Fields:    Translation:Humans
  26. Rubinstein G, Osswald A, Hoster E, Losa M, Elenkova A, Zacharieva S, Machado MC, Hanzu FA, Zopp S, Ritzel K, Riester A, Braun LT, Kreitschmann-Andermahr I, Storr HL, Bansal P, Barahona MJ, Cosaro E, Dogansen SC, Johnston PC, Santos de Oliveira R, Raftopoulos C, Scaroni C, Valassi E, van der Werff SJA, Schopohl J, Beuschlein F, Reincke M. Time to Diagnosis in Cushing's Syndrome: A Meta-Analysis Based on 5367 Patients. J Clin Endocrinol Metab. 2020 03 01; 105(3). PMID: 31665382.
    Citations: 17     Fields:    Translation:Humans
  27. Frontzek K, Carta M, Losa M, Epskamp M, Meisl G, Anane A, Brandel JP, Camenisch U, Castilla J, Haïk S, Knowles T, Lindner E, Lutterotti A, Minikel EV, Roiter I, Safar JG, Sanchez-Valle R, Žáková D, Hornemann S, Aguzzi A. Autoantibodies against the prion protein in individuals with PRNP mutations. Neurology. 2020 10 06; 95(14):e2028-e2037. PMID: 32098855; PMCID: PMC7682844.
    Citations: 4     Fields:    Translation:Humans
  28. Sesta A, Cassarino MF, Terreni M, Ambrogio AG, Libera L, Bardelli D, Lasio G, Losa M, Pecori Giraldi F. Ubiquitin-Specific Protease 8 Mutant Corticotrope Adenomas Present Unique Secretory and Molecular Features and Shed Light on the Role of Ubiquitylation on ACTH Processing. Neuroendocrinology. 2020; 110(1-2):119-129. PMID: 31280266; PMCID: PMC6979434.
    Citations: 12     Fields:    Translation:HumansCells
  29. Albano L, Losa M, Spatola G, Panni P, Terreni MR, Barzaghi LR, Mortini P. Primary sellar melanocytoma: report of two cases treated at the same institution and their long-term outcome. Br J Neurosurg. 2019 Sep 20; 1-5. PMID: 31538490.
    Citations: 3     Fields:    
  30. Barzaghi LR, Losa M, Capitanio JF, Albano L, Weber G, Mortini P. Pediatric Pituitary Adenomas: Early and Long-Term Surgical Outcome in a Series of 85 Consecutive Patients. Neurosurgery. 2019 07 01; 85(1):65-74. PMID: 29790934.
    Citations: 8     Fields:    Translation:Humans
  31. Spina A, Losa M, Mortini P. Pituitary adenomas in elderly patients: clinical and surgical outcome analysis in a large series. Endocrine. 2019 09; 65(3):637-645. PMID: 31209675.
    Citations: 10     Fields:    Translation:Humans
  32. Losa M, Donofrio CA, Gemma M, Barzaghi LR, Mortini P. Pretreatment with somatostatin analogs does not affect the anesthesiologic management of patients with acromegaly. Pituitary. 2019 Apr; 22(2):187-194. PMID: 30826981.
    Citations: 3     Fields:    Translation:Humans
  33. Scaroni C, Albiger N, Daniele A, Dassie F, Romualdi C, Vazza G, Regazzo D, Ferraù F, Barresi V, Maffeis V, Gardiman MP, Cannavò S, Maffei P, Ceccato F, Losa M, Occhi G. Paradoxical GH Increase During OGTT Is Associated With First-Generation Somatostatin Analog Responsiveness in Acromegaly. J Clin Endocrinol Metab. 2019 03 01; 104(3):856-862. PMID: 30285115.
    Citations: 7     Fields:    Translation:Humans
  34. Albano L, Losa M, Nadin F, Barzaghi LR, Parisi V, Del Vecchio A, Bolognesi A, Mortini P. Safety and efficacy of multisession gamma knife radiosurgery for residual or recurrent pituitary adenomas. Endocrine. 2019 06; 64(3):639-647. PMID: 30798432.
    Citations: 6     Fields:    Translation:Humans
  35. Albano L, Parisi V, Acerno S, Barzaghi LR, Losa M, Mortini P. Sublabial transsphenoidal microsurgical technique to treat congenital transsphenoidal encephalocele: a technical note. Neurosurg Rev. 2019 Jun; 42(2):571-575. PMID: 30607614.
    Citations: 2     Fields:    Translation:Humans
  36. Losa M, Carta MC, Frontzek K, Krayenbühl N, Wichmann W, Rushing EJ. An Infratentorial Tumor in a 44-Year-Old Female Patient. Brain Pathol. 2019 01; 29(1):145-146. PMID: 30600598; PMCID: PMC8028633.
    Citations:    Fields:    Translation:Humans
  37. Losa M, Mortini P, Pagnano A, Detomas M, Cassarino MF, Pecori Giraldi F. Clinical characteristics and surgical outcome in USP8-mutated human adrenocorticotropic hormone-secreting pituitary adenomas. Endocrine. 2019 02; 63(2):240-246. PMID: 30315484.
    Citations: 19     Fields:    Translation:Humans
  38. Losa M, Pieri V, Bailo M, Gagliardi F, Barzaghi LR, Gioia L, Del Vecchio A, Bolognesi A, Mortini P. Single fraction and multisession Gamma Knife radiosurgery for craniopharyngioma. Pituitary. 2018 Oct; 21(5):499-506. PMID: 30043097.
    Citations: 7     Fields:    Translation:Humans
  39. Cassarino MF, Ambrogio AG, Cassarino A, Terreni MR, Gentilini D, Sesta A, Cavagnini F, Losa M, Pecori Giraldi F. Gene expression profiling in human corticotroph tumours reveals distinct, neuroendocrine profiles. J Neuroendocrinol. 2018 09; 30(9):e12628. PMID: 29920815; PMCID: PMC6175113.
    Citations: 13     Fields:    Translation:Humans
  40. Frara S, Losa M, Doga M, Formenti AM, Mortini P, Mazziotti G, Giustina A. High Prevalence of Radiological Vertebral Fractures in Patients With TSH-Secreting Pituitary Adenoma. J Endocr Soc. 2018 Sep 01; 2(9):1089-1099. PMID: 30202830; PMCID: PMC6125713.
    Citations: 6     
  41. Barzaghi LR, Donofrio CA, Panni P, Losa M, Mortini P. Treatment of empty sella associated with visual impairment: a systematic review of chiasmapexy techniques. Pituitary. 2018 Feb; 21(1):98-106. PMID: 29027644.
    Citations: 6     Fields:    Translation:HumansCells
  42. Alongi P, Iaccarino L, Losa M, Del Vecchio A, Gerevini S, Plebani V, Di Muzio N, Mortini P, Gianolli L, Perani D. PET Evaluation of Late Cerebral Effect in Advanced Radiation Therapy Techniques for Cranial Base Tumors. Curr Radiopharm. 2018; 11(2):86-91. PMID: 29804540.
    Citations:    Fields:    Translation:Humans
  43. Mortini P, Barzaghi LR, Albano L, Panni P, Losa M. Microsurgical therapy of pituitary adenomas. Endocrine. 2018 01; 59(1):72-81. PMID: 29067608.
    Citations: 21     Fields:    Translation:Humans
  44. Caretto A, Lanzi R, Piani C, Molgora M, Mortini P, Losa M. Ovarian hyperstimulation syndrome due to follicle-stimulating hormone-secreting pituitary adenomas. Pituitary. 2017 Oct; 20(5):553-560. PMID: 28676954.
    Citations: 10     Fields:    Translation:Humans
  45. Aiello A, Cassarino MF, Nanni S, Sesta A, Ferraú F, Grassi C, Losa M, Trimarchi F, Pontecorvi A, Cannavò S, Pecori Giraldi F, Farsetti A. Establishment of a protocol to extend the lifespan of human hormone-secreting pituitary adenoma cells. Endocrine. 2018 01; 59(1):102-108. PMID: 28447256.
    Citations: 2     Fields:    Translation:HumansCells
  46. Donofrio CA, Losa M, Gemma M, Giudice L, Barzaghi LR, Mortini P. Safety of transsphenoidal microsurgical approach in patients with an ACTH-secreting pituitary adenoma. Endocrine. 2017 Nov; 58(2):303-311. PMID: 28005257.
    Citations: 7     Fields:    Translation:Humans
  47. Mariotti S, Losa M, Mortini P, Saba L. The birth and rise of a craniopharyngioma: the radiological evolution of an incidental craniopharyngioma detected on serial MRI during medical treatment of a macroprolactinoma. Clin Case Rep. 2017 Jan; 5(1):14-17. PMID: 28096982; PMCID: PMC5224775.
    Citations:    
  48. Losa M, Spatola G, Albano L, Gandolfi A, Del Vecchio A, Bolognesi A, Mortini P. Frequency, pattern, and outcome of recurrences after gamma knife radiosurgery for pituitary adenomas. Endocrine. 2017 Jun; 56(3):595-602. PMID: 27688011.
    Citations: 15     Fields:    Translation:Humans
  49. Mortini P, Gagliardi F, Bailo M, Boari N, Castellano A, Falini A, Losa M. Resection of tumors of the third ventricle involving the hypothalamus: effects on body mass index using a dedicated surgical approach. Endocrine. 2017 Jul; 57(1):138-147. PMID: 27688008.
    Citations: 3     Fields:    Translation:Humans
  50. Spatola G, Frosio L, Losa M, Del Vecchio A, Piloni M, Mortini P. Asymptomatic internal carotid artery occlusion after gamma knife radiosurgery for pituitary adenoma: Report of two cases and review of the literature. Rep Pract Oncol Radiother. 2016 Nov-Dec; 21(6):555-559. PMID: 27721669; PMCID: PMC5045960.
    Citations: 3     
  51. Gagliardi F, Spina A, Barzaghi LR, Bailo M, Losa M, Terreni MR, Mortini P. Suprasellar granular cell tumor of the neurohypophysis: surgical outcome of a very rare tumor. Pituitary. 2016 Jun; 19(3):277-85. PMID: 26753850.
    Citations: 5     Fields:    Translation:Humans
  52. Cassarino MF, Sesta A, Pagliardini L, Losa M, Lasio G, Cavagnini F, Pecori Giraldi F. Proopiomelanocortin, glucocorticoid, and CRH receptor expression in human ACTH-secreting pituitary adenomas. Endocrine. 2017 Mar; 55(3):853-860. PMID: 27220856; PMCID: PMC5316398.
    Citations: 8     Fields:    Translation:HumansCells
  53. Mortini P, Gagliardi F, Bailo M, Spina A, Parlangeli A, Falini A, Losa M. Magnetic resonance imaging as predictor of functional outcome in craniopharyngiomas. Endocrine. 2016 Jan; 51(1):148-62. PMID: 26179178.
    Citations: 15     Fields:    Translation:Humans
  54. Perticone F, Pigliaru F, Mariotti S, Deiana L, Furlani L, Mortini P, Losa M. Is the incidence of differentiated thyroid cancer increased in patients with thyrotropin-secreting adenomas? Report of three cases from a large consecutive series. Thyroid. 2015 Apr; 25(4):417-24. PMID: 25647054.
    Citations: 7     Fields:    Translation:Humans
  55. Cassarino MF, Sesta A, Pagliardini L, Losa M, Lasio G, Cavagnini F, Pecori Giraldi F. AZA-deoxycytidine stimulates proopiomelanocortin gene expression and ACTH secretion in human pituitary ACTH-secreting tumors. Pituitary. 2014 Oct; 17(5):464-9. PMID: 24085685.
    Citations: 3     Fields:    Translation:HumansCells
  56. Malchiodi E, Profka E, Ferrante E, Sala E, Verrua E, Campi I, Lania AG, Arosio M, Locatelli M, Mortini P, Losa M, Motti E, Beck-Peccoz P, Spada A, Mantovani G. Thyrotropin-secreting pituitary adenomas: outcome of pituitary surgery and irradiation. J Clin Endocrinol Metab. 2014 Jun; 99(6):2069-76. PMID: 24552222.
    Citations: 18     Fields:    Translation:Humans
  57. Losa M, Donofrio CA, Barzaghi R, Mortini P. Presentation and surgical results of incidentally discovered nonfunctioning pituitary adenomas: evidence for a better outcome independently of other patients' characteristics. Eur J Endocrinol. 2013 Dec; 169(6):735-42. PMID: 23999643.
    Citations: 16     Fields:    Translation:Humans
  58. Gagliardi F, Losa M, Boari N, Spina A, Reni M, Terreni MR, Mortini P. Solitary clival plasmocytomas: Misleading clinical and radiological features of a rare pathology with a specific biological behaviour. Acta Neurochir (Wien). 2013 Oct; 155(10):1849-56. PMID: 23975648.
    Citations: 10     Fields:    Translation:Humans
  59. Mortini P, Gagliardi F, Boari N, Losa M. Surgical strategies and modern therapeutic options in the treatment of craniopharyngiomas. Crit Rev Oncol Hematol. 2013 Dec; 88(3):514-29. PMID: 23932582.
    Citations: 23     Fields:    Translation:Humans
  60. Gagliardi F, Losa M, Boari N, Franzin A, Pozzobon G, Weber G, Mortini P. Suprasellar granular cell tumor of the neurohypophysis in a child: unusual presentation in pediatric age of a rare tumor. Childs Nerv Syst. 2013 Jun; 29(6):1031-4. PMID: 23463129.
    Citations: 4     Fields:    Translation:Humans
  61. Tulipano G, Faggi L, Losa M, Mortini P, Spinello M, Sibilia V, Pagani F, Cocchi D, Giustina A. Effects of AMPK activation and combined treatment with AMPK activators and somatostatin on hormone secretion and cell growth in cultured GH-secreting pituitary tumor cells. Mol Cell Endocrinol. 2013 Jan 30; 365(2):197-206. PMID: 23116772.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  62. Sicignano G, Losa M, del Vecchio A, Cattaneo GM, Picozzi P, Bolognesi A, Mortini P, Calandrino R. Dosimetric factors associated with pituitary function after Gamma Knife Surgery (GKS) of pituitary adenomas. Radiother Oncol. 2012 Jul; 104(1):119-24. PMID: 22647658.
    Citations: 10     Fields:    Translation:Humans
  63. Ferraù F, Losa M, Cotta OR, Torre ML, Ragonese M, Trimarchi F, Cannavò S. Course of pregnancies in women with Cushing's disease treated by gamma-knife. Gynecol Endocrinol. 2012 Oct; 28(10):827-9. PMID: 22571755.
    Citations:    Fields:    Translation:Humans
  64. Franzin A, Spatola G, Losa M, Picozzi P, Mortini P. Results of gamma knife radiosurgery in acromegaly. Int J Endocrinol. 2012; 2012:342034. PMID: 22518119; PMCID: PMC3296167.
    Citations: 14     
  65. Mortini P, Barzaghi LR, Serra C, Orlandi V, Bianchi S, Losa M. Visual outcome after fronto-temporo-orbito-zygomatic approach combined with early extradural and intradural optic nerve decompression in tuberculum and diaphragma sellae meningiomas. Clin Neurol Neurosurg. 2012 Jul; 114(6):597-606. PMID: 22225973.
    Citations: 3     Fields:    Translation:Humans
  66. Barzaghi LR, Medone M, Losa M, Bianchi S, Giovanelli M, Mortini P. Prognostic factors of visual field improvement after trans-sphenoidal approach for pituitary macroadenomas: review of the literature and analysis by quantitative method. Neurosurg Rev. 2012 Jul; 35(3):369-78; discussion 378-9. PMID: 22080165.
    Citations: 26     Fields:    Translation:Humans
  67. Madaschi S, Sara M, Fiorino C, Claudio F, Losa M, Marco L, Lanzi R, Roberto L, Mazza E, Elena M, Motta M, Micaela M, Perna L, Lucia P, Brioschi E, Elena B, Scavini M, Marina S, Reni M, Michele R. Time course of hypothalamic-pituitary deficiency in adults receiving cranial radiotherapy for primary extrasellar brain tumors. Radiother Oncol. 2011 Apr; 99(1):23-8. PMID: 21458091.
    Citations: 9     Fields:    Translation:Humans
  68. Mortini P, Losa M, Pozzobon G, Barzaghi R, Riva M, Acerno S, Angius D, Weber G, Chiumello G, Giovanelli M. Neurosurgical treatment of craniopharyngioma in adults and children: early and long-term results in a large case series. J Neurosurg. 2011 May; 114(5):1350-9. PMID: 21214336.
    Citations: 59     Fields:    Translation:Humans
  69. Losa M, Mazza E, Terreni MR, McCormack A, Gill AJ, Motta M, Cangi MG, Talarico A, Mortini P, Reni M. Salvage therapy with temozolomide in patients with aggressive or metastatic pituitary adenomas: experience in six cases. Eur J Endocrinol. 2010 Dec; 163(6):843-51. PMID: 20870708.
    Citations: 38     Fields:    Translation:Humans
  70. Losa M, Picozzi P, Redaelli MG, Laurenzi A, Mortini P. Pituitary radiotherapy for Cushing's disease. Neuroendocrinology. 2010; 92 Suppl 1:107-10. PMID: 20829629.
    Citations: 8     Fields:    Translation:Humans
  71. Andrioli M, Pecori Giraldi F, Losa M, Terreni M, Invitti C, Cavagnini F. Cushing's disease due to double pituitary ACTH-secreting adenomas: the first case report. Endocr J. 2010; 57(9):833-7. PMID: 20595779.
    Citations: 9     Fields:    Translation:Humans
  72. Valassi E, Biller BM, Swearingen B, Pecori Giraldi F, Losa M, Mortini P, Hayden D, Cavagnini F, Klibanski A. Delayed remission after transsphenoidal surgery in patients with Cushing's disease. J Clin Endocrinol Metab. 2010 Feb; 95(2):601-10. PMID: 20080848; PMCID: PMC2840864.
    Citations: 36     Fields:    Translation:Humans
  73. Gagliardi F, Boari N, Losa M, Mortini P. Longitudinal splitting of optic pathways by non-functioning pituitary macroadenoma: report of two cases. Acta Neurochir (Wien). 2010 Jun; 152(6):1065-8; discussion 1068. PMID: 19826754.
    Citations: 1     Fields:    Translation:Humans
  74. Losa M, Bianchi R, Barzaghi R, Giovanelli M, Mortini P. Persistent adrenocorticotropin response to desmopressin in the early postoperative period predicts recurrence of Cushing's disease. J Clin Endocrinol Metab. 2009 Sep; 94(9):3322-8. PMID: 19584185.
    Citations: 11     Fields:    Translation:Humans
  75. Losa M, Gioia L, Picozzi P, Franzin A, Valle M, Giovanelli M, Mortini P. The role of stereotactic radiotherapy in patients with growth hormone-secreting pituitary adenoma. J Clin Endocrinol Metab. 2008 Jul; 93(7):2546-52. PMID: 18413424.
    Citations: 32     Fields:    Translation:Humans
  76. Losa M, Mortini P, Barzaghi R, Ribotto P, Terreni MR, Marzoli SB, Pieralli S, Giovanelli M. Early results of surgery in patients with nonfunctioning pituitary adenoma and analysis of the risk of tumor recurrence. J Neurosurg. 2008 Mar; 108(3):525-32. PMID: 18312100.
    Citations: 67     Fields:    Translation:Humans
  77. Mortini P, Barzaghi R, Losa M, Boari N, Giovanelli M. Surgical treatment of giant pituitary adenomas: strategies and results in a series of 95 consecutive patients. Neurosurgery. 2007 Jun; 60(6):993-1002; discussion 1003-4. PMID: 17538372.
    Citations: 53     Fields:    Translation:Humans
  78. Setola E, Losa M, Lanzi R, Lucotti P, Monti LD, Castrignanò T, Galluccio E, Giovanelli M, Piatti P. Increased insulin-stimulated endothelin-1 release is a distinct vascular phenotype distinguishing Cushing's disease from metabolic syndrome. Clin Endocrinol (Oxf). 2007 Apr; 66(4):586-92. PMID: 17371479.
    Citations: 8     Fields:    Translation:Humans
  79. Losa M, Mortini P, Urbaz L, Ribotto P, Castrignanó T, Giovanelli M. Presurgical treatment with somatostatin analogs in patients with acromegaly: effects on the remission and complication rates. J Neurosurg. 2006 Jun; 104(6):899-906. PMID: 16776333.
    Citations: 25     Fields:    Translation:Humans
  80. Scarone P, Losa M, Mortini P, Giovanelli M. Obstructive hydrocephalus and intracranial hypertension caused by a giant macroprolactinoma. Prompt response to medical treatment. J Neurooncol. 2006 Jan; 76(1):51-4. PMID: 16205966.
    Citations: 7     Fields:    Translation:Humans
  81. Vila G, Theodoropoulou M, Stalla J, Tonn JC, Losa M, Renner U, Stalla GK, Paez-Pereda M. Expression and function of sonic hedgehog pathway components in pituitary adenomas: evidence for a direct role in hormone secretion and cell proliferation. J Clin Endocrinol Metab. 2005 Dec; 90(12):6687-94. PMID: 16159933.
    Citations: 14     Fields:    Translation:HumansCells
  82. Mortini P, Losa M, Barzaghi R, Boari N, Giovanelli M. Results of transsphenoidal surgery in a large series of patients with pituitary adenoma. Neurosurgery. 2005 Jun; 56(6):1222-33; discussion 1233. PMID: 15918938.
    Citations: 80     Fields:    Translation:HumansCTClinical Trials
  83. Picozzi P, Losa M, Mortini P, Valle MA, Franzin A, Attuati L, Ferrari da Passano C, Giovanelli M. Radiosurgery and the prevention of regrowth of incompletely removed nonfunctioning pituitary adenomas. J Neurosurg. 2005 Jan; 102 Suppl:71-4. PMID: 15662784.
    Citations: 14     Fields:    Translation:Humans
  84. Losa M, Valle M, Mortini P, Franzin A, da Passano CF, Cenzato M, Bianchi S, Picozzi P, Giovanelli M. Gamma knife surgery for treatment of residual nonfunctioning pituitary adenomas after surgical debulking. J Neurosurg. 2004 Mar; 100(3):438-44. PMID: 15035279.
    Citations: 34     Fields:    Translation:Humans
  85. Pecori Giraldi F, Terreni MR, Andreotti C, Losa M, Lanzi R, Pontiroli AE, Cavagnini F. Meningioma presenting with Cushing's syndrome: an unusual clinical presentation. Ann Neurol. 2003 Jan; 53(1):138-42. PMID: 12509860.
    Citations: 5     Fields:    Translation:HumansCells
  86. Battezzati A, Benedini S, Fattorini A, Losa M, Mortini P, Bertoli S, Lanzi R, Testolin G, Biolo G, Luzi L. Insulin action on protein metabolism in acromegalic patients. Am J Physiol Endocrinol Metab. 2003 Apr; 284(4):E823-9. PMID: 12388147.
    Citations: 5     Fields:    Translation:Humans
  87. Losa M, Mortini P, Barzaghi R, Gioia L, Giovanelli M. Surgical treatment of prolactin-secreting pituitary adenomas: early results and long-term outcome. J Clin Endocrinol Metab. 2002 Jul; 87(7):3180-6. PMID: 12107221.
    Citations: 30     Fields:    Translation:Humans
  88. Finelli P, Pierantoni GM, Giardino D, Losa M, Rodeschini O, Fedele M, Valtorta E, Mortini P, Croce CM, Larizza L, Fusco A. The High Mobility Group A2 gene is amplified and overexpressed in human prolactinomas. Cancer Res. 2002 Apr 15; 62(8):2398-405. PMID: 11956103.
    Citations: 24     Fields:    Translation:Humans
  89. Gemma M, Tommasino C, Cozzi S, Narcisi S, Mortini P, Losa M, Soldarini A. Remifentanil provides hemodynamic stability and faster awakening time in transsphenoidal surgery. Anesth Analg. 2002 Jan; 94(1):163-8, table of contents. PMID: 11772821.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.