Harvard Catalyst Profiles

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Sirano Dhe-Paganon, Ph.D.

Co-Author

This page shows the publications co-authored by Sirano Dhe-Paganon and Hyuk Soo Seo.
Connection Strength

1.601
  1. Exploring Ligand-Directed N-Acyl-N-alkylsulfonamide-Based Acylation Chemistry for Potential Targeted Degrader Development. ACS Med Chem Lett. 2021 Aug 12; 12(8):1302-1307.
    View in: PubMed
    Score: 0.061
  2. Identification and validation of selective deubiquitinase inhibitors. Cell Chem Biol. 2021 Jun 02.
    View in: PubMed
    Score: 0.061
  3. Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity. bioRxiv. 2021 May 21.
    View in: PubMed
    Score: 0.061
  4. Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nat Chem Biol. 2021 09; 17(9):954-963.
    View in: PubMed
    Score: 0.061
  5. Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival. J Cell Biol. 2021 01 04; 220(1).
    View in: PubMed
    Score: 0.059
  6. Author Correction: The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma. Nat Struct Mol Biol. 2021 Jan; 28(1):118.
    View in: PubMed
    Score: 0.059
  7. Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy. Cell. 2020 11 25; 183(5):1219-1233.e18.
    View in: PubMed
    Score: 0.059
  8. The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma. Nat Struct Mol Biol. 2020 09; 27(9):836-845.
    View in: PubMed
    Score: 0.057
  9. Identification of a potent and selective covalent Pin1 inhibitor. Nat Chem Biol. 2020 09; 16(9):979-987.
    View in: PubMed
    Score: 0.057
  10. Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering. Cell Chem Biol. 2020 06 18; 27(6):647-656.e6.
    View in: PubMed
    Score: 0.057
  11. Glucose-dependent partitioning of arginine to the urea cycle protects ß-cells from inflammation. Nat Metab. 2020 05; 2(5):432-446.
    View in: PubMed
    Score: 0.057
  12. Identification of a Structural Determinant for Selective Targeting of HDMX. Structure. 2020 07 07; 28(7):847-857.e5.
    View in: PubMed
    Score: 0.056
  13. Discovery and Structure-Activity Relationship Study of (Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. J Med Chem. 2020 05 14; 63(9):4880-4895.
    View in: PubMed
    Score: 0.056
  14. Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors. Cell Chem Biol. 2020 05 21; 27(5):525-537.e6.
    View in: PubMed
    Score: 0.056
  15. Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell. 2019 11 27; 179(6):1342-1356.e23.
    View in: PubMed
    Score: 0.055
  16. Structural Implications of STAT3 and STAT5 SH2 Domain Mutations. Cancers (Basel). 2019 Nov 08; 11(11).
    View in: PubMed
    Score: 0.055
  17. Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. ACS Med Chem Lett. 2020 Mar 12; 11(3):346-352.
    View in: PubMed
    Score: 0.055
  18. Dual Inhibition of TAF1 and BET Bromodomains from the BI-2536 Kinase Inhibitor Scaffold. ACS Med Chem Lett. 2019 Oct 10; 10(10):1443-1449.
    View in: PubMed
    Score: 0.054
  19. Structural and functional consequences of the STAT5BN642H driver mutation. Nat Commun. 2019 06 07; 10(1):2517.
    View in: PubMed
    Score: 0.053
  20. Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells. Nat Commun. 2018 08 09; 9(1):3069.
    View in: PubMed
    Score: 0.050
  21. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands. Nat Chem Biol. 2018 04; 14(4):405-412.
    View in: PubMed
    Score: 0.049
  22. Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor. Structure. 2018 01 02; 26(1):153-160.e4.
    View in: PubMed
    Score: 0.048
  23. Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7. Cell Chem Biol. 2017 12 21; 24(12):1490-1500.e11.
    View in: PubMed
    Score: 0.047
  24. Inhibition of USP10 induces degradation of oncogenic FLT3. Nat Chem Biol. 2017 Dec; 13(12):1207-1215.
    View in: PubMed
    Score: 0.047
  25. MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife. 2017 09 19; 6.
    View in: PubMed
    Score: 0.047
  26. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands. Angew Chem Int Ed Engl. 2017 05 15; 56(21):5738-5743.
    View in: PubMed
    Score: 0.046
  27. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. 2017 03 09; 543(7644):270-274.
    View in: PubMed
    Score: 0.045
  28. p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma. Blood. 2017 03 09; 129(10):1308-1319.
    View in: PubMed
    Score: 0.045
  29. Leveraging Gas-Phase Fragmentation Pathways for Improved Identification and Selective Detection of Targets Modified by Covalent Probes. Anal Chem. 2016 12 20; 88(24):12248-12254.
    View in: PubMed
    Score: 0.045
  30. Design and characterization of bivalent BET inhibitors. Nat Chem Biol. 2016 Dec; 12(12):1089-1096.
    View in: PubMed
    Score: 0.044
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.