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profileAnand T.N. Kumar, Ph.D.

TitleAssistant Professor of Radiology
InstitutionMassachusetts General Hospital
DepartmentRadiology
AddressMassachusetts General Hospital
Martinos Center, Dept. of Radiology, Room 2301
149 13th Street
Charlestown MA 02129
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R01EB015325     (KUMAR, ANAND T.N.)Sep 15, 2011 - Aug 31, 2015
NIH/NIBIB
Fluorescence lifetime tomography of tumor physiology in small animals
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Steven S Hou, Brian J. Bacskai and Anand T. N. Kumar. Optimal estimator for tomographic fluorescence lifetime multiplexing. Optics Letters. 2016; 7(41):1352-1355.
  2. Rice WL, Shcherbakova DM, Verkhusha VV, Kumar AT. In vivo tomographic imaging of deep-seated cancer using fluorescence lifetime contrast. Cancer Res. 2015 Apr 1; 75(7):1236-43. PMID: 25670171; PMCID: PMC4383673 [Available on 04/01/16].
  3. Rice WL, Kumar AT. Preclinical whole body time domain fluorescence lifetime multiplexing of fluorescent proteins. J Biomed Opt. 2014 Apr; 19(4):046005. PMID: 24715027; PMCID: PMC3979168.
  4. Hou SS, Rice WL, Bacskai BJ, Kumar AT. Tomographic lifetime imaging using combined early- and late-arriving photons. Opt Lett. 2014 Mar 1; 39(5):1165-8. PMID: 24690697; PMCID: PMC4087160.
  5. Metelev V, Zhang S, Tabatadze D, Kumar AT, Bogdanov A. The three-dimensional context of a double helix determines the fluorescence of the internucleoside-tethered pair of fluorophores. Mol Biosyst. 2013 Oct; 9(10):2447-53. PMID: 23925269.
    View in: PubMed
  6. Rice WL, Hou S, Kumar AT. Resolution below the point spread function for diffuse optical imaging using fluorescence lifetime multiplexing. Opt Lett. 2013 Jun 15; 38(12):2038-40. PMID: 23938969; PMCID: PMC3992832.
  7. Kumar AT. Fluorescence lifetime detection in turbid media using spatial frequency domain filtering of time domain measurements. Opt Lett. 2013 May 1; 38(9):1440-2. PMID: 23632511; PMCID: PMC3732578.
  8. Kumar AT. Direct Monte Carlo computation of time-resolved fluorescence in heterogeneous turbid media. Opt Lett. 2012 Nov 15; 37(22):4783-5. PMID: 23164912; PMCID: PMC3544305.
  9. Guo Y, Yuan H, Rice WL, Kumar AT, Goergen CJ, Jokivarsi K, Josephson L. The PEG-fluorochrome shielding approach for targeted probe design. J Am Chem Soc. 2012 Nov 28; 134(47):19338-41. PMID: 23137147; PMCID: PMC3518033.
  10. Bogdanov AA, Metelev V, Zhang S, Kumar AT. Sensing of transcription factor binding via cyanine dye pair fluorescence lifetime changes. Mol Biosyst. 2012 Aug; 8(8):2166-73. PMID: 22710322.
    View in: PubMed
  11. Goergen CJ, Chen HH, Bogdanov A, Sosnovik DE, Kumar AT. In vivo fluorescence lifetime detection of an activatable probe in infarcted myocardium. J Biomed Opt. 2012 May; 17(5):056001. PMID: 22612124; PMCID: PMC3381023.
  12. Kumar AT. Fluorescence lifetime-based optical molecular imaging. Methods Mol Biol. 2011; 680:165-80. PMID: 21153381.
    View in: PubMed
  13. Raymond SB, Boas DA, Bacskai BJ, Kumar AT. Lifetime-based tomographic multiplexing. J Biomed Opt. 2010 Jul-Aug; 15(4):046011. PMID: 20799813; PMCID: PMC2929260.
  14. Kumar AT, Chung E, Raymond SB, van de Water JA, Shah K, Fukumura D, Jain RK, Bacskai BJ, Boas DA. Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast. Opt Lett. 2009 Jul 1; 34(13):2066-8. PMID: 19572001; PMCID: PMC2872111.
  15. Kumar AT, Raymond SB, Dunn AK, Bacskai BJ, Boas DA. A time domain fluorescence tomography system for small animal imaging. IEEE Trans Med Imaging. 2008 Aug; 27(8):1152-63. PMID: 18672432; PMCID: PMC2920137.
  16. Kumar AT, Raymond SB, Bacskai BJ, Boas DA. Comparison of frequency-domain and time-domain fluorescence lifetime tomography. Opt Lett. 2008 Mar 1; 33(5):470-2. PMID: 18311295; PMCID: PMC2913597.
  17. Kumar A, Haroon E, Darwin C, Pham D, Ajilore O, Rodriguez G, Mintz J. Gray matter prefrontal changes in type 2 diabetes detected using MRI. J Magn Reson Imaging. 2008 Jan; 27(1):14-9. PMID: 18050330.
    View in: PubMed
  18. Jones PB, Rozkalne A, Meyer-Luehmann M, Spires-Jones TL, Makarova A, Kumar AT, Berezovska O, Bacskai BB, Hyman BT. Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy. J Biomed Opt. 2008 Jan-Feb; 13(1):014008. PMID: 18315366.
    View in: PubMed
  19. Kumar AT, Raymond SB, Boverman G, Boas DA, Bacskai BJ. Time resolved fluorescence tomography of turbid media based on lifetime contrast. Opt Express. 2006 Dec 11; 14(25):12255-70. PMID: 19529654; PMCID: PMC2700299.
  20. Jones PB, Herl L, Berezovska O, Kumar AT, Bacskai BJ, Hyman BT. Time-domain fluorescent plate reader for cell based protein-protein interaction and protein conformation assays. J Biomed Opt. 2006 Sep-Oct; 11(5):054024. PMID: 17092173.
    View in: PubMed
  21. Kumar AT, Skoch J, Bacskai BJ, Boas DA, Dunn AK. Fluorescence-lifetime-based tomography for turbid media. Opt Lett. 2005 Dec 15; 30(24):3347-9. PMID: 16389827.
    View in: PubMed
  22. Kumar A, Gupta RC, Albert Thomas M, Alger J, Wyckoff N, Hwang S. Biophysical changes in normal-appearing white matter and subcortical nuclei in late-life major depression detected using magnetization transfer. Psychiatry Res. 2004 Feb 15; 130(2):131-40. PMID: 15033183.
    View in: PubMed
  23. Elderkin-Thompson V, Kumar A, Bilker WB, Dunkin JJ, Mintz J, Moberg PJ, Mesholam RI, Gur RE. Neuropsychological deficits among patients with late-onset minor and major depression. Arch Clin Neuropsychol. 2003 Jul; 18(5):529-49. PMID: 14591448.
    View in: PubMed
  24. Peleg M, Tu S, Bury J, Ciccarese P, Fox J, Greenes RA, Hall R, Johnson PD, Jones N, Kumar A, Miksch S, Quaglini S, Seyfang A, Shortliffe EH, Stefanelli M. Comparing computer-interpretable guideline models: a case-study approach. J Am Med Inform Assoc. 2003 Jan-Feb; 10(1):52-68. PMID: 12509357; PMCID: PMC150359.
  25. Kumar A, Thomas A, Lavretsky H, Yue K, Huda A, Curran J, Venkatraman T, Estanol L, Mintz J, Mega M, Toga A. Frontal white matter biochemical abnormalities in late-life major depression detected with proton magnetic resonance spectroscopy. Am J Psychiatry. 2002 Apr; 159(4):630-6. PMID: 11925302.
    View in: PubMed
  26. Kumar A, Mintz J, Bilker W, Gottlieb G. Autonomous neurobiological pathways to late-life major depressive disorder: clinical and pathophysiological implications. Neuropsychopharmacology. 2002 Feb; 26(2):229-36. PMID: 11790518.
    View in: PubMed
  27. Kumar A, Cook IA. White matter injury, neural connectivity and the pathophysiology of psychiatric disorders. Dev Neurosci. 2002; 24(4):255-61. PMID: 12457063.
    View in: PubMed
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