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profileKee-Hak Lim, M.D.

TitleAssociate Professor of Obstetrics, Gynecology and Reproductive Biology, Part-time
InstitutionBeth Israel Deaconess Medical Center
DepartmentObstetrics Gynecology & Repro. Bio.
AddressBeth Israel Deaconess Med Ctr
Ob/Gyn, KS 346
330 Brookline Ave
Boston MA 02215
Phone617/667-4507
Fax617/667-1459
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Easter SR, Cantonwine DE, Zera CA, Lim KH, Parry SI, McElrath TF. Urinary tract infection during pregnancy, angiogenic factor profiles, and risk of preeclampsia. Am J Obstet Gynecol. 2016 Mar; 214(3):387.e1-7. PMID: 26450405.
    View in: PubMed
  2. Lee MS, Cantonwine D, Little SE, McElrath TF, Parry SI, Lim KH, Wilkins-Haug LE. Angiogenic markers in pregnancies conceived through in vitro fertilization. Am J Obstet Gynecol. 2015 Aug; 213(2):212.e1-8. PMID: 25797229.
    View in: PubMed
  3. Faupel-Badger JM, McElrath TF, Lauria M, Houghton LC, Lim KH, Parry S, Cantonwine D, Lai G, Karumanchi SA, Hoover RN, Troisi R. Maternal circulating angiogenic factors in twin and singleton pregnancies. Am J Obstet Gynecol. 2015 May; 212(5):636.e1-8. PMID: 25434840; PMCID: PMC4416988.
  4. Paré E, Parry S, McElrath TF, Pucci D, Newton A, Lim KH. Clinical risk factors for preeclampsia in the 21st century. Obstet Gynecol. 2014 Oct; 124(4):763-70. PMID: 25198274.
    View in: PubMed
  5. Zera CA, Seely EW, Wilkins-Haug LE, Lim KH, Parry SI, McElrath TF. The association of body mass index with serum angiogenic markers in normal and abnormal pregnancies. Am J Obstet Gynecol. 2014 Sep; 211(3):247.e1-7. PMID: 24631439.
    View in: PubMed
  6. Cohen AL, Wenger JB, James-Todd T, Lamparello BM, Halprin E, Serdy S, Fan S, Horowitz GL, Lim KH, Rana S, Takoudes TC, Wyckoff JA, Thadhani R, Karumanchi SA, Brown FM. The association of circulating angiogenic factors and HbA1c with the risk of preeclampsia in women with preexisting diabetes. Hypertens Pregnancy. 2014 Feb; 33(1):81-92. PMID: 24354578; PMCID: PMC3894714.
  7. Rana S, Schnettler WT, Powe C, Wenger J, Salahuddin S, Cerdeira AS, Verlohren S, Perschel FH, Arany Z, Lim KH, Thadhani R, Karumanchi SA. Clinical characterization and outcomes of preeclampsia with normal angiogenic profile. Hypertens Pregnancy. 2013 May; 32(2):189-201. PMID: 23725084; PMCID: PMC3744824.
  8. Rana S, Cerdeira AS, Wenger J, Salahuddin S, Lim KH, Ralston SJ, Thadhani RI, Karumanchi SA. Plasma concentrations of soluble endoglin versus standard evaluation in patients with suspected preeclampsia. PLoS One. 2012; 7(10):e48259. PMID: 23110221; PMCID: PMC3482204.
  9. McElrath TF, Lim KH, Pare E, Rich-Edwards J, Pucci D, Troisi R, Parry S. Longitudinal evaluation of predictive value for preeclampsia of circulating angiogenic factors through pregnancy. Am J Obstet Gynecol. 2012 Nov; 207(5):407.e1-7. PMID: 22981320.
    View in: PubMed
  10. Rana S, Hacker MR, Modest AM, Salahuddin S, Lim KH, Verlohren S, Perschel FH, Karumanchi SA. Circulating angiogenic factors and risk of adverse maternal and perinatal outcomes in twin pregnancies with suspected preeclampsia. Hypertension. 2012 Aug; 60(2):451-8. PMID: 22753210; PMCID: PMC3432569.
  11. Rana S, Powe CE, Salahuddin S, Verlohren S, Perschel FH, Levine RJ, Lim KH, Wenger JB, Thadhani R, Karumanchi SA. Angiogenic factors and the risk of adverse outcomes in women with suspected preeclampsia. Circulation. 2012 Feb 21; 125(7):911-9. PMID: 22261192; PMCID: PMC3319742.
  12. Vadnais MA, Rana S, Quant HS, Salahuddin S, Dodge LE, Lim KH, Karumanchi SA, Hacker MR. The Impact of Magnesium Sulfate Therapy on Angiogenic Factors in Preeclampsia. Pregnancy Hypertens. 2012 Jan 01; 2(1):16-21. PMID: 22247820.
    View in: PubMed
  13. Bixel K, Silasi M, Zelop CM, Lim KH, Zsengeller Z, Stillman IE, Rana S. Placental origins of angiogenic dysfunction in mirror syndrome. Hypertens Pregnancy. 2012; 31(2):211-7. PMID: 22150085.
    View in: PubMed
  14. Silasi M, Rana S, Powe C, Cohen B, Lim KH, Zsengellér ZK, Karumanchi SA, Stillman IE. Placental expression of angiogenic factors in Trisomy 13. Am J Obstet Gynecol. 2011 Jun; 204(6):546.e1-4. PMID: 21507376.
    View in: PubMed
  15. Kasper EM, Hess PE, Silasi M, Lim KH, Gray J, Reddy H, Gilmore L, Kasper B. A pregnant female with a large intracranial mass: Reviewing the evidence to obtain management guidelines for intracranial meningiomas during pregnancy. Surg Neurol Int. 2010 Dec 25; 1:95. PMID: 21245945; PMCID: PMC3019368.
  16. Stefanic S, Dvorák J, Horn M, Braschi S, Sojka D, Ruelas DS, Suzuki B, Lim KC, Hopkins SD, McKerrow JH, Caffrey CR. RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening. PLoS Negl Trop Dis. 2010 Oct 19; 4(10):e850. PMID: 20976050; PMCID: PMC2957409.
  17. Kalkunte S, Boij R, Norris W, Friedman J, Lai Z, Kurtis J, Lim KH, Padbury JF, Matthiesen L, Sharma S. Sera from preeclampsia patients elicit symptoms of human disease in mice and provide a basis for an in vitro predictive assay. Am J Pathol. 2010 Nov; 177(5):2387-98. PMID: 20889559; PMCID: PMC2966797.
  18. Young B, Levine RJ, Salahuddin S, Qian C, Lim KH, Karumanchi SA, Rana S. The use of angiogenic biomarkers to differentiate non-HELLP related thrombocytopenia from HELLP syndrome. J Matern Fetal Neonatal Med. 2010 May; 23(5):366-70. PMID: 19701867; PMCID: PMC3132879.
  19. Steinberg G, Lee C, Rauh-Hain JA, Ecker J, Khankin EV, Hsu CD, Cohen B, Rana S, Karumanchi SA, Thadhani R, Hacker MR, Lim KH. Early-pregnancy soluble Fas levels in idiopathic small-for-gestational-age pregnancies. Am J Obstet Gynecol. 2010 Mar; 202(3):299.e1-7. PMID: 20207247.
    View in: PubMed
  20. Young B, Takoudes T, Lim KH, Rana S. Rupture of the posterior cul-de-sac during spontaneous labor. Obstet Gynecol. 2010 Feb; 115(2 Pt 2):414-7. PMID: 20093863.
    View in: PubMed
  21. Abdulla MH, Ruelas DS, Wolff B, Snedecor J, Lim KC, Xu F, Renslo AR, Williams J, McKerrow JH, Caffrey CR. Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening. PLoS Negl Trop Dis. 2009 Jul 14; 3(7):e478. PMID: 19597541; PMCID: PMC2702839.
  22. Lim KH, Salahuddin S, Qiu L, Fang H, Vitkin E, Ghiran IC, Modell MD, Takoudes T, Itzkan I, Hanlon EB, Sachs BP, Perelman LT. Light-scattering spectroscopy differentiates fetal from adult nucleated red blood cells: may lead to noninvasive prenatal diagnosis. Opt Lett. 2009 May 01; 34(9):1483-5. PMID: 19412313.
    View in: PubMed
  23. Bdolah Y, Lam C, Rajakumar A, Shivalingappa V, Mutter W, Sachs BP, Lim KH, Bdolah-Abram T, Epstein FH, Karumanchi SA. Twin pregnancy and the risk of preeclampsia: bigger placenta or relative ischemia? Am J Obstet Gynecol. 2008 Apr; 198(4):428.e1-6. PMID: 18191808.
    View in: PubMed
  24. Itzkan I, Qiu L, Fang H, Zaman MM, Vitkin E, Ghiran IC, Salahuddin S, Modell M, Andersson C, Kimerer LM, Cipolloni PB, Lim KH, Freedman SD, Bigio I, Sachs BP, Hanlon EB, Perelman LT. Confocal light absorption and scattering spectroscopic microscopy monitors organelles in live cells with no exogenous labels. Proc Natl Acad Sci U S A. 2007 Oct 30; 104(44):17255-60. PMID: 17956980; PMCID: PMC2077242.
  25. Salahuddin S, Lee Y, Vadnais M, Sachs BP, Karumanchi SA, Lim KH. Diagnostic utility of soluble fms-like tyrosine kinase 1 and soluble endoglin in hypertensive diseases of pregnancy. Am J Obstet Gynecol. 2007 Jul; 197(1):28.e1-6. PMID: 17618745.
    View in: PubMed
  26. Cohen A, Lim KH, Lee Y, Rana S, Karumanchi SA, Brown F. Circulating levels of the antiangiogenic marker soluble FMS-like tyrosine kinase 1 are elevated in women with pregestational diabetes and preeclampsia: angiogenic markers in preeclampsia and preexisting diabetes. Diabetes Care. 2007 Feb; 30(2):375-7. PMID: 17259514.
    View in: PubMed
  27. Abdulla MH, Lim KC, Sajid M, McKerrow JH, Caffrey CR. Schistosomiasis mansoni: novel chemotherapy using a cysteine protease inhibitor. PLoS Med. 2007 Jan; 4(1):e14. PMID: 17214506; PMCID: PMC1764436.
  28. Venkatesha S, Toporsian M, Lam C, Hanai J, Mammoto T, Kim YM, Bdolah Y, Lim KH, Yuan HT, Libermann TA, Stillman IE, Roberts D, D'Amore PA, Epstein FH, Sellke FW, Romero R, Sukhatme VP, Letarte M, Karumanchi SA. Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med. 2006 Jun; 12(6):642-9. PMID: 16751767.
    View in: PubMed
  29. Kazan-Tannus JF, Levine D, McKenzie C, Lim KH, Cohen B, Farrar N, Busse RF, Mulliken JB. Real-time magnetic resonance imaging aids prenatal diagnosis of isolated cleft palate. J Ultrasound Med. 2005 Nov; 24(11):1533-40. PMID: 16239657.
    View in: PubMed
  30. Lam C, Lim KH, Karumanchi SA. Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia. Hypertension. 2005 Nov; 46(5):1077-85. PMID: 16230516.
    View in: PubMed
  31. Levine RJ, Thadhani R, Qian C, Lam C, Lim KH, Yu KF, Blink AL, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA. Urinary placental growth factor and risk of preeclampsia. JAMA. 2005 Jan 05; 293(1):77-85. PMID: 15632339.
    View in: PubMed
  32. Lam C, Lim KH, Kang DH, Karumanchi SA. Uric acid and preeclampsia. Semin Nephrol. 2005 Jan; 25(1):56-60. PMID: 15660336.
    View in: PubMed
  33. Chiang G, Levine D, Hess P, Lim KH. Massive fetal ascites causing increased middle cerebral artery systolic velocity. Obstet Gynecol. 2004 Nov; 104(5 Pt 2):1136-40. PMID: 15516427.
    View in: PubMed
  34. Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med. 2004 Feb 12; 350(7):672-83. PMID: 14764923.
    View in: PubMed
  35. Hamar BD, Levine D, Katz NL, Lim KH. Expectant management of uterine dehiscence in the second trimester of pregnancy. Obstet Gynecol. 2003 Nov; 102(5 Pt 2):1139-42. PMID: 14607034.
    View in: PubMed
  36. Maynard SE, Min JY, Merchan J, Lim KH, Li J, Mondal S, Libermann TA, Morgan JP, Sellke FW, Stillman IE, Epstein FH, Sukhatme VP, Karumanchi SA. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest. 2003 Mar; 111(5):649-58. PMID: 12618519; PMCID: PMC151901.
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