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Jack Elias, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mo Y, Kim Y, Bang JY, Jung J, Lee CG, Elias JA, Kang HR. Mesenchymal Stem Cells Attenuate Asthmatic Inflammation and Airway Remodeling by Modulating Macrophages/Monocytes in the IL-13-Overexpressing Mouse Model. Immune Netw. 2022 Oct; 22(5):e40. PMID: 36381962; PMCID: PMC9634145.
    Citations:    
  2. Lee JH, Lee CM, Lee JH, Kim MO, Park JW, Kamle S, Akosman B, Herzog EL, Peng XY, Elias JA, Lee CG. Kasugamycin Is a Novel Chitinase 1 Inhibitor with Strong Antifibrotic Effects on Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2022 09; 67(3):309-319. PMID: 35679109; PMCID: PMC9447144.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  3. Kamle S, Ma B, Lee CM, Schor G, Zhou Y, Lee CG, Elias JA. Host chitinase 3-like-1 is a universal therapeutic target for SARS-CoV-2 viral variants in COVID-19. Elife. 2022 06 23; 11. PMID: 35735790; PMCID: PMC9273216.
    Citations:    Fields:    Translation:HumansCells
  4. Kim RL, Bang JY, Kim J, Mo Y, Kim Y, Lee CG, Elias JA, Kim HY, Kang HR. Mesenchymal stem cells exert their anti-asthmatic effects through macrophage modulation in a murine chronic asthma model. Sci Rep. 2022 06 13; 12(1):9811. PMID: 35697721; PMCID: PMC9192777.
    Citations: 1     Fields:    Translation:AnimalsCells
  5. Balnis J, Drake LA, Singer DV, Vincent CE, Korponay TC, D'Armiento J, Lee CG, Elias JA, Singer HA, Jaitovich A. Deaccelerated Myogenesis and Autophagy in Genetically Induced Pulmonary Emphysema. Am J Respir Cell Mol Biol. 2022 06; 66(6):623-637. PMID: 35286819; PMCID: PMC9163640.
    Citations: 2     Fields:    Translation:HumansAnimals
  6. Kim MN, Hong JY, Kim EG, Lee JW, Lee SY, Kim KW, Shim HS, Lee CG, Elias JA, Lee YJ, Sohn MH. A Novel Regulatory Role of Activated Leukocyte Cell-Adhesion Molecule in the Pathogenesis of Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2022 04; 66(4):415-427. PMID: 35073245.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  7. Lee SY, Lee CM, Ma B, Kamle S, Elias JA, Zhou Y, Lee CG. Targeting Chitinase 1 and Chitinase 3-Like 1 as Novel Therapeutic Strategy of Pulmonary Fibrosis. Front Pharmacol. 2022; 13:826471. PMID: 35370755; PMCID: PMC8969576.
    Citations:    
  8. Vasunilashorn SM, Dillon ST, Chan NY, Fong TG, Joseph M, Tripp B, Xie Z, Ngo LH, Lee CG, Elias JA, Otu HH, Inouye SK, Marcantonio ER, Libermann TA. Proteome-Wide Analysis Using SOMAscan Identifies and Validates Chitinase-3-Like Protein 1 as a Risk and Disease Marker of Delirium Among Older Adults Undergoing Major Elective Surgery. J Gerontol A Biol Sci Med Sci. 2022 03 03; 77(3):484-493. PMID: 35239952; PMCID: PMC8893174.
    Citations: 2     Fields:    Translation:Humans
  9. Connolly K, Lehoux M, O'Rourke R, Assetta B, Erdemir GA, Elias JA, Lee CG, Huang YA. Potential role of chitinase-3-like protein 1 (CHI3L1/YKL-40) in neurodegeneration and Alzheimer's disease. Alzheimers Dement. 2022 Mar 02. PMID: 35234337; PMCID: PMC9437141.
    Citations: 3     Fields:    
  10. Kamle S, Ma B, Lee CM, Schor G, Zhou Y, Lee CG, Elias JA. Host Chitinase 3-like-1 is a Universal Therapeutic Target for SARS-CoV-2 Viral Variants in COVID 19. bioRxiv. 2022 Feb 26. PMID: 35118470; PMCID: PMC8811903.
    Citations:    
  11. Kamle S, Ma B, He CH, Akosman B, Zhou Y, Lee CM, El-Deiry WS, Huntington K, Liang O, Machan JT, Kang MJ, Shin HJ, Mizoguchi E, Lee CG, Elias JA. Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19. JCI Insight. 2021 11 08; 6(21). PMID: 34747367; PMCID: PMC8663553.
    Citations: 9     Fields:    Translation:HumansCells
  12. Ma B, Akosman B, Kamle S, Lee CM, He CH, Koo JS, Lee CG, Elias JA. CHI3L1 regulates PD-L1 and anti-CHI3L1-PD-1 antibody elicits synergistic antitumor responses. J Clin Invest. 2021 11 01; 131(21). PMID: 34720089; PMCID: PMC8553560.
    Citations: 4     Fields:    Translation:Animals
  13. Balnis J, Drake LA, Vincent CE, Korponay TC, Singer DV, Lacomis D, Lee CG, Elias JA, Jourd'heuil D, Singer HA, Jaitovich A. SDH Subunit C Regulates Muscle Oxygen Consumption and Fatigability in an Animal Model of Pulmonary Emphysema. Am J Respir Cell Mol Biol. 2021 09; 65(3):259-271. PMID: 33909984; PMCID: PMC8485989.
    Citations: 5     Fields:    Translation:Animals
  14. Shan Z, Li L, Atkins CL, Wang M, Wen Y, Jeong J, Moreno NF, Feng D, Gui X, Zhang N, Lee CG, Elias JA, Lee WM, Gao B, Lam FW, An Z, Ju C. Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment. Elife. 2021 06 10; 10. PMID: 34110284; PMCID: PMC8233036.
    Citations: 4     Fields:    Translation:AnimalsCells
  15. Park SY, Hong JY, Lee SY, Lee SH, Kim MJ, Kim SY, Kim KW, Shim HS, Park MS, Lee CG, Elias JA, Sohn MH, Yoon HG. Club cell-specific role of programmed cell death 5 in pulmonary fibrosis. Nat Commun. 2021 05 19; 12(1):2923. PMID: 34011956; PMCID: PMC8134485.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  16. Schmitz NA, Thakare RP, Chung CS, Lee CM, Elias JA, Lee CG, LeBlanc BW. Chitotriosidase Activity Is Counterproductive in a Mouse Model of Systemic Candidiasis. Front Immunol. 2021; 12:626798. PMID: 33796101; PMCID: PMC8007879.
    Citations: 1     Fields:    Translation:AnimalsCells
  17. Kamle S, Ma B, He CH, Akosman B, Zhou Y, Lee CM, El-Deiry WS, Huntington K, Liang O, Machan JT, Kang MJ, Shin HJ, Mizoguchi E, Lee CG, Elias JA. Chitinase 3-like-1 is a Therapeutic Target That Mediates the Effects of Aging in COVID-19. bioRxiv. 2021 Feb 16. PMID: 33442679; PMCID: PMC7805436.
    Citations:    
  18. Zhang S, Sousa A, Lin M, Iwano A, Jain R, Ma B, Lee CM, Park JW, Kamle S, Carlson R, Lee GG, Elias JA, Wands JR. Role of Chitinase 3-Like 1 Protein in the Pathogenesis of Hepatic Insulin Resistance in Nonalcoholic Fatty Liver Disease. Cells. 2021 01 20; 10(2). PMID: 33498326; PMCID: PMC7909438.
    Citations: 3     Fields:    Translation:AnimalsCells
  19. Huntington KE, Louie AD, Lee CG, Elias JA, Ross EA, El-Deiry WS. Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients infected with SARS-CoV-2. Elife. 2021 01 14; 10. PMID: 33443016; PMCID: PMC7872512.
    Citations: 8     Fields:    Translation:Humans
  20. Lananna BV, McKee CA, King MW, Del-Aguila JL, Dimitry JM, Farias FHG, Nadarajah CJ, Xiong DD, Guo C, Cammack AJ, Elias JA, Zhang J, Cruchaga C, Musiek ES. Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis. Sci Transl Med. 2020 12 16; 12(574). PMID: 33328329; PMCID: PMC7808313.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  21. Huntington KE, Louie AD, Lee CG, Elias JA, Ross EA, El-Deiry WS. Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients with COVID-19. medRxiv. 2020 Nov 27. PMID: 33269361; PMCID: PMC7709181.
    Citations:    
  22. Kim EG, Kim MN, Hong JY, Lee JW, Kim SY, Kim KW, Lee CG, Elias JA, Song TW, Sohn MH. Chitinase 3-Like 1 Contributes to Food Allergy via M2 Macrophage Polarization. Allergy Asthma Immunol Res. 2020 Nov; 12(6):1012-1028. PMID: 32935492; PMCID: PMC7492506.
    Citations: 9     
  23. Balnis J, Lee CG, Elias JA, Jaitovich A. Hypercapnia-Driven Skeletal Muscle Dysfunction in an Animal Model of Pulmonary Emphysema Suggests a Complex Phenotype. Front Physiol. 2020; 11:600290. PMID: 33192616; PMCID: PMC7658396.
    Citations: 4     
  24. Zhou L, Huntington K, Zhang S, Carlsen L, So EY, Parker C, Sahin I, Safran H, Kamle S, Lee CM, Lee CG, Elias JA, Campbell KS, Naik MT, Atwood WJ, Youssef E, Pachter JA, Navaraj A, Seyhan AA, Liang O, El-Deiry WS. Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells. bioRxiv. 2020 Sep 02. PMID: 32793908; PMCID: PMC7418728.
    Citations: 1     
  25. He CH, Lee CG, Ma B, Kamle S, Choi AMK, Elias JA. N-Glycosylation Regulates Chitinase 3-like-1 and IL-13 Ligand Binding to IL-13 Receptor a2. Am J Respir Cell Mol Biol. 2020 09; 63(3):386-395. PMID: 32402213; PMCID: PMC7462338.
    Citations: 7     Fields:    Translation:AnimalsCells
  26. Balnis J, Vincent CE, Jones AJ, Drake LA, Coon JJ, Lee CG, Elias JA, Singer HA, Jaitovich A. Established Biomarkers of Chronic Obstructive Pulmonary Disease Reflect Skeletal Muscle Integrity's Response to Exercise in an Animal Model of Pulmonary Emphysema. Am J Respir Cell Mol Biol. 2020 08; 63(2):266-269. PMID: 32735164; PMCID: PMC7397768.
    Citations: 6     Fields:    Translation:Animals
  27. Balnis J, Korponay TC, Vincent CE, Singer DV, Adam AP, Lacomis D, Lee CG, Elias JA, Singer HA, Jaitovich A. IL-13-driven pulmonary emphysema leads to skeletal muscle dysfunction attenuated by endurance exercise. J Appl Physiol (1985). 2020 01 01; 128(1):134-148. PMID: 31774358; PMCID: PMC7054638.
    Citations: 10     Fields:    Translation:Animals
  28. Ko J, Mills T, Huang J, Chen NY, Mertens TCJ, Collum SD, Lee G, Xiang Y, Han L, Zhou Y, Lee CG, Elias JA, Jyothula SSK, Rajagopal K, Karmouty-Quintana H, Blackburn MR. Transforming growth factor ß1 alters the 3'-UTR of mRNA to promote lung fibrosis. J Biol Chem. 2019 10 25; 294(43):15781-15794. PMID: 31488543; PMCID: PMC6816088.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  29. Kwak EJ, Hong JY, Kim MN, Kim SY, Kim SH, Park CO, Kim KW, Lee CG, Elias JA, Jee HM, Sohn MH. Chitinase 3-like 1 drives allergic skin inflammation via Th2 immunity and M2 macrophage activation. Clin Exp Allergy. 2019 11; 49(11):1464-1474. PMID: 31397016.
    Citations: 14     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  30. Lee CM, He CH, Park JW, Lee JH, Kamle S, Ma B, Akosman B, Cotez R, Chen E, Zhou Y, Herzog EL, Ryu C, Peng X, Rosas IO, Poli S, Bostwick CF, Choi AM, Elias JA, Lee CG. Chitinase 1 regulates pulmonary fibrosis by modulating TGF-ß/SMAD7 pathway via TGFBRAP1 and FOXO3. Life Sci Alliance. 2019 06; 2(3). PMID: 31085559; PMCID: PMC6516052.
    Citations: 9     Fields:    Translation:HumansCells
  31. Kim MJ, Shim DH, Cha HR, Moon KY, Yang CM, Hwang SJ, Kim KW, Park JH, Lee CG, Elias JA, Sohn MH, Lee JM. Chitinase 3-like 1 protein plays a critical role in respiratory syncytial virus-induced airway inflammation. Allergy. 2019 04; 74(4):685-697. PMID: 30402955; PMCID: PMC7159489.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  32. Ryter SW, Rosas IO, Owen CA, Martinez FJ, Choi ME, Lee CG, Elias JA, Choi AMK. Mitochondrial Dysfunction as a Pathogenic Mediator of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis. Ann Am Thorac Soc. 2018 12; 15(Suppl 4):S266-S272. PMID: 30759019; PMCID: PMC6944396.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  33. Lee CM, Cho SJ, Cho WK, Park JW, Lee JH, Choi AM, Rosas IO, Zheng M, Peltz G, Lee CG, Elias JA. Laminin a1 is a genetic modifier of TGF-ß1-stimulated pulmonary fibrosis. JCI Insight. 2018 09 20; 3(18). PMID: 30232270.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  34. Sharma L, Amick AK, Vasudevan S, Lee SW, Marion CR, Liu W, Brady V, Losier A, Bermejo SD, Britto CJ, Lee CG, Elias JA, Dela Cruz CS. Regulation and Role of Chitotriosidase during Lung Infection with Klebsiella pneumoniae. J Immunol. 2018 07 15; 201(2):615-626. PMID: 29891554; PMCID: PMC6291403.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  35. Breyne K, Steenbrugge J, Demeyere K, Lee CG, Elias JA, Petzl W, Smith DGE, Germon P, Meyer E. Immunomodulation of Host Chitinase 3-Like 1 During a Mammary Pathogenic Escherichia coli Infection. Front Immunol. 2018; 9:1143. PMID: 29892291.
    Citations: 4     Fields:    Translation:AnimalsCells
  36. Kim DH, Park HJ, Lim S, Koo JH, Lee HG, Choi JO, Oh JH, Ha SJ, Kang MJ, Lee CM, Lee CG, Elias JA, Choi JM. Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis. Nat Commun. 2018 02 05; 9(1):503. PMID: 29403003.
    Citations: 33     Fields:    Translation:AnimalsCells
  37. Zhou Y, He CH, Yang DS, Nguyen T, Cao Y, Kamle S, Lee CM, Gochuico BR, Gahl WA, Shea BS, Lee CG, Elias JA. Galectin-3 Interacts with the CHI3L1 Axis and Contributes to Hermansky-Pudlak Syndrome Lung Disease. J Immunol. 2018 03 15; 200(6):2140-2153. PMID: 29427412; PMCID: PMC5839999.
    Citations: 19     Fields:    Translation:AnimalsCells
  38. Korde A, Jin L, Zhang JG, Ramaswamy A, Hu B, Kolahian S, Guardela BJ, Herazo-Maya J, Siegfried JM, Stabile L, Pisani MA, Herbst RS, Kaminski N, Elias JA, Puchalski JT, Takyar SS. Lung Endothelial MicroRNA-1 Regulates Tumor Growth and Angiogenesis. Am J Respir Crit Care Med. 2017 12 01; 196(11):1443-1455. PMID: 28853613; PMCID: PMC5736970.
    Citations: 13     Fields:    Translation:AnimalsCells
  39. Murray LA, Habiel DM, Hohmann M, Camelo A, Shang H, Zhou Y, Coelho AL, Peng X, Gulati M, Crestani B, Sleeman MA, Mustelin T, Moore MW, Ryu C, Osafo-Addo AD, Elias JA, Lee CG, Hu B, Herazo-Maya JD, Knight DA, Hogaboam CM, Herzog EL. Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis. JCI Insight. 2017 Aug 17; 2(16). PMID: 28814671; PMCID: PMC5621899.
    Citations: 24     Fields:    
  40. Montgomery TA, Xu L, Mason S, Chinnadurai A, Lee CG, Elias JA, Cantley LG. Breast Regression Protein-39/Chitinase 3-Like 1 Promotes Renal Fibrosis after Kidney Injury via Activation of Myofibroblasts. J Am Soc Nephrol. 2017 Nov; 28(11):3218-3226. PMID: 28679671; PMCID: PMC5661290.
    Citations: 19     Fields:    Translation:AnimalsCells
  41. Thomas BJ, Kan-O K, Loveland KL, Elias JA, Bardin PG. In the Shadow of Fibrosis: Innate Immune Suppression Mediated by Transforming Growth Factor-ß. Am J Respir Cell Mol Biol. 2016 12; 55(6):759-766. PMID: 27603223.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  42. Lee CM, He CH, Nour AM, Zhou Y, Ma B, Park JW, Kim KH, Cruz CD, Sharma L, Nasr ML, Modis Y, Lee CG, Elias JA. Corrigendum: IL-13Ra2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses. Nat Commun. 2016 11 14; 7:13541. PMID: 27841275.
    Citations: 1     Fields:    
  43. Lee CM, He CH, Nour AM, Zhou Y, Ma B, Park JW, Kim KH, Dela Cruz C, Sharma L, Nasr ML, Modis Y, Lee CG, Elias JA. IL-13Ra2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses. Nat Commun. 2016 09 15; 7:12752. PMID: 27629921.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  44. Peng X, Moore M, Mathur A, Zhou Y, Sun H, Gan Y, Herazo-Maya JD, Kaminski N, Hu X, Pan H, Ryu C, Osafo-Addo A, Homer RJ, Feghali-Bostwick C, Fares WH, Gulati M, Hu B, Lee CG, Elias JA, Herzog EL. Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis. FASEB J. 2016 12; 30(12):4056-4070. PMID: 27609773; PMCID: PMC5102121.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  45. Golestani R, Razavian M, Ye Y, Zhang J, Jung JJ, Toczek J, Gona K, Kim HY, Elias JA, Lee CG, Homer RJ, Sadeghi MM. Matrix Metalloproteinase-Targeted Imaging of Lung Inflammation and Remodeling. J Nucl Med. 2017 Jan; 58(1):138-143. PMID: 27469361; PMCID: PMC5209638.
    Citations: 13     Fields:    Translation:Animals
  46. Puthumana J, Hall IE, Reese PP, Schröppel B, Weng FL, Thiessen-Philbrook H, Doshi MD, Rao V, Lee CG, Elias JA, Cantley LG, Parikh CR. YKL-40 Associates with Renal Recovery in Deceased Donor Kidney Transplantation. J Am Soc Nephrol. 2017 02; 28(2):661-670. PMID: 27451287; PMCID: PMC5280016.
    Citations: 27     Fields:    Translation:Humans
  47. Marion CR, Wang J, Sharma L, Losier A, Lui W, Andrews N, Elias JA, Kazmierczak BI, Roy CR, Dela Cruz CS. Chitinase 3-Like 1 (Chil1) Regulates Survival and Macrophage-Mediated Interleukin-1ß and Tumor Necrosis Factor Alpha during Pseudomonas aeruginosa Pneumonia. Infect Immun. 2016 07; 84(7):2094-2104. PMID: 27141083; PMCID: PMC4936356.
    Citations: 12     Fields:    Translation:AnimalsCells
  48. Ma B, Herzog EL, Moore M, Lee CM, Na SH, Lee CG, Elias JA. RIG-like Helicase Regulation of Chitinase 3-like 1 Axis and Pulmonary Metastasis. Sci Rep. 2016 05 20; 6:26299. PMID: 27198666; PMCID: PMC4873814.
    Citations: 11     Fields:    Translation:AnimalsCells
  49. Nezgovorova V, Liu Q, Hu B, Villalobos JL, Yan X, Niu N, Holm C, Grant NP, Marone S, Ravage-Mass L, Lee CG, Elias JA, Cohn L, Chupp GL. Sputum Gene Expression of IL-13 Receptor a2 Chain Correlates with Airflow Obstruction and Helper T-Cell Type 2 Inflammation in Asthma. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S96-7. PMID: 27027964; PMCID: PMC5015742.
    Citations: 3     Fields:    
  50. Cusanovich DA, Caliskan M, Billstrand C, Michelini K, Chavarria C, De Leon S, Mitrano A, Lewellyn N, Elias JA, Chupp GL, Lang RM, Shah SJ, Decara JM, Gilad Y, Ober C. Integrated analyses of gene expression and genetic association studies in a founder population. Hum Mol Genet. 2016 05 15; 25(10):2104-2112. PMID: 26931462; PMCID: PMC5062579.
    Citations: 10     Fields:    Translation:Humans
  51. Yoon PO, Park JW, Lee CM, Kim SH, Kim HN, Ko Y, Bae SJ, Yun S, Park JH, Kwon T, Kim WS, Lee J, Lu Q, Kang HR, Cho WK, Elias JA, Yang JS, Park HO, Lee K, Lee CG. Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis. J Biol Chem. 2016 Mar 18; 291(12):6433-46. PMID: 26817844; PMCID: PMC4813554.
    Citations: 16     Fields:    Translation:AnimalsCells
  52. Wang J, Liu W, Marion C, Singh R, Andrews N, Lee CG, Elias JA, Dela Cruz CS. Regulation of Retinoic Acid Receptor Beta by Interleukin-15 in the Lung during Cigarette Smoking and Influenza Virus Infection. Am J Respir Cell Mol Biol. 2015 Dec; 53(6):822-33. PMID: 25923039; PMCID: PMC4742936.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  53. Kang MJ, Yoon CM, Nam M, Kim DH, Choi JM, Lee CG, Elias JA. Role of Chitinase 3-Like-1 in Interleukin-18-Induced Pulmonary Type 1, Type 2, and Type 17 Inflammation; Alveolar Destruction; and Airway Fibrosis in the Murine Lung. Am J Respir Cell Mol Biol. 2015 Dec; 53(6):863-71. PMID: 25955511; PMCID: PMC4742933.
    Citations: 25     Fields:    Translation:AnimalsCells
  54. Low D, Subramaniam R, Lin L, Aomatsu T, Mizoguchi A, Ng A, DeGruttola AK, Lee CG, Elias JA, Andoh A, Mino-Kenudson M, Mizoguchi E. Chitinase 3-like 1 induces survival and proliferation of intestinal epithelial cells during chronic inflammation and colitis-associated cancer by regulating S100A9. Oncotarget. 2015 Nov 03; 6(34):36535-50. PMID: 26431492.
    Citations: 34     Fields:    Translation:HumansAnimals
  55. Zhou Y, He CH, Herzog EL, Peng X, Lee CM, Nguyen TH, Gulati M, Gochuico BR, Gahl WA, Slade ML, Lee CG, Elias JA. Chitinase 3-like-1 and its receptors in Hermansky-Pudlak syndrome-associated lung disease. J Clin Invest. 2015 Aug 03; 125(8):3178-92. PMID: 26121745; PMCID: PMC4563747.
    Citations: 35     Fields:    Translation:HumansAnimalsCTClinical Trials
  56. Kang MJ, Yoon CM, Kim BH, Lee CM, Zhou Y, Sauler M, Homer R, Dhamija A, Boffa D, West AP, Shadel GS, Ting JP, Tedrow JR, Kaminski N, Kim WJ, Lee CG, Oh YM, Elias JA. Suppression of NLRX1 in chronic obstructive pulmonary disease. J Clin Invest. 2015 Jun; 125(6):2458-62. PMID: 25938787; PMCID: PMC4497738.
    Citations: 38     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  57. Ahangari F, Sood A, Ma B, Takyar S, Schuyler M, Qualls C, Dela Cruz CS, Chupp GL, Lee CG, Elias JA. Chitinase 3-like-1 regulates both visceral fat accumulation and asthma-like Th2 inflammation. Am J Respir Crit Care Med. 2015 Apr 01; 191(7):746-57. PMID: 25629580; PMCID: PMC4407482.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  58. Patel AS, Song JW, Chu SG, Mizumura K, Osorio JC, Shi Y, El-Chemaly S, Lee CG, Rosas IO, Elias JA, Choi AM, Morse D. Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis. PLoS One. 2015; 10(3):e0121246. PMID: 25785991.
    Citations: 77     Fields:    Translation:HumansAnimalsCells
  59. Wiesner DL, Specht CA, Lee CK, Smith KD, Mukaremera L, Lee ST, Lee CG, Elias JA, Nielsen JN, Boulware DR, Bohjanen PR, Jenkins MK, Levitz SM, Nielsen K. Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection. PLoS Pathog. 2015 Mar; 11(3):e1004701. PMID: 25764512; PMCID: PMC4357429.
    Citations: 90     Fields:    Translation:AnimalsCells
  60. Ma B, Herzog EL, Lee CG, Peng X, Lee CM, Chen X, Rockwell S, Koo JS, Kluger H, Herbst RS, Sznol M, Elias JA. Role of chitinase 3-like-1 and semaphorin 7a in pulmonary melanoma metastasis. Cancer Res. 2015 Feb 01; 75(3):487-96. PMID: 25511377; PMCID: PMC4321965.
    Citations: 40     Fields:    Translation:AnimalsCells
  61. Hall IE, Stern EP, Cantley LG, Elias JA, Parikh CR. Urine YKL-40 is associated with progressive acute kidney injury or death in hospitalized patients. BMC Nephrol. 2014 Aug 15; 15:133. PMID: 25128003; PMCID: PMC4144686.
    Citations: 20     Fields:    Translation:Humans
  62. Erdman LK, Petes C, Lu Z, Dhabangi A, Musoke C, Cserti-Gazdewich CM, Lee CG, Liles WC, Elias JA, Kain KC. Chitinase 3-like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case-control study of African children. Malar J. 2014 Jul 21; 13:279. PMID: 25047113; PMCID: PMC4114103.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  63. Ridker PM, Chasman DI, Rose L, Loscalzo J, Elias JA. Plasma levels of the proinflammatory chitin-binding glycoprotein YKL-40, variation in the chitinase 3-like 1 gene (CHI3L1), and incident cardiovascular events. J Am Heart Assoc. 2014 Jun 23; 3(3):e000897. PMID: 24958781.
    Citations: 17     Fields:    Translation:Humans
  64. Zhou Y, Peng H, Sun H, Peng X, Tang C, Gan Y, Chen X, Mathur A, Hu B, Slade MD, Montgomery RR, Shaw AC, Homer RJ, White ES, Lee CM, Moore MW, Gulati M, Lee CG, Elias JA, Herzog EL. Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis. Sci Transl Med. 2014 Jun 11; 6(240):240ra76. PMID: 24920662; PMCID: PMC4340473.
    Citations: 90     Fields:    Translation:HumansAnimalsCells
  65. Jafari B, Elias JA, Mohsenin V. Increased plasma YKL-40/chitinase-3-like-protein-1 is associated with endothelial dysfunction in obstructive sleep apnea. PLoS One. 2014; 9(5):e98629. PMID: 24878721; PMCID: PMC4039537.
    Citations: 6     Fields:    Translation:Humans
  66. Tran HT, Lee IA, Low D, Kamba A, Mizoguchi A, Shi HN, Lee CG, Elias JA, Mizoguchi E. Chitinase 3-like 1 synergistically activates IL6-mediated STAT3 phosphorylation in intestinal epithelial cells in murine models of infectious colitis. Inflamm Bowel Dis. 2014 May; 20(5):835-46. PMID: 24694795.
    Citations: 13     Fields:    Translation:AnimalsCells
  67. Lee CM, Park JW, Cho WK, Zhou Y, Han B, Yoon PO, Chae J, Elias JA, Lee CG. Modifiers of TGF-ß1 effector function as novel therapeutic targets of pulmonary fibrosis. Korean J Intern Med. 2014 May; 29(3):281-90. PMID: 24851060; PMCID: PMC4028515.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  68. Mannam P, Shinn AS, Srivastava A, Neamu RF, Walker WE, Bohanon M, Merkel J, Kang MJ, Dela Cruz CS, Ahasic AM, Pisani MA, Trentalange M, West AP, Shadel GS, Elias JA, Lee PJ. MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2014 Apr 01; 306(7):L604-19. PMID: 24487387; PMCID: PMC3962628.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  69. Takyar S, Vasavada H, Zhang JG, Ahangari F, Niu N, Liu Q, Lee CG, Cohn L, Elias JA. VEGF controls lung Th2 inflammation via the miR-1-Mpl (myeloproliferative leukemia virus oncogene)-P-selectin axis. J Exp Med. 2013 Sep 23; 210(10):1993-2010. PMID: 24043765; PMCID: PMC3782056.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  70. He CH, Lee CG, Dela Cruz CS, Lee CM, Zhou Y, Ahangari F, Ma B, Herzog EL, Rosenberg SA, Li Y, Nour AM, Parikh CR, Schmidt I, Modis Y, Cantley L, Elias JA. Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor a2. Cell Rep. 2013 Aug 29; 4(4):830-41. PMID: 23972995.
    Citations: 118     Fields:    Translation:HumansAnimalsCells
  71. Zhou Y, Kang MJ, Jha BK, Silverman RH, Lee CG, Elias JA. Role of ribonuclease L in viral pathogen-associated molecular pattern/influenza virus and cigarette smoke-induced inflammation and remodeling. J Immunol. 2013 Sep 01; 191(5):2637-46. PMID: 23913960; PMCID: PMC3750064.
    Citations: 10     Fields:    Translation:AnimalsCellsPHPublic Health
  72. Ghelfi E, Yu CW, Elmasri H, Terwelp M, Lee CG, Bhandari V, Comhair SA, Erzurum SC, Hotamisligil GS, Elias JA, Cataltepe S. Fatty acid binding protein 4 regulates VEGF-induced airway angiogenesis and inflammation in a transgenic mouse model: implications for asthma. Am J Pathol. 2013 Apr; 182(4):1425-33. PMID: 23391391; PMCID: PMC3620401.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  73. Schmidt IM, Hall IE, Kale S, Lee S, He CH, Lee Y, Chupp GL, Moeckel GW, Lee CG, Elias JA, Parikh CR, Cantley LG. Chitinase-like protein Brp-39/YKL-40 modulates the renal response to ischemic injury and predicts delayed allograft function. J Am Soc Nephrol. 2013 Feb; 24(2):309-19. PMID: 23291472.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  74. Reilkoff RA, Peng H, Murray LA, Peng X, Russell T, Montgomery R, Feghali-Bostwick C, Shaw A, Homer RJ, Gulati M, Mathur A, Elias JA, Herzog EL. Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-ß1-induced pulmonary fibrosis. Am J Respir Crit Care Med. 2013 Jan 15; 187(2):180-8. PMID: 23220917; PMCID: PMC3570653.
    Citations: 55     Fields:    Translation:HumansAnimalsCells
  75. Cho WK, Lee CM, Kang MJ, Huang Y, Giordano FJ, Lee PJ, Trow TK, Homer RJ, Sessa WC, Elias JA, Lee CG. IL-13 receptor a2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2013 Jan 15; 304(2):L112-24. PMID: 23125252; PMCID: PMC3543640.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  76. Zhou Y, Lee JY, Lee CM, Cho WK, Kang MJ, Koff JL, Yoon PO, Chae J, Park HO, Elias JA, Lee CG. Amphiregulin, an epidermal growth factor receptor ligand, plays an essential role in the pathogenesis of transforming growth factor-ß-induced pulmonary fibrosis. J Biol Chem. 2012 Dec 07; 287(50):41991-2000. PMID: 23086930; PMCID: PMC3516745.
    Citations: 58     Fields:    Translation:AnimalsCells
  77. Lee CG, Herzog EL, Ahangari F, Zhou Y, Gulati M, Lee CM, Peng X, Feghali-Bostwick C, Jimenez SA, Varga J, Elias JA. Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-ß1 signaling. J Immunol. 2012 Sep 01; 189(5):2635-44. PMID: 22826322; PMCID: PMC4336775.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  78. Dela Cruz CS, Liu W, He CH, Jacoby A, Gornitzky A, Ma B, Flavell R, Lee CG, Elias JA. Chitinase 3-like-1 promotes Streptococcus pneumoniae killing and augments host tolerance to lung antibacterial responses. Cell Host Microbe. 2012 Jul 19; 12(1):34-46. PMID: 22817986; PMCID: PMC3613130.
    Citations: 71     Fields:    Translation:AnimalsCells
  79. Lee CG, Dela Cruz CS, Ma B, Ahangari F, Zhou Y, Halaban R, Sznol M, Elias JA. Chitinase-like proteins in lung injury, repair, and metastasis. Proc Am Thorac Soc. 2012 May; 9(2):57-61. PMID: 22550243; PMCID: PMC3359113.
    Citations: 11     Fields:    Translation:HumansAnimals
  80. Lee CG, Dela Cruz CS, Herzog E, Rosenberg SM, Ahangari F, Elias JA. YKL-40, a chitinase-like protein at the intersection of inflammation and remodeling. Am J Respir Crit Care Med. 2012 Apr 01; 185(7):692-4. PMID: 22467800.
    Citations: 16     Fields:    Translation:Humans
  81. Kang MJ, Choi JM, Kim BH, Lee CM, Cho WK, Choe G, Kim DH, Lee CG, Elias JA. IL-18 induces emphysema and airway and vascular remodeling via IFN-?, IL-17A, and IL-13. Am J Respir Crit Care Med. 2012 Jun 01; 185(11):1205-17. PMID: 22383501; PMCID: PMC3373071.
    Citations: 52     Fields:    Translation:Animals
  82. Kearns MT, Dalal S, Horstmann SA, Richens TR, Tanaka T, Doe JM, Boe DM, Voelkel NF, Taraseviciene-Stewart L, Janssen WJ, Lee CG, Elias JA, Bratton D, Tuder RM, Henson PM, Vandivier RW. Vascular endothelial growth factor enhances macrophage clearance of apoptotic cells. Am J Physiol Lung Cell Mol Physiol. 2012 Apr 01; 302(7):L711-8. PMID: 22307908; PMCID: PMC3330764.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  83. Bhandari V, Choo-Wing R, Harijith A, Sun H, Syed MA, Homer RJ, Elias JA. Increased hyperoxia-induced lung injury in nitric oxide synthase 2 null mice is mediated via angiopoietin 2. Am J Respir Cell Mol Biol. 2012 May; 46(5):668-76. PMID: 22227562; PMCID: PMC3359903.
    Citations: 25     Fields:    Translation:Animals
  84. Lee CG, Ma B, Takyar S, Ahangari F, Delacruz C, He CH, Elias JA. Studies of vascular endothelial growth factor in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2011 Nov; 8(6):512-5. PMID: 22052929; PMCID: PMC3359071.
    Citations: 32     Fields:    Translation:HumansAnimals
  85. Homer RJ, Elias JA, Lee CG, Herzog E. Modern concepts on the role of inflammation in pulmonary fibrosis. Arch Pathol Lab Med. 2011 Jun; 135(6):780-8. PMID: 21631273.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  86. Peng X, Mathai SK, Murray LA, Russell T, Reilkoff R, Chen Q, Gulati M, Elias JA, Bucala R, Gan Y, Herzog EL. Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor ß1-induced lung fibrosis. Fibrogenesis Tissue Repair. 2011 May 17; 4(1):12. PMID: 21586112; PMCID: PMC3123188.
    Citations: 23     
  87. Lee BJ, Moon HG, Shin TS, Jeon SG, Lee EY, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK. Protective effects of basic fibroblast growth factor in the development of emphysema induced by interferon-?. Exp Mol Med. 2011 Apr 30; 43(4):169-78. PMID: 21297377; PMCID: PMC3085735.
    Citations: 15     Fields:    Translation:Animals
  88. Elias JA, Lee CG. IL-13 in asthma. The successful integration of lessons from mice and humans. Am J Respir Crit Care Med. 2011 Apr 15; 183(8):957-8. PMID: 21498814.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  89. Ma B, Dela Cruz CS, Hartl D, Kang MJ, Takyar S, Homer RJ, Lee CG, Elias JA. RIG-like helicase innate immunity inhibits vascular endothelial growth factor tissue responses via a type I IFN-dependent mechanism. Am J Respir Crit Care Med. 2011 May 15; 183(10):1322-35. PMID: 21278304; PMCID: PMC3114061.
    Citations: 9     Fields:    Translation:Animals
  90. Lee CG, Da Silva CA, Dela Cruz CS, Ahangari F, Ma B, Kang MJ, He CH, Takyar S, Elias JA. Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury. Annu Rev Physiol. 2011; 73:479-501. PMID: 21054166; PMCID: PMC3864643.
    Citations: 330     Fields:    Translation:HumansAnimals
  91. Murray LA, Chen Q, Kramer MS, Hesson DP, Argentieri RL, Peng X, Gulati M, Homer RJ, Russell T, van Rooijen N, Elias JA, Hogaboam CM, Herzog EL. TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P. Int J Biochem Cell Biol. 2011 Jan; 43(1):154-62. PMID: 21044893.
    Citations: 166     Fields:    Translation:HumansAnimalsCells
  92. Wright PL, Yu J, Di YP, Homer RJ, Chupp G, Elias JA, Cohn L, Sessa WC. Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation. J Exp Med. 2010 Nov 22; 207(12):2595-607. PMID: 20975041; PMCID: PMC2989775.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  93. Kim YS, Choi SJ, Choi JP, Jeon SG, Oh S-, Lee BJ, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK. IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model. Exp Mol Med. 2010 Aug 31; 42(8):533-46. PMID: 20592486.
    Citations: 9     Fields:    Translation:AnimalsCells
  94. Matsuura H, Hartl D, Kang MJ, Dela Cruz CS, Koller B, Chupp GL, Homer RJ, Zhou Y, Cho WK, Elias JA, Lee CG. Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema. Am J Respir Cell Mol Biol. 2011 Jun; 44(6):777-86. PMID: 20656949; PMCID: PMC3135840.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  95. Da Silva CA, Pochard P, Lee CG, Elias JA. Chitin particles are multifaceted immune adjuvants. Am J Respir Crit Care Med. 2010 Dec 15; 182(12):1482-91. PMID: 20656945; PMCID: PMC3029935.
    Citations: 29     Fields:    Translation:AnimalsCells
  96. Sohn MH, Kang MJ, Matsuura H, Bhandari V, Chen NY, Lee CG, Elias JA. The chitinase-like proteins breast regression protein-39 and YKL-40 regulate hyperoxia-induced acute lung injury. Am J Respir Crit Care Med. 2010 Oct 01; 182(7):918-28. PMID: 20558631; PMCID: PMC2970863.
    Citations: 55     Fields:    Translation:HumansAnimalsCells
  97. Lee CG, Elias JA. Role of breast regression protein-39/YKL-40 in asthma and allergic responses. Allergy Asthma Immunol Res. 2010 Jan; 2(1):20-7. PMID: 20224674; PMCID: PMC2831605.
    Citations: 39     
  98. Hong EG, Ko HJ, Cho YR, Kim HJ, Ma Z, Yu TY, Friedline RH, Kurt-Jones E, Finberg R, Fischer MA, Granger EL, Norbury CC, Hauschka SD, Philbrick WM, Lee CG, Elias JA, Kim JK. Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle. Diabetes. 2009 Nov; 58(11):2525-35. PMID: 19690064; PMCID: PMC2768157.
    Citations: 170     Fields:    Translation:AnimalsCells
  99. Chapoval SP, Lee CG, Tang C, Keegan AD, Cohn L, Bottomly K, Elias JA. Lung vascular endothelial growth factor expression induces local myeloid dendritic cell activation. Clin Immunol. 2009 Sep; 132(3):371-84. PMID: 19553159; PMCID: PMC2780370.
    Citations: 17     Fields:    Translation:AnimalsCells
  100. Lee CG, Hartl D, Lee GR, Koller B, Matsuura H, Da Silva CA, Sohn MH, Cohn L, Homer RJ, Kozhich AA, Humbles A, Kearley J, Coyle A, Chupp G, Reed J, Flavell RA, Elias JA. Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med. 2009 May 11; 206(5):1149-66. PMID: 19414556; PMCID: PMC2715037.
    Citations: 195     Fields:    Translation:HumansAnimalsCells
  101. Hartl D, He CH, Koller B, Da Silva CA, Kobayashi Y, Lee CG, Flavell RA, Elias JA. Acidic mammalian chitinase regulates epithelial cell apoptosis via a chitinolytic-independent mechanism. J Immunol. 2009 Apr 15; 182(8):5098-106. PMID: 19342690; PMCID: PMC2666938.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  102. Siner JM, Bhandari V, Engle KM, Elias JA, Siegel MD. Elevated serum angiopoietin 2 levels are associated with increased mortality in sepsis. Shock. 2009 Apr; 31(4):348-53. PMID: 18791490.
    Citations: 56     Fields:    Translation:Humans
  103. Da Silva CA, Chalouni C, Williams A, Hartl D, Lee CG, Elias JA. Chitin is a size-dependent regulator of macrophage TNF and IL-10 production. J Immunol. 2009 Mar 15; 182(6):3573-82. PMID: 19265136.
    Citations: 107     Fields:    Translation:AnimalsCells
  104. Hartl D, Lee CG, Da Silva CA, Chupp GL, Elias JA. Novel biomarkers in asthma: chemokines and chitinase-like proteins. Curr Opin Allergy Clin Immunol. 2009 Feb; 9(1):60-6. PMID: 19532094.
    Citations: 26     Fields:    Translation:Humans
  105. Sohn MH, Lee JH, Kim KW, Kim SW, Lee SH, Kim KE, Kim KH, Lee CG, Elias JA, Lee MG. Genetic variation in the promoter region of chitinase 3-like 1 is associated with atopy. Am J Respir Crit Care Med. 2009 Mar 15; 179(6):449-56. PMID: 19106306.
    Citations: 31     Fields:    Translation:HumansCells
  106. Lee CG, Da Silva CA, Lee JY, Hartl D, Elias JA. Chitin regulation of immune responses: an old molecule with new roles. Curr Opin Immunol. 2008 Dec; 20(6):684-9. PMID: 18938241; PMCID: PMC2605627.
    Citations: 103     Fields:    Translation:HumansAnimalsCells
  107. Hartl D, He CH, Koller B, Da Silva CA, Homer R, Lee CG, Elias JA. Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells. J Biol Chem. 2008 Nov 28; 283(48):33472-82. PMID: 18824549; PMCID: PMC2586247.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  108. Da Silva CA, Hartl D, Liu W, Lee CG, Elias JA. TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. J Immunol. 2008 Sep 15; 181(6):4279-86. PMID: 18768886; PMCID: PMC2577310.
    Citations: 104     Fields:    Translation:AnimalsCells
  109. Kang MJ, Lee CG, Lee JY, Dela Cruz CS, Chen ZJ, Enelow R, Elias JA. Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice. J Clin Invest. 2008 Aug; 118(8):2771-84. PMID: 18654661; PMCID: PMC2483678.
    Citations: 119     Fields:    Translation:AnimalsCellsPHPublic Health
  110. Lee CG, Hartl D, Matsuura H, Dunlop FM, Scotney PD, Fabri LJ, Nash AD, Chen NY, Tang CY, Chen Q, Homer RJ, Baca M, Elias JA. Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production. Am J Respir Cell Mol Biol. 2008 Dec; 39(6):739-46. PMID: 18617680; PMCID: PMC2586049.
    Citations: 19     Fields:    Translation:AnimalsCellsPHPublic Health
  111. Bhandari V, Choo-Wing R, Lee CG, Yusuf K, Nedrelow JH, Ambalavanan N, Malkus H, Homer RJ, Elias JA. Developmental regulation of NO-mediated VEGF-induced effects in the lung. Am J Respir Cell Mol Biol. 2008 Oct; 39(4):420-30. PMID: 18441284; PMCID: PMC2551703.
    Citations: 35     Fields:    Translation:HumansAnimals
  112. Pulichino AM, Wang IM, Caron A, Mortimer J, Auger A, Boie Y, Elias JA, Kartono A, Xu L, Menetski J, Sayegh CE. Identification of transforming growth factor beta1-driven genetic programs of acute lung fibrosis. Am J Respir Cell Mol Biol. 2008 Sep; 39(3):324-36. PMID: 18403781.
    Citations: 25     Fields:    Translation:HumansAnimals
  113. Ober C, Tan Z, Sun Y, Possick JD, Pan L, Nicolae R, Radford S, Parry RR, Heinzmann A, Deichmann KA, Lester LA, Gern JE, Lemanske RF, Nicolae DL, Elias JA, Chupp GL. Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. N Engl J Med. 2008 Apr 17; 358(16):1682-91. PMID: 18403759; PMCID: PMC2629486.
    Citations: 224     Fields:    Translation:Humans
  114. Chupp GL, Lee CG, Jarjour N, Shim YM, Holm CT, He S, Dziura JD, Reed J, Coyle AJ, Kiener P, Cullen M, Grandsaigne M, Dombret MC, Aubier M, Pretolani M, Elias JA. A chitinase-like protein in the lung and circulation of patients with severe asthma. N Engl J Med. 2007 Nov 15; 357(20):2016-27. PMID: 18003958.
    Citations: 219     Fields:    Translation:Humans
  115. Chapoval SP, Al-Garawi A, Lora JM, Strickland I, Ma B, Lee PJ, Homer RJ, Ghosh S, Coyle AJ, Elias JA. Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13. J Immunol. 2007 Nov 15; 179(10):7030-41. PMID: 17982094.
    Citations: 23     Fields:    Translation:AnimalsCells
  116. Yamasaki M, Kang HR, Homer RJ, Chapoval SP, Cho SJ, Lee BJ, Elias JA, Lee CG. P21 regulates TGF-beta1-induced pulmonary responses via a TNF-alpha-signaling pathway. Am J Respir Cell Mol Biol. 2008 Mar; 38(3):346-53. PMID: 17932374; PMCID: PMC2258454.
    Citations: 16     Fields:    Translation:AnimalsCells
  117. Kang HR, Lee CG, Homer RJ, Elias JA. Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis. J Exp Med. 2007 May 14; 204(5):1083-93. PMID: 17485510; PMCID: PMC2118575.
    Citations: 86     Fields:    Translation:Animals
  118. Bhandari V, Elias JA. The role of angiopoietin 2 in hyperoxia-induced acute lung injury. Cell Cycle. 2007 May 02; 6(9):1049-52. PMID: 17438375.
    Citations: 13     Fields:    Translation:HumansAnimals
  119. Bhandari V, Choo-Wing R, Homer RJ, Elias JA. Increased hyperoxia-induced mortality and acute lung injury in IL-13 null mice. J Immunol. 2007 Apr 15; 178(8):4993-5000. PMID: 17404281.
    Citations: 21     Fields:    Translation:Animals
  120. Choo-Wing R, Nedrelow JH, Homer RJ, Elias JA, Bhandari V. Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2007 Jul; 293(1):L142-50. PMID: 17400600.
    Citations: 40     Fields:    Translation:HumansAnimals
  121. Jeon SG, Lee CG, Oh MH, Chun EY, Gho YS, Cho SH, Kim JH, Min KU, Kim YY, Kim YK, Elias JA. Recombinant basic fibroblast growth factor inhibits the airway hyperresponsiveness, mucus production, and lung inflammation induced by an allergen challenge. J Allergy Clin Immunol. 2007 Apr; 119(4):831-7. PMID: 17289133.
    Citations: 22     Fields:    Translation:Animals
  122. Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, Rochester C, Cain H, Chupp G, Yoon HJ, Elias JA. IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation. J Immunol. 2007 Feb 01; 178(3):1948-59. PMID: 17237446.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  123. Siner JM, Jiang G, Cohen ZI, Shan P, Zhang X, Lee CG, Elias JA, Lee PJ. VEGF-induced heme oxygenase-1 confers cytoprotection from lethal hyperoxia in vivo. FASEB J. 2007 May; 21(7):1422-32. PMID: 17264168.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  124. Kang HR, Cho SJ, Lee CG, Homer RJ, Elias JA. Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12. J Biol Chem. 2007 Mar 09; 282(10):7723-32. PMID: 17209037.
    Citations: 80     Fields:    Translation:Animals
  125. Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, Lee PJ, Geick A, de Fougerolles AR, Elias JA. Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. Nat Med. 2006 Nov; 12(11):1286-93. PMID: 17086189; PMCID: PMC2768268.
    Citations: 158     Fields:    Translation:Animals
  126. Zhou W, Hashimoto K, Moore ML, Elias JA, Zhu Z, Durbin J, Colasurdo G, Rutigliano JA, Chiappetta CL, Goleniewska K, O'Neal JF, Graham BS, Peebles RS. IL-13 is associated with reduced illness and replication in primary respiratory syncytial virus infection in the mouse. Microbes Infect. 2006 Nov-Dec; 8(14-15):2880-9. PMID: 17110149; PMCID: PMC1811125.
    Citations: 12     Fields:    Translation:AnimalsCells
  127. Ingram JL, Antao-Menezes A, Mangum JB, Lyght O, Lee PJ, Elias JA, Bonner JC. Opposing actions of Stat1 and Stat6 on IL-13-induced up-regulation of early growth response-1 and platelet-derived growth factor ligands in pulmonary fibroblasts. J Immunol. 2006 Sep 15; 177(6):4141-8. PMID: 16951379.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  128. Shim YM, Zhu Z, Zheng T, Lee CG, Homer RJ, Ma B, Elias JA. Role of 5-lipoxygenase in IL-13-induced pulmonary inflammation and remodeling. J Immunol. 2006 Aug 01; 177(3):1918-24. PMID: 16849505.
    Citations: 13     Fields:    Translation:AnimalsCells
  129. Lee CG, Cho S, Homer RJ, Elias JA. Genetic control of transforming growth factor-beta1-induced emphysema and fibrosis in the murine lung. Proc Am Thorac Soc. 2006 Aug; 3(6):476-477. PMID: 16921114.
    Citations: 18     Fields:    Translation:Animals
  130. Kang MJ, Lee CG, Cho SJ, Homer RJ, Elias JA. IFN-gamma-dependent DNA injury and/or apoptosis are critical in cigarette smoke-induced murine emphysema. Proc Am Thorac Soc. 2006 Aug; 3(6):517-8. PMID: 16921135.
    Citations: 5     Fields:    Translation:Animals
  131. Elias JA, Kang MJ, Crothers K, Crouthers K, Homer R, Lee CG. State of the art. Mechanistic heterogeneity in chronic obstructive pulmonary disease: insights from transgenic mice. Proc Am Thorac Soc. 2006 Aug; 3(6):494-8. PMID: 16921126.
    Citations: 32     Fields:    Translation:AnimalsCells
  132. Bhandari V, Choo-Wing R, Chapoval SP, Lee CG, Tang C, Kim YK, Ma B, Baluk P, Lin MI, McDonald DM, Homer RJ, Sessa WC, Elias JA. Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung. Proc Natl Acad Sci U S A. 2006 Jul 18; 103(29):11021-6. PMID: 16832062; PMCID: PMC1544167.
    Citations: 49     Fields:    Translation:AnimalsCells
  133. Lee CG, Kang HR, Homer RJ, Chupp G, Elias JA. Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling. Proc Am Thorac Soc. 2006 Jul; 3(5):418-23. PMID: 16799085; PMCID: PMC2658706.
    Citations: 47     Fields:    Translation:HumansAnimals
  134. Ma B, Blackburn MR, Lee CG, Homer RJ, Liu W, Flavell RA, Boyden L, Lifton RP, Sun CX, Young HW, Elias JA. Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis. J Clin Invest. 2006 May; 116(5):1274-83. PMID: 16670768; PMCID: PMC1451205.
    Citations: 34     Fields:    Translation:Animals
  135. Ma B, Liu W, Homer RJ, Lee PJ, Coyle AJ, Lora JM, Lee CG, Elias JA. Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol. 2006 Apr 15; 176(8):4968-78. PMID: 16585593.
    Citations: 13     Fields:    Translation:AnimalsCells
  136. Homer RJ, Zhu Z, Cohn L, Lee CG, White WI, Chen S, Elias JA. Differential expression of chitinases identify subsets of murine airway epithelial cells in allergic inflammation. Am J Physiol Lung Cell Mol Physiol. 2006 Sep; 291(3):L502-11. PMID: 16556727.
    Citations: 41     Fields:    Translation:Animals
  137. Bhandari V, Elias JA. Cytokines in tolerance to hyperoxia-induced injury in the developing and adult lung. Free Radic Biol Med. 2006 Jul 01; 41(1):4-18. PMID: 16781448.
    Citations: 66     Fields:    Translation:Humans
  138. Cho SJ, Kang MJ, Homer RJ, Kang HR, Zhang X, Lee PJ, Elias JA, Lee CG. Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling. J Biol Chem. 2006 Mar 24; 281(12):8161-8. PMID: 16439363.
    Citations: 43     Fields:    Translation:AnimalsCells
  139. Lee PJ, Zhang X, Shan P, Ma B, Lee CG, Homer RJ, Zhu Z, Rincon M, Mossman BT, Elias JA. ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo. J Clin Invest. 2006 Jan; 116(1):163-73. PMID: 16374521; PMCID: PMC1319220.
    Citations: 51     Fields:    Translation:Animals
  140. Ma B, Kang MJ, Lee CG, Chapoval S, Liu W, Chen Q, Coyle AJ, Lora JM, Picarella D, Homer RJ, Elias JA. Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema. J Clin Invest. 2005 Dec; 115(12):3460-72. PMID: 16284650; PMCID: PMC1280966.
    Citations: 39     Fields:    Translation:AnimalsCells
  141. Chunn JL, Mohsenin A, Young HW, Lee CG, Elias JA, Kellems RE, Blackburn MR. Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations. Am J Physiol Lung Cell Mol Physiol. 2006 Mar; 290(3):L579-87. PMID: 16258000.
    Citations: 47     Fields:    Translation:AnimalsCells
  142. Elias JA, Homer RJ, Hamid Q, Lee CG. Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma. J Allergy Clin Immunol. 2005 Sep; 116(3):497-500. PMID: 16159614.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  143. Zheng T, Kang MJ, Crothers K, Zhu Z, Liu W, Lee CG, Rabach LA, Chapman HA, Homer RJ, Aldous D, De Sanctis GT, Desanctis G, Underwood S, Graupe M, Flavell RA, Schmidt JA, Elias JA. Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema. J Immunol. 2005 Jun 15; 174(12):8106-15. PMID: 15944319.
    Citations: 64     Fields:    Translation:HumansAnimalsCells
  144. Becker PM, Waltenberger J, Yachechko R, Mirzapoiazova T, Sham JS, Lee CG, Elias JA, Verin AD. Neuropilin-1 regulates vascular endothelial growth factor-mediated endothelial permeability. Circ Res. 2005 Jun 24; 96(12):1257-65. PMID: 15920019.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  145. Peng T, Hao L, Madri JA, Su X, Elias JA, Stahl GL, Squinto S, Wang Y. Role of C5 in the development of airway inflammation, airway hyperresponsiveness, and ongoing airway response. J Clin Invest. 2005 Jun; 115(6):1590-600. PMID: 15902311; PMCID: PMC1090470.
    Citations: 25     Fields:    Translation:HumansAnimals
  146. Elias JA, Lee CG. Lipid let loose in pulmonary emphysema. Nat Med. 2005 May; 11(5):471-2. PMID: 15875047.
    Citations: 4     Fields:    Translation:Humans
  147. He CH, Waxman AB, Lee CG, Link H, Rabach ME, Ma B, Chen Q, Zhu Z, Zhong M, Nakayama K, Nakayama KI, Homer R, Elias JA. Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury. J Clin Invest. 2005 Apr; 115(4):1039-48. PMID: 15841185; PMCID: PMC1070412.
    Citations: 44     Fields:    Translation:AnimalsCells
  148. Chen Q, Rabach L, Noble P, Zheng T, Lee CG, Homer RJ, Elias JA. IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol. 2005 Feb 15; 174(4):2305-13. PMID: 15699166.
    Citations: 21     Fields:    Translation:AnimalsCells
  149. Homer RJ, Elias JA. Airway remodeling in asthma: therapeutic implications of mechanisms. Physiology (Bethesda). 2005 Feb; 20:28-35. PMID: 15653837.
    Citations: 51     Fields:    Translation:HumansAnimals
  150. Baluk P, Lee CG, Link H, Ator E, Haskell A, Elias JA, McDonald DM. Regulated angiogenesis and vascular regression in mice overexpressing vascular endothelial growth factor in airways. Am J Pathol. 2004 Oct; 165(4):1071-85. PMID: 15466375; PMCID: PMC1618646.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  151. Lee CG, Link H, Baluk P, Homer RJ, Chapoval S, Bhandari V, Kang MJ, Cohn L, Kim YK, McDonald DM, Elias JA. Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nat Med. 2004 Oct; 10(10):1095-103. PMID: 15378055; PMCID: PMC3434232.
    Citations: 200     Fields:    Translation:HumansAnimalsCells
  152. Vicencio AG, Lee CG, Cho SJ, Eickelberg O, Chuu Y, Haddad GG, Elias JA. Conditional overexpression of bioactive transforming growth factor-beta1 in neonatal mouse lung: a new model for bronchopulmonary dysplasia? Am J Respir Cell Mol Biol. 2004 Dec; 31(6):650-6. PMID: 15333328.
    Citations: 73     Fields:    Translation:HumansAnimals
  153. Lee CG, Cho SJ, Kang MJ, Chapoval SP, Lee PJ, Noble PW, Yehualaeshet T, Lu B, Flavell RA, Milbrandt J, Homer RJ, Elias JA. Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis. J Exp Med. 2004 Aug 02; 200(3):377-89. PMID: 15289506; PMCID: PMC2211975.
    Citations: 168     Fields:    Translation:Animals
  154. Zhu Z, Zheng T, Homer RJ, Kim YK, Chen NY, Cohn L, Hamid Q, Elias JA. Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science. 2004 Jun 11; 304(5677):1678-82. PMID: 15192232.
    Citations: 299     Fields:    Translation:HumansAnimalsCells
  155. Hjoberg J, Shore S, Kobzik L, Okinaga S, Hallock A, Vallone J, Subramaniam V, De Sanctis GT, Elias JA, Drazen JM, Silverman ES. Expression of nitric oxide synthase-2 in the lungs decreases airway resistance and responsiveness. J Appl Physiol (1985). 2004 Jul; 97(1):249-59. PMID: 15020581.
    Citations: 11     Fields:    Translation:Animals
  156. Ma B, Zhu Z, Homer RJ, Gerard C, Strieter R, Elias JA. The C10/CCL6 chemokine and CCR1 play critical roles in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol. 2004 Feb 01; 172(3):1872-81. PMID: 14734772.
    Citations: 39     Fields:    Translation:AnimalsCells
  157. Cohn L, Elias JA, Chupp GL. Asthma: mechanisms of disease persistence and progression. Annu Rev Immunol. 2004; 22:789-815. PMID: 15032597.
    Citations: 267     Fields:    Translation:HumansAnimalsCells
  158. Blackburn MR, Lee CG, Young HW, Zhu Z, Chunn JL, Kang MJ, Banerjee SK, Elias JA. Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. J Clin Invest. 2003 Aug; 112(3):332-44. PMID: 12897202; PMCID: PMC166289.
    Citations: 77     Fields:    Translation:AnimalsCells
  159. Wang J, Chen Q, Corne J, Zhu Z, Lee CG, Bhandari V, Homer RJ, Elias JA. Pulmonary expression of leukemia inhibitory factor induces B cell hyperplasia and confers protection in hyperoxia. J Biol Chem. 2003 Aug 15; 278(33):31226-32. PMID: 12782633.
    Citations: 17     Fields:    Translation:AnimalsCells
  160. Tuder RM, Petrache I, Elias JA, Voelkel NF, Henson PM. Apoptosis and emphysema: the missing link. Am J Respir Cell Mol Biol. 2003 May; 28(5):551-4. PMID: 12707010.
    Citations: 79     Fields:    Translation:HumansAnimals
  161. Waxman AB, Mahboubi K, Knickelbein RG, Mantell LL, Manzo N, Pober JS, Elias JA. Interleukin-11 and interleukin-6 protect cultured human endothelial cells from H2O2-induced cell death. Am J Respir Cell Mol Biol. 2003 Oct; 29(4):513-22. PMID: 12730073.
    Citations: 34     Fields:    Translation:HumansCells
  162. Elias JA, Lee CG, Zheng T, Shim Y, Zhu Z. Interleukin-13 and leukotrienes: an intersection of pathogenetic schema. Am J Respir Cell Mol Biol. 2003 Apr; 28(4):401-4. PMID: 12654627.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  163. Zheng T, Zhu Z, Liu W, Lee CG, Chen Q, Homer RJ, Elias JA. Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro. J Allergy Clin Immunol. 2003 Apr; 111(4):720-8. PMID: 12704349.
    Citations: 26     Fields:    Translation:Animals
  164. Elias JA, Zheng T, Lee CG, Homer RJ, Chen Q, Ma B, Blackburn M, Zhu Z. Transgenic modeling of interleukin-13 in the lung. Chest. 2003 Mar; 123(3 Suppl):339S-45S. PMID: 12628967.
    Citations: 14     Fields:    Translation:Animals
  165. Zhu Z, Enhorning G, Zheng T, Chen Q, Chen NY, Homer R, Elias JA. Interleukin-13 induces surfactant function abnormality in the murine lung. Chest. 2003 Mar; 123(3 Suppl):375S-6S. PMID: 12628990.
    Citations: 1     Fields:    Translation:Animals
  166. Elias JA, Lee CG, Zheng T, Ma B, Homer RJ, Zhu Z. New insights into the pathogenesis of asthma. J Clin Invest. 2003 Feb; 111(3):291-7. PMID: 12569150; PMCID: PMC151878.
    Citations: 127     Fields:    Translation:HumansAnimalsCells
  167. Belperio JA, Dy M, Burdick MD, Xue YY, Li K, Elias JA, Keane MP. Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2002 Oct; 27(4):419-27. PMID: 12356575.
    Citations: 85     Fields:    Translation:AnimalsCells
  168. Lanone S, Zheng T, Zhu Z, Liu W, Lee CG, Ma B, Chen Q, Homer RJ, Wang J, Rabach LA, Rabach ME, Shipley JM, Shapiro SD, Senior RM, Elias JA. Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling. J Clin Invest. 2002 Aug; 110(4):463-74. PMID: 12189240; PMCID: PMC150413.
    Citations: 111     Fields:    Translation:Animals
  169. Lee CG, Homer RJ, Cohn L, Link H, Jung S, Craft JE, Graham BS, Johnson TR, Elias JA. Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways. J Biol Chem. 2002 Sep 20; 277(38):35466-74. PMID: 12107190.
    Citations: 50     Fields:    Translation:AnimalsCells
  170. Homer RJ, Zheng T, Chupp G, He S, Zhu Z, Chen Q, Ma B, Hite RD, Gobran LI, Rooney SA, Elias JA. Pulmonary type II cell hypertrophy and pulmonary lipoproteinosis are features of chronic IL-13 exposure. Am J Physiol Lung Cell Mol Physiol. 2002 Jul; 283(1):L52-9. PMID: 12060560.
    Citations: 16     Fields:    Translation:Animals
  171. Kuperman DA, Huang X, Koth LL, Chang GH, Dolganov GM, Zhu Z, Elias JA, Sheppard D, Erle DJ. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med. 2002 Aug; 8(8):885-9. PMID: 12091879.
    Citations: 327     Fields:    Translation:HumansAnimalsCells
  172. Zhu Z, Zheng T, Lee CG, Homer RJ, Elias JA. Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling. Semin Cell Dev Biol. 2002 Apr; 13(2):121-8. PMID: 12127145.
    Citations: 65     Fields:    Translation:AnimalsCells
  173. Zhu Z, Ma B, Zheng T, Homer RJ, Lee CG, Charo IF, Noble P, Elias JA. IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol. 2002 Mar 15; 168(6):2953-62. PMID: 11884467.
    Citations: 57     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.