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Albert Arthur Hyman, M.D.

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  1. Badejo AM, Hodnette C, Dhaliwal JS, Casey DB, Pankey E, Murthy SN, Nossaman BD, Hyman AL, Kadowitz PJ. Mitochondrial aldehyde dehydrogenase mediates vasodilator responses of glyceryl trinitrate and sodium nitrite in the pulmonary vascular bed of the rat. Am J Physiol Heart Circ Physiol. 2010 Sep; 299(3):H819-26. PMID: 20543077; PMCID: PMC2944483.
    View in: PubMed, PubMed Central
  2. Casey DB, Badejo AM, Dhaliwal JS, Sikora JL, Fokin A, Golwala NH, Greco AJ, Murthy SN, Nossaman BD, Hyman AL, Kadowitz PJ. Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat. Am J Physiol Heart Circ Physiol. 2010 Jul; 299(1):H184-92. PMID: 20435851; PMCID: PMC2904133.
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  3. Casey DB, Badejo AM, Dhaliwal JS, Murthy SN, Hyman AL, Nossaman BD, Kadowitz PJ. Pulmonary vasodilator responses to sodium nitrite are mediated by an allopurinol-sensitive mechanism in the rat. Am J Physiol Heart Circ Physiol. 2009 Feb; 296(2):H524-33. PMID: 19074675; PMCID: PMC2643888.
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  4. Dhaliwal JS, Casey DB, Greco AJ, Badejo AM, Gallen TB, Murthy SN, Nossaman BD, Hyman AL, Kadowitz PJ. Rho kinase and Ca2+ entry mediate increased pulmonary and systemic vascular resistance in L-NAME-treated rats. Am J Physiol Lung Cell Mol Physiol. 2007 Nov; 293(5):L1306-13. PMID: 17766587.
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  5. Nossaman BD, Baber SR, Nazim MM, Waldron PR, Hyman AL, Kadowitz PJ. Acetaminophen, phenacetin and dipyrone do not modulate pressor responses to arachidonic Acid or to pressor agents. Pharmacology. 2007; 80(4):249-60. PMID: 17627114.
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  6. Baber SR, Deng W, Master RG, Bunnell BA, Taylor BK, Murthy SN, Hyman AL, Kadowitz PJ. Intratracheal mesenchymal stem cell administration attenuates monocrotaline-induced pulmonary hypertension and endothelial dysfunction. Am J Physiol Heart Circ Physiol. 2007 Feb; 292(2):H1120-8. PMID: 16980338.
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  7. Bunnell BA, Deng W, Robinson CM, Waldron PR, Bivalacqua TJ, Baber SR, Hyman AL, Kadowitz PJ. Potential application for mesenchymal stem cells in the treatment of cardiovascular diseases. Can J Physiol Pharmacol. 2005 Jul; 83(7):529-39. PMID: 16091779.
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  8. Baber SR, Deng W, Rodriguez J, Master RG, Bivalacqua TJ, Hyman AL, Kadowitz PJ. Vasoactive prostanoids are generated from arachidonic acid by COX-1 and COX-2 in the mouse. Am J Physiol Heart Circ Physiol. 2005 Oct; 289(4):H1476-87. PMID: 15863457.
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  9. Chattergoon NN, D'Souza FM, Deng W, Chen H, Hyman AL, Kadowitz PJ, Jeter JR. Antiproliferative effects of calcitonin gene-related peptide in aortic and pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2005 Jan; 288(1):L202-11. PMID: 15257984.
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  10. Nguyen TM, Quintal RE, Khuri BN, Yount RD, Shah A, Abourahma AH, Naddour F, Hyman AL, Glancy DL. Stenting of atherosclerotic stenoses in anomalously arising coronary arteries. J Invasive Cardiol. 2004 May; 16(5):283-6. PMID: 15152119.
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  11. Baber SR, Hyman AL, Kadowitz PJ. Role of COX-1 and -2 in prostanoid generation and modulation of angiotensin II responses. Am J Physiol Heart Circ Physiol. 2003 Dec; 285(6):H2399-410. PMID: 14613912.
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  12. Baber SR, Champion HC, Bivalacqua TJ, Hyman AL, Kadowitz PJ. Role of cyclooxygenase-2 in the generation of vasoactive prostanoids in the rat pulmonary and systemic vascular beds. Circulation. 2003 Aug 19; 108(7):896-901. PMID: 12900348.
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  13. Deng W, Bivalacqua TJ, Chattergoon NN, Hyman AL, Jeter JR, Kadowitz PJ. Adenoviral gene transfer of eNOS: high-level expression in ex vivo expanded marrow stromal cells. Am J Physiol Cell Physiol. 2003 Nov; 285(5):C1322-9. PMID: 12878489.
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  14. Champion HC, Bivalacqua TJ, Pierce RL, Murphy WA, Coy DH, Hyman AL, Kadowitz PJ. Responses to human CGRP, ADM, and PAMP in human thymic arteries. Am J Physiol Regul Integr Comp Physiol. 2003 Feb; 284(2):R531-7. PMID: 12529288.
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  15. Bivalacqua TJ, Hyman AL, Kadowitz PJ, Paolocci N, Kass DA, Champion HC. Role of calcitonin gene-related peptide (CGRP) in chronic hypoxia-induced pulmonary hypertension in the mouse. Influence of gene transfer in vivo. Regul Pept. 2002 Oct 15; 108(2-3):129-33. PMID: 12220736.
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  16. Champion HC, Bivalacqua TJ, Greenberg SS, Giles TD, Hyman AL, Kadowitz PJ. Adenoviral gene transfer of endothelial nitric-oxide synthase (eNOS) partially restores normal pulmonary arterial pressure in eNOS-deficient mice. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):13248-53. PMID: 12237402; PMCID: PMC130619.
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  17. Ortiz LA, Champion HC, Lasky JA, Gambelli F, Gozal E, Hoyle GW, Beasley MB, Hyman AL, Friedman M, Kadowitz PJ. Enalapril protects mice from pulmonary hypertension by inhibiting TNF-mediated activation of NF-kappaB and AP-1. Am J Physiol Lung Cell Mol Physiol. 2002 Jun; 282(6):L1209-21. PMID: 12003776.
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  18. Champion HC, Bivalacqua TJ, Zadina JE, Kastin AJ, Hyman AL, Kadowitz PJ. Role of nitric oxide in mediating vasodilator responses to opioid peptides in the rat. Clin Exp Pharmacol Physiol. 2002 Mar; 29(3):229-32. PMID: 11906489.
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  19. Hyman AL, De Witt BJ, Gumusel B, Hao Q, Kadowitz PJ, Lippton HL. L-NAME enhances responses to atrial natriuretic peptide in the pulmonary vascular bed of the cat. J Appl Physiol (1985). 2001 Jun; 90(6):2101-8. PMID: 11356772.
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  20. De Vos K, Severin F, Van Herreweghe F, Vancompernolle K, Goossens V, Hyman A, Grooten J. Tumor necrosis factor induces hyperphosphorylation of kinesin light chain and inhibits kinesin-mediated transport of mitochondria. J Cell Biol. 2000 Jun 12; 149(6):1207-14. PMID: 10851018; PMCID: PMC2175118.
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  21. Champion HC, Bivalacqua TJ, Toyoda K, Heistad DD, Hyman AL, Kadowitz PJ. In vivo gene transfer of prepro-calcitonin gene-related peptide to the lung attenuates chronic hypoxia-induced pulmonary hypertension in the mouse. Circulation. 2000 Feb 29; 101(8):923-30. PMID: 10694533.
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  22. Champion HC, Villnave DJ, Tower A, Kadowitz PJ, Hyman AL. A novel right-heart catheterization technique for in vivo measurement of vascular responses in lungs of intact mice. Am J Physiol Heart Circ Physiol. 2000 Jan; 278(1):H8-H15. PMID: 10644578.
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  23. Champion HC, Bivalacqua TJ, Hyman AL, Ignarro LJ, Hellstrom WJ, Kadowitz PJ. Gene transfer of endothelial nitric oxide synthase to the penis augments erectile responses in the aged rat. Proc Natl Acad Sci U S A. 1999 Sep 28; 96(20):11648-52. PMID: 10500231; PMCID: PMC18088.
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  24. Champion HC, Bivalacqua TJ, D'Souza FM, Ortiz LA, Jeter JR, Toyoda K, Heistad DD, Hyman AL, Kadowitz PJ. Gene transfer of endothelial nitric oxide synthase to the lung of the mouse in vivo. Effect on agonist-induced and flow-mediated vascular responses. Circ Res. 1999 Jun 25; 84(12):1422-32. PMID: 10381895.
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  25. Gumusel B, Hao Q, Hyman AL, Kadowitz PJ, Champion HC, Chang JK, Mehta JL, Lippton H. Analysis of responses to adrenomedullin-(13-52) in the pulmonary vascular bed of rats. Am J Physiol. 1998 Apr; 274(4 Pt 2):H1255-63. PMID: 9575929.
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  26. Hyman AL, Hao Q, Tower A, Kadowitz PJ, Champion HC, Gumusel B, Lippton H. Novel catheterization technique for the in vivo measurement of pulmonary vascular responses in rats. Am J Physiol. 1998 Apr; 274(4 Pt 2):H1218-29. PMID: 9575925.
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  27. Hao Q, Hyman AL, Choe EU, Flint LM, Ferrara JJ. A novel model to study the effects of burn lymph on pulmonary vascular hemodynamic variables. J Trauma. 1997 Sep; 43(3):453-7. PMID: 9314307.
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  28. Sabates BL, Pigott JD, Choe EU, Cruz MP, Lippton HL, Hyman AL, Flint LM, Ferrara JJ. Adrenomedullin mediates coronary vasodilation through adenosine receptors and KATP channels. J Surg Res. 1997 Feb 01; 67(2):163-8. PMID: 9073563.
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  29. Gumusel B, Hao Q, Hyman A, Chang JK, Kapusta DR, Lippton H. Nociceptin: an endogenous agonist for central opioid like1 (ORL1) receptors possesses systemic vasorelaxant properties. Life Sci. 1997; 60(8):PL141-5. PMID: 9042395.
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  30. Ferrara JJ, Hoang TV, Choe EU, Lippton HL, Hyman AL, Flint LM. Characterization of alpha-adrenoceptor activity in term-newborn piglet mesentery. J Pharm Pharmacol. 1996 Dec; 48(12):1298-301. PMID: 9004194.
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  31. Yang BC, Lippton H, Gumusel B, Hyman A, Mehta JL. Adrenomedullin dilates rat pulmonary artery rings during hypoxia: role of nitric oxide and vasodilator prostaglandins. J Cardiovasc Pharmacol. 1996 Sep; 28(3):458-62. PMID: 8877594.
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  32. Sabates B, Granger T, Choe E, Pigott J, Lippton H, Hyman A, Flint L, Ferrara J. Adrenomedullin is inactivated in the lungs of neonatal piglets. J Pharm Pharmacol. 1996 Jun; 48(6):578-80. PMID: 8832490.
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  33. Hoang TV, Choe EU, Lippton HL, Hyman AL, Flint LM, Ferrara JJ. Effect of maturation on alpha-adrenoceptor activity in newborn piglet mesentery. J Surg Res. 1996 Mar; 61(2):330-8. PMID: 8656604.
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  34. Gumusel B, Chang JK, Hao Q, Hyman A, Lippton H. Adrenotensin: an adrenomedullin gene product contracts pulmonary blood vessels. Peptides. 1996; 17(3):461-5. PMID: 8735973.
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  35. Lippton HL, Hao Q, Erdemli O, Hyman A. Role of G proteins in the vasodilator response to endothelin isopeptides in vivo. J Appl Physiol (1985). 1995 Jun; 78(6):2062-9. PMID: 7665400.
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  36. Heaton J, Lin B, Chang JK, Steinberg S, Hyman A, Lippton H. Pulmonary vasodilation to adrenomedullin: a novel peptide in humans. Am J Physiol. 1995 Jun; 268(6 Pt 2):H2211-5. PMID: 7611471.
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  37. Ferrara JJ, Franklin EW, Choe EU, Taheri PA, Westervelt CL, Lippton HL, Hyman AL, Flint LM. Serotonin receptors regulate canine regional vasodilator responses to burn. Crit Care Med. 1995 Jun; 23(6):1112-6. PMID: 7774224.
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  38. Lippton H, Choe E, Franklin E, Grivas T, Flint L, Hyman A, Ferrara J. Femoral vasodilation to cromakalim is blocked by U37883A, a non-sulphonylurea that selectively inhibits KATP channels. J Pharm Pharmacol. 1995 Mar; 47(3):243-5. PMID: 7602489.
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  39. Hall JM, Siney L, Lippton H, Hyman A, Kang-Chang J, Brain SD. Interaction of human adrenomedullin 13-52 with calcitonin gene-related peptide receptors in the microvasculature of the rat and hamster. Br J Pharmacol. 1995 Feb; 114(3):592-7. PMID: 7735685; PMCID: PMC1510020.
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  40. Ferrara JJ, Franklin EW, Choe EU, Lippton HL, Hyman AL, Flint LM. Effects of methysergide administration on edema formation at the site of scald. J Appl Physiol (1985). 1995 Jan; 78(1):191-7. PMID: 7713811.
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  41. Taheri P, Choe E, Lippton H, Hyman A, Flint L, Ferrara J. Autonomic control of the regional hemodynamic response to scald. Life Sci. 1995; 56(9):701-7. PMID: 7869852.
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  42. Gumusel B, Chang JK, Hyman A, Lippton H. Adrenotensin: an ADM gene product with the opposite effects of ADM. Life Sci. 1995; 57(8):PL87-90. PMID: 7637545.
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  43. Gao Y, Gumusel B, Koves G, Prasad A, Hao Q, Hyman A, Lippton H. Agmatine: a novel endogenous vasodilator substance. Life Sci. 1995; 57(8):PL83-6. PMID: 7637544.
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  44. Wang JF, Gao YQ, Lippton H, Hyman A, Spitzer JJ. The roles of nitric oxide and hydrogen peroxide production in lipopolysaccharide-induced intestinal damage. Shock. 1994 Sep; 2(3):185-91. PMID: 7743348.
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  45. Erdemli O, Hao Q, Cai B, Lippton HL, Hyman A. Influence of nifedipine, verapamil and diltiazem on pulmonary vascular resistance and vasoconstrictors in cats. Arch Int Pharmacodyn Ther. 1994 Sep-Oct; 328(2):165-79. PMID: 7535994.
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  46. Lin B, Gao Y, Chang JK, Heaton J, Hyman A, Lippton H. An adrenomedullin fragment retains the systemic vasodepressor activity of rat adrenomedullin. Eur J Pharmacol. 1994 Jul 21; 260(1):1-4. PMID: 7957618.
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  47. Cai B, Hao Q, Greenberg SS, deBoisblanc B, Gillott D, Goharderakhshan R, Summer WR, Hyman A, Lippton H. Differential effects of pinacidil and cromakalim on vascular relaxation and sympathetic neurotransmission. Can J Physiol Pharmacol. 1994 Jul; 72(7):801-10. PMID: 7828089.
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  48. Lippton H, Chang JK, Hao Q, Summer W, Hyman AL. Adrenomedullin dilates the pulmonary vascular bed in vivo. J Appl Physiol (1985). 1994 May; 76(5):2154-6. PMID: 8063680.
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  49. Taheri PA, Lippton HL, Force SD, Franklin EW, Hyman AL, Flint LM, Ferrara JJ. Analysis of regional hemodynamic regulation in response to scald injury. J Clin Invest. 1994 Jan; 93(1):147-54. PMID: 8282781; PMCID: PMC293747.
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  50. Lippton H, Gao Y, Lin B, Heaton J, Ferrara J, DeVito M, Granger T, Pigott J, Chang JK, Hyman A. Prodepin: a new product of the adrenomedullin (ADM) gene has systemic vasodilator activity. Life Sci. 1994; 54(23):PL409-12. PMID: 8196484.
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  51. Hao Q, Chang JK, Gharavi H, Fortenberry Y, Hyman A, Lippton H. An adrenomedullin (ADM) fragment retains the systemic vasodilator activity of human ADM. Life Sci. 1994; 54(16):PL265-70. PMID: 8152335.
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  52. Lippton HL, Hauth TA, Cohen GA, Hyman AL. Functional evidence for different endothelin receptors in the lung. J Appl Physiol (1985). 1993 Jul; 75(1):38-48. PMID: 8376289.
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  53. Greenberg S, Xie J, Wang Y, Cai B, Kolls J, Nelson S, Hyman A, Summer WR, Lippton H. Tumor necrosis factor-alpha inhibits endothelium-dependent relaxation. J Appl Physiol (1985). 1993 May; 74(5):2394-403. PMID: 8335573.
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  54. Perret M, Broussard H, LeGros T, Burns A, Chang JK, Summer W, Hyman A, Lippton H. The effect of adrenomedullin on the isolated heart. Life Sci. 1993; 53(22):PL377-9. PMID: 8231646.
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  55. Lippton HL, Hao Q, Hyman A. L-NAME enhances pulmonary vasoconstriction without inhibiting EDRF-dependent vasodilation. J Appl Physiol (1985). 1992 Dec; 73(6):2432-9. PMID: 1490955.
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  56. McMahon TJ, Hood JS, Nossaman BD, Hyman AL, Kadowitz PJ. Characterization of thromboxane receptor blocking effects of SQ 29548 in the feline pulmonary vascular bed. J Appl Physiol (1985). 1992 Mar; 72(3):1194-200. PMID: 1533211.
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  57. Lippton HL, Hao Q, Hauth T, Hyman A. Mechanisms of signal transduction for adenosine and ATP in pulmonary vascular bed. Am J Physiol. 1992 Mar; 262(3 Pt 2):H926-9. PMID: 1348400.
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  58. Hyman AL, Lippton HL, Kadowitz PJ. Methylene blue prevents hypoxic pulmonary vasoconstriction in cats. Am J Physiol. 1991 Feb; 260(2 Pt 2):H586-92. PMID: 1671738.
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  59. Lippton HL, Cohen GA, McMurtry IF, Hyman AL. Pulmonary vasodilation to endothelin isopeptides in vivo is mediated by potassium channel activation. J Appl Physiol (1985). 1991 Feb; 70(2):947-52. PMID: 1902460.
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  60. Lippton HL, Ohlstein EH, Summer WR, Hyman AL. Analysis of responses to endothelins in the rabbit pulmonary and systemic vascular beds. J Appl Physiol (1985). 1991 Jan; 70(1):331-41. PMID: 2010389.
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  61. Lippton HL, Cohen GA, Knight M, McMurtry IF, Gillot D, Arena F, Summer W, Hyman AL. Evidence for distinct endothelin receptors in the pulmonary vascular bed in vivo. J Cardiovasc Pharmacol. 1991; 17 Suppl 7:S370-3. PMID: 1725383.
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  62. Hyman AL, Lippton HL, Kadowitz PJ. Analysis of pulmonary vascular responses in cats to sympathetic nerve stimulation under elevated tone conditions. Evidence that neuronally released norepinephrine acts on alpha 1-, alpha 2-, and beta 2-adrenoceptors. Circ Res. 1990 Oct; 67(4):862-70. PMID: 1976453.
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  63. Le Monnier de Gouville AC, Lippton H, Cohen G, Cavero I, Hyman A. Vasodilator activity of endothelin-1 and endothelin-3: rapid development of cross-tachyphylaxis and dependence on the rate of endothelin administration. J Pharmacol Exp Ther. 1990 Sep; 254(3):1024-8. PMID: 2118569.
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  64. Brinker MR, Lippton HL, Cook SD, Hyman AL. Pharmacological regulation of the circulation of bone. J Bone Joint Surg Am. 1990 Aug; 72(7):964-75. PMID: 2166739.
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  65. Le Monnier de Gouville AC, Mondot S, Lippton H, Hyman A, Cavero I. Hemodynamic and pharmacological evaluation of the vasodilator and vasoconstrictor effects of endothelin-1 in rats. J Pharmacol Exp Ther. 1990 Jan; 252(1):300-11. PMID: 2405151.
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  66. Hyman AL, Kadowitz PJ. Influence of tone on responses to acetylcholine in the rabbit pulmonary vascular bed. J Appl Physiol (1985). 1989 Oct; 67(4):1388-94. PMID: 2793740.
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  67. Hyman AL, Kadowitz PJ. Analysis of responses to sympathetic nerve stimulation in the feline pulmonary vascular bed. J Appl Physiol (1985). 1989 Jul; 67(1):371-6. PMID: 2569455.
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  68. Neely CF, Kadowitz PJ, Lippton H, Neiman M, Hyman AL. Adenosine does not mediate the pulmonary vasodilator response of adenosine 5'-triphosphate in the feline pulmonary vascular bed. J Pharmacol Exp Ther. 1989 Jul; 250(1):170-6. PMID: 2501475.
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  69. Kadowitz PJ, Lippton HL, Bellan JA, Hyman AL. Nisoldipine inhibits vasoconstrictor responses in the cat pulmonary vascular bed. J Appl Physiol (1985). 1989 Jun; 66(6):2885-90. PMID: 2473060.
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  70. Hyman AL, Kadowitz PJ, Lippton HL. Methylene blue selectively inhibits pulmonary vasodilator responses in cats. J Appl Physiol (1985). 1989 Mar; 66(3):1513-7. PMID: 2468643.
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  71. Lippton HL, Hauth TA, Summer WR, Hyman AL. Endothelin produces pulmonary vasoconstriction and systemic vasodilation. J Appl Physiol (1985). 1989 Feb; 66(2):1008-12. PMID: 2565328.
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  72. McNamara DB, Kerstein MD, Harrington JK, Bellan JA, Graybar GB, Hyman AL, Kadowitz PJ. Determination of the effects of inhibition of pulmonary thromboxane A2 synthase activity, in vivo and in vitro. Adv Prostaglandin Thromboxane Leukot Res. 1989; 19:531-4. PMID: 2526532.
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  73. Given MB, Lowe RF, Lippton H, Hyman AL, Sander GE, Giles TD. Hemodynamic actions of endothelin in conscious and anesthetized dogs. Peptides. 1989 Jan-Feb; 10(1):41-4. PMID: 2664727.
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  74. Kadowitz PJ, McNamara DB, Tilden SJ, Hyman AL, Underwood DC. Inhibition of thromboxane responses in the airway of the cat by SQ29,548 and OKY 1581. Adv Prostaglandin Thromboxane Leukot Res. 1989; 19:535-8. PMID: 2526533.
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  75. Lippton H, Goff J, Hyman A. Effects of endothelin in the systemic and renal vascular beds in vivo. Eur J Pharmacol. 1988 Oct 11; 155(1-2):197-9. PMID: 3072211.
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  76. Hyman AL, Dempesy CW, Fontana C, Richardson DE, Rieck RW, Kadowitz PJ. Pulmonary vascular responses to forebrain stimulation in the cat. Circ Res. 1988 Sep; 63(3):493-501. PMID: 3409482.
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  77. Mayeux PR, Agrawal KC, Tou JS, King BT, Lippton HL, Hyman AL, Kadowitz PJ, McNamara DB. The pharmacological effects of allicin, a constituent of garlic oil. Agents Actions. 1988 Aug; 25(1-2):182-90. PMID: 2847508.
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  78. Lippton HL, Lepak K, Cohen G, Roland P, Kadowitz PJ, Hyman AL. Vasodilator activity of human alpha-calcitonin gene-related peptide in the feline mesenteric vascular bed. Am J Hypertens. 1988 Jul; 1(3 Pt 3):124S-126S. PMID: 3137942.
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  79. Hyman AL, Kadowitz PJ. Tone-dependent responses to acetylcholine in the feline pulmonary vascular bed. J Appl Physiol (1985). 1988 May; 64(5):2002-9. PMID: 3391898.
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  80. Waring PH, Hyman AL, Nandiwada PA, Kadowitz PJ. Influence of OKY-1581 on responses to arachidonic acid in the feline pulmonary vascular bed. Prostaglandins Leukot Essent Fatty Acids. 1988 Mar; 31(3):117-22. PMID: 3131783.
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  81. Kadowitz PJ, McNamara DB, Hyman AL. Cardiopulmonary responses to leukotrienes. Ann N Y Acad Sci. 1988; 524:142-52. PMID: 3132880.
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  82. Kadowitz PJ, Armstead WM, Roland PY, Hyman AL, Lippton HL. Inhibitory effects of diltiazem on vasoconstrictor responses in the cat. J Pharmacol Exp Ther. 1988 Jan; 244(1):84-90. PMID: 2891847.
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  83. Rush DS, Kerstein MD, Bellan JA, Knoop SM, Mayeux PR, Hyman AL, Kadowitz PJ, McNamara DB. Prostacyclin, thromboxane A2, and prostaglandin E2 formation in atherosclerotic human carotid artery. Arteriosclerosis. 1988 Jan-Feb; 8(1):73-8. PMID: 3277612.
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  84. Lippton HL, Armstead WM, Hyman AL, Kadowitz PJ. Influence of calcium-entry blockade on vasoconstrictor responses in feline mesenteric vascular bed. Circ Res. 1987 Oct; 61(4):570-80. PMID: 2443268.
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  85. Underwood DC, Kriseman T, McNamara DB, Hyman AL, Kadowitz PJ. Blockade of thromboxane responses in the airway of the cat by SQ 29,548. J Appl Physiol (1985). 1987 Jun; 62(6):2193-200. PMID: 2440845.
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  86. Tilden SJ, Underwood DC, Cowen KH, Wegmann MJ, Graybar GB, Hyman AL, McNamara DB, Kadowitz PJ. Effects of OKY 1581 on bronchoconstrictor responses to arachidonic acid and PGH2. J Appl Physiol (1985). 1987 May; 62(5):2066-74. PMID: 2954941.
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  87. Armstead WM, Lippton HL, Hyman AL, Kadowitz PJ. Influence of nisoldipine on vascular resistance and vasoconstrictor responses in cats. Am J Physiol. 1987 Apr; 252(4 Pt 2):H816-25. PMID: 2436491.
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  88. Lippton HL, Armstead WM, Hyman AL, Kadowitz PJ. Characterization of the vasoconstrictor activity of indomethacin in the mesenteric vascular bed of the cat. Prostaglandins Leukot Med. 1987 Apr; 27(1):81-91. PMID: 3473508.
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  89. Kriseman T, Underwood DC, Hyman AL, Kadowitz PJ. Analysis of airway responses to A23187 in the cat. J Pharmacol Exp Ther. 1986 Nov; 239(2):395-9. PMID: 3095538.
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  90. Hyman AL, Lippton HL, Kadowitz PJ. Nature of alpha 1 and postjunctional alpha 2 adrenoceptors in the pulmonary vascular bed. Fed Proc. 1986 Aug; 45(9):2336-40. PMID: 3015686.
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  91. McNamara DB, Donath GR, Kadowitz PJ, Hyman AL, Rush DS, Kerstein MD. Prostacyclin synthetase activity in human diabetic and nondiabetic vascular tissue. J Vasc Surg. 1986 Jul; 4(1):63-7. PMID: 3522943.
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  92. Hyman AL, Kadowitz PJ. Enhancement of alpha- and beta-adrenoceptor responses by elevations in vascular tone in pulmonary circulation. Am J Physiol. 1986 Jun; 250(6 Pt 2):H1109-16. PMID: 2872820.
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  93. Guinee DG, McNamara DB, Ignarro LJ, Hyman AL, Kadowitz PJ. Arachidonic acid and acetylcholine induced relaxation of bovine coronary artery: effect of indomethacin and methylene blue. Can J Cardiol. 1986 May-Jun; 2(3):170-5. PMID: 3087607.
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  94. Graybar GB, Harrington JK, Cowen KH, Spannhake EW, Hyman AL, McNamara DB, Kadowitz PJ. Cyclooxygenase mediated airway response to leukotriene D4 in the cat. Prostaglandins. 1986 Jan; 31(1):167-77. PMID: 3081968.
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  95. Hyman AL, Kadowitz PJ. Evidence for existence of postjunctional alpha 1- and alpha 2-adrenoceptors in cat pulmonary vascular bed. Am J Physiol. 1985 Oct; 249(4 Pt 2):H891-8. PMID: 2864862.
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  96. Ignarro LJ, Harbison RG, Wood KS, Wolin MS, McNamara DB, Hyman AL, Kadowitz PJ. Differences in responsiveness of intrapulmonary artery and vein to arachidonic acid: mechanism of arterial relaxation involves cyclic guanosine 3':5'-monophosphate and cyclic adenosine 3':5'-monophosphate. J Pharmacol Exp Ther. 1985 Jun; 233(3):560-9. PMID: 2989487.
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  97. Nandiwada PA, Kadowitz PJ, Said SI, Mojarad M, Hyman AL. Pulmonary vasodilator responses to vasoactive intestinal peptide in the cat. J Appl Physiol (1985). 1985 May; 58(5):1723-8. PMID: 3997734.
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  98. Lippton HL, Horwitz PM, McNamara DB, Ignarro LJ, Landry AZ, Hyman AL, Kadowitz PJ. The effects of amrinone on human platelet aggregation: evidence that amrinone does not act through a cyclic nucleotide mechanism in platelet rich plasma. Prostaglandins Leukot Med. 1985 May; 18(2):193-204. PMID: 3925461.
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  99. Hyman AL, Lippton HL, Kadowitz PJ. Autonomic regulation of the pulmonary circulation. J Cardiovasc Pharmacol. 1985; 7 Suppl 3:S80-95. PMID: 2409403.
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  100. Kadowitz PJ, McNamara DB, Hyman AL. Pulmonary venous responses to leukotrienes. Prog Clin Biol Res. 1985; 199:247-57. PMID: 4070315.
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  101. Armstead WM, Lippton HL, Hyman AL, Kadowitz PJ. Analysis of adrenergic responses in the mesenteric vascular bed of the cat; evidence that vascular beta 2-adrenoceptors are innervated. Can J Physiol Pharmacol. 1984 Dec; 62(12):1470-8. PMID: 6099218.
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  102. Kadowitz PJ, Hyman AL. Analysis of responses to leukotriene D4 in the pulmonary vascular bed. Circ Res. 1984 Nov; 55(5):707-17. PMID: 6435907.
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  103. Saroyan RM, Kerstein MD, Kadowitz PJ, Hyman AL, McNamara DB. Prostacyclin synthetase activity in diabetic human venous tissue. Surgery. 1984 Aug; 96(2):179-83. PMID: 6379956.
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  104. Lippton HL, Nandiwada PA, Hyman AL, Kadowitz PJ. Influence of cyclooxygenase blockade on responses to isoproterenol, bradykinin and nitroglycerin in the feline pulmonary vascular bed. Prostaglandins. 1984 Aug; 28(2):253-70. PMID: 6438697.
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  105. Hyman AL, Kadowitz PJ. Vasodilator therapy for pulmonary hypertensive disorders. Chest. 1984 Feb; 85(2):145-7. PMID: 6692692.
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  106. Lippton HL, Armstead WM, Hyman AL, Kadowitz PJ. Vasoconstrictor effects of leukotrienes C4 and D4 in the feline mesenteric vascular bed. Prostaglandins. 1984 Feb; 27(2):233-43. PMID: 6425992.
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  107. McNamara DB, Hussey JL, Kerstein MD, Rosenson RS, Hyman AL, Kadowitz PJ. Modulation of prostacyclin synthetase and unmasking of PGE2 isomerase in bovine coronary arterial microsomes. Biochem Biophys Res Commun. 1984 Jan 13; 118(1):33-9. PMID: 6365099.
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  108. Edwards JC, Ignarro LJ, Hyman AL, Kadowitz PJ. Relaxation of intrapulmonary artery and vein by nitrogen oxide-containing vasodilators and cyclic GMP. J Pharmacol Exp Ther. 1984 Jan; 228(1):33-42. PMID: 6319670.
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  109. Kerstein MD, Saroyan M, McMullen-Laird M, Hyman AL, Kadowitz P, McNamara DB. Metabolism of prostaglandins in human saphenous vein. J Surg Res. 1983 Aug; 35(2):91-100. PMID: 6350708.
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  110. Nandiwada PA, Hyman AL, Kadowitz PJ. Pulmonary vasodilator responses to vagal stimulation and acetylcholine in the cat. Circ Res. 1983 Jul; 53(1):86-95. PMID: 6407775.
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  111. Mellion BT, Ignarro LJ, Myers CB, Ohlstein EH, Ballot BA, Hyman AL, Kadowitz PJ. Inhibition of human platelet aggregation by S-nitrosothiols. Heme-dependent activation of soluble guanylate cyclase and stimulation of cyclic GMP accumulation. Mol Pharmacol. 1983 May; 23(3):653-64. PMID: 6135148.
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  112. Kadowitz PJ, Nandiwada PA, Spannhake EW, Rosenson RS, McNamara DB, Hyman AL. Pulmonary vascular responses to thromboxane A2 as unmasked by OKY-1581. A novel inhibitor of thromboxane synthesis. Chest. 1983 May; 83(5 Suppl):72S-74S. PMID: 6404609.
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  113. Kadowitz PJ, Hyman AL. Pulmonary vascular responses to histamine in sheep. Am J Physiol. 1983 Mar; 244(3):H423-8. PMID: 6829784.
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  114. Spannhake EW, Levin JL, Hyman AL, Kadowitz PJ. In vivo metabolism of dihomo-gamma-linolenic acid to bronchoactive products in the canine lung. Prostaglandins Leukot Med. 1983 Feb; 10(2):123-32. PMID: 6405393.
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  115. Spannhake EW, Colombo JL, Craigo PA, McNamara DB, Hyman AL, Kadowitz PJ. Evidence for modification of pulmonary cyclooxygenase activity by endotoxin in the dog. J Appl Physiol Respir Environ Exerc Physiol. 1983 Jan; 54(1):191-8. PMID: 6402470.
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  116. Levin JL, Spannhake EW, Hyman AL, Kadowitz PJ. Analysis of airway responses to dihomo-gamma-linolenic acid in the cat. J Pharmacol Exp Ther. 1982 Oct; 223(1):169-76. PMID: 6811730.
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  117. Kadowitz PJ, Hyman AL. Hydralazine and the treatment of primary pulmonary hypertension. N Engl J Med. 1982 Jun 03; 306(22):1357-9. PMID: 7070463.
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  118. Kadowitz PJ, Lippton HL, McNamara DB, Spannhake EW, Hyman AL. Action and metabolism of prostaglandins in the pulmonary circulation. Adv Prostaglandin Thromboxane Leukot Res. 1982; 10:333-56. PMID: 6216787.
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  119. Spannhake EW, Hyman AL, Kadowitz PJ. Bronchoactive metabolites of arachidonic acid and their role in airway function. Prostaglandins. 1981 Dec; 22(6):1013-26. PMID: 6801729.
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  120. Kadowitz PJ, Knight DS, Greenberg S, Hyman AL. Structure and function of the adrenergic nerves in the canine pulmonary vascular bed. Methods Find Exp Clin Pharmacol. 1981 Nov-Dec; 3(6):347-59. PMID: 7329159.
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  121. Knight DS, Ellison JP, Hibbs RG, Hyman AL, Kadowitz PJ. A light and electron microscopic study of the innervation of pulmonary arteries in the cat. Anat Rec. 1981 Nov; 201(3):513-21. PMID: 7305032.
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  122. Hyman AL, Higashida RT, Spannhake EW, Kadowitz PJ. Pulmonary vasoconstrictor responses to graded decreases in precapillary blood PO2 in intact-chest cat. J Appl Physiol Respir Environ Exerc Physiol. 1981 Oct; 51(4):1009-16. PMID: 7298414.
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  123. Ignarro LJ, Lippton H, Edwards JC, Baricos WH, Hyman AL, Kadowitz PJ, Gruetter CA. Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates. J Pharmacol Exp Ther. 1981 Sep; 218(3):739-49. PMID: 6115052.
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  124. Hyman AL, Mathé AA, Lippton HL, Kadowitz PJ. Prostaglandins and the lung. Med Clin North Am. 1981 Jul; 65(4):789-808. PMID: 7024664.
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  125. Kadowitz PJ, Gruetter CA, Spannhake EW, Hyman AL. Pulmonary vascular responses to prostaglandins. Fed Proc. 1981 May 15; 40(7):1991-6. PMID: 7014258.
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  126. Lippton HL, Meyer RL, Parey SE, Hyman AL, Kadowitz PJ. Analysis of responses to dopamine in the mesenteric vascular bed of the cat. Arch Int Pharmacodyn Ther. 1981 May; 251(1):136-49. PMID: 6114715.
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  127. Mellion BT, Ignarro LJ, Ohlstein EH, Pontecorvo EG, Hyman AL, Kadowitz PJ. Evidence for the inhibitory role of guanosine 3', 5'-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators. Blood. 1981 May; 57(5):946-55. PMID: 6111365.
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  128. She HS, McNamara DB, Spannhake EW, Hyman AL, Kadowitz PJ. Metabolism of prostaglandin endoperoxide by microsomes from cat lung. Prostaglandins. 1981 Apr; 21(4):531-9. PMID: 6894797.
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  129. Kadowitz PJ, Nandiwada P, Gruetter CA, Ignarro LJ, Hyman AL. Pulmonary vasodilator responses to nitroprusside and nitroglycerin in the dog. J Clin Invest. 1981 Mar; 67(3):893-902. PMID: 6782123; PMCID: PMC370641.
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  130. Hyman AL, Nandiwada P, Knight DS, Kadowitz PJ. Pulmonary vasodilator responses to catecholamines and sympathetic nerve stimulation in the cat. Evidence that vascular beta-2 adrenoreceptors are innervated. Circ Res. 1981 Mar; 48(3):407-15. PMID: 6257422.
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  131. Spannhake EW, Levin JL, Hyman AL, Kadowitz PJ. 6-keto-PGE1 exhibits more potent bronchodilatory activity in the cat than its precursor, PGI2. Prostaglandins. 1981 Feb; 21(2):267-75. PMID: 7012934.
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  132. Gruetter CA, Ignarro LJ, Hyman AL, Kadowitz PJ. Contractile effects of 5-hydroxytryptamine in isolated intrapulmonary arteries and veins. Can J Physiol Pharmacol. 1981 Feb; 59(2):157-62. PMID: 7225942.
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  133. Knight DS, Hyman AL, Kadowitz PJ. Innervation of intrapulmonary airway smooth muscle of the dog, monkey and baboon. J Auton Nerv Syst. 1981 Feb; 3(1):31-43. PMID: 7264194.
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  134. Greenberg S, Kadowitz PJ, Hyman A, Curron FA. Adrenergic mechanisms in canine intralobar pulmonary arteries and veins. Am J Physiol. 1981 Feb; 240(2):H274-85. PMID: 6258452.
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  135. Spannhake EW, Levin JL, McNamara DB, Hyman AL, Kadowitz PJ. In vivo synthesis of airway-active agents from arachidonic acid. Bull Eur Physiopathol Respir. 1981; 17(4):523-30. PMID: 6120017.
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  136. Lippton HL, Chapnick BM, Hyman AL, Glass FL, Kadowitz PJ. The influence of indomethacin on vasodilator responses to bradykinin and nitroglycerin in the cat. Peptides. 1981; 2(2):165-9. PMID: 6794012.
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  137. Kadowitz PJ, McNamara DB, She HS, Spannhake EW, Hyman AL. Arachidonic acid responses in the lung. Bull Eur Physiopathol Respir. 1981; 17(4):659-73. PMID: 6799028.
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  138. McNamara DB, Kadowitz PJ, Hyman AL, Ignarro LJ. Adenosine 3',5'-monophosphate formation by preparations of rat liver soluble guanylate cyclase activated with nitric oxide, nitrosyl ferroheme, S-nitrosothiols, and other nitroso compounds. Can J Physiol Pharmacol. 1980 Dec; 58(12):1446-56. PMID: 6113040.
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  139. Gruetter DY, Gruetter CA, Barry BK, Baricos WH, Hyman AL, Kadowitz PJ, Ignarro LJ. Activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside, and nitrosoguanidine--inhibition by calcium, lanthanum, and other cations, enhancement by thiols. Biochem Pharmacol. 1980 Nov 01; 29(21):2943-50. PMID: 6109533.
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  140. Spannhake EW, Levin JL, Mellion BT, Gruetter CA, Hyman AL, Kadowitz PJ. Reversal of 5HT-induced bronchoconstriction by PGI2: distribution of central and peripheral actions. J Appl Physiol Respir Environ Exerc Physiol. 1980 Sep; 49(3):521-7. PMID: 7009520.
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  141. Feigen LP, Chapnick BM, Hyman AL, King L, Marascalco B, Kadowitz PJ. Peripheral vasodilator effects of prostaglandins: comparison of 6-keto-prostaglandin E1 with prostacyclin and escape from prostaglandin E2 in the mesenteric vascular bed. J Pharmacol Exp Ther. 1980 Sep; 214(3):528-34. PMID: 6995573.
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  142. McNamara DB, Roulet MJ, Gruetter CA, Hyman AL, Kadowitz PJ. Correlation of prostaglandin-induced mitochondrial calcium release with contraction in bovine intrapulmonary vein. Prostaglandins. 1980 Aug; 20(2):311-20. PMID: 7413994.
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  143. Hyman AL, Spannhake EW, Kadowitz PJ. Divergent responses to arachidonic acid in the feline pulmonary vascular bed. Am J Physiol. 1980 Jul; 239(1):H40-6. PMID: 7396016.
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  144. Hyman AL, Kadowitz PJ. Vasodilator actions of prostaglandin 6-keto-E1 in the pulmonary vascular bed. J Pharmacol Exp Ther. 1980 Jun; 213(3):468-72. PMID: 7193724.
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  145. Kadowitz PJ, Hyman AL. Comparative effects of thromboxane B2 on the canine and feline pulmonary vascular bed. J Pharmacol Exp Ther. 1980 May; 213(2):300-5. PMID: 7365689.
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  146. Nandiwada P, Hyman AL, Feigen LP, Kadowitz PJ. Cardiopulmonary actions of prostaglandin 6-keto-E1 in the anesthetized dog. Arch Int Pharmacodyn Ther. 1980 May; 245(1):118-28. PMID: 7190813.
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  147. Kadowitz PJ, Spannhake EW, Hyman AL. Prostaglandins evoke a whole variety of responses in the lung. Environ Health Perspect. 1980 Apr; 35:181-90. PMID: 6997027.
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  148. Spannhake EW, Hyman AL, Kadowitz PJ. Dependence of the airway and pulmonary vascular effects of arachidonic acid upon route and rate of administration. J Pharmacol Exp Ther. 1980 Mar; 212(3):584-90. PMID: 7359357.
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  149. Lippton HL, Chapnick BM, Hyman AL, Kadowitz PJ. Inhibition of vasoconstrictor responses by 6-keto-PGE1 in the feline mesenteric vascular bed. Prostaglandins. 1980 Feb; 19(2):299-310. PMID: 6992227.
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  150. Hyman AL, Spannhake EW, Kadowitz PJ. Disparate actions of arachidonic acid on feline pulmonary vascular bed. Adv Prostaglandin Thromboxane Res. 1980; 7:765-7. PMID: 7369042.
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  151. Spannhake EW, Hyman AL, Kadowitz PJ. Dissimilar in vivo effects of arachidonic acid on the canine pulmonary vascular bed and airways. Adv Prostaglandin Thromboxane Res. 1980; 7:937-41. PMID: 7369059.
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  152. Lippton HL, Chapnick BM, Hyman AL, Kadowitz PJ. Influence of prostacyclin on sympathetic neurotransmission in the feline intestinal vascular bed. Adv Prostaglandin Thromboxane Res. 1980; 8:1249-53. PMID: 6246775.
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  153. Kadowitz PJ, Spannhake EW, Levin JL, Hyman AL. Differential actions of the prostaglandins on the pulmonary vascular bed. Adv Prostaglandin Thromboxane Res. 1980; 7:731-43. PMID: 6989201.
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  154. Lippton HL, Chapnick BM, Hyman AL, Kadowitz PJ. Inhibition of vasoconstrictor responses by prostacyclin (PGI2) in the feline mesenteric vascular bed. Arch Int Pharmacodyn Ther. 1979 Oct; 241(2):214-23. PMID: 393194.
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  155. McNamara DB, Roulet MJ, Hyman AL, Kadowitz PJ. Characterization of the energy-dependent calcium binding of a mitochondrial fraction isolated from bovine intrapulmonary vein. Can J Physiol Pharmacol. 1979 Oct; 57(10):1107-13. PMID: 509364.
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  156. Lippton HL, Paustian PW, Mellion BT, Nelson PK, Feigen LP, Chapnick BM, Hyman AL, Kadowitz PJ. Cardiovascular actions of prostacyclin (PGI2) in the cat. Arch Int Pharmacodyn Ther. 1979 Sep; 241(1):121-30. PMID: 393193.
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  157. Hyman AL, Kadowitz PJ. Pulmonary vasodilator activity of prostacyclin (PGI2) in the cat. Circ Res. 1979 Sep; 45(3):404-9. PMID: 110490.
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  158. Hyman AL, Mathe AA, Leslie CA, Matthews CC, Bennett JT, Spannhake EW, Kadowitz PJ. Modification of pulmonary vascular responses to arachidonic acid by alterations in physiologic state. J Pharmacol Exp Ther. 1978 Nov; 207(2):388-401. PMID: 361946.
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  159. Spannhake EW, Mercier RR, Hyman AL, Kadowitz PJ. 15(S)-15-Methyl prostaglandin F2alpha elicits marked peripheral airway constriction in the intact dog. J Pharmacol Exp Ther. 1978 Oct; 207(1):83-91. PMID: 702354.
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  160. Chapnick BM, Feigen LP, Hyman AL, Kadowitz PJ. Differential effects of prostaglandins in the mesenteric vascular bed. Am J Physiol. 1978 Sep; 235(3):H326-32. PMID: 358842.
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  161. Kadowitz PJ, Chapnick BM, Feigen LP, Hyman AL, Nelson PK, Spannhake EW. Pulmonary and systemic vasodilator effects of the newly discovered prostaglandin, PGI2. J Appl Physiol Respir Environ Exerc Physiol. 1978 Sep; 45(3):408-13. PMID: 359514.
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  162. Hyman AL, Kadowitz PJ, Lands WE, Crawford CG, Fried J, Barton J. Coronary vasodilator activity of 13,14-dehydroprostacyclin methyl ester: comparison with prostacyclin and other prostanoids. Proc Natl Acad Sci U S A. 1978 Jul; 75(7):3522-6. PMID: 356056; PMCID: PMC392810.
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  163. Gruetter CA, McNamara DB, Hyman AL, Kadowitz PJ. Contractile responses of intrapulmonary vessels from three species to arachidonic acid and an epoxymethano analog of PGH2. Can J Physiol Pharmacol. 1978 Apr; 56(2):206-15. PMID: 638873.
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  164. Spannhake EW, Lemen RJ, Wegmann MJ, Hyman AL, Kadowitz PJ. Analysis of airway effects of a PGH2 analog in the anesthetized dog. J Appl Physiol Respir Environ Exerc Physiol. 1978 Mar; 44(3):406-15. PMID: 632181.
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  165. Spannhake EW, Lemen RJ, Wegmann MJ, Hyman AL, Kadowitz PJ. Effects of arachidonic acid and prostaglandins on lung function in the intact dog. J Appl Physiol Respir Environ Exerc Physiol. 1978 Mar; 44(3):397-405. PMID: 632180.
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  166. Gruetter CA, McNamara DB, Hyman AL, Kadowitz PJ. Contractile effects of a PGH2 analog and PGD2 on intrapulmonary vessels. Am J Physiol. 1978 Feb; 234(2):H139-45. PMID: 623314.
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  167. Hyman AL, Spannhake EW, Chapnick BM, McNamara DB, Mathe AA, Kadowitz PJ. Effect of dihomo-gamma-linolenic acid on the canine pulmonary vascular bed. Am J Physiol. 1978 Feb; 234(2):H133-8. PMID: 623313.
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  168. Hyman AL, Spannhake EW, Kadowitz PJ. Prostaglandins and the lung. Am Rev Respir Dis. 1978 Jan; 117(1):111-36. PMID: 339796.
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  169. Kadowitz PJ, Spannhake EW, Greenberg S, Feigen LP, Hyman A. Comparative effects of arachidonic acid, bisenoic prostaglandins, and an endoperoxide analog on the canine pulmonary vascular bed. Can J Physiol Pharmacol. 1977 Dec; 55(6):1369-77. PMID: 597784.
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  170. Hyman AL, Chapnick BM, Kadowitz PJ, Lands WE, Crawford CG, Fried J, Barton J. Unusual pulmonary vasodilator activity of 13,14-dehydroprostacyclin methyl ester: comparison with endoperoxides and other prostanoids. Proc Natl Acad Sci U S A. 1977 Dec; 74(12):5711-5. PMID: 414226; PMCID: PMC431863.
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  171. Kadowitz PJ, Gruetter CA, McNamara DB, Gorman RR, Spannhake EW, Hyman AL. Comparative effects of endoperoxide PGH2 and an analog on the pulmonary vascular bed. J Appl Physiol Respir Environ Exerc Physiol. 1977 Jun; 42(6):953-8. PMID: 881396.
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  172. Chapnick BM, Paustian PW, Feigen LP, Joiner PD, Hyman AL, Kadowitz PJ. Influence of inhibitors of prostaglandin synthesis on renal vascular resistance and on renal vascular responses to vasopressor and vasodilator agents in the cat. Circ Res. 1977 Apr; 40(4):348-54. PMID: 403030.
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  173. Kadowitz PJ, Hyman AL. Influence of a prostaglandin endoperoxide analogue on the canine pulmonary vascular bed. Circ Res. 1977 Mar; 40(3):282-7. PMID: 837475.
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  174. Kadowitz PJ, Spannhake EW, Knight DS, Hyman AL. Vasoactive hormones in the pulmonary vascular bed. Chest. 1977 Feb; 71(2 suppl):257-61. PMID: 836364.
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  175. Knight DS, Hyman AL, Ellison JP, Kadowitz PJ. Catecholamine mechanisms in the canine and feline lung. Chest. 1977 Feb; 71(2 suppl):262-3. PMID: 836366.
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  176. Paustian PW, Chapnick BM, Feigen LP, Hyman AL, Kadowitz PJ. Effects of 13, 14-dehydroprostacyclin methyl ester on the feline intestinal vascular bed. Prostaglandins. 1977; 14(6):1141-52. PMID: 341229.
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  177. Goldberg MR, Chapnick BM, Joiner PD, Hyman AL, Kadowitz PJ. Influence of inhibitors of prostaglandin synthesis on venoconstrictor responses to bradykinin. J Pharmacol Exp Ther. 1976 Aug; 198(2):357-65. PMID: 948031.
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  178. Kadowitz PJ, Knight DS, Hibbs RG, Ellison JP, Joiner PD, Brody MJ, Hyman AL. Influence of 5- and 6-hydroxydopamine on adrenergic transmission and nerve terminal morphology in the canine pulmonary vascular bed. Circ Res. 1976 Aug; 39(2):191-9. PMID: 181163.
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  179. Hughes JP, Kadowitz PJ, Hyman AL, Ray JE, Joiner PD. Pharmacology of human isolated colonic circular and longitudinal smooth muscle from cancer and non-cancer patients. Dis Colon Rectum. 1976 Mar; 19(2):120-5. PMID: 1253652.
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  180. Kadowitz PJ, Joiner PD, Greenberg S, Hyman AL. Comparison of the effects of prostaglandins A, E, F, and B on the canine pulmonary vascular bed. Adv Prostaglandin Thromboxane Res. 1976; 1:403-15. PMID: 998434.
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  181. Chapnick BM, Paustian PW, Klainer E, Joiner PD, Hyman AL, Kadowitz PJ. Influence of prostaglandins E, A and F on vasoconstrictor responses to norepinephrine, renal nerve stimulation and angiotensin in the feline kidney. J Pharmacol Exp Ther. 1976 Jan; 196(1):44-52. PMID: 1246015.
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  182. Joiner PD, Kadowitz PJ, Hughes JP, Hyman AL. Actions of prostaglandins E1 and F2alpha on isolated intrapulmonary vascular smooth muscle. Proc Soc Exp Biol Med. 1975 Nov; 150(2):414-21. PMID: 1208557.
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  183. Joiner PD, Kadowitz PJ, Davis LB, Hyman AL. Contractile responses of canine isolated pulmonary lobar arteries and veins to norepinephrine, serotonin, and tyramine. Can J Physiol Pharmacol. 1975 Oct; 53(5):830-8. PMID: 1201488.
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  184. Kadowitz PJ, Chapnick BM, Joiner PD, Hyman AL. Influence of inhibitors of prostaglandin synthesis on the canine pulmonary vascular bed. Am J Physiol. 1975 Oct; 229(4):941-6. PMID: 1190337.
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  185. Hyman AL, Knight DS, Joiner PD, Kadowitz PJ. Bronchopulmonary arterial shunting without anatomic anastomosis in the dog. Circ Res. 1975 Sep; 37(3):285-98. PMID: 1157218.
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  186. Kadowitz PJ, Joiner PD, Hyman AL. Influence of sympathetic stimulation and vasoactive substances on the canine pulmonary veins. J Clin Invest. 1975 Aug; 56(2):354-65. PMID: 1150876; PMCID: PMC436594.
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  187. Goldberg MR, Joiner PD, Hyman AL, Kadowitz PJ. Unusual venoconstrictor effects of angiotensin II. Proc Soc Exp Biol Med. 1975 Jul; 149(3):707-13. PMID: 238217.
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  188. Kadowitz PJ, Joiner PD, Hyman AL. Comparison of the effects of prostaglandins F1alpha, F2alpha, F1beta, and F2beta on the canine pulmonary vascular bed. Proc Soc Exp Biol Med. 1975 Jun; 149(2):356-61. PMID: 1153409.
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  189. Joiner PD, Kadowitz PJ, Hughes JP, Hyman AL. NE and ACh responses of intrapulmonary vessels from dog, swine, sheep, and man. Am J Physiol. 1975 Jun; 228(6):1821-7. PMID: 1155611.
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  190. Kadowitz PJ, Joiner PD, Matthews CS, Hyman AL. Effects of the 15-methyl analogs of prostaglandins E2 and F2alpha on the pulmonary circulation in the intact dog. J Clin Invest. 1975 May; 55(5):937-44. PMID: 1123430; PMCID: PMC301839.
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  191. Kadowitz PJ, Hyman AL. Differential effects of prostaglandins A1 and A2 on pulmonary vascular resistance in the dog. Proc Soc Exp Biol Med. 1975 May; 149(1):282-6. PMID: 1144439.
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  192. Kadowitz PJ, Joiner PD, Hyman AL, George WJ. Influence of prostaglandins E1 and F2alpha on pulmonary vascular resistance, isolated lobar vessels and cyclic nucleotide levels. J Pharmacol Exp Ther. 1975 Mar; 192(3):677-87. PMID: 164534.
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  193. Goldberg MR, Joiner PD, Greenberg S, Hyman AL, Kadowitz PJ. Effects of indomethacin on venoconstrictor responses to bradykinin and norepinephrine. Prostaglandins. 1975 Mar; 9(3):385-90. PMID: 1138295.
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  194. Kadowitz PJ, Joiner PD, Hyman AL. Effect of prostaglandin E2 on pulmonary vascular resistance in intact dog, swine and lamb. Eur J Pharmacol. 1975 Mar; 31(1):72-80. PMID: 1126381.
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  195. Hyman AL, Kadowitz PJ. Effects of alveolar and perfusion hypoxia and hypercapnia on pulmonary vascular resistance in the lamb. Am J Physiol. 1975 Feb; 228(2):397-403. PMID: 235217.
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  196. Kadowitz PJ, Joiner PD, Greenberg S, Hyman AL. Effects of prostaglandins B2 and B1 on the pulmonary circulation in the intact dog. J Pharmacol Exp Ther. 1975 Jan; 192(1):157-65. PMID: 235632.
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  197. Kadowitz PJ, Joiner PD, Hyman AL. Physiological and pharmacological roles of prostaglandins. Annu Rev Pharmacol. 1975; 15:285-306. PMID: 167656.
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  198. Kadowitz PJ, Joiner PD, Hyman AL. Effect of sympathetic nerve stimulation on pulmonary vascular resistance in the intact spontaneously breathing dog. Proc Soc Exp Biol Med. 1974 Oct; 147(1):68-71. PMID: 4438344.
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  199. Kadowitz PJ, Joiner PD, Hyman AL. Influence of prostaglandins E1 and F2a on pulmonary vascular resistance in the sheep. Proc Soc Exp Biol Med. 1974 Apr; 145(4):1258-61. PMID: 4827737.
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  200. Kadowitz PJ, Joiner PD, Hyman AL. Effects of prostaglandins E1 and F2a on the swine pulmonary circulation. Proc Soc Exp Biol Med. 1974 Jan; 145(1):53-8. PMID: 4812870.
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  201. Kadowitz PJ, Joiner PD, Hyman AL. Differential effects of phentolamine and bretylium on pulmonary vascular responses to norepinephrine and nerve stimulation. Proc Soc Exp Biol Med. 1973 Oct 01; 144(1):172-6. PMID: 4771554.
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  202. Kadowitz PJ, Hyman AL. Effect of sympathetic nerve stimulation on pulmonary vascular resistance in the dog. Circ Res. 1973 Feb; 32(2):221-7. PMID: 4685966.
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  203. Pennington DG, Hyman AL, Jaques WE. Pulmonary vascular response to endotoxin in intact dogs. Surgery. 1973 Feb; 73(2):246-55. PMID: 4567841.
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  204. Hyman AL, Pennington DG, Kadowitz PJ. Effect of acute pulmonary edema on pulmonary arterial pressure in intact dogs. Am J Physiol. 1973 Jan; 224(1):35-9. PMID: 4683306.
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  205. Woolverton WC, Hyman AL. Pulmonary embolism: a resume of experimental investigations into the early pulmonary hemodynamic effects of lung emboli. J La State Med Soc. 1972 Apr; 124(4):124-9. PMID: 5018732.
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  206. Hyman AL, Pennington DG, Jaques WE. Pulmonary vascular responses to alloxan. J Pharmacol Exp Ther. 1972 Apr; 181(1):92-7. PMID: 5013158.
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  207. Hyman AL, Woolverton WC. Pulmonary hypertension and acidemia: activation of pressor substances from whole blood fractions. Proc Soc Exp Biol Med. 1971 Oct; 138(1):221-7. PMID: 5125520.
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  208. Hyman AL, Woolverton WC, Pennington DG, Jaques WE. Pulmonary vascular responses to adenosine diphosphate. J Pharmacol Exp Ther. 1971 Sep; 178(3):549-61. PMID: 5571903.
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  209. Pennington DG, Hyman AL, Woolverton WC. Pulmonary vascular responses to selective lung cooling in intact dogs. Proc Soc Exp Biol Med. 1971 Sep; 137(4):1375-80. PMID: 5138466.
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  210. Hyman AL, Woolverton WC, Guth PS, Ichinose H. The pulmonary vasopressor response to decreases in blood pH in intact dogs. J Clin Invest. 1971 May; 50(5):1028-43. PMID: 5552405; PMCID: PMC292025.
    View in: PubMed, PubMed Central
  211. Hyman AL. The effects of lidocaine, hexamethonium and alpha and beta adrenergic blocking agents on the pulmonary veins in intact dogs. J Pharmacol Exp Ther. 1970 Sep; 174(3):487-99. PMID: 5456181.
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  212. Hyman AL. Effects of large increases in pulmonary blood flow on pulmonary venous pressure. J Appl Physiol. 1969 Aug; 27(2):179-85. PMID: 5796304.
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  213. Hyman AL, Sanchez G. Active response of pulmonary veins to distention of a single pulmonary vein in intact dogs. J Lab Clin Med. 1969 Mar; 73(3):476-85. PMID: 5766192.
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  214. Hyman AL. The active responses of pulmonary veins in intact dogs to prostaglandins F2 alpha and E1. J Pharmacol Exp Ther. 1969 Feb; 165(2):267-73. PMID: 5763061.
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  215. Hyman AL. Pulmonary vasoconstriction due to nonocclusive distention of large pulmonary arteries in the dog. Circ Res. 1968 Sep; 23(3):401-13. PMID: 4877676.
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  216. Schramel R, Hyman A, Keller CA, Woolverton W. Congestive atelectasis. J Trauma. 1968 Sep; 8(5):821-6. PMID: 5675606.
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  217. Hyman AL. The effects of bradykinin on the pulmonary veins. J Pharmacol Exp Ther. 1968 May; 161(1):78-87. PMID: 5648503.
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  218. DePasquale NP, Burch GE, Hyman AL. Pulmonary venous responses to immersion hyperthermia and hypothermia. Am Heart J. 1965 Oct; 70(4):486-93. PMID: 5834195.
    View in: PubMed
  219. DEPASQUALE NP, HYMAN AL, BURCH GE. RESPONSE OF THE PULMONARY VEIN TO RAPID BLOOD TRANSFUSION IN INTACT DOGS. J Lab Clin Med. 1965 Jan; 65:122-31. PMID: 14260686.
    View in: PubMed
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