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Fabrisia Ambrosio, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Conkright WR, Beckner ME, Sterczala AJ, Mi Q, Lovalekar M, Sahu A, Krajewski KT, Martin BJ, Flanagan SD, Greeves JP, O'Leary TJ, Wardle SL, Ambrosio F, Nindl BC. Resistance exercise differentially alters extracellular vesicle size and subpopulation characteristics in healthy men and women: an observational cohort study. Physiol Genomics. 2022 09 01; 54(9):350-359. PMID: 35816651.
    Citations:    Fields:    
  2. Iijima H, Gilmer G, Wang K, Sivakumar S, Evans C, Matsui Y, Ambrosio F. Meta-analysis Integrated With Multi-omics Data Analysis to Elucidate Pathogenic Mechanisms of Age-Related Knee Osteoarthritis in Mice. J Gerontol A Biol Sci Med Sci. 2022 07 05; 77(7):1321-1334. PMID: 34979545; PMCID: PMC9255692.
    Citations:    Fields:    Translation:AnimalsCells
  3. Beckner ME, Conkright WR, Mi Q, Martin B, Sahu A, Flanagan SD, Ledford AK, Wright M, Susmarski A, Ambrosio F, Nindl BC. Neuroendocrine, inflammatory, and extracellular vesicle responses during the Navy Special Warfare Screener Selection Course. Physiol Genomics. 2022 08 01; 54(8):283-295. PMID: 35695270; PMCID: PMC9291410.
    Citations:    Fields:    Translation:HumansCells
  4. Beckner ME, Conkright WR, Sahu A, Mi Q, Clemens ZJ, Martin BJ, Flanagan SD, Ferrarelli F, Ambrosio F, Nindl BC. Utility of extracellular vesicles as a potential biological indicator of physiological resilience during military operational stress. Physiol Rep. 2022 04; 10(7):e15219. PMID: 35373929; PMCID: PMC8978596.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  5. Conkright WR, Beckner ME, Sahu A, Mi Q, Clemens ZJ, Lovalekar M, Flanagan SD, Martin BJ, Ferrarelli F, Ambrosio F, Nindl BC. Men and women display distinct extracellular vesicle biomarker signatures in response to military operational stress. J Appl Physiol (1985). 2022 05 01; 132(5):1125-1136. PMID: 35297690; PMCID: PMC9054257.
    Citations: 2     Fields:    Translation:HumansCells
  6. Sahu A, Clemens ZJ, Shinde SN, Sivakumar S, Pius A, Bhatia A, Picciolini S, Carlomagno C, Gualerzi A, Bedoni M, Van Houten B, Lovalekar M, Fitz NF, Lefterov I, Barchowsky A, Koldamova R, Ambrosio F. Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles. Nat Aging. 2021 Dec; 1(12):1148-1161. PMID: 35665306; PMCID: PMC9165723.
    Citations: 5     
  7. Ghuman H, Perry N, Grice L, Gerwig M, Moorhead J, Nitzsche F, Poplawsky AJ, Ambrosio F, Modo M. Physical therapy exerts sub-additive and suppressive effects on intracerebral neural stem cell implantation in a rat model of stroke. J Cereb Blood Flow Metab. 2022 05; 42(5):826-843. PMID: 34826373; PMCID: PMC9254031.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  8. Bourne DA, James I, Wang S, Bliley J, Grahovac T, Mitchell RT, Brown SA, Ambrosio F, Ho J, Lannau B, Kemp PD, Gusenoff J, Rubin JP, Gusenoff J. Treatment of burn contractures with allogeneic human dermal fibroblasts improves Vancouver scar scale: A phase I/II trial. J Plast Reconstr Aesthet Surg. 2021 Dec; 74(12):3443-3476. PMID: 34593339.
    Citations:    Fields:    Translation:HumansCellsCTClinical Trials
  9. Clemens Z, Sivakumar S, Pius A, Sahu A, Shinde S, Mamiya H, Luketich N, Cui J, Dixit P, Hoeck JD, Kreuz S, Franti M, Barchowsky A, Ambrosio F. The biphasic and age-dependent impact of klotho on hallmarks of aging and skeletal muscle function. Elife. 2021 04 20; 10. PMID: 33876724; PMCID: PMC8118657.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  10. Kakar RS, Pastor JV, Moe OW, Ambrosio F, Castaldi D, Sanders LH. Peripheral Klotho and Parkinson's Disease. Mov Disord. 2021 05; 36(5):1274-1276. PMID: 33629770; PMCID: PMC9295462.
    Citations: 1     Fields:    Translation:Humans
  11. Anguiano T, Sahu A, Qian B, Tang WY, Ambrosio F, Barchowsky A. Arsenic Directs Stem Cell Fate by Imparting Notch Signaling Into the Extracellular Matrix Niche. Toxicol Sci. 2020 10 01; 177(2):494-505. PMID: 32647881; PMCID: PMC7548290.
    Citations: 2     Fields:    Translation:AnimalsCells
  12. Sachdev U, Ferrari R, Cui X, Pius A, Sahu A, Reynolds M, Liao H, Sun P, Shinde S, Ambrosio F, Shiva S, Loughran P, Scott M. Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine. Mol Med. 2020 07 08; 26(1):69. PMID: 32641037; PMCID: PMC7341481.
    Citations: 2     Fields:    Translation:AnimalsCellsPHPublic Health
  13. Cheikhi A, Anguiano T, Lasak J, Qian B, Sahu A, Mimiya H, Cohen CC, Wipf P, Ambrosio F, Barchowsky A. Arsenic Stimulates Myoblast Mitochondrial Epidermal Growth Factor Receptor to Impair Myogenesis. Toxicol Sci. 2020 07 01; 176(1):162-174. PMID: 32159786; PMCID: PMC7357174.
    Citations: 2     Fields:    Translation:AnimalsCells
  14. Willett NJ, Boninger ML, Miller LJ, Alvarez L, Aoyama T, Bedoni M, Brix KA, Chisari C, Christ G, Dearth CL, Dyson-Hudson TA, Evans CH, Goldman SM, Gregory K, Gualerzi A, Hart J, Ito A, Kuroki H, Loghmani MT, Mack DL, Malanga GA, Noble-Haeusslein L, Pasquina P, Roche JA, Rose L, Stoddart MJ, Tajino J, Terzic C, Topp KS, Wagner WR, Warden SJ, Wolf SL, Xie H, Rando TA, Ambrosio F. Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field. Arch Phys Med Rehabil. 2020 05; 101(5):917-923. PMID: 32035141; PMCID: PMC7576442.
    Citations: 10     Fields:    Translation:Humans
  15. Cheikhi A, Barchowsky A, Sahu A, Shinde SN, Pius A, Clemens ZJ, Li H, Kennedy CA, Hoeck JD, Franti M, Ambrosio F. Klotho: An Elephant in Aging Research. J Gerontol A Biol Sci Med Sci. 2019 06 18; 74(7):1031-1042. PMID: 30843026; PMCID: PMC7330474.
    Citations: 26     Fields:    Translation:HumansAnimals
  16. Cheikhi A, Wallace C, St Croix C, Cohen C, Tang WY, Wipf P, Benos PV, Ambrosio F, Barchowsky A. Mitochondria are a substrate of cellular memory. Free Radic Biol Med. 2019 01; 130:528-541. PMID: 30472365.
    Citations: 5     Fields:    Translation:AnimalsCells
  17. Ambrosio F, Rando TA. The regenerative rehabilitation collection: a forum for an emerging field. NPJ Regen Med. 2018; 3:20. PMID: 30374410; PMCID: PMC6195606.
    Citations: 3     
  18. Rando TA, Ambrosio F. Regenerative Rehabilitation: Applied Biophysics Meets Stem Cell Therapeutics. Cell Stem Cell. 2018 04 05; 22(4):608. PMID: 29625074.
    Citations: 5     Fields:    
  19. Rando TA, Ambrosio F. Regenerative Rehabilitation: Applied Biophysics Meets Stem Cell Therapeutics. Cell Stem Cell. 2018 03 01; 22(3):306-309. PMID: 29499150; PMCID: PMC5931336.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  20. Dalise S, Cavalli L, Ghuman H, Wahlberg B, Gerwig M, Chisari C, Ambrosio F, Modo M. Biological effects of dosing aerobic exercise and neuromuscular electrical stimulation in rats. Sci Rep. 2017 09 07; 7(1):10830. PMID: 28883534; PMCID: PMC5589775.
    Citations: 12     Fields:    Translation:Animals
  21. Moritz CT, Ambrosio F. Regenerative Rehabilitation: Combining Stem Cell Therapies and Activity-Dependent Stimulation. Pediatr Phys Ther. 2017 07; 29 Suppl 3:S10-S15. PMID: 28654473; PMCID: PMC5488706.
    Citations: 2     Fields:    Translation:Humans
  22. Lai S, Panarese A, Lawrence R, Boninger ML, Micera S, Ambrosio F. A Murine Model of Robotic Training to Evaluate Skeletal Muscle Recovery after Injury. Med Sci Sports Exerc. 2017 04; 49(4):840-847. PMID: 27875498.
    Citations: 1     Fields:    Translation:Animals
  23. Stearns-Reider KM, D'Amore A, Beezhold K, Rothrauff B, Cavalli L, Wagner WR, Vorp DA, Tsamis A, Shinde S, Zhang C, Barchowsky A, Rando TA, Tuan RS, Ambrosio F. Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion. Aging Cell. 2017 06; 16(3):518-528. PMID: 28371268; PMCID: PMC5418187.
    Citations: 75     Fields:    Translation:AnimalsCells
  24. Dziki J, Badylak S, Yabroudi M, Sicari B, Ambrosio F, Stearns K, Turner N, Wyse A, Boninger ML, Brown EHP, Rubin JP. An acellular biologic scaffold treatment for volumetric muscle loss: results of a 13-patient cohort study. NPJ Regen Med. 2016; 1:16008. PMID: 29302336; PMCID: PMC5744714.
    Citations: 62     
  25. Badylak SF, Dziki JL, Sicari BM, Ambrosio F, Boninger ML. Mechanisms by which acellular biologic scaffolds promote functional skeletal muscle restoration. Biomaterials. 2016 10; 103:128-136. PMID: 27376561.
    Citations: 22     Fields:    Translation:HumansCells
  26. Ambrosio F, Kleim JA. Regenerative Rehabilitation and Genomics: Frontiers in Clinical Practice. Phys Ther. 2016 Apr; 96(4):430-2. PMID: 27037291.
    Citations: 3     Fields:    Translation:Humans
  27. Ross HH, Ambrosio F, Trumbower RD, Reier PJ, Behrman AL, Wolf SL. Neural Stem Cell Therapy and Rehabilitation in the Central Nervous System: Emerging Partnerships. Phys Ther. 2016 May; 96(5):734-42. PMID: 26847015; PMCID: PMC6281018.
    Citations: 15     Fields:    Translation:HumansCells
  28. Zhang C, Ferrari R, Beezhold K, Stearns-Reider K, D'Amore A, Haschak M, Stolz D, Robbins PD, Barchowsky A, Ambrosio F. Arsenic Promotes NF-?b-Mediated Fibroblast Dysfunction and Matrix Remodeling to Impair Muscle Stem Cell Function. Stem Cells. 2016 Mar; 34(3):732-42. PMID: 26537186; PMCID: PMC4817845.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  29. Han N, Yabroudi MA, Stearns-Reider K, Helkowski W, Sicari BM, Rubin JP, Badylak SF, Boninger ML, Ambrosio F. Electrodiagnostic Evaluation of Individuals Implanted With Extracellular Matrix for the Treatment of Volumetric Muscle Injury: Case Series. Phys Ther. 2016 Apr; 96(4):540-9. PMID: 26564252; PMCID: PMC4817212.
    Citations: 13     Fields:    Translation:HumansCells
  30. Dalise S, Ambrosio F, Modo M. Brain plasticity and recovery in preclinical models of stroke. Arch Ital Biol. 2014 Dec; 152(4):190-215. PMID: 25987181.
    Citations: 7     Fields:    
  31. Gentile NE, Stearns KM, Brown EH, Rubin JP, Boninger ML, Dearth CL, Ambrosio F, Badylak SF. Targeted rehabilitation after extracellular matrix scaffold transplantation for the treatment of volumetric muscle loss. Am J Phys Med Rehabil. 2014 Nov; 93(11 Suppl 3):S79-87. PMID: 25133624.
    Citations: 19     Fields:    Translation:HumansCells
  32. Ambrosio F, Brown E, Stolz D, Ferrari R, Goodpaster B, Deasy B, Distefano G, Roperti A, Cheikhi A, Garciafigueroa Y, Barchowsky A. Arsenic induces sustained impairment of skeletal muscle and muscle progenitor cell ultrastructure and bioenergetics. Free Radic Biol Med. 2014 Sep; 74:64-73. PMID: 24960579; PMCID: PMC4159748.
    Citations: 20     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  33. Avin KG, Coen PM, Huang W, Stolz DB, Sowa GA, Dubé JJ, Goodpaster BH, O'Doherty RM, Ambrosio F. Skeletal muscle as a regulator of the longevity protein, Klotho. Front Physiol. 2014; 5:189. PMID: 24987372; PMCID: PMC4060456.
    Citations: 27     
  34. Sicari BM, Rubin JP, Dearth CL, Wolf MT, Ambrosio F, Boninger M, Turner NJ, Weber DJ, Simpson TW, Wyse A, Brown EH, Dziki JL, Fisher LE, Brown S, Badylak SF. An acellular biologic scaffold promotes skeletal muscle formation in mice and humans with volumetric muscle loss. Sci Transl Med. 2014 Apr 30; 6(234):234ra58. PMID: 24786326; PMCID: PMC5942588.
    Citations: 161     Fields:    Translation:HumansAnimalsCells
  35. Modo M, Ambrosio F, Friedlander RM, Badylak SF, Wechsler LR. Bioengineering solutions for neural repair and recovery in stroke. Curr Opin Neurol. 2013 Dec; 26(6):626-31. PMID: 24136127.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  36. Garciafigueroa DY, Klei LR, Ambrosio F, Barchowsky A. Arsenic-stimulated lipolysis and adipose remodeling is mediated by G-protein-coupled receptors. Toxicol Sci. 2013 Aug; 134(2):335-44. PMID: 23650128; PMCID: PMC3707436.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  37. Distefano G, Ferrari RJ, Weiss C, Deasy BM, Boninger ML, Fitzgerald GK, Huard J, Ambrosio F. Neuromuscular electrical stimulation as a method to maximize the beneficial effects of muscle stem cells transplanted into dystrophic skeletal muscle. PLoS One. 2013; 8(3):e54922. PMID: 23526927; PMCID: PMC3602431.
    Citations: 17     Fields:    Translation:AnimalsCells
  38. Ambrosio F, Boninger ML, Brubaker CE, Delitto A, Wagner WR, Shields RK, Wolf SL, Rando TA. Guest editorial: emergent themes from second annual symposium on regenerative rehabilitation, Pittsburgh, Pennsylvania. J Rehabil Res Dev. 2013; 50(3):vii-xiv. PMID: 23881770; PMCID: PMC4018824.
    Citations: 2     Fields:    Translation:HumansCells
  39. Kobayashi T, Uehara K, Ota S, Tobita K, Ambrosio F, Cummins JH, Terada S, Fu FH, Huard J. The timing of administration of a clinically relevant dose of losartan influences the healing process after contusion induced muscle injury. J Appl Physiol (1985). 2013 Jan 15; 114(2):262-73. PMID: 23154994; PMCID: PMC4074001.
    Citations: 17     Fields:    Translation:AnimalsCells
  40. Ambrosio F, Fitzgerald GK, Ferrari R, Distefano G, Carvell G. A murine model of muscle training by neuromuscular electrical stimulation. J Vis Exp. 2012 May 09; (63):e3914. PMID: 22617846; PMCID: PMC3468190.
    Citations: 9     Fields:    Translation:AnimalsCells
  41. Ambrosio F, Tarabishy A, Kadi F, Brown EH, Sowa G. Biological basis of exercise-based treatments for musculoskeletal conditions. PM R. 2011 Jun; 3(6 Suppl 1):S59-63. PMID: 21703582; PMCID: PMC4868068.
    Citations: 2     Fields:    Translation:Humans
  42. Markert CD, Ambrosio F, Call JA, Grange RW. Exercise and Duchenne muscular dystrophy: toward evidence-based exercise prescription. Muscle Nerve. 2011 Apr; 43(4):464-78. PMID: 21404285.
    Citations: 22     Fields:    Translation:HumansAnimals
  43. Ambrosio F, Wolf SL, Delitto A, Fitzgerald GK, Badylak SF, Boninger ML, Russell AJ. The emerging relationship between regenerative medicine and physical therapeutics. Phys Ther. 2010 Dec; 90(12):1807-14. PMID: 21030663; PMCID: PMC2996510.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  44. Ambrosio F, Ferrari RJ, Distefano G, Plassmeyer JM, Carvell GE, Deasy BM, Boninger ML, Fitzgerald GK, Huard J. The synergistic effect of treadmill running on stem-cell transplantation to heal injured skeletal muscle. Tissue Eng Part A. 2010 Mar; 16(3):839-49. PMID: 19788347; PMCID: PMC2862616.
    Citations: 31     Fields:    Translation:AnimalsCells
  45. Ambrosio F, Russell A. Regenerative rehabilitation: a call to action. J Rehabil Res Dev. 2010; 47(3):xi-xv. PMID: 20665343.
    Citations: 14     Fields:    Translation:Humans
  46. Deasy BM, Feduska JM, Payne TR, Li Y, Ambrosio F, Huard J. Effect of VEGF on the regenerative capacity of muscle stem cells in dystrophic skeletal muscle. Mol Ther. 2009 Oct; 17(10):1788-98. PMID: 19603004; PMCID: PMC2835014.
    Citations: 65     Fields:    Translation:AnimalsCells
  47. Markert CD, Atala A, Cann JK, Christ G, Furth M, Ambrosio F, Childers MK. Mesenchymal stem cells: emerging therapy for Duchenne muscular dystrophy. PM R. 2009 Jun; 1(6):547-59. PMID: 19627945; PMCID: PMC2746358.
    Citations: 14     Fields:    Translation:HumansAnimals
  48. Ambrosio F, Kadi F, Lexell J, Fitzgerald GK, Boninger ML, Huard J. The effect of muscle loading on skeletal muscle regenerative potential: an update of current research findings relating to aging and neuromuscular pathology. Am J Phys Med Rehabil. 2009 Feb; 88(2):145-55. PMID: 19169178; PMCID: PMC4872620.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  49. Ambrosio F, Ferrari RJ, Fitzgerald GK, Carvell G, Boninger ML, Huard J. Functional overloading of dystrophic mice enhances muscle-derived stem cell contribution to muscle contractile capacity. Arch Phys Med Rehabil. 2009 Jan; 90(1):66-73. PMID: 19154831; PMCID: PMC4878707.
    Citations: 8     Fields:    Translation:AnimalsCells
  50. Nozaki M, Li Y, Zhu J, Ambrosio F, Uehara K, Fu FH, Huard J. Improved muscle healing after contusion injury by the inhibitory effect of suramin on myostatin, a negative regulator of muscle growth. Am J Sports Med. 2008 Dec; 36(12):2354-62. PMID: 18725651.
    Citations: 38     Fields:    Translation:AnimalsCells
  51. Zhu J, Li Y, Shen W, Qiao C, Ambrosio F, Lavasani M, Nozaki M, Branca MF, Huard J. Relationships between transforming growth factor-beta1, myostatin, and decorin: implications for skeletal muscle fibrosis. J Biol Chem. 2007 Aug 31; 282(35):25852-63. PMID: 17597062.
    Citations: 114     Fields:    Translation:AnimalsCells
  52. Ambrosio F, Boninger ML, Fitzgerald SG, Hubbard SL, Schwid SR, Cooper RA. Comparison of mobility device delivery within Department of Veterans Affairs for individuals with multiple sclerosis versus spinal cord injury. J Rehabil Res Dev. 2007; 44(5):693-701. PMID: 17943681.
    Citations: 3     Fields:    Translation:Humans
  53. Souza AL, Boninger ML, Fitzgerald SG, Shimada SD, Cooper RA, Ambrosio F. Upper limb strength in individuals with spinal cord injury who use manual wheelchairs. J Spinal Cord Med. 2005; 28(1):26-32. PMID: 15832901.
    Citations: 6     Fields:    Translation:Humans
  54. Ambrosio F, Boninger ML, Souza AL, Fitzgerald SG, Koontz AM, Cooper RA. Biomechanics and strength of manual wheelchair users. J Spinal Cord Med. 2005; 28(5):407-14. PMID: 16869087; PMCID: PMC1808266.
    Citations: 19     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.