Harvard Catalyst Profiles

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Susana Vacas, M.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AG070269 (VACAS, SUSANA) Sep 11, 2020 - Aug 31, 2022
    Blood Brain Barrier Dysfunction and Perioperative Neurocognitive Disorders in older adults
    Role: Principal Investigator
  2. K23GM132795 (VACAS, SUSANA) Sep 20, 2019 - Aug 31, 2024
    Mechanisms Mediating Postoperative Neurocognitive Disorders
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Vacas S, Grogan T, Cheng D, Hofer I. Risk factor stratification for postoperative delirium: A retrospective database study. Medicine (Baltimore). 2022 Oct 21; 101(42):e31176. PMID: 36281117; PMCID: PMC9592358.
    Citations:    Fields:    Translation:Humans
  2. Pang B, Doshi S, Roy B, Lai M, Ehlert L, Aysola RS, Kang DW, Anderson A, Joshi SH, Tward D, Scalzo F, Vacas S, Kumar R. Machine learning approach for obstructive sleep apnea screening using brain diffusion tensor imaging. J Sleep Res. 2022 Oct 12; e13729. PMID: 36223645.
    Citations:    Fields:    
  3. Vacas S, Canales C, Deiner SG, Cole DJ. Perioperative Brain Health in the Older Adult: A Patient Safety Imperative. Anesth Analg. 2022 08 01; 135(2):316-328. PMID: 35584550.
    Citations:    Fields:    Translation:Humans
  4. Roy B, Nunez A, Aysola RS, Kang DW, Vacas S, Kumar R. Impaired Glymphatic System Actions in Obstructive Sleep Apnea Adults. Front Neurosci. 2022; 16:884234. PMID: 35600625.
  5. Song X, Roy B, Vacas S, Woo MA, Kang DW, Aysola RS, Kumar R. Brain regional homogeneity changes after short-term positive airway pressure treatment in patients with obstructive sleep apnea. Sleep Med. 2022 03; 91:12-20. PMID: 35245787.
    Citations: 2     Fields:    Translation:Humans
  6. Vacas S, Cole DJ, Cannesson M. Association of Cognitive Decline With Anesthesia and Surgery in Older Patients-Reply. JAMA. 2021 12 28; 326(24):2531. PMID: 34962534.
    Citations: 5     Fields:    Translation:Humans
  7. Roy B, Woo MS, Vacas S, Eshaghian P, Rao AP, Kumar R. Regional brain tissue changes in patients with cystic fibrosis. J Transl Med. 2021 10 09; 19(1):419. PMID: 34627274.
    Citations:    Fields:    Translation:Humans
  8. Vacas S, Cole DJ, Cannesson M. Cognitive Decline Associated With Anesthesia and Surgery in Older Patients. JAMA. 2021 Aug 02. PMID: 34338712; PMCID: PMC8807795.
    Citations: 2     Fields:    
  9. Lobo FA, Vacas S, Naranjo M. Loss of spectral alpha power during spine surgery: what could be wrong? J Clin Monit Comput. 2021 12; 35(6):1531-1533. PMID: 33991269.
    Citations: 2     Fields:    Translation:Humans
  10. Vlisides PE, Vogt KM, Pal D, Schnell E, Armstead WM, Brambrink AM, Kuo P, Nelson P, Vacas S, Goettel N, Aglio LS, Farag E, Gorji R, García PS, Koerner IP. Roadmap for Conducting Neuroscience Research in the COVID-19 Era and Beyond: Recommendations From the SNACC Research Committee. J Neurosurg Anesthesiol. 2021 Apr 01; 33(2):100-106. PMID: 33660699; PMCID: PMC8310904.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  11. Roy B, Vacas S, Ehlert L, McCloy K, Saggar R, Kumar R. Brain Structural Changes in Patients with Pulmonary Arterial Hypertension. J Neuroimaging. 2021 05; 31(3):524-531. PMID: 33565204.
    Citations:    Fields:    Translation:Humans
  12. Lobo FA, Vacas S, Rossetti AO, Robba C, Taccone FS. Does electroencephalographic burst suppression still play a role in the perioperative setting? Best Pract Res Clin Anaesthesiol. 2021 Jul; 35(2):159-169. PMID: 34030801.
    Citations: 3     Fields:    Translation:Humans
  13. Vandiver MS, Vacas S. Interventions to improve perioperative neurologic outcomes. Curr Opin Anaesthesiol. 2020 Oct; 33(5):661-667. PMID: 32769748.
    Citations:    Fields:    Translation:Humans
  14. Vacas S, Hudson AE. Seen and Ignored: Are We Undermining Studies of Brain Health Interventions Before We Start? Anesth Analg. 2020 08; 131(2):464-465. PMID: 32665496.
    Citations: 1     Fields:    Translation:Humans
  15. Joosten A, Rinehart J, Bardaji A, Van der Linden P, Jame V, Van Obbergh L, Alexander B, Cannesson M, Vacas S, Liu N, Slama H, Barvais L. Anesthetic Management Using Multiple Closed-loop Systems and Delayed Neurocognitive Recovery: A Randomized Controlled Trial. Anesthesiology. 2020 02; 132(2):253-266. PMID: 31939839.
    Citations: 12     Fields:    Translation:Humans
  16. Vacas S, Cannesson M. Noninvasive Monitoring and Potential for Patient Outcome. J Cardiothorac Vasc Anesth. 2019 08; 33 Suppl 1:S76-S83. PMID: 31279357; PMCID: PMC6783129.
    Citations: 2     Fields:    Translation:Humans
  17. Sleigh JW, Vacas S, Flexman AM, Talke PO. Electroencephalographic Arousal Patterns Under Dexmedetomidine Sedation. Anesth Analg. 2018 10; 127(4):951-959. PMID: 29933272.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  18. Yamada T, Vacas S, Gricourt Y, Cannesson M. Improving Perioperative Outcomes Through Minimally Invasive and Non-invasive Hemodynamic Monitoring Techniques. Front Med (Lausanne). 2018; 5:144. PMID: 29868596; PMCID: PMC5966660.
    Citations: 7     
  19. Hu J, Vacas S, Feng X, Lutrin D, Uchida Y, Lai IK, Maze M. Dexmedetomidine Prevents Cognitive Decline by Enhancing Resolution of High Mobility Group Box 1 Protein-induced Inflammation through a Vagomimetic Action in Mice. Anesthesiology. 2018 05; 128(5):921-931. PMID: 29252509.
    Citations: 24     Fields:    Translation:Animals
  20. Vacas S, Van de Wiele B. Designing a pain management protocol for craniotomy: A narrative review and consideration of promising practices. Surg Neurol Int. 2017; 8:291. PMID: 29285407.
    Citations: 13     
  21. Vacas S, Maze M. In Response. Anesth Analg. 2017 08; 125(2):695-696. PMID: 28661919.
    Citations:    Fields:    
  22. Vacas S, Degos V, Maze M. Fragmented Sleep Enhances Postoperative Neuroinflammation but Not Cognitive Dysfunction. Anesth Analg. 2017 01; 124(1):270-276. PMID: 27755058.
    Citations: 14     Fields:    Translation:Animals
  23. Vacas S, Maze M. Initiating Mechanisms of Surgery-induced Memory Decline: The Role of HMGB1. J Clin Cell Immunol. 2016 Dec; 7(6). PMID: 28674635.
    Citations: 3     
  24. Hirsch J, Vacas S, Terrando N, Yuan M, Sands LP, Kramer J, Bozic K, Maze MM, Leung JM. Perioperative cerebrospinal fluid and plasma inflammatory markers after orthopedic surgery. J Neuroinflammation. 2016 08 30; 13(1):211. PMID: 27577265; PMCID: PMC5006595.
    Citations: 61     Fields:    Translation:Humans
  25. Vacas S, McInrue E, Gropper MA, Maze M, Zak R, Lim E, Leung JM. The Feasibility and Utility of Continuous Sleep Monitoring in Critically Ill Patients Using a Portable Electroencephalography Monitor. Anesth Analg. 2016 07; 123(1):206-12. PMID: 27159066.
    Citations: 13     Fields:    Translation:Humans
  26. Gambús PL, Trocóniz IF, Feng X, Gimenez-Milá M, Mellado R, Degos V, Vacas S, Maze M. Relation between acute and long-term cognitive decline after surgery: Influence of metabolic syndrome. Brain Behav Immun. 2015 Nov; 50:203-208. PMID: 26164200.
    Citations: 6     Fields:    Translation:Animals
  27. Vacas S, Degos V, Maze M. In reply. Anesthesiology. 2014 Dec; 121(6):1353-4. PMID: 25405302.
    Citations:    Fields:    Translation:AnimalsCells
  28. Flexman AM, Wong H, Riggs KW, Shih T, Garcia PA, Vacas S, Talke PO. Enzyme-inducing anticonvulsants increase plasma clearance of dexmedetomidine: a pharmacokinetic and pharmacodynamic study. Anesthesiology. 2014 May; 120(5):1118-25. PMID: 24487703.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  29. Vacas S, Degos V, Tracey KJ, Maze M. High-mobility group box 1 protein initiates postoperative cognitive decline by engaging bone marrow-derived macrophages. Anesthesiology. 2014 May; 120(5):1160-7. PMID: 24162463; PMCID: PMC3999217.
    Citations: 63     Fields:    Translation:AnimalsCells
  30. Degos V, Maze M, Vacas S, Hirsch J, Guo Y, Shen F, Jun K, van Rooijen N, Gressens P, Young WL, Su H. Bone fracture exacerbates murine ischemic cerebral injury. Anesthesiology. 2013 Jun; 118(6):1362-72. PMID: 23438676; PMCID: PMC3987811.
    Citations: 24     Fields:    Translation:AnimalsCells
  31. Feng X, Degos V, Koch LG, Britton SL, Zhu Y, Vacas S, Terrando N, Nelson J, Su X, Maze M. Surgery results in exaggerated and persistent cognitive decline in a rat model of the Metabolic Syndrome. Anesthesiology. 2013 May; 118(5):1098-105. PMID: 23353794; PMCID: PMC5530762.
    Citations: 38     Fields:    Translation:Animals
  32. Vacas S, Degos V, Feng X, Maze M. The neuroinflammatory response of postoperative cognitive decline. Br Med Bull. 2013; 106:161-78. PMID: 23558082.
    Citations: 71     Fields:    Translation:Humans
  33. Vacas S, Kurien P, Maze M. Sleep and Anesthesia - Common mechanisms of action. Sleep Med Clin. 2013 Mar; 8(1):1-9. PMID: 28747855.
    Citations: 7     Fields:    
  34. Degos V, Vacas S, Han Z, van Rooijen N, Gressens P, Su H, Young WL, Maze M. Depletion of bone marrow-derived macrophages perturbs the innate immune response to surgery and reduces postoperative memory dysfunction. Anesthesiology. 2013 Mar; 118(3):527-36. PMID: 23426204; PMCID: PMC3779063.
    Citations: 63     Fields:    Translation:AnimalsCells
  35. Terrando N, Brzezinski M, Degos V, Eriksson LI, Kramer JH, Leung JM, Miller BL, Seeley WW, Vacas S, Weiner MW, Yaffe K, Young WL, Xie Z, Maze M. Perioperative cognitive decline in the aging population. Mayo Clin Proc. 2011 Sep; 86(9):885-93. PMID: 21878601; PMCID: PMC3257991.
    Citations: 72     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.