Harvard Catalyst Profiles

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Ahmed Al Saedi, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Alfonzo MC, Al Saedi A, Fulzele S, Hamrick MW. Extracellular Vesicles as Communicators of Senescence in Musculoskeletal Aging. JBMR Plus. 2022 Nov; 6(11):e10686. PMID: 36398109; PMCID: PMC9664547.
    Citations: 1     
  2. Al Saedi A, Debruin DA, Hayes A, Hamrick M. Lipid metabolism in sarcopenia. Bone. 2022 11; 164:116539. PMID: 36007811.
    Citations: 2     Fields:    Translation:Humans
  3. Al Saedi A, Wang Z, Shah A, Brotto M, Duque G. Comparative analysis of fat composition in marrow, serum, and muscle from aging C57BL6 mice. Mech Ageing Dev. 2022 09; 206:111690. PMID: 35752298.
    Citations:    Fields:    Translation:Animals
  4. Al Saedi A, Kirk B, Iuliano S, Zanker J, Vogrin S, Jayaram L, Thomas S, Golding C, Navarro-Perez D, Marusic P, Leng S, Nanan R, Duque G. Effects of 3 months of multi-nutrient supplementation on the immune system and muscle and respiratory function of older adults in aged care (The Pomerium Study): protocol for a randomised controlled trial. BMJ Open. 2022 05 06; 12(5):e059075. PMID: 35523505; PMCID: PMC9082724.
    Citations:    Fields:    Translation:HumansCellsCTClinical Trials
  5. Al Saedi A, Sharma S, Bani Hassan E, Chen L, Ghasem-Zadeh A, Hassanzadeganroudsari M, Gooi JH, Stavely R, Eri R, Miao D, Nurgali K, Duque G. Characterization of Skeletal Phenotype and Associated Mechanisms With Chronic Intestinal Inflammation in the Winnie Mouse Model of Spontaneous Chronic Colitis. Inflamm Bowel Dis. 2022 02 01; 28(2):259-272. PMID: 34347076.
    Citations:    Fields:    Translation:HumansAnimals
  6. Al Saedi A, Chow S, Vogrin S, Guillemin GJ, Duque G. Association Between Tryptophan Metabolites, Physical Performance, and Frailty in Older Persons. Int J Tryptophan Res. 2022; 15:11786469211069951. PMID: 35125874; PMCID: PMC8808031.
  7. Al Saedi A, Phu S, Vogrin S, Gunawardene P, Duque G. Association between Circulating Osteoprogenitor Cells and Sarcopenia. Gerontology. 2022; 68(9):1038-1043. PMID: 34856541.
    Citations: 3     Fields:    Translation:Humans
  8. Feehan J, Smith C, Tripodi N, Degabrielle E, Al Saedi A, Vogrin S, Duque G, Levinger I. Higher Levels of Circulating Osteoprogenitor Cells Are Associated With Higher Bone Mineral Density and Lean Mass in Older Adults: A Cross-Sectional Study. JBMR Plus. 2021 Nov; 5(11):e10561. PMID: 34761152; PMCID: PMC8567483.
    Citations: 2     
  9. Feehan J, Degabrielle E, Tripodi N, Al Saedi A, Vogrin S, Duque G. The effect of vitamin D supplementation on circulating osteoprogenitor cells: A pilot randomized controlled trial. Exp Gerontol. 2021 07 15; 150:111399. PMID: 33971278.
    Citations: 2     Fields:    Translation:Humans
  10. Al Saedi A, Duque G, Stupka N. Targeting intramuscular adipose tissue expansion to preserve contractile function in volumetric muscle loss: A potentially novel therapy? Curr Opin Pharmacol. 2021 06; 58:21-26. PMID: 33848932.
    Citations:    Fields:    Translation:HumansAnimals
  11. Smith C, Lin X, Scott D, Brennan-Speranza TC, Al Saedi A, Moreno-Asso A, Woessner M, Bani Hassan E, Eynon N, Duque G, Levinger I. Uncovering the Bone-Muscle Interaction and Its Implications for the Health and Function of Older Adults (the Wellderly Project): Protocol for a Randomized Controlled Crossover Trial. JMIR Res Protoc. 2021 Apr 09; 10(4):e18777. PMID: 33835038; PMCID: PMC8065561.
    Citations: 4     
  12. Duque G, Al Saedi A, Rivas D, Miard S, Ferland G, Picard F, Gaudreau P. Differential Effects of Long-Term Caloric Restriction and Dietary Protein Source on Bone and Marrow Fat of the Aging Rat. J Gerontol A Biol Sci Med Sci. 2020 10 15; 75(11):2031-2036. PMID: 32298404; PMCID: PMC7566446.
    Citations: 3     Fields:    Translation:AnimalsCells
  13. Al Saedi A, Myers DE, Stupka N, Duque G. 1,25(OH)2D3 ameliorates palmitate-induced lipotoxicity in human primary osteoblasts leading to improved viability and function. Bone. 2020 12; 141:115672. PMID: 33011427.
    Citations: 7     Fields:    Translation:HumansCells
  14. Duque G, Vidal C, Li W, Al Saedi A, Khalil M, Lim CK, Myers DE, Guillemin GJ. Picolinic Acid, a Catabolite of Tryptophan, Has an Anabolic Effect on Bone In Vivo. J Bone Miner Res. 2020 11; 35(11):2275-2288. PMID: 32629550.
    Citations: 5     Fields:    Translation:AnimalsCells
  15. Al Saedi A, Chen L, Phu S, Vogrin S, Miao D, Ferland G, Gaudreau P, Duque G. Age-Related Increases in Marrow Fat Volumes have Regional Impacts on Bone Cell Numbers and Structure. Calcif Tissue Int. 2020 08; 107(2):126-134. PMID: 32356017.
    Citations: 1     Fields:    Translation:AnimalsCells
  16. Al Saedi A, A Goodman C, E Myers D, Hayes A, Duque G. Rapamycin Affects Palmitate-Induced Lipotoxicity in Osteoblasts by Modulating Apoptosis and Autophagy. J Gerontol A Biol Sci Med Sci. 2020 01 01; 75(1):58-63. PMID: 31241126.
    Citations: 9     Fields:    Translation:HumansCells
  17. Al Saedi A, Stupka N, Duque G. Pathogenesis of Osteoporosis. Handb Exp Pharmacol. 2020; 262:353-367. PMID: 32297003.
    Citations: 1     Fields:    Translation:HumansCells
  18. Feehan J, Al Saedi A, Duque G. Targeting fundamental aging mechanisms to treat osteoporosis. Expert Opin Ther Targets. 2019 12; 23(12):1031-1039. PMID: 31815563.
    Citations: 4     Fields:    Translation:HumansAnimals
  19. Al Saedi A, Sharma S, Summers MA, Nurgali K, Duque G. The multiple faces of tryptophan in bone biology. Exp Gerontol. 2020 01; 129:110778. PMID: 31705966.
    Citations: 11     Fields:    Translation:HumansCells
  20. SepĂșlveda-Loyola W, Phu S, Bani Hassan E, Brennan-Olsen SL, Zanker J, Vogrin S, Conzade R, Kirk B, Al Saedi A, Probst V, Duque G. The Joint Occurrence of Osteoporosis and Sarcopenia (Osteosarcopenia): Definitions and Characteristics. J Am Med Dir Assoc. 2020 02; 21(2):220-225. PMID: 31669290.
    Citations: 28     Fields:    Translation:Humans
  21. Smith C, Voisin S, Al Saedi A, Phu S, Brennan-Speranza T, Parker L, Eynon N, Hiam D, Yan X, Scott D, Blekkenhorst LC, Lewis JR, Seeman E, Byrnes E, Flicker L, Duque G, Yeap BB, Levinger I. Osteocalcin and its forms across the lifespan in adult men. Bone. 2020 01; 130:115085. PMID: 31622778.
    Citations: 8     Fields:    Translation:Humans
  22. Kirk B, Al Saedi A, Duque G. Osteosarcopenia: A case of geroscience. Aging Med (Milton). 2019 Sep; 2(3):147-156. PMID: 31942528; PMCID: PMC6880711.
    Citations: 25     
  23. Phu S, Vogrin S, Al Saedi A, Duque G. Balance training using virtual reality improves balance and physical performance in older adults at high risk of falls. Clin Interv Aging. 2019; 14:1567-1577. PMID: 31695345; PMCID: PMC6717859.
    Citations: 14     Fields:    Translation:Humans
  24. Al Saedi A, Bermeo S, Plotkin L, Myers DE, Duque G. Mechanisms of palmitate-induced lipotoxicity in osteocytes. Bone. 2019 10; 127:353-359. PMID: 31226530.
    Citations: 8     Fields:    Translation:AnimalsCells
  25. Bermeo S, Al Saedi A, Vidal C, Khalil M, Pang M, Troen BR, Myers D, Duque G. Treatment with an inhibitor of fatty acid synthase attenuates bone loss in ovariectomized mice. Bone. 2019 05; 122:114-122. PMID: 30779961.
    Citations: 8     Fields:    Translation:AnimalsCells
  26. Phu S, Vogrin S, Zanker J, Bani Hassan E, Al Saedi A, Duque G. Agreement Between Initial and Revised European Working Group on Sarcopenia in Older People Definitions. J Am Med Dir Assoc. 2019 03; 20(3):382-383.e1. PMID: 30661862.
    Citations: 18     Fields:    Translation:Humans
  27. Feehan J, Nurgali K, Apostolopoulos V, Al Saedi A, Duque G. Circulating osteogenic precursor cells: Building bone from blood. EBioMedicine. 2019 Jan; 39:603-611. PMID: 30522933; PMCID: PMC6354620.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  28. Hsu PS, Lai CL, Hu M, Santner-Nanan B, Dahlstrom JE, Lee CH, Ajmal A, Bullman A, Arbuckle S, Al Saedi A, Gacis L, Nambiar R, Williams A, Wong M, Campbell DE, Nanan R. IL-2 Enhances Gut Homing Potential of Human Naive Regulatory T Cells Early in Life. J Immunol. 2018 06 15; 200(12):3970-3980. PMID: 29720424.
    Citations: 4     Fields:    Translation:HumansCells
  29. Al Saedi A, Gunawardene P, Bermeo S, Vogrin S, Boersma D, Phu S, Singh L, Suriyaarachchi P, Duque G. Lamin A expression in circulating osteoprogenitors as a potential biomarker for frailty: The Nepean Osteoporosis and Frailty (NOF) Study. Exp Gerontol. 2018 02; 102:69-75. PMID: 29203402.
    Citations: 8     Fields:    Translation:HumansCells
  30. Gunawardene P, Al Saedi A, Singh L, Bermeo S, Vogrin S, Phu S, Suriyaarachchi P, Pignolo RJ, Duque G. Age, gender, and percentage of circulating osteoprogenitor (COP) cells: The COP Study. Exp Gerontol. 2017 10 01; 96:68-72. PMID: 28599951.
    Citations: 14     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.