Harvard Catalyst Profiles

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Torsten Oliver Steinbrunn, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Solimando AG, Da Vià MC, Bolli N, Steinbrunn T. The Route of the Malignant Plasma Cell in Its Survival Niche: Exploring "Multiple Myelomas". Cancers (Basel). 2022 Jul 04; 14(13). PMID: 35805041; PMCID: PMC9265748.
    Citations: 2     
  2. Solimando AG, Da Vià MC, Leone P, Borrelli P, Croci GA, Tabares P, Brandl A, Di Lernia G, Bianchi FP, Tafuri S, Steinbrunn T, Balduini A, Melaccio A, De Summa S, Argentiero A, Rauert-Wunderlich H, Frassanito MA, Ditonno P, Henke E, Klapper W, Ria R, Terragna C, Rasche L, Rosenwald A, Kortüm MK, Cavo M, Ribatti D, Racanelli V, Einsele H, Vacca A, Beilhack A. Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores angiogenic homeostasis and suppresses tumor progression. Haematologica. 2021 07 01; 106(7):1943-1956. PMID: 32354870; PMCID: PMC8252928.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  3. Kraus S, Dierks A, Rasche L, Kertels O, Kircher M, Schirbel A, Zovko J, Steinbrunn T, Tibes R, Wester HJ, Buck AK, Einsele H, Kortüm KM, Rosenwald A, Lapa C. 68Ga-Pentixafor PET/CT for Detection of Chemokine Receptor CXCR4 Expression in Myeloproliferative Neoplasms. J Nucl Med. 2022 01; 63(1):96-99. PMID: 34049979; PMCID: PMC8717205.
    Citations: 3     Fields:    
  4. Leich E, Schreder M, Pischimarov J, Stühmer T, Steinbrunn T, Rudelius M, Brünnert D, Chatterjee M, Langer C, Keppler S, Heredia-Guerrero SC, Einsele H, Knop S, Bargou RC, Rosenwald A. Novel molecular subgroups within the context of receptor tyrosine kinase and adhesion signalling in multiple myeloma. Blood Cancer J. 2021 03 04; 11(3):51. PMID: 33664224; PMCID: PMC7933144.
    Citations:    Fields:    Translation:HumansCells
  5. Steinbrunn T, Zovko J, Kraus S. JAK Inhibitors for the Treatment of Hemato-Oncological Diseases. Akt. Rheumatol. 2020; 45(6):559-567. View Publication.
  6. Seibold M, Stühmer T, Kremer N, Mottok A, Scholz CJ, Schlosser A, Leich E, Holzgrabe U, Brünnert D, Barrio S, Kortüm MK, Solimando AG, Chatterjee M, Einsele H, Rosenwald A, Bargou RC, Steinbrunn T. RAL GTPases mediate multiple myeloma cell survival and are activated independently of oncogenic RAS. Haematologica. 2020 09 01; 105(9):2316-2326. PMID: 33054056; PMCID: PMC7556628.
    Citations: 7     Fields:    Translation:Humans
  7. Steinbrunn T, Knop S, Einsele H. Multiple Myeloma - Dynamic Developments Regarding Disease Understanding and Therapy. Die Onkologie. 2020; 26:661-672. View Publication.
  8. Weißbach S, Heredia-Guerrero SC, Barnsteiner S, Großhans L, Bodem J, Starz H, Langer C, Appenzeller S, Knop S, Steinbrunn T, Rost S, Einsele H, Bargou RC, Rosenwald A, Stühmer T, Leich E. Exon-4 Mutations in KRAS Affect MEK/ERK and PI3K/AKT Signaling in Human Multiple Myeloma Cell Lines. Cancers (Basel). 2020 Feb 16; 12(2). PMID: 32079091; PMCID: PMC7072554.
    Citations: 3     
  9. Barrio S, Munawar U, Zhu YX, Giesen N, Shi CX, Viá MD, Sanchez R, Bruins L, Demler T, Müller N, Haertle L, Garitano A, Steinbrunn T, Danhof S, Cuenca I, Barrio-Garcia C, Braggio E, Rosenwald A, Martinez-Lopez J, Rasche L, Raab MS, Stewart AK, Einsele H, Stühmer T, Kortüm KM. IKZF1/3 and CRL4CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma. Haematologica. 2020 05; 105(5):e237-e241. PMID: 31558666; PMCID: PMC7193510.
    Citations: 22     Fields:    Translation:Humans
  10. Barrio S, DáVia M, Bruins L, Stühmer T, Steinbrunn T, Bittrich M, Einsele H, Stewart AK, Braggio E, Kortüm KM. Protocol for M3P: A Comprehensive and Clinical Oriented Targeted Sequencing Panel for Routine Molecular Analysis in Multiple Myeloma. Methods Mol Biol. 2018; 1792:117-128. PMID: 29797255.
    Citations: 4     Fields:    Translation:Humans
  11. Müller E, Bauer S, Stühmer T, Mottok A, Scholz CJ, Steinbrunn T, Brünnert D, Brandl A, Schraud H, Kreßmann S, Beilhack A, Rosenwald A, Bargou RC, Chatterjee M. Pan-Raf co-operates with PI3K-dependent signalling and critically contributes to myeloma cell survival independently of mutated RAS. Leukemia. 2017 Apr; 31(4):922-933. PMID: 27686868.
    Citations:    
  12. Keppler S, Weißbach S, Langer C, Knop S, Pischimarov J, Kull M, Stühmer T, Steinbrunn T, Bargou R, Einsele H, Rosenwald A, Leich E. Rare SNPs in receptor tyrosine kinases are negative outcome predictors in multiple myeloma. Oncotarget. 2016 Jun 21; 7(25):38762-38774. PMID: 27246973; PMCID: PMC5122427.
    Citations: 3     Fields:    Translation:HumansCells
  13. Rasche L, Menoret E, Dubljevic V, Menu E, Vanderkerken K, Lapa C, Steinbrunn T, Chatterjee M, Knop S, Düll J, Greenwood DL, Hensel F, Rosenwald A, Einsele H, Brändlein S. A GRP78-Directed Monoclonal Antibody Recaptures Response in Refractory Multiple Myeloma with Extramedullary Involvement. Clin Cancer Res. 2016 Sep 01; 22(17):4341-9. PMID: 27029491.
    Citations: 14     Fields:    Translation:HumansCells
  14. Leich E, Steinbrunn T. RAS mutations - for better or for worse in multiple myeloma? Leuk Lymphoma. 2016; 57(1):8-9. PMID: 26430811.
    Citations: 2     Fields:    Translation:Humans
  15. Steinbrunn T, Chatterjee M, Bargou RC, Stühmer T. Efficient transient transfection of human multiple myeloma cells by electroporation--an appraisal. PLoS One. 2014; 9(6):e97443. PMID: 24901949; PMCID: PMC4047019.
    Citations: 11     Fields:    Translation:HumansCells
  16. Hofmann C, Stühmer T, Schmiedl N, Wetzker R, Mottok A, Rosenwald A, Langer C, Zovko J, Chatterjee M, Einsele H, Bargou RC, Steinbrunn T. PI3K-dependent multiple myeloma cell survival is mediated by the PIK3CA isoform. Br J Haematol. 2014 Aug; 166(4):529-39. PMID: 24766330.
    Citations: 8     Fields:    Translation:HumansCells
  17. Leich E, Weißbach S, Klein HU, Grieb T, Pischimarov J, Stühmer T, Chatterjee M, Steinbrunn T, Langer C, Eilers M, Knop S, Einsele H, Bargou R, Rosenwald AMultiple myeloma is affected by multiple and heterogeneous somatic mutations in adhesion- and receptor tyrosine kinase signaling molecules. Blood Cancer J. 2013 Feb 08; 3:e102. PMID: 23396385.
    Citations: 28     Fields:    
  18. Chatterjee M, Andrulis M, Stühmer T, Müller E, Hofmann C, Steinbrunn T, Heimberger T, Schraud H, Kressmann S, Einsele H, Bargou RC. The PI3K/Akt signaling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma. Haematologica. 2013 Jul; 98(7):1132-41. PMID: 23065523; PMCID: PMC3696618.
    Citations: 60     Fields:    Translation:HumansCells
  19. Steinbrunn T, Stühmer T, Sayehli C, Chatterjee M, Einsele H, Bargou RC. Combined targeting of MEK/MAPK and PI3K/Akt signalling in multiple myeloma. Br J Haematol. 2012 Nov; 159(4):430-40. PMID: 22985491.
    Citations: 19     Fields:    Translation:HumansCells
  20. Steinbrunn T, Siegmund D, Andrulis M, Grella E, Kortüm M, Einsele H, Wajant H, Bargou RC, Stühmer T. Integrin-linked kinase is dispensable for multiple myeloma cell survival. Leuk Res. 2012 Sep; 36(9):1165-71. PMID: 22658851.
    Citations: 9     Fields:    Translation:HumansCells
  21. Steinbrunn T, Stühmer T, Gattenlöhner S, Rosenwald A, Mottok A, Unzicker C, Einsele H, Chatterjee M, Bargou RC. Mutated RAS and constitutively activated Akt delineate distinct oncogenic pathways, which independently contribute to multiple myeloma cell survival. Blood. 2011 Feb 10; 117(6):1998-2004. PMID: 21149634.
    Citations: 38     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.