Harvard Catalyst Profiles

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Eric Peter Schmidt, M.D.

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Biography
education and training
Dartmouth College, Hanover, NHBA06/1997Government
University of Pittsburgh, Pittsburgh, PAMD06/2001Medicine
Johns Hopkins Hospital, Baltimore, MD06/2004Internal Medicine Residency
Johns Hopkins Hospital, Baltimore, MD06/2006Assistant Chief of Service
Johns Hopkins Hospital, Baltimore, MD06/2009Pulmonary/Critical Care Fellowship
awards and honors
2001
Mayer A. Green Award in Internal Medicine
2001
Medical Alumni Association Recognition Award
2013
American Physiological Society Giles F. Filley Memorial Award
2013
University of Colorado Outstanding Early Career Scholar
2014
Denver Health Academic Excellence Award
2015
ATS Early Career Research Achievement Award
2019
Fellow of the American Thoracic Society
2023
American Society for Clinical Investigation
2024
Andrew M. Tager, MD Endowed Chair of Pulmonary and Critical Care Medicine
2025
Fellow of the American Physiological Society

Overview
overview
Our laboratory focuses on the mechanisms underlying sepsis and septic organ injury. We are particularly interested in the role of glycosaminoglycans (such as heparan sulfate) in the onset, propagation, and resolution of septic lung, kidney, and brain injury. Using novel glycoanalytical approaches, we seek to find new insights into the mechanistic and phenotypic heterogeneity of critical illness.
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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R21GM151565 (SCHMIDT, ERIC PETER) Jul 14, 2023 - Aug 31, 2025
    NIH
    Optimization of a rapid assay to quantify circulating glycosaminoglycans and identify vascular endotypes of sepsis.
    Role Description: The goal of this study is to test the accuracy of dimethylmethylene blue (DMMB) as a rapid, point-of-care assay of endothelial glycocalyx degradation, and then use this optimized assay to discern vascular endotypes of sepsis and septic shock.
    Role: Principal Investigator
  2. R21GM151565 (SCHMIDT, ERIC PETER) Jul 14, 2023 - Jun 30, 2025
    NIH
    Optimization of a rapid assay to quantify circulating glycosaminoglycans and identify vascular endotypes of sepsis
    Role: Principal Investigator
  3. R01HL168892 (HERSON, PACO S) Mar 15, 2023 - Feb 29, 2028
    NIH
    Vascular mechanisms of sepsis-induced cognitive dysfunction
    Role: Co-Principal Investigator
  4. R01HL168892-01 (HERSON, PACO S) Mar 15, 2023 - Feb 29, 2028
    NIH
    Vascular mechanisms of sepsis-induced cognitive dysfunction
    Role Description: The goal of this study is to understand the mechanisms by which circulating heparan sulfates selectively penetrate memory centers of the brain, leading to cognitive impairment in sepsis survivors.
    Role: Co-Principal Investigator
  5. R13HL152479 (SCHMIDT, ERIC PETER) Jul 1, 2020 - Jun 30, 2021
    NIH
    ARDS in the 21st Century: New Insights into Clinical and Mechanistic Heterogeneity
    Role: Principal Investigator

Bibliographic
selected publications
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© 2025 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.