Harvard Catalyst Profiles

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Daniel Ardeljan, M.D., Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Antiochos B, Paz M, Li J, Goldman DW, Petri M, Darrah E, Cashman K, Sanz I, Burns KH, Ardeljan D, Andrade F, Rosen A. Autoantibodies targeting LINE-1-encoded ORF1p are associated with systemic lupus erythematosus diagnosis but not disease activity. Clin Exp Rheumatol. 2022 Sep; 40(9):1636-1641. PMID: 34665712.
    Citations: 1     Fields:    
  2. Ardeljan D, Steranka JP, Liu C, Li Z, Taylor MS, Payer LM, Gorbounov M, Sarnecki JS, Deshpande V, Hruban RH, Boeke JD, Fenyö D, Wu PH, Smogorzewska A, Holland AJ, Burns KH. Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication. Nat Struct Mol Biol. 2020 02; 27(2):168-178. PMID: 32042151; PMCID: PMC7080318.
    Citations: 24     Fields:    Translation:HumansCells
  3. Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F, Demeulemeester J, Santamarina M, Ju YS, Temes J, Garcia-Souto D, Detering H, Li Y, Rodriguez-Castro J, Dueso-Barroso A, Bruzos AL, Dentro SC, Blanco MG, Contino G, Ardeljan D, Tojo M, Roberts ND, Zumalave S, Edwards PAW, Weischenfeldt J, Puiggròs M, Chong Z, Chen K, Lee EA, Wala JA, Raine K, Butler A, Waszak SM, Navarro FCP, Schumacher SE, Monlong J, Maura F, Bolli N, Bourque G, Gerstein M, Park PJ, Wedge DC, Beroukhim R, Torrents D, Korbel JO, Martincorena I, Fitzgerald RC, Van Loo P, Kazazian HH, Burns KH, Campbell PJ, Tubio JMC. Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition. Nat Genet. 2020 03; 52(3):306-319. PMID: 32024998; PMCID: PMC7058536.
    Citations: 84     Fields:    Translation:HumansCells
  4. Ardeljan D, Wang X, Oghbaie M, Taylor MS, Husband D, Deshpande V, Steranka JP, Gorbounov M, Yang WR, Sie B, Larman HB, Jiang H, Molloy KR, Altukhov I, Li Z, McKerrow W, Fenyö D, Burns KH, LaCava J. LINE-1 ORF2p expression is nearly imperceptible in human cancers. Mob DNA. 2020; 11:1. PMID: 31892958; PMCID: PMC6937734.
    Citations: 14     
  5. Yang WR, Ardeljan D, Pacyna CN, Payer LM, Burns KH. SQuIRE reveals locus-specific regulation of interspersed repeat expression. Nucleic Acids Res. 2019 03 18; 47(5):e27. PMID: 30624635; PMCID: PMC6411935.
    Citations: 34     Fields:    Translation:AnimalsCells
  6. Payer LM, Steranka JP, Ardeljan D, Walker J, Fitzgerald KC, Calabresi PA, Cooper TA, Burns KH. Alu insertion variants alter mRNA splicing. Nucleic Acids Res. 2019 01 10; 47(1):421-431. PMID: 30418605.
    Citations: 27     Fields:    Translation:HumansCells
  7. Payer LM, Steranka JP, Yang WR, Kryatova M, Medabalimi S, Ardeljan D, Liu C, Boeke JD, Avramopoulos D, Burns KH. Structural variants caused by Alu insertions are associated with risks for many human diseases. Proc Natl Acad Sci U S A. 2017 05 16; 114(20):E3984-E3992. PMID: 28465436; PMCID: PMC5441760.
    Citations: 53     Fields:    Translation:HumansCells
  8. Ardeljan D, Taylor MS, Ting DT, Burns KH. The Human Long Interspersed Element-1 Retrotransposon: An Emerging Biomarker of Neoplasia. Clin Chem. 2017 04; 63(4):816-822. PMID: 28188229; PMCID: PMC6177209.
    Citations: 39     Fields:    Translation:HumansCells
  9. Ardeljan D, Taylor MS, Burns KH, Boeke JD, Espey MG, Woodhouse EC, Howcroft TK. Meeting Report: The Role of the Mobilome in Cancer. Cancer Res. 2016 08 01; 76(15):4316-9. PMID: 27527733; PMCID: PMC4991632.
    Citations: 3     Fields:    Translation:HumansCells
  10. Ardeljan D, Wang Y, Park S, Shen D, Chu XK, Yu CR, Abu-Asab M, Tuo J, Eberhart CG, Olsen TW, Mullins RF, White G, Wadsworth S, Scaria A, Chan CC. Interleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration. PLoS One. 2014; 9(4):e95900. PMID: 24780906; PMCID: PMC4004582.
    Citations: 28     Fields:    Translation:HumansCells
  11. Ardeljan CP, Ardeljan D, Abu-Asab M, Chan CC. Inflammation and Cell Death in Age-Related Macular Degeneration: An Immunopathological and Ultrastructural Model. J Clin Med. 2014; 3(4):1542-60. PMID: 25580276; PMCID: PMC4287551.
    Citations: 24     
  12. Chan CC, Ardeljan D. Molecular pathology of macrophages and interleukin-17 in age-related macular degeneration. Adv Exp Med Biol. 2014; 801:193-8. PMID: 24664698; PMCID: PMC4153378.
    Citations: 15     Fields:    Translation:HumansCells
  13. Ardeljan D, Chan CC. Aging is not a disease: distinguishing age-related macular degeneration from aging. Prog Retin Eye Res. 2013 Nov; 37:68-89. PMID: 23933169; PMCID: PMC3830684.
    Citations: 97     Fields:    Translation:Humans
  14. Ardeljan D, Meyerle CB, Agron E, Wang JJ, Mitchell P, Chew EY, Zhao J, Maminishkis A, Chan CC, Tuo J. Influence of TIMP3/SYN3 polymorphisms on the phenotypic presentation of age-related macular degeneration. Eur J Hum Genet. 2013 Oct; 21(10):1152-7. PMID: 23422939; PMCID: PMC3778351.
    Citations: 15     Fields:    Translation:HumansCells
  15. Chan CC, Ardeljan D. Ten Chairpersons of the Ophthalmology Department at Peking Union Medical College. Asia Pac J Ophthalmol (Phila). 2013 Jan-Feb; 2(1):3-8. PMID: 26107860.
    Citations:    Fields:    
  16. Chu XK, Wang Y, Ardeljan D, Tuo J, Chan CC. Controversial view of a genetically altered mouse model of focal retinal degeneration. Bioengineered. 2013 May-Jun; 4(3):130-5. PMID: 23196746; PMCID: PMC3669152.
    Citations: 20     Fields:    Translation:HumansAnimals
  17. Wang VM, Rosen RB, Meyerle CB, Kurup SK, Ardeljan D, Agron E, Tai K, Pomykala M, Chew EY, Chan CC, Tuo J. Suggestive association between PLA2G12A single nucleotide polymorphism rs2285714 and response to anti-vascular endothelial growth factor therapy in patients with exudative age-related macular degeneration. Mol Vis. 2012; 18:2578-85. PMID: 23112570; PMCID: PMC3482167.
    Citations: 11     Fields:    Translation:Humans
  18. Ardeljan D, Tuo J, Chan CC. Carboxyethylpyrrole plasma biomarkers in age-related macular degeneration. Drugs Future. 2011 Sep 01; 36(9):712-718. PMID: 23847393; PMCID: PMC3705766.
    Citations: 4     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.