Harvard Catalyst Profiles

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Christian Guay, M.D.

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Massachusetts General Hospital, Boston, MA06/2024Fellowship - Cardiothoracic Anesthesiology
Massachusetts General Hospital, Boston, MA06/2023Fellowship - Critical Care Medicine
Washington University School of Medicine, St. Louis06/2022Residency - Anesthesiology
Peter E. Krucylak Award (Washington University School of Medicine)
Margaret Wood Resident Research Award (Association of University Anesthesiologists)
Kosaka Best Abstract Award Finalist (International Anesthesia Research Society)
Alpha Omega Alpha Honor Medical Society (Washington University School of Medicine)
Leonard W. Fabian Award (Washington University School of Medicine)

Dr. Christian Guay currently serves as Clinical Fellow in Critical Care and Cardiothoracic Anesthesiology at Massachusetts General Hospital and Harvard Medical School, and as Research Affiliate in The Picower Institute for Learning & Memory at MIT.

His main line of research focuses on the implementation of translational neuroscience in the operating room and intensive care unit, and on the development of methods to monitor and modulate states of consciousness in these settings. Complementary areas of research include sleep medicine and biomedical device development. Specific scientific expertise encompasses human sedation studies, sleep studies, clinical trials, target controlled infusions (TCI), electroencephalography (EEG) and brain computer interfaces (BCI).

The clinical trials listed below are automatically derived from ClinicalTrials.gov and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
NCT Short Title Overall Status Start Completion

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kafashan M, Brian Hickman L, Labonte AK, Huels ER, Maybrier H, Guay CS, Subramanian S, Farber NB, Ching S, Hogan RE, Kelz MB, Avidan MS, Mashour GA, Palanca BJA. Quiescence during burst suppression and postictal generalized EEG suppression are distinct patterns of activity. Clin Neurophysiol. 2022 10; 142:125-132. PMID: 36030576.
    Citations:    Fields:    Translation:Humans
  2. Guay CS, Kafashan M, Huels ER, Jiang Y, Beyoglu B, Spencer JW, Apakama G, Ju YS, Wildes TS, Avidan MS, Palanca BJA. Postoperative Delirium Severity, Features and Recovery Correlate With EEG. Anesth Analg. 2022. View Publication.
  3. Guay CS, Kafashan M, Huels ER, Jiang Y, Beyoglu B, Spencer JW, Geczi K, Apakama G, Ju YS, Wildes TS, Avidan MS, Palanca BJA. Postoperative Delirium Severity and Recovery Correlate With Electroencephalogram Spectral Features. Anesth Analg. 2022 May 13. PMID: 36130079; PMCID: PMC9653519.
    Citations:    Fields:    
  4. Li KM, Baddigam R, Bethel M, Guay CS, Song Z, Sullivan S, Gregory SH. Anesthetic considerations for transcatheter mitral and aortic valve procedures: An introduction and overview of current literature. Curr. Anesthesiol. Rep. 2021; 3(11):284-291.
  5. Gruenbaum SE, Guay CS, Gruenbaum BF, Konkayev A, Falegnami A, Qeva E, Prabhakar H, Nunes RR, Santoro A, Garcia DP, Quiñones-Hinojosa A, Bilotta F. Perioperative Glycemia Management in Patients Undergoing Craniotomy for Brain Tumor Resection: A Global Survey of Neuroanesthesiologists' Perceptions and Practices. World Neurosurg. 2021 11; 155:e548-e563. PMID: 34481106.
    Citations:    Fields:    Translation:HumansPHPublic Health
  6. Clephas PRD, Hoeks SE, Trivella M, Guay CS, Singh PM, Klimek M, Heesen M. Prognostic factors for chronic post-surgical pain after lung or pleural surgery: a protocol for a systematic review and meta-analysis. BMJ Open. 2021 06 15; 11(6):e051554. PMID: 34130966.
    Citations: 2     Fields:    Translation:Humans
  7. Guay CS, Khebir M, Shiva Shahiri T, Szilagyi A, Cole EE, Simoneau G, Badawy M. Evaluation of automated microvascular flow analysis software AVA 4: a validation study. Intensive Care Med Exp. 2021 Apr 02; 9(1):15. PMID: 33796954.
    Citations: 3     
  8. Kafashan MM, Hyche O, Nguyen T, Smith SK, Guay CS, Wilson E, Labonte AK, Guan MJ, Lucey BP, Ju YS, Palanca BJA. Perioperative sleep in geriatric cardiac surgical patients: a feasibility study using a wireless wearable device. Br J Anaesth. 2021 06; 126(6):e205-e208. PMID: 33812667.
    Citations: 1     Fields:    Translation:Humans
  9. Guay CS, Labonte AK, Montana MC, Landsness EC, Lucey BP, Kafashan M, Haroutounian S, Avidan MS, Brown EN, Palanca BJA. Closed-Loop Acoustic Stimulation During Sedation with Dexmedetomidine (CLASS-D): Protocol for a Within-Subject, Crossover, Controlled, Interventional Trial with Healthy Volunteers. Nat Sci Sleep. 2021; 13:303-313. PMID: 33692642; PMCID: PMC7939493.
  10. Hickman LB, Kafashan M, Labonte AK, Chan CW, Huels ER, Guay CS, Guan MJ, Ching S, Lenze EJ, Farber NB, Avidan MS, Hogan RE, Palanca BJA. Postictal generalized electroencephalographic suppression following electroconvulsive therapy: Temporal characteristics and impact of anesthetic regimen. Clin Neurophysiol. 2021 04; 132(4):977-983. PMID: 33652270.
    Citations: 1     Fields:    Translation:Humans
  11. Smith SK, Nguyen T, Labonte AK, Kafashan M, Hyche O, Guay CS, Wilson E, Chan CW, Luong A, Hickman LB, Fritz BA, Emmert D, Graetz TJ, Melby SJ, Lucey BP, Ju YS, Wildes TS, Avidan MS, Palanca BJA. Protocol for the Prognosticating Delirium Recovery Outcomes Using Wakefulness and Sleep Electroencephalography (P-DROWS-E) study: a prospective observational study of delirium in elderly cardiac surgical patients. BMJ Open. 2020 12 13; 10(12):e044295. PMID: 33318123.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  12. Palanca BJA, Guay CS. Associations between delirium and electroencephalographic markers: Notes from the field. Clin Neurophysiol. 2021 01; 132(1):210-211. PMID: 33218879.
    Citations: 1     Fields:    Translation:Humans
  13. Guay CS, Avidan MS. No Brain Is an Island. Anesth Analg. 2020 06; 130(6):1568-1571. PMID: 32384346.
    Citations: 1     Fields:    Translation:Humans
  14. Fogarty AE, Guay CS, Simoneau G, Colorado BS, Segal GR, Werner JK, Ellenbogen JM. Head Motion Predicts Transient Loss of Consciousness in Human Head Trauma: A Case-Control Study of Mixed Martial Artists. Am J Phys Med Rehabil. 2019 10; 98(10):859-865. PMID: 31441834.
    Citations: 1     Fields:    Translation:Humans
  15. Guay CS, Plourde G. Handgrip dynamometry for continuous assessment of volitional control during induction of anesthesia: a prospective observational study. Can J Anaesth. 2019 01; 66(1):48-56. PMID: 30229542.
    Citations: 2     Fields:    Translation:Humans
  16. Guay CS, Schanker BD. Neural Correlates of Pure Experience, Anesthesia and Meditation States. American Journal of Bioethics Neuroscience. 2018; 2(9):115-117. View Publication.
  17. Guay CS, Schanker BD. Brain-Computer Interfaces and Interactive Capacity in Patients with Disorders of Consciousness. American Journal of Bioethics Neuroscience. 2017; 3(8):141-142. View Publication.
  18. Guay CS, Ellenbogen JM. Emergency Sleep Medicine. Semin Neurol. 2017 08; 37(4):471-480. PMID: 28837994.
    Citations:    Fields:    Translation:HumansPHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.