Harvard Catalyst Profiles

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Joshua Elliott Lewis, M.D., Ph.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F30CA224968 (LEWIS, JOSHUA ELLIOTT) May 14, 2018 - May 13, 2021
    Systems biology modeling of radiation resistance and chemotherapy-radiation combination therapies in head and neck squamous cell carcinoma
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lewis JE, Kemp ML. Integration of machine learning and genome-scale metabolic modeling identifies multi-omics biomarkers for radiation resistance. Nat Commun. 2021 05 11; 12(1):2700. PMID: 33976213.
    Citations: 19     Fields:    Translation:HumansCells
  2. Lewis JE, Forshaw TE, Boothman DA, Furdui CM, Kemp ML. Personalized Genome-Scale Metabolic Models Identify Targets of Redox Metabolism in Radiation-Resistant Tumors. Cell Syst. 2021 01 20; 12(1):68-81.e11. PMID: 33476554.
    Citations: 6     Fields:    Translation:HumansCells
  3. Shukla K, Singh N, Lewis JE, Tsang AW, Boothman DA, Kemp ML, Furdui CM. MTHFD2 Blockade Enhances the Efficacy of ß-Lapachone Chemotherapy With Ionizing Radiation in Head and Neck Squamous Cell Cancer. Front Oncol. 2020; 10:536377. PMID: 33262939.
    Citations: 5     
  4. Paudel BB, Lewis JE, Hardeman KN, Hayford CE, Robbins CJ, Stauffer PE, Codreanu SG, Sherrod SD, McLean JA, Kemp ML, Quaranta V. An Integrative Gene Expression and Mathematical Flux Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells. Cancer Res. 2020 10 15; 80(20):4565-4577. PMID: 33060170.
    Citations: 2     Fields:    Translation:HumansCells
  5. Forshaw TE, Holmila R, Nelson KJ, Lewis JE, Kemp ML, Tsang AW, Poole LB, Lowther WT, Furdui CM. Peroxiredoxins in Cancer and Response to Radiation Therapies. Antioxidants (Basel). 2019 Jan 01; 8(1). PMID: 30609657.
    Citations: 17     
  6. Lewis JE, Singh N, Holmila RJ, Sumer BD, Williams NS, Furdui CM, Kemp ML, Boothman DA. Targeting NAD+ Metabolism to Enhance Radiation Therapy Responses. Semin Radiat Oncol. 2019 01; 29(1):6-15. PMID: 30573185.
    Citations: 13     Fields:    Translation:HumansCells
  7. Yousefi S, Amrollahi F, Amgad M, Dong C, Lewis JE, Song C, Gutman DA, Halani SH, Velazquez Vega JE, Brat DJ, Cooper LAD. Predicting clinical outcomes from large scale cancer genomic profiles with deep survival models. Sci Rep. 2017 09 15; 7(1):11707. PMID: 28916782; PMCID: PMC5601479.
    Citations: 55     Fields:    Translation:Humans
  8. Lewis JE, Costantini F, Mims J, Chen X, Furdui CM, Boothman DA, Kemp ML. Genome-Scale Modeling of NADPH-Driven ß-Lapachone Sensitization in Head and Neck Squamous Cell Carcinoma. Antioxid Redox Signal. 2018 10 01; 29(10):937-952. PMID: 28762750.
    Citations: 12     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.