Harvard Catalyst Profiles

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Alaric D'Souza, Ph.D., M.D.

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Biography
education and training
Yale University, New Haven, CTBS05/2014Ecology and Evolutionary Biology
Washington University in St. Louis, School of Medicine, St. Louis, MOMD05/2022Medicine
Washington University in St. Louis, School of Medicine, St. Louis, MOPhD05/2022Computational and Systems Biology

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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Anthony WE, Wang B, Sukhum KV, D'Souza AW, Hink T, Cass C, Seiler S, Reske KA, Coon C, Dubberke ER, Burnham CD, Dantas G, Kwon JH. Acute and persistent effects of commonly used antibiotics on the gut microbiome and resistome in healthy adults. Cell Rep. 2022 04 12; 39(2):110649. PMID: 35417701; PMCID: PMC9066705.
    Citations: 7     Fields:    Translation:HumansCells
  2. Stogios PJ, Bordeleau E, Xu Z, Skarina T, Evdokimova E, Chou S, Diorio-Toth L, D'Souza AW, Patel S, Dantas G, Wright GD, Savchenko A. Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol. 2022 03 25; 5(1):263. PMID: 35338238.
    Citations:    Translation:Cells
  3. D'Souza AW, Boolchandani M, Patel S, Galazzo G, van Hattem JM, Arcilla MS, Melles DC, de Jong MD, Schultsz C, Dantas G, Penders J. Destination shapes antibiotic resistance gene acquisitions, abundance increases, and diversity changes in Dutch travelers. Genome Med. 2021 06 07; 13(1):79. PMID: 34092249; PMCID: PMC8182900.
    Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
  4. Sukhum KV, Vargas RC, Boolchandani M, D'Souza AW, Patel S, Kesaraju A, Walljasper G, Hegde H, Ye Z, Valenzuela RK, Gunderson P, Bendixsen C, Dantas G, Shukla SK. Manure Microbial Communities and Resistance Profiles Reconfigure after Transition to Manure Pits and Differ from Those in Fertilized Field Soil. mBio. 2021 05 11; 12(3). PMID: 33975936.
    Citations: 1     Fields:    Translation:AnimalsPHPublic Health
  5. D'Souza AW, Moodley-Govender E, Berla B, Kelkar T, Wang B, Sun X, Daniels B, Coutsoudis A, Trehan I, Dantas G. Cotrimoxazole Prophylaxis Increases Resistance Gene Prevalence and a-Diversity but Decreases ß-Diversity in the Gut Microbiome of Human Immunodeficiency Virus-Exposed, Uninfected Infants. Clin Infect Dis. 2020 12 31; 71(11):2858-2868. PMID: 31832638.
    Citations: 16     Fields:    Translation:HumansCells
  6. Sun J, Liao XP, D'Souza AW, Boolchandani M, Li SH, Cheng K, Luis Martínez J, Li L, Feng YJ, Fang LX, Huang T, Xia J, Yu Y, Zhou YF, Sun YX, Deng XB, Zeng ZL, Jiang HX, Fang BH, Tang YZ, Lian XL, Zhang RM, Fang ZW, Yan QL, Dantas G, Liu YH. Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms. Nat Commun. 2020 03 18; 11(1):1427. PMID: 32188862.
    Citations: 47     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  7. Rafique M, Potter RF, Ferreiro A, Wallace MA, Rahim A, Ali Malik A, Siddique N, Abbas MA, D'Souza AW, Burnham CD, Ali N, Dantas G. Genomic Characterization of Antibiotic Resistant Escherichia coli Isolated From Domestic Chickens in Pakistan. Front Microbiol. 2019; 10:3052. PMID: 32010104.
    Citations: 12     
  8. Wardenburg KE, Potter RF, D'Souza AW, Hussain T, Wallace MA, Andleeb S, Burnham CD, Dantas G. Phenotypic and genotypic characterization of linezolid-resistant Enterococcus faecium from the USA and Pakistan. J Antimicrob Chemother. 2019 12 01; 74(12):3445-3452. PMID: 31504566.
    Citations: 18     Fields:    Translation:HumansCells
  9. Yarbrough ML, Wallace MA, Potter RF, D'Souza AW, Dantas G, Burnham CD. Breakpoint beware: reliance on historical breakpoints for Enterobacteriaceae leads to discrepancies in interpretation of susceptibility testing for carbapenems and cephalosporins and gaps in detection of carbapenem-resistant organisms. Eur J Clin Microbiol Infect Dis. 2020 Jan; 39(1):187-195. PMID: 31679102.
    Citations: 5     Fields:    Translation:HumansCells
  10. D'Souza AW, Potter RF, Wallace M, Shupe A, Patel S, Sun X, Gul D, Kwon JH, Andleeb S, Burnham CD, Dantas G. Spatiotemporal dynamics of multidrug resistant bacteria on intensive care unit surfaces. Nat Commun. 2019 10 08; 10(1):4569. PMID: 31594927.
    Citations: 22     Fields:    Translation:HumansCellsPHPublic Health
  11. Boolchandani M, D'Souza AW, Dantas G. Sequencing-based methods and resources to study antimicrobial resistance. Nat Rev Genet. 2019 06; 20(6):356-370. PMID: 30886350.
    Citations: 119     Fields:    Translation:HumansCells
  12. Baumann-Dudenhoeffer AM, D'Souza AW, Tarr PI, Warner BB, Dantas G. Infant diet and maternal gestational weight gain predict early metabolic maturation of gut microbiomes. Nat Med. 2018 12; 24(12):1822-1829. PMID: 30374198.
    Citations: 79     Fields:    Translation:HumansCells
  13. Potter RF, D'Souza AW, Wallace MA, Shupe A, Patel S, Gul D, Kwon JH, Beatty W, Andleeb S, Burnham CD, Dantas G. Superficieibacter electus gen. nov., sp. nov., an Extended-Spectrum ß-Lactamase Possessing Member of the Enterobacteriaceae Family, Isolated From Intensive Care Unit Surfaces. Front Microbiol. 2018; 9:1629. PMID: 30079059.
    Citations: 6     
  14. Potter RF, D'Souza AW, Wallace MA, Shupe A, Patel S, Gul D, Kwon JH, Andleeb S, Burnham CA, Dantas G. Draft Genome Sequence of the blaOXA-436- and blaNDM-1-Harboring Shewanella putrefaciens SA70 Isolate. Genome Announc. 2017 Jul 20; 5(29). PMID: 28729267.
    Citations: 4     
  15. Potter RF, D'Souza AW, Dantas G. The rapid spread of carbapenem-resistant Enterobacteriaceae. Drug Resist Updat. 2016 11; 29:30-46. PMID: 27912842; PMCID: PMC5140036.
    Citations: 122     Fields:    Translation:HumansCells
  16. D'Souza AW, Wagner GP. Malignant cancer and invasive placentation: A case for positive pleiotropy between endometrial and malignancy phenotypes. Evol Med Public Health. 2014 Oct 15; 2014(1):136-45. PMID: 25324490.
    Citations: 29     
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