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Alla V. Tsytsykova, Ph.D.

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Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hacein-Bey-Abina S, Pai SY, Gaspar HB, Armant M, Berry CC, Blanche S, Bleesing J, Blondeau J, de Boer H, Buckland KF, Caccavelli L, Cros G, De Oliveira S, Fern√°ndez KS, Guo D, Harris CE, Hopkins G, Lehmann LE, Lim A, London WB, van der Loo JC, Malani N, Male F, Malik P, Marinovic MA, McNicol AM, Moshous D, Neven B, Oleastro M, Picard C, Ritz J, Rivat C, Schambach A, Shaw KL, Sherman EA, Silberstein LE, Six E, Touzot F, Tsytsykova A, Xu-Bayford J, Baum C, Bushman FD, Fischer A, Kohn DB, Filipovich AH, Notarangelo LD, Cavazzana M, Williams DA, Thrasher AJ. A modified ?-retrovirus vector for X-linked severe combined immunodeficiency. N Engl J Med. 2014 Oct 09; 371(15):1407-17. PMID: 25295500.
    Citations: 65     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  2. Barteneva NS, Ponomarev ED, Tsytsykova A, Armant M, Vorobjev IA. Mitochondrial staining allows robust elimination of apoptotic and damaged cells during cell sorting. J Histochem Cytochem. 2014 Apr; 62(4):265-75. PMID: 24394470.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Via LE, Tsytsykova AV, Rajsbaum R, Falvo JV, Goldfeld AE. The transcription factor NFATp plays a key role in susceptibility to TB in mice. PLoS One. 2012; 7(7):e41427. PMID: 22844476.
    Citations: 2     Fields:    Translation:AnimalsCells
  4. Biglione S, Tsytsykova AV, Goldfeld AE. Monocyte-specific accessibility of a matrix attachment region in the tumor necrosis factor locus. J Biol Chem. 2011 Dec 23; 286(51):44126-33. PMID: 22027829.
    Citations: 2     Fields:    Translation:HumansCells
  5. Falvo JV, Tsytsykova AV, Goldfeld AE. Transcriptional control of the TNF gene. Curr Dir Autoimmun. 2010; 11:27-60. PMID: 20173386.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  6. Falvo JV, Lin CH, Tsytsykova AV, Hwang PK, Thanos D, Goldfeld AE, Maniatis T. A dimer-specific function of the transcription factor NFATp. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):19637-42. PMID: 19060202.
    Citations: 12     Fields:    Translation:Cells
  7. Tsytsykova AV, Rajsbaum R, Falvo JV, Ligeiro F, Neely SR, Goldfeld AE. Activation-dependent intrachromosomal interactions formed by the TNF gene promoter and two distal enhancers. Proc Natl Acad Sci U S A. 2007 Oct 23; 104(43):16850-5. PMID: 17940009.
    Citations: 34     Fields:    Translation:AnimalsCells
  8. Tsytsykova AV, Falvo JV, Schmidt-Supprian M, Courtois G, Thanos D, Goldfeld AE. Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression. J Biol Chem. 2007 Apr 20; 282(16):11629-38. PMID: 17303559.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  9. Ranjbar S, Tsytsykova AV, Lee SK, Rajsbaum R, Falvo JV, Lieberman J, Shankar P, Goldfeld AE. NFAT5 regulates HIV-1 in primary monocytes via a highly conserved long terminal repeat site. PLoS Pathog. 2006 Dec; 2(12):e130. PMID: 17173480.
    Citations: 20     Fields:    Translation:HumansCells
  10. Saraiva M, Christensen JR, Tsytsykova AV, Goldfeld AE, Ley SC, Kioussis D, O'Garra A. Identification of a macrophage-specific chromatin signature in the IL-10 locus. J Immunol. 2005 Jul 15; 175(2):1041-6. PMID: 16002704.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  11. Esensten JH, Tsytsykova AV, Lopez-Rodriguez C, Ligeiro FA, Rao A, Goldfeld AE. NFAT5 binds to the TNF promoter distinctly from NFATp, c, 3 and 4, and activates TNF transcription during hypertonic stress alone. Nucleic Acids Res. 2005; 33(12):3845-54. PMID: 16027109.
    Citations: 29     Fields:    Translation:AnimalsCells
  12. Barthel R, Tsytsykova AV, Barczak AK, Tsai EY, Dascher CC, Brenner MB, Goldfeld AE. Regulation of tumor necrosis factor alpha gene expression by mycobacteria involves the assembly of a unique enhanceosome dependent on the coactivator proteins CBP/p300. Mol Cell Biol. 2003 Jan; 23(2):526-33. PMID: 12509451.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  13. Tsytsykova AV, Goldfeld AE. Inducer-specific enhanceosome formation controls tumor necrosis factor alpha gene expression in T lymphocytes. Mol Cell Biol. 2002 Apr; 22(8):2620-31. PMID: 11909956.
    Citations: 30     Fields:    Translation:HumansCells
  14. Tsytsykova AV, Goldfeld AE. Nuclear factor of activated T cells transcription factor NFATp controls superantigen-induced lethal shock. J Exp Med. 2000 Aug 21; 192(4):581-6. PMID: 10952728.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  15. Tsai EY, Falvo JV, Tsytsykova AV, Barczak AK, Reimold AM, Glimcher LH, Fenton MJ, Gordon DC, Dunn IF, Goldfeld AE. A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo. Mol Cell Biol. 2000 Aug; 20(16):6084-94. PMID: 10913190.
    Citations: 85     Fields:    Translation:AnimalsCells
  16. Falvo JV, Brinkman BM, Tsytsykova AV, Tsai EY, Yao TP, Kung AL, Goldfeld AE. A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):3925-9. PMID: 10760264.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  17. Tsytsykova AV, Tsitsikov EN, Wright DA, Futcher B, Geha RS. The mouse genome contains two expressed intronless retroposed pseudogenes for the sentrin/sumo-1/PIC1 conjugating enzyme Ubc9. Mol Immunol. 1998 Nov; 35(16):1057-67. PMID: 10068040.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  18. Worm MM, Tsytsykova A, Geha RS. CD40 ligation and IL-4 use different mechanisms of transcriptional activation of the human lymphotoxin alpha promoter in B cells. Eur J Immunol. 1998 Mar; 28(3):901-6. PMID: 9541585.
    Citations: 9     Fields:    Translation:HumansCells
  19. Fujiwara H, Hanissian SH, Tsytsykova A, Geha RS. Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain. Proc Natl Acad Sci U S A. 1997 May 27; 94(11):5866-71. PMID: 9159166.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  20. Tsytsykova AV, Tsitsikov EN, Geha RS. The CD40L promoter contains nuclear factor of activated T cells-binding motifs which require AP-1 binding for activation of transcription. J Biol Chem. 1996 Feb 16; 271(7):3763-70. PMID: 8631992.
    Citations: 24     Fields:    Translation:AnimalsCells
  21. Trede NS, Tsytsykova AV, Chatila T, Goldfeld AE, Geha RS. Transcriptional activation of the human TNF-alpha promoter by superantigen in human monocytic cells: role of NF-kappa B. J Immunol. 1995 Jul 15; 155(2):902-8. PMID: 7608567.
    Citations: 39     Fields:    Translation:HumansCells
  22. Castigli E, Fuleihan R, Ramesh N, Tsitsikov E, Tsytsykova A, Geha RS. CD40 ligand/CD40 deficiency. Int Arch Allergy Immunol. 1995 May-Jun; 107(1-3):37-9. PMID: 7542090.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.