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Ka Yang, Ph.D.

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St. Jude Children's Research Hospital, Memphis, TNPostdoc02/2022Proteomic
University of Wisconsin-Madison, Madison, WIPhD08/2019Pharmaceutical Sciences

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yang K, Zhou Y, Roberts BL, Nie X, Tang W. Evaluation of the binding affinity of E3 ubiquitin ligase ligands by cellular target engagement and in-cell ELISA assay. STAR Protoc. 2021 03 19; 2(1):100288. PMID: 33532735.
    Citations:    Fields:    Translation:HumansCells
  2. Xie H, Yang K, Winston-McPherson GN, Stapleton DS, Keller MP, Attie AD, Smith KA, Tang W. From methylene bridged diindole to carbonyl linked benzimidazoleindole: Development of potent and metabolically stable PCSK9 modulators. Eur J Med Chem. 2020 Nov 15; 206:112678. PMID: 32823006.
    Citations: 2     Fields:    Translation:HumansAnimals
  3. Yang K, Zhao Y, Nie X, Wu H, Wang B, Almodovar-Rivera CM, Xie H, Tang W. A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders. Cell Chem Biol. 2020 07 16; 27(7):866-876.e8. PMID: 32413286.
    Citations: 9     Fields:    Translation:HumansCells
  4. Yang K, Wu H, Zhang Z, Leisten ED, Nie X, Liu B, Wen Z, Zhang J, Cunningham MD, Tang W. Development of Selective Histone Deacetylase 6 (HDAC6) Degraders Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. ACS Med Chem Lett. 2020 Apr 09; 11(4):575-581. PMID: 32292566.
    Citations: 25     
  5. Wu H, Liu B, Yang K, Winston-McPherson GN, Leisten ED, Vezina CM, Ricke WA, Peterson RE, Tang W. Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor. Bioorg Med Chem Lett. 2020 03 01; 30(5):126959. PMID: 31952965.
    Citations: 1     Fields:    Translation:HumansCells
  6. Wu H, Yang K, Zhang Z, Leisten ED, Li Z, Xie H, Liu J, Smith KA, Novakova Z, Barinka C, Tang W. Development of Multifunctional Histone Deacetylase 6 Degraders with Potent Antimyeloma Activity. J Med Chem. 2019 08 08; 62(15):7042-7057. PMID: 31271281.
    Citations: 38     Fields:    Translation:HumansCells
  7. Winston-McPherson GN, Xie H, Yang K, Li X, Shu D, Tang W. Discovery of 2,3'-diindolylmethanes as a novel class of PCSK9 modulators. Bioorg Med Chem Lett. 2019 08 15; 29(16):2345-2348. PMID: 31227343.
    Citations: 3     Fields:    Translation:HumansCells
  8. Yang K, Song Y, Xie H, Wu H, Wu YT, Leisten ED, Tang W. Development of the first small molecule histone deacetylase 6 (HDAC6) degraders. Bioorg Med Chem Lett. 2018 08 01; 28(14):2493-2497. PMID: 29871848.
    Citations: 53     Fields:    Translation:HumansCells
  9. Joshi SD, Kumar D, Dixit SR, Tigadi N, More UA, Lherbet C, Aminabhavi TM, Yang KS. Synthesis, characterization and antitubercular activities of novel pyrrolyl hydrazones and their Cu-complexes. Eur J Med Chem. 2016 Oct 04; 121:21-39. PMID: 27214509.
    Citations: 2     Fields:    Translation:HumansCells
  10. Joshi SD, Dixit SR, Kirankumar MN, Aminabhavi TM, Raju KV, Narayan R, Lherbet C, Yang KS. Synthesis, antimycobacterial screening and ligand-based molecular docking studies on novel pyrrole derivatives bearing pyrazoline, isoxazole and phenyl thiourea moieties. Eur J Med Chem. 2016 Jan 01; 107:133-52. PMID: 26580979.
    Citations: 13     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.