Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Agoston Agoston, Ph.D., M.D.

Profile Picture

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sauer MA, Yang J, Isidro RA, Dong F, Patil DT, Wee JO, Agoston AT, Deshpande V, Zhao L. Esophageal squamous cell carcinoma with basaloid features are genetically and prognostically similar to conventional squamous cell carcinoma. Mod Pathol. 2022 09; 35(9):1247-1253. PMID: 35351978.
    Citations:    Fields:    
  2. Chen W, Zhao L, Agoston A, White A, Mazzola E, Boyle PJ, Deshpande V, Hornick JL, Bueno R, Bass AJ, Enzinger P, Mamon H, Redston M, Patil DT. Florid Foreign Body-type Giant Cell Response to Keratin Is Associated With Improved Overall Survival in Patients Receiving Preoperative Therapy for Esophageal Squamous Cell Carcinoma. Am J Surg Pathol. 2021 12 01; 45(12):1648-1660. PMID: 34469333.
    Citations:    Fields:    Translation:Humans
  3. Isidro RA, Dong F, Hornick JL, Wee JO, Agoston A, Patil DT, Deshpande V, Zhao L. Verrucous carcinoma of the oesophagus is a genetically distinct subtype of oesophageal squamous cell carcinoma. Histopathology. 2021 Oct; 79(4):642-649. PMID: 33960520.
    Citations:    Fields:    Translation:Humans
  4. Huang J, Agoston AT, Guo P, Moses MA. A Rationally Designed ICAM1 Antibody Drug Conjugate for Pancreatic Cancer. Adv Sci (Weinh). 2020 Dec; 7(24):2002852. PMID: 33344137.
    Citations: 2     Fields:    
  5. Johncilla M, Odze RD, Agoston AT. Role of submucosal glands in the development and progression of carcinoma in Barrett's oesophagus. Pathology. 2020 Apr; 52(3):310-317. PMID: 32122647.
    Citations:    Fields:    Translation:Humans
  6. Ryou M, Lautz DB, Agoston AT, Thompson CC. Magnetic cholecysto-duodenal anastomosis. Minim Invasive Ther Allied Technol. 2021 Apr; 30(2):81-85. PMID: 31682532.
    Citations:    Fields:    Translation:Animals
  7. Ritterhouse LL, Wu EY, Kim WG, Dillon DA, Hirsch MS, Sholl LM, Agoston AT, Setia N, Lauwers GY, Park DY, Srivastava A, Doyle LA. Loss of SMAD4 protein expression in gastrointestinal and extra-gastrointestinal carcinomas. Histopathology. 2019 Oct; 75(4):546-551. PMID: 31054158.
    Citations: 11     Fields:    Translation:Humans
  8. Christakis AG, Papke DJ, Nowak JA, Yurgelun MB, Agoston AT, Lindeman NI, MacConaill LE, Sholl LM, Dong F. Targeted Cancer Next-Generation Sequencing as a Primary Screening Tool for Microsatellite Instability and Lynch Syndrome in Upper Gastrointestinal Tract Cancers. Cancer Epidemiol Biomarkers Prev. 2019 07; 28(7):1246-1251. PMID: 31028081.
    Citations: 3     Fields:    Translation:HumansCells
  9. Zhang Q, Agoston AT, Pham TH, Zhang W, Zhang X, Huo X, Peng S, Bajpai M, Das K, Odze RD, Spechler SJ, Souza RF. Acidic Bile Salts Induce Epithelial to Mesenchymal Transition via VEGF Signaling in Non-Neoplastic Barrett's Cells. Gastroenterology. 2019 01; 156(1):130-144.e10. PMID: 30268789; PMCID: PMC6309503.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  10. Agoston AT, Pham TH, Odze RD, Wang DH, Das KM, Spechler SJ, Souza RF. Columnar-Lined Esophagus Develops via Wound Repair in a Surgical Model of Reflux Esophagitis. Cell Mol Gastroenterol Hepatol. 2018; 6(4):389-404. PMID: 30186929; PMCID: PMC6122432.
    Citations: 9     Fields:    Translation:AnimalsCells
  11. Stachler MD, Camarda ND, Deitrick C, Kim A, Agoston AT, Odze RD, Hornick JL, Nag A, Thorner AR, Ducar M, Noffsinger A, Lash RH, Redston M, Carter SL, Davison JM, Bass AJ. Detection of Mutations in Barrett's Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma. Gastroenterology. 2018 07; 155(1):156-167. PMID: 29608884; PMCID: PMC6035092.
    Citations: 38     Fields:    Translation:Humans
  12. Jain N, Doyon JB, Lazarus JE, Schaefer IM, Johncilla ME, Agoston AT, Dalal AK, Velásquez GE. A Case of Disseminated Histoplasmosis in a Patient with Rheumatoid Arthritis on Abatacept. J Gen Intern Med. 2018 05; 33(5):769-772. PMID: 29532302; PMCID: PMC5910370.
    Citations: 1     Fields:    Translation:HumansAnimals
  13. Damian DD, Price K, Arabagi S, Berra I, Machaidze Z, Manjila S, Shimada S, Fabozzo A, Arnal G, Van Story D, Goldsmith JD, Agoston AT, Kim C, Jennings RW, Ngo PD, Manfredi M, Dupont PE. In vivo tissue regeneration with robotic implants. Sci Robot. 2018 01 10; 3(14). PMID: 33141697.
    Citations: 4     Fields:    
  14. Pectasides E, Stachler MD, Derks S, Liu Y, Maron S, Islam M, Alpert L, Kwak H, Kindler H, Polite B, Sharma MR, Allen K, O'Day E, Lomnicki S, Maranto M, Kanteti R, Fitzpatrick C, Weber C, Setia N, Xiao SY, Hart J, Nagy RJ, Kim KM, Choi MG, Min BH, Nason KS, O'Keefe L, Watanabe M, Baba H, Lanman R, Agoston AT, Oh DJ, Dunford A, Thorner AR, Ducar MD, Wollison BM, Coleman HA, Ji Y, Posner MC, Roggin K, Turaga K, Chang P, Hogarth K, Siddiqui U, Gelrud A, Ha G, Freeman SS, Rhoades J, Reed S, Gydush G, Rotem D, Davison J, Imamura Y, Adalsteinsson V, Lee J, Bass AJ, Catenacci DV. Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma. Cancer Discov. 2018 01; 8(1):37-48. PMID: 28978556.
    Citations: 105     Fields:    Translation:Humans
  15. Mito JK, Agoston AT, Dal Cin P, Srivastava A. Prevalence and significance of HMGA2 expression in oesophageal adenocarcinoma. Histopathology. 2017 Dec; 71(6):909-917. PMID: 28710822.
    Citations: 5     Fields:    Translation:Humans
  16. Agoston AT, Srivastava A, Zheng Y, Bueno R, Odze RD, Szallasi Z. Paraneoplastic thrombocytosis is associated with increased mortality and increased rate of lymph node metastasis in oesophageal adenocarcinoma. Pathology. 2017 Aug; 49(5):471-475. PMID: 28668174.
    Citations: 5     Fields:    Translation:Humans
  17. Aihara H, Drage MG, Agoston A, Thompson CC. Metastatic Breast Cancer Mimicking a Solitary Small Colonic Erosion. Am J Gastroenterol. 2017 May; 112(5):677. PMID: 28469218.
    Citations:    Fields:    Translation:Humans
  18. Drage MG, Tippayawong M, Agoston AT, Zheng Y, Bueno R, Hornick JL, Odze RD, Srivastava A. Morphological Features and Prognostic Significance of ARID1A-Deficient Esophageal Adenocarcinomas. Arch Pathol Lab Med. 2017 Jul; 141(7):970-977. PMID: 28440661.
    Citations: 5     Fields:    Translation:Humans
  19. Mathur R, Alver BH, San Roman AK, Wilson BG, Wang X, Agoston AT, Park PJ, Shivdasani RA, Roberts CW. ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice. Nat Genet. 2017 Feb; 49(2):296-302. PMID: 27941798; PMCID: PMC5285448.
    Citations: 130     Fields:    Translation:HumansAnimalsCells
  20. Nowak JA, Yurgelun MB, Bruce JL, Rojas-Rudilla V, Hall DL, Shivdasani P, Garcia EP, Agoston AT, Srivastava A, Ogino S, Kuo FC, Lindeman NI, Dong F. Detection of Mismatch Repair Deficiency and Microsatellite Instability in Colorectal Adenocarcinoma by Targeted Next-Generation Sequencing. J Mol Diagn. 2017 01; 19(1):84-91. PMID: 27863258.
    Citations: 52     Fields:    Translation:HumansCells
  21. Huo X, Agoston AT, Dunbar KB, Cipher DJ, Zhang X, Yu C, Cheng E, Zhang Q, Pham TH, Tambar UK, Bruick RK, Wang DH, Odze RD, Spechler SJ, Souza RF. Hypoxia-inducible factor-2a plays a role in mediating oesophagitis in GORD. Gut. 2017 09; 66(9):1542-1554. PMID: 27694141; PMCID: PMC5464991.
    Citations: 15     Fields:    Translation:HumansCellsCTClinical Trials
  22. Dunbar KB, Agoston AT, Odze RD, Huo X, Pham TH, Cipher DJ, Castell DO, Genta RM, Souza RF, Spechler SJ. Association of Acute Gastroesophageal Reflux Disease With Esophageal Histologic Changes. JAMA. 2016 May 17; 315(19):2104-12. PMID: 27187303; PMCID: PMC5030713.
    Citations: 53     Fields:    Translation:HumansCells
  23. Agoston AT, Strauss AC, Dulai PS, Hagen CE, Muzikansky A, Fudman DI, Abrams JA, Forcione DG, Jajoo K, Saltzman JR, Odze RD, Lauwers GY, Gordon SR, Lightdale CJ, Rothstein RI, Srivastava A. Predictors Of Treatment Failure After Radiofrequency Ablation For Intramucosal Adenocarcinoma in Barrett Esophagus: A Multi-institutional Retrospective Cohort Study. Am J Surg Pathol. 2016 Apr; 40(4):554-62. PMID: 26645729.
    Citations: 7     Fields:    Translation:Humans
  24. Setia N, Agoston AT, Han HS, Mullen JT, Duda DG, Clark JW, Deshpande V, Mino-Kenudson M, Srivastava A, Lennerz JK, Hong TS, Kwak EL, Lauwers GY. A protein and mRNA expression-based classification of gastric cancer. Mod Pathol. 2016 07; 29(7):772-84. PMID: 27032689.
    Citations: 49     Fields:    Translation:HumansCells
  25. Ryou M, Agoston AT, Thompson CC. Endoscopic intestinal bypass creation by using self-assembling magnets in a porcine model. Gastrointest Endosc. 2016 Apr; 83(4):821-5. PMID: 26522371.
    Citations: 11     Fields:    Translation:Animals
  26. Johncilla M, Misdraji J, Pratt DS, Agoston AT, Lauwers GY, Srivastava A, Doyle LA. Ipilimumab-associated Hepatitis: Clinicopathologic Characterization in a Series of 11 Cases. Am J Surg Pathol. 2015 Aug; 39(8):1075-84. PMID: 26034866.
    Citations: 65     Fields:    Translation:Humans
  27. Agoston AT, Zheng Y, Bueno R, Lauwers GY, Odze RD, Srivastava A. Predictors of Disease Recurrence and Survival in Esophageal Adenocarcinomas With Complete Response to Neoadjuvant Therapy. Am J Surg Pathol. 2015 Aug; 39(8):1085-92. PMID: 26076061.
    Citations: 9     Fields:    Translation:Humans
  28. Stachler MD, Taylor-Weiner A, Peng S, McKenna A, Agoston AT, Odze RD, Davison JM, Nason KS, Loda M, Leshchiner I, Stewart C, Stojanov P, Seepo S, Lawrence MS, Ferrer-Torres D, Lin J, Chang AC, Gabriel SB, Lander ES, Beer DG, Getz G, Carter SL, Bass AJ. Paired exome analysis of Barrett's esophagus and adenocarcinoma. Nat Genet. 2015 Sep; 47(9):1047-55. PMID: 26192918; PMCID: PMC4552571.
    Citations: 146     Fields:    Translation:Humans
  29. Spector R, Zheng Y, Yeap BY, Wee JO, Lebenthal A, Swanson SJ, Marchosky DE, Enzinger PC, Mamon HJ, Lerut A, Odze R, Srivastava A, Agoston AT, Tippayawang M, Bueno R. The 3-Hole Minimally Invasive Esophagectomy: A Safe Procedure Following Neoadjuvant Chemotherapy and Radiation. Semin Thorac Cardiovasc Surg. 2015; 27(2):205-15. PMID: 26686448.
    Citations: 8     Fields:    Translation:Humans
  30. Ince TA, Sousa AD, Jones MA, Harrell JC, Agoston ES, Krohn M, Selfors LM, Liu W, Chen K, Yong M, Buchwald P, Wang B, Hale KS, Cohick E, Sergent P, Witt A, Kozhekbaeva Z, Gao S, Agoston AT, Merritt MA, Foster R, Rueda BR, Crum CP, Brugge JS, Mills GB. Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours. Nat Commun. 2015 Jun 17; 6:7419. PMID: 26080861.
    Citations: 84     Fields:    Translation:HumansCells
  31. Yu C, Huo X, Agoston AT, Zhang X, Theiss AL, Cheng E, Zhang Q, Zaika A, Pham TH, Wang DH, Lobie PE, Odze RD, Spechler SJ, Souza RF. Mitochondrial STAT3 contributes to transformation of Barrett's epithelial cells that express oncogenic Ras in a p53-independent fashion. Am J Physiol Gastrointest Liver Physiol. 2015 Aug 01; 309(3):G146-61. PMID: 26045618; PMCID: PMC4525109.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  32. Asanuma K, Huo X, Agoston A, Zhang X, Yu C, Cheng E, Zhang Q, Dunbar KB, Pham TH, Wang DH, Iijima K, Shimosegawa T, Odze RD, Spechler SJ, Souza RF. In oesophageal squamous cells, nitric oxide causes S-nitrosylation of Akt and blocks SOX2 (sex determining region Y-box 2) expression. Gut. 2016 09; 65(9):1416-26. PMID: 25986942; PMCID: PMC4651671.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  33. Lin W, Watanabe H, Peng S, Francis JM, Kaplan N, Pedamallu CS, Ramachandran A, Agoston A, Bass AJ, Meyerson M. Dynamic epigenetic regulation by menin during pancreatic islet tumor formation. Mol Cancer Res. 2015 Apr; 13(4):689-98. PMID: 25537453.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  34. Strauss AC, Agoston AT, Dulai PS, Srivastava A, Rothstein RI. Radiofrequency ablation for Barrett's-associated intramucosal carcinoma: a multi-center follow-up study. Surg Endosc. 2014 Dec; 28(12):3366-72. PMID: 24950726.
    Citations: 10     Fields:    Translation:Humans
  35. Castroneves LA, Jugo RH, Maynard MA, Lee JS, Wassner AJ, Dorfman D, Bronson RT, Ukomadu C, Agoston AT, Ding L, Luongo C, Guo C, Song H, Demchev V, Lee NY, Feldman HA, Vella KR, Peake RW, Hartigan C, Kellogg MD, Desai A, Salvatore D, Dentice M, Huang SA. Mice with hepatocyte-specific deficiency of type 3 deiodinase have intact liver regeneration and accelerated recovery from nonthyroidal illness after toxin-induced hepatonecrosis. Endocrinology. 2014 Oct; 155(10):4061-8. PMID: 25004090; PMCID: PMC4164928.
    Citations: 2     Fields:    Translation:AnimalsCells
  36. Agoston AT, Odze RD. Evidence that gastric pit dysplasia-like atypia is a neoplastic precursor lesion. Hum Pathol. 2014 Mar; 45(3):446-55. PMID: 24529328.
    Citations: 7     Fields:    Translation:Humans
  37. Kis B, O'Regan KN, Agoston A, Javery O, Jagannathan J, Ramaiya NH. Imaging of desmoplastic small round cell tumour in adults. Br J Radiol. 2012 Feb; 85(1010):187-92. PMID: 22128126; PMCID: PMC3473944.
    Citations: 15     Fields:    Translation:Humans
  38. Huang Q, Fan X, Agoston AT, Feng A, Yu H, Lauwers G, Zhang L, Odze RD. Comparison of gastro-oesophageal junction carcinomas in Chinese versus American patients. Histopathology. 2011 Aug; 59(2):188-97. PMID: 21884197.
    Citations: 15     Fields:    Translation:Humans
  39. Agoston AT, Liang CW, Richkind KE, Fletcher JA, Vargas SO. Trisomy 18 is a consistent cytogenetic feature in pilomatricoma. Mod Pathol. 2010 Aug; 23(8):1147-50. PMID: 20495544.
    Citations: 4     Fields:    Translation:HumansCells
  40. Gamper CJ, Agoston AT, Nelson WG, Powell JD. Identification of DNA methyltransferase 3a as a T cell receptor-induced regulator of Th1 and Th2 differentiation. J Immunol. 2009 Aug 15; 183(4):2267-76. PMID: 19625655; PMCID: PMC2818975.
    Citations: 49     Fields:    Translation:AnimalsCells
  41. Zhou Q, Agoston AT, Atadja P, Nelson WG, Davidson NE. Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells. Mol Cancer Res. 2008 May; 6(5):873-83. PMID: 18505931.
    Citations: 78     Fields:    Translation:HumansCells
  42. Agoston AT, Argani P, De Marzo AM, Hicks JL, Nelson WG. Retinoblastoma pathway dysregulation causes DNA methyltransferase 1 overexpression in cancer via MAD2-mediated inhibition of the anaphase-promoting complex. Am J Pathol. 2007 May; 170(5):1585-93. PMID: 17456764; PMCID: PMC1854953.
    Citations: 7     Fields:    Translation:Humans
  43. Nelson WG, Yegnasubramanian S, Agoston AT, Bastian PJ, Lee BH, Nakayama M, De Marzo AM. Abnormal DNA methylation, epigenetics, and prostate cancer. Front Biosci. 2007 May 01; 12:4254-66. PMID: 17485372.
    Citations: 55     Fields:    Translation:HumansCells
  44. Agoston AT, Argani P, Yegnasubramanian S, De Marzo AM, Ansari-Lari MA, Hicks JL, Davidson NE, Nelson WG. Increased protein stability causes DNA methyltransferase 1 dysregulation in breast cancer. J Biol Chem. 2005 May 06; 280(18):18302-10. PMID: 15755728.
    Citations: 50     Fields:    Translation:HumansCells
  45. Qayyum A, Birdwell RL, Daniel BL, Nowels KW, Jeffrey SS, Agoston TA, Herfkens RJ. MR imaging features of infiltrating lobular carcinoma of the breast: histopathologic correlation. AJR Am J Roentgenol. 2002 May; 178(5):1227-32. PMID: 11959737.
    Citations: 13     Fields:    Translation:Humans
  46. Agoston AT, Daniel BL, Herfkens RJ, Ikeda DM, Birdwell RL, Heiss SG, Sawyer-Glover AM. Intensity-modulated parametric mapping for simultaneous display of rapid dynamic and high-spatial-resolution breast MR imaging data. Radiographics. 2001 Jan-Feb; 21(1):217-26. PMID: 11158656.
    Citations: 9     Fields:    Translation:Humans
  47. de Crespigny AJ, Howard D, D'Arceuil H, Muller H, Agoston AT, Seri S, Hashiguchi Y, Fujimoto C, Nakatani A, Moseley ME. Dynamic contrast-enhanced MRI of Implanted VX2 tumors in rabbit muscle: comparison of Gd-DTPA and NMS60. Magn Reson Imaging. 1999 Nov; 17(9):1297-305. PMID: 10576715.
    Citations: 5     Fields:    Translation:Animals
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Agoston's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (272)
Co-Authors (75)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.