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Michael Grusby, Ph.D.

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Northwestern UniversityPh.D1988

Dr. Grusby's research interests have been on the role of a class of transcription factors called signal transducer and activator of transcription (STATs) in the differentiation and function of T helper cell subsets. Studies from his lab have shown how manipulating STAT activity can alter the function of T helper cells and therefore change the outcome of conditions such as asthma and other inflammatory diseases. In addition, Dr. Grusby has published a number of studies on the biology of the cytokine IL-21, demonstrating its critical role in the development of diabetes. Dr. Grusby served as the past Director of the PhD in Biological Sciences in Public Health (BPH) Program within the Division of Biological Sciences and as a member of the Steering Committee for the Office for Educational Programs.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01GM062135 (GRUSBY, MICHAEL J) Feb 1, 2001 - Jan 31, 2005
    Role: Principal Investigator
  2. R01AI040171 (GRUSBY, MICHAEL J) May 1, 1997 - Feb 28, 2008
    Regulation of Differentiation &Function of TH2 Cells
    Role: Principal Investigator
  3. R21AI040171 (GRUSBY, MICHAEL J) Sep 15, 1996 - Sep 14, 1997
    Role: Principal Investigator
  4. R29CA056462 (GRUSBY, MICHAEL J) May 1, 1992 - Apr 30, 1997
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Cao D, Ma X, Cai J, Luan J, Liu AJ, Yang R, Cao Y, Zhu X, Zhang H, Chen YX, Shi Y, Shi GX, Zou D, Cao X, Grusby MJ, Xie Z, Zhang WJ. ZBTB20 is required for anterior pituitary development and lactotrope specification. Nat Commun. 2016 Apr 15; 7:11121. PMID: 27079169.
    Citations: 16     Fields:    Translation:AnimalsCells
  2. Lajoie S, Lewkowich I, Herman NS, Sproles A, Pesce JT, Wynn TA, Grusby MJ, Hamid Q, Wills-Karp M. IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses. Clin Exp Allergy. 2014 Jul; 44(7):976-85. PMID: 24807637.
    Citations: 16     Fields:    Translation:AnimalsCells
  3. Sutherland AP, Joller N, Michaud M, Liu SM, Kuchroo VK, Grusby MJ. IL-21 promotes CD8+ CTL activity via the transcription factor T-bet. J Immunol. 2013 Apr 15; 190(8):3977-84. PMID: 23479229.
    Citations: 47     Fields:    Translation:AnimalsCells
  4. Qu Z, Fu J, Ma H, Zhou J, Jin M, Mapara MY, Grusby MJ, Xiao G. PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease. Cell Biosci. 2012 Jun 25; 2(1):23. PMID: 22731402.
    Citations: 19     
  5. Zhang Y, Xie Z, Zhou L, Li L, Zhang H, Zhou G, Ma X, Herrera PL, Liu Z, Grusby MJ, Zhang WJ. The zinc finger protein ZBTB20 regulates transcription of fructose-1,6-bisphosphatase 1 and ß cell function in mice. Gastroenterology. 2012 Jun; 142(7):1571-1580.e6. PMID: 22374165.
    Citations: 18     Fields:    Translation:AnimalsCells
  6. Tanaka T, Yamamoto Y, Muromoto R, Ikeda O, Sekine Y, Grusby MJ, Kaisho T, Matsuda T. PDLIM2 inhibits T helper 17 cell development and granulomatous inflammation through degradation of STAT3. Sci Signal. 2011 Dec 06; 4(202):ra85. PMID: 22155789.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  7. Qu Z, Yan P, Fu J, Jiang J, Grusby MJ, Smithgall TE, Xiao G. DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target. Cancer Res. 2010 Mar 01; 70(5):1766-72. PMID: 20145149.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  8. Fathman JW, Gurish MF, Hemmers S, Bonham K, Friend DS, Grusby MJ, Glimcher LH, Mowen KA. NIP45 controls the magnitude of the type 2 T helper cell response. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3663-8. PMID: 20133688.
    Citations: 13     Fields:    Translation:AnimalsCells
  9. Hiramatsu Y, Suto A, Kashiwakuma D, Kanari H, Kagami S, Ikeda K, Hirose K, Watanabe N, Grusby MJ, Iwamoto I, Nakajima H. c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-beta inhibits c-Maf-induced IL-21 production in CD4+ T cells. J Leukoc Biol. 2010 Apr; 87(4):703-12. PMID: 20042469.
    Citations: 65     Fields:    Translation:AnimalsCells
  10. Sutherland AP, Zhang H, Zhang Y, Michaud M, Xie Z, Patti ME, Grusby MJ, Zhang WJ. Zinc finger protein Zbtb20 is essential for postnatal survival and glucose homeostasis. Mol Cell Biol. 2009 May; 29(10):2804-15. PMID: 19273596.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  11. Zullo AJ, Michaud M, Zhang W, Grusby MJ. Identification of the small protein rich in arginine and glycine (SRAG): a newly identified nucleolar protein that can regulate cell proliferation. J Biol Chem. 2009 May 01; 284(18):12504-11. PMID: 19254951.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  12. Sutherland AP, Van Belle T, Wurster AL, Suto A, Michaud M, Zhang D, Grusby MJ, von Herrath M. Interleukin-21 is required for the development of type 1 diabetes in NOD mice. Diabetes. 2009 May; 58(5):1144-55. PMID: 19208913; PMCID: PMC2671036.
    Citations: 81     Fields:    Translation:AnimalsCells
  13. Yan P, Fu J, Qu Z, Li S, Tanaka T, Grusby MJ, Xiao G. PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation. Blood. 2009 Apr 30; 113(18):4370-80. PMID: 19131544; PMCID: PMC2676091.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  14. Jin H, Oyoshi MK, Le Y, Bianchi T, Koduru S, Mathias CB, Kumar L, Le Bras S, Young D, Collins M, Grusby MJ, Wenzel J, Bieber T, Boes M, Silberstein LE, Oettgen HC, Geha RS. IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice. J Clin Invest. 2009 Jan; 119(1):47-60. PMID: 19075398; PMCID: PMC2613448.
    Citations: 39     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  15. Xie Z, Zhang H, Tsai W, Zhang Y, Du Y, Zhong J, Szpirer C, Zhu M, Cao X, Barton MC, Grusby MJ, Zhang WJ. Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):10859-64. PMID: 18669658.
    Citations: 52     Fields:    Translation:AnimalsCells
  16. Suto A, Kashiwakuma D, Kagami S, Hirose K, Watanabe N, Yokote K, Saito Y, Nakayama T, Grusby MJ, Iwamoto I, Nakajima H. Development and characterization of IL-21-producing CD4+ T cells. J Exp Med. 2008 Jun 09; 205(6):1369-79. PMID: 18474630.
    Citations: 111     Fields:    Translation:AnimalsCells
  17. Zheng T, Liu W, Oh SY, Zhu Z, Hu B, Homer RJ, Cohn L, Grusby MJ, Elias JA. IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung. J Immunol. 2008 Jan 01; 180(1):522-9. PMID: 18097054.
    Citations: 37     Fields:    Translation:Animals
  18. Becskei A, Grusby MJ. Contribution of IL-12R mediated feedback loop to Th1 cell differentiation. FEBS Lett. 2007 Nov 13; 581(27):5199-206. PMID: 17950290.
    Citations: 15     Fields:    Translation:AnimalsCells
  19. Touma M, Antonini V, Kumar M, Osborn SL, Bobenchik AM, Keskin DB, Connolly JE, Grusby MJ, Reinherz EL, Clayton LK. Functional role for I kappa BNS in T cell cytokine regulation as revealed by targeted gene disruption. J Immunol. 2007 Aug 01; 179(3):1681-92. PMID: 17641034.
    Citations: 21     Fields:    Translation:AnimalsCells
  20. Tanaka T, Grusby MJ, Kaisho T. PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit. Nat Immunol. 2007 Jun; 8(6):584-91. PMID: 17468759.
    Citations: 138     Fields:    Translation:HumansAnimalsCells
  21. Nakahira M, Tanaka T, Robson BE, Mizgerd JP, Grusby MJ. Regulation of signal transducer and activator of transcription signaling by the tyrosine phosphatase PTP-BL. Immunity. 2007 Feb; 26(2):163-76. PMID: 17306571.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  22. Gao C, Guo H, Mi Z, Grusby MJ, Kuo PC. Osteopontin induces ubiquitin-dependent degradation of STAT1 in RAW264.7 murine macrophages. J Immunol. 2007 Feb 01; 178(3):1870-81. PMID: 17237438.
    Citations: 24     Fields:    Translation:AnimalsCells
  23. Keane MP, Gomperts BN, Weigt S, Xue YY, Burdick MD, Nakamura H, Zisman DA, Ardehali A, Saggar R, Lynch JP, Hogaboam C, Kunkel SL, Lukacs NW, Ross DJ, Grusby MJ, Strieter RM, Belperio JA. IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome. J Immunol. 2007 Jan 01; 178(1):511-9. PMID: 17182591.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  24. Suto A, Wurster AL, Reiner SL, Grusby MJ. IL-21 inhibits IFN-gamma production in developing Th1 cells through the repression of Eomesodermin expression. J Immunol. 2006 Sep 15; 177(6):3721-7. PMID: 16951332.
    Citations: 54     Fields:    Translation:AnimalsCells
  25. Pesce J, Kaviratne M, Ramalingam TR, Thompson RW, Urban JF, Cheever AW, Young DA, Collins M, Grusby MJ, Wynn TA. The IL-21 receptor augments Th2 effector function and alternative macrophage activation. J Clin Invest. 2006 Jul; 116(7):2044-55. PMID: 16778988; PMCID: PMC1479424.
    Citations: 146     Fields:    Translation:AnimalsCells
  26. Huang H, Kearney JF, Grusby MJ, Benoist C, Mathis D. Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen. Proc Natl Acad Sci U S A. 2006 Mar 07; 103(10):3734-9. PMID: 16505356; PMCID: PMC1450147.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  27. Tanaka T, Soriano MA, Grusby MJ. SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling. Immunity. 2005 Jun; 22(6):729-36. PMID: 15963787.
    Citations: 85     Fields:    Translation:AnimalsCells
  28. Mehta DS, Wurster AL, Weinmann AS, Grusby MJ. NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression. Proc Natl Acad Sci U S A. 2005 Feb 08; 102(6):2016-21. PMID: 15684054; PMCID: PMC548571.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  29. Mehta DS, Wurster AL, Grusby MJ. Biology of IL-21 and the IL-21 receptor. Immunol Rev. 2004 Dec; 202:84-95. PMID: 15546387.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  30. Liu Q, Arseculeratne C, Liu Z, Whitmire J, Grusby MJ, Finkelman FD, Darling TN, Cheever AW, Swearengen J, Urban JF, Gause WC. Simultaneous deficiency in CD28 and STAT6 results in chronic ectoparasite-induced inflammatory skin disease. Infect Immun. 2004 Jul; 72(7):3706-15. PMID: 15213110; PMCID: PMC427407.
    Citations: 6     Fields:    Translation:AnimalsCells
  31. Chitnis T, Salama AD, Grusby MJ, Sayegh MH, Khoury SJ. Defining Th1 and Th2 immune responses in a reciprocal cytokine environment in vivo. J Immunol. 2004 Apr 01; 172(7):4260-5. PMID: 15034039.
    Citations: 6     Fields:    Translation:AnimalsCells
  32. Satake Y, Diaz BL, Balestrieri B, Lam BK, Kanaoka Y, Grusby MJ, Arm JP. Role of group V phospholipase A2 in zymosan-induced eicosanoid generation and vascular permeability revealed by targeted gene disruption. J Biol Chem. 2004 Apr 16; 279(16):16488-94. PMID: 14761945.
    Citations: 68     Fields:    Translation:Animals
  33. Mentink-Kane MM, Cheever AW, Thompson RW, Hari DM, Kabatereine NB, Vennervald BJ, Ouma JH, Mwatha JK, Jones FM, Donaldson DD, Grusby MJ, Dunne DW, Wynn TA. IL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis. Proc Natl Acad Sci U S A. 2004 Jan 13; 101(2):586-90. PMID: 14699044; PMCID: PMC327191.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  34. Ma HL, Whitters MJ, Konz RF, Senices M, Young DA, Grusby MJ, Collins M, Dunussi-Joannopoulos K. IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-gamma. J Immunol. 2003 Jul 15; 171(2):608-15. PMID: 12847225.
    Citations: 45     Fields:    Translation:AnimalsCells
  35. Mehta DS, Wurster AL, Whitters MJ, Young DA, Collins M, Grusby MJ. IL-21 induces the apoptosis of resting and activated primary B cells. J Immunol. 2003 Apr 15; 170(8):4111-8. PMID: 12682241.
    Citations: 64     Fields:    Translation:AnimalsCells
  36. Akbari O, Stock P, Meyer E, Kronenberg M, Sidobre S, Nakayama T, Taniguchi M, Grusby MJ, DeKruyff RH, Umetsu DT. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nat Med. 2003 May; 9(5):582-8. PMID: 12669034.
    Citations: 266     Fields:    Translation:AnimalsCells
  37. Wood N, Whitters MJ, Jacobson BA, Witek J, Sypek JP, Kasaian M, Eppihimer MJ, Unger M, Tanaka T, Goldman SJ, Collins M, Donaldson DD, Grusby MJ. Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2. J Exp Med. 2003 Mar 17; 197(6):703-9. PMID: 12642602; PMCID: PMC2193851.
    Citations: 79     Fields:    Translation:AnimalsCells
  38. Chiaramonte MG, Mentink-Kane M, Jacobson BA, Cheever AW, Whitters MJ, Goad ME, Wong A, Collins M, Donaldson DD, Grusby MJ, Wynn TA. Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response. J Exp Med. 2003 Mar 17; 197(6):687-701. PMID: 12642601; PMCID: PMC2193852.
    Citations: 113     Fields:    Translation:HumansAnimalsCells
  39. Bream JH, Curiel RE, Yu CR, Egwuagu CE, Grusby MJ, Aune TM, Young HA. IL-4 synergistically enhances both IL-2- and IL-12-induced IFN-gamma expression in murine NK cells. Blood. 2003 Jul 01; 102(1):207-14. PMID: 12637316.
    Citations: 24     Fields:    Translation:AnimalsCells
  40. Chung DR, Kasper DL, Panzo RJ, Chitnis T, Grusby MJ, Sayegh MH, Tzianabos AO, Chtinis T. CD4+ T cells mediate abscess formation in intra-abdominal sepsis by an IL-17-dependent mechanism. J Immunol. 2003 Feb 15; 170(4):1958-63. PMID: 12574364.
    Citations: 98     Fields:    Translation:AnimalsCells
  41. Wurster AL, Rodgers VL, Satoskar AR, Whitters MJ, Young DA, Collins M, Grusby MJ. Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells. J Exp Med. 2002 Oct 07; 196(7):969-77. PMID: 12370258; PMCID: PMC2194031.
    Citations: 80     Fields:    Translation:AnimalsCells
  42. Finnegan A, Grusby MJ, Kaplan CD, O'Neill SK, Eibel H, Koreny T, Czipri M, Mikecz K, Zhang J. IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms. J Immunol. 2002 Sep 15; 169(6):3345-52. PMID: 12218156.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  43. Eyles JL, Metcalf D, Grusby MJ, Hilton DJ, Starr R. Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1. J Biol Chem. 2002 Nov 15; 277(46):43735-40. PMID: 12221108.
    Citations: 39     Fields:    Translation:AnimalsCells
  44. Wurster AL, Rodgers VL, White MF, Rothstein TL, Grusby MJ. Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL. J Biol Chem. 2002 Jul 26; 277(30):27169-75. PMID: 12023955.
    Citations: 50     Fields:    Translation:AnimalsCells
  45. Kasaian MT, Whitters MJ, Carter LL, Lowe LD, Jussif JM, Deng B, Johnson KA, Witek JS, Senices M, Konz RF, Wurster AL, Donaldson DD, Collins M, Young DA, Grusby MJ. IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity. Immunity. 2002 Apr; 16(4):559-69. PMID: 11970879.
    Citations: 145     Fields:    Translation:AnimalsCells
  46. Wurster AL, Withers DJ, Uchida T, White MF, Grusby MJ. Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis. Mol Cell Biol. 2002 Jan; 22(1):117-26. PMID: 11739727.
    Citations: 32     Fields:    Translation:AnimalsCells
  47. Lim YC, Xie H, Come CE, Alexander SI, Grusby MJ, Lichtman AH, Luscinskas FW. IL-12, STAT4-dependent up-regulation of CD4(+) T cell core 2 beta-1,6-n-acetylglucosaminyltransferase, an enzyme essential for biosynthesis of P-selectin ligands. J Immunol. 2001 Oct 15; 167(8):4476-84. PMID: 11591774.
    Citations: 23     Fields:    Translation:AnimalsCells
  48. Chitnis T, Najafian N, Benou C, Salama AD, Grusby MJ, Sayegh MH, Khoury SJ. Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis. J Clin Invest. 2001 Sep; 108(5):739-47. PMID: 11544280; PMCID: PMC209380.
    Citations: 93     Fields:    Translation:AnimalsCells
  49. Reimold AM, Iwakoshi NN, Manis J, Vallabhajosyula P, Szomolanyi-Tsuda E, Gravallese EM, Friend D, Grusby MJ, Alt F, Glimcher LH. Plasma cell differentiation requires the transcription factor XBP-1. Nature. 2001 Jul 19; 412(6844):300-7. PMID: 11460154.
    Citations: 532     Fields:    Translation:AnimalsCells
  50. Daheshia M, Friend DS, Grusby MJ, Austen KF, Katz HR. Increased severity of local and systemic anaphylactic reactions in gp49B1-deficient mice. J Exp Med. 2001 Jul 16; 194(2):227-34. PMID: 11457897; PMCID: PMC2193448.
    Citations: 15     Fields:    Translation:AnimalsCells
  51. Exley MA, Bigley NJ, Cheng O, Tahir SM, Smiley ST, Carter QL, Stills HF, Grusby MJ, Koezuka Y, Taniguchi M, Balk SP. CD1d-reactive T-cell activation leads to amelioration of disease caused by diabetogenic encephalomyocarditis virus. J Leukoc Biol. 2001 May; 69(5):713-8. PMID: 11358978.
    Citations: 49     Fields:    Translation:AnimalsCells
  52. Zhou P, Szot G, Guo Z, Kim O, He G, Wang J, Grusby M, Newell K, Thistlethwaite J, Bluestone J, Alegre M. Role of STAT6 signaling in the induction and long-term maintenance of tolerance mediated by CTLA4-Ig. Transplant Proc. 2001 Feb-Mar; 33(1-2):214-6. PMID: 11266784.
    Citations:    Fields:    Translation:AnimalsCells
  53. Lawless VA, Zhang S, Ozes ON, Bruns HA, Oldham I, Hoey T, Grusby MJ, Kaplan MH. Stat4 regulates multiple components of IFN-gamma-inducing signaling pathways. J Immunol. 2000 Dec 15; 165(12):6803-8. PMID: 11120802.
    Citations: 37     Fields:    Translation:AnimalsCells
  54. Ostrand-Rosenberg S, Grusby MJ, Clements VK. Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma. J Immunol. 2000 Dec 01; 165(11):6015-9. PMID: 11086031.
    Citations: 46     Fields:    Translation:AnimalsCells
  55. Zhou P, Szot GL, Guo Z, Kim O, He G, Wang J, Grusby MJ, Newell KA, Thistlethwaite JR, Bluestone JA, Alegre ML. Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance. J Immunol. 2000 Nov 15; 165(10):5580-7. PMID: 11067913.
    Citations: 16     Fields:    Translation:AnimalsCells
  56. Tarleton RL, Grusby MJ, Zhang L. Increased susceptibility of Stat4-deficient and enhanced resistance in Stat6-deficient mice to infection with Trypanosoma cruzi. J Immunol. 2000 Aug 01; 165(3):1520-5. PMID: 10903759.
    Citations: 37     Fields:    Translation:AnimalsCells
  57. Kishimoto K, Dong VM, Issazadeh S, Fedoseyeva EV, Waaga AM, Yamada A, Sho M, Benichou G, Auchincloss H, Grusby MJ, Khoury SJ, Sayegh MH. The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo. J Clin Invest. 2000 Jul; 106(1):63-72. PMID: 10880049; PMCID: PMC314364.
    Citations: 28     Fields:    Translation:AnimalsCells
  58. Wurster AL, Tanaka T, Grusby MJ. The biology of Stat4 and Stat6. Oncogene. 2000 May 15; 19(21):2577-84. PMID: 10851056.
    Citations: 106     Fields:    Translation:HumansAnimalsCells
  59. Nikolic B, Lee S, Bronson RT, Grusby MJ, Sykes M. Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets. J Clin Invest. 2000 May; 105(9):1289-98. PMID: 10792004; PMCID: PMC315439.
    Citations: 72     Fields:    Translation:AnimalsCells
  60. Reimold AM, Etkin A, Clauss I, Perkins A, Friend DS, Zhang J, Horton HF, Scott A, Orkin SH, Byrne MC, Grusby MJ, Glimcher LH. An essential role in liver development for transcription factor XBP-1. Genes Dev. 2000 Jan 15; 14(2):152-7. PMID: 10652269; PMCID: PMC316338.
    Citations: 206     Fields:    Translation:AnimalsCells
  61. Kaplan MH, Wurster AL, Smiley ST, Grusby MJ. Stat6-dependent and -independent pathways for IL-4 production. J Immunol. 1999 Dec 15; 163(12):6536-40. PMID: 10586046.
    Citations: 21     Fields:    Translation:AnimalsCells
  62. Kriebel P, Patel BK, Nelson SA, Grusby MJ, LaRochelle WJ. Consequences of Stat6 deletion on Sis/PDGF- and IL-4-induced proliferation and transcriptional activation in murine fibroblasts. Oncogene. 1999 Dec 02; 18(51):7294-302. PMID: 10602484.
    Citations: 5     Fields:    Translation:AnimalsCells
  63. Shimamura M, Huang YY, Suda Y, Kusumoto S, Sato K, Grusby MJ, Sato H, Nakayama T, Taniguchi M. Positive selection of NKT cells by CD1(+), CD11c(+) non-lymphoid cells residing in the extrathymic organs. Eur J Immunol. 1999 12; 29(12):3962-70. PMID: 10602005.
    Citations: 4     Fields:    Translation:AnimalsCells
  64. Holz A, Bot A, Coon B, Wolfe T, Grusby MJ, von Herrath MG. Disruption of the STAT4 signaling pathway protects from autoimmune diabetes while retaining antiviral immune competence. J Immunol. 1999 Nov 15; 163(10):5374-82. PMID: 10553062.
    Citations: 23     Fields:    Translation:AnimalsCells
  65. Homann D, Holz A, Bot A, Coon B, Wolfe T, Petersen J, Dyrberg TP, Grusby MJ, von Herrath MG. Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway. Immunity. 1999 Oct; 11(4):463-72. PMID: 10549628.
    Citations: 52     Fields:    Translation:AnimalsCells
  66. Ong CJ, Ip S, Teh SJ, Wong C, Jirik FR, Grusby MJ, Teh HS. A role for T helper 2 cells in mediating skin fibrosis in tight-skin mice. Cell Immunol. 1999 Aug 25; 196(1):60-8. PMID: 10486156.
    Citations: 20     Fields:    Translation:AnimalsCells
  67. Wild J, Grusby MJ, Schirmbeck R, Reimann J. Priming MHC-I-restricted cytotoxic T lymphocyte responses to exogenous hepatitis B surface antigen is CD4+ T cell dependent. J Immunol. 1999 Aug 15; 163(4):1880-7. PMID: 10438922.
    Citations: 8     Fields:    Translation:AnimalsCells
  68. Morse HC, McCarty T, Giese NA, Taddesse-Heath L, Grusby MJ. STAT6-deficient mice exhibit normal induction of murine AIDS and expression of immunoglobulin E following infection with LP-BM5 murine leukemia viruses. J Virol. 1999 Aug; 73(8):7093-5. PMID: 10400816; PMCID: PMC112803.
    Citations: 6     Fields:    Translation:AnimalsCells
  69. Behar SM, Dascher CC, Grusby MJ, Wang CR, Brenner MB. Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis. J Exp Med. 1999 Jun 21; 189(12):1973-80. PMID: 10377193; PMCID: PMC2192974.
    Citations: 117     Fields:    Translation:AnimalsCells
  70. Kim JI, Ho IC, Grusby MJ, Glimcher LH. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity. 1999 Jun; 10(6):745-51. PMID: 10403649.
    Citations: 136     Fields:    Translation:AnimalsCells
  71. Schön MP, Arya A, Murphy EA, Adams CM, Strauch UG, Agace WW, Marsal J, Donohue JP, Her H, Beier DR, Olson S, Lefrancois L, Brenner MB, Grusby MJ, Parker CM. Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice. J Immunol. 1999 Jun 01; 162(11):6641-9. PMID: 10352281.
    Citations: 181     Fields:    Translation:AnimalsCells
  72. Eberl G, Lees R, Smiley ST, Taniguchi M, Grusby MJ, MacDonald HR. Tissue-specific segregation of CD1d-dependent and CD1d-independent NK T cells. J Immunol. 1999 Jun 01; 162(11):6410-9. PMID: 10352254.
    Citations: 86     Fields:    Translation:AnimalsCells
  73. Shi HN, Grusby MJ, Nagler-Anderson C. Orally induced peripheral nonresponsiveness is maintained in the absence of functional Th1 or Th2 cells. J Immunol. 1999 May 01; 162(9):5143-8. PMID: 10227985.
    Citations: 4     Fields:    Translation:AnimalsCells
  74. Kim JI, Li T, Ho IC, Grusby MJ, Glimcher LH. Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proc Natl Acad Sci U S A. 1999 Mar 30; 96(7):3781-5. PMID: 10097114; PMCID: PMC22371.
    Citations: 76     Fields:    Translation:AnimalsCells
  75. Claesson MH, Bregenholt S, Bonhagen K, Thoma S, Möller P, Grusby MJ, Leithäuser F, Nissen MH, Reimann J. Colitis-inducing potency of CD4+ T cells in immunodeficient, adoptive hosts depends on their state of activation, IL-12 responsiveness, and CD45RB surface phenotype. J Immunol. 1999 Mar 15; 162(6):3702-10. PMID: 10092833.
    Citations: 21     Fields:    Translation:AnimalsCells
  76. Ho IC, Kaplan MH, Jackson-Grusby L, Glimcher LH, Grusby MJ. Marking IL-4-producing cells by knock-in of the IL-4 gene. Int Immunol. 1999 Feb; 11(2):243-7. PMID: 10069422.
    Citations: 2     Fields:    Translation:AnimalsCells
  77. Schofield L, McConville MJ, Hansen D, Campbell AS, Fraser-Reid B, Grusby MJ, Tachado SD. CD1d-restricted immunoglobulin G formation to GPI-anchored antigens mediated by NKT cells. Science. 1999 Jan 08; 283(5399):225-9. PMID: 9880256.
    Citations: 90     Fields:    Translation:AnimalsCells
  78. Hoey T, Grusby MJ. STATs as mediators of cytokine-induced responses. Adv Immunol. 1999; 71:145-62. PMID: 9917912.
    Citations: 9     Fields:    Translation:AnimalsCells
  79. Lowe ME, Kaplan MH, Jackson-Grusby L, D'Agostino D, Grusby MJ. Decreased neonatal dietary fat absorption and T cell cytotoxicity in pancreatic lipase-related protein 2-deficient mice. J Biol Chem. 1998 Nov 20; 273(47):31215-21. PMID: 9813028.
    Citations: 34     Fields:    Translation:AnimalsCells
  80. Burdin N, Brossay L, Koezuka Y, Smiley ST, Grusby MJ, Gui M, Taniguchi M, Hayakawa K, Kronenberg M. Selective ability of mouse CD1 to present glycolipids: alpha-galactosylceramide specifically stimulates V alpha 14+ NK T lymphocytes. J Immunol. 1998 Oct 01; 161(7):3271-81. PMID: 9759842.
    Citations: 139     Fields:    Translation:AnimalsCells
  81. Kaplan MH, Wurster AL, Grusby MJ. A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells. J Exp Med. 1998 Sep 21; 188(6):1191-6. PMID: 9743537; PMCID: PMC2212539.
    Citations: 40     Fields:    Translation:AnimalsCells
  82. Oukka M, Ho IC, de la Brousse FC, Hoey T, Grusby MJ, Glimcher LH. The transcription factor NFAT4 is involved in the generation and survival of T cells. Immunity. 1998 Sep; 9(3):295-304. PMID: 9768749.
    Citations: 87     Fields:    Translation:AnimalsCells
  83. Sendobry SM, Cornicelli JA, Welch K, Grusby MJ, Daugherty A. Absence of T lymphocyte-derived cytokines fails to diminish macrophage 12/15-lipoxygenase expression in vivo. J Immunol. 1998 Aug 01; 161(3):1477-82. PMID: 9686614.
    Citations: 5     Fields:    Translation:AnimalsCells
  84. Linehan LA, Warren WD, Thompson PA, Grusby MJ, Berton MT. STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination. J Immunol. 1998 Jul 01; 161(1):302-10. PMID: 9647237.
    Citations: 38     Fields:    Translation:AnimalsCells
  85. Kaplan MH, Grusby MJ. Regulation of T helper cell differentiation by STAT molecules. J Leukoc Biol. 1998 Jul; 64(1):2-5. PMID: 9665267.
    Citations: 28     Fields:    Translation:AnimalsCells
  86. Kaplan MH, Daniel C, Schindler U, Grusby MJ. Stat proteins control lymphocyte proliferation by regulating p27Kip1 expression. Mol Cell Biol. 1998 Apr; 18(4):1996-2003. PMID: 9528771; PMCID: PMC121429.
    Citations: 26     Fields:    Translation:AnimalsCells
  87. Kuperman D, Schofield B, Wills-Karp M, Grusby MJ. Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. J Exp Med. 1998 Mar 16; 187(6):939-48. PMID: 9500796; PMCID: PMC2212182.
    Citations: 120     Fields:    Translation:Animals
  88. Ranger AM, Grusby MJ, Hodge MR, Gravallese EM, de la Brousse FC, Hoey T, Mickanin C, Baldwin HS, Glimcher LH. The transcription factor NF-ATc is essential for cardiac valve formation. Nature. 1998 Mar 12; 392(6672):186-90. PMID: 9515964.
    Citations: 191     Fields:    Translation:AnimalsCells
  89. Kaplan MH, Whitfield JR, Boros DL, Grusby MJ. Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response. J Immunol. 1998 Feb 15; 160(4):1850-6. PMID: 9469446.
    Citations: 87     Fields:    Translation:AnimalsCells
  90. Ranger AM, Hodge MR, Gravallese EM, Oukka M, Davidson L, Alt FW, de la Brousse FC, Hoey T, Grusby M, Glimcher LH. Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc. Immunity. 1998 Jan; 8(1):125-34. PMID: 9462518.
    Citations: 83     Fields:    Translation:AnimalsCells
  91. Croy BA, Ashkar AA, Foster RA, DiSanto JP, Magram J, Carson D, Gendler SJ, Grusby MJ, Wagner N, Muller W, Guimond MJ. Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy. J Reprod Immunol. 1997 Nov 15; 35(2):111-33. PMID: 9421796.
    Citations: 13     Fields:    Translation:AnimalsCells
  92. Smiley ST, Stitt TN, Grusby MJ. Cross-linking of protein S bound to lymphocytes promotes aggregation and inhibits proliferation. Cell Immunol. 1997 Nov 01; 181(2):120-6. PMID: 9398399.
    Citations: 4     Fields:    Translation:AnimalsCells
  93. Herold KC, Lu J, Rulifson I, Vezys V, Taub D, Grusby MJ, Bluestone JA. Regulation of C-C chemokine production by murine T cells by CD28/B7 costimulation. J Immunol. 1997 Nov 01; 159(9):4150-3. PMID: 9379007.
    Citations: 13     Fields:    Translation:AnimalsCells
  94. Smiley ST, Boyer SN, Heeb MJ, Griffin JH, Grusby MJ. Protein S is inducible by interleukin 4 in T cells and inhibits lymphoid cell procoagulant activity. Proc Natl Acad Sci U S A. 1997 Oct 14; 94(21):11484-9. PMID: 9326636; PMCID: PMC23513.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  95. Smiley ST, Grusby MJ. Dual-receptor T cells expressing one self-restricted TCR. Scand J Immunol. 1997 Jun; 45(6):726-30. PMID: 9201314.
    Citations: 2     Fields:    Translation:AnimalsCells
  96. Grusby MJ. Stat4- and Stat6-deficient mice as models for manipulating T helper cell responses. Biochem Soc Trans. 1997 May; 25(2):359-60. PMID: 9191117.
    Citations: 7     Fields:    Translation:AnimalsCells
  97. Lee RS, Grusby MJ, Laufer TM, Colvin R, Glimcher LH, Auchincloss H. CD8+ effector cells responding to residual class I antigens, with help from CD4+ cells stimulated indirectly, cause rejection of "major histocompatibility complex-deficient" skin grafts. Transplantation. 1997 Apr 27; 63(8):1123-33. PMID: 9133474.
    Citations: 11     Fields:    Translation:AnimalsCells
  98. Smiley ST, Kaplan MH, Grusby MJ. Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells. Science. 1997 Feb 14; 275(5302):977-9. PMID: 9020080.
    Citations: 137     Fields:    Translation:AnimalsCells
  99. Kaplan MH, Boyer SN, Grusby MJ. Genomic organization of the murine CTL lipase gene. Genomics. 1996 Aug 01; 35(3):606-9. PMID: 8812501.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  100. Kaplan MH, Sun YL, Hoey T, Grusby MJ. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature. 1996 Jul 11; 382(6587):174-7. PMID: 8700209.
    Citations: 330     Fields:    Translation:AnimalsCells
  101. Hodge MR, Ranger AM, Charles de la Brousse F, Hoey T, Grusby MJ, Glimcher LH. Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice. Immunity. 1996 Apr; 4(4):397-405. PMID: 8612134.
    Citations: 140     Fields:    Translation:AnimalsCells
  102. Kaplan MH, Schindler U, Smiley ST, Grusby MJ. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity. 1996 Mar; 4(3):313-9. PMID: 8624821.
    Citations: 452     Fields:    Translation:AnimalsCells
  103. Steele DJ, Laufer TM, Smiley ST, Ando Y, Grusby MJ, Glimcher LH, Auchincloss H. Two levels of help for B cell alloantibody production. J Exp Med. 1996 Feb 01; 183(2):699-703. PMID: 8627185; PMCID: PMC2192460.
    Citations: 59     Fields:    Translation:AnimalsCells
  104. Reimold AM, Grusby MJ, Kosaras B, Fries JW, Mori R, Maniwa S, Clauss IM, Collins T, Sidman RL, Glimcher MJ, Glimcher LH. Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice. Nature. 1996 Jan 18; 379(6562):262-5. PMID: 8538792.
    Citations: 86     Fields:    Translation:AnimalsCells
  105. Smiley ST, Rudensky AY, Glimcher LH, Grusby MJ. Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes. Proc Natl Acad Sci U S A. 1996 Jan 09; 93(1):241-4. PMID: 8552613; PMCID: PMC40214.
    Citations: 6     Fields:    Translation:AnimalsCells
  106. Tarleton RL, Grusby MJ, Postan M, Glimcher LH. Trypanosoma cruzi infection in MHC-deficient mice: further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease. Int Immunol. 1996 Jan; 8(1):13-22. PMID: 8671585.
    Citations: 50     Fields:    Translation:AnimalsCellsPHPublic Health
  107. Chakkalath HR, Theodos CM, Markowitz JS, Grusby MJ, Glimcher LH, Titus RG. Class II major histocompatibility complex-deficient mice initially control an infection with Leishmania major but succumb to the disease. J Infect Dis. 1995 May; 171(5):1302-8. PMID: 7751707.
    Citations: 10     Fields:    Translation:AnimalsCells
  108. Wecker H, Grusby MJ, Auchincloss H. Effector cells must recognize antigens expressed in the graft to cause efficient skin graft rejection in SCID mice. Transplantation. 1995 Apr 27; 59(8):1223-7. PMID: 7732570.
    Citations: 1     Fields:    Translation:AnimalsCells
  109. Smiley ST, Laufer TM, Lo D, Glimcher LH, Grusby MJ. Transgenic mice expressing MHC class II molecules with truncated A beta cytoplasmic domains reveal signaling-independent defects in antigen presentation. Int Immunol. 1995 Apr; 7(4):665-77. PMID: 7547694.
    Citations: 8     Fields:    Translation:AnimalsCells
  110. Grusby MJ, Glimcher LH. Immune responses in MHC class II-deficient mice. Annu Rev Immunol. 1995; 13:417-35. PMID: 7612230.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  111. Avery AC, Markowitz JS, Grusby MJ, Glimcher LH, Cantor H. Activation of T cells by superantigen in class II-negative mice. J Immunol. 1994 Dec 01; 153(11):4853-61. PMID: 7963549.
    Citations: 12     Fields:    Translation:AnimalsCells
  112. Takahama Y, Suzuki H, Katz KS, Grusby MJ, Singer A. Positive selection of CD4+ T cells by TCR ligation without aggregation even in the absence of MHC. Nature. 1994 Sep 01; 371(6492):67-70. PMID: 7915400.
    Citations: 20     Fields:    Translation:AnimalsCells
  113. Matsushima GK, Taniike M, Glimcher LH, Grusby MJ, Frelinger JA, Suzuki K, Ting JP. Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy. Cell. 1994 Aug 26; 78(4):645-56. PMID: 8069913.
    Citations: 35     Fields:    Translation:AnimalsCells
  114. Mombaerts P, Mizoguchi E, Ljunggren HG, Iacomini J, Ishikawa H, Wang L, Grusby MJ, Glimcher LH, Winn HJ, Bhan AK, et al. Peripheral lymphoid development and function in TCR mutant mice. Int Immunol. 1994 Jul; 6(7):1061-70. PMID: 7947457.
    Citations: 27     Fields:    Translation:AnimalsCells
  115. Linette GP, Grusby MJ, Hedrick SM, Hansen TH, Glimcher LH, Korsmeyer SJ. Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points. Immunity. 1994 Jun; 1(3):197-205. PMID: 7889408.
    Citations: 68     Fields:    Translation:AnimalsCells
  116. Jevnikar AM, Grusby MJ, Glimcher LH. Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice. J Exp Med. 1994 Apr 01; 179(4):1137-43. PMID: 7908320; PMCID: PMC2191453.
    Citations: 50     Fields:    Translation:AnimalsCells
  117. Lee RS, Grusby MJ, Glimcher LH, Winn HJ, Auchincloss H. Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo. J Exp Med. 1994 Mar 01; 179(3):865-72. PMID: 8113680; PMCID: PMC2191395.
    Citations: 43     Fields:    Translation:AnimalsCells
  118. Crump AL, Grusby MJ, Glimcher LH, Cantor H. Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10739-43. PMID: 7902569; PMCID: PMC47853.
    Citations: 15     Fields:    Translation:AnimalsCells
  119. Bigby M, Markowitz JS, Bleicher PA, Grusby MJ, Simha S, Siebrecht M, Wagner M, Nagler-Anderson C, Glimcher LH. Most gamma delta T cells develop normally in the absence of MHC class II molecules. J Immunol. 1993 Nov 01; 151(9):4465-75. PMID: 8409413.
    Citations: 18     Fields:    Translation:AnimalsCells
  120. Mombaerts P, Mizoguchi E, Grusby MJ, Glimcher LH, Bhan AK, Tonegawa S. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell. 1993 Oct 22; 75(2):274-82. PMID: 8104709.
    Citations: 204     Fields:    Translation:AnimalsCells
  121. Laufer TM, von Herrath MG, Grusby MJ, Oldstone MB, Glimcher LH. Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient mice. J Exp Med. 1993 Aug 01; 178(2):589-96. PMID: 8101862; PMCID: PMC2191112.
    Citations: 12     Fields:    Translation:AnimalsCells
  122. Todd MD, Grusby MJ, Lederer JA, Lacy E, Lichtman AH, Glimcher LH. Transcription of the interleukin 4 gene is regulated by multiple promoter elements. J Exp Med. 1993 Jun 01; 177(6):1663-74. PMID: 8496684; PMCID: PMC2191048.
    Citations: 22     Fields:    Translation:AnimalsCells
  123. Grusby MJ, Auchincloss H, Lee R, Johnson RS, Spencer JP, Zijlstra M, Jaenisch R, Papaioannou VE, Glimcher LH. Mice lacking major histocompatibility complex class I and class II molecules. Proc Natl Acad Sci U S A. 1993 May 01; 90(9):3913-7. PMID: 8483910; PMCID: PMC46416.
    Citations: 73     Fields:    Translation:AnimalsCells
  124. Auchincloss H, Lee R, Shea S, Markowitz JS, Grusby MJ, Glimcher LH. The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3373-7. PMID: 8475083; PMCID: PMC46302.
    Citations: 64     Fields:    Translation:AnimalsCells
  125. Markowitz JS, Auchincloss H, Grusby MJ, Glimcher LH. Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice. Proc Natl Acad Sci U S A. 1993 Apr 01; 90(7):2779-83. PMID: 8464889; PMCID: PMC46179.
    Citations: 33     Fields:    Translation:AnimalsCells
  126. Markowitz JS, Rogers PR, Grusby MJ, Parker DC, Glimcher LH. B lymphocyte development and activation independent of MHC class II expression. J Immunol. 1993 Feb 15; 150(4):1223-33. PMID: 8432977.
    Citations: 15     Fields:    Translation:AnimalsCells
  127. Cantor H, Crump AL, Raman VK, Liu H, Markowitz JS, Grusby MJ, Glimcher LH. Immunoregulatory effects of superantigens: interactions of staphylococcal enterotoxins with host MHC and non-MHC products. Immunol Rev. 1993 Feb; 131:27-42. PMID: 8486393.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  128. Grusby MJ, Johnson RS, Papaioannou VE, Glimcher LH. Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice. Science. 1991 Sep 20; 253(5026):1417-20. PMID: 1910207.
    Citations: 224     Fields:    Translation:AnimalsCells
  129. Finn PW, Kara CJ, Grusby MJ, Folsom V, Glimcher LH. Upstream elements of the MHC class II E beta gene active in B cells. J Immunol. 1991 Jun 01; 146(11):4011-5. PMID: 1903416.
    Citations: 6     Fields:    Translation:AnimalsCells
  130. Grusby MJ, Mitchell SC, Nabavi N, Glimcher LH. Casein expression in cytotoxic T lymphocytes. Proc Natl Acad Sci U S A. 1990 Sep; 87(17):6897-901. PMID: 2395885; PMCID: PMC54645.
    Citations: 13     Fields:    Translation:AnimalsCells
  131. Grusby MJ, Mitchell SC, Glimcher LH. Molecular cloning of mouse cathepsin D. Nucleic Acids Res. 1990 Jul 11; 18(13):4008. PMID: 2374732; PMCID: PMC331124.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  132. Grusby MJ, Nabavi N, Wong H, Dick RF, Bluestone JA, Schotz MC, Glimcher LH. Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase. Cell. 1990 Feb 09; 60(3):451-9. PMID: 2302735.
    Citations: 19     Fields:    Translation:AnimalsCells
  133. Nabavi N, Grusby MJ, Finn PW, Wolgemuth DJ, Glimcher LH. Identification of an IL-4-inducible gene expressed in differentiating lymphocytes and male germ cells. Dev Immunol. 1990; 1(1):19-30. PMID: 2136202; PMCID: PMC2275816.
    Citations:    Fields:    Translation:AnimalsCells
  134. Pierce SK, Morris JF, Grusby MJ, Kaumaya P, van Buskirk A, Srinivasan M, Crump B, Smolenski LA. Antigen-presenting function of B lymphocytes. Immunol Rev. 1988 Dec; 106:149-80. PMID: 3075588.
    Citations: 34     Fields:    Translation:AnimalsCells
  135. Grusby MJ, Pierce SK. Induction of antigen-specific antibody responses by nonspecific T cell-derived helper factors. Immunol Res. 1986; 5(3):201-9. PMID: 2952746.
    Citations:    Fields:    Translation:AnimalsCells
  136. Jelachich ML, Grusby MJ, Clark D, Tasch D, Margoliash E, Pierce SK. Synergistic effects of antigen and soluble T-cell factors in B-lymphocyte activation. Proc Natl Acad Sci U S A. 1984 Sep; 81(17):5537-41. PMID: 6089211; PMCID: PMC391741.
    Citations: 9     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.